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https://www.readbyqxmd.com/read/27899800/creating-a-pandemic-of-health-what-is-the-role-of-digital-technologies
#1
Alejandro R Jadad
Imagine a world in which every human being is healthy until the last breath. Thanks to the fast penetration of digital technologies in every region of the planet, this seemingly utopian scenario is not only feasible but also potentially viable. Now that digital technologies have provided almost full interconnectivity among all humans, they should be used to meet key challenges to ensure that health is created and that it spreads to reach every person on earth. The objective of this article is to describe and trigger a serious discussion of such challenges, which include: adopting a new concept of health; positioning self-rated health as the main outcome of the system; creating a health-oriented model to guide service provision; facilitating the identification, scaling up, and sustaining of innovations that can create and spread health; promoting a culture of health promotion; and encouraging the emergence of Precision Health...
November 2016: Journal of Public Health Policy
https://www.readbyqxmd.com/read/27892602/the-analog-blanking-period-of-implantable-cardiac-rhythm-devices
#2
S Serge Barold, Andreas Kucher
BACKGROUND: Analog blanking periods (BP) that hold down the display of electrograms (EGM) in cardiac rhythm devices have received much less attention than the well-known digital blanking periods which do not influence the EGM display. In Biotronik devices, when a paced event initiates an analog BP in one chamber [right atrium (RA), right ventricle (RV) or left ventricle (LV)], an identical cross-chamber analog BP starts in the other 2 chambers. METHODOLOGY: All clinical observations were recorded from patients with Biotronik devices...
November 28, 2016: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/27873738/sensitive-skin-and-the-influence-of-female-hormone-fluctuations-results-from-a-cross-sectional-digital-survey-in-the-dutch-population
#3
Denise Falcone, Renee J H Richters, Natallia E Uzunbajakava, Piet E J Van Erp, Peter C M Van De Kerkhof
Sensitive skin is a widespread condition, which is most frequently reported by women. Changing hormone levels during the menstrual cycle and menopause have been suggested among the stimuli triggering sensitive skin. To investigate the perceived influence of fluctuating hormone levels on self-assessed sensitive skin, including symptoms and stimuli linked to skin sensitivity, as well as potential changes in facial and body skin and sensitive body parts, depending on hormonal status. A digital questionnaire was distributed to a population of women aged 20-65 years old...
November 21, 2016: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/27864167/testing-the-feasibility-of-remote-patient-monitoring-in-prenatal-care-using-a-mobile-app-and-connected-devices-a-prospective-observational-trial
#4
Kathryn I Marko, Jill M Krapf, Andrew C Meltzer, Julia Oh, Nihar Ganju, Anjali G Martinez, Sheetal G Sheth, Nancy D Gaba
BACKGROUND: Excessive weight gain and elevated blood pressure are significant risk factors for adverse pregnancy outcomes such as gestational diabetes, premature birth, and preeclampsia. More effective strategies to facilitate adherence to gestational weight gain goals and monitor blood pressure may have a positive health benefit for pregnant women and their babies. The impact of utilizing a remote patient monitoring system to monitor blood pressure and weight gain as a component of prenatal care has not been previously assessed...
November 18, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27859389/influence-of-gold-nanoparticles-on-wound-healing-treatment-in-rat-model-photobiomodulation-therapy
#5
PikSuan Lau, Noriah Bidin, Shumaila Islam, Wan Norsyuhada Binti Wan Mohd Shukri, Nurlaily Zakaria, Nurfatin Musa, Ganesan Krishnan
BACKGROUND AND OBJECTIVE: The aim of this study is to investigate the effect of gold nanoparticles (AuNPs) in photobiomodulation therapy (PBMT) on wound healing process. MATERIALS AND METHODS: AuNPs are synthesized by Q-switched Nd:YAG laser ablation technique. Cutaneous wound are induced on 45 Sprague Dawley rats on its dorsal part and then randomly divided into three groups. One group serves as non-treatment group (GC) and another two groups are subjected to AuNPs with and without PBMT...
November 12, 2016: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/27857286/high-speed-time-resolved-laser-scanning-microscopy-using-the-line-to-pixel-referencing-method
#6
Jiheun Ryu, Jayul Kim, Hyunjun Kim, Jae-Heon Jeong, Hak-Jun Lee, Hongki Yoo, Dae-Gab Gweon
Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique to visualize photophysical characteristics of biological targets. However, conventional FLIM methods have some limitations that restrict obtaining high-precision images in real time. Here, we propose a high-speed time-resolved laser-scanning microscopy by incorporating a novel line-to-pixel referencing method into the previously suggested analog mean-delay (AMD) method. The AMD method dramatically enhances the photon accumulation speed for achieving the certain precision compared to the time-correlated single-photon counting (TCSPC) method while maintaining high photon efficiency...
November 10, 2016: Applied Optics
https://www.readbyqxmd.com/read/27843364/radial-extracorporeal-shockwave-therapy-for-the-treatment-of-finger-tenosynovitis-trigger-digit
#7
Nikos Malliaropoulos, Rosanna Jury, Debasish Pyne, Nat Padhiar, Jennifer Turner, Vasileios Korakakis, Maria Meke, Heinz Lohrer
INTRODUCTION: Stenosing tenosynovitis that is characterized by the inability to flex the digit smoothly, usually leads to prolonged rehabilitation or surgery. STUDY DESIGN: This case series is a retrospective cohort study. PURPOSE: The aim of this case series was to evaluate the effectiveness of radial extracorporeal shockwave therapy (rESWT) for the treatment of stenosing tenosynovitis of the digital flexor tendon (trigger digit). METHODS: A retrospective analysis of 44 patients (49 fingers) treated with an individually adapted rESWT protocol was conducted...
2016: Open Access Journal of Sports Medicine
https://www.readbyqxmd.com/read/27812300/impact-observatory-tracking-the-evolution-of-clinical-trial-data-sharing-and-research-integrity
#8
REVIEW
Karmela Krleža-Jerić, Mirko Gabelica, Rita Banzi, Marina Krnić Martinić, Bibiana Pulido, Mersiha Mahmić-Kaknjo, Ludovic Reveiz, Josip Šimić, Ana Utrobičić, Irena Hrgović
INTRODUCTION: The opening of research data is emerging thanks to the increasing possibilities of digital technology. The opening of clinical trial (CT) data is a part of this process, expected to have positive scientific, ethical, health, and economic impacts thus contributing to research integrity. The January 2016 proposal by the International Council of Medical Journal Editors triggered ample discussion about CT data sharing and reconfirmed the need for an ongoing assessment of its dynamics...
October 15, 2016: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/27802737/vertical-wicking-tester-for-monitoring-water-transportation-behavior-in-fibrous-assembly
#9
Pratibha Singh, Arobindo Chatterjee, Subrata Ghosh
An instrument based on the principle of change of resistance of fibrous assembly on wetting has been developed for precise monitoring of the water transportation behaviour in the fibrous assemblies. The conducting probes sense the change in resistance of a dry fibrous assembly on wetting. This change in resistance generates analog signals which trigger an amplifying circuit. This circuit produces an enlarged copy of the received signals which are further converted to digital signals by a Darlington pair and are encoded to measurable quantity with the help of a microcontroller...
October 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27783840/short-term-versus-long-term-outcomes-after-open-or-percutaneous-release-for-trigger-thumb
#10
Hui-Kuang Huang, Jung-Pan Wang, Chin-Jung Lin, Yi-Chao Huang, Tung-Fu Huang, Ming-Chau Chang
Good outcomes have been reported after both open and percutaneous surgery to release trigger thumb. This study evaluated short-term and long-term outcomes after treatment of trigger thumb with open or percutaneous release. A total of 126 trigger thumbs in 107 patients were reviewed from 2009 to 2012. Short-term (3 months) and long-term results (2 years) and complications of open release (58 digits) and percutaneous release (68 digits) were recorded and compared. Short-term complications included pain occurring in 9 digits (15...
October 25, 2016: Orthopedics
https://www.readbyqxmd.com/read/27782599/note-a-dual-chip-stroboscopic-pulsed-radar-for-probing-passive-sensors
#11
F Minary, D Rabus, G Martin, J-M Friedt
Stroboscopy provides an energy and computationally efficient means of sampling radiofrequency and microwave signals assumed to be reproducible under external excitation. While well known for impulse mode RADAR receivers, we here investigate its use for interrogating surface acoustic wave (SAW) transducers acting as passive cooperative targets. Amongst the originality of the implementation is the need to keep phase coherence between successive pulse generations which last up to tens of the radiofrequency periods to optimally transfer energy to the transducer...
September 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27778059/-intelligent-operating-room-suite-from-passive-medical-devices-to-the-self-thinking-cognitive-surgical-assistant
#12
H G Kenngott, M Wagner, A A Preukschas, B P Müller-Stich
Modern operating room (OR) suites are mostly digitally connected but until now the primary focus was on the presentation, transfer and distribution of images. Device information and processes within the operating theaters are barely considered. Cognitive assistance systems have triggered a fundamental rethinking in the automotive industry as well as in logistics. In principle, tasks in the OR, some of which are highly repetitive, also have great potential to be supported by automated cognitive assistance via a self-thinking system...
December 2016: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/27759738/the-relationship-between-il-6-et-1-and-cerebral-vasospasm-in-experimental-rabbit-subarachnoid-hemorrhage
#13
Davide Croci, Edin Nevzati, Hiroki Danura, Salome Schöpf, Javier Fandino, Serge Marbacher, Carl Muroi
BACKGROUND: In subarachnoid hemorrhage (SAH), occurrence of cerebral vasospasm (CVS) mediated by endothelin (ET)-1 might be a result of a compartmental inflammatory response with interleukin (IL)-6 release. We aim to investigate the relationship between ET-1 and IL-6 in association of CVS. METHODS: A total of 24 New Zealand white rabbits where randomly allocated into 3 groups: SAH (n=10), IL-6 (n=10), and sham (n=4). SAH was induced by a closed cranium extracranial-intracranial shunt model...
October 19, 2016: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27750396/impaired-oligodendroglial-turnover-is-associated-with-myelin-pathology-in-focal-cortical-dysplasia-and-tuberous-sclerosis-complex
#14
Theresa Scholl, Angelika Mühlebner, Gerda Ricken, Victoria Gruber, Anna Fabing, Sharon Samueli, Gudrun Gröppel, Christian Dorfer, Thomas Czech, Johannes A Hainfellner, Avanita S Prabowo, Roy J Reinten, Lisette Hoogendijk, Jasper J Anink, Eleonora Aronica, Martha Feucht
Conventional antiepileptic drugs suppress the excessive firing of neurons during seizures. In drug-resistant patients, treatment failure indicates an alternative important epileptogenic trigger. Two epilepsy-associated pathologies show myelin deficiencies in seizure-related brain regions: Focal Cortical Dysplasia IIB (FCD) and cortical tubers in Tuberous Sclerosis Complex (TSC). Studies uncovering white matter-pathology mechanisms are therefore urgently needed to gain more insight into epileptogenesis, the propensity to maintain seizures, and their associated comorbidities such as cognitive defects...
October 17, 2016: Brain Pathology
https://www.readbyqxmd.com/read/27742430/non-contrast-enhanced-mr-angiography-in-the-diagnosis-of-budd-chiari-syndrome-bcs-compared-with-digital-subtraction-angiography-dsa-preliminary-results
#15
Chun Yang, Ceng Li, Mengsu Zeng, Xin Lu, Jingjing Li, Jiali Wang, Muhammad Umair Sami, Kai Xu
Non-CE MRA techniques (true steady-state free-precession, SSFP) have been used effectively for the selective visualization of the portal venous system and inferior vena cava. Budd-Chiari Syndrome (BCS) encompasses a number of conditions that cause the obstruction of the hepatic outflow tract from the small hepatic veins to the junction of the inferior vena cava (IVC) and right atrium. The purpose of this study was to diagnose BCS with IVC obstruction using respiratory triggered three-dimensional (3D) true SSFP with T-SLIP and compare to digital subtraction angiography (DSA)...
October 11, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27726447/exposure-of-a-tendon-extracellular-matrix-to-synovial-fluid-triggers-endogenous-and-engrafted-cell-death-a-mechanism-for-failed-healing-of-intrathecal-tendon-injuries
#16
Elaine R Garvican, Mazdak Salavati, Roger K W Smith, Jayesh Dudhia
AIM: The purpose of this study was to investigate the effect of normal synovial fluid (SF) on exposed endogenous tendon-derived cells (TDCs) and engrafted mesenchymal stem cells (MSCs) within the tendon extracellular matrix. METHODS: Explants from equine superficial digital flexor (extra-synovial) and deep digital flexor tendons (DDFTs) from the compressed, intra-synovial and the tensile, extra-synovial regions were cultured in allogeneic or autologous SF-media...
October 11, 2016: Connective Tissue Research
https://www.readbyqxmd.com/read/27723597/generation-of-stimulus-triggering-from-intracortical-spike-activity-for-brain-machine-body-interfaces-bmbis
#17
Shahab Shahdoost, Randolph Nudo, Pedram Mohseni
Brain-machine-body interfaces (BMBIs) aim to create an artificial connection in the nervous system by converting neural activity recorded from one cortical region to electrical stimuli delivered to another cortical region, spinal cord, or muscles in real-time. In particular, conditioning-mode BMBIs utilize such activity-dependent stimulation strategies to induce functional re-organization in the nervous system and promote functional recovery after injury by exploiting mechanisms underlying neuroplasticity. This paper reports on reconfigurable, field-programmable gate array (FPGA)-based implementation of a translation algorithm to extract multichannel stimulus trigger signals from intracortical neural spike activity...
October 5, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/27717978/high-resolution-ultrasound-in-the-diagnosis-of-trigger-finger-and-evaluation-of-response-to-steroid-injection
#18
Yutaka Mifune, Atsuyuki Inui, Ryosuke Sakata, Yoshifumi Harada, Fumiaki Takase, Masahiro Kurosaka, Takeshi Kokubu
OBJECTIVE: No studies have reported the use of ultrasound for the evaluation of trigger finger after steroid injection. We evaluated the clinical features and ultrasound appearance of trigger finger before and after steroid injection under ultrasound guidance. MATERIALS AND METHODS: Thirty-eight digits with triggering were included. A single steroid injection into the tendon sheath was administered. Ultrasound findings and clinical symptoms, including pain, triggering, and the Quinnell score, were analyzed before injection and at 1 and 3 weeks after injection...
December 2016: Skeletal Radiology
https://www.readbyqxmd.com/read/27698556/digital-life-storybooks-for-people-with-dementia-living-in-care-homes-an-evaluation
#19
Ponnusamy Subramaniam, Bob Woods
BACKGROUND AND AIM: There is increasing interest in using information and communication technology to help older adults with dementia to engage in reminiscence work. Now, the feasibility of such approaches is beginning to be established. The purpose of this study was to establish an evidence-base for the acceptability and efficacy of using multimedia digital life storybooks with people with dementia in care homes, in comparison with conventional life storybooks, taking into account the perspectives of people with dementia, their relatives, and care staff...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27681360/targeting-of-sebaceous-glands-to-treat-acne-by-micro-insulated-needles-with-radio-frequency-in-a-rabbit-ear-model
#20
Tae-Rin Kwon, Eun Ja Choi, Chang Taek Oh, Dong-Ho Bak, Song-I Im, Eun Jung Ko, Hyuck Ki Hong, Yeon Shik Choi, Joon Seok, Sun Young Choi, Gun Young Ahn, Beom Joon Kim
BACKGROUND AND OBJECTIVES: Many studies have investigated the application of micro-insulated needles with radio frequency (RF) to treat acne in humans; however, the use of a micro-insulated needle RF applicator has not yet been studied in an animal model. The purpose of this study was to evaluate the effectiveness of a micro-insulated needle RF applicator in a rabbit ear acne (REA) model. STUDY DESIGN/MATERIALS AND METHODS: In this study, we investigated the effect of selectively destroying the sebaceous glands using a micro-insulated needle RF applicator on the formation of comedones induced by application of 50% oleic acid and intradermal injection of P...
September 29, 2016: Lasers in Surgery and Medicine
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