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https://www.readbyqxmd.com/read/28334293/what-s-behind-a-sign-perceiving-an-arithmetic-operator-recruits-brain-circuits-for-spatial-orienting
#1
Romain Mathieu, Justine Epinat-Duclos, Monica Sigovan, Audrey Breton, Anne Cheylus, Michel Fayol, Catherine Thevenot, Jérôme Prado
Do mathematical symbols evoke spatial representations? Although behavioral studies have long demonstrated interactions between space and the processing of Arabic digits, how to interpret these results remains controversial. Here, we tested whether activity in regions supporting spatial processing contributes to the processing of symbols conveying fundamental arithmetic concepts-such as operation signs-even in the absence of associated digits. Using functional magnetic resonance imaging, we show that merely perceiving a "+" sign triggers activity in brain regions that support the orienting of spatial attention in adults...
March 14, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28319210/oculo-dento-digital-dysplasia-oddd-due-to-a-gja1-mutation-report-of-a-case-with-emphasis-on-dental-manifestations
#2
Christina Hadjichristou, Violetta Christophidou-Anastasiadou, Athina Bakopoulou, George A Tanteles, Maria A Loizidou, Kyriacos Kyriacou, Andreas Hadjisavvas, Konstantinos Michalakis, Argyris Pissiotis, Petros Koidis
Oculo-dento-digital dysplasia (ODDD) is a congenital disorder manifesting with multiple phenotypic abnormalities involving the face, eyes, teeth, and limbs in addition to neurologic symptomatology. This report aims to present a female patient with ODDD who was referred due to extensive oral restorative needs. The presence of hypoplastic enamel triggered further evaluation. Characteristic facies with hypoplastic alae nasi and syndactyly offered greater insight into the phenotype of the syndrome. Clinical suspicion was confirmed by genetic sequencing revealing heterozygous mutation in GJA1...
March 20, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/28298387/diagnosis-of-chronic-thromboembolic-pulmonary-hypertension
#3
REVIEW
Deepa Gopalan, Marion Delcroix, Matthias Held
Chronic thromboembolic pulmonary hypertension (CTEPH) is the only potentially curable form of pulmonary hypertension. Rapid and accurate diagnosis is pivotal for successful treatment. Clinical signs and symptoms can be nonspecific and risk factors such as history of venous thromboembolism may not always be present. Echocardiography is the recommended first diagnostic step. Cardiopulmonary exercise testing is a complementary tool that can help to identify patients with milder abnormalities and chronic thromboembolic disease, triggering the need for further investigation...
January 2017: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/28284968/recrudescence-of-symptoms-of-remote-ischemic-stroke-after-a-cerebral-angiogram-report-of-a-case
#4
Stephanie R Falatko, Philip G R Schmalz, Mark Harrigan
BACKGROUND: Recrudescence, or reappearance of previously resolved symptoms of ischemic stroke, may occur after physiological stress. Although this syndrome is generally thought to be uncommon, it may actually account for a significant proportion of stroke mimics. CASE DESCRIPTION: A 67-year-old man was admitted with a Hunt-Hess grade II spontaneous subarachnoid hemorrhage. He underwent a digital subtraction cerebral angiogram as part of his imaging evaluation. About 30 minutes after the procedure, he developed dysarthria, right facial droop and a right pronator drift...
March 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28275057/activity-dependent-increases-in-ca-2-i-contribute-to-digital-analog-plasticity-at-a-molluscan-synapse
#5
Bjoern Ch Ludwar, Colin G Evans, Monica Cambi, Elizabeth C Cropper
In a type of short-term plasticity that is observed in a number of systems, synaptic transmission is potentiated by depolarizing changes in the membrane potential of the presynaptic neuron prior to spike initiation. This digital-analog form of plasticity is graded. The more depolarized the neuron, the greater the increase in the efficacy of synaptic transmission. In a number of systems, including the system under investigation here, this type of modulation is calcium dependent, and its graded nature is presumably a consequence of a direct relationship between the [Ca(+2)]i and the effect on synaptic transmission...
March 8, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28263251/influence-of-cueing-and-an-attentional-strategy-on-freezing-of-gait-in-parkinson-disease-during-turning
#6
Joke Spildooren, Sarah Vercruysse, Elke Heremans, Brook Galna, Geert Verheyden, Griet Vervoort, Alice Nieuwboer
BACKGROUND AND PURPOSE: Individuals with Parkinson disease exhibit decreased axial head-pelvis rotation. Consequently, they turn more en bloc than healthy controls, which may contribute to freezing during turning. We wanted to understand the influence of auditory cueing and an attentional strategy on turning and how this related to freezing of gait (FOG). METHODS: Fifteen participants with Parkinson disease and FOG were asked to turn 180° during baseline condition, unilateral cueing, and an attentional strategy prompting to start the turn with head rotation first...
April 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/28261683/botox-combined-with-myofascial-release-physical-therapy-as-a-treatment-for-myofascial-pelvic-pain
#7
Gabriela E Halder, Lauren Scott, Allison Wyman, Nelsi Mora, Branko Miladinovic, Renee Bassaly, Lennox Hoyte
PURPOSE: To report the effects of combined onabotulinumtoxinA (Botox) injections and myofascial release physical therapy on myofascial pelvic pain (MFPP) by comparing pre- and posttreatment average pelvic pain scores, trigger points, and patient self-reported pelvic pain. Secondary outcomes were to examine posttreatment complications and determine demographic differences between patients with/without an improvement in pain. MATERIALS AND METHODS: This was an Institutional Review Board approved retrospective case series on women over 18 years with MFPP who received Botox and physical therapy between July 2006 and November 2014...
March 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28251067/comparative-clinical-study-of-ultrasound-guided-a1-pulley-release-vs-open-surgical-intervention-in-the-treatment-of-trigger-finger
#8
Vasileios S Nikolaou, Michael-Alexander Malahias, Maria-Kyriaki Kaseta, Ioannis Sourlas, George C Babis
AIM: To investigate the effectiveness of ultrasound-guided release of the first annular pulley and compare results with the conventional open operative technique. METHODS: In this prospective randomized, single-center, clinical study, 32 patients with trigger finger or trigger thumb, grade II-IV according to Green classification system, were recruited. Two groups were formed; Group A (16 patients) was treated with an ultrasound-guided percutaneous release of the affected A1 pulley under local anesthesia...
February 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28144846/virtoscan-a-mobile-low-cost-photogrammetry-setup-for-fast-post-mortem-3d-full-body-documentations-in-x-ray-computed-tomography-and-autopsy-suites
#9
Sören Kottner, Lars C Ebert, Garyfalia Ampanozi, Marcel Braun, Michael J Thali, Dominic Gascho
Injuries such as bite marks or boot prints can leave distinct patterns on the body's surface and can be used for 3D reconstructions. Although various systems for 3D surface imaging have been introduced in the forensic field, most techniques are both cost-intensive and time-consuming. In this article, we present the VirtoScan, a mobile, multi-camera rig based on close-range photogrammetry. The system can be integrated into automated PMCT scanning procedures or used manually together with lifting carts, autopsy tables and examination couch...
March 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28113512/generation-of-stimulus-triggering-from-intracortical-spike-activity-for-brain-machine-body-interfaces-bmbis
#10
Shahab Shahdoost, Randolph Nudo, Pedram Mohseni
Brain-machine-body interfaces (BMBIs) aim to create an artificial connection in the nervous system by converting neural activity recorded from one cortical region to electrical stimuli delivered to another cortical region, spinal cord, or muscles in real-time. In particular, conditioning-mode BMBIs utilize such activity-dependent stimulation strategies to induce functional re-organization in the nervous system and promote functional recovery after injury by exploiting mechanisms underlying neuroplasticity. This paper reports on reconfigurable, field-programmable gate array (FPGA)-based implementation of a translation algorithm to extract multichannel stimulus trigger signals from intracortical neural spike activity...
October 5, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28109832/a-novel-hybrid-auditory-bci-paradigm-combining-assr-and-p300
#11
Netiwit Kaongoen, Sungho Jo
BACKGROUND: Brain-computer interface (BCI) is a technology that provides an alternative way of communication by translating brain activities into digital commands. Due to the incapability of using the vision-dependent BCI for patients who have visual impairment, auditory stimuli have been used to substitute the conventional visual stimuli. NEW METHOD: This paper introduces a hybrid auditory BCI that utilizes and combines auditory steady state response (ASSR) and spatial-auditory P300 BCI to improve the performance for the auditory BCI system...
January 18, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28099274/can-any-patients-with-chronic-myeloid-leukemia-outside-of-a-clinical-trial-have-their-tyrosine-kinase-inhibitor-discontinued
#12
Michael J Mauro
PURPOSE OF REVIEW: This article critically appraises the state of treatment-free remission as a strategy for patients with chronic myeloid leukemia (CML) in deep remission after therapy with tyrosine kinase inhibitors (TKIs). RECENT FINDINGS: Approximately half of patients with CML defined fairly narrowly by trial criteria - TKI sensitive, in deep molecular remission for a defined period - can successfully maintain protective levels of response after TKI cessation...
March 2017: Current Opinion in Hematology
https://www.readbyqxmd.com/read/28076444/wiseeye-next-generation-expandable-and-programmable-camera-trap-platform-for-wildlife-research
#13
Sajid Nazir, Scott Newey, R Justin Irvine, Fabio Verdicchio, Paul Davidson, Gorry Fairhurst, René van der Wal
The widespread availability of relatively cheap, reliable and easy to use digital camera traps has led to their extensive use for wildlife research, monitoring and public outreach. Users of these units are, however, often frustrated by the limited options for controlling camera functions, the generation of large numbers of images, and the lack of flexibility to suit different research environments and questions. We describe the development of a user-customisable open source camera trap platform named 'WiseEye', designed to provide flexible camera trap technology for wildlife researchers...
2017: PloS One
https://www.readbyqxmd.com/read/28067854/quantitative-assessment-of-first-annular-pulley-and-adjacent-tissues-using-high-frequency-ultrasound
#14
Yi-Hsun Lin, Tai-Hua Yang, Shyh-Hau Wang, Fong-Chin Su
Due to a lack of appropriate image resolution, most ultrasound scanners are unable to sensitively discern the pulley tissues. To extensively investigate the properties of the A1 pulley system and the surrounding tissues for assessing trigger finger, a 30 MHz ultrasound system was implemented to perform in vitro experiments using the hypodermis, A1 pulley, and superficial digital flexor tendon (SDFT) dissected from cadavers. Ultrasound signals were acquired from both the transverse and sagittal planes of each tissue sample...
January 7, 2017: Sensors
https://www.readbyqxmd.com/read/28004437/desolvation-induced-origami-of-photocurable-polymers-by-digit-light-processing
#15
Zeang Zhao, Jiangtao Wu, Xiaoming Mu, Haosen Chen, H Jerry Qi, Daining Fang
Self-folding origami is of great interest in current research on functional materials and structures, but there is still a challenge to develop a simple method to create freestanding, reversible, and complex origami structures. This communication provides a feasible solution to this challenge by developing a method based on the digit light processing technique and desolvation-induced self-folding. In this new method, flat polymer sheets can be cured by a light field from a commercial projector with varying intensity, and the self-folding process is triggered by desolvation in water...
December 22, 2016: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28002865/percutaneous-release-procedures-trigger-finger-and-carpal-tunnel
#16
Gajan Rajeswaran, Jeremiah C Healy, Justin C Lee
Trigger digit and carpal tunnel syndrome are both conditions traditionally treated with open surgery but are potentially amenable to curative treatment using percutaneous techniques. The advantages of minimally invasive techniques are lower risk of wound breakdown and infection, quicker healing, reduced postprocedural pain, reduced complications, and a quicker return to normal activity. The advent of high-resolution ultrasound has allowed percutaneous release procedures for these conditions to be developed and performed with a potential for a reduced risk of complications and an increased likelihood of success...
November 2016: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/27999119/transgender-men-s-experiences-of-fertility-preservation-a-qualitative-study
#17
G Armuand, C Dhejne, J I Olofsson, K A Rodriguez-Wallberg
STUDY QUESTION: How do transgender men experience fertility preservation (FP) by cryopreservation of oocytes? SUMMARY ANSWER: The procedures required prior to oocyte cryopreservation, such as hormonal ovarian stimulation and transvaginal ultrasound (TVS), have a negative impact on gender dysphoria as they are closely linked to the men's female assigned sex at birth, which is incompatible with their current status. WHAT IS KNOWN ALREADY: Transgender persons often have high dissatisfaction with assigned sex-specific body features, such as the genital organs and androgen/oestrogen-responsive features...
December 19, 2016: Human Reproduction
https://www.readbyqxmd.com/read/27994539/dynamic-control-of-neurotransmitter-release-by-presynaptic-potential
#18
REVIEW
Mickael Zbili, Sylvain Rama, Dominique Debanne
Action potentials (APs) in the mammalian brain are thought to represent the smallest unit of information transmitted by neurons to their postsynaptic targets. According to this view, neuronal signaling is all-or-none or digital. Increasing evidence suggests, however, that subthreshold changes in presynaptic membrane potential before triggering the spike also determines spike-evoked release of neurotransmitter. We discuss here how analog changes in presynaptic voltage may regulate spike-evoked release of neurotransmitter through the modulation of biophysical state of voltage-gated potassium, calcium and sodium channels in the presynaptic compartment...
2016: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/27981789/comparison-of-abnormal-cell-flagging-of-the-hematology-analyzers-sysmex-xn-and-sysmex-xe-5000-in-oncohematologic-patients
#19
COMPARATIVE STUDY
J R Furundarena, M Sainz, A Uranga, L Cuevas, I Lopez, J Zubicaray, A Bizjak, N Robado, M Araiz
INTRODUCTION: Hematology analyzers should optimize flagging while minimizing false-negative results and unnecessary microscopic reviews. METHODS: We compared flagging performance of Sysmex XE-5000 and XN analyzers in oncohematologic patients. Differential counts were performed by Cellavision digital system (100 cells) and a hematologist (another 100 cells). RESULTS: First, we included 292 samples (86 with blasts): 28 acute lymphoblastic leukemia, 88 acute myeloid leukemia, 91 myelodysplastic syndromes, 45 chronic myeloproliferative neoplasms, and 40 chronic myelomonocytic leukemia...
February 2017: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/27981464/assessing-coral-health-and-disease-from-digital-photographs-and-in-situ-surveys
#20
C A Page, S N Field, F J Pollock, J B Lamb, G Shedrawi, S K Wilson
Methods for monitoring the status of marine communities are increasingly adopting the use of images captured in the field. However, it is not always clear how data collected from photographic images relate to historic data collected using traditional underwater visual census methods. Here, we compare coral health and disease data collected in situ by scuba divers with photographic images collected simultaneously at 12 coral reef sites. Five globally relevant coral diseases were detected on 194 colonies from in situ surveys and 79 colonies from photos, whilst 698 colonies from in situ surveys and 535 colonies from photos exhibited signs of compromised health other than disease...
January 2017: Environmental Monitoring and Assessment
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