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https://www.readbyqxmd.com/read/28929347/an-ethical-assessment-model-for-digital-disease-detection-technologies
#1
Kerstin Denecke
Digital epidemiology, also referred to as digital disease detection (DDD), successfully provided methods and strategies for using information technology to support infectious disease monitoring and surveillance or understand attitudes and concerns about infectious diseases. However, Internet-based research and social media usage in epidemiology and healthcare pose new technical, functional and formal challenges. The focus of this paper is on the ethical issues to be considered when integrating digital epidemiology with existing practices...
September 20, 2017: Life Sciences, Society and Policy
https://www.readbyqxmd.com/read/28924309/serum-psa-levels-in-the-indian-population-is-it-different
#2
Amit Agrawal, Shailesh Chandra Karan
BACKGROUND: Serum prostate-specific antigen (PSA) is an important tumour, marker which is widely used to trigger trans-rectal ultrasound (TRUS)-guided prostate biopsy. However, the PSA levels vary with race and ethnicity. Therefore, there is a need to have an Indian reference range. METHODS: All adult male patients meeting the inclusion and exclusion criteria were enrolled in this study. They were subjected to assessment of serum total PSA, digital rectal examination and trans-abdominal ultrasound...
April 2017: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28904635/does-orthopaedic-surgery-improve-quality-of-life-and-function-in-patients-with-mucopolysaccharidoses
#3
N Williams, D Challoumas, D M Eastwood
PURPOSE: Mucopolysaccharidoses (MPS) are a group of rare lysosomal storage disorders associated with involvement of multiple organs along with a generalised skeletal dysplasia. Both haematopoetic stem cell transplant and enzyme replacement therapy have improved the outlook for patients while surgery remains high-risk and there is little information on clinical or functional outcome to justify many of the surgical procedures performed. This paper aims to summarise the orthopaedic surgical procedures in MPS patients for which quality of life (QoL) and functional data are available and to describe additional QoL and functional measurement tools of relevance to the assessment of orthopaedic outcomes in MPS...
August 1, 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28870061/morphological-alterations-of-the-tendon-and-pulley-on-ultrasound-after-intrasynovial-injection-of-betamethasone-for-trigger-digit
#4
Mitsuhiko Takahashi, Ryosuke Sato, Kenji Kondo, Koichi Sairyo
Purpose: The aim of this study was to elucidate whether intrasynovial corticosteroid injections for trigger digit reduced the volume of the tendon and pulley on high-resolution ultrasonography. Methods: Twenty-three digits of 20 patients with trigger digit were included. Each affected finger was graded clinically according to the following classification: grade I for pre-triggering, grade II for active triggering, grade III for passive triggering, and grade IV for presence of contracture...
July 25, 2017: Ultrasonography
https://www.readbyqxmd.com/read/28856358/percutaneous-release-of-trigger-digits
#5
Noah D Weiss, Madeline B Richter
Stenosing flexor tenosynovitis, or trigger finger, has been treated with open, endoscopic, and percutaneous tendon sheath incisions. A comparison of techniques highlights increased cost, procedure time, and postoperative recovery associated with open surgical treatment. We conducted a study of the efficacy of percutaneous tendon sheath incision as a treatment for trigger digit. Using percutaneous tendon sheath incisions, a single surgeon treated 596 trigger digits (429 patients) over a 10-year period. Successful release was defined as symptom relief on follow-up, or patient request for no further treatment...
July 2017: American Journal of Orthopedics
https://www.readbyqxmd.com/read/28832206/closed-partial-flexor-digitorum-profundus-rupture-an-unusual-cause-of-pediatric-trigger-finger
#6
Shane R Jackson, Meily Tan, Kim O Taylor
BACKGROUND: Trigger finger is a common condition, causing impaired gliding of the digital flexor tendons. Chronic inflammation is the usual cause, but acute trigger finger following partial tendon laceration has also been described. METHODS: We describe the case of a four year old girl who presented with inability to flex her index finger. Operative exploration revealed a closed partial rupture of the flexor digitorum profundus tendon, catching on the A2 pulley and preventing normal tendon gliding...
September 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28819513/strengthening-and-expanding-the-capacity-of-health-worker-education-in-zambia
#7
Charles Michelo, Joseph Mumba Zulu, Moses Simuyemba, Benjamin Andrews, Max Katubulushi, Benjamin Chi, Evariste Njelesani, Bellington Vwalika, Kasonde Bowa, Margaret Maimbolwa, James Chipeta, Fastone Goma, Selestine Nzala, Sekelani Banda, John Mudenda, Yusuf Ahmed, Lotti Hachambwa, Craig Wilson, Sten Vermund, Yakub Mulla
INTRODUCTION: Zambia is facing a chronic shortage of health care workers. The paper aimed at understanding how the Medical Education Partnership Initiative (MEPI) program facilitated strengthening and expanding of the national capacity and quality of medical education as well as processes for retaining faculty in Zambia. METHODS: Data generated through documentary review, key informant interviews and observations were analyzed using a thematic approach. RESULTS: The MEPI program triggered the development of new postgraduate programs thereby increasing student enrollment...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28792176/chikungunya-fever-presenting-as-life-threatening-thrombotic-thrombocytopenic-purpura
#8
Vimal Kumar, Rujul Jain, Arvind Kumar, Neeraj Nischal, Pankaj Jorwal, Manish Soneja, Sudheer Arava, Naveet Wig
It is well known for Chikungunya fever to present as myriad of skin rash along with usual joint pain and fever, but probably this is the first case report of Chikungunya fever presenting as severe life threatening thrombotic microangiopathy, thrombotic thrombocytopenic purpura leading to multiple areas of skin necrosis, peripheral digital gangrene, haemolytic anemia, renal failure and severe thrombocytopenia with bleeding. This complication was most likely due to inhibitor autoantibody formation against ADAMTS13 triggered by chikungunya virus leading to thrombotic thrombocytopenic purpura...
July 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28776635/a-meta-analysis-of-corticosteroid-injection-for-trigger-digits-among-patients-with-diabetes
#9
Chao-Jui Chang, Shen-Peng Chang, Lo-Ting Kao, Ta-Wei Tai, I-Ming Jou
A majority of patients with diabetes have trigger digits. Initial management of symptomatic trigger digits commonly involves corticosteroid injection. However, varying outcomes have been reported for patients with diabetes who receive corticosteroid injections. The authors conducted a meta-analysis to evaluate the effect of diabetes on outcome after corticosteroid injection for trigger digit. PubMed and other Internet databases were searched for the period 1977 to 2015. Five articles, involving 381 diabetic digits and 449 non-diabetic digits, were included in the meta-analysis...
August 3, 2017: Orthopedics
https://www.readbyqxmd.com/read/28774233/disruption-of-flexor-tendon-after-intrasheath-triamcinolone-acetonide-injection-for-trigger-digits-two-case-reports
#10
Toshikazu Tanaka, Takeshi Ogawa, Takaji Yanai, Eriko Okano, Sho Kohyama, Naoyuki Ochiai
We experienced two cases of flexor tendons rupture after triamcinolone acetate (TA) injection for trigger finger. A 45-year-old man underwent injection of 40 mg of TA and 1 mL of 1% lidocaine solution into his little finger. While playing golf 3 months after the injection, he heard a popping sound, and was unable to flex it. A 57-year-old female nurse had undergone injection of 40 mg of TA and 1 mL of 1% lidocaine solution into her thumb twice at a 2-month interval. Two months after the second injection, she was unable to flex it...
September 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28750969/a-case-study-utilizing-myofascial-release-acupressure-and-trigger-point-therapy-to-treat-bilateral-stringhalt-in-a-12%C3%A2-year-old-akhal-teke-horse
#11
Tammy Brockman
"Stringhalt" is a horse condition that causes one or both hind legs to spasm when walking, trotting or backing. The condition is thought to be related to a neurological cause from either plant toxicity or peripheral nerve injury. The prognosis is poor and the horse's performance and quality of life can be affected. Treatment has included surgically cutting the digital extensors with varied results. The objective of the study is to utilize soft tissue release via acupressure, trigger point and myofascial release to decrease symptoms of stringhalt...
July 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28742053/submillimeter-ionoacoustic-range-determination-for-protons-in-water-at-a-clinical-synchrocyclotron
#12
Sebastian Lehrack, Walter Assmann, Damien Bertrand, Sebastien Henrotin, Joel Herault, Vincent Heymans, Francois Vander Stappen, Peter G Thirolf, Marie Vidal, Jarno Van de Walle, Katia Parodi
Proton ranges in water between 145 MeV to 227 MeV initial energy have been measured at a clinical superconducting synchrocyclotron using the acoustic signal induced by the ion dose deposition (ionoacoustic effect). Detection of ultrasound waves was performed by a very sensitive hydrophone and signals were stored in a digital oscilloscope triggered by secondary prompt gammas. The ionoacoustic range measurements were compared to existing range data from a calibrated range detector setup on-site and agreement of better than 1 mm was found at a Bragg peak dose of about 10 Gy for 220 MeV initial proton energy, compatible with the experimental errors...
August 18, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28732159/remote-single-molecule-switching-identification-and-nanoengineering-of-hot-electron-induced-tautomerization
#13
Jens Kügel, Markus Leisegang, Markus Böhme, Andreas Krönlein, Aimee Sixta, Matthias Bode
Molecular electronics where single molecules perform basic functionalities of digital circuits is a fascinating concept that one day may augment or even replace nowadays semiconductor technologies. The tautomerization of molecules, that is, the bistable functional position of hydrogen protons within an organic frame, has recently been intensively discussed as a potential avenue toward nanoscale switches. It has been shown that tautomerization can be triggered locally or nonlocally, that is, by a scanning tunneling microscope (STM) tip positioned directly above or in close vicinity to the molecule...
July 26, 2017: Nano Letters
https://www.readbyqxmd.com/read/28727203/the-association-between-acute-mental-stress-and-abnormal-left-atrial-electrophysiology
#14
Wesley T O'Neal, Muhammad Hammadah, Pratik B Sandesara, Zakaria Almuwaqqat, Ayman Samman-Tahhan, Mohamad M Gafeer, Naser Abdelhadi, Kobina Wilmot, Ibhar Al Mheid, Douglas J Bremner, Michael Kutner, Elsayed Z Soliman, Amit J Shah, Arshed A Quyyumi, Viola Vaccarino
BACKGROUND: Acute stress may trigger atrial fibrillation (AF), but the underlying mechanisms are unclear. We examined if acute mental stress results in abnormal left atrial electrophysiology as detected by more negative deflection of P-wave terminal force in lead V1 (PTFV1 ), a well-known marker of AF risk. METHODS AND RESULTS: We examined this hypothesis in 422 patients (mean age = 56 ± 10 years; 61% men; 44% white) with stable coronary heart disease who underwent mental (speech task) stress testing...
July 20, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28720008/a-cadaveric-study-of-the-thread-trigger-finger-release-the-first-annular-pulley-transection-through-thread-transecting-technique
#15
Danqing Guo, Danzhu Guo, Joseph Guo, Logan C McCool, Brionn Tonkin
BACKGROUND: After the thread transecting technique was successfully applied for the thread carpal tunnel release, we researched using the same technique in the thread trigger finger release (TTFR). This study was designed to test the operational feasibility of the TTFR on cadavers and verify the limits of division on the first annular (A1) pulley to ensure a complete trigger finger release with minimal iatrogenic injuries. METHODS: The procedure of TTFR was performed on 14 fingers and 4 thumbs of 4 unembalmed cadaveric hands...
March 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28709917/what-triggers-in-trigger-finger-the-flexor-tendons-at-the-flexor-digitorum-superficialis-bifurcation
#16
X L Chuang, C C Ooi, S T Chin, M A Png, S K Wong, S C Tay, D A McGrouther
To define the role of the flexor tendons in trigger finger, a high-resolution ultrasound examination was performed in 20 trigger fingers and 20 normal contralateral digits in three digital postures: full extension, mid-flexion and near-full flexion. Precise measurements of diameter and cross-sectional area of the combined tendon mass were recorded at five clearly defined locations: summit of the metacarpal head, proximal lip of the proximal phalanx (PP) and at 1/8, 1/4 and 1/2 length of the PP. In the normal tendons, there was an anatomical thickening, not previously appreciated at 1/4 length PP, in the region of the FDS bifurcation...
October 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28691083/sub-100-nm-metafluorophores-with-digitally-tunable-optical-properties-self-assembled-from-dna
#17
Johannes B Woehrstein, Maximilian T Strauss, Luvena L Ong, Bryan Wei, David Y Zhang, Ralf Jungmann, Peng Yin
Fluorescence microscopy allows specific target detection down to the level of single molecules and has become an enabling tool in biological research. To transduce the biological information to an imageable signal, we have developed a variety of fluorescent probes, such as organic dyes or fluorescent proteins with different colors. Despite their success, a limitation on constructing small fluorescent probes is the lack of a general framework to achieve precise and programmable control of critical optical properties, such as color and brightness...
June 2017: Science Advances
https://www.readbyqxmd.com/read/28686120/coincidence-or-complication-a-systematic-review-of-trigger-digit-after-carpal-tunnel-release
#18
Fu-Yu Lin, Chao-I Wu, Hsu-Tang Cheng
BACKGROUND: Carpal tunnel syndrome (CTS) and trigger digits are among the most common nontraumatic hand disorders treated by plastic surgeons. The onset of trigger digits after carpal tunnel release (CTR) has been inconsistently reported. This systematic review assessed the prevalence of trigger digits development in patients after CTR surgery. METHODS: We searched the MEDLINE, EMBASE and SCOPUS databases for papers published between January 1966 and August 2016...
July 7, 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28682885/incidence-of-trigger-digits-following-carpal-tunnel-release-a-nationwide-population-based-retrospective-cohort-study
#19
Fu-Yu Lin, Oscar J Manrique, Cheng-Li Lin, Hsu-Tang Cheng
The onset of trigger digits after carpal tunnel release (CTR) have been reported inconsistently across different studies. The aim of this study is to assess the incidence of trigger digits after CTR using nationwide population cohort data.We conducted a retrospective cohort study using the Longitudinal Health Insurance Database 2000 (LHID2000) from the National Health Insurance Database (NHIRD) in Taiwan. The LHID2000 contained 1 million beneficiaries randomly selected from the year 2000 Registry for Beneficiaries in NHIRD...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28680421/an-emm5-group-a-streptococcal-outbreak-among-workers-in-a-factory-manufacturing-telephone-accessories
#20
Mingliang Chen, Wenqing Wang, Lihong Tu, Yaxu Zheng, Hao Pan, Gangyi Wang, Yanxin Chen, Xi Zhang, Linying Zhu, Jian Chen, Min Chen
Ranked among the top10 infectious causes of death worldwide, group A Streptococcus (GAS) causes small- and large-scale outbreaks, depending on the trigger as transmission of a GAS strain or expansion of predominant clones. In China, GAS infections other than scarlet fever are not notifiable. In Shanghai, an epidemiological investigation was initiated after two successive severe pneumonia cases with one death in a digital factory, from where outbreaks are less widely reported. The investigation was performed using emm typing, pulsed-field gel electrophoresis (PFGE) typing, superantigen profiling, and genome analysis...
2017: Frontiers in Microbiology
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