Do Kyun Kim, Kyoung Hoon Kim, Eun Ji Cho, Seoung-Je Joo, Jung-Min Chung, Byoung Yil Son, Jong Hwa Yum, Young-Man Kim, Hyun-Ju Kwon, Byung-Woo Kim, Tae Hoon Kim, Eun-Woo Lee
Multidrug resistance, especially multidrug efflux mechanisms that extrude structurally unrelated cytotoxic compounds from the cell by multidrug transporters, is a serious problem and one of the main reasons for the failure of therapeutic treatment of infections by pathogenic microorganisms as well as of cancer cells. Streptococcus mutans is considered one of the primary causative agents of dental caries and periodontal disease, which comprise the most common oral diseases. A fragment of chromosomal DNA from S...
March 2013: Journal of Microbiology and Biotechnology