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neonatology, premature infant

Sudhanshu Grover, Deeksha Katoch, Mangat R Dogra, Praveen Kumar
High quality perinatal-neonatal care can prevent severe Retinopathy of Prematurity (ROP) in most cases. Preterm infants who do develop retinopathy can also have good visual outcomes if screening and treatment are done timely. National Neonatology Forum published clinical practice guidelines for timely screening and treatment of ROP in neonatal care units in the country in 2010. It is also listed as one of the condition under Rashtriya Bal Swasthya Karyakram for early identification and early intervention, and is currently a focus area under the National Program for Control of Blindness...
November 7, 2016: Indian Pediatrics
Sourabh Dutta, Talkad Raghuveer, Anand Vinekar, Mangat Ram Dogra
Retinopathy of Prematurity (ROP) is a retinal vascular disease of the premature infant. There have been significant advances in the understanding of the pathogenesis, prevention, detection and treatment of severe ROP. In developed countries, all premature infants at risk for ROP are screened routinely based on national guidelines and treatment is prompt, resulting in good visual outcomes. Blindness from ROP is a rare event in these countries. However, there is an ongoing epidemic of ROP- induced blindness in India...
November 7, 2016: Indian Pediatrics
Jennifer L Fang, Christopher A Collura, Robert V Johnson, Garth F Asay, William A Carey, Douglas P Derleth, Tara R Lang, Beth L Kreofsky, Christopher E Colby
OBJECTIVE: To describe the Mayo Clinic experience with emergency video telemedicine consultations for high-risk newborn deliveries. PATIENTS AND METHODS: From March 26, 2013, through December 31, 2015, the Division of Neonatal Medicine offered newborn telemedicine consultations to 6 health system sites. A wireless tablet running secure video conferencing software was used by the local care teams. Descriptive data were collected on all consultations. After each telemedicine consult, a survey was sent to the neonatologist and referring provider to assess the technology, teamwork, and user satisfaction...
December 2016: Mayo Clinic Proceedings
Mandar S Joshi, Kelsey A Montgomery, Peter J Giannone, John A Bauer, Mina H Hanna
Preterm birth is associated with increased risks of morbidity and mortality along with increased healthcare costs. Advances in medicine have enhanced survival for preterm infants but the overall incidence of major morbidities has changed very little. Abnormal renal development is an important consequence of premature birth. Acute kidney injury (AKI) in the neonatal period is multifactorial and may increase lifetime risk of chronic kidney disease.Traditional biomarkers in newborns suffer from considerable confounders, limiting their use for early identification of AKI...
November 9, 2016: Pediatric Research
Colby L Day, Rita M Ryan
Despite the many advances in neonatology, bronchopulmonary dysplasia (BPD) continues to be a frustrating disease of prematurity. BPD is a disease which is defined oddly by its treatment rather than its pathophysiology, leading to frequently changing nomenclature which has widespread implications on our ability to both understand and follow the progression of BPD. As various treatment modalities for BPD were developed and a larger number of extremely preterm infants survived, the 'old' BPD based on lung injury from oxygen therapy and mechanical ventilation transitioned into a 'new' BPD focused more on the interruption of normal development...
September 28, 2016: Pediatric Research
Sandeep Grover, Zimei Zhou, Shamim Haji, Wassia Khaja, Kumar Sambhav, Merrill Stass-Isern, K V Chalam
PURPOSE: To evaluate the intraocular pressure (IOP) and central corneal thickness (CCT) in premature low birth weight (LBW) infants and their correlation with gestational age (GA). METHODS: IOP and CCT were measured in premature LBW infants (defined as a birth weight ≤ 1,500 g or birth GA ≤ 30 weeks) admitted to the neonatal intensive care unit at the University of Florida Division of Neonatology, UF Health Jacksonville. RESULTS: Ninety eyes of 45 premature LBW infants with mean birth GA of 28...
September 1, 2016: Journal of Pediatric Ophthalmology and Strabismus
Nilüfer Güzoğlu, Ümit Ayşe Tandircioğlu, Didem Aliefendioğlu
BACKGROUND/AIM: Prematurity is a significant risk factor for developing unconjugated hyperbilirubinemia. This study investigated the current approach to managing hyperbilirubinemia in preterm newborns in Turkey. MATERIALS AND METHODS: A study-specific questionnaire on the management of jaundice in preterm infants was sent to 100 level III neonatal intensive care units in Turkey. RESULTS: Responses were obtained from 84 centers from all regions of Turkey...
2016: Turkish Journal of Medical Sciences
Marie-Josée Martel, Isabelle Milette, Linda Bell, Denise St-Cyr Tribble, Antoine Payot
BACKGROUND: Parents and their preterm infants (born between 32-37 weeks of gestation) are often overlooked by the healthcare system. And very little attention is given to the relationship parents develop with their infants in the neonatal unit (NNU). Specifically, very few studies focused on fathers and how they establish a relationship with their infants. However, we know that the father-infant relationship is extremely important for their future social development and more. PURPOSE: This article presents the results of a qualitative study of the establishment of the father-premature infant relationship in an NNU...
August 5, 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
Claudia Reinheimer, Volkhard A J Kempf, Boris E Wittekindt, Antje Allendorf, Thomas A Wichelhaus, Michael Hogardt, Rolf L Schlößer, Doris Fischer
BACKGROUND: Infections by group B streptococci (GBS), e.g. Streptococcus agalactiae, presenting as early-onset disease (EOD) or late-onset disease (LOD), are leading causes of severe infections in newborn and premature patients. Although screening and intra partum antibiotic prophylaxis are frequently performed, vertically transmitted GBS remain a challenge for pediatrics. AIMS: In order to prevent or reduce potential life-threatening events, this study retrospectively investigated epidemiological, microbiological and clinical aspects of infants admitted to the Division of Neonatology at the Department of Pediatrics at the University Hospital Frankfurt, Germany (UHF)...
July 29, 2016: Early Human Development
Ravi Mangal Patel, Erin K Meyer, John A Widness
Red blood cell (RBC) transfusion is a common and lifesaving therapy for anemic neonates and infants, particularly among those born prematurely or undergoing surgery. However, evidence-based indications for when to administer RBCs and adverse effects of RBC transfusion on important outcomes including necrotizing enterocolitis, survival, and long-term neurodevelopmental impairment remain uncertain. In addition, blood-banking practices for preterm and term neonates and infants have been largely developed using studies from older children and adults...
October 2016: Transfusion Medicine Reviews
Dawid Szpecht, Marta Szymankiewicz, Irmina Nowak, Janusz Gadzinowski
INTRODUCTION: Intraventricular hemorrhage (IVH) affects 15-20 % of babies born before 32 weeks of pregnancy. A lot of risk factors of developing IVH are known. The making appropriate recommendations for dealing with infant born less than 32 weeks of gestation aimed at reducing the incidence of IVH is still needed. The study aim was to determine the incidence and analyze risk factors of IVH stage 3 and 4 in infants born before 32 + 0 weeks of pregnancy. METHODS: The retrospective analysis of 267 preterm babies (24 to 32 weeks of gestation) hospitalized in 2011-2013 at Department of Neonatology, Poznan University of Medical Sciences was performed...
August 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Florbela Neto, Ana Paula França, Sandra Cruz
UNLABELLED: Theme: Transition of care. INTRODUCTION: Oral feeding is one of the hardest steps for premature infants after respiratory independence and is a challenge for nurses in neonatology. OBJECTIVES: To know the characteristics of preterm infants, essential for oral feeding; to know the nurses' opinion on nursing interventions, that promote the transition of gavage feeding for oral feeding in preterm infants. METHODS: An exploratory, descriptive study with a qualitative approach was used...
May 9, 2016: Nursing Children and Young People
Leilei Wang, Jing Zhang, Jiejin Gao, Yan Qian, Ya Ling
Purpose. To retrospectively study the effect of fish oil-based lipid emulsion and soybean oil-based lipid emulsion on cholestasis associated with long-term parenteral nutrition in premature infants. Methods. Soybean oil-based lipid emulsion and fish oil-based lipid emulsion had been applied in our neonatology department clinically between 2010 and 2014. There were 61 qualified premature infants included in this study and divided into two groups. Soybean oil group was made up of 32 premature infants, while fish oil group was made up of 29 premature infants...
2016: Gastroenterology Research and Practice
Isabella Panfoli, Michela Cassanello, Matteo Bruschettini, Marina Colella, Roberto Cerone, Silvia Ravera, Daniela Calzia, Giovanni Candiano, Luca Ramenghi
Our preliminary data show high levels of adenosine in the blood of very low birth weight (VLBW) infants, positively correlating to their prematurity (i.e. body weight class). This prompted us to look for a mechanism promoting such impressive adenosine increase. We hypothesized a correlation with oxygen challenge. In fact, it is recognized that either oxygen lack or its excess contribute to the pathogenesis of the injuries of prematurity, such as retinopathy (ROP) and periventricular white matter lesions (PWMI)...
May 2016: Medical Hypotheses
Sidharth Mahapatra, Brian Scottoline
Pulmonary interstitial emphysema (PIE) is a familiar complication of mechanical ventilation in premature infants. Its most severe form, marked by life-threatening respiratory and cardiovascular compromise, is a particularly vexing problem in neonatology. Treatment modalities rely on decubitus positioning and reduction of mean airway pressure, but refractory PIE is unresponsive to these maneuvers. Other options such as selective unilateral bronchial intubation, balloon catheter bronchial occlusion, selective lung volume reduction, and mechanical decompression each have clear limitations...
December 2016: Journal of Maternal-fetal & Neonatal Medicine
Julia Kuligowski, Marwa R El-Zahry, Ángel Sánchez-Illana, Guillermo Quintás, Máximo Vento, Bernhard Lendl
Biothiols play an essential role in a number of biological processes in living organisms including detoxification and metabolism. Fetal to neonatal transition poses a pro-oxidant threat for newborn infants, especially those born prematurely. A reliable and rapid tool for the direct determination of thiols in small volume whole blood (WB) samples would be desirable for its application in clinical practice. This study shows the feasibility of Surface Enhanced Raman Spectroscopy (SERS) using a silver colloid prepared by reduction of silver nitrate using hydroxylamine, as the SERS substrate for the quantification of thiols in WB samples after a simple precipitation step for protein removal...
April 7, 2016: Analyst
P C Niz Xavier, P Gonçalves Vieira, T de Souza Arantes, M Yano, L V Martinelli Tavares, A M Duarte Miglioli, C S Martinbianco Figueiredo, A Sousa Martins, D Bastista Palhares
AIM: To study the frequency of congenital cytomegalovirus (CMV) infection in newborns admitted to the Division of Neonatology, using nested polymerase chain reaction (PCR) and DNA to detect differences in blood and urine specimens. METHODS: The study was carried out for eight months. Newborns (n = 520) hospitalized in five hospitals in Campo Grande, Mato Grosso do Sul, Brazil, were checked for CMV by analysing blood and urine samples. RESULTS: Cytomegalovirus was PCR positive in 13 urine and 10 blood samples...
May 7, 2015: West Indian Medical Journal
K Wiedemann, C Schmid, H Hamm, J Wirbelauer
INTRODUCTION: Staphylococcal scalded skin syndrome (SSSS) was often endemic in the past but is nowadays rare. The hematogeneous spread of exfoliative toxins A (ETA) or B (ETB) produced by specific Staphylococcus aureus strains causes a scald-like eruption with disseminated bullous lesions. CASE REPORT: A perioral impetigo lesion occurred on day 14 of life in a preterm male infant (1,065 g, 30 weeks of gestational age). Empiric antibiotic therapy with cefotaxime and vancomycin was given for 6 days and led to complete resolution...
February 2016: Zeitschrift Für Geburtshilfe und Neonatologie
Rosa Geurtzen, Arno Fj van Heijst, Srinivasarao Babarao, Eleanor Molloy, Jos Mt Draaisma, Marije Hogeveen
UNLABELLED: There is no international consensus on content and process regarding antenatal counseling in extreme prematurity. The need for adequate training is increasingly recognized. This descriptive study evaluates current practice in antenatal counseling amongst European trainees using an online survey. Focusing on the process, the majority of respondents did not have a medical consensus guideline. Seven percent of the trainees received some formal training. Focusing on the content, about half of the subjects did not mention any statistics about mortality...
December 2016: Journal of Maternal-fetal & Neonatal Medicine
Patricia Mena Nannig, M Paz Cubillos Celis, Claudia Toro Jara, Carlos Zuñiga Vergara
INTRODUCTION: The use of greater amounts of protein and energy during the first week of life is associated with hypophosphataemia in extreme preterm babies. The lowest phosphorus levels are described in intrauterine growth restricted (IUGR) babies. OBJECTIVES: To describe biochemistry levels in cord blood plasma in extreme premature, adequate and small for gestational age babies (AGA/SGA) and their relationship with plasma calcium and phosphorus levels during the first week of life...
July 2016: Revista Chilena de Pediatría
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