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Microorganism, metal nanoparticles

Matheus Aparecido Dos Santos Ramos, Patrícia Bento Da Silva, Larissa Spósito, Luciani Gaspar De Toledo, Bruna Vidal Bonifácio, Camila Fernanda Rodero, Karen Cristina Dos Santos, Marlus Chorilli, Taís Maria Bauab
Since the dawn of civilization, it has been understood that pathogenic microorganisms cause infectious conditions in humans, which at times, may prove fatal. Among the different virulent properties of microorganisms is their ability to form biofilms, which has been directly related to the development of chronic infections with increased disease severity. A problem in the elimination of such complex structures (biofilms) is resistance to the drugs that are currently used in clinical practice, and therefore, it becomes imperative to search for new compounds that have anti-biofilm activity...
2018: International Journal of Nanomedicine
Muhammad Junaid Afzal, Erum Pervaiz, Sarah Farrukh, Tahir Ahmed, Zhang Bingxue, Minghui Yang
Highly integrated nanocomposite of Graphene oxide (GO) and its derivatives with metal oxides is essential for enhanced performance for various applications. Tuning the morphology is an important aspect during nanomaterials synthesis; this has an amplifying influence upon physicochemical properties of advanced functional materials. In this research work, Graphene oxide/TiO2 nanotube composites have been successfully synthesized via alkaline hydrothermal treatment method by augmenting GO layers with two different phases of TiO2 (anatase and rutile) nanoparticles, followed by the hydrothermal treatment that also have caused reduction of GO to reduced GO (RGO)...
March 1, 2018: Environmental Technology
Humberto Palza, Mauricio Nuñez, Roberto Bastías, Katherine Delgado
Copper and its alloys are recognized as effective antimicrobial surface materials at the laboratory scale as well as in clinical trials. Copper has been used in the healthcare setting to reduce environmental contamination and thus prevent healthcare-associated infections, complementing traditional protocols. The addition of copper nanoparticles to polymer/plastic matrices can also produce antimicrobial materials as confirmed under laboratory conditions. However, there is a lack of studies validating the antimicrobial behavior of these nanocomposite materials in clinical trials...
February 19, 2018: International Journal of Antimicrobial Agents
Lidiane Patrícia Gonçalves, Alejandro Miñán, Guillermo Benítez, Mónica Fernández Lorenzo de Mele, María Elena Vela, Patricia L Schilardi, Elias Paiva Ferreira-Neto, Júlia Cristina Noveletto, Wagner Rafael Correr, Ubirajara Pereira Rodrigues-Filho
Medical device-related infections represent a major healthcare complication, resulting in potential risks for the patient. Antimicrobial materials comprise an attractive strategy against bacterial colonization and biofilm proliferation. However, in most cases these materials are only bacteriostatic or bactericidal, and consequently they must be used in combination with other antimicrobials in order to reach the eradication condition (no viable microorganisms). In this study, a straightforward and robust antibacterial coating based on Phosphotungstate Ormosil doped with core-shell (SiO2@TiO2) was developed using sol-gel process, chemical tempering, and Ag nanoparticle photoassisted synthesis (POrs-CS-Ag)...
December 26, 2017: Colloids and Surfaces. B, Biointerfaces
Xiaoming Ma, Peng Liu, Yuyang Tian, Guangshan Zhu, Ping Yang, Ge Wang, Lin Yang
A unique mineralized cell-based functional platform with biogenic intracellular hydroxyapatite nanoscaffolds (nHAP@yeasts) has been intelligently constructed using a biomimetic mineralization approach. Such a platform not only preserves the nature and functions of cells but also possesses intracellular nanoscaffolds, which endow the mineralized cells with novel functions in biological and nanotechnological applications. Benefiting from their unique organism shell and inorganic core, the nHAP@yeasts are biocompatible and have a large loading capacity for drugs...
February 15, 2018: Nanoscale
Ke Luo, Samuel Jung, Kyu-Hwan Park, Young-Rok Kim
Microbial biosynthesis of metal nanoparticles has been extensively studied for the applications in biomedical sciences and engineering. However, the mechanism for their synthesis through microorganism is not completely understood. In this study, several culture media were investigated for their roles in the microbial biosynthesis of silver nanoparticles (AgNPs). The size and morphology of the synthesized AgNPs were analyzed by UV-Vis spectroscopy, FT-IR, TEM, and DLS. The results demonstrated that nutrient broth (NB) and Mueller-Hinton broth (MHB) among tested media effectively reduced silver ions to form AgNPs with different particle size and shape...
January 11, 2018: Journal of Agricultural and Food Chemistry
Tuğçe Yurtluk, Fikriye Alev Akçay, Ayşe Avcı
Biosynthesis of silver nanoparticles (AgNPs) using microorganisms is an important application of nano-biotechnology and green chemistry because of interest by pharmaceutical and food manufacturers. In this study, biosynthesis of AgNPs by a novel Bacillus strain isolated from a soil sample from Sakarya district in Turkey was investigated. Biosynthesis was performed using cell-free supernatant of the bacterium following 24 h growth. Effects of varying AgNO3 concentration (1-10 mM), pH (5-10), and temperature (30-40°C) on the synthesis of AgNPs were determined...
January 9, 2018: Preparative Biochemistry & Biotechnology
Aharon Gedanken, Nina Perkas, Ilana Perelshtein, Anat Lipovsky
The review, reports on the functionalization of textiles for the treatment of wounds and skin diseases such as acne. In view of the growing demand for high-quality textiles, much research is focused on the creation of antimicrobial finishings for fabrics, in order to protect customers from pathogenic or odor-generating microorganisms. We present coatings from inorganic, organic and biochemical nanoparticles (NPs) on surfaces that impart the ability to kill bacteria, avoid biofilm formation and speed up the recovery of wounds...
December 29, 2017: Current Medicinal Chemistry
Marin Vincent, Raphaël E Duval, Philippe Hartemann, Marc Engels-Deutsch
With the emergence of antibiotic resistance, the interest for antimicrobial agents has recently increased again in public health. Copper was recognized in 2008 by the United States Environmental Protection Agency (EPA) as the first metallic antimicrobial agent. This led to many investigations of the various properties of copper as an antibacterial, antifungal and antiviral agent. This review summarizes the latest findings about "contact killing", the mechanism of action of copper nanoparticles and the different ways microorganisms develop resistance to copper...
December 27, 2017: Journal of Applied Microbiology
Jiangbing Xu, Xiaosan Luo, Yanling Wang, Youzhi Feng
The wide spread of nanoparticles (NPs) has caused tremendous concerns on agricultural ecosystem. Some metallic NPs, such as zinc oxide (ZnO), can be utilized as a nano-fertilizer when used at optimal doses. However, little is known about the responses of plant development and concomitant soil bacteria community to ZnO NPs. The present pot experiment studied the impacts of different doses of ZnO NPs and bulk ZnO (0, 1, 10, 100 mg ZnO/kg), on the growth of lettuce (Lactuca sativa L.) and the associated rhizospheric soil bacterial community...
December 14, 2017: Environmental Science and Pollution Research International
S Mahadevan, S Vijayakumar, P Arulmozhi
In the present study deals with the green synthesis of silver nano particles from methanolic leaf extracts of Atalantia monophylla. The synthesized nano-particles are characterized by UV-vis spectroscopy, PL, FTIR, XRD, SEM with EDAX and TEM. The nano-particles are indicated in absorption peak at 404 nm in the absorption spectrum. Further micro graphical analysis confirmed the average size was estimated about 35 nm and SEAD pattern authorized well crystalline materials. The FTIR studies help to confirm the functional group of synthesized silver nano particles...
December 2017: Microbial Pathogenesis
Su-Eon Jin, Woochul Hwang, Hyo Jung Lee, Hyo-Eon Jin
Metal oxide (MO) nanoparticles have been studied as nano-antibiotics due to their antimicrobial activities even in antibiotic-resistant microorganisms. We hypothesized that a hybrid system of dual UV irradiation and MO nanoparticles would have enhanced antimicrobial activities compared with UV or MO nanoparticles alone. In this study, nanoparticles of ZnO, ZnTiO3, MgO, and CuO were selected as model nanoparticles. A dual UV collimated beam device of UV-A and UV-C was developed depending upon the lamp divided by coating...
2017: International Journal of Nanomedicine
Pramod C Mane, Ravindra D Chaudhari, Manish D Shinde, Deepali D Kadam, Chung Kil Song, Dinesh P Amalnerkar, Haiwon Lee
Dialyzed natural polymer, fibroin, from Bombyx mori was used to synthesize biocompatible silver and gold nanoparticles in-situ in dispersion form. The films of pure fibroin (PF), fibroin-silver nanocomposite (FSNC) and fibroin-gold nanocomposite (FGNC) were fabricated by drop casting method. The characterization of the resultant dispersion and films was performed by visual color change, UV-Vis spectroscopy and atomic force microscopy. The dispersions of PF, FSNC and FGNC were tested for antibacterial activity against E...
November 14, 2017: Scientific Reports
Rafael G Lacalle, María T Gómez-Sagasti, Unai Artetxe, Carlos Garbisu, José M Becerril
Contaminated soils are frequently characterized by the simultaneous presence of organic and inorganic contaminants, as well as a poor biological and nutritional status. Rhizoremediation, the combined use of phytoremediation and bioremediation, has been proposed as a Gentle Remediation Option to rehabilitate multi-contaminated soils. Recently, newer techniques, such as the application of metallic nanoparticles, are being deployed in an attempt to improve traditional remediation options. In order to implement a phytomanagement strategy on calcareous alkaline peri-urban soils simultaneously contaminated with several metals and diesel, we evaluated the effectiveness of Brassica napus L...
November 10, 2017: Science of the Total Environment
Sara Shoeibi, Paul Mozdziak, Afsaneh Golkar-Narenji
Selenium binds some enzymes such as glutathione peroxidase and thioredoxin reductase, which may be activated in biological infections and oxidative stress. Chemical and physical methods for synthesizing nanoparticles, apart from being expensive, have their own particular risks. However, nanoparticle synthesis through green chemistry is a safe procedure that different biological sources such as bacteria, fungi, yeasts, algae and plants can be the catalyst bed for processing. Synthesis of selenium nanoparticles (SeNPs) by macro/microorganisms causes variation in morphology and shape of the particles is due to diversity of reduction enzymes in organisms...
November 9, 2017: Topics in Current Chemistry (Journal)
Xuemei Chen, Seockmo Ku, Justin A Weibel, Eduardo Ximenes, Xingya Liu, Michael Ladisch, Suresh V Garimella
The antimicrobial action of porous CuO microspheres (μCuO), Ag nanoparticles (nAg), and bimetallic porous CuO microspheres decorated with Ag nanoparticles (μCuO/nAg) was evaluated against surrogate microorganisms representative of pathogens commonly implicated in foodborne and healthcare-associated human infections. This work addressed the Gram-negative bacteria E. coli (Escherichia coli O157:H7-GFP B6-914), Salmonella (Salmonella enterica serovar enteritidis phage-type PT21), and the Gram-positive bacteria Listeria (Listeria innocua), as well as environmental microorganisms derived from local river water...
November 1, 2017: ACS Applied Materials & Interfaces
Patricia Jayshree Jacob, Mas Jaffri Masarudin, Mohd Zobir Hussein, Raha Abdul Rahim
BACKGROUND: Iron based ferromagnetic nanoparticles (IONP) have found a wide range of application in microelectronics, chemotherapeutic cell targeting, and as contrast enhancers in MRI. As such, the design of well-defined monodisperse IONPs is crucial to ensure effectiveness in these applications. Although these nanostructures are currently manufactured using chemical and physical processes, these methods are not environmentally conducive and weigh heavily on energy and outlays. Certain microorganisms have the innate ability to reduce metallic ions in aqueous solution and generate nano-sized IONP's with narrow size distribution...
October 11, 2017: Microbial Cell Factories
Biplab Sarkar, Akshay Vishnu Daware, Priya Gupta, Kishore Kumar Krishnani, Sunandan Baruah, Surajit Bhattacharjee
Water pollution is a serious challenge to the public health. Among different forms of aquatic pollutants, chemical and biological agents create paramount threat to water quality when the safety standards are surpassed. There are many conventional remediatory strategies that are practiced such as resin-based exchanger and activated charcoal/carbon andreverse osmosis. Newer technologies using plants, microorganisms, genetic engineering, and enzyme-based approaches are also proposed for aquatic pollution management...
November 2017: Environmental Science and Pollution Research International
P V Mohanan, V G Reshma, S Syama, S Sruthi, S C Reshma, N S Remya
The urge for the development and manufacture of new and effective antimicrobial agents are particularly demanding especially in the present scenario of emerging multiple drug resistant microorganisms. A promising initiative would be to converge nanotechnology to develop novel strategies for antimicrobial treatment. The distinct nano scale properties confer impressive antimicrobial capabilities to nanomaterials that could be exploited. Nanotechnology particularly modulates the physicochemical properties of metals and metal oxides rendering it suitable for various applications compared to their bulk counterparts...
September 25, 2017: Current Drug Metabolism
Cheryl S Rosenfeld
The gut microbiome consists of over 10(3)-10(4) microorganism inhabitants that together possess 150 times more genes that the human genome and thus should be considered an "organ" in of itself. Such communities of bacteria are in dynamic flux and susceptible to changes in host environment and body condition. In turn, gut microbiome disturbances can affect health status of the host. Gut dysbiosis might result in obesity, diabetes, gastrointestinal, immunological, and neurobehavioral disorders. Such host diseases can originate due to shifts in microbiota favoring more pathogenic species that produce various virulence factors, such as lipopolysaccharide...
2017: Frontiers in Cellular and Infection Microbiology
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