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https://www.readbyqxmd.com/read/25298128/postoperative-hypocaloric-peripheral-parenteral-nutrition-with-branched-chain-enriched-amino-acids-provides-no-better-clinical-advantage-than-fluid-management-in-nonmalnourished-colorectal-cancer-patients
#1
Hsiu-Hua Huang, Pi-Chuan Wu, Shiu-Ping Kang, Jui-Ho Wang, Chien-Wei Hsu, Leh-Chii Chwang, Sue-Joan Chang
To assess clinical efficacy of using postoperative branched-chain amino acids (BCAAs)-enriched nutritional support in lower gastrointestinal cancer patients, we conducted a retrospective observational study comparing this regimen with traditional fluid management. Sixty-one eligible colorectal cancer patients consecutively admitted in the Colorectal Surgery Ward to receive postoperative hypocaloric peripheral parenteral nutrition (HPPN) were categorized into dextrose-only control group (n = 20), dextrose plus low-dose BCAA fat group (n = 20), and dextrose plus high-dose BCAA fat group (n = 21)...
2014: Nutrition and Cancer
https://www.readbyqxmd.com/read/21160817/hypocaloric-peripheral-parenteral-nutrition-with-lipid-emulsion-in-postoperative-gastrointestinal-cancer-patients
#2
Chien-Yu Lu, Hung-Yi Chuang, Fang-Jung Yu, Li-Chu Sun, Ying-Ling Shih, Fang-Ming Chen, Jan-Sing Hsieh, Jaw-Yuan Wang
AIM: To investigate the use of lipid emulsion substituting for glucose in postoperative hypocaloric peripheral parenteral nutrition (HPPN). METHODS: This prospective, randomized study was conducted on 20 postoperative gastrointestinal cancer patients. They were randomized and equally divided into interventional group and control group, and both were administered isocaloric and isonitrogenous diets with for lipid emulsion substituting for partial glucose loads in the interventional group...
January 15, 2010: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/16843906/study-of-hypocaloric-peripheral-parenteral-nutrition-in-postoperative-patients-european-project
#3
F J Jiménez Jiménez, C O Leyba, L M Jiménez Jiménez, M S Valdecasas, J G Montero
The objective of this study is to ascertain whether or not the supply of a low-calorie amino acids (AA) parenteral solution is useful in postoperative patients, by assessing a series of parameters that indicate nutritional status. 75 postoperative patients who met at least 2 of the 3 criteria: 1) albumin less than 3 g/dl; 2)prealbumin less than 21 mg/dl; 3) body weight less than 95% of ideal weight, were studied. Patients were divided into 4 groups: control group, 15 patients receiving conventional infusion therapy; group I, 20 patients receiving glucose + AA; group II, 20 patients receiving glycerol + AA; and group III, 20 patients receiving sorbitol-xylitol + AA...
April 1995: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/16831758/does-peripheral-hypocaloric-parenteral-nutrition-benefit-the-postoperative-patient-results-of-a-multicentric-randomized-trial
#4
J Figueras-Felip, A Rafecas-Renau, A Sitges-Serra, P Puig-Gris, F Pi-Siques, J Colomer, A Bianchi-Cardona
To study the potential benefits of hypocaloric peripheral parenteral nutrition (HPPN) in medium to high risk surgical patients we compared this regimen with standard fluid therapy during the postoperative period. Seventy patients were randomised to receive HPPN, consisting of 1 g of amino acids and 2 g of polyols (sorbitol and xylitol) per Kg per day (n = 41), or 1500 ml of 5% glucose and 1500 ml of saline (n = 29). There were no differences in length of hospital stay, postoperative complications or weight loss between the two groups...
May 1986: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/8766613/-amino-acid-pattern-variation-in-animals-after-the-administration-of-hypocaloric-peripheral-parenteral-nutrition
#5
COMPARATIVE STUDY
M L de la Hoz Riesco, M Prieto Prado, J García Vielba, F García Díez, E García Arumi, J M Culebras Fernández
The pattern of intracellular aminoacids may be reproduced individually and is different for each illness. This study seeks to measure alterations in this pattern in rats after the administration of hypocaloric peripheral parenteral nutrition (HPPN), group B, for five days, by comparing them with rats subjected to conventional fluidtherapy, group A, for the same period. HPPN tolerance was good in all cases. Our results show a higher tendency to glyconeogenesis in group A, measured by a reduction in the glycogenic aminoacids especially alanine...
May 1996: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/8018755/-hypocaloric-peripheral-parenteral-nutrition-in-postoperative-patients-the-europan-project-ii
#6
COMPARATIVE STUDY
F J Jiménez Jiménez, C Ortiz Leyba, L Jiménez Jiménez, M S García Valdecasas
Hypocaloric peripheral parenteral nutrition (HPPN) appears to be indicated in patients in a situation of moderate malnutrition who are to undergo a short period of fasting following surgery. Our aim was to determine the utility of the contribution of parenteral solutions of amino acids (AA) with limited caloric supply in the post-surgical patient, using different nutritional evaluation parameters. We examined 75 post-surgical patients who met at least two of the three criteria established as malnutrition: 1) albumin < 3 g/dl; 2) pre-albumin < 21 mg/dl; 3) bodyweight of less than 95% of the ideal weight...
May 1994: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/3119481/improvement-of-the-nutritional-condition-with-hypocaloric-peripheral-parenteral-nutrition-hppn-in-the-immediate-postoperative-period-of-elective-abdominal-surgery
#7
RANDOMIZED CONTROLLED TRIAL
J M Culebras-Fernandez, M de la Hoz Riesco, C Villares Garcia, G Hurtado Fernandez-Llamazares, A Alonso Villalba
Thirty-one patients scheduled for elective surgery for non-malignant abdominal disease were randomized during the first five postoperative days to two different schedules. Group I received water, electrolytes and glucose. Group II received a standard solution containing crystalline amino acids (3.8 g/l), xylitol (25 g/l) and sorbitol (25 g/l), accounting for a total of 900 cal/day. Evaluation was made with clinical, anthropometric and biochemical parameters. Among others, the following significant differences were observed at the end of the study: retinol bound protein: in group I, 4...
October 1987: Infusionstherapie und Klinische Ernährung
https://www.readbyqxmd.com/read/3015693/prevalence-of-and-markers-for-the-attenuated-form-of-congenital-adrenal-hyperplasia-and-hyperprolactinemia-masquerading-as-polycystic-ovarian-disease
#8
F Benjamin, S Deutsch, H Saperstein, V L Seltzer
To determine the prevalence of the attenuated form of congenital adrenal hyperplasia (CAH) and hyperprolactinemia (HPPN) relative to polycystic ovarian disease (PCOD), 100 consecutive women presenting with the classic clinical features of PCOD were evaluated by basal hormonal profiles and subsequent adrenocorticotropic hormone (ACTH) stimulation tests. The study also sought biochemical markers for CAH other than ACTH stimulation. The prevalences were found to be as follows: PCOD, 65%; PCOD with HPPN, 9%; HPPN, 3%, end-organ hypersensitivity (EOH), 4%; homozygotic CAH, 4%; and heterozygotic CAH, 15%...
August 1986: Fertility and Sterility
https://www.readbyqxmd.com/read/1391107/-hypocaloric-peripheral-parenteral-nutrition-in-postoperative-patients-proyecto-europan
#9
COMPARATIVE STUDY
F J Jiménez Jiménez, C Ortiz Leyba
Hypocaloric peripheral parenteral nutrition (HPPN) appears to be indicated in patients with moderate malnutrition subjected to a short period of fasting following surgery. Our objective is to determine whether or not the intake of hypocaloric parenteral solutions containing aminoacid is useful in postsurgical patients, by means of a study of different nutritional evaluation parameters. A study was performed on 35 postsurgical patients who fulfilled at least 2 of the following criteria indicating malnutrition: 1) albumin levels less than 3 g/dl; 2) prealbumin levels less than 21 mg/; 3) body weight less than 95% of ideal weight...
July 1992: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/1127723/carcinogenic-effects-of-di-n-propylnitrosamine-beta-hydroxypropyl-n-propylnitrosamine-and-methyl-n-propylnitrosamine-on-sprague-dawlay-rats
#10
COMPARATIVE STUDY
G Reznik, U Mohr, F W Krüger
The carcinogenic effects of di-n-propylnitrosamine and its two related compounds, beta-hydroxypropyl-n-propylnitrosamine (HPPN) and methyl-n-propylnitrosamine (MPN), were tested in rats and compared. All three substances induced neoplasms in the nasal and paranasal cavities, esophagus, and liver. MPN treatment caused the highest tumor incidence in the esophagus, whereas HPPN induced the most hepatic tumors.
April 1975: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/163311/effect-of-beta-oxidized-nitrosamines-on-syrian-hamsters-iii-2-2-dihydroxydi-n-propylnitrosamine
#11
P Pour, F W Krüger, J Althoff, A Cardesa, U Mohr
2, 2-Dihydroxy-di-n-propylnitrosamine (DHPN), an assumed metabolite of di-n-propylnitrosamine (DPN), injected subcutaneously once weekly for life, was carcinogenic in Syrian hamsters. The main target organs were the respiratory tract, pancreas, liver, and kidneys. In the respiratory system the most affected segments were the nasal cavities and the lungs. Adenomas and adenocarcinomas, mostly of ductal origin, were induced in the pancreas. Liver neoplasms were hemangloendotheliomas, angiosarcomas, hepatocellular adenomas, cholangiomas, and cholangiocarcinomas...
January 1975: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/145753/transplacental-effect-of-nitrosamines-in-syrian-hamsters-iv-metabolites-of-dipropyl-and-dibutylnitrosamine
#12
J Althoff, C Grandjean, P Pour
The present investigations showed that assumed and established metabolites of dipropylnitrosamine and dibutylnitrosamine reach the Syrian hamster fetus after subcutaneous (s.c.) treatment of their mothers (at day 14 of gestation). The compounds [2-hydroxypropylpropylnitrosamine, HPPN; 2-oxopropylpropylnitrosamine, OPPN; methylpropylnitrosamine, MPN; N-nitrosobis(2-hydroxypropyl)amine, BHP; and 4-hydroxybutylbutylnitrosamine, HBBN] were still present in the examined tissue (maternal blood, placenta, fetus, amniotic fluid) 4--6 h after s...
November 18, 1977: Zeitschrift Für Krebsforschung und Klinische Onkologie. Cancer Research and Clinical Oncology
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