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Research Domain Criteria

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https://www.readbyqxmd.com/read/27927742/concordance-and-discordance-of-self-rated-and-researcher-measured-successful-aging-subtypes-and-associated-factors
#1
Danan Gu, Qiushi Feng, Jessica M Sautter, Fang Yang, Lei Ma, Zhihong Zhen
OBJECTIVES: To investigate subtypes of successful aging (SA) based on concordance and discordance between self-rated and researcher-defined measures and their associations with demographic, psychosocial, and life satisfaction factors. METHOD: We used multinomial logistic regression models to analyze 2013 cross-sectional survey data from 1,962 persons aged 65 and older in Shanghai that measured self-rated successful aging (SSA) with a single global assessment and researcher-defined successful aging (RSA) with a cumulative deficit index reflecting physical, physiological, cognitive, psychological, and social engagement domains...
December 7, 2016: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/27923496/neural-correlates-of-rdoc-reward-constructs-in-adolescents-with-diverse-psychiatric-symptoms-a-reward-flanker-task-pilot-study
#2
Kailyn A L Bradley, Julia A C Case, Rachel D Freed, Emily R Stern, Vilma Gabbay
BACKGROUND: There has been growing interest under the Research Domain Criteria initiative to investigate behavioral constructs and their underlying neural circuitry. Abnormalities in reward processes are salient across psychiatric conditions and may precede future psychopathology in youth. However, the neural circuitry underlying such deficits has not been well defined. Therefore, in this pilot, we studied youth with diverse psychiatric symptoms and examined the neural underpinnings of reward anticipation, attainment, and positive prediction error (PPE, unexpected reward gain)...
December 1, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27920349/factors-associated-with-physical-activity-in-latina-women-a-systematic-review
#3
Marlene Tovar, Janiece L Walker, Lynn Rew
The purpose of this systemic literature review is to unveil a greater understanding of Physical Activity in Latinas. We used PubMed and PsycInfo databases to search for articles published between 1991 and August 2016, examining physical activity and its correlates exclusively in adult Latinas. Only 21 primary studies met the inclusion criteria. Although physical activity derives from body movements in various domains, the leisure domain led the focus of research interest. The use of self-reports, cross-sectional design, and the ecological framework predominated...
December 5, 2016: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/27913990/sirukumab-a-potential-treatment-for-mood-disorders
#4
REVIEW
Aileen J Zhou, Yena Lee, Giacomo Salvadore, Benjamin Hsu, Trehani M Fonseka, Sidney H Kennedy, Roger S McIntyre
Convergent evidence indicates that abnormalities in the innate immune system may be pertinent to the pathogenesis, phenomenology, and possible treatment of several mental disorders. In keeping with this view, the targeting of interleukin-6 with the human monoclonal antibody sirukumab may represent a possible treatment and disease modification approach, for adults with brain-based disorders (e.g., major depressive disorder). A PubMed/Medline database search was performed using the following search terms: sirukumab; anti-IL-6; IL-6; major depressive disorder; inflammation...
December 2, 2016: Advances in Therapy
https://www.readbyqxmd.com/read/27912958/a-systematic-review-of-the-ayurvedic-medicinal-herb-bacopa-monnieri-in-child-and-adolescent-populations
#5
REVIEW
James D Kean, Luke A Downey, Con Stough
OBJECTIVES: Clinicians utilise critical research to advance their knowledge when prescribing standard and alternative therapies for developmental disorders. Recent research has reported that the traditional Ayurvedic medicine Bacopa monnieri may improve cognitive outcomes in adult populations; however, few studies have investigated its benefits in younger cohorts. The aim of the current review is to systematically assess and critically summarize clinical trial outcomes and safety of Bacopa and its effects on the cognition and behaviour in children and adolescents...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27904819/an-overview-of-compassionate-use-programs-in-the-european-union-member-states
#6
REVIEW
Gayathri Balasubramanian, Suman Morampudi, Pankdeep Chhabra, Arun Gowda, Behsad Zomorodi
The past decade witnessed rapid development of novel drugs and therapeutic biological agents. The marketing authorization for novel therapies is often time consuming and distressing for patients. Earlier clinical trials were the only way to access new drugs under development. However, not every patient meets the enrolment criteria, and participation is difficult for patients with life-threatening, long-lasting or seriously debilitating diseases like rare diseases. Early access programs like "Compassionate Use Program (CUP)" have generated alternative channels for such patients...
November 2016: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/27876165/application-of-research-domain-criteria-to-childhood-and-adolescent-impulsive-and-addictive-disorders-implications-for-treatment
#7
REVIEW
Sarah W Yip, Marc N Potenza
The Research Domain Criteria (RDoC) initiative provides a large-scale, dimensional framework for the integration of research findings across traditional diagnoses, with the long-term aim of improving existing psychiatric treatments. A neurodevelopmental perspective is essential to this endeavor. However, few papers synthesizing research findings across childhood and adolescent disorders exist. Here, we discuss how the RDoC framework may be applied to the study of childhood and adolescent impulsive and addictive disorders in order to improve neurodevelopmental understanding and to enhance treatment development...
November 9, 2016: Clinical Psychology Review
https://www.readbyqxmd.com/read/27875605/sustaining-family-physicians-in-urban-underserved-settings
#8
Anne Getzin, Bonnie L Bobot, Deborah Simpson
OBJECTIVE: Our objective was to identify factors that sustain family physicians practicing in Milwaukee's underserved urban areas. METHODS: Family physicians with clinical careers in Milwaukee's urban, underserved communities were identified and invited to participate in a 45-60 minute interview using a literature-based semi-structured protocol. Each interview was transcribed and de-identified prior to independent analysis using a grounded theory qualitative approach by two authors to yield sustaining themes...
November 2016: Family Medicine
https://www.readbyqxmd.com/read/27875416/comparison-of-structural-disease-burden-to-health-related-quality-of-life-scores-in-264-adult-spinal-deformity-patients-with-2-year-follow-up-novel-insights-into-drivers-of-disability
#9
Joshua Bakhsheshian, Justin K Scheer, Jeffrey L Gum, Lance Horner, Richard Hostin, Virginie Lafage, Shay Bess, Themistocles S Protopsaltis, Douglas C Burton, Malla Keefe, Robert A Hart, Gregory M Mundis, Christopher I Shaffrey, Frank Schwab, Justin S Smith, Christopher P Ames
STUDY DESIGN: This is a review of a prospective multicenter database. OBJECTIVE: To investigate the relationship between preoperative disability and sagittal deformity in patients with high Oswestry Disability Index (ODI) and no sagittal malalignment, or low ODI and high sagittal malalignment. SUMMARY OF BACKGROUND DATA: The relationship between ODI and sagittal malalignment varies between each adult spinal deformity (ASD) patient. METHODS: A prospective multicenter database of 365 patients with ASD undergoing surgical reconstruction was analyzed...
November 21, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27872347/toward-an-empirical-multidimensional-structure-of-anhedonia-reward-sensitivity-and-positive-emotionality-an-exploratory-factor-analytic-study
#10
Thomas M Olino, Dana L McMakin, Erika E Forbes
Positive emotionality, anhedonia, and reward sensitivity share motivational and experiential elements of approach motivation and pleasure. Earlier work has examined the interrelationships among these constructs from measures of extraversion. More recently, the Research Domain Criteria introduced the Positive Valence Systems as a primary dimension to better understand psychopathology. However, the suggested measures tapping this construct have not yet been integrated within the structural framework of personality, even at the level of self-report...
November 20, 2016: Assessment
https://www.readbyqxmd.com/read/27870978/towards-the-standardization-of-stem-cell-therapy-studies-for-ischemic-heart-diseases-bridging-the-gap-between-animal-models-and-the-clinical-setting
#11
REVIEW
Fábio Trindade, Adelino Leite-Moreira, João Ferreira-Martins, Rita Ferreira, Inês Falcão-Pires, Rui Vitorino
Today there is an increasing demand for heart transplantations for patients diagnosed with heart failure. Though, shortage of donors as well as the large number of ineligible patients hurdle such treatment option. This, in addition to the considerable number of transplant rejections, has driven the clinical research towards the field of regenerative medicine. Nonetheless, to date, several stem cell therapies tested in animal models fall by the wayside and when they meet the criteria to clinical trials, subjects often exhibit modest improvements...
November 14, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27869364/assessing-the-reliability-of-ecotoxicological-studies-an-overview-of-current-needs-and-approaches
#12
Cta Moermond, A Beasley, R Breton, M Junghans, R Laskowski, K Solomon, H Zahner
In general, reliable studies are well designed, performed, and enough details on study design and performance are reported to assess the study. For hazard and risk assessment in various legal frameworks, many different types of ecotoxicity studies need to be evaluated for reliability. These studies vary in study design, methodology, quality, and in the level of detail reported (e.g., reviews, peer-reviewed research papers, or industry-sponsored studies documented under Good Laboratory Practice (GLP) guidelines)...
November 21, 2016: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/27868438/a-standardized-review-of-smartphone-applications-to-promote-balance-for-older-adults
#13
Angelica Reyes, Pei Qin, Cary A Brown
BACKGROUND: Balance is one of the risk factors for falls in older adults. The use of smartphone applications (apps) related to health (mHealth) is increasing and, while there is potential for apps to be used as a self-managed balance intervention, many healthcare providers are concerned about the content and credibility of mHealth apps overall. PURPOSE: This study evaluates the quality of balance promoting apps and identifies strengths and areas of concern to assist healthcare providers in recommending these resources...
November 20, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27863803/research-domain-criteria-and-the-study-of-trauma-in-children-implications-for-assessment-and-treatment-research
#14
REVIEW
Carla Smith Stover, Brooks Keeshin
By definition, the Diagnostic and Statistical Manual (DSM) diagnosis of posttraumatic stress disorder (PTSD) requires exposure to a traumatic event. Yet, the DSM diagnostic requirements for children and adolescents for PTSD may fail to capture traumatized youth with significant distress and functional impairment. Many important studies have utilized PTSD diagnosis as a mechanism for grouping individuals for comparative studies examining brain functioning, neuroendocrinology, genetics, attachment, and cognition; however, focusing only on those with the diagnosis of PTSD can miss the spectrum of symptoms and difficulties that impact children who experience trauma and subsequent impairment...
November 9, 2016: Clinical Psychology Review
https://www.readbyqxmd.com/read/27856392/why-is-depression-more-common-among-women-than-among-men
#15
REVIEW
Christine Kuehner
Women are about twice as likely as are men to develop depression during their lifetime. This Series paper summarises evidence regarding the epidemiology on gender differences in prevalence, incidence, and course of depression, and factors possibly explaining the gender gap. Gender-related subtypes of depression are suggested to exist, of which the developmental subtype has the strongest potential to contribute to the gender gap. Limited evidence exists for risk factors to be specifically linked to depression...
November 11, 2016: Lancet Psychiatry
https://www.readbyqxmd.com/read/27855961/moderators-of-age-effects-on-attention-bias-toward-threat-and-its-association-with-anxiety
#16
Nauder Namaky, Miranda L Beltzer, Alexandra J Werntz, Ann E Lambert, Derek M Isaacowitz, Bethany A Teachman
OBJECTIVE: The current study used a research domain criteria (RDoC) approach to assess age differences in multiple indicators of attention bias and its ties to anxiety, examining stimulus domain and cognitive control as moderators of older adults' oft-cited positivity effect (bias towards positive and away from negative stimuli, when compared to younger adults). METHOD: 38 Younger adults and 38 older adults were administered a battery of cognitive control and trait and state anxiety measures, and completed a dot-probe task to assess attention bias, during which reaction time and fixation duration (using eye-tracking) were recorded for negative and neutral social (a salient threat domain for younger adults) and physical (a salient threat domain for older adults) stimuli...
November 4, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27855831/diagnostic-accuracy-of-teledentistry-in-the-detection-of-dental-caries-a-systematic-review
#17
REVIEW
Mohamed Estai, Stuart Bunt, Yogesan Kanagasingam, Estie Kruger, Marc Tennant
OBJECTIVE: This study sought to systematically review the literature for research evidence for the diagnostic accuracy of teledentistry in the detection of dental caries. METHODS: Two reviewers searched PubMed, EMBASE, and Scopus databases through January 2016 for comparative studies that examined the diagnostic accuracy of teledentistry for detecting caries compared with nontelemedicine alternatives. Retrieved studies were screened for inclusion criteria and were evaluated for methodological quality using the quality assessment of diagnostic accuracy studies (QUADAS-2) checklist...
September 2016: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/27852287/development-of-an-intervention-to-improve-appropriate-polypharmacy-in-older-people-in-primary-care-using-a-theory-based-method
#18
Cathal A Cadogan, Cristín Ryan, Jill J Francis, Gerard J Gormley, Peter Passmore, Ngaire Kerse, Carmel M Hughes
BACKGROUND: It is advocated that interventions to improve clinical practice should be developed using a systematic approach and intervention development methods should be reported. However, previous interventions aimed at ensuring that older people receive appropriate polypharmacy have lacked details on their development. This study formed part of a multiphase research project which aimed to develop an intervention to improve appropriate polypharmacy in older people in primary care. METHODS: The target behaviours for the intervention were prescribing and dispensing of appropriate polypharmacy to older patients by general practitioners (GPs) and community pharmacists...
November 16, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27847627/visual-response-and-anatomical-changes-on-sequential-spectral-domain-optical-coherence-tomography-in-birdshot-chorioretinopathy-treated-with-local-corticosteroid-therapy
#19
Marisa Gobuty, Mehreen Adhi, Sarah P Read, Jay S Duker
BACKGROUND: Birdshot chorioretinopathy is a chronic bilateral inflammatory disease of unknown etiology characterized by bilateral retinal vasculitis, mild to moderate vitritis, retinal vascular leakage, cystoid macular edema (CME), and typical "birdshot" chorioretinal lesions. Typically, patients with birdshot chorioretinopathy are treated with systemic immunosuppressive and/or corticosteroid therapy in an effort to minimize loss of vision. Spectral-domain OCT (SD-OCT) has shown regional or generalized photoreceptor loss in addition to both retinal as well as choroidal thinning in these patients...
2016: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/27846245/non-communicable-disease-clinical-practice-guidelines-in-brazil-a-systematic-assessment-of-methodological-quality-and-transparency
#20
Caroline de Godoi Rezende Costa Molino, Nicolina Silvana Romano-Lieber, Eliane Ribeiro, Daniela Oliveira de Melo
BACKGROUND: Annually, non-communicable diseases (NCDs) kill 38 million people worldwide, with low and middle-income countries accounting for three-quarters of these deaths. High-quality clinical practice guidelines (CPGs) are fundamental to improving NCD management. The present study evaluated the methodological rigor and transparency of Brazilian CPGs that recommend pharmacological treatment for the most prevalent NCDs. METHODS: We conducted a systematic search for CPGs of the following NCDs: asthma, atrial fibrillation, benign prostatic hyperplasia, chronic obstructive pulmonary disease, congestive heart failure, coronary artery disease and/or stable angina, dementia, depression, diabetes, gastroesophageal reflux disease, hypercholesterolemia, hypertension, osteoarthritis, and osteoporosis...
2016: PloS One
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