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Pimax pemax copd

Enya Daynes, Neil J Greening, Theresa C Harvey-Dunstan, Sally J Singh
BACKGROUND: COPD is characterized by expiratory flow limitation, which results in symptomatic dyspnea and reduced exercise capacity. Changes in breathing mechanics mean the respiratory muscles are unable to respond to the ventilatory demands, increasing the sensation of dyspnea. A high-frequency oscillating device has been developed to improve dyspnea in patients with COPD. We conducted a feasibility trial to gain insight into the potential for recruitment, retention, and study design for a future randomized controlled trial...
May 2018: Respiratory Care
Andiara Wolpat, Francisco V Lima, Fabiola M Silva, Micheli Tochetto, Andressa de Freitas, Tatiane Grandi, Leonardo Rodrigues, Verônica Paiva, Gerson Cipriano, Adriana M Chiappa, Julio Zago, Gaspar R Chiappa
Patients with chronic obstructive pulmonary disease (COPD) may have poor inspiratory muscle function, which reduces minute and alveolar ventilation, leading to increased hypoxemia and slow pulmonary oxygen uptake kinetics. However, little is known about the effect of inspiratory muscle weakness (IMW) on oxygen uptake kinetics in patients with COPD. Thus, we tested the hypothesis that COPD patients with IMW have slowed oxygen uptake kinetics. An observational study was conducted that included COPD patients with moderate to severe airflow limitation and a history of intolerance to exercise...
December 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Jirakrit Leelarungrayub, Decha Pinkaew, Rungthip Puntumetakul, Jakkrit Klaphajone
BACKGROUND: The aim of this study was to evaluate the efficiency of a simple prototype device for training respiratory muscles in lung function, respiratory muscle strength, walking capacity, quality of life (QOL), dyspnea, and oxidative stress in patients with COPD. METHODS: Thirty COPD patients with moderate severity of the disease were randomized into three groups: control (n=10, 6 males and 4 females), standard training (n=10, 4 males and 6 females), and prototype device (n=10, 5 males and 5 females)...
2017: International Journal of Chronic Obstructive Pulmonary Disease
Shogo Watanabe, Ippei Nojima, Yuuna Agarie, Tatsunori Watanabe, Shinichi Fukuhara, Takeshi Fujinaga, Hisao Oka
BACKGROUND: Respiratory muscle strength has been used as a tool for evaluating respiratory rehabilitation in chronic obstructive pulmonary disease. However, mouth pressure measurement evaluated by maximum expiratory mouth pressure (PEmax) or inspiratory mouth pressure (PImax) offers an indirect method for measuring respiratory muscle strength. We demonstrated the evaluation of diaphragm contractility using a mechanomyogram (MMG), which is the mechanical signal generated by the motion of the diaphragm induced by the electric stimulation of the phrenic nerve...
November 2016: Respiratory Investigation
Hideo Kaneko, Shuichi Shiranita, Jun Horie, Shinichiro Hayashi
INTRODUCTION: Advanced air-flow limitation in patients with COPD leads to a reduction in vital capacity, respiratory muscle strength, and exercise capacity. However, its impact on chest and abdominal wall mobility is unknown. This study aimed to ascertain the prevalence of patients with COPD with reduced chest and abdominal wall mobility and to investigate the effect of reduced chest and abdominal wall mobility on pulmonary function, respiratory muscle strength, and exercise capacity...
November 2016: Respiratory Care
Cássia Da Luz Goulart, Julio Cristiano Simon, Paloma De Borba Schneiders, Elisabete Antunes San Martin, Ramona Cabiddu, Audrey Borghi-Silva, Renata Trimer, Andréa Lúcia Gonçalves da Silva
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is recognized as a multisystemic inflammatory disease associated with extrapulmonary comorbidities, including respiratory muscle weakness and cardiovascular and cardiac autonomic regulation disorders. We investigated whether alterations in respiratory muscle strength (RMS) would affect cardiac autonomic modulation in COPD patients. METHODS: This study was a cross-sectional study done in ten COPD patients affected by moderate to very severe disease...
2016: International Journal of Chronic Obstructive Pulmonary Disease
Dimitra Nikoletou, Gerrard Rafferty, William D-C Man, Naveed Mustfa, Nora Donaldson, Robert L Grant, Lorna Johnson, John Moxham
BACKGROUND: Sniff nasal inspiratory pressure (SNIP) is a non-invasive measure of inspiratory muscle function often used as an outcome measure in clinical studies. An initial period of familiarisation with the test is recommended to minimise the learning effect. The repeatability of SNIP in patients with chronic obstructive pulmonary disease (COPD) is currently unknown. OBJECTIVES: The aim of this study was to assess the between-session repeatability of SNIP over a 3-week period in moderate-to-severe COPD patients and compare it with that of maximal inspiratory (PI max) and expiratory pressure (PE max)...
2014: Respiration; International Review of Thoracic Diseases
Amidio Testa, Silvia Galeri, Jorge Hugo Villafañe, Camilo Corbellini, Paolo Pillastrini, Stefano Negrini
PURPOSE: We evaluated the effectiveness of intrapulmonary percussive ventilation (IPV) compared to traditional standard chest physical therapy (CPT) in patients with chronic obstructive pulmonary disease (COPD) and productive cough. METHODS: We conducted a quasi-experimental clinical trial. Twenty patients, 40% female (mean ± SD age: 70 ± 8 years), with COPD and productive cough received a multimodal respiratory treatment including IPV and CPT or a control intervention CPT for 10 days...
2015: Disability and Rehabilitation
Leonardo F Neves, Manoela H Reis, Rodrigo D M Plentz, Darlan L Matte, Christian C Coronel, Graciele Sbruzzi
BACKGROUND: Inspiratory muscle training (IMT) produces beneficial effects in COPD subjects, but the effects of expiratory muscle training (EMT) and EMT plus IMT in ventilatory training are still unclear. The aim of this study was to systematically review the effects of EMT and EMT plus IMT compared to control groups of COPD subjects. METHODS: This study is a systematic review and meta-analysis. The search strategy included MEDLINE, Embase, LILACS, PEDro, and Cochrane CENTRAL and also manual search of references in published studies on the subject...
September 2014: Respiratory Care
Keiyu Sugawara, Hitomi Takahashi, Takeshi Kashiwagura, Kohko Yamada, Satoko Yanagida, Mitsunobu Homma, Kazuo Dairiki, Hajime Sasaki, Atsuyoshi Kawagoshi, Masahiro Satake, Takanobu Shioya
BACKGROUND: One of the major pathophysiologies in advanced chronic obstructive pulmonary disease (COPD) has been attributed to systemic inflammation. Meta-analysis of the 2005 Cochrane Database concluded the effect of nutritional supplementation alone on stable COPD was insufficient to promote body weight gain or exercise capacity. The aim of this study was to investigate the effectiveness of nutritional supplementation therapy using a nutritional supplement containing whey peptide with low-intensity exercise therapy in stable elderly patients with COPD...
November 2012: Respiratory Medicine
F Cortopassi, A A M Castro, E F Porto, M Colucci, G Fonseca, L Torre-Bouscoulet, V Iamonti, J R Jardim
BACKGROUND: Comprehensive exercise training (CET) is an efficient strategy to decrease dyspnea perception in chronic obstructive pulmonary disease (COPD) and may result in significant improvement in ventilatory muscles function. Our aim was to evaluate the effects of general exercise training on dyspnea perception and on respiratory muscles strength in COPD patients. METHODS: Consecutive COPD patients were enrolled to complete a CET programme. The patients underwent a routine that included a global warm up, upper and lower limbs endurance exercise as well as stretching and relaxation...
September 2009: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
Takanobu Shioya, Masahiro Satake, Kazuhiro Sato, Masa-aki Sano, Keiyu Sugawara, Hitomi Takahashi, Mitsunobu Honma
The present study was undertaken to evaluate the long-term effect of procaterol hydrochloride (CAS 62929-91-3, Meptin), a third generation beta2-receptor agonist on lung function, exercise capacity, health-related quality of life (HRQOL) and activities of daily living (ALDs) in patients with stable chronic obstructive pulmonary disease (COPD). Twenty patients were randomly assigned to the procaterol group or to the control group, who received oxitropium bromide (CAS 30286-75-0), an anticholinergic agent. Procaterol was inhaled three times a day at a dose of 20 pg, while oxitropium was inhaled three times a day at a dose of 200 microg...
2008: Arzneimittel-Forschung
Marta Maskey-Warzechowska, Tadeusz Przybyłowski, Katarzyna Hildebrand, Katarzyna Wrotek, Joanna Wiwała, Justyna Kościuch, Ryszarda Chazan
UNLABELLED: Many authors reported respiratory muscle function impairment in patients with chronic obstructive pulmonary disease (COPD). Impaired respiratory muscle function may contribute exercise intolerance which is frequently observed in this disease. AIM OF THE STUDY: was to determine the influence of respiratory muscle function on exercise capacity in patients with COPD. METHODS: 23 patients with stable COPD aged 62.7 +/- 9.3 years (6F, 17M; mean post-bronchodilator FEV1 = 47...
2006: Pneumonologia i Alergologia Polska
Juana M Martínez-Llorens, Mauricio Orozco-Levi, María José Masdeu, Carlos Coronell, Alba Ramírez-Sarmiento, Carles Sanjuas, Joan M Broquetas, Joaquim Gea
BACKGROUND AND OBJECTIVE: The purpose of this study was to evaluate on a prospective fashion the effects of clinical relapses of chronic obstructive pulmonary disease (COPD) on both peripheral and respiratory skeletal muscle functions. PATIENTS AND METHOD: We included 49 patients (males, 63 [11] years) who were assigned to three cohorts: a) COPD patients who were hospitalized in a conventional ward because of a relapse of their disease; b) patients hospitalized in conventional wards because of another lung disease or a pulmonary nodule; and c) COPD patients whose disease was stabilized (outpatients)...
April 17, 2004: Medicina Clínica
A Ramírez-Sarmiento, M Orozco-Levi, E Barreiro, R Méndez, A Ferrer, J Broquetas, J Gea
BACKGROUND: A reduction in expiratory muscle (ExM) endurance in patients with chronic obstructive pulmonary disease (COPD) may have clinically relevant implications. This study was carried out to evaluate ExM endurance in patients with COPD. METHODS: Twenty three patients with COPD (FEV(1) 35 (14)% predicted) and 14 matched controls were studied. ExM endurance was assessed using a method based on the use of an expiratory threshold valve which includes two steps...
February 2002: Thorax
F Marchesani, G Valerio, N Dardes, B Viglianti, C M Sanguinetti
BACKGROUND: Weight loss and skeletal muscle wasting are common in patients with chronic obstructive pulmonary disease (COPD) and can influence the course and the prognosis of COPD. Hypophosphatemia is a pathologic status often characterized by muscle weakness and is a frequent laboratory finding in these patients. OBJECTIVE: The aim of the present study was to evaluate the effect of an organic phosphate (fructose 1,6-diphosphate, FDP) administration on respiratory performance in 45 malnourished COPD patients in stable clinical conditions...
2000: Respiration; International Review of Thoracic Diseases
S Teramoto, M Suzuki, H Matsui, T Ishii, T Matsuse, Y Ouchi
We evaluated variations in spirometric indices (i.e., forced vital capacity [FVC], peak expiratory flow [PEF], and forced expiratory volume in 1 sec [FEV1]) and static respiratory muscle pressures (i.e., maximum static inspiratory pressure [PImax] and maximum static expiratory pressure [PEmax]) within a span of 12 hr in 60 healthy elderly subjects, 60 young subjects, and 30 Chronic Obstructive Pulmonary disease (COPD) patients. There were no differences among data of FVC, PEF, FEV1, PImax, and PEmax on three separate occasions within a day in the elderly or the young...
September 1999: Journal of Asthma: Official Journal of the Association for the Care of Asthma
P de Lucas Ramos, J M Rodríguez González-Moro, J García de Pedro, A Santacruz Siminiani, E Tatay Martí, J M Cubillo Marcos
The aim of this study was to evaluate the impact of inspiratory muscle training on lung function and exercise tolerance in patients with chronic obstructive pulmonary disease (COPD). Thirty-five patients with stable COPD were enrolled. We measured lung function variables and peak inspiratory and expiratory pressures (PImax and PEmax). Tests of progressive maximal exercise tolerance and stable submaximal exercise tolerance were administered. Two study groups were formed. Group A patients (n = 20) were enrolled in a respiratory muscle training program lasting four months...
February 1998: Archivos de Bronconeumología
J G Frey, T Rochat, C Pichard, N Dousse, J P Janssens, J M Tschopp
AIM OF THE STUDY: The aim of the study was to document the nutritional status and the calorie demands of patients suffering from severe chronic airflow obstruction (BPCO) who were on continuous domiciliary oxygen therapy (OCD) and to correlate this information with the clinical picture, the severity of the respiratory disease and the daily distance walked, this to be measured in a prospective manner. PATIENTS AND METHODS: Fifty clinically stable patients with chronic airflow obstruction on continuous oxygen therapy for 33 months (range 4-106) in whom the following measures were made at home: pulmonary function, maximal static inspiratory and expiratory pressure (PIMAX and PEMAX), strength of hand, grip, the mean distance walked daily (wearing a pedometer for one week), body mass index (IMC), and the body composition by electrical bio-impedence and calorie requirements...
February 1998: Revue des Maladies Respiratoires
M Montes de Oca, B R Celli, J Rassulo
The altered function of respiratory muscle function in chronic obstructive pulmonary disease (COPD) has been documented by short term studies but not by prospective follow-up. To evaluate the progression of muscle dysfunction and its relation to hyperinflation, air flow obstruction and generalized muscle weakness, we studied seven patients upon admission and 10 to 25 months later. We measured peak inspiratory (PImax) and expiratory (PEmax) pressures in the mouth, peak pleural inspiratory pressure (Pplimax) and peak transdiaphragmatic pressure (Pdimax)...
December 1997: Archivos de Bronconeumología
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