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https://www.readbyqxmd.com/read/28101161/clinical-effect-of-hydrocolloid-dressings-in-prevention-and-treatment-of-infant-diaper-rash
#1
Xiao-Ping Qiao, Yan-Zhen Ge
The aim of the study was to investigate the application of hydrocolloid dressings in the prevention and treatment of infant diaper rash. A total of 210 infants with diaper rash were included in the study and randomized into 3 groups of 70 infants. Infants in group A received hydrocolloid dressings and individualized nursing; infants in group B received mupirocin plaster and topical application of pearl powder as well as routine nursing; and infants in group C received zinc oxide plaster and routine nursing...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28096438/infection-prophylaxis-in-peritoneal-dialysis-patients-results-from-an-australia-new-zealand-survey
#2
Denise J Campbell, David W Mudge, Martin P Gallagher, Wai H Lim, Ranganathan Dwarakanathan, Walaa Saweirs, Jonathan C Craig
♦ Background: Clinical practice guidelines aim to reduce the rates of peritoneal dialysis (PD)-related infections, a common complication of PD in end-stage kidney disease patients. We describe the clinical practices used by Australian and New Zealand nephrologists to prevent PD-related infections in PD patients. ♦ Methods: A survey of PD practices in relation to the use of antibiotic and antifungal prophylaxis in PD patients was conducted of practicing nephrologists identified via the Australia and New Zealand Society of Nephrology (ANZSN) membership in 2013...
January 17, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/27999423/characterization-of-community-associated-staphylococcus-aureus-from-skin-and-soft-tissue-infections-a-multicenter-study-in-china
#3
Ying Liu, Zhe Xu, Zhou Yang, Juan Sun, Lin Ma
We evaluated the epidemiological and molecular features of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) and methicillin-sensitive S. aureus (MSSA) from children and adult patients with skin and soft-tissue infections (SSTIs) in China. Prospective community-acquired S. aureus SSTI surveillance was conducted in 23 hospitals over a 24-month period. Susceptibility to 16 antimicrobials was evaluated using the agar dilution method. StatApriori was used to determine statistically significant association trends...
December 21, 2016: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/27999015/a-single-dose-of-epidermicin-ni01-is-sufficient-to-eradicate-mrsa-from-the-nares-of-cotton-rats
#4
Samantha Halliwell, Peter Warn, Abdul Sattar, Jeremy P Derrick, Mathew Upton
OBJECTIVES: To investigate the efficacy of a potent novel antimicrobial protein of mass 6 kDa, epidermicin NI01, for eradicating the nasal burden of MRSA in a cotton rat (Sigmodon hispidus) model. METHODS: MRSA strain ATCC 43300 was used to establish a robust colonization of cotton rat nares. This model was used to evaluate the efficacy of topical 0.04% and 0.2% epidermicin NI01, administered twice daily for 3 days consecutively, and topical 0.8% epidermicin NI01 administered once, for reducing nasal MRSA burden...
December 20, 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27975885/characterisation-of-vietnamycin-a-novel-burkholderia-antibiotic-targeting-mupirocin-resistant-methicillin-resistant-staphylococcus-aureus-mrsa
#5
R A Rowe, C Jones, M J Bull, M Jenner, L Song, Y Dashti, S R Harris, J Parkhill, T R Connor, G L Challis, E Mahenthiralingam
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27907108/mupirocin-in-the-treatment-of-staphylococcal-infections-in-chronic-rhinosinusitis-a-meta-analysis
#6
Jong Seung Kim, Sam Hyun Kwon
BACKGROUND: Saline irrigation of the nasal cavity is a classic and effective treatment for acute or chronic rhinosinusitis. Topical antibiotics such as mupirocin have been widely used for recalcitrant chronic rhinosinusitis. Therefore, the purpose of this study was to evaluate the effect of saline irrigation using mupirocin. METHODS: A systematic literature review and meta-analysis of mupirocin saline irrigation were performed using EMBASE, MEDLINE, and Cochrane library through December 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27903852/topical-honey-in-the-management-of-pediatric-peritoneal-dialysis-exit-sites
#7
Thomas A Forbes, Loren Shaw, Catherine Quinlan
International guidelines in peritoneal dialysis (PD) advocate for regular application of topical mupirocin in chronic PD exit-site care. A strong evidence base links this treatment to reduced rates of exit-site infections and peritonitis. However, emerging reports of increasing mupirocin resistance and gram-negative infections are threatening the long-term viability of topical antibiotic ointments as a prophylactic treatment. Medical grade honey has multiple proven antibacterial and wound healing properties...
November 2016: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/27875687/complete-substitution-of-the-brazilian-endemic-clone-by-other-methicillin-resistant-staphylococcus-aureus-lineages-in-two-public-hospitals-in-rio-de-janeiro-brazil
#8
Raiane Cardoso Chamon, Sthefanie da Silva Ribeiro, Thaina Miranda da Costa, Simone Aranha Nouér, Katia Regina Netto Dos Santos
Staphylococcus aureus is an important cause of bloodstream infections. Therefore, the main purpose of this work was to characterize a collection of 139 S. aureus isolates from bloodstream infections in two public hospitals in relation to their antimicrobial susceptibility profile, staphylococcal cassette chromosome mec types, and clonal relationship. Methicillin resistance and resistance to other 12 agents were accessed by the disk diffusion test. Minimum inhibitory concentration to mupirocin was also determined...
November 19, 2016: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27869429/-topical-corticosteroids-as-a-therapeutic-alternative-in-linear-immunoglobulin-a-bullous-dermatosis-in-childhood-case-report
#9
Francisco José Gil Sáenz, Gabriel Durán Urdániz, Marta Fernández Galar, Juan Gimeno Ballester, Ana Herrero Varasa, Rosa Garcés Bordege
Linear immunoglobulin A dermatosis of childhood is a rare autoimmune disorder. Its etiology remains unknown, although it has been linked to drugs, infections, immunological diseases and lymphoproliferative processes. We report the case of a 6 year old girl who consulted for perioral bullous lesions without other symptoms. Neither treatment with mupirocin nor methylprednisolone therapy achieved remission of cutaneous lesions. Skin biopsy showed a linear immunoglobulin A dermatosis. It was not possible to start treatment with dapsone because of a partial glucose-6-phosphate dehydrogenase deficiency, so topical treatment was maintained with good evolution of lesions...
December 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27859922/cadexomer-iodine-provides-superior-efficacy-against-bacterial-wound-biofilms-in-vitro-and-in-vivo
#10
Daniel J Fitzgerald, Paul J Renick, Emma C Forrest, Shannon P Tetens, David N Earnest, Jillian McMillan, Brett M Kiedaisch, Lei Shi, Eric D Roche
Examination of clinical samples indicates bacterial biofilms are present in the majority of chronic wounds, and substantial evidence suggests biofilms contribute significantly to delayed healing. Bacteria in biofilms are highly tolerant of antimicrobials, and little data exist to guide the choice of anti-biofilm wound therapy. Cadexomer iodine (CI) was recently reported to have superior efficacy compared to diverse wound dressings against Pseudomonas aeruginosa biofilms in an ex vivo model. In the current study, the strong performance of CI vs...
November 17, 2016: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/27853689/the-effect-of-oliveria-decumbens-and-pelargonium-graveolens-on-healing-of-infected-skin-wounds-in-mice
#11
Mohaddese Mahboubi, Mohammad Mehdi Feizabadi, Tahereh Khamechian, Nastaran Kazempour, Mohsen Razavi Zadeh, Farhang Sasani, Mohsen Bekhradi
BACKGROUND: Staphylococcus aureus is one of the most causative organisms in the skin wound infections. Development of resistant S. aureus to current treatments in individuals with low immunity is a global concern. The aim of this study was to evaluate the efficacy of herbal formulation against skin wound infection. METHODS: The efficacy of herbal formulation containing Oliveria decumbens and Pelargonium graveolens essential oils was evaluated in comparison to mupirocin against Methicillin Resistant S...
September 2016: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/27852955/microbiological-efficacy-of-early-mrsa-treatment-in-cystic-fibrosis-in-a-randomised-controlled-trial
#12
Marianne Sponer Muhlebach, Valeria Beckett, Elena Popowitch, Melissa B Miller, Arthur Baines, Nicole Mayer-Hamblett, Edith T Zemanick, Wynton C Hoover, Jill M VanDalfsen, Preston Campbell, Christopher H Goss
OBJECTIVE: To evaluate microbiological effectiveness, that is, culture negativity of a non-blinded eradication protocol (Rx) compared with observation (Obs) in clinically stable cystic fibrosis participants with newly positive methicillin resistant Staphylococcus aureus (MRSA) cultures. DESIGN: This non-blinded trial randomised participants ages 4-45 years with first or early (≤2 positive cultures within 3 years) MRSA-positive culture without MRSA-active antibiotics within 4 weeks 1:1 to Rx or Obs...
November 15, 2016: Thorax
https://www.readbyqxmd.com/read/27848275/electrospun-mupirocin-loaded-polyurethane-fiber-mats-for-anti-infection-burn-wound-dressing-application
#13
Xinxin Chen, Rui Zhao, Xiang Wang, Xiang Li, Fei Peng, Zhenghua Jin, Xinxin Gao, Jiaao Yu, Ce Wang
Wound care treatment is a serious issue faced by the medical staffs due to its variety and complexity. Wound dressings are typically used to manage the various types of wounds. In this study, polyurethane (PU) fibers containing mupirocin (Mu), a commonly used antibiotic in wound care, were fabricated via electrospinning technique. The aim of this study was to develop biomedical electrospun fiber scaffolds for preventing wound infections with good compatibility and to demonstrate their applications as anti-infective burn wound dressings...
February 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/27828836/the-impact-of-a-universal-decolonization-protocol-on-hospital-acquired-methicillin-resistant-staphylococcus-aureus-in-a-burn-population
#14
Arthur T Johnson, Rachel M Nygaard, Ellie M Cohen, Ryan M Fey, Anne Lambert Wagner
Hospital-acquired (HA) methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of HA infections and a significant concern for burn centers. The use of 2% chlorhexidine-impregnated wipes and nasal mupirocin significantly decreases the rate of HA-MRSA in adult intensive care units. The aim of this study was to examine the impact of universal decolonization on the rate of MRSA conversion in an American Burn Association verified adult and pediatric burn center. Universal decolonization protocol consisting of daily chlorhexidine baths and a 5-day course of nasal mupirocin was implemented in the burn unit...
November 2016: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/27828633/staphylococcus-aureus-resistance-to-topical-antimicrobials-in-atopic-dermatitis
#15
Giancarlo Rezende Bessa, Vanessa Petry Quinto, Daiane Corrêa Machado, Caroline Lipnharski, Magda Blessmann Weber, Renan Rangel Bonamigo, Pedro Alves D'Azevedo
Background: Topical antimicrobial drugs are indicated for limited superficial pyodermitis treatment, although they are largely used as self-prescribed medication for a variety of inflammatory dermatoses, including atopic dermatitis. Monitoring bacterial susceptibility to these drugs is difficult, given the paucity of laboratory standardization. Objective: To evaluate the prevalence of Staphylococcus aureus topical antimicrobial drug resistance in atopic dermatitis patients...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/27823845/decreased-hospital-costs-and-surgical-site-infection-incidence-with-a-universal-decolonization-protocol-in-primary-total-joint-arthroplasty
#16
Jeffrey B Stambough, Denis Nam, David K Warren, James A Keeney, John C Clohisy, Robert L Barrack, Ryan M Nunley
BACKGROUND: Staphylococcus aureus colonization has been identified as a key modifiable risk factor in the reduction of surgical site infections (SSI) related to elective total joint arthroplasty (TJA). We investigated the incidence of SSIs and cost-effectiveness of a universal decolonization protocol without screening consisting of nasal mupirocin and chlorhexidine before elective TJA compared to a program in which all subjects were screened for S aureus and selectively treated if positive...
October 8, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27819748/topical-antibiotics-for-preventing-surgical-site-infection-in-wounds-healing-by-primary-intention
#17
REVIEW
Clare F Heal, Jennifer L Banks, Phoebe D Lepper, Evangelos Kontopantelis, Mieke L van Driel
BACKGROUND: Surgical site infections (SSI) can delay wound healing, impair cosmetic outcome and increase healthcare costs. Topical antibiotics are sometimes used to reduce microbial contaminant exposure following surgical procedures, with the aim of reducing SSIs. OBJECTIVES: The primary objective of this review was to determine whether the application of topical antibiotics to surgical wounds that are healing by primary intention reduces the incidence of SSI and whether it increases the incidence of adverse outcomes (allergic contact dermatitis, infections with patterns of antibiotic resistance and anaphylaxis)...
7, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27804112/carriage-rate-and-antibiotic-susceptibility-of-coagulase-positive-staphylococci-isolated-from-healthy-dogs-in-victoria-australia
#18
D C Bean, S M Wigmore
BACKGROUND: Studies in Australia and elsewhere have shown high levels of antibiotic resistance in coagulase-positive staphylococci in dogs visiting veterinary clinics with pyoderma and related conditions. Although important, such studies tend to overestimate the burden of resistance. The aim of the current study was to investigate the prevalence of coagulase-positive staphylococci in healthy dogs in Central Victoria to assess the level of antibiotic resistance among these isolates. METHODS: We recruited 117 healthy dogs into the study...
December 2016: Australian Veterinary Journal
https://www.readbyqxmd.com/read/27795221/-acute-generalized-exanthematous-pustulosis-induced-by-piroxicam
#19
Ingrid Bissinger, Gustavo Matute-Turizo, María Natalia Mejía-Barreneche
BACKGROUND: Between 62 and 90% of cases of acute generalized exanthematous pustulosis are caused by drugs. Its onset is rapid with generalized pustules, fever, and blood neutrophil count over 7000; pustules resolve spontaneously in less than 15 days. A case associated with piroxicam described. CASE REPORT: A 36-year-old with initial erythema of the thorax and abdomen, accompanied by burning, without fever, which later spread to his forearms, upper arms, and thighs, with face edema...
October 2016: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/27790966/epidemiology-and-microbiological-characterization-of-clinical-isolates-of-staphylococcus-aureus-in-a-single-healthcare-region-of-the-uk-2015
#20
C Horner, L Utsi, L Coole, M Denton
We investigated the epidemiology and characterization of isolates of Staphylococcus aureus within the Yorkshire and Humber (YH) region in the UK. In July 2015, each laboratory within YH (n = 14) was assigned two consecutive days during which all clinical isolates of S. aureus were collected. Isolates were tested for antibiotic susceptibilities and the presence of genes encoding methicillin resistance (mecA and mecC), Panton-Valentine leukocidin (PVL) (lukS-PV), and efflux-mediated chlorhexidine resistance (qacA); isolates were also characterized by spa-types...
January 2017: Epidemiology and Infection
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