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Green tea extract

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https://www.readbyqxmd.com/read/28813122/morphological-alterations-in-the-jejunal-mucosa-of-aged-rats-and-the-possible-protective-role-of-green-tea
#1
Zeinab Abel-Rehim Hassan, Agata Zauszkiewicz-Pawlak, Shaimaa A Abdelrahman, Sami Algaidi, Maha Desouky, Sally M Shalaby
INTRODUCTION: Gastrointestinal disorders become more prevalent with ageing. This study is aimed to describe morphological changes that occur in the jejunal mucosa of male albino rats as a result of ageing and the protective effect of green tea supplements. MATERIAL AND METHODS: The experiment was performed on sixty rats: thirty young-adult (6-month old, body mass 200-220 g) and thirty old (24-month-old, body mass 220-260 g) animals. Each group was further divided into two subgroups (n = 15 each): control rats and green tea-treated rats that received 1...
August 16, 2017: Folia Histochemica et Cytobiologica
https://www.readbyqxmd.com/read/28804438/green-tea-extract-induces-genes-related-to-browning-of-white-adipose-tissue-and-limits-weight-gain-in-high-energy-diet-fed-rat
#2
Li-Han Chen, Yi-Wen Chien, Chung-Tiang Liang, Ching-Hung Chan, Meng-Han Fan, Hui-Yu Huang
Background: A wealth of research has reported on the anti-obesity effects of green tea extract (GTE). Although browning of white adipose tissue (WAT) has been reported to attenuate obesity, no study has disclosed the effects of GTE on browning in Sprague Dawley rats. Objectives: The aims of the study were to investigate the effects of GTE on anti-obesity and browning, and their underlying mechanisms. Methods: Four groups of rats (n=10/group) were used including a normal diet with vehicle treatment, and a high-energy diet (HED) with vehicle or GTE by oral gavage at 77...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28799714/potential-biological-effects-of-epigallocatechin-3-gallate-on-the-treatment-of-nonalcoholic-fatty-liver-disease
#3
REVIEW
Cheng Chen, Qian Liu, Lin Liu, Yi-Yang Hu, Qin Feng
Nonalcoholic fatty liver disease (NAFLD) is a major health issue throughout the world. However, no validated treatments for NAFLD are currently available. In-depth studies have demonstrated the efficacy of (-)-epigallocatechin-3-gallate (EGCG), a main bioactive chemical extracted from green tea, in treating NAFLD. EGCG exhibits multi-pronged preventive and therapeutic activities, including promoting lipid and glucose metabolism, anti-lipid peroxidation and anti-inflammation activities, anti-fibrosis, and anti-NAFLD related tumor, thus contributing to the mitigation of NAFLD occurrence and progression...
August 11, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28798484/epigallocatechin-3-gallate-inhibits-h2o2-induced-apoptosis-in-mouse-vascular-smooth-muscle-cells-via-67kd-laminin-receptor
#4
Xue Yan, Yanfei Li, Han Yu, Wei Wang, Chunyan Wu, Yang Yang, Yongjia Hu, Xiujuan Shi, Jue Li
Epigallocatechin-3-gallate (EGCG) is one of the major polyphenolic compounds present in green tea extracts and has been used as a potential drug for the treatment of numerous diseases. The present study aimed to elucidate the role and mechanism of EGCG in protecting against H2O2-induced apoptosis in mouse vascular smooth muscle cells (VSMCs). VSMCs were pretreated with various concentrations of EGCG for 2 hours prior to treatment with H2O2. Treatment with H2O2 significantly decreased the cell viability and induced apoptosis of VSMCs, which were attenuated by pretreatment with EGCG...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28792903/hydrocalumite-thin-films-for-polyphenol-biosensor-elaboration
#5
A Soussou, I Gammoudi, A Kalboussi, C Grauby-Heywang, T Cohen-Bouhacina, Z M Baccar
Hybrid thin films based on Hydrocalumite (Ca2AlCl layered double hydroxide LDH) and tyrosinase enzyme have been used for the elaboration of a high sensitive amperometric biosensor detecting polyphenols extracted from green tea. Structural properties of LDH nanomaterials were characterized by X-ray powder diffraction and Infra-Red spectroscopy, confirming its crystalline phase and chemical composition. Ca2AlCl-LDHs-thin films were deposited by spin-coating, and studied by Atomic Force Microscopy (AFM) to obtain information about the surface morphology of this host matrix before and after enzyme's immobilization...
August 7, 2017: IEEE Transactions on Nanobioscience
https://www.readbyqxmd.com/read/28792381/effects-of-tea-extracts-on-the-colonization-behaviour-of-candida-species-attachment-inhibition-and-biofilm-enhancement
#6
Yi Wang, H M H N Bandara, Deirdre Mikkelsen, Lakshman P Samaranayake
PURPOSE: We assessed the effects of four different types of tea extracts (green, oolong, black and pu-erh tea) on cellular surface properties (hydrophobicity and auto-aggregation) and the colonization attributes (attachment and biofilm formation) of four strains of Candida albicans and three strains of Candida krusei. METHODOLOGY: The cellular surface properties were determined using spectrophotometry. The colonization activities were quantified using colorimetric viability assays and visualized using scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM)...
August 10, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28781899/the-effect-of-tributyltin-on-thyroid-follicular-cells-of-adult-male-albino-rats-and-the-possible-protective-role-of-green-tea-a-toxicological-histological-and-biochemical-study
#7
Fatma M M Badr El Dine, Iman M Nabil, Fatma I Dwedar
INTRODUCTION: Tributyltin is one of the important and wide-spread persistent organic contaminants that accumulate in the food chain. It is suspected to cause endocrine-disrupting effects in mammals, due in part to its possible transfer through marine food chains and to the consumption of contaminated seafood. AIM OF THE WORK: Was to study the possible toxic effect of Tributyltin on thyroid follicular cells of adult male albino rats and to evaluate the possible protective role of green tea...
2017: Egyptian journal of forensic sciences
https://www.readbyqxmd.com/read/28777065/possible-role-of-antioxidative-capacity-of-epigallocatechin-3-gallate-treatment-in-morphological-and-neurobehavioral-recovery-after-sciatic-nerve-crush-injury
#8
Waleed M Renno, Ludmil Benov, Khalid M Khan
OBJECTIVE This study examined the capacity of the major polyphenolic green tea extract (-)-epigallocatechin-3-gallate (EGCG) to suppress oxidative stress and stimulate the recovery and prompt the regeneration of sciatic nerve after crush injury. METHODS Adult male Wistar rats were randomly assigned to one of 4 groups: 1) Naïve, 2) Sham (sham injury, surgical control group), 3) Crush (sciatic nerve crush injury treated with saline), and 4) Crush+EGCG (sciatic nerve crush injury treated with intraperitoneally administered EGCG, 50 mg/kg)...
August 4, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28765194/effect-of-green-tea-supplements-on-liver-enzyme-elevation-results-from-a-randomized-intervention-study-in-the-united-states
#9
Zheming Yu, Hamed Samavat, Allison Dostal, Renwei Wang, Carolyn J Torkelson, Chung S Yang, Lesley M Bulter, Thomas W Kensler, Anna H Wu, Mindy S Kurzer, Jian-Min Yuan
Liver injury effects of green tea-based products have been reported in sporadic case reports. However, no study has examined systematically such adverse effects in an unbiased manner. We examined the potential effects of a high, sustained oral dose of green tea extract (GTE) on liver injury measures in a randomized, placebo-controlled, double-blinded phase II clinical trial, which enrolled 1,075 women with the original aim to assess the effect of daily GTE consumption for 12 months on biomarkers of breast cancer risk...
August 1, 2017: Cancer Prevention Research
https://www.readbyqxmd.com/read/28762712/common-herbal-dietary-supplement-drug-interactions
#10
REVIEW
Gary N Asher, Amanda H Corbett, Roy L Hawke
Nearly 25% of U.S. adults report concurrently taking a prescription medication with a dietary supplement. Some supplements, such as St. John's wort and goldenseal, are known to cause clinically important drug interactions and should be avoided by most patients receiving any pharmacologic therapy. However, many other supplements are predicted to cause interactions based only on in vitro studies that have not been confirmed or have been refuted in human clinical trials. Some supplements may cause interactions with a few medications but are likely to be safe with other medications (e...
July 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/28760074/redox-status-on-different-regions-of-the-central-nervous-system-of-obese-and-lean-rats-treated-with-green-tea-extract
#11
Rita Cassia Macedo, Eduardo Fernandes Bondan, Rosemari Otton
OBJECTIVES: The purpose of this study was to evaluate some indicators of redox status, and inflammation on different regions of the central nervous system (CNS) of obese rats treated with green tea (GT). We hypothesized that obesity could affect the redox balance in different brain regions due to the diverse nature of the cells as well as the selective neuronal vulnerability to oxidative stress, and GT could triggers benefits effects restoring the redox status. METHODS: Male Wistar rats were treated with GT by gavage (12 weeks/5 days/week; 500 mg/kg of body weight) and obesity was induced by cafeteria diet (8 weeks)...
July 31, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28753942/quercetin-and-green-tea-extract-supplementation-downregulates-genes-related-to-tissue-inflammatory-responses-to-a-12-week-high-fat-diet-in-mice
#12
Lynn Cialdella-Kam, Sujoy Ghosh, Mary Pat Meaney, Amy M Knab, R Andrew Shanely, David C Nieman
Quercetin (Q) and green tea extract (E) are reported to counter insulin resistance and inflammation and favorably alter fat metabolism. We investigated whether a mixture of E + Q (EQ) could synergistically influence metabolic and inflammation endpoints in a high-fat diet (HFD) fed to mice. Male C57BL/6 mice (n = 40) were put on HFD (fat = 60%kcal) for 12 weeks and randomly assigned to Q (25 mg/kg of body weight (BW)/day), E (3 mg of epigallocatechin gallate/kg BW/day), EQ, or control groups for four weeks. At 16 weeks, insulin sensitivity was measured via the glucose tolerance test (GTT), followed by area-under-the-curve (AUC) estimations...
July 19, 2017: Nutrients
https://www.readbyqxmd.com/read/28750751/the-anti-aging-and-anti-oxidation-effects-of-tea-water-extract-in-caenorhabditis-elegans
#13
Tianyi Fei, Jian Fei, Fang Huang, Tianpei Xie, Jifeng Xu, Yi Zhou, Ping Yang
Tea includes puer tea, black tea, green tea and many others. By using model organism Caenorhabditis elegans, the anti-aging and anti-oxidation effects of tea water extract were systemically examined in this study. We found that water extract of puer tea, black tea and green tea all increased the lifespan of worms, postponed Aβ-induced progressive paralysis in Alzheimer's disease transgenic worms, and improved the tolerance of worms to the oxidative stress induced by heavy metal Cr(6+). Moreover, the anti-oxidation effects of tea water extract at low concentration were different among 4 kinds of brands of green tea...
July 25, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28725904/cellular-antioxidant-methylglyoxal-trapping-and-anti-inflammatory-activities-of-cocoa-tea-camellia-ptilophylla-chang
#14
Xiong Gao, Xiaorong Lin, Xiaofei Li, Yuanyuan Zhang, Zhongzheng Chen, Bin Li
Cocoa tea (Camellia ptilophylla Chang) is a naturally low caffeine-containing but gallocatechin gallate (GCG)-rich tea cultivar, though its biological activities have not been extensively explored. Herein, we evaluated the in vitro cellular antioxidant, methylglyoxal trapping, and anti-inflammatory activities of water extract of green tea from cocoa tea (CWE) and Yunnan Daye tea (Camellia sinensis) (YWE), and their predominant bioactive components GCG and epigallocatechin gallate (EGCG) for comparative purposes...
August 1, 2017: Food & Function
https://www.readbyqxmd.com/read/28722393/multiligand-metal-phenolic-assembly-from-green-tea-infusions
#15
Md Arifur Rahim, Mattias Björnmalm, Nadja Bertleff-Zieschang, Yi Ju, Srinivas Mettu, Michael G Leeming, Frank Caruso
The synthesis of hybrid functional materials using the coordination-driven assembly of metal-phenolic networks (MPNs) is of interest in diverse areas of materials science. To date, MPN assembly has been explored as monoligand systems (i.e., containing a single type of phenolic ligand) where the phenolic components are primarily obtained from natural sources via extraction, isolation, and purification processes. Herein, we demonstrate the fabrication of MPNs from a readily available, crude phenolic source-green tea (GT) infusions...
July 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28720978/extraction-and-preparation-of-high-aroma-and-low-caffeine-instant-green-teas-by-the-novel-column-chromatographic-extraction-method-with-gradient-elution
#16
Qing-Rong Li, Min Wu, Rui-Jie Huang, Ya-Fei Chen, Chan-Jian Chen, Hui Li, He Ni, Hai-Hang Li
The lack of aroma and natural taste is a critical problem in production and consumption of instant green teas. A method to prepare instant green teas high in-natural-aroma and low-caffeine by the novel column chromatographic extraction with gradient elution is reported. This method simultaneously extracted aroma (or volatile) and non-aroma compounds from green tea. Green tea was loaded into columns with 2.0-fold of petroleum ether (PE): ethanol (8:2). After standing for 3 h until the aroma compounds dissolved, the column was sequentially eluted with 3...
June 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28707966/targeted-molecular-ablation-of-cancer-stem-cells-for-curing-gastrointestinal-cancers
#17
Yong Seok Kim, Ho Jae Lee, Jong-Min Park, Young-Min Han, Napapan Kangwan, Ji Young Oh, Dong Yoon Lee, Ki Baik Hahm
Abundance of the ATPase-binding cassette (ABC) transporters and deranged self-renewal pathways characterize the presence of cancer stem cells (CSCs) in gastrointestinal cancers (GI cancers), which play crucial roles in tumorigenesis, chemotherapy resistance, tumor recurrence, and cancer metastasis. Therefore, in order to ensure high cure rates, chemoquiescence, CSCs should be ablated. Recent advances in either understanding CSCs or biomarker identification enable scientists to develop techniques for ablating CSCs and clinicians to provide cancer cure, especially in GI cancers characterized by inflammation-driven carcinogenesis...
July 14, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28680384/randomized-controlled-trial-of-the-effects-of-consumption-of-yabukita-or-benifuuki-encapsulated-tea-powder-on-low-density-lipoprotein-cholesterol-level-and-body-weight
#18
Yuko Igarashi, Taku Obara, Mami Ishikuro, Hiroko Matsubara, Michiko Shigihara, Hirohito Metoki, Masahiro Kikuya, Yoichi Sameshima, Hirofumi Tachibana, Mari Maeda-Yamamoto, Shinichi Kuriyama
Background: Previous studies have reported controversial results for the association between green tea consumption and low-density lipoprotein (LDL)-cholesterol and body weight. Objective: The objective of this trial was to determine the effects of two kinds of green tea on LDL-cholesterol and body weight. Methods: We randomly assigned 151 participants (98 men, 53 women) aged 30-70 years into three groups: Yabukita green tea group, Benifuuki green tea group, or placebo group. Participants consumed 1.8 g/day of green tea extract powder or placebo for 12 weeks...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28678746/long-term-supplementation-of-decaffeinated-green-tea-extract-does-not-modify-body-weight-or-abdominal-obesity-in-a-randomized-trial-of-men-at-high-risk-for-prostate-cancer
#19
Nagi B Kumar, Roshni Patel, Julio Pow-Sang, Philippe E Spiess, Raoul Salup, Christopher R Williams, Michael J Schell
BACKGROUND: Evidence continues to demonstrate the role of obesity in prostate carcinogenesis and prognosis, underscoring the need to identify and continue to evaluate the effective interventions to reduce obesity in populations at high risk. The aim of the study was to determine the effect of daily consumption of decaffeinated green tea catechins (GTC) formulation (Polyphenon E® (PolyE)) for 1 year on biomarkers of obesity in men who are at high risk for prostate cancer. MATERIALS AND METHODS: A randomized, double-blinded trial was conducted targeting 97 men diagnosed with HGPIN or ASAP...
June 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28672835/magnetic-solid-phase-extraction-with-fe%C3%A2-o%C3%A2-molecularly-imprinted-polymers-modified-by-deep-eutectic-solvents-and-ionic-liquids-for-the-rapid-purification-of-alkaloid-isomers-theobromine-and-theophylline-from-green-tea
#20
Guizhen Li, Xiaoqin Wang, Kyung Ho Row
Different kinds of deep eutectic solvents (DES) based on choline chloride (ChCl) and ionic liquids (ILs) based on 1-methylimidazole were used to modify Fe3O4/molecularly imprinted polymers (Fe3O4/MIPs), and the resulting materials were applied for the rapid purification of alkaloid isomers (theobromine and theophylline) from green tea with magnetic solid-phase extraction (M-SPE). The M-SPE procedure was optimized using the response surface methodology (RSM) to analyze the maximum conditions. The materials were characterized by Fourier transform infrared spectroscopy (FI-IR) and field emission scanning electron microscopy (FE-SEM)...
June 25, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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