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Green tea extract

Brian J Martin, Chris McGlory, Martin J MacInnis, Mary K Allison, Stuart M Phillips, Martin J Gibala
We reported that supplementation with green tea extract (GTE) lowered the glycemic response to an oral glucose load following exercise but via an unknown mechanism. Here we examined the effect of supplementation with GTE on plasma glucose kinetics upon ingestion of a glucose beverage during exercise recovery. Eleven healthy, sedentary men (21±2 y; BMI=23±4 kg•m(-2), VO2peak=38±7 ml•kg(-1)•min(-1); mean±SD) ingested GTE (350 mg) or placebo (PLA) thrice daily for 7-d in a double-blind, crossover design...
October 7, 2016: Journal of Applied Physiology
Naga Pavan Kumar Chevala, Naga Thirumalesh Chevala, Kirubakaran Dhanakodi, Rama Rao Nadendla, Chandrashekara Krishnappa Nagarathna
BACKGROUND: Tea is an economic important crop with high medicinal value due to rich polyphenols content. In the present research we studied the accumulation of polyphenols of in vitro regenerated callus from anthers. OBJECTIVE: Callus induction of tea anthers and in vitro accumulation of phenolic compounds from the anther-derived callus. MATERIALS AND METHODS: Standardization of callus induction for tea anthers. In vitro generated callus was screened for in vivo accumulation of catechins and its isomers were screened by FC reagent staining technique...
July 2016: Pharmacognosy Magazine
Ji-Young Choi, Ye Jin Kim, Ri Ryu, Su-Jung Cho, Eun-Young Kwon, Myung-Sook Choi
Green tea (GT) has various health effects, including anti-obesity properties. However, the multiple molecular mechanisms of the effects have not been fully determined. The aim of this study was to elucidate the anti-obesity effects of GT via the analysis of its metabolic and transcriptional responses based on RNA-seq profiles. C57BL/6J mice were fed a normal, high-fat (60% energy as fat), or high-fat + 0.25% (w/w) GT diet for 12 weeks. The GT extract ameliorated obesity, hepatic steatosis, dyslipidemia, and insulin resistance in diet-induced obesity (DIO) mice...
October 14, 2016: Nutrients
Amani F Abaza, Osama N Mohamed, Fathy K El-Fiky, Khaled A Ahmed
OBJECTIVES: This study aimed to determine the occurrence of methicillin-resistant Staphylococcus aureus (MRSA) nasal carriage among patients, healthcare workers (HCWs), and community individuals, as well as to test the effect of tea extracts on detected S. aureus isolates. MATERIALS AND METHODS: This cross-sectional study that was followed by an experimental study included a total of 1021 nasal swab samples that were collected from 470 community cases, 191 HCWs, and 360 patients...
September 2016: Journal of the Egyptian Public Health Association
Amir Hadi, Makan Pourmasoumi, Marzieh Kafeshani, Jahangir Karimian, Mohammad Reza Maracy, Mohammad Hasan Entezari
OBJECTIVE: Additional oxygen consumption during intense exercises may lead to oxidative stress and contribute to muscular fatigue. Green tea and sour tea (Hibiscus sabdariffa L.), which contain various flavonoids and polyphenols, have many healthful properties such as anticarcinogenic, anti-inflammatory, and heart protecting effects. The aim of the present study was to assess the effects of green tea and sour tea supplementation on oxidative stress and muscle damage in soccer athletes...
October 13, 2016: Journal of Dietary Supplements
Maheswata Sahoo, Lingaraja Jena, Surya Narayan Rath, Satish Kumar
The influenza A (H1N1) virus, also known as swine flu is a leading cause of morbidity and mortality since 2009. There is a need to explore novel anti-viral drugs for overcoming the epidemics. Traditionally, different plant extracts of garlic, ginger, kalmegh, ajwain, green tea, turmeric, menthe, tulsi, etc. have been used as hopeful source of prevention and treatment of human influenza. The H1N1 virus contains an important glycoprotein, known as neuraminidase (NA) that is mainly responsible for initiation of viral infection and is essential for the life cycle of H1N1...
September 2016: Genomics & Informatics
Mai Yamashita, Motofumi Kumazoe, Yuki Nakamura, Yeong Seon Won, Jaehoon Bae, Shuya Yamashita, Hirofumi Tachibana
Western diets induce obesity associated with an increased risk of hypercholesterolaemia. Indeed, obesity-induced hypercholesterolaemia is correlated with increased coronary cardiovascular disease (CVD) risk. Male C57BL/6J mice were fed a normal diet, high-fat and high-sucrose diet (HF/HS), HF/HS with green tea extract powder diet (HF/HS+GT), HF/HS with eriodictyol diet (HF/HS+Eri), or HF/HS with green tea extract powder and eriodictyol diet (HF/HS+GT+Eri) for 8 wk. Body weight was lower in the HF/HS+GT+Eri group than in the HF/HS group (-8...
2016: Journal of Nutritional Science and Vitaminology
Tandeka Magcwebeba, Pieter Swart, Sonja Swanevelder, Elizabeth Joubert, Wentzel Gelderblom
Ultraviolet B (UVB) radiation is one of the major predisposing risk factors of skin cancer. The anticancer and photoprotective effects of unoxidized rooibos (Aspalathus linearis) and honeybush (Cyclopia) herbal teas, containing high levels of dihydrochalones and xanthones, respectively, have been demonstrated in skin cancer models in vivo. In the current study, the anti-inflammatory effects of methanol and aqueous extracts of these herbal teas were investigated in a UVB/HaCaT keratinocyte model with intracellular interleukin-1α (icIL-1α) accumulation as a biomarker...
October 2, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Xiu Hong Yang, Yu Pan, Xiao Li Zhan, Bao Long Zhang, Li Li Guo, Hui Min Jin
Epigallocatechin-3-gallate (EGCG), extracted from green tea, has been shown to have antioxidative activity. In the present study, we evaluated the effect of EGCG on the kidney function in db/db mice and also tried to investigate the underlying mechanism of the renoprotective effects of EGCG in both animals and cells. EGCG treatment could decrease the level of urinary protein, 8-iso-PGF2a, and Ang II. Moreover, EGCG could also change the level of several parameters associated with oxidative stress. In addition, the protein expression levels of AT-1R, p22-phox, p47-phox, p-ERK1/2, p-p38 MAPK, TGF-β1, and α-SMA in diabetic db/db mice were upregulated, and all of these symptoms were downregulated with the treatment of EGCG at 50 and 100 mg/kg/d...
2016: Oxidative Medicine and Cellular Longevity
M Münzner, N Tappenbeck, F Gembardt, R Rülke, J Furkert, M F Melzig, W-E Siems, G A Brockmann, T Walther
BACKGROUND/OBJECTIVE: Consumption of Green Tea has become increasingly popular, particularly because of claimed reduction in body weight. We recently reported that animals with pharmacological inhibition (by candoxatril) or genetic absence of the endopeptidase neprilysin (NEP) develop an obese phenotype. We now investigated the effect of Green Tea extract (in drinking water) on body weight and body composition and the mediating role of NEP. SUBJECTS/METHODS: To elucidate the role of NEP in mediating the beneficial effects of Green Tea extract, 'Berlin fat mice' or NEP-deficient mice and their age-and gender-matched wild-type controls received the extract in two different doses (300 or 600 mg/kg body weight/day) in the drinking water...
October 4, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Amel Ben Lagha, Daniel Grenier
Fusobacterium nucleatum has been associated with both periodontal disease and inflammatory bowel disease. This Gram-negative bacterium possesses a high inflammatory potential that may contribute to the disease process. We hypothesized that green and black tea polyphenols attenuate the inflammatory response of monocytes/macrophages mediated by F. nucleatum. We first showed that the tea extracts, EGCG and theaflavins reduce the NF-κB activation induced by F. nucleatum in monocytes. Since NF-κB is a key regulator of genes coding for inflammatory mediators, we tested the effects of tea polyphenols on secretion of IL-1β, IL-6, TNF-α, and CXCL8 by macrophages...
October 3, 2016: Scientific Reports
Brian J Martin, Martin J MacInnis, Jenna B Gillen, Lauren E Skelly, Martin J Gibala
Green tea extract (GTE) ingestion improves glucose homeostasis in healthy and diabetic humans, but the interactive effect of GTE and exercise is unknown. The present study examined the effect of short-term GTE supplementation on the glycemic response to an oral glucose load at rest and following an acute bout of exercise, as well as substrate oxidation during exercise. Eleven sedentary, overweight men with fasting plasma glucose (FPG) ≥5.6 mmol·L(-1) (age, 34 ± 13 years; body mass index = 32 ± 5 kg·m(-2); FPG = 6...
June 15, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Xiangyu Wang, Anqi Wang, Jun Ma, Minglai Fu
For the first time, an integrated green technology by coupling functional nanoscale zero-valent iron (NZVI) with ultrasound (US) was innovatively developed for the enhanced decolorization of malachite green (MG) and methylene blue (MB). The functional NZVI (TP-Fe) was successfully fabricated via a facile, one-step and environmentally-benign approach by directly introducing high pure tea polyphenol (TP), where TP contenting abundant epicatechin was employed as reductant, dispersant and capping agent. Note that neither additional extraction procedure nor protection gas was needed during the entire synthesis process...
January 2017: Chemosphere
Suthida Pheenithicharoenkul, Anchana Panichuttra
This study aimed to investigate the effect of epigallocatechin-3-gallate (EGCG) from green tea extract on the push out bond strength of an epoxy resin sealer to root dentin. Seventy single root canal premolars were decoronated and instrumented. The roots were randomly irrigated with different final irrigation protocols (n=16): 17%EDTA (EDTA), 17%EDTA followed by 2.5%NaOCl (EDTA+NaOCl), 17%EDTA followed by 1 mg/mL EGCG (EDTA+EGCG) and 1 mg/mL EGCG (EGCG). Other six root canals were received only 2.5%NaOCl as a control group...
September 29, 2016: Dental Materials Journal
Victor Navarro, Ikhlas Khan, Einar Björnsson, Leonard B Seeff, Jose Serrano, Jay H Hoofnagle
Herbal and dietary supplements (HDS) are used increasingly both in the United States and worldwide and HDS induced liver injury in the U.S. has increased proportionally. Current challenges in the diagnosis and management of HDS-induced liver injury were the focus of a 2-day research symposium sponsored by the American Association for the Study of Liver Disease and the National Institutes of Health. HDS-induced liver injury now accounts for 20% of cases of hepatotoxicity in the United States based on research data...
September 27, 2016: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
Tandeka Unathi Magcwebeba, Sylvia Riedel, Sonja Swanevelder, Pieter Swart, Dalene De Beer, Elizabeth Joubert, Wentzel Christoffel Andreas Gelderblom
OBJECTIVES: The relationship between polyphenol constituents, antioxidant properties of aqueous and methanol extracts of green tea (Camellia sinensis), the herbal teas, rooibos (Aspalathus linearis) and honeybush (Cyclopia spp.), against skin cell viability was investigated in vitro. METHODS: The effect of extracts, characterised in terms of polyphenol content and antioxidant properties, on cell viability of premalignant, normal and malignant skin cells was determined...
September 27, 2016: Journal of Pharmacy and Pharmacology
Carola Biancalani, Matteo Cerboneschi, Francesco Tadini-Buoninsegni, Margherita Campo, Arianna Scardigli, Annalisa Romani, Stefania Tegli
Protection of plants against bacterial diseases still mainly relies on the use of chemical pesticides, which in Europe correspond essentially to copper-based compounds. However, recently plant diseases control is oriented towards a rational use of molecules and extracts, generally with natural origin, with lower intrinsic toxicity and a reduced negative environmental impact. In this work, polyphenolic extracts from vegetable no food/feed residues of typical Mediterranean crops, as Olea europaea, Cynara scolymus, and Vitis vinifera were obtained and their inhibitory activity on the Type Three Secretion System (TTSS) and the Quorum Sensing (QS) of the Gram-negative phytopathogenic bacterium Pseudomonas savastanoi pv...
2016: PloS One
Sadaf Lebaschi, Malak Hekmati, Hojat Veisi
The present study was conducted to synthesize palladium nanoparticles (Pd NPs) through a facile and green route using non-toxic and renewable natural black tea leaves (Camellia sinensis) extract, as the reducing and stabilizing agent. The as-prepared Pd@B.tea NPs catalyst was characterized by UV-vis spectroscopy, X-ray diffraction (XRD), fourier transformed infrared spectroscopy (FT-IR), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM) and energy dispersive X-ray spectroscopy (EDS)...
January 1, 2017: Journal of Colloid and Interface Science
Jackson M Muema, Joel L Bargul, Steven G Nyanjom, James M Mutunga, Sospeter N Njeru
BACKGROUND: Anopheles arabiensis and A. gambiae (sensu stricto) are the most prolific Afrotropical malaria vectors. Population control efforts of these two vectors have been hampered by extremely diverse larval breeding sites and widespread resistance to currently available insecticides. Control of mosquito larval stages using bioactive compounds of plant origin has the potential to suppress vector populations leading to concomitant reduction in disease transmission rates. In this study, we evaluated the efficacy of Camellia sinensis crude leaf extract and its fraction against the larvae of A...
2016: Parasites & Vectors
Cordelia A Running, John E Hayes
Saliva is becoming an increasingly useful research material across multiple fields of inquiry, including biomedical, dental, psychological, nutritional, and food choice research. However, both the flow rate and protein composition of stimulated saliva differ as a function of the collection method. We hypothesized that the context in which a stimulus is presented to participants may alter salivation via top down cognitive effects and/or behavioral changes (i.e., spitting efficiency). We presented participants with one stimulus (commercially available green tea) in two distinct contexts, once where the tea was described as a food item ("tea") and once where it was described as a disgusting non-food item ("rabbit hair extract")...
September 20, 2016: Physiology & Behavior
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