Mariana da Silva Bonatto, Geórgia da Silva Feltran, Thamires Prazeres Barbosa, Davisson Alves Pereira, Samara de Souza Santos, Pedro Gomes Junqueira Mendes, Roberto Sales E Pessoa, Fábio José Barbosa Bezerra, Willian Fernando Zambuzzi, Guilherme José Pimentel Lopes de Oliveira
This study evaluates the effects of a green tea (Camellia sinensis) and hyaluronic acid gel on fibroblast activity and alveolar bone repair following third molar extractions. By examining the gene expression related to cell survival, proliferation, and angiogenesis, the study bridges in vitro findings with clinical outcomes in a split-mouth randomized trial. Human fibroblasts were exposed to the treatment gel, analysing gene expression through RT-qPCR. Twenty participants undergoing bilateral third molar extractions received the test gel on one side and a placebo on the other...
March 26, 2024: Scientific Reports