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JOURNAL ARTICLE
Muhammad Muhammad, Maher Saifo, Majd Aljamali, Mousa Alali, Khaled M Ghanem
INTRODUCTION: Polymorphisms in NUDT15 may result in differences in mercaptopurine-induced toxicity. This study aimed to identify the frequency of the NUDT15 (c.415C>T; rs116855232) polymorphism and investigate the effect of this polymorphism on mercaptopurine-induced toxicity in a population of Syrian patients with childhood acute lymphoblastic leukemia (ALL). METHODS: This is a retrospective study that included children with ALL reaching at least 6 months of maintenance therapy...
2024: Frontiers in Oncology
#22
JOURNAL ARTICLE
Hidar Alibrahim, Sarya Swed, Haidara Bohsas, Yasmeen Abouainain, Nagham Jawish, Rehab Diab, Angela Ishak, Heba Haj Saleh, Mohamad Nour Nasif, Rahaf Arafah, Wajih Abboud Abboud, Asma'a Horan Suliman, Bisher Sawaf, Wael Hafez
BACKGROUND: Vitamin D deficiency is an importance preventable problem in the global and associates with lack levels of awareness about vitamin D. According to prior studies, in the Arab world, there is low of knowledge and awareness toward vitamin D deficiency. The target of our study is evaluating the knowledge level about vitamin D deficiency and determining the associated factors with levels of awareness of its. METHOD: This online cross-sectional study was performed in Syria between 25 February to 29 March 2023 to assess the levels of knowledge about vitamin D deficiency among general Syrian population...
April 1, 2024: BMC Public Health
#23
Nafiza Martini, Maha Al Haj Kaddour, Mouna Baddoura, Mulham Jarjanazi, Jaber Mahmoud
A gastric ulcer is a tear in the stomach lining that manifests as abdominal pain, nausea, vomiting, and weight loss. Its occurrence is lesser in children as compared to adults and its incidence in children ranges between 2% and 8%. Helicobacter pylori and nonsteroidal anti-inflammatory drugs are the most common causes of gastric ulcers. In our case, we report a 2.5-month-old male who presented with severe pallor, hematemesis, and melena with normal weight gain. The patient's mother was infected with COVID-19 a month ago and recovered within 5 days but kept using aspirin and nonsteroidal anti-inflammatory drugs for a month during breastfeeding...
2024: SAGE Open Medical Case Reports
#24
JOURNAL ARTICLE
Jameel Soqia, Jamal Ataya, Rakan Saadoun, Lujain Nahas, Albaraa Yazbek, Mohammed Al-Shafie, Hamdah Hanifa, Muhialdein Dakak, Ahmad Walid Izzat, Mohammad Bashar Izzat
OBJECTIVE: This study explored how the Syrian crisis, training conditions, and relocation influenced the National Medical Examination (NME) scores of final-year medical students. METHODS: Results of the NME were used to denote the performance of final-year medical students between 2014 and 2021. The NME is a mandatory standardised test that measures the knowledge and competence of students in various clinical subjects. We categorised the data into two periods: period-I (2014-2018) and period-II (2019-2021)...
March 28, 2024: Medical Education
#25
JOURNAL ARTICLE
Kamal Fahmy, Quamrul Hasan, Md Sharifuzzaman, Yvan Hutin
Yearly national immunization coverage reporting does not measure performance at the subnational level throughout the year and conceals inequalities within countries. We analyzed subnational immunization coverage from seven high-priority countries in our region. We analyzed subnational, monthly immunization data from seven high-priority countries. Five were Gavi eligible (i.e., Afghanistan, Pakistan, Somalia, Syria, and Yemen); these are countries that according to their low income are eligible for support from the Global Alliance on Vaccine and Immunization, while Iraq and Jordan were included because of a recent decrease in immunization coverage and contribution to the regional number of under and unimmunized children...
March 8, 2024: Vaccines
#26
JOURNAL ARTICLE
Grzegorz Dąbrowski, Sylwester Czaplicki, Iwona Konopka
Nigella sativa L. (black cumin) is one of the most investigated medicinal plants in recent years. Volatile compounds like thymoquinone and unsaponifiable lipid compounds are crucial functional components of this oil. Unfortunately, the composition of oils and their quality indicators are ambiguous both in terms of identified compounds and value ranges. Thirteen oils were extracted with hexane from black cumin seeds grown in India, Syria, Egypt, and Poland and analyzed for their fatty acid composition, unsaponifiable compound content and volatile compounds...
March 19, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
#27
JOURNAL ARTICLE
Younes A Khadour, Bashar M Ebrahem, Weaam Alhatem, Engo Ovone Yanne, Fater A Khadour
Diabetes mellitus (DM) is a prevalent disorder that affects the endocrine and metabolic systems. Among the various complications associated with DM, diabetic bladder dysfunction (DBD) is the most frequently occurring genitourinary complication. The presence of DBD can lead to complications that affect the upper urinary tract, significantly impacting the quality of life for individuals with DM. Therefore, it is crucial to identify early risk factors for DBD and predict its onset. Given the absence of studies involving bladder dysfunction in patients with type 2 diabetes mellitus (T2DM) in Syria, this study aims to examine the risk factors associated with bladder dysfunction in T2DM patients and develop a predictive model to identify DBD early...
March 26, 2024: Scientific Reports
#28
JOURNAL ARTICLE
Mariana Helou, Yara Mouawad, Fadi El Ters, Rola Husni
After the beginning of the Syrian crisis, increased rates of infectious diseases were reported. Lebanon, a neighboring country with a major socioeconomic crisis, witnessed a measles outbreak since July 2023, with 519 reported suspected cases. Half of the cases were under 5 y of age, most of them were unvaccinated. The mass displacement of refugees from conflict areas in Syria to Lebanon and the low vaccination coverage have made the situation more challenging. Further efforts are required in Lebanon to address identified gaps to prevent or at least better control future outbreaks...
March 25, 2024: Disaster Medicine and Public Health Preparedness
#29
JOURNAL ARTICLE
Alexander N Hasenstab
No abstract text is available yet for this article.
March 2024: Medicine, Conflict, and Survival
#30
JOURNAL ARTICLE
Helen M Faddy, Carla Osiowy, Brian Custer, Michael Busch, Susan L Stramer, Melinda M Dean, Jessika Acutt, Elvina Viennet, Thijs van de Laar, Wai-Chiu Tsoi, Claire Styles, Phil Kiely, Angelo Margaritis, So-Yong Kwon, Yan Qiu, Xuelian Deng, Antoine Lewin, Signe Winther Jørgensen, Christian Erikstrup, David Juhl, Silvia Sauleda, Bernardo Armando Camacho Rodriguez, Lisbeth Jennifer Catherine Soto Coral, Paula Andrea Gaviria García, Sineenart Oota, Sheila F O'Brien, Silvano Wendel, Emma Castro, Laura Navarro Pérez, Heli Harvala, Katy Davison, Claire Reynolds, Lisa Jarvis, Piotr Grabarczyk, Aneta Kopacz, Magdalena Łętowska, Niamh O'Flaherty, Fiona Young, Padraig Williams, Lisa Burke, Sze Sze Chua, An Muylaert, Isabel Page, Ann Jones, Christoph Niederhauser, Marion Vermeulen, Syria Laperche, Pierre Gallian, Masahiro Satake, Marcelo Addas-Carvalho, Sebastián Blanco, Sandra V Gallego, Axel Seltsam, Marijke Weber-Schehl, Arwa Z Al-Riyami, Khuloud Al Maamari, Fatma Ba Alawi, Hem Chandra Pandey, Rochele Azevedo França, Richard Charlewood
BACKGROUND AND OBJECTIVES: Nucleic acid-amplification testing (NAT) is used for screening blood donations/donors for blood-borne viruses. We reviewed global viral NAT characteristics and NAT-yield confirmatory testing used by blood operators. MATERIALS AND METHODS: NAT characteristics and NAT-yield confirmatory testing used during 2019 was surveyed internationally by the International Society of Blood Transfusion Working Party Transfusion-Transmitted Infectious Diseases...
March 22, 2024: Vox Sanguinis
#31
JOURNAL ARTICLE
Kumarse Nazari, Ezgi Kurtulus, Handan Kavaz, Rola El Amil, Tina Thach, Hakan Hekiman, Gurkan Basbagci, Emine Burcu Turgay, Doaa R El-Naggar, Walid El-Orabey, Reda I Omara, Kholoud M Alananbeh, Ayed Al-Abdallat, Monther M Tahat, Khaled Heimoun, Ghias Mhairy, Samer Abau Ghorrah
Over the last decade, field assessments of the yellow rust differential lines for resistance genes Yr10 and Yr24 and race analysis in the Middle East have demonstrated efficient yellow rust control by Yr10 and Yr24 (=Yr26). Yellow rust samples collected during 2018-21 in Central West Asia & North and sub-Saharan Africa underwent race analysis at the Regional Cereal Rust Research Center in Izmir, Türkiye. The infected leaf segments were subjected to rehydration at 20°C for three hours. Subsequently, the leaf segments were rubbed on the first leaves of seedlings of susceptible cultivar Morocco...
March 21, 2024: Plant Disease
#32
JOURNAL ARTICLE
Sarya Swed, Haidara Bohsas, Hidar Alibrahim, Khaled Albakri, Mohammed Amir Rais, Mohammad Badr Almoshantaf, Wael Hafez, Yasmeen Abouainain, Bisher Sawaf, Lamees Alshareef, Zain Alabdeen Ayman Othman, Ibrahim Elbialy, Hekmieh Manad, Youmna Faheem, Steffi John, Jalal Alshareef, Lana Sheet, Amine Rakab
BACKGROUND: Palliative care alleviates pain and enhances the quality of life of patients with life-threatening illnesses. Training programs are required to provide patients with proper care and advance their health because the expertise of healthcare personnel in palliative care is inadequate. AIM: We aimed to assess healthcare professionals' knowledge of palliative care because palliative care programs are infrequently used in Syria. METHODS: An online cross-sectional study was conducted between July 24, 2022, and August 28, 2022, to assess palliative care knowledge and applications among Syrian healthcare workers...
February 2024: Curēus
#33
JOURNAL ARTICLE
Ilker Taşdemir, Muhammed Emin Boylu, Hızır Aslıyüksek, Sefa Saygılı, Kayıhan Oğuz Karamustafalıoğlu
This study aimed to scrutinize the characteristics of immigrant and refugee offenders within our institution, focusing on factors such as immigrant status, country of birth, duration of residence in Turkey, as well as psychiatric, socio-demographic, and criminal profiles. The data were obtained through a retrospective examination of case records referred to the Observation Department of the Council of Forensic Medicine for the assessment of criminal responsibility between 2017 and 2022. The study categorized the cases into two groups: refugees and immigrants, comprising 35 and 22 offenders, respectively...
March 20, 2024: International Journal of Offender Therapy and Comparative Criminology
#34
JOURNAL ARTICLE
Bahadır Karaca, Mehmet Kemal Emem, Burak Çelik, Nurdan Yılmaz Şahin
BACKGROUND: There is a need for studies evaluating prognostic scoring systems in mass trauma patients in conflict regions to predict patient prognosis for emergency surgical prioritization. In this study, we aimed to evaluate scoring systems such as the Revised Trauma Score (RTS), Injury Severity Score (ISS), and Trauma and Injury Severity Score (TRISS) in trauma patients admitted due to mass trauma in Northern Syria. METHODS: This study was a retrospective evaluation of patients admitted due to mass trauma to the emergency departments of hospitals in Northern Syria...
March 2024: Turkish Journal of Trauma & Emergency Surgery: TJTES
#35
JOURNAL ARTICLE
Hidar Alibrahim, Haidara Bohsas, Sarya Swed, Khaled Albakri, Yossef H AbdeQadir, Sara Ramadan, Lazaward Kazan, Heba Haj Saleh, Fatema Ali Asgar Tashrifwala, Mohamad Al Ibrahim, Sabine Tayfour, Touka Abo Alsel, Abdullah Alnehlawi, Ubaid Khan, Ashraf N B Boktor, Ibrahim Elbialy, Hekmieh Manad, Reem Rizk Abazid, Wael Hafez
INTRODUCTION: Liver disease is among the leading causes of global mortality and morbidity. Given their substantial impact on public health, raising awareness about liver diseases is paramount for their prevention and effective management. This study aimed to evaluate the knowledge, awareness, attitudes, and behaviors of Syrians regarding liver health, chronic liver disorders, and their associated serious and irreversible complications. METHODS: We conducted a cross-sectional study encompassing the adult Syrian population between August 25 and September 29, 2023, excluding non-Syrians and individuals below the age of 18 years...
February 2024: Curēus
#36
JOURNAL ARTICLE
Martini Nafiza, Almasri Imad-Addin, Almouallem Mohamad Moamen, Khaled Raghad, Hamdar Hussein, Nahle Ali Alakbar, Mahmod Jaber
INTRODUCTION: Accidental ingestion of caustic agents poses a significant concern in pediatric emergency departments globally. It is a growing public health concern in low-to-middle income countries, which often lack comprehensive data reporting. This study examines high doses of corticosteroid treatment outcomes of caustic ingestion injuries in Syrian pediatric patients, addressing clinical features, and associated variables. METHODS AND MATERIALS: A retrospective observational study was conducted at University Pediatric Hospital from January 2016 to January 2019...
2024: SAGE Open Medicine
#37
JOURNAL ARTICLE
Eman Shhada, Hussein Hamdar, Ali Alakbar Nahle, Diana Mourad, Basheer Khalil, Sawssan Ali
OBJECTIVE: Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 is a rare and serious medical condition. This study aims to review the clinical presentation, laboratory parameters, outcomes, and management of MIS-C cases in a pediatric hospital in Syria. METHODS: This retrospective observational study aimed to investigate MIS-C between May 2020 and October 2021. Data collection involved extracting information from medical records, and patients were identified based on the case definition established by the World Health Organization (WHO)...
March 15, 2024: BMC Infectious Diseases
#38
JOURNAL ARTICLE
Xing Li, Sigurjón Jónsson, Shaozhuo Liu, Zhangfeng Ma, Nicolás Castro-Perdomo, Simone Cesca, Frédéric Masson, Yann Klinger
Reported fault slip rates, a key quantity for earthquake hazard and risk analyses, have been inconsistent for the northern Dead Sea fault (DSF). Studies of offset geological and archeological structures suggest a slip rate of 4 to 6 millimeters per year, consistent with the southern DSF, whereas geodetic slip-rate estimates are only 2 to 3 millimeters per year. To resolve this inconsistency and overcome limited access to the northern DSF in Syria, we here use burst-overlap interferometric time-series analysis of satellite radar images to provide an independent slip-rate estimate of ~2...
March 15, 2024: Science Advances
#39
Mouhammed Sleiay, Bilal Sleiay, Douha Albaroudi, Hasan Alsmoudi, Mohammad Ali Abshi, Mohammed Alaswad, Abdulazez Sleiay, Osama Arabi
This case highlights the significance of maintaining clinical suspicion for CPBs in adults presenting with SBO. Early surgical intervention, offering both diagnosis and treatment, is essential for managing this rare cause of SBO. Increased clinical awareness of CPBs will help ensure they are considered in the differential diagnosis of adult patients with bowel obstruction.
March 2024: Clinical Case Reports
#40
JOURNAL ARTICLE
Sami Alasfar, Hani Alashavi, Khaled Hajj Nasan, Abd Aljabbar Haj Mousa, Camila Polinori, Valerie Luyckx, Mohamed Sekkarie, Saleh Kaysi, Lina Murad, Gilbert M Burnham
INTRODUCTION: Providing hemodialysis to patients with kidney failure (KF) in conflict-affected areas poses a significant challenge. Achieving and sustaining reasonable quality hemodialysis operations in such regions necessitates a comprehensive approach. METHODS: In the conflict area of Northwest (NW) Syria, a 3-phase project was initiated to address the quality of hemodialysis operations. The assessment phase involved the examination of infection prevention and control (IPC) protocols, staff training, medical protocols, individualized hemodialysis prescriptions, and laboratory testing capabilities...
March 2024: KI Reports
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