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https://www.readbyqxmd.com/read/28749494/two-intensified-fluorescence-colors-switching-achieved-by-branched-dye-nanoaggregates
#1
Ge Ding, Yao Lu, Jihong Su, Xiaozhuan Qin, Ziping Luo, Fang Gao, Lingyun Chen, Hongru Li
In this study, a variety of branched target dyes containing double internal proton transfer segments were synthesized. For comparison, some linear analogs including a single internal proton transfer part were synthesized. The corresponding reference molecules lacking proton transfer segments were also prepared. The properties and aggregation modes of these dye aggregates were investigated on the basis of scanning electron microscopy images, transmission electron microscopy images, dynamic light scattering, X-ray diffraction, UV/visible absorption spectra and fluorescence emission spectra...
July 27, 2017: Nanoscale
https://www.readbyqxmd.com/read/28749332/human-myiasis-caused-by-the-reindeer-warble-fly-hypoderma-tarandi-case-series-from-norway-2011-to-2016
#2
Jörgen Landehag, Andreas Skogen, Kjetil Åsbakk, Boris Kan
Hypoderma tarandi causes myiasis in reindeer and caribou (Rangifer tarandus spp.) in most northern hemisphere regions where these animals live. We report a series of 39 human myiasis cases caused by H. tarandi in Norway from 2011 to 2016. Thirty-two were residents of Finnmark, the northernmost county of Norway, one a visitor to Finnmark, and six lived in other counties of Norway where reindeer live. Clinical manifestations involved migratory dermal swellings of the face and head, enlargement of regional lymph nodes, and periorbital oedema, with or without eosinophilia...
July 20, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28749304/investigation-of-enrofloxacin-associated-retinal-toxicity-in-nondomestic-felids
#3
Kim M Newkirk, L Kathryn Beard, Xiaocun Sun, Edward C Ramsay
Enrofloxacin is known to cause retinal toxicity in domestic cats. The hallmark lesion of enrofloxacin-associated retinal toxicity in domestic cats is thinning of the outer nuclear layer of the retina. Enrofloxacin is commonly used to treat bacterial infections in nondomestic felids because of its action against a wide spectrum of bacteria and the ability for it to be given orally. No previous studies have investigated the potential retinal toxicity of enrofloxacin in nondomestic felids. This retrospective study evaluated 81 eyes from 14 lions ( Panthera leo ) and 33 tigers ( Panthera tigris ) that had been enucleated or collected postmortem...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749279/effects-of-tramadol-on-the-minimum-anesthetic-concentration-of-isoflurane-in-white-eyed-parakeets-psittacara-leucophthalmus
#4
André Escobar, Rozana Wendler da Rocha, Monica Midon, Ricardo Miyasaka de Almeida, Darcio Zangirolami Filho, Karin Werther
The aim of this study was to determine the minimum anesthetic concentration (MAC) of isoflurane, and to investigate if tramadol changes the isoflurane MAC in white-eyed parakeets (Psittacara leucophthalmus). Ten adult birds weighing 157 ± 9 g were anesthetized with isoflurane in oxygen under mechanical ventilation. Isoflurane concentration for the first bird was adjusted to 2.2%, and after 15 min an electrical stimulus was applied in the thigh area to observe the response (movement or nonmovement). Isoflurane concentration for the subsequent bird was increased by 10% if the previous bird moved, or decreased by 10% if the previous bird did not move...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28748990/-clinical-features-of-patients-with-basedow-graves-disease-seen-at-a-university-hospital
#5
Alejandra Lanas, Patricia Díaz, Daniela Eugenin, Franco González, Pía Cid, Francisco Cordero, Verónica Araya, Claudio Liberman, Marcela Barberan, Patricio Gac, Neil Saldías, Pedro Pineda
BACKGROUND: Basedow Graves disease (BGD) is the leading cause of hyperthyroidism. The characteristics of patients seen at a university hospital may differ from those described in the general population. AIM: To describe the clinical features of patients with BGD seen at a university hospital. MATERIAL AND METHODS: Review of medical records of all patients seen at our hospital between 2009 and 2014 with the diagnosis of thyrotoxicosis, hyperthyroidism or BGD...
April 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28748985/brief-update-on-diabetes-for-general-practitioners
#6
A Barquilla García
Diabetes includes a group of metabolic disorders in which there is hyperglycemia. This can be due to impaired insulin secretion, insulin action or both. Chronic hyperglycemia is associated with serious long-term complications in several organs, especially in the eyes, kidneys, nerves, heart and blood vessels. In our country this disorder affects 13.8% of the population. There are several types of diabetes although most patients suffer type 2 diabetes. We set out to review the diagnostic process, screening recommendations, prevention strategies, initial assessment upon diagnosis, therapeutic targets regarding both blood glucose levels and the other vascular risk factors while also considering healthy lifestyles and brief references to medications recommended in each section...
December 2017: Revista Española de Sanidad Penitenciaria
https://www.readbyqxmd.com/read/28748642/noonan-syndrome-in-diverse-populations
#7
Paul Kruszka, Antonio R Porras, Yonit A Addissie, Angélica Moresco, Sofia Medrano, Gary T K Mok, Gordon K C Leung, Cedrik Tekendo-Ngongang, Annette Uwineza, Meow-Keong Thong, Premala Muthukumarasamy, Engela Honey, Ekanem N Ekure, Ogochukwu J Sokunbi, Nnenna Kalu, Kelly L Jones, Julie D Kaplan, Omar A Abdul-Rahman, Lisa M Vincent, Amber Love, Khadija Belhassan, Karim Ouldim, Ihssane El Bouchikhi, Anju Shukla, Katta M Girisha, Siddaramappa J Patil, Nirmala D Sirisena, Vajira H W Dissanayake, C Sampath Paththinige, Rupesh Mishra, Eva Klein-Zighelboim, Bertha E Gallardo Jugo, Miguel Chávez Pastor, Hugo H Abarca-Barriga, Steven A Skinner, Eloise J Prijoles, Eben Badoe, Ashleigh D Gill, Vorasuk Shotelersuk, Patroula Smpokou, Monisha S Kisling, Carlos R Ferreira, Leon Mutesa, Andre Megarbane, Antonie D Kline, Amy Kimball, Emmy Okello, Peter Lwabi, Twalib Aliku, Emmanuel Tenywa, Nonglak Boonchooduang, Pranoot Tanpaiboon, Antonio Richieri-Costa, Ambroise Wonkam, Brian H Y Chung, Roger E Stevenson, Marshall Summar, Kausik Mandal, Shubha R Phadke, María G Obregon, Marius G Linguraru, Maximilian Muenke
Noonan syndrome (NS) is a common genetic syndrome associated with gain of function variants in genes in the Ras/MAPK pathway. The phenotype of NS has been well characterized in populations of European descent with less attention given to other groups. In this study, individuals from diverse populations with NS were evaluated clinically and by facial analysis technology. Clinical data and images from 125 individuals with NS were obtained from 20 countries with an average age of 8 years and female composition of 46%...
July 27, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28748304/the-eye-fluke-tylodelphys-clavata-affects-prey-detection-and-intraspecific-competition-of-european-perch-perca-fluviatilis
#8
Jenny Carolina Vivas Muñoz, Georg Staaks, Klaus Knopf
Parasites that occupy the eyes of fish have the potential to affect visual perception and consequently alter the host's behaviour, as these organs provide information about their surroundings. In an experimental study, the feeding behaviour of European perch (Perca fluviatilis) infested with the eye fluke Tylodelphys clavata was examined. The results showed that an individual's ability to identify and approach food items was negatively affected by the infestation intensity of T. clavata. Additionally, the foraging success of an individual was reduced in competition with another, less heavily infested conspecific, when the same food resource was exploited...
July 27, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28748109/un-explained-visual-loss-following-silicone-oil-removal-results-of-the-pan-american-collaborative-retina-study-pacores-group
#9
Jose A Roca, Lihteh Wu, Maria Berrocal, Francisco Rodriguez, Arturo Alezzandrini, Gustavo Alvira, Raul Velez-Montoya, Hugo Quiroz-Mercado, J Fernando Arevalo, Martín Serrano, Luiz H Lima, Marta Figueroa, Michel Farah, Giovanna Chico
PURPOSE: To report the incidence and clinical features of patients that experienced un-explained visual loss following silicone oil (SO) removal. METHODS: Multicenter retrospective study of patients that underwent SO removal during 2000-2012. Visual loss of ≥2 lines was considered significant. RESULTS: A total of 324 eyes of 324 patients underwent SO removal during the study period. Forty two (13%) eyes suffered a significant visual loss following SO removal...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/28748060/a-case-of-attempted-bilateral-self-enucleation-in-a-patient-with-bipolar-disorder
#10
Hannah Muniz Castro, John Alvarez, Robert G Bota, Marc Yonkers, Jeremiah Tao
Attempted and completed self-enucleation, or removal of one's own eyes, is a rare but devastating form of self-mutilation behavior. It is often associated with psychiatric disorders, particularly schizophrenia, substance induced psychosis, and bipolar disorder. We report a case of a patient with a history of bipolar disorder who gouged his eyes bilaterally as an attempt to self-enucleate himself. On presentation, the patient was manic with both psychotic features of hyperreligous delusions and command auditory hallucinations of God telling him to take his eyes out...
March 22, 2017: Mental Illness
https://www.readbyqxmd.com/read/28747876/structural-correlates-of-reading-the-mind-in-the-eyes-in-autism-spectrum-disorder
#11
Wataru Sato, Shota Uono, Takanori Kochiyama, Sayaka Yoshimura, Reiko Sawada, Yasutaka Kubota, Morimitsu Sakihama, Motomi Toichi
Behavioral studies have shown that individuals with autism spectrum disorder (ASD) have impaired ability to read the mind in the eyes. Although this impairment is central to their social malfunctioning, its structural neural correlates remain unclear. To investigate this issue, we assessed Reading the Mind in the Eyes Test, revised version (Eyes Test) and acquired structural magnetic resonance images in adults with high-functioning ASD (n = 19) and age-, sex- and intelligence quotient-matched typically developing (TD) controls (n = 19)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28747871/age-and-glaucoma-related-characteristics-in-retinal-nerve-fiber-layer-and-choroid-localized-morphometrics-and-visualization-using-functional-shapes-registration
#12
Sieun Lee, Morgan L Heisler, Karteek Popuri, Nicolas Charon, Benjamin Charlier, Alain Trouvé, Paul J Mackenzie, Marinko V Sarunic, Mirza Faisal Beg
Optical coherence tomography provides high-resolution 3D imaging of the posterior segment of the eye. However, quantitative morphological analysis, particularly relevant in retinal degenerative diseases such as glaucoma, has been confined to simple sectorization and averaging with limited spatial sensitivity for detection of clinical markers. In this paper, we present point-wise analysis and visualization of the retinal nerve fiber layer and choroid from cross-sectional data using functional shapes (fshape) registration...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28747743/food-protective-effects-of-3-methylbenzaldehyde-derived-from-myosotis-arvensis-and-its-analogues-against-tyrophagus-putrescentiae
#13
Jun-Hwan Park, Na-Hyun Lee, Young-Cheol Yang, Hoi-Seon Lee
The potential abilities of 3-methylbenzaldehyde derived from Myosotis arvensis oil and its structural analogues to act as new acaricide and mite kit (mite color deformation) against Tyrophagus putrescentiae (Schrank) were evaluated in the present study. Based on the LD50 values, 2,4,5-trimethylbenzaldehyde (0.78 μg/cm(3)) had highest vapor action against T. putrescentiae, followed by 2,4-methylbenzaldehyde (1.14 μg/cm(3)), 2,5-dimethylbenzaldehyde (1.29 μg/cm(3)), 2-methylbenzaldehyde (1.32 μg/cm(3)), 2,3-dimethylbenzaldehyde (1...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747691/the-absence-that-makes-the-difference-choroidal-abnormalities-in-legius-syndrome
#14
Arianna Tucci, Veronica Saletti, Francesca Menni, Claudia Cesaretti, Giulietta Scuvera, Silvia Esposito, Giulia Melloni, Susanna Esposito, Donatella Milani, Cristina Cereda, Mario Cigada, Laura Tresoldi, Francesco Viola, Federica Natacci
Neurofibromatosis type 1 (NF1) is an hereditary disorder characterized by abnormal proliferation of multiple tissues of neural crest origin, and presents mainly with multiple café-au-lait macules, axillary freckling and neurofibromas. Choroidal involvement in NF1 patients has been studied, thanks to the development of non-invasive tools such as infrared monochromatic light during fundus examination, which showed bright patchy lesions consistent with choroidal nodules. Choroidal abnormalities identified with near-infrared reflectance have reported with a frequency of up to 100% in NF1, and have been recently been proposed as a novel diagnostic criterion for NF1...
July 27, 2017: Journal of Human Genetics
https://www.readbyqxmd.com/read/28747634/changes-of-corneal-tomography-in-patients-with-congenital-blepharoptosis
#15
Tiepei Zhu, Xin Ye, Peifang Xu, Jingyi Wang, Huina Zhang, Hailong Ni, Zhaoan Su, Juan Ye
The study aimed to evaluate the effect of drooped eyelid on corneal tomography in congenital blepharoptosis patients. Sixty-four patients with congenital blepharoptosis and 64 age- and sex- matched healthy subjects were included. According to the eyelid margin to corneal light reflex distance (MRD), eyes with congenital blepharoptosis were categorized as mild, moderate, or severe. The eyes were scanned using the rotating Scheimpflug camera. Increased topometric parameters were observed in moderate and severe blepharoptosis...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747621/evaluation-of-biomechanical-changes-in-myopia-patients-with-unsatisfactory-corneas-after-femto-second-laser-in-situ-keratomileusis-fs-lasik-concurrent-with-accelerated-corneal-collagen-cross-linking-using-corvis-st-two-year-follow-up-results
#16
Weiwei Xu, Ye Tao, Liqiang Wang, Yifei Huang
BACKGROUND Some myopia patients with unsatisfactory corneas consider corneal refractive surgery for different reasons. Accelerated corneal collagen crosslinking (ACXL) is an effective method to enhance the resistance of the cornea. The present investigation was designed to evaluate the changes of biomechanical properties in patients with myopia and thin corneas after femtosecond-laser in situ keratomileusis (FS-LASIK) concurrent with ACXL. MATERIAL AND METHODS A prospective study was designed. A total of 22 eyes of 11 myopia astigmatism patients with unsatisfactory corneas were enrolled...
July 27, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28747466/network-activity-influences-the-subthreshold-and-spiking-visual-responses-of-pyramidal-neurons-in-the-three-layer-turtle-cortex
#17
Nathaniel Caleb Wright, Ralf Wessel
A primary goal of systems neuroscience is to understand cortical function, which typically involves studying spontaneous and stimulus-modulated cortical activity. Mounting evidence suggests a strong and complex relationship exists between the ongoing and stimulus-modulated cortical state. To date, most work in this area has been based on spiking in populations of neurons. While advantageous in many respects, this approach is limited in scope; it records the activity of a minority of neurons, and gives no direct indication of the underlying subthreshold dynamics...
July 26, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28747401/influence-of-scene-structure-and-content-on-visual-search-strategies
#18
Tatiana A Amor, Mirko Luković, Hans J Herrmann, José S Andrade
When searching for a target within an image, our brain can adopt different strategies, but which one does it choose? This question can be answered by tracking the motion of the eye while it executes the task. Following many individuals performing various search tasks, we distinguish between two competing strategies. Motivated by these findings, we introduce a model that captures the interplay of the search strategies and allows us to create artificial eye-tracking trajectories, which could be compared with the experimental ones...
July 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28747368/fusarium-keratitis-in-germany
#19
Grit Walther, Serena Stasch, Kerstin Kaerger, Axel Hamprecht, Mathias Roth, Oliver A Cornely, Gerd Geerling, Colin R Mackenzie, Oliver Kurzai, Marie von Lilienfeld-Toal
Fusarium keratitis is a destructive eye infection that is difficult to treat and which results in poor outcome. In the tropical and subtropical areas the infection is relatively common and associated with trauma or chronic eye diseases. However, in recent years, an increased incidence has been reported in temperate climate regions. At the German National Reference Center, we observed a steady increase in case numbers since 2014. Here, we present the first German case series of eye infections with Fusarium spp...
July 26, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28747198/population-based-prevalence-survey-of-follicular-trachoma-and-trachomatous-trichiasis-in-the-casamance-region-of-senegal
#20
Emma M Harding-Esch, Julbert Kadimpeul, Boubacar Sarr, Awa Sane, Souleymane Badji, Mass Laye, Ansumana Sillah, Sarah E Burr, David MacLeod, Anna R Last, Martin J Holland, David C Mabey, Robin L Bailey
BACKGROUND: Trachoma, caused by ocular infection with Chlamydia trachomatis, is the leading infectious cause of blindness worldwide. We conducted the first population-based trachoma prevalence survey in the Casamance region of Senegal to enable the Senegalese National Eye Care Programme (NECP) to plan its trachoma control activities. The World Health Organization (WHO) guidelines state that any individual with trachomatous trichiasis (TT) should be offered surgery, but that surgery should be prioritised where the prevalence is >0...
July 26, 2017: BMC Public Health
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