keyword
https://read.qxmd.com/read/38536530/the-paradox-of-mri-for-breast-cancer-screening-high-risk-and-dense-breasts-available-evidence-and-current-practice
#21
REVIEW
Francesco Sardanelli, Veronica Magni, Gabriele Rossini, Fleur Kilburn-Toppin, Nuala A Healy, Fiona J Gilbert
In the mid-1990s, the identification of BRCA1/2 genes for breast cancer susceptibility led to testing breast MRI accuracy in screening women at increased risk. From 2000 onwards, ten intraindividual comparative studies showed the marked superiority of MRI: the sensitivity ranged 25-58% for mammography, 33-52% for ultrasound, 48-67% for mammography plus ultrasound, and 71-100% for MRI; specificity 93-100%, 91-98%, 89-98%, and 81-98%, respectively. Based on the available evidence, in 2006-2007, the UK National Institute for Clinical Excellence and the American Cancer Society recommended MRI screening of high-risk women, followed by other international guidelines...
March 27, 2024: Insights Into Imaging
https://read.qxmd.com/read/38536486/technology-and-the-situationist-challenge-to-virtue-ethics
#22
JOURNAL ARTICLE
Fabio Tollon
In this paper, I introduce a "promises and perils" framework for understanding the "soft" impacts of emerging technology, and argue for a eudaimonic conception of well-being. This eudaimonic conception of well-being, however, presupposes that we have something like stable character traits. I therefore defend this view from the "situationist challenge" and show that instead of viewing this challenge as a threat to well-being, we can incorporate it into how we think about living well with technology. Human beings are susceptible to situational influences and are often unaware of the ways that their social and technological environment influence not only their ability to do well, but even their ability to know whether they are doing well...
March 27, 2024: Science and Engineering Ethics
https://read.qxmd.com/read/38536450/surgical-management-of-chiari-ii-malformation-a-systematic-review-of-literature
#23
REVIEW
Rafael C C Vencio, Adriano M Lino-Filho, Renata C F Bonfim, Nayara M Pereira, Cilmária L Franco, Paulo Ronaldo J Ribeiro, Bárbara A Morais
PURPOSE: Chiari II malformation (CM-II) is a congenital malformation of the posterior fossa associated with myelomeningocele. Of the symptomatic patients, 10-33% require surgical treatment. To this date, there is not a consensus about the best surgical technique, and whether to do duroplasty. METHODS: A literature search of the PubMed database and crossed references was performed, per PRISMA guidelines. Data regarding demographic features, extent of cervicomedullary deformity, clinical presentation, surgical techniques, and clinical outcomes were extracted...
March 27, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://read.qxmd.com/read/38536440/circulating-catecholamines-endothelin-1-and-nitric-oxide-releases-do-not-explain-the-preserved-fmd-following-acute-resistance-exercise-in-strength-trained-men
#24
JOURNAL ARTICLE
Takuma Morishima, Nobukazu Kasai
PURPOSE: Acute resistance exercise decreases endothelial function in sedentary individuals but not in strength-trained (ST) individuals. However, the underlying mechanism(s) of vascular protection in ST individuals remains unclear. Herein, we compared catecholamines, endothelin-1 (ET-1), and nitric oxide (NOx) releases after acute resistance exercise between sedentary and ST individuals. METHODS: The untrained (UT) group comprised 12 male individuals with no regular training, while the ST group comprised 12 male individuals...
March 27, 2024: European Journal of Applied Physiology
https://read.qxmd.com/read/38536228/digital-alcohol-interventions-could-be-part-of-the-societal-response-to-harmful-consumption-but-we-know-little-about-their-long-term-costs-and-health-outcomes
#25
JOURNAL ARTICLE
Katarina Ulfsdotter Gunnarsson, Martin Henriksson, Marcus Bendtsen
Alcohol consumption causes both physical and psychological harm and is a leading risk factor for noncommunicable diseases. Digital alcohol interventions have been found to support those looking for help by giving them tools for change. However, whether digital interventions can help tackle the long-term societal consequences of harmful alcohol consumption in a cost-effective manner has not been adequately evaluated. In this Viewpoint, we propose that studies of digital alcohol interventions rarely evaluate the consequences of wider dissemination of the intervention under study, and that when they do, they do not take advantage of modeling techniques that allow for appropriately studying consequences over a longer time horizon than the study period when the intervention is tested...
March 27, 2024: Journal of Medical Internet Research
https://read.qxmd.com/read/38536221/don-t-overlook-syphilis-an-atypical-rash-in-a-woman-with-neurologic-ocular-and-otic-involvement
#26
JOURNAL ARTICLE
Elena M Crouch, Michael T O Stein, Matthew R Geringer, Aeja Weiss, Molly Stalons, Jamie L Geringer
The manifestations of syphilis, a sexually transmitted infection caused by Treponema pallidum, can be divided into primary, secondary, or tertiary stages. In addition, syphilis can cause a latent infection with no clinical manifestations and be diagnosed solely by serologic testing. Secondary syphilis is especially known for causing a rash and diverse clinical manifestation which can make its diagnosis challenging-particularly in patients whose medical and sexual histories do not align with the classical epidemiologic and textbook description of secondary syphilis...
March 25, 2024: Military Medicine
https://read.qxmd.com/read/38536218/views-of-service-users-their-family-or-carers-and-health-care-professionals-on-telerehabilitation-for-people-with-neurological-conditions-in-ghana-qualitative-study
#27
JOURNAL ARTICLE
Lorna Paul, Katie Thomson, Shadrack Osei Asibey, Marian Brady, Frederike van Wijck, Derrick Antwi, Eric Nkansah Opoku, Fred Stephen Sarfo
BACKGROUND: Up to 50% of people in low- and middle-income countries do not receive the rehabilitation they require. Telerehabilitation has the potential to improve access to neurorehabilitation services especially in low- and middle-income countries. Although there are reports of the barriers and facilitators to telerehabilitation in such settings, almost all are anecdotal. Furthermore, family or carers have a significant influence on the adoption and success of telerehabilitation, but their views have not been reported...
March 27, 2024: JMIR MHealth and UHealth
https://read.qxmd.com/read/38536175/physical-activity-and-incident-obesity-across-the-spectrum-of-genetic-risk-for-obesity
#28
JOURNAL ARTICLE
Evan L Brittain, Lide Han, Jeffrey Annis, Hiral Master, Andrew Hughes, Dan M Roden, Paul A Harris, Douglas M Ruderfer
IMPORTANCE: Despite consistent public health recommendations, obesity rates in the US continue to increase. Physical activity recommendations do not account for individual genetic variability, increasing risk of obesity. OBJECTIVE: To use activity, clinical, and genetic data from the All of Us Research Program (AoURP) to explore the association of genetic risk of higher body mass index (BMI) with the level of physical activity needed to reduce incident obesity. DESIGN, SETTING, AND PARTICIPANTS: In this US population-based retrospective cohort study, participants were enrolled in the AoURP between May 1, 2018, and July 1, 2022...
March 4, 2024: JAMA Network Open
https://read.qxmd.com/read/38536152/how-much-do-we-know-about-nursing-care-delivery-models-in-a-hospital-setting-a-mapping-review
#29
REVIEW
Klara Geltmeyer, Kristof Eeckloo, Laurence Dehennin, Emma De Meester, Sigrid De Meyer, Eva Pape, Margot Vanmeenen, Veerle Duprez, Simon Malfait
To deal with the upcoming challenges and complexity of the nursing profession, it is deemed important to reflect on our current organization of care. However, before starting to rethink the organization of nursing care, an overview of important elements concerning nursing care organization, more specifically nursing models, is necessary. The aim of this study was to conduct a mapping review, accompanied by an evidence map to map the existing literature, to map the field of knowledge on a meta-level and to identify current research gaps concerning nursing models in a hospital setting...
March 27, 2024: Nursing Inquiry
https://read.qxmd.com/read/38535979/understanding-multiple-sclerosis-as-a-disease-spectrum-above-and-below-the-clinical-threshold
#30
JOURNAL ARTICLE
Stephen Krieger, Karin Cook, Carrie M Hersh
PURPOSE OF REVIEW: Research in multiple sclerosis (MS) has long been predicated on clinical groupings that do not reflect the underlying biologic heterogeneity apparent within patient populations. This review explicates the various levels of explanation through which the spectrum of disease is described and investigated both above and below the clinical threshold of detection, as framed by the topographical model of MS, to help advance a cogent mechanistic framework. RECENT FINDINGS: Contemporary evidence has amended the view of MS as consisting of sequential disease phases in favor of a spectrum of disease with an admixture of interdependent and dynamic pathobiological axes driving tissue injury and progression...
March 28, 2024: Current Opinion in Neurology
https://read.qxmd.com/read/38535934/firefighters-occupational-exposure-in-preparation-for-wildfire-season-addressing-biological-impact
#31
JOURNAL ARTICLE
Filipa Esteves, Klara Slezakova, Joana Madureira, Josiana Vaz, Adília Fernandes, Simone Morais, Maria do Carmo Pereira, João Paulo Teixeira, Solange Costa
The characterization of wildland firefighters' occupational exposure must consider different exposures, including those at the fire station. The present study aimed to characterize the occupational exposure of 172 Northern Portuguese wildland firefighters in fire stations during the pre-wildfire season of 2021. The biological impact of estimated inhaled doses of PM10 and PM2.5 (indoor/outdoor) was accessed through a buccal micronucleus cytome (BMCyt) assay in exfoliated buccal cells of a subgroup of 80 firefighters...
March 5, 2024: Toxics
https://read.qxmd.com/read/38535889/a-contribution-towards-sustainable-development-in-the-amazon-based-on-a-socioeconomic-and-environmental-analysis-of-visceral-leishmaniasis-in-the-state-of-par%C3%A3-brazil
#32
JOURNAL ARTICLE
Claudia do Socorro Carvalho Miranda, Bruna Costa de Souza, Eric Renato Lima Figueiredo, João Simão de Melo Neto, Hilton Pereira da Silva, Marcos Valerio Santos da Silva, Sérgio Luiz Althoff, Tainara Carvalho Garcia Miranda Filgueiras, Debora do Socorro Carvalho Miranda, Nelson Veiga Gonçalves
Human Visceral Leishmaniasis is an endemic public health problem in the Amazon. This article analyzed the spatial distribution of this disease and its relationship with socioeconomic, environmental and public health policy variables in four mesoregions of the state of Pará, from 2011 to 2022. This ecological study used secondary data obtained from official Brazilian agencies. Spatial analysis was performed using the Flow, Kernel and Global Moran bivariate techniques expressed in thematic maps. In the mesoregions studied, 2685 cases of the disease were confirmed, with the highest number of cases in Southeast Pará state...
March 21, 2024: Tropical Medicine and Infectious Disease
https://read.qxmd.com/read/38535877/integrated-strategies-for-aedes-aegypti-control-applied-to-individual-houses-an-approach-to-mitigate-vectorial-arbovirus-transmission
#33
JOURNAL ARTICLE
Danielle Cristina Tenório Varjal de Melo, Eloína Maria de Mendonça Santos, Morgana Nascimento Xavier, Josimara do Nascimento, Victor Araújo Barbosa, André Luiz de Sá Oliveira, Marcos Vinícius Meiado, Maria Alice Varjal de Melo-Santos, Marcelo Henrique Santos Paiva, Gabriel da Luz Wallau, Cláudia Maria Fontes de Oliveira
Aedes aegypti and Culex quinquefasciatus mosquitoes are vectors of different arboviruses that cause a large burden of disease in humans worldwide. A key step towards reducing the impact of arboviruses on humans can be achieved through integrated mosquito surveillance and control approaches. We carried out an integrated approach of mosquito surveillance and control actions to reduce populations of these insects along with a viral surveillance in a neighborhood of Recife (Northeastern Brazil) with high mosquito densities and arbovirus transmission...
February 24, 2024: Tropical Medicine and Infectious Disease
https://read.qxmd.com/read/38535874/association-between-prepregnancy-body-mass-index-and-newborn-breastfeeding-initiation
#34
JOURNAL ARTICLE
Melanie Boyd, Clare C Brown, Anthony Goudie
Background: The benefits of breastfeeding a newborn are well documented. Identification of mothers who do not initiate breastfeeding is essential for developing initiatives to improve breastfeeding initiation. Methods: The study used data from the National Center for Health Statistics (NCHS) National Vital Statistics System (NVSS) birth certificate data (2014-2021) to identifying 15,599,930 in-hospital deliveries. We used multivariable logistic regression to assess the association between seven body mass index (BMI) categories and initiation of breastfeeding before hospital discharge...
March 27, 2024: Breastfeeding Medicine
https://read.qxmd.com/read/38535809/new-insights-into-interactions-between-mushroom-aegerolysins-and-membrane-lipids
#35
JOURNAL ARTICLE
Larisa Lara Popošek, Nada Kraševec, Gregor Bajc, Urška Glavač, Matija Hrovatin, Žan Perko, Ana Slavič, Miha Pavšič, Kristina Sepčić, Matej Skočaj
Aegerolysins are a family of proteins that recognize and bind to specific membrane lipids or lipid domains; hence they can be used as membrane lipid sensors. Although aegerolysins are distributed throughout the tree of life, the most studied are those produced by the fungal genus Pleurotus . Most of the aegerolysin-producing mushrooms code also for proteins containing the membrane attack complex/perforin (MACPF)-domain. The combinations of lipid-sensing aegerolysins and MACPF protein partners are lytic for cells harboring the aegerolysin membrane lipid receptor and can be used as ecologically friendly bioinsecticides...
March 9, 2024: Toxins
https://read.qxmd.com/read/38535808/potential-biotechnological-applications-of-venoms-from-the-viperidae-family-in-central-america-for-thrombosis
#36
REVIEW
Jorge Eduardo Chang Estrada, Taissa Nunes Guerrero, Daniel Fernando Reyes-Enríquez, Erica Santos Nardy, Roseane Guimarães Ferreira, Cristian José Ruiz Calderón, Irmgardt A Wellmann, Kaio Murilo Monteiro Espíndola, Alejandro Ferraz do Prado, Andreimar Martins Soares, Marcos Roberto de Mattos Fontes, Marta Chagas Monteiro, Russolina Benedeta Zingali
Central America is home to one of the most abundant herpetofauna in the Americas, occupying only 7% of the continent's total area. Vipers and lizards are among the most relevant venomous animals in medical practice due to the consequences of envenomation from the bite of these animals. A great diversity of biomolecules with immense therapeutic and biotechnological value is contained in their venom. This paper describes the prominent leading representatives of the family Viperidae , emphasizing their morphology, distribution, habitat, feeding, and venom composition, as well as the biotechnological application of some isolated components from the venom of the animals from these families, focusing on molecules with potential anti-thrombotic action...
March 8, 2024: Toxins
https://read.qxmd.com/read/38535789/real-life-treatment-outcome-of-botulinum-toxin-a-injection-on-overactive-bladder-and-voiding-dysfunction-in-patients-with-central-nervous-system-lesions
#37
JOURNAL ARTICLE
Yuan-Hong Jiang, Jia-Fong Jhang, Sheng-Fu Chen, Hann-Chorng Kuo
PURPOSE: Neurogenic lower urinary tract dysfunction (NLUTD) is common in patients with neurological lesions in the central nervous system (CNS). Medical treatment usually cannot adequately relieve NLUTD. This study reported the real-life treatment outcome of botulinum toxin A (BoNT-A) for overactive bladders (OAB) and voiding dysfunction in patients with CNS lesions. METHODS: We retrospectively analyzed the first-time treatment outcome of 74 patients who received detrusor 100 U BoNT-A for OAB and 45 patients who received a urethral sphincter 100 U BoNT-A injection for voiding dysfunction...
March 1, 2024: Toxins
https://read.qxmd.com/read/38535786/bee-venom-composition-and-anticancer-properties
#38
REVIEW
Goran Gajski, Elina Leonova, Nikolajs Sjakste
Among the various natural compounds used in alternative and Oriental medicine, toxins isolated from different organisms have had their application for many years, and Apis mellifera venom has been studied the most extensively. Numerous studies dealing with the positive assets of bee venom (BV) indicated its beneficial properties. The usage of bee products to prevent the occurrence of diseases and for their treatment is often referred to as apitherapy and is based mainly on the experience of the traditional system of medical practice in diverse ethnic communities...
February 29, 2024: Toxins
https://read.qxmd.com/read/38535651/energy-storage-performance-of-electrode-materials-derived-from-manganese-metal-organic-frameworks
#39
JOURNAL ARTICLE
Gyeongbeom Ryoo, Seon Kyung Kim, Do Kyung Lee, Young-Jin Kim, Yoon Soo Han, Kyung-Hye Jung
Metal-organic frameworks (MOFs) are porous materials assembled using metal and organic linkers, showing a high specific surface area and a tunable pore size. Large portions of metal open sites in MOFs can be exposed to electrolyte ions, meaning they have high potential to be used as electrode materials in energy storage devices such as supercapacitors. Also, they can be easily converted into porous metal oxides by heat treatment. In this study, we obtained high energy storage performance by preparing electrode materials through applying heat treatment to manganese MOFs (Mn-MOFs) under air...
March 11, 2024: Nanomaterials
https://read.qxmd.com/read/38535406/thrips-species-composition-in-ontario-greenhouse-floriculture-innovative-identification-tools-and-implications-for-integrated-pest-management
#40
JOURNAL ARTICLE
Sarah Elizabeth Jandricic, Ashley Summerfield, H Eric L Maw, Bryan M T Brunet, Rosemarije Buitenhuis
Proper species identification is the keystone of successful integrated pest management (IPM). However, efforts to identify thrips species in Canadian greenhouses have not been formally made since the 1980s. In response to recent increases in crop damage, we sampled thrips communities from eight commercial floriculture greenhouses in the Niagara region (Ontario, Canada) from May until August 2016. Selected sites were revisited in 2017, 2018, and 2019 to determine changes in species composition over time. Western flower thrips ( Frankliniella occidentalis (Pergande)), along with onion thrips ( Thrips tabaci Lindeman), constituted the majority of species found...
March 21, 2024: Insects
keyword
keyword
39577
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.