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https://www.readbyqxmd.com/read/29684944/comparing-categorical-and-probabilistic-fingerprint-evidence
#1
Brandon Garrett, Gregory Mitchell, Nicholas Scurich
Fingerprint examiners traditionally express conclusions in categorical terms, opining that impressions do or do not originate from the same source. Recently, probabilistic conclusions have been proposed, with examiners estimating the probability of a match between recovered and known prints. This study presented a nationally representative sample of jury-eligible adults with a hypothetical robbery case in which an examiner opined on the likelihood that a defendant's fingerprints matched latent fingerprints in categorical or probabilistic terms...
April 23, 2018: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29684885/abnormal-muscle-activation-patterns-are-associated-with-chronic-gait-deficits-following-traumatic-brain-injury
#2
Samuel A Acuña, Mitchell E Tyler, Yuri P Danilov, Darryl G Thelen
BACKGROUND: Gait and balance disorders are common among individuals who have experienced a mild to moderate traumatic brain injury (TBI). However, little is known about how the neuromuscular control of gait is altered following a TBI. RESEARCH QUESTION: Investigate the relationship between lower limb muscle activation patterns and chronic gait deficits in individuals who previously experienced a mild to moderate TBI. METHODS: Lower extremity electromyographic (EMG) signals were collected bilaterally during treadmill and overground walking in 44 ambulatory individuals with a TBI >1 year prior and 20 unimpaired controls...
April 12, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29684874/treatment-of-an-azo-dye-effluent-by-peroxi-coagulation-and-its-comparison-to-traditional-electrochemical-advanced-processes
#3
Edilson do Vale-Júnior, Djalma R da Silva, Ana S Fajardo, Carlos A Martínez-Huitle
Peroxi-coagulation (PC) is an interesting new process that has not been widely studied in the literature. This work presents the application of this technology to treat an azo dye synthetic effluent, studying the effect of different parameters including initial pH, current density (j), initial dye concentration and supporting electrolyte. The two former variables significantly affected the colour removal of the wastewater, followed by the initial dye concentration and the kind of electrolyte, in a lesser extent...
April 5, 2018: Chemosphere
https://www.readbyqxmd.com/read/29684838/-doing-it-for-real-now-the-transition-from-healthcare-assistant-to-newly-qualified-nurse-a-qualitative-study
#4
Jan Draper
BACKGROUND: There has been increasing international research and policy interest concerning the transition from student to newly qualified nurse (NQN). However, the influence of previous employment as a healthcare assistant (HCA) on students' experiences of this transition is comparatively under-researched. AIMS AND OBJECTIVES: To explore the experiences of NQNs also employed as HCAs during their pre-registration education programme and how this prior and ongoing HCA experience influenced their transition experiences...
April 16, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29684826/ongoing-child-welfare-services-understanding-the-relationship-of-worker-and-organizational-characteristics-to-service-provision
#5
Kristen Lwin, John Fluke, Nico Trocmé, Barbara Fallon, Faye Mishna
Ongoing child welfare services are put in place after completion of the initial maltreatment investigation when there is a perceived need to mitigate the risk of future harm. The knowledge of how clinical, worker, and organizational characteristics interact with this decision to provide ongoing child welfare services is not well integrated in the research literature. Using secondary data from the Canadian Incidence Study of Reported Child Abuse and Neglect-2008, this study's primary objective is to understand the relationship of clinical, worker, and organizational characteristics to the decision to transfer a case to ongoing child welfare services and their relative contribution to the transfer decision in Canada...
April 20, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29684796/-they-told-me-all-mothers-have-worries-stillborn-mother-s-experiences-of-having-a-gut-instinct-that-something-is-wrong-in-pregnancy-findings-from-an-international-case-control-study
#6
Jane Warland, Alexander E P Heazell, Tomasina Stacey, Christin Coomarasamy, Jayne Budd, Edwin A Mitchell, Louise M O'Brien
OBJECTIVE: To describe and explore 'gut instinct' that something was wrong in women who identified that they experienced gut instinct during pregnancy. METHOD: A case-control study utilising an international web-based questionnaire. Stillborn cases (n = 146) and liveborn controls (n = 234) answered the gut instinct question within 30 days of the pregnancy ending. Of those, 84 cases and 27 controls also provided qualitative comment data. Descriptive statistics were used for the question, with a fixed option and summative content analysis was used to analyse the comment data...
April 11, 2018: Midwifery
https://www.readbyqxmd.com/read/29684783/accurate-segmenting-of-cervical-tumors-in-pet-imaging-based-on-similarity-between-adjacent-slices
#7
Liyuan Chen, Chenyang Shen, Zhiguo Zhou, Genevieve Maquilan, Kimberly Thomas, Michael R Folkert, Kevin Albuquerque, Jing Wang
Because in PET imaging cervical tumors are close to the bladder with high capacity for the secreted 18 FDG tracer, conventional intensity-based segmentation methods often misclassify the bladder as a tumor. Based on the observation that tumor position and area do not change dramatically from slice to slice, we propose a two-stage scheme that facilitates segmentation. In the first stage, we used a graph-cut based algorithm to obtain initial contouring of the tumor based on local similarity information between voxels; this was achieved through manual contouring of the cervical tumor on one slice...
April 16, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29684777/random-spectrum-fatigue-performance-of-severely-plastically-deformed-titanium-for-implant-dentistry-applications
#8
D Rittel, K Shemtov-Yona, R Lapovok
Severe plastic deformation (SPD) has long been known to confer superior mechanical properties for many metals and alloys. In the general field of biomedical devices, and dental implants in particular, the superior strength of SPD-processed commercially pure (CP) titanium, that may surpass that of the stronger Ti6Al4V alloy, has been associated with a superior fatigue resistance. Such a property would make those materials both biocompatible and strong alternatives to the currently used titanium alloy. However, the fatigue characterization reported so far in the literature relies on a very small sample size, thereby precluding any meaningful statistical analysis...
April 14, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29684673/exercise-as-a-therapeutic-intervention-to-optimize-fetal-weight
#9
REVIEW
Laura M Reyes, Margie H Davenport
The Developmental Origins of Health and Disease suggest the in utero environment programs offspring obesity and cardiovascular disease. Therefore, there is a need to implement safe therapeutic interventions that do not involve the intake of medications or biological products during pregnancy that can improve maternal and fetal health. Prenatal exercise is established to promote maternal and fetal health. It is generally recommended that women accumulate at least 150 minutes per week of moderate-intensity exercise...
April 20, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29684646/granger-geweke-causality-estimation-and-interpretation
#10
Mukesh Dhamala, Hualou Liang, Steven L Bressler, Mingzhou Ding
In a recent PNAS article1 , Stokes and Purdon performed numerical simulations to argue that Granger-Geweke causality (GGC) estimation is severely biased, or of high variance, and GGC application to neuroscience is problematic because the GGC measure is independent of 'receiver' dynamics. Here, we use the same simulation examples to show that GGC measures, when properly estimated either via the spectral factorization-enabled nonparametric approach or the VAR-model based parametric approach, do not have the claimed bias and high variance problems...
April 20, 2018: NeuroImage
https://www.readbyqxmd.com/read/29684601/the-effect-of-intermittent-hypoxia-under-different-temperature-on-the-immunomodulation-in-streptococcus-agalactiae-vaccinated-nile-tilapia-oreochromis-niloticus
#11
Jing Wang, Dan-Qi Lu, Biao Jiang, Heng-Li Luo, Ge-Ling Lu, An-Xing Li
Dissolved oxygen (DO) and temperature are the potential immunomodulators in fish and play the important roles in regulating immunity. We studied the effect of intermittent hypoxia under different temperature on the immunomodulation in vaccinated Nile tilapia (Oreochromis niloticus). The expression of immune-related genes, enzymatic activities, histology, cumulative mortality, and S. agalactiae clearance were assessed. Study conditions were intermittently hypoxic (4.0 ± 1.0 mg/L DO) at 30 ± 0.5 °C or 35 ± 0...
April 20, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29684568/current-trends-in-food-allergy-induced-anaphylaxis-management-at-school
#12
REVIEW
Matthew Greenhawt, Dana Wallace, Wesley Sublet, Erin Maughan, Andrea Tanner, Kevin Kelly, Stanley Fineman, Martha White, Gene Cash, Charmayne Anderson, Sally Schoessler, Ruchi Gupta, Michael Pistiner
OBJECTIVE: To review the evidence and current policies regarding the use of epinephrine at schools and child care centers Data Sources and Study Selection: A narrative review was performed based on the result of conference proceedings of a group of inter-professional stakeholders who attended the USAnaphylaxis Summit 2017 presented by Allergy & Asthma Network. RESULTS: Anaphylaxis is a well-recognized medical emergency requiring prompt treatment with intramuscular epinephrine...
April 20, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29684553/fission-yeast-cells-overproducing-hset-kifc1-provides-a-useful-tool-for-identification-and-evaluation-of-human-kinesin-14-inhibitors
#13
Masashi Yukawa, Tomoaki Yamauchi, Naoaki Kurisawa, Shakil Ahmed, Ken-Ichi Kimura, Takashi Toda
Many human cancer cells contain more than two centrosomes, yet these cancer cells can form pseudo-bipolar spindles through the mechanism, called centrosome clustering, and survive, instead of committing lethal multipolar mitoses. Kinesin-14/HSET, a minus end-directed motor, plays a crucial role in centrosome clustering. Accordingly, HSET is deemed to be a promising chemotherapeutic target to selectively kill cancer cells. Recently, three HSET inhibitors (AZ82, CW069 and SR31527) have been reported, but their specificity and efficacy have not been evaluated rigorously...
April 20, 2018: Fungal Genetics and Biology: FG & B
https://www.readbyqxmd.com/read/29684494/quality-assessment-and-artificial-neural-networks-modeling-for-characterization-of-chemical-and-physical-parameters-of-potable-water
#14
Marjan Salari, Esmail Salami, Seyed Hossein Afzali, Majid Ehteshami, Gea Oliveri Conti, Zahra Derakhshan, Solmaz Nikbakht Sheibani
Today, due to the increase in the population, the growth of industry and the variety of chemical compounds, the quality of drinking water has decreased. Five important river water quality properties such as: dissolved oxygen (DO), total dissolved solids (TDS), total hardness (TH), alkalinity (ALK) and turbidity (TU) were estimated by parameters such as: electric conductivity (EC), temperature (T), and pH that could be measured easily with almost no costs. Simulate water quality parameters were examined with two methods of modeling include mathematical and Artificial Neural Networks (ANN)...
April 20, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29684479/impairment-of-the-gn%C3%AE-11-controlled-expression-of-claudin-1-and-mmp-9-and-collective-migration-of-human-breast-cancer-mcf-7-cells-by-dheas
#15
Neha Upmanyu, Ahmed Bulldan, Dimitrios Papadopoulos, Raimund Dietze, Viveka Nand Malviya, Georgios Scheiner-Bobis
Although dehydroepiandrosterone sulfate (DHEAS) constitutes the most abundant steroid in humans, in-depth investigations of its effects are rather scarce. We address here DHEAS effects on the estrogen receptor-positive metastatic human breast cancer cell line MCF-7. We focus on DHEAS-mediated signaling that might influence expression of claudin-1 and matrix metalloproteinase-9 (MMP-9), both known to be critical factors for migration and invasiveness of various cancers, including breast cancer cells. Physiological concentrations of DHEAS trigger persistent phosphorylation of Erk1/2 in MCF-7 cells...
April 20, 2018: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29684474/environmental-enrichment-cognitive-neuroprotection-in-an-experimental-model-of-cerebral-ischemia-biochemical-and-molecular-aspects
#16
Lara Vezula Gonçalves, Alice Laschuk Herlinger, Tamara Andrea Alarcon Ferreira, Juliana Barbosa Coitinho, Rita Gomes Wanderley Pires, Cristina Martins-Silva
Stroke is considered a major cause of global morbidity. Currently, there are no effective treatments for post-stroke cognitive impairment. Enriched environment (EE) has been brought forward as a preconditioning method to induce cerebral tolerance in an ischemic event. However, the subjacent mechanisms involved in this tolerance are not yet clear. Herein we aimed to identify the mechanisms of neuroprotection triggered by EE preconditioning in a murine model of ischemic stroke. In order to do so, C57Bl/6 mice were kept for five weeks either in EE or in standard environment (SC) prior to ischemic injury through bilateral carotid occlusion (BCCAo) or sham surgery...
April 20, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29684431/an-adverse-outcome-pathway-aop-for-forestomach-tumors-induced-by-non-genotoxic-initiating-events
#17
Deborah M Proctor, Mina Suh, Grace Chappell, Susan J Borghoff, Chad M Thompson, Karin Wiench, Lavorgie Finch, Robert Ellis-Hutchings
The utility of rodent forestomach tumor data for hazard and risk assessment has been examined for decades because humans do not have a forestomach, and these tumors occur by varying modes of action (MOAs). We have used the MOA for ethyl acrylate (EA) to develop an Adverse Outcome Pathway (AOP) for forestomach tumors caused by non-genotoxic initiating events. These tumors occur secondary to site of contact induced epithelial cytotoxicity and regenerative repair-driven proliferation. For EA, the critical initiating event (IE) is epithelial cytotoxicity, and supporting key events (KEs) at the cellular and tissue level are increased cell proliferation (KE1) resulting in sustained hyperplasia (KE2), with the adverse outcome of forestomach papillomas and carcinomas...
April 20, 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29684400/no-evidence-for-sex-specific-effects-of-the-maternal-social-environment-on-offspring-development-in-japanese-quail-coturnix-japonica
#18
Esther Ma Langen, Nikolaus von Engelhardt, Vivian C Goerlich-Jansson
The social environment of reproducing females can cause physiological changes, with consequences for reproductive investment and offspring development. These prenatal maternal effects are often found to be sex-specific and may have evolved as adaptations, maximizing fitness of male and female offspring for their future environment. Female hormone levels during reproduction are considered a potential mechanism regulating sex allocation in vertebrates: high maternal androgens have repeatedly been linked to increased investment in sons, whereas high glucocorticoid levels are usually related to increased investment in daughters...
April 20, 2018: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/29684348/crystal-structure-of-a-thermophilic-o-6-alkylguanine-dna-alkyltransferase-derived-self-labeling-protein-tag-in-covalent-complex-with-a-fluorescent-probe
#19
Franca Rossi, Castrese Morrone, Alberto Massarotti, Davide Maria Ferraris, Anna Valenti, Giuseppe Perugino, Riccardo Miggiano
The self-labeling protein tags are robust and versatile tools for studying different molecular aspects of cell biology. In order to be suitable for a wide spectrum of experimental conditions, it is mandatory that these systems are stable after the fluorescent labeling reaction and do not alter the properties of the fusion partner. SsOGT-H5 is an engineered variant alkylguanine-DNA-alkyl-transferase (OGT) of the hyperthermophilic archaeon Sulfolobus solfataricus, and it represents an alternative solution to the SNAP-tag® technology under harsh reaction conditions...
April 20, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29684327/do-health-promotion-messages-integrate-unintended-pregnancy-and-sti-prevention-a-content-analysis-of-online-information-for-adolescents-and-young-adults
#20
Riley J Steiner, Catherine N Rasberry, Jessica M Sales, Laura M Gaydos, Karen Pazol, Michael Kramer, Andrea Swartzendruber
OBJECTIVE: Recently there have been calls to strengthen integration of unintended pregnancy and sexually transmitted infection (STI) prevention messages, spurred by increasing use of long-acting reversible contraception. To assess the extent to which public health/clinical messages about unintended pregnancy prevention also address STI prevention, we conducted a content analysis of web-based health promotion information for young people. STUDY DESIGN: Websites identified through a systematic Google search were eligible for inclusion if they were operated by a United States-based organization with a mission related to public health/clinical services and the URL included: 1) original content; 2) about sexual and reproductive health; 3) explicitly for adolescents and/or young adults...
April 20, 2018: Contraception
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