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https://www.readbyqxmd.com/read/28239923/we-know-that-horses-sweat-and-men-perspire-but-do-ladies-merely-glow
#1
Daniel Gagnon
For some time, the euphemism "horses sweat, men perspire, but ladies merely glow" was scientifically supported. Initial studies examining gender differen0063es in sweat production generally observed that women sweat less than men during heat exposure (i.e. they merely glow). This article is protected by copyright. All rights reserved.
February 26, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28239918/what-is-a-nurse-the-francis-report-and-the-historic-voice-of-nursing
#2
Ann Bradshaw
Following the Francis report into shockingly deficient standards of care at an English hospital, this paper examines UK nurse education and revisits the premises on which the professional narrative of nursing was built. The UK government's response to the report is to introduce the "associate nurse" role, to be nationally trained to do fundamental care in place of the registered nurse, and a nursing apprenticeship scheme-on-the-job training for a nursing degree. UK nursing bodies do not address the report's recommendations in regard to registered nurse education; rather, they advocate a further perpetuation of the current system...
February 26, 2017: Nursing Inquiry
https://www.readbyqxmd.com/read/28239876/the-potential-of-volatile-organic-compounds-for-the-detection-of-active-disease-in-patients-with-ulcerative-colitis
#3
A Smolinska, A G L Bodelier, J W Dallinga, A A M Masclee, D M Jonkers, F-J van Schooten, M J Pierik
BACKGROUND: To optimise treatment of ulcerative colitis (UC), patients need repeated assessment of mucosal inflammation. Current non-invasive biomarkers and clinical activity indices do not accurately reflect disease activity in all patients and cannot discriminate UC from non-UC colitis. Volatile organic compounds (VOCs) in exhaled air could be predictive of active disease or remission in Crohn's disease. AIM: To investigate whether VOCs are able to differentiate between active UC, UC in remission and non-UC colitis...
February 26, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28239778/-minimally-invasive-bypass-surgery-for-nasolacrimal-duct-obstruction-transcanalicular-laser-assisted-dacryocystorhinostomy
#4
K R Koch, C Cursiefen, L M Heindl
BACKGROUND: In recent years, the minimally invasive surgical procedure of transcanalicular laser-assisted dacryocystorhinostomy (TKL-DCR) has gained importance in the treatment of primary acquired nasolacrimal duct obstructions (PANDO). OBJECTIVES: Surgical indications, functional success rates, potential advantages, and complications of TKL-DCR are presented and compared with the standard procedures external (EXT-DCR) and endonasal DCR (EN-DCR). METHODS: The study comprises a PubMed literature review and our own clinical results...
February 26, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28239771/can-training-change-attentional-breadth-failure-to-find-transfer-effects
#5
Lin Fang, Kristof Hoorelbeke, Lynn Bruyneel, Lies Notebaert, Colin MacLeod, Rudi De Raedt, Ernst H W Koster
Recently, there is increasing interest in the causal relationship between attentional breadth and emotion regulation. To test this causal relationship, attentional breadth needs to be manipulated stringently. The aim of the current research was to establish whether visual attentional breadth could be manipulated through experimental training procedures. We conducted two single-session training experiments and one multiple-session training experiment, all of which contained pre- and post-training assessments to test the direct transfer effects of training on attentional breadth construed in different measures...
February 26, 2017: Psychological Research
https://www.readbyqxmd.com/read/28239758/acellular-mouse-kidney-ecm-can-be-used-as-a-three-dimensional-substrate-to-test-the-differentiation-potential-of-embryonic-stem-cell-derived-renal-progenitors
#6
Manpreet Sambi, Theresa Chow, Jennifer Whiteley, Mira Li, Shawn Chua, Vanessa Raileanu, Ian M Rogers
The development of strategies for tissue regeneration and bio-artificial organ development is based on our understanding of embryogenesis. Differentiation protocols attempt to recapitulate the signaling modalities of gastrulation and organogenesis, coupled with cell selection regimens to isolate the cells of choice. This strategy is impeded by the lack of optimal in vitro culture systems since traditional culture systems do not allow for the three-dimensional interaction between cells and the extracellular matrix...
February 27, 2017: Stem Cell Reviews
https://www.readbyqxmd.com/read/28239746/induction-of-sa-signaling-pathway-and-ethylene-biosynthesis-in-trichoderma-harzianum-treated-tomato-plants-after-infection-of-the-root-knot-nematode-meloidogyne-incognita
#7
Paola Leonetti, Maria Chiara Zonno, Sergio Molinari, Claudio Altomare
Salicylic acid-signaling pathway and ethylene biosynthesis were induced in tomato treated with Trichoderma harzianum when infected by root-knot nematodes and limited the infection by activation of SAR and ethylene production. Soil pre-treatment with Trichoderma harzianum (Th) strains ITEM 908 (T908) and T908-5 decreased susceptibility of tomato to Meloidogyne incognita, as assessed by restriction in nematode reproduction and development. The effect of T. harzianum treatments on plant defense was detected by monitoring the expression of the genes PR-1/PR-5 and JERF3/ACO, markers of the SA- and JA/ET-dependent signaling pathways, respectively...
February 26, 2017: Plant Cell Reports
https://www.readbyqxmd.com/read/28239699/stabilization-of-carbocations-ch3-c2h5-i-c3h7-tert-bu-and-cyclo-pentyl-in-solid-phases-experimental-data-versus-calculations
#8
Evgenii S Stoyanov, Anton S Nizovtsev
Comparison of experimental infrared (IR) spectra of the simplest carbocations (with the weakest carborane counterions in terms of basicity, CHB11Hal11(-), Hal = F, Cl) with their calculated IR spectra revealed that they are completely inconsistent, as previously reported for the t-Bu(+) cation [Stoyanov E. S., et al. J. Phys. Chem. A, 2015, 119, 8619]. This means that the generally accepted explanation of hyperconjugative stabilization of the carbocations should be revised. According to the theory, one CH bond (denoted as ) from each CH3/CH2 group transfers its σ-electron density to the empty 2pz orbital of the sp(2) C atom, whereas the σ-electron density on the other CH bonds of the CH3/CH2 group slightly increases...
February 27, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28239671/development-of-a-model-to-determine-mass-transfer-coefficient-and-oxygen-solubility-in-bioreactors
#9
Johnny Lee
The objective of this paper is to present an experimentally validated mechanistic model to predict the oxygen transfer rate coefficient (Kla) in aeration tanks for different water temperatures. Using experimental data created by Hunter and Vogelaar, the formula precisely reproduces experimental results for the standardized Kla at 20 °C, comparatively better than the current model used by ASCE 2-06 based on the equation Kla20 = Kla. ([Formula: see text])((20-T)) where T is in °C. Currently, reported values for [Formula: see text] range from 1...
February 2017: Heliyon
https://www.readbyqxmd.com/read/28239666/making-the-most-of-rna-seq-pre-processing-sequencing-data-with-opossum-for-reliable-snp-variant-detection
#10
Laura Oikkonen, Stefano Lise
Identifying variants from RNA-seq (transcriptome sequencing) data is a cost-effective and versatile alternative to whole-genome sequencing. However, current variant callers do not generally behave well with RNA-seq data due to reads encompassing intronic regions. We have developed a software programme called Opossum to address this problem. Opossum pre-processes RNA-seq reads prior to variant calling, and although it has been designed to work specifically with Platypus, it can be used equally well with other variant callers such as GATK HaplotypeCaller...
January 17, 2017: Wellcome Open Res
https://www.readbyqxmd.com/read/28239603/framing-undergraduate-public-health-education-as-liberal-education-who-are-we-training-our-students-to-be-and-how-do-we-do-that
#11
Marc T Kiviniemi, Sara L C Mackenzie
The rapid development of the undergraduate major in public health over the past 15 years has led to a debate about the most appropriate framing for the degree. Should it be viewed as a liberal education degree (akin to academic disciplines such as psychology and political science) or as a professional training degree (akin to disciplines such as nursing and management)? This paper presents an overview of both the liberal education and the professional training degree approaches to the undergraduate public health degree...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28239597/perceived-cognitive-deficits-are-associated-with-diabetes-self-management-in-a-multiethnic-sample
#12
Heather Cuevas, Alexa Stuifbergen
BACKGROUND: People with diabetes have almost twice the risk of developing cognitive impairment or dementia as do those without diabetes, and about half of older adults with diabetes will become functionally disabled or cognitively impaired. But diabetes requires complex self-management: patients must learn about the implications of their disease; manage their diets, physical activity, and medication; and monitor their blood glucose. Difficulties with cognition can hinder these activities...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/28239574/do-nasal-surgeries-affect-mucociliary-clearance
#13
Rajeshwary Aroor, Zainab Sunu Ali, K S Gangadhara Somayaji
The study was conducted to assess the impact of different nasal surgeries on the nasal mucociliary clearance mechanism. Mucociliary function of the nasal mucosa of patients who were undergoing various nasal surgeries was assessed by the Saccharin test by placing 5 mg saccharin granule on the anterior end of the inferior turbinate 1 day prior to the surgery. The time required for the test subject to experience a sweet taste was measured in minutes. Post-operatively the test was repeated 6 weeks after the surgery and the test times were compared...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239502/immunooncology-can-the-right-chimeric-antigen-receptors-t-cell-design-be-made-to-cure-all-types-of-cancers-and-will-it-be-covered
#14
REVIEW
Regina Au
Immunooncology (IO) is the buzz word today and it has everyone doing IO research. If we look back at the history of cancer treatment, the survival rate was measured in months which, according to oncologists, was a lot back then because the mortality rate in most cancers was 100%. However, most traditional chemotherapies were not well tolerated because they would kill both cancerous and healthy cells, which lead to major side effects such as loss of hair, nausea and vomiting, and risk of infection. Survival was better but not much better depending on the type of cancer and the patient's own genetic and physiological make-up...
2017: Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28239457/covariate-selection-for-multilevel-models-with-missing-data
#15
Miguel Marino, Orfeu M Buxton, Yi Li
Missing covariate data hampers variable selection in multilevel regression settings. Current variable selection techniques for multiply-imputed data commonly address missingness in the predictors through list-wise deletion and stepwise-selection methods which are problematic. Moreover, most variable selection methods are developed for independent linear regression models and do not accommodate multilevel mixed effects regression models with incomplete covariate data. We develop a novel methodology that is able to perform covariate selection across multiply-imputed data for multilevel random effects models when missing data is present...
2017: Stat: the ISI's Journal for Rapid Dissemination of Statistics Research
https://www.readbyqxmd.com/read/28239433/domain-adaptation-with-conditional-transferable-components
#16
Mingming Gong, Kun Zhang, Tongliang Liu, Dacheng Tao, Clark Glymour, Bernhard Schölkopf
Domain adaptation arises in supervised learning when the training (source domain) and test (target domain) data have different distributions. Let X and Y denote the features and target, respectively, previous work on domain adaptation mainly considers the covariate shift situation where the distribution of the features P(X) changes across domains while the conditional distribution P(Y∣X) stays the same. To reduce domain discrepancy, recent methods try to find invariant components [Formula: see text] that have similar [Formula: see text] on different domains by explicitly minimizing a distribution discrepancy measure...
June 2016: JMLR Workshop and Conference Proceedings
https://www.readbyqxmd.com/read/28239430/hiv-infected-children-in-the-asia-pacific-region-with-baseline-severe-anemia-antiretroviral-therapy-and-outcomes
#17
Pagakrong Lumbiganon, Pope Kosalaraksa, Torsak Bunupuradah, David Boettiger, Vonthanak Saphonn, Khanh H Truong, Nia Kurniati, Rawiwan Hansudewechakul, Viet C Do, Tavitiya Sudjaritruk, Nagalingeswaran Kumarasamy, Nantakar Kongstan, Nik K N Yusoff, Lam V Nguyen, Dewi K Wati, Kamarul Razali, Annette H Sohn, Azar Kariminia
BACKGROUND: Severe anemia is common among children infected with human immunodeficiency virus (HIV). The choice of antiretroviral (ART) regimen needs careful consideration. No information is available regarding the initial ART regimens used in the Asia-Pacific region and the rate of switch of ART regimens in HIV-infected children with severe anemia. OBJECTIVES: To study the initial ART regimens and the rate of switch of ART regimens used during the first 36 months in HIV-infected children with severe anemia and to evaluate their clinical and laboratory outcomes...
June 2016: Asian Biomedicine: Research, Reviews and News
https://www.readbyqxmd.com/read/28239418/-classical-cytogenetics-is-not-equal-to-banding-cytogenetics
#18
Thomas Liehr
BACKGROUND: Human cytogenetics is a field suffering from the argumentation that it 'is nowadays really outdated and to be replaced by molecular high throughput approaches'. Thus, it is to be expected that non-cytogeneticists do mistakes in nomenclature of cytogenetics, which is exposed to repeated reforms, like e.g. recently the now hardly manageable and readable nomenclature for array-comparative genomic hybridization. RESULTS: An unexpected nomenclature problem becomes more and more obvious in human cytogenetics - it seems to become difficult to understand how and when to use the designations "classical cytogenetics" or "banding cytogenetics"...
2017: Molecular Cytogenetics
https://www.readbyqxmd.com/read/28239401/group-or-ungroup-moose-behavioural-response-to-recolonization-of-wolves
#19
Johan Månsson, Marie-Caroline Prima, Kerry L Nicholson, Camilla Wikenros, Håkan Sand
BACKGROUND: Predation risk is a primary motivator for prey to congregate in larger groups. A large group can be beneficial to detect predators, share predation risk among individuals and cause confusion for an attacking predator. However, forming large groups also has disadvantages like higher detection and attack rates of predators or interspecific competition. With the current recolonization of wolves (Canis lupus) in Scandinavia, we studied whether moose (Alces alces) respond by changing grouping behaviour as an anti-predatory strategy and that this change should be related to the duration of wolf presence within the local moose population...
2017: Frontiers in Zoology
https://www.readbyqxmd.com/read/28239356/sex-and-exercise-intensity-do-not-influence-oxygen-uptake-kinetics-in-submaximal-swimming
#20
Joana F Reis, Gregoire P Millet, Paula M Bruno, Veronica Vleck, Francisco B Alves
The aim of this study was to compare the oxygen uptake ([Formula: see text]) kinetics in front crawl between male and female swimmers at moderate and heavy intensity. We hypothesized that the time constant for the primary phase [Formula: see text] kinetics was faster in men than in women, for both intensities. Nineteen well trained swimmers (8 females mean ± SD; age 17.9 ± 3.5 years; mass 55.2 ± 3.6 kg; height 1.66 ± 0.05 m and 11 male 21.9 ± 2.8 years; 78.2 ± 11.1 kg; 1.81 ± 0.08 m) performed a discontinuous maximal incremental test and two 600-m square wave transitions for both moderate and heavy intensities to determine the [Formula: see text] kinetics parameters using mono- and bi-exponential models, respectively...
2017: Frontiers in Physiology
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