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JOURNAL ARTICLE
Marcin Straburzyński, Marta Waliszewska-Prosół, Magdalena Nowaczewska, Ewa Katarzyna Czapinska-Ciepiela, Anna Gryglas-Dworak, Slawomir Budrewicz
BACKGROUND: Cranial autonomic symptoms (CASs) include lacrimation, conjunctival injection, rhinorrhea, nasal congestion, facial flushing or sweating, ptosis, and myosis. These symptoms may be associated with trigeminal autonomic cephalalgias (TACs) and migraine. OBJECTIVES: The aim of the study was to assess whether CASs are also reported by patients with frequent episodic tension-type headache (eTTH). MATERIAL AND METHODS: A cross-sectional online survey of a large Polish population was conducted between August 2021 and June 2022...
April 23, 2024: Dental and Medical Problems
#2
JOURNAL ARTICLE
Hardi Vadher, Kristi Baerg MacDonald, Sarah Ross, Julie Aitken Schermer
The Connectorship Scale was designed to assess how leaders connect with their followers and is described to measure eight dimensions: social interactivity, dependability, positive communication, presenting oneself, storytelling ability, belief in networking, tangible introduction, and belief in the importance of online networking. This study explores the scale properties and confirmatory factor analyses (CFA) of the Connectorship Scale and examines how the scale scores correlate with self-efficacy and extraversion based on responses from 454 (52% women) adult business students...
April 23, 2024: Psychological Reports
#3
JOURNAL ARTICLE
Frank Müller, Akhilesh Munagala, Michael J Bouthillier, Jesse I Skok, Harland Holman
BACKGROUND AND OBJECTIVES: Climate change is a major threat to the health of people worldwide. The health care system deals with the immediate health-related effects of climate change and, at the same time, is a major emitter of greenhouse gas. This study aimed to investigate (a) the awareness and perception of climate change among family medicine residency program directors, and (b) the state of climate change education in family medicine residency programs. METHODS: The Council of Academic Family Medicine Educational Research Alliance (CERA) conducted a cross-sectional survey of family medicine program directors in the United States in April 2023...
April 16, 2024: Family Medicine
#4
JOURNAL ARTICLE
Marie Mellerup, Karin Sjöström, Karin Örmon
Psychiatric Day Hospitals offer time-limited active treatment programmes that are therapeutically intensive, coordinated, and with structured clinical services within a stable environment. No previous studies have described patients' experiences of recovery-oriented care at a Psychiatric Day Hospital in a Swedish or Nordic healthcare context. The aim of the study was to explore patients' experiences of a Psychiatric Day Hospital with focus on patient recovery. A qualitative method was used; 12 in-depth interviews were performed with patients all analysed with content analysis...
April 23, 2024: Issues in Mental Health Nursing
#5
JOURNAL ARTICLE
Ben Davies
Sufficientarians face a problem of arbitrariness: why place a sufficiency threshold at any particular point? One response is to seek universal goods to justify a threshold. However, this faces difficulties (despite sincere efforts) by either being too low, or failing to accommodate individuals with significant cognitive disabilities. Some sufficientarians have appealed to individuals' subjective evaluations of their lives. I build on this idea, considering another individualized threshold: 'tolerability'. I respond to some traditional challenges to individualistic approaches to justice: 'expensive' tastes, and adaptive preferences...
August 29, 2023: Ethics, Policy & Environment
#6
JOURNAL ARTICLE
Dickran Kazandjian, Benjamin Diamond, Marios Papadimitriou, Elizabeth Hill, Romanos Sklavenitis-Pistofidis, Bachisio Ziccheddu, Patrick Blaney, Monika Chojnacka, Michael Durante, Kylee Maclachlan, Ryan Young, Saad Usmani, Faith Davies, Gad Getz, Irene Ghobrial, Neha Korde, Gareth Morgan, Francesco Maura, Ola Landgren
PURPOSE: Early intervention for High-Risk Smoldering Multiple Myeloma (HR-SMM) achieves deep and prolonged responses. It is unclear if beneficial outcomes are due to treatment of less complex, susceptible disease or inaccuracy in clinical definition of cases entered. EXPERIMENTAL DESIGN: Here, we interrogated whole genome and whole exome sequencing for 54 patients across two HR-SMM interventional studies (NCT01572480, NCT02279394). RESULTS: We reveal that the genomic landscape of treated HR-SMM is generally simple as compared to Newly Diagnosed (ND)MM counterparts with less inactivation of tumor suppressor genes, RAS pathway mutations, MYC disruption, and APOBEC contribution...
April 23, 2024: Clinical Cancer Research
#7
JOURNAL ARTICLE
Lee Jussim
Because the term "diversity" has two related but different meanings, what authors mean when they use the term is inherently unclear. In its broad form, it refers to vast variety. In its narrow form, it refers to human demographic categories deemed deserving of special attention by social justice-oriented activists. In this article, I review Hommel's critique of Roberts et al. (2020), which, I suggest, essentially constitutes two claims: that Roberts et al.'s (2020) call for diversity in psychological science focuses exclusively on the latter narrow form of diversity and ignores the scientific importance of diversity in the broader sense, and ignoring diversity in the broader sense is scientifically unjustified...
May 2024: Perspectives on Psychological Science
#8
JOURNAL ARTICLE
Steven Othello Roberts
In the spirit of America's Shakespeare, August Wilson (1997), I have written this article as a testimony to the conditions under which I, and too many others, engage in scholarly discourse. I hope to make clear from the beginning that although the ideas presented here are not entirely my own-as they have been inherited from the minority of scholars who dared and managed to bring the most necessary, unpalatable, and unsettling truths about our discipline to the broader scientific community-I do not write for anyone but myself and those scholars who have felt similarly marginalized, oppressed, and silenced...
May 2024: Perspectives on Psychological Science
#9
JOURNAL ARTICLE
Federica I Wolf, Valentina Trapani
Since the start of the COVID-19 pandemic, it has become increasingly clear that the disease can have relevant multisystemic and long-term effects, and several studies have attempted to identify key determinants of the disease course. Here we discuss recent evidence suggesting that, in long COVID patients, combined magnesium and vitamin D deficiencies associate with a higher number of clinical manifestations, as compared to patients with normal levels of both nutrients. We highlight the potential synergistic effects of these deficiencies and propose that future studies should explore a causal link with the risk of developing long COVID...
April 23, 2024: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
#10
JOURNAL ARTICLE
Soo Heon Kwak, Ryan B Hernandez-Cancela, Daniel A DiCorpo, David E Condon, Jordi Merino, Peitao Wu, Jennifer A Brody, Jie Yao, Xiuqing Guo, Fariba Ahmadizar, Mariah Meyer, Murat Sincan, Josep M Mercader, Sujin Lee, Jeffrey Haessler, Ha My T Vy, Zhaotong Lin, Nicole D Armstrong, Shaopeng Gu, Noah L Tsao, Leslie A Lange, Ningyuan Wang, Kerri L Wiggins, Stella Trompet, Simin Liu, Ruth J F Loos, Renae Judy, Philip H Schroeder, Natalie R Hasbani, Maxime M Bos, Alanna C Morrison, Rebecca D Jackson, Alexander P Reiner, JoAnn E Manson, Ninad S Chaudhary, Lynn K Carmichael, Yii-Der Ida Chen, Kent D Taylor, Mohsen Ghanbari, Joyce van Meurs, Achilleas N Pitsillides, Bruce M Psaty, Raymond Noordam, Ron Do, Kyong Soo Park, J Wouter Jukema, Maryam Kavousi, Adolfo Correa, Stephen S Rich, Scott M Damrauer, Catherine Hajek, Nam H Cho, Marguerite R Irvin, James S Pankow, Girish N Nadkarni, Robert Sladek, Mark O Goodarzi, Jose C Florez, Daniel I Chasman, Susan R Heckbert, Charles Kooperberg, Josée Dupuis, Rajeev Malhotra, Paul S de Vries, Ching-Ti Liu, Jerome I Rotter, James B Meigs
OBJECTIVE: To identify genetic risk factors for incident cardiovascular disease (CVD) among people with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS: We conducted a multiancestry time-to-event genome-wide association study for incident CVD among people with T2D. We also tested 204 known coronary artery disease (CAD) variants for association with incident CVD. RESULTS: Among 49,230 participants with T2D, 8,956 had incident CVD events (event rate 18...
April 23, 2024: Diabetes Care
#11
JOURNAL ARTICLE
Allen Green, Elijah R Sommer, Max R Johnson, Hector Gonzalez, Twan Sia, David A Spain, Jeff Choi
OBJECTIVE: Determine the proportion of contemporary US academic general surgery residency program graduates who pursue academic careers and identify factors associated with pursuing academic careers. SUMMARY BACKGROUND DATA: Many academic residency programs aim to cultivate academic surgeons, yet the proportion of contemporary graduates who choose academic careers is unclear. The potential determinants that affect graduates' decisions to pursue academic careers remain underexplored...
April 23, 2024: Annals of Surgery
#12
JOURNAL ARTICLE
Sepehr Shirani, Bahman Abdi-Sargezeh, Antonio Valentin, Gonzalo Alarcon, Jordan Bird, Saeid Sanei
Identification of seizure sources in the brain is of paramount importance, particularly for drug-resistant epilepsy patients who may require surgical operation. Interictal epileptiform discharges (IEDs), which may or may not be frequent, are known to originate from seizure networks. Delayed responses (DRs) to brain electrical stimulation have been recently discovered. If DRs and IEDs come from the same location and the DRs can be accurately localized, there will be a significant step in identification of the seizure sources...
April 23, 2024: IEEE Transactions on Bio-medical Engineering
#13
JOURNAL ARTICLE
Zehong Wang, Donghua Yu, Shigen Shen, Shichao Zhang, Huawen Liu, Shuang Yao, Maozu Guo
Contrastive learning (CL) has emerged as a powerful approach for self-supervised learning. However, it suffers from sampling bias, which hinders its performance. While the mainstream solutions, hard negative mining (HNM) and supervised CL (SCL), have been proposed to mitigate this critical issue, they do not effectively address graph CL (GCL). To address it, we propose graph positive sampling (GPS) and three contrastive objectives. The former is a novel learning paradigm designed to leverage the inherent properties of graphs for improved GCL models, which utilizes four complementary similarity measurements, including node centrality, topological distance, neighborhood overlapping, and semantic distance, to select positive counterparts for each node...
April 23, 2024: IEEE Transactions on Neural Networks and Learning Systems
#14
JOURNAL ARTICLE
Yue Zhao, Yantao Shen, Yuanjun Xiong, Shuo Yang, Wei Xia, Zhuowen Tu, Bernt Schiele, Stefano Soatto
Negative flips are errors introduced in a classification system when a legacy model is updated. Existing methods to reduce the negative flip rate (NFR) either do so at the expense of overall accuracy by forcing a new model to imitate the old models, or use ensembles, which multiply inference cost prohibitively. We analyze the role of ensembles in reducing NFR and observe that they remove negative flips that are typically not close to the decision boundary, but often exhibit large deviations in the distance among their logits...
April 23, 2024: IEEE Transactions on Pattern Analysis and Machine Intelligence
#15
JOURNAL ARTICLE
A Jay Freeman, Michael R Narkewicz
No abstract text is available yet for this article.
April 23, 2024: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
#16
JOURNAL ARTICLE
Emma Soneson, Emma Howarth, Alison Weir, Peter B Jones, Mina Fazel
BACKGROUND: Schools in the United Kingdom and elsewhere are expected to protect and promote pupil mental health. However, many school staff members do not feel confident in identifying and responding to pupil mental health difficulties and report wanting additional training in this area. OBJECTIVE: We aimed to explore the feasibility of Kognito's At-Risk for Elementary School Educators, a brief, interactive web-based training program that uses a simulation-based approach to improve school staff's knowledge and skills in supporting pupil mental health...
April 23, 2024: Journal of Medical Internet Research
#17
RANDOMIZED CONTROLLED TRIAL
Ioana Latu, Nastasia Sălăgean, Torill M B Larsen, Andreea Bogdana Isbasoiu, Florin Alin Sava
BACKGROUND: Repeated stigmatization due to group membership constitutes a recurrent stressor with negative impact on physical and mental health (minority stress model). Among European countries, Romania ranks low on LGBT+ (lesbian, gay, bisexual, and transgender people. The "+" represents individuals whose identities do not fit typical binary notions of male and female [nonbinary]) inclusion, with 45% of Romanian LGBT+ respondents reporting discrimination in at least 1 area of life in the year preceding the survey...
April 23, 2024: JMIR Research Protocols
#18
JOURNAL ARTICLE
Emma Grace Carey, Faith Oluwasemilore Adeyemi, Lakshmi Neelakantan, Blossom Fernandes, Mina Fazel, Tamsin Ford, Anne-Marie Burn
BACKGROUND: Improving access to mental health data to accelerate research and improve mental health outcomes is a potentially achievable goal given the substantial data that can now be collected from mobile devices. Smartphones can provide a useful mechanism for collecting mental health data from young people, especially as their use is relatively ubiquitous in high-resource settings such as the United Kingdom and they have a high capacity to collect active and passive data. This raises the interesting opportunity to establish a large bank of mental health data from young people that could be accessed by researchers worldwide, but it is important to clarify how to ensure that this is done in an appropriate manner aligned with the values of young people...
April 23, 2024: JMIR Formative Research
#19
JOURNAL ARTICLE
Adam R Evans, Joseph Mulholland, Michael J Lewis, Ping Hu
Peptide mapping with mass spectrometry (MS) is an important tool for protein characterization in the biopharmaceutical industry. Historically, peptide mapping monitors post-translational modifications (PTMs) of protein products and process intermediates during development. Multi-attribute monitoring (MAM) methods have been used previously in commercial release and stability testing panels to ensure control of selected critical quality attributes (CQAs). Our goal is to use MAM methods as part of an overall analytical testing strategy specifically focused on CQAs, while removing or replacing historical separation methods that do not effectively distinguish CQAs from non-CQAs due to co-elution...
2024: MAbs
#20
JOURNAL ARTICLE
Kiran Sidhu, Younghoon Kwon
No abstract text is available yet for this article.
April 23, 2024: European Heart Journal. Acute Cardiovascular Care
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