keyword
MENU ▼
Read by QxMD icon Read
search

canine distemper virus

keyword
https://www.readbyqxmd.com/read/29316493/transmission-of-morbilliviruses-within-and-among-marine-mammal-species
#1
REVIEW
Wendy K Jo, Albert Dme Osterhaus, Martin Ludlow
Transmission of morbilliviruses within and among marine mammal species has been documented in a variety of marine habitats. Cetacean morbillivirus spreads between cetacean species in the aquatic environment whereas both phocine distemper virus and canine distemper virus have been associated with transmission within and between pinniped and terrestrial carnivore species in their natural habitat and at the aquatic-terrestrial interface. Periodically these viruses have caused large epizootics involving thousands of animals, due to sustained intra-species virus transmission...
January 6, 2018: Current Opinion in Virology
https://www.readbyqxmd.com/read/29297815/serologic-response-to-canine-distemper-vaccination-in-captive-linnaeus-s-two-toed-sloths-choloepus-didactylus-after-a-fatal-canine-distemper-virus-outbreak
#2
Julie D Sheldon, Andrew C Cushing, Rebecca P Wilkes, Eman Anis, Edward J Dubovi
Canine distemper virus (CDV) affects many wild and captive, nondomestic species worldwide but has not been previously reported in Xenarthra. Paucity of information on vaccination safety and efficacy presents challenges for disease prevention in captive collections. CDV infections and subsequent mortalities in five captive Linnaeus's two-toed sloths ( Choloepus didactylus) in eastern Tennessee are reported. Clinical signs included oculonasal discharge, oral ulcerations, and diarrhea, and the diagnosis was confirmed by necropsy, histopathology, immunohistochemistry, virus isolation, and polymerase chain reaction...
December 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29297812/canine-distemper-in-a-vaccinated-snow-leopard-panthera-uncia
#3
Sathya K Chinnadurai, Michael J Kinsel, Michael J Adkesson, Karen Terio
A 6-yr-old male snow leopard ( Panthera uncia) presented with acute seizures, hyperthermia, and tachypnea. Because of a diagnosis of anuric renal failure, the animal was euthanized. On histopathologic examination, numerous intralesional intracytoplasmic and intranuclear inclusions were found in the lungs, lymph nodes, and stomach. Positive immunohistochemical staining for canine distemper virus (CDV) was found in the lungs and, to a lesser extent, in the lymph nodes and brain. Molecular testing yielded a CDV H gene sequence that was closely related to CDV isolates concurrently found in wild raccoons from adjacent forested areas...
December 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29284384/comparison-of-reverse-transcription-real-time-pcr-and-immunohistochemistry-for-the-detection-of-canine-distemper-virus-infection-in-raccoons-in-ontario-canada
#4
Nicole M Nemeth, Paul T Oesterle, G Douglas Campbell, Davor Ojkic, Claire M Jardine
Canine distemper virus (CDV) is a widespread morbillivirus that causes subclinical to fatal infections in domestic and wild carnivores. Raccoons ( Procyon lotor) are CDV reservoirs and suffer from associated disease. Aspects of pathogenesis may lead to difficulty in the interpretation of commonly used testing modalities, such as reverse-transcription real-time (RT-rt)PCR and immunohistochemistry (IHC). The reliance upon such tests is greater for wildlife, which are often submitted as carcasses with no clinical history...
December 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29186969/neuronal-and-astrocytic-involvement-in-striped-dolphins-stenella-coeruleoalba-with-morbilliviral-encephalitis
#5
R Lucá, R Giacominelli-Stuffler, S Mazzariol, S Roperto, C Cocumelli, G DI Guardo
Dolphin morbillivirus (DMV), a highly pathogenic agent, may cause peculiar, "brain-only" forms of infection (BOFDI), in which viral antigen and/or genome is found exclusively in the brain from striped dolphins (Stenella coeruleoalba). These BOFDIs show morphopathological similarities with subacute sclerosing panencephalitis and old dog encephalitis (ODE) in measles virus-infected patients and in canine distemper virus-infected dogs, respectively. The brain tissue from 3 BOFDI-affected striped dolphins was investigated by means of double labelling-indirect immunofluorescence (DL-IIF) and ultrastructurally, in order to characterize the DMV-targeted neuronal and non-neuronal cell populations, along with the associated submicroscopic findings...
2017: Acta Virologica
https://www.readbyqxmd.com/read/29185877/evaluation-of-a-direct-immunofluorescent-assay-and-or-conjunctival-cytology-for-detection-of-canine-distemper-virus-antigen
#6
Labrini V Athanasiou, Maria C Kantere, Constantinos S Kyriakis, Dimitra Pardali, Katerina Adamama Moraitou, Zoe S Polizopoulou
Canine distemper is a common and potentially lethal multisystemic disease caused by the Canine distemper virus (CDV). We evaluated the diagnostic performance of direct immunofluorescent assay (FA) and cytology to detect CDV antigen in conjunctival cells compared with an established polymerase chain reaction (PCR) detection assay used as a gold standard for CDV diagnosis. Samples were collected from 57 young dogs presenting with central nervous system signs compatible with distemper disease. Exfoliative epithelial cells were collected from the right and left conjunctiva of each animal using nylon-bristled cytobrushes for cytology and cotton swabs for FA and PCR...
November 29, 2017: Viral Immunology
https://www.readbyqxmd.com/read/29173585/european-surveillance-of-emerging-pathogens-associated-with-canine-infectious-respiratory-disease
#7
Judy A Mitchell, Jacqueline M Cardwell, Heather Leach, Caray A Walker, Sophie Le Poder, Nicola Decaro, Miklos Rusvai, Herman Egberink, Peter Rottier, Mireia Fernandez, Eirini Fragkiadaki, Shelly Shields, Joe Brownlie
Canine infectious respiratory disease (CIRD) is a major cause of morbidity in dogs worldwide, and is associated with a number of new and emerging pathogens. In a large multi-centre European study the prevalences of four key emerging CIRD pathogens; canine respiratory coronavirus (CRCoV), canine pneumovirus (CnPnV), influenza A, and Mycoplasma cynos (M. cynos); were estimated, and risk factors for exposure, infection and clinical disease were investigated. CIRD affected 66% (381/572) of the dogs studied, including both pet and kennelled dogs...
December 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/29173050/measles-vaccination-threat-from-related-veterinary-viruses-and-need-for-continued-vaccination-post-measles-eradication
#8
Sara Louise Cosby, Leanne Weir
Measles virus (MV) is the only human virus within the morbillivirus genus of the Paramyxoviridae. The veterinary members are canine distemper virus (CDV), peste des petits ruminants virus (PPRV), Rinderpest Virus (RPV) as well as the marine morbilliviruses phocine distemper virus (PDV), dolphin morbillivirus (DMV) and porpoise morbillivirus (PMV). Morbilliviruses have a severe impact on humans and animal species. They confer diseases which have contributed to morbidity and mortality of the population on a global scale...
November 27, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29146026/vaccination-of-ferrets-for-rabies-and-distemper
#9
REVIEW
Laura L Wade
Companion ferrets need to be vaccinated against 2 viral diseases that cause neurologic illness: canine distemper and rabies. Although not common in ferrets, both viruses are fatal in ferrets and rabies virus is also fatal in humans. In this article, we provide a basic review of the 2 diseases, highlighting key neurologic concerns. We also review and update current vaccine concerns from a practitioner's perspective, including available vaccines, vaccine schedule recommendations, vaccine reactions, and risk assessment...
January 2018: Veterinary Clinics of North America. Exotic Animal Practice
https://www.readbyqxmd.com/read/29102126/development-of-cdv-specific-monoclonal-antibodies-for-differentiation-of-variable-epitopes-of-nucleocapsid-protein
#10
Zhenwei Bi, Yongshan Wang, Qunxing Pan, Xingxia Xia, Libo Xu
The highly contagious canine distemper viruses (CDVs) are still a major threat to a wide range of natural susceptible hosts. The nucleocapsid (N) protein plays various roles in the virus-induced immune response. But precise mapping of epitopes and antigenic variations in N protein of CDV are still scant. In this study, two monoclonal antibodies (MAbs), designated as F8N and G3N, against the N protein of CDV were generated and characterized. The epitopes recognized by the two MAbs were mapped by truncated N protein fragments expressed in E...
November 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/29056700/how-behavioral-changes-can-indicate-serious-cerebral-pathology-a-case-report-of-concomitant-olfactory-neuroblastoma-and-distemper-virus-encephalitis-in-a-swiss-shepherd-dog
#11
Dario Candini, Ilaria Biasato, Paulo Ricardo Dell'Armelina Rocha, Elena Grego, Maria Teresa Capucchio, Cristina Vercelli
Behavioral alterations in dogs are not easy to understand and cure. The situation is more difficult when an encephalitis due to Canine Distemper Virus (CDV) and a concomitant olfactory neuroblastoma are present. This case report deals with the story of a 5-year-old Swiss shepherd dog with behavioral changes, seizures, epistaxis and ataxia. Following clinical and laboratory exams, a suspected diagnosis of CDV infection was hypothesized, and a therapy based on Ω-interferon was administered. Every supporting therapy failed and the worsening of the clinical conditions led to the euthanasia of the patient...
August 28, 2017: Veterinary Sciences
https://www.readbyqxmd.com/read/29053427/canine-distemper-virus-in-a-wild-far-eastern-leopard-panthera-pardus-orientalis
#12
Nadezhda S Sulikhan, Martin Gilbert, Ekaterina Yu Blidchenko, Sergei V Naidenko, Galina V Ivanchuk, Tatiana Yu Gorpenchenko, Mikhail V Alshinetskiy, Elena I Shevtsova, John M Goodrich, John C M Lewis, Mikhail S Goncharuk, Olga V Uphyrkina, Vyatcheslav V Rozhnov, Sergey V Shedko, Denise McAloose, Dale G Miquelle
The critically endangered population of Far Eastern leopards (Panthera pardus orientalis) may number as few as 60 individuals and is at risk from stochastic processes such as infectious disease. During May 2015, a case of canine distemper virus (CDV) was diagnosed in a wild leopard exhibiting severe neurologic disease in the Russian territory of Primorskii Krai. Amplified sequences of the CDV hemagglutinin gene and phosphoprotein gene aligned within the Arctic-like clade of CDV, which includes viruses from elsewhere in Russia, China, Europe, and North America...
October 20, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28962633/identification-of-a-novel-linear-b-cell-epitope-using-a-monoclonal-antibody-against-the-carboxy-terminus-of-the-canine-distemper-virus-nucleoprotein-and-sequence-analysis-of-the-identified-epitope-in-different-cdv-isolates
#13
Li Yi, Zhigang Cao, Mingwei Tong, Yuening Cheng, Yong Yang, Shuang Li, Jianke Wang, Peng Lin, Yaru Sun, Miao Zhang, Shipeng Cheng
BACKGROUND: The Nucleoprotein (NP) is the most abundant and highly immunogenic protein in canine distemper virus (CDV), playing an important role in CDV viral replication and assembly. RESULTS: In this study, a specific monoclonal antibody, named C8, was produced against the NP protein C terminal (amino acids 401-523). A linear N protein epitope was identified by subjecting a series of partially overlapping synthesized peptides to enzyme-linked immunosorbent assay (ELISA) analysis...
September 29, 2017: Virology Journal
https://www.readbyqxmd.com/read/28919674/prevalence-of-enteropathogens-and-their-antibiotic-sensitivity-pattern-in-puppies-with-hemorrhagic-gastroenteritis
#14
A Kokila Priya, M Balagangatharathilagar, D Chandrasekaran, M Parthiban, S Prathaban
AIM: Hemorrhagic gastroenteritis (HGE) ranging from mild to severe forms is commonly encountered in puppies. The aim of the study was to identify the prevalence of common enteropathogens and the antibiotic sensitivity pattern in puppies reported with HGE. MATERIALS AND METHODS: The canine HGE activity index, with little modification, was adopted to identify Grade III/severely affected puppies below 6 months of age. Fecal polymerase chain reaction (PCR) assay was employed to screen and compare the enteropathogens in puppies with hemorrhagic diarrhea and healthy control...
August 2017: Veterinary World
https://www.readbyqxmd.com/read/28895871/type-i-interferons-in-the-pathogenesis-and-treatment-of-canine-diseases
#15
REVIEW
Daniela Klotz, Wolfgang Baumgärtner, Ingo Gerhauser
Type I interferons (IFNs) such as IFN-α, IFN-β, IFN-ε, IFN-κ, and IFN-ω represent cytokines, which are deeply involved in the regulation and activation of innate and adaptive immune responses. They possess strong antiviral, antiproliferative, and immunomodulatory activities allowing their use in the therapy of different viral diseases, neoplasms, and immune-mediated disorders, respectively. Initially, treatment strategies were based on nonspecific inducers of type I IFNs, which were soon replaced by different recombinant proteins...
September 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/28888886/the-recombinant-ehv-1-vector-producing-cdv-hemagglutinin-as-potential-vaccine-against-canine-distemper
#16
Zihao Pan, Jin Liu, Jiale Ma, Qiuli Jin, Huochun Yao, Nikolaus Osterrieder
Canine distemper virus (CDV), is a pantropic agent of morbillivirus that causes fetal disease in dogs. Base on a broad host rang of CDV, the continued vaccines inoculation is unavoidable to pose gene recombination risk in vaccine virus and wild virus. The current study presents the construction of novel vectors, using equine herpesvirus type 1 (EHV-1) expressing the canine distemper virus (CDV). The recent field strain hemagglutinin protein and nucleoprotein were used for the construction of the viral vector vaccines...
October 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28811626/outbreak-and-genotyping-of-canine-distemper-virus-in-captive-siberian-tigers-and-red-pandas
#17
He Zhang, Fen Shan, Xia Zhou, Bing Li, Jun-Qiong Zhai, Shu-Zhan Zou, Meng-Fan Wu, Wu Chen, Shao-Lun Zhai, Man-Lin Luo
In this study, four canine distemper virus (CDV) strains were isolated from captive Siberian tigers (Panthera tigris altaica) and red pandas (Ailurus fulgens) during two separate CDV outbreaks in a zoo in Guangdong province, China. Sequence alignment and phylogenetic analyses based on the full-length hemagglutinin (H) and fusion (F) genes showed that they were closely identical to genotype Asia-1. Prior to confirmation of CDV in Siberian tigers, to control spread of the disease, a live attenuated combination CDV vaccine was used among almost all carnivore animals except for red pandas in which another recombinant combination CDV vaccine was used...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28810858/rapid-and-sensitive-detection-of-canine-distemper-virus-by-real-time-reverse-transcription-recombinase-polymerase-amplification
#18
Jianchang Wang, Jinfeng Wang, Ruiwen Li, Libing Liu, Wanzhe Yuan
BACKGROUND: Canine distemper, caused by Canine distemper virus (CDV), is a highly contagious and fatal systemic disease in free-living and captive carnivores worldwide. Recombinase polymerase amplification (RPA), as an isothermal gene amplification technique, has been explored for the molecular detection of diverse pathogens. METHODS: A real-time reverse transcription RPA (RT-RPA) assay for the detection of canine distemper virus (CDV) using primers and exo probe targeting the CDV nucleocapsid protein gene was developed...
August 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28760649/ribavirin-and-boceprevir-are-able-to-reduce-canine-distemper-virus-growth-in-vitro
#19
Gianvito Lanave, Alessandra Cavalli, Vito Martella, Tommaso Fontana, Ruggero Losappio, Maria Tempesta, Nicola Decaro, Domenico Buonavoglia, Michele Camero
Canine distemper virus (CDV) is a major infectious disease of dogs. Although vaccines were successful to control CDV spread in canine population, the disease is still common and may pose a threat to unvaccinated dogs. In the attempt to develop specific anti-viral therapeutic tools, the efficacy of several molecules against CDV has been investigated in vitro. In this study the antiviral efficacy in vitro against CDV of ribavirin and boceprevir alone or in combination was evaluated. CDV growth in VERO cells was inhibited by ribavirin, by boceprevir and by a combination of the two molecules at non-cytotoxic concentrations, as evaluated by end-point viral titration in cell monolayers and by quantification of viral RNA using quantitative RT-PCR...
October 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/28751224/molecular-cloning-and-functional-characterization-of-eleven-subtypes-of-interferon-%C3%AE-in-amur-tigers-panthera-tigris-altaica
#20
Hongjing Zhao, Jian Ma, Yu Wang, Juanjuan Liu, Yizhi Shao, Jinglun Li, Guangshun Jiang, Mingwei Xing
Interferon has a broad-spectrum of antiviral effects and represents an ideal choice for the development of antiviral drugs. Nonetheless, information about alpha interferon (IFN-α) is vacant in Amur tiger (Panthera tigris altaica), an endangered species and indigenous to northeast Asia. Herein, 11 PtIFN-αs genes, which encoded proteins of 164-165 amino acids, were amplified. Afterwards, expression and purification were conducted in Escherichia coli. In physicochemical analysis, PtIFN-αs were shown to be highly sensitive to trypsin and remained stable despite changes in pH and temperature...
July 24, 2017: Developmental and Comparative Immunology
keyword
keyword
39573
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"