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canine distemper virus

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https://www.readbyqxmd.com/read/29717641/eastern-equine-encephalitis-in-puppies-in-michigan-and-new-york-states
#1
Caroline Andrews, Jodie Gerdin, Jon Patterson, Elizabeth L Buckles, Scott D Fitzgerald
Eastern equine encephalitis virus (EEEV) is classified as a select agent and is capable of causing mortality in humans and a number of veterinary species. Herein, we describe 3 cases of EEE in puppies in Michigan and New York. Two puppies were euthanized following an acute history of seizures and obtundation. A littermate of one of these puppies died 2 wk earlier following a history of anorexia and fever. All 3 puppies lacked significant gross anatomic lesions at autopsy and tested negative for rabies virus...
April 1, 2018: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29698496/frequency-of-exposure-of-endangered-caspian-seals-to-canine-distemper-virus-leptospira-interrogans-and-toxoplasma-gondii
#2
Somayeh Namroodi, Amir S Shirazi, Seyyed Reza Khaleghi, James N Mills, Vahid Kheirabady
Canine distemper virus (CDV), Leptospira interrogans, and Toxoplasma gondii are potentially lethal pathogens associated with decline in marine mammal populations. The Caspian Sea is home for the endangered Caspian seal (Pusa caspica). In the late 1990s and early 2000s, CDV caused a series of mortality events involving at least several thousand Caspian seals. To assess current infection status in Caspian seals, we surveyed for antibodies to three pathogens with potential to cause mortality in marine mammals...
2018: PloS One
https://www.readbyqxmd.com/read/29695673/molecular-surveillance-of-canine-distemper-virus-in-diarrhoetic-puppies-in-northeast-china-from-may-2014-to-april-2015
#3
Chunqiu Li, Donghua Guo, Rui Wu, Fanzhi Kong, Junjun Zhai, Dongwei Yuan, Dongbo Sun
To trace the prevalence of canine distemper virus (CDV) in diarrhoetic dogs, a total of 201 stool samples were collected in the Heilongjiang province of northeastern China from May 2014 to April 2015. The 201 fecal samples were subjected to the detection of CDV by using RT-PCR targeting the partial N gene, phylogenetic analysis based on the complete H gene, and co-infection analysis. Results indicated that 24.88% (50/201) of the samples were positive for CDV. The fifty CDV samples exhibited an overall co-infection rate of 94% (47/50) with four enteric viruses (82%, 41/50) and five bacteria (72%, 36/50)...
April 24, 2018: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29675651/a-multiplex-pcr-method-for-the-simultaneous-detection-of-three-viruses-associated-with-canine-viral-enteric-infections
#4
Xiaoyu Deng, Jiali Zhang, Jiazi Su, Hao Liu, Yanlong Cong, Lei Zhang, Kemeng Zhang, Ning Shi, Rongguang Lu, Xijun Yan
The aim of this study was to establish a multiplex PCR (mPCR) method that can simultaneously detect canine parvovirus (CPV-2), canine coronavirus (CCoV) and canine adenovirus (CAV), thereby eliminating the need to detect these pathogens individually. Based on conserved regions in the genomes of these three viruses, the VP2 gene of CPV-2, the endoribonuclease nsp15 gene of CCoV, and the 52K gene of CAV were selected for primer design. The specificity of the mPCR results showed no amplification of canine distemper virus (CDV), canine parainfluenza virus (CPIV), or pseudorabies virus (PRV), indicating that the method had good specificity...
April 19, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29588198/identification-of-enteric-viruses-circulating-in-a-dog-population-with-low-vaccine-coverage
#5
Christian D B T Alves, Oscar F O Granados, Renata da F Budaszewski, André F Streck, Matheus N Weber, Samuel P Cibulski, Luciane D Pinto, Nilo Ikuta, Cláudio W Canal
Although the use of vaccines has controlled enteric diseases in dogs in many developed countries, vaccine coverage is still under optimal situation in Brazil. There is a large population of nonimmunized dogs and few studies about the identification of the viruses associated with diarrhea. To address this situation, stool samples from 325 dogs were analyzed by polymerase chain reaction for the detection of common enteric viruses such as Canine adenovirus (CAdV), Canine coronavirus (CCoV), Canine distemper virus (CDV), Canine rotavirus (CRV) and Carnivorous protoparvovirus 1 (canine parvovirus 2; CPV-2)...
March 15, 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29570709/disentangling-factors-that-shape-the-gut-microbiota-in-german-shepherd-dogs
#6
Åsa Vilson, Ziad Ramadan, Qinghong Li, Åke Hedhammar, Arleigh Reynolds, Julie Spears, Jeff Labuda, Robyn Pelker, Bengt Björkstén, Johan Dicksved, Helene Hansson-Hamlin
The aim of this study was to explore the development of the gut microbiota in 168 German Shepherd dogs (30 litters) from 7 weeks to 18 months of age and furthermore, to study the effect of relatedness, maternal microbiota composition and living environment in a large and well-defined population of dogs. Using 454 pyrosequencing, we assessed the effects of pre- and postnatal probiotic supplementation (Lactobacillus johnsonii NCC533 (La1)) and analysed whether administration of the probiotic strain influenced fecal microbiota composition in a placebo controlled double-blinded study...
2018: PloS One
https://www.readbyqxmd.com/read/29558524/survival-of-viral-pathogens-in-animal-feed-ingredients-under-transboundary-shipping-models
#7
Scott A Dee, Fernando V Bauermann, Megan C Niederwerder, Aaron Singrey, Travis Clement, Marcelo de Lima, Craig Long, Gilbert Patterson, Maureen A Sheahan, Ana M M Stoian, Vlad Petrovan, Cassandra K Jones, Jon De Jong, Ju Ji, Gordon D Spronk, Luke Minion, Jane Christopher-Hennings, Jeff J Zimmerman, Raymond R R Rowland, Eric Nelson, Paul Sundberg, Diego G Diel
The goal of this study was to evaluate survival of important viral pathogens of livestock in animal feed ingredients imported daily into the United States under simulated transboundary conditions. Eleven viruses were selected based on global significance and impact to the livestock industry, including Foot and Mouth Disease Virus (FMDV), Classical Swine Fever Virus (CSFV), African Swine Fever Virus (ASFV), Influenza A Virus of Swine (IAV-S), Pseudorabies virus (PRV), Nipah Virus (NiV), Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), Swine Vesicular Disease Virus (SVDV), Vesicular Stomatitis Virus (VSV), Porcine Circovirus Type 2 (PCV2) and Vesicular Exanthema of Swine Virus (VESV)...
2018: PloS One
https://www.readbyqxmd.com/read/29557180/evaluation-of-a-community-s-risk-for-canine-parvovirus-and-distemper-using-antibody-testing-and-gis-mapping-of-animal-shelter-intakes
#8
Miranda E Spindel, Matthew R Krecic, Margaret R Slater, Nicole Vigil
This cross-sectional study aimed to identify where dogs with negative antibody tests to canine parvovirus (CPV) and canine distemper virus (CDV) originated when entering a community shelter, using a commercially available ELISA antibody test and Geographic Information Systems mapping. Of 2745 canines entering during a three-month period, 1056 test results were obtained. Dogs or puppies weighing over 2 lb were eligible if they could be humanely, nonchemically restrained for phlebotomy. Age and minor health issues weren't exclusions...
March 20, 2018: Journal of Applied Animal Welfare Science: JAAWS
https://www.readbyqxmd.com/read/29517402/frequency-of-virus-coinfection-in-raccoons-procyon-lotor-and-striped-skunks-mephitis-mephitis-during-a-concurrent-rabies-and-canine-distemper-outbreak
#9
Claire M Jardine, Tore Buchanan, Davor Ojkic, G Douglas Campbell, Jeff Bowman
Rabies and canine distemper virus infections in wildlife share similar presenting signs. Canine distemper virus was detected using real-time PCR of conjunctival swabs in rabies positive raccoons (22/32) and skunks (7/34) during a concurrent rabies and canine distemper outbreak in Ontario, Canada in 2015-2016. Coinfections with both viruses should be considered, particularly in distemper endemic areas that are at risk of rabies incursion.
March 8, 2018: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/29499233/a-multiplex-taqman-real-time-pcr-for-detection-and-differentiation-of-four-antigenic-types-of-canine-parvovirus-in-china
#10
Yaru Sun, Yuening Cheng, Peng Lin, Li Yi, Mingwei Tong, Zhigang Cao, Gaili Wang, Shuang Li, Shipeng Cheng, Wanzhe Yuan, Jianke Wang
Canine parvovirus (CPV) is an important pathogen in domestic dogs, and the original antigenic types CPV-2 and its variants, CPV-2a, 2b and 2c, are prevalent worldwide. A multiplex TaqMan real-time PCR method was developed for the detection and differentiation of four antigenic types of CPV. A set of primers and probes, CPV-305F/CPV-305R and CPV-2-305P (for CPV-2)/CPV-2a-305P (for CPV-2a, 2b and 2c), was able to differentiate CPV-2 and its variants (CPV-2a, 2b and 2c). Another set of primers and probes, CPV-426F/CPV-426R and CPV-2-426P (for CPV-2 and 2a)/CPV-2b-426P (for CPV-2b)/CPV-2c-426P (for CPV-2c), was able to differentiate CPV-2a (2), CPV-2b, and CPV-2c...
April 2018: Molecular and Cellular Probes
https://www.readbyqxmd.com/read/29498900/evidence-of-two-cocirculating-canine-distemper-virus-strains-in-mesocarnivores-from-northern-colorado
#11
Darren J Wostenberg, Nikki Walker, Karen A Fox, Terry R Spraker, Antoinette J Piaggio, Amy Gilbert
Canine distemper virus (CDV) is a highly contagious pathogen that principally infects wildlife and domestic carnivores. Peridomestic species such as raccoons ( Procyon lotor) experience outbreaks with high mortality. Clinical signs of infection include anorexia, fever, respiratory infection, and neurologic complications. Although not zoonotic, CDV poses a high risk to unvaccinated domestic animals and the conservation of endangered species. During 2013-2016, we opportunistically collected wild and domestic carnivore specimens through a rabies surveillance program in northern Colorado...
March 2, 2018: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/29475511/the-canine-mhc-class-ia-allele-dla-88-508-01-presents-diverse-self-and-canine-distemper-virus-origin-peptides-of-varying-length-that-have-a-conserved-binding-motif
#12
Peter Ross, Paige S Nemec, Alexander Kapatos, Keith R Miller, Jennifer C Holmes, Steven E Suter, Adam S Buntzman, Erik J Soderblom, Edward J Collins, Paul R Hess
Ideally, CD8+ T-cell responses against virally infected or malignant cells are defined at the level of the specific peptide and restricting MHC class I element, a determination not yet made in the dog. To advance the discovery of canine CTL epitopes, we sought to determine whether a putative classical MHC class Ia gene, Dog Leukocyte Antigen (DLA)-88, presents peptides from a viral pathogen, canine distemper virus (CDV). To investigate this possibility, DLA-88*508:01, an allele prevalent in Golden Retrievers, was expressed as a FLAG-tagged construct in canine histiocytic cells to allow affinity purification of peptide-DLA-88 complexes and subsequent elution of bound peptides...
March 2018: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/29456114/detection-and-genetic-characterization-of-mamastrovirus-5-from-brazilian-dogs
#13
Christian D B T Alves, Renata F Budaszewski, Marcela Torikachvili, André F Streck, Matheus N Weber, Samuel P Cibulski, Ana P Ravazzolo, Vagner R Lunge, Cláudio W Canal
Mamastrovirus 5 (MAstV5), belonging to the Astroviridae (AstV) family, previously known as canine astrovirus or astrovirus-like particles, has been reported in several countries to be associated with viral enteric disease in dogs since the 1980s. Astroviruses have been detected in fecal samples from a wide variety of mammals and birds that are associated with gastroenteritis and extra enteric manifestations. In the present study, RT-PCR was used to investigate the presence of MAstV5 in 269 dog fecal samples...
February 2, 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29421305/molecular-characterization-of-complete-genome-of-a-canine-distemper-virus-associated-with-fatal-infection-in-dogs-in-gabon-central-africa
#14
Gael D Maganga, Ingrid Labouba, Barthélémy Ngoubangoye, Andriniaina A Nkili-Meyong, Daniel Obame Ondo, Eric M Leroy, Nicolas Berthet
Canine distemper (CD) is the most deadly disease in dogs with mortality rates reaching 50%. The pathological agent, the CD virus (CDV), generally causes a severe systemic disease, although the nervous form can coexist with the acute catarrhal form in the same individual. In this study, we describe an outbreak of 18 cases of CD that occurred in 2015 in a German Shepherd dog population in northwestern Gabon. In addition, we determined the sequence of the CDV genotype associated with this fatal distemper infection in Gabon and compared it with other published CDV sequences...
March 2, 2018: Virus Research
https://www.readbyqxmd.com/read/29371956/canine-distemper-viral-infection-threatens-the-giant-panda-population-in-china
#15
Yipeng Jin, Xinke Zhang, Yisheng Ma, Yanchao Qiao, Xiaobin Liu, Kaihui Zhao, Chenglin Zhang, Degui Lin, Xuelian Fu, Xinrong Xu, Yiwei Wang, Huanan Wang
We evaluated exposure to canine distemper virus (CDV) in eight wild giant pandas ( Ailuropoda melanoleuca ) and 125 unvaccinated domestic dogs living in and around Foping National Nature Reserve (FNNR), China. Seventy-two percent of unvaccinated domestic dogs (mixed breed) had neutralizing antibodies for CDV due to exposure to the disease. The eight wild giant pandas were naïve to CDV and carried no positive antibody titer. RT-PCR assays for hemagglutinin ( H ) gene confirmed the presence of CDV in 31 clinically ill dogs from several areas near FNNR...
December 26, 2017: Oncotarget
https://www.readbyqxmd.com/read/29369728/introduction-and-establishment-of-raccoon-rabies-on-islands-jekyll-island-georgia-usa-as-a-case-study
#16
Sebastian Ortiz, Sonia M Hernandez, Michael J Yabsley, Trista I Becker, Benjamin Carswell, Yank Moore, Heather Fenton, Charlie S Bahnson, Kevin Niedringhaus, Elizabeth Elsmo, Lillian Orciari, Pamela Yager, Nancy L Stedman, Steven E Nelson, Terry M Norton
  The introduction of rabies virus (RABV) to barrier islands, which are often popular tourist destinations with resource-rich habitats and connectivity and proximity to the mainland, is especially concerning because it can easily become endemic due to factors like dense rabies-vector populations (e.g., raccoons [ Procyon lotor]), high inter- and intraspecies contact rates, and anthropogenic activities such as supplemental feeding of feral cats ( Felis catus). In January 2013, a neurologic raccoon found on the Jekyll Island (JI), Georgia, US causeway tested positive for rabies...
April 2018: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/29367517/one-step-triplex-pcr-rt-pcr-to-detect-canine-distemper-virus-canine-parvovirus-and-canine-kobuvirus
#17
Dafei Liu, Fei Liu, Dongchun Guo, Xiaoliang Hu, Zhijie Li, Zhigang Li, Jianzhang Ma, Chunguo Liu
To rapidly distinguish Canine distemper virus (CDV), canine parvovirus (CPV), and canine kobuvirus (CaKoV) in practice, a one-step multiplex PCR/RT-PCR assay was developed, with detection limits of 102.1 TCID50 for CDV, 101.9 TCID50 for CPV and 103 copies for CaKoV. This method did not amplify nonspecific DNA or RNA from other canine viruses. Therefore, the assay provides a sensitive tool for the rapid clinical detection and epidemiological surveillance of CDV, CPV and CaKoV in dogs.
January 23, 2018: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29351737/identifying-genome-wide-immune-gene-variation-underlying-infectious-disease-in-wildlife-populations-a-next-generation-sequencing-approach-in-the-gopher-tortoise
#18
Jean P Elbers, Mary B Brown, Sabrina S Taylor
BACKGROUND: Infectious disease is the single greatest threat to taxa such as amphibians (chytrid fungus), bats (white nose syndrome), Tasmanian devils (devil facial tumor disease), and black-footed ferrets (canine distemper virus, plague). Although understanding the genetic basis to disease susceptibility is important for the long-term persistence of these groups, most research has been limited to major-histocompatibility and Toll-like receptor genes. To better understand the genetic basis of infectious disease susceptibility in a species of conservation concern, we sequenced all known/predicted immune response genes (i...
January 19, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29316493/transmission-of-morbilliviruses-within-and-among-marine-mammal-species
#19
REVIEW
Wendy K Jo, Albert Dme Osterhaus, Martin Ludlow
Transmission of morbilliviruses within and among marine mammal species has been documented in a variety of marine habitats. Cetacean morbillivirus spreads between cetacean species in the aquatic environment whereas both phocine distemper virus and canine distemper virus have been associated with transmission within and between pinniped and terrestrial carnivore species in their natural habitat and at the aquatic-terrestrial interface. Periodically these viruses have caused large epizootics involving thousands of animals, due to sustained intra-species virus transmission...
February 2018: Current Opinion in Virology
https://www.readbyqxmd.com/read/29297815/serologic-response-to-canine-distemper-vaccination-in-captive-linnaeus-s-two-toed-sloths-choloepus-didactylus-after-a-fatal-canine-distemper-virus-outbreak
#20
Julie D Sheldon, Andrew C Cushing, Rebecca P Wilkes, Eman Anis, Edward J Dubovi
Canine distemper virus (CDV) affects many wild and captive, nondomestic species worldwide but has not been previously reported in Xenarthra. Paucity of information on vaccination safety and efficacy presents challenges for disease prevention in captive collections. CDV infections and subsequent mortalities in five captive Linnaeus's two-toed sloths ( Choloepus didactylus) in eastern Tennessee are reported. Clinical signs included oculonasal discharge, oral ulcerations, and diarrhea, and the diagnosis was confirmed by necropsy, histopathology, immunohistochemistry, virus isolation, and polymerase chain reaction...
December 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
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