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https://www.readbyqxmd.com/read/16026469/dopamine-d1-like-receptor-modulates-layer-and-frequency-specific-short-term-synaptic-plasticity-in-rat-prefrontal-cortical-neurons
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COMPARATIVE STUDY
Clint E Young, Charles R Yang
The mesocortical dopamine (DA) input to the prefrontal cortex (PFC) is crucial for processing short-term working memory (STWM) to guide forthcoming behavior. Short-term plasticity-like post-tetanic potentiation (PTP, < 3 min) and short-term potentiation (STP, < 10 min) may underlie STWM. Using whole-cell voltage-clamp recordings, mixed glutamatergic excitatory postsynaptic currents (EPSCs) evoked by layer III or layer V stimulation (0.5 or 0.067 Hz) were recorded from layer V pyramidal neurons. With 0...
June 2005: European Journal of Neuroscience
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