keyword
https://read.qxmd.com/read/38236137/rapid-initiation-of-antiretroviral-therapy-with-coformulated-bictegravir-emtricitabine-tenofovir-alafenamide-versus-efavirenz-lamivudine-and-tenofovir-disoproxil-fumarate-in-hiv-positive-men-who-have-sex-with-men-in-china-week-48-results-of-the-multicenter
#21
JOURNAL ARTICLE
Ran Wang, Lijun Sun, Xi Wang, Yuanyi Zhai, Lijing Wang, Ping Ma, Cuisong Wu, Yingquan Zhou, Renfang Chen, Rugang Wang, Fengchi Zhang, Wei Hua, Aixin Li, Wei Xia, Yue Gao, Rui Li, Shiyun Lv, Ying Shao, Yu Cao, Tong Zhang, Hao Wu, Chao Cai, Lili Dai
BACKGROUND: Most international treatment guidelines recommend rapid initiation of antiretroviral therapy (ART) for people newly diagnosed with HIV-1 infection, but experiences with rapid ART initiation remain limited in China. We aimed to evaluate the efficacy and safety of efavirenz (400-mg) plus lamivudine and tenofovir disoproxil fumarate (EFV + 3TC + TDF) versus coformulated bictegravir, emtricitabine, tenofovir alafenamide (BIC/FTC/TAF) in rapid ART initiation among HIV-positive men who have sex with men (MSM)...
January 17, 2024: Clinical Infectious Diseases
https://read.qxmd.com/read/38218782/the-impact-of-text-message-reminders-on-cryotherapy-uptake-among-women-testing-positive-for-hpv-in-western-kenya-a-prospective-cohort-study
#22
JOURNAL ARTICLE
Yujung Choi, Saduma Ibrahim, Lawrence P Park, Elizabeth A Bukusi, Megan J Huchko
BACKGROUND: Mobile health (mHealth) has become an increasingly popular strategy to improve healthcare delivery and health outcomes. Communicating results and health education via text may facilitate program planning and promote better engagement in care for women undergoing human papillomavirus (HPV) screening. We sought to develop and evaluate an mHealth strategy with enhanced text messaging to improve follow-up throughout the cervical cancer screening cascade. METHODS: Women aged 25-65 participated in HPV testing in six community health campaigns (CHCs) in western Kenya as part of a single arm of a cluster-randomized trial...
January 13, 2024: BMC Women's Health
https://read.qxmd.com/read/38216437/integrated-biobehavioral-surveillance-among-people-who-inject-drugs-in-ukraine-2007-2020
#23
JOURNAL ARTICLE
Kostyantyn Dumchev, Oksana Kovtun, Serhii Salnikov, Ivan Titar, Tetiana Saliuk
BACKGROUND: Repeated integrated biobehavioral surveys (IBBS) have been implemented among people who inject drugs (PWID) in Ukraine to monitor the trends in key epidemiologic and programmatic indicators. METHODS: The study analyzed seven PWID IBBS rounds from 2007 to 2020 in seven Ukrainian cities. Participants were recruited using respondent-driven sampling, tested for HIV and anti-HCV antibodies, and completed a structured questionnaire. Composite weights (based on individual sampling probability and population size) were applied to generate point estimates and confidence intervals for HIV and HCV prevalence, injection risk behaviors, prevention service coverage, and HIV treatment cascade...
January 11, 2024: International Journal on Drug Policy
https://read.qxmd.com/read/38211958/facility-based-indicators-to-manage-and-scale-up-cervical-cancer-prevention-and-care-services-for-women-living-with-hiv-in-sub-saharan-africa-a-three-round-online-delphi-consensus-method
#24
JOURNAL ARTICLE
Maša Davidović, Serra Lem Asangbeh, Katayoun Taghavi, Tafadzwa Dhokotera, Antoine Jaquet, Beverly Musick, Cari Van Schalkwyk, David Schwappach, Eliane Rohner, Gad Murenzi, Kara Wools-Kaloustian, Kathryn Anastos, Orang'o Elkanah Omenge, Simon Pierre Boni, Stephany N Duda, Per von Groote, Julia Bohlius
BACKGROUND: Of women with cervical cancer (CC) and HIV, 85% live in sub-Saharan Africa, where 21% of all CC cases are attributable to HIV infection. We aimed to generate internationally acceptable facility-based indicators to monitor and guide scale up of CC prevention and care services offered on-site or off-site by HIV clinics. METHODS: We reviewed the literature and extracted relevant indicators, grouping them into domains along the CC control continuum. From February 2021 to March 2022, we conducted a three-round, online Delphi process to reach consensus on indicators...
February 1, 2024: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://read.qxmd.com/read/38205796/hepatitis-b-care-continuum-models-data-to-inform-public-health-action
#25
REVIEW
Philip R Spradling, Angelica Bocour, Danica E Kuncio, Kathleen N Ly, Aaron M Harris, Nicola D Thompson
The application of a care continuum model (CCM) can identify gaps in diagnosis, care, and treatment of populations with a common condition, but challenges are inherent in developing a CCM for chronic hepatitis B. In contrast with treatment for HIV or hepatitis C, treatment is not indicated for all people with chronic hepatitis B, clinical endpoints are not clear for those receiving treatment, and those for whom treatment is not indicated remain at risk for complications. This topical review examines the data elements necessary to develop and apply chronic hepatitis B CCMs at the jurisdictional health department level...
January 11, 2024: Public Health Reports
https://read.qxmd.com/read/38200516/barriers-and-facilitators-to-improving-the-cascade-of-hiv-care-in-ontario-a-mixed-method-study
#26
JOURNAL ARTICLE
Lawrence Mbuagbaw, Saranee Fernando, Chloe Lee, Maureen Owino, Cynthia Youssef, M Elizabeth Snow
BACKGROUND: Engagement in care is important for people living with HIV (PLH) to achieve optimal outcomes. Several strategies have been developed to improve client flow through the HIV care cascade, specifically targeting initiation of treatment, adherence to antiretroviral therapy (ART), retention in care, and engagement in care. We have previously identified effective care cascade strategies in a systematic review. Initiation of ART could be improved by mobile health interventions, and changes in healthcare delivery...
January 10, 2024: BMC Health Services Research
https://read.qxmd.com/read/38168425/-this-is-an-illness-no-one-is-supposed-to-be-treated-badly-community-based-stigma-assessments-in-south-africa-to-inform-tb-stigma-intervention-design
#27
Isabel Foster, Amanda Biewer, Nosivuyile Vanqa, Goodman Makanda, Phumeza Tisile, Sally E Hayward, Dillon T Wademan, Michaile G Anthony, Rachel Mbuyamba, Michelle Galloway, Wieda Human, Helene-Mari Westhuizen, Jon S Friedland, Andrew Marino-Medina, Ingrid Schoeman, Graeme Hoddinott, Ruvandhi R Nathavitharana
Background Though TB-related stigma is a recognized barrier to care, interventions are lacking and gaps remain in understanding the drivers and experiences of TB-related stigma. We undertook community-based mixed methods stigma assessments to inform stigma intervention design. Methods We adapted the Stop TB Partnership stigma assessment tool, and trained three peer research associates (PRAs; two TB survivors, one community health worker) to conduct surveys with people with TB (PWTB, n=93) and caregivers of children with TB (n=24) at peri-urban and rural clinic sites in Khayelitsha, Western Cape, and Hammanskraal, Gauteng Province, South Africa...
December 11, 2023: Research Square
https://read.qxmd.com/read/38141149/an-online-hiv-self-sampling-strategy-for-gay-bisexual-and-other-men-who-have-sex-with-men-and-trans-women-in-spain
#28
JOURNAL ARTICLE
Héctor Martínez-Riveros, Yesika Díaz, Marcos Montoro-Fernandez, Sergio Moreno-Fornés, Victoria González, Esteve Muntada, Pol Romano-deGea, Rafael Muñoz, Juan Hoyos, Jordi Casabona, Cristina Agustí
We aimed to evaluate the feasibility of an online self-sampling pilot intervention for HIV testing addressed to gay, bisexual, and other men who have sex with men (GBMSM) and trans women (TW) users of dating apps in Spain. The website https://www.testate.org/ was designed to offer self-sampling kits for HIV testing and online consultation of the results. It was advertised on gay dating apps. Participants requested the delivery of a saliva self-sampling kit by mail and a postage-paid envelope to send the sample to the reference laboratory...
December 23, 2023: Journal of Community Health
https://read.qxmd.com/read/38140655/differences-in-hcv-seroprevalence-clinical-features-and-treatment-outcomes-between-female-and-male-incarcerated-population-results-from-a-matched-cohort-study
#29
JOURNAL ARTICLE
Vito Fiore, Andrea De Vito, Elena Rastrelli, Valentina Manca, Giuseppe De Matteis, Roberto Ranieri, Emanuele Pontali, Nicholas Geremia, Sandro Panese, Giulio Starnini, Giordano Madeddu, Sergio Babudieri
BACKGROUND: Women represent less than 5% of the incarcerated population in Italy, with very limited data on HCV infection. Higher HCV seroprevalence and active infection rates have been described among incarcerated females in available studies. Our aim is to compare the prevalence and cascade of care of HCV between male and female populations in Italian penitentiaries. METHODS: We conducted a multicentre, retrospective study comparing HCV seroprevalence, active infections, treatment, and SVR rates between female (Group A) and male (Group B) populations in Italian prison settings...
December 12, 2023: Viruses
https://read.qxmd.com/read/38133999/adolescents-and-young-adults-are-the-most-undiagnosed-of-hiv-and-virally-unsuppressed-in-eastern-and-southern-africa-pooled-analyses-from-five-population-based-surveys
#30
JOURNAL ARTICLE
Helena Huerga, Jihane Ben Farhat, David Maman, Nolwenn Conan, Gilles Van Cutsem, Willis Omwoyo, Daniela Garone, Reinaldo Ortuno Gutierrez, Tsitsi Apollo, Gordon Okomo, Jean-François Etard
Age and gender disparities within the HIV cascade of care are critical to focus interventions efficiently. We assessed gender-age groups at the highest probability of unfavorable outcomes in the HIV cascade in five HIV prevalent settings. We performed pooled data analyses from population-based surveys conducted in Kenya, South Africa, Malawi and Zimbabwe between 2012 and 2016. Individuals aged 15-59 years were eligible. Participants were tested for HIV and viral load was measured. The HIV cascade outcomes and the probability of being undiagnosed, untreated among those diagnosed, and virally unsuppressed (≥1,000 copies/mL) among those treated were assessed for several age-gender groups...
2023: PLOS Glob Public Health
https://read.qxmd.com/read/38129852/gaps-in-the-type-2-diabetes-care-cascade-a-national-perspective-using-south-africa-s-national-health-laboratory-service-nhls-database
#31
JOURNAL ARTICLE
Alana T Brennan, Evelyn Lauren, Jacob Bor, Jaya A George, Kamy Chetty, Koleka Mlisana, Andrew Dai, Siyabonga Khoza, Sydney Rosen, Andrew C Stokes, Frederick Raal, Patricia Hibberd, Sara M Alexanian, Matthew P Fox, Nigel J Crowther
BACKGROUND: Research out of South Africa estimates the total unmet need for care for those with type 2 diabetes mellitus (diabetes) at 80%. We evaluated the care cascade using South Africa's National Health Laboratory Service (NHLS) database and assessed if HIV infection impacts progression through its stages. METHODS: The cohort includes patients from government facilities with their first glycated hemoglobin A1c (HbA1c) or plasma glucose (fasting (FPG); random (RPG)) measured between January 2012 to March 2015 in the NHLS...
December 21, 2023: BMC Health Services Research
https://read.qxmd.com/read/38111520/evaluating-elimination-of-mother-to-child-transmission-of-hiv-in-suriname-a-mixed-method-study
#32
JOURNAL ARTICLE
Deborah Stijnberg, Suze Holband, Regillio Charles, Dorien Ulenaers, Ward Schrooten, Malti R Adhin
OBJECTIVES: To evaluate the cascade of care for the elimination of mother-to-child-transmission of human immunodeficiency virus (HIV) in Suriname and identify sociodemographic and clinical factors preventing transmission to exposed infants. METHODS: A mixed-methods study design was used. Antenatal care data from the 2018 cross-sectional multi-indicator cluster survey on 1 026 women aged 15-49 years who had had a live birth in the previous 2 years were used. Furthermore, national data on a cohort of 279 mothers with HIV and their 317 infants born from 2016 to 2018 were evaluated...
2023: Pan American Journal of Public Health
https://read.qxmd.com/read/38091300/hiv-treatment-cascade-among-female-sex-workers-in-ethiopia-assessment-against-the-unaids-90-90-90-targets
#33
JOURNAL ARTICLE
Saro Abdella, Meaza Demissie, Alemayehu Worku, Merga Dheresa, Yemane Berhane
BACKGROUND: HIV treatment cascades for HIV-positive female sex workers (FSWs) have been challenged by the overlapping stigma and discrimination associated with both their sex work and HIV status. This study aims to assess the proportion of HIV-positive FSWs who access care and treatment in Ethiopia. METHOD: A cross-sectional study with a respondent-driven sampling technique was used to enroll 6,085 female sex workers from January to June 2020. Interviews were conducted to assess the FSWs' HIV status awareness and access to ART...
2023: PloS One
https://read.qxmd.com/read/38049823/models-of-good-practice-to-enhance-infectious-disease-care-cascades-among-people-who-inject-drugs-a-qualitative-study-of-interventions-implemented-in-european-settings
#34
JOURNAL ARTICLE
Ilonka Horváth, Otilia Mårdh, Tanja Schwarz
BACKGROUND: People who inject drugs (PWID) in Europe are at an increased risk of HIV/AIDS, chronic viral hepatitis B (HBV) and C (HCV), and tuberculosis (TB). We aimed to complement the evidence base on interventions optimising their care cascade with evidence from models of good practice (MoGPs) implemented in the EU/EEA and countries from the Eastern European region. METHODS: A model of good practice (MoGP) was defined as (a package of) interventions with proven effectiveness in certain settings that are likely to be replicable and sustainable in other settings or countries...
December 4, 2023: BMC Health Services Research
https://read.qxmd.com/read/38045529/an-implementation-strategy-package-video-education-hiv-self-testing-and-co-location-improves-prep-implementation-for-pregnant-women-in-antenatal-care-clinics-in-western-kenya
#35
JOURNAL ARTICLE
Joseph Sila, Anjuli D Wagner, Felix Abuna, Julia C Dettinger, Ben Odhiambo, Nancy Ngumbau, George Oketch, Enock Sifuna, Laurén Gómez, Sarah Hicks, Grace John-Stewart, John Kinuthia
BACKGROUND: Pre-exposure prophylaxis (PrEP) is recommended by the World Health Organization and the Kenyan Ministry of Health for HIV prevention in pregnancy and postpartum for women at risk for HIV. Integration of PrEP into antenatal care is promising, but delivery gaps exist in the face of healthcare provider shortages in resource-limited settings. METHODS: Between May and November 2021, we conducted a difference-in-differences study (3 months pre-intervention data collection and 3 months post-intervention data collection) analyzing four intervention facilities, where the strategies were implemented, and four comparison facilities, where no strategies were implemented...
2023: Front Reprod Health
https://read.qxmd.com/read/38037051/nurse-patient-relationship-and-its-implications-for-retention-in-the-pmtct-of-hiv-programme-in-ghana-an-appreciative-inquiry
#36
JOURNAL ARTICLE
Susanna Aba Abraham, Sheila E Clow
BACKGROUND: Relationships established between nurses and midwives, and their patients have far-reaching implications; the most significant being their impact on the health-related outcomes of patients. These relationships are especially relevant in the Prevention of Mother-to-Child Transmission (PMTCT) of Human Immunodeficiency Virus (HIV) programme as women, diagnosed with HIV navigate the emotional and psychological effects of their diagnosis while carrying pregnancies. This study aimed to explore the relationships between nurses, midwives and mothers diagnosed with HIV and its impact on retention in the PMTCT Programme...
November 30, 2023: BMC Nursing
https://read.qxmd.com/read/38011347/pre-exposure-prophylaxis-care-continuum-for-hiv-risk-populations-an-umbrella-review-of-systematic-reviews-and-meta-analyses
#37
REVIEW
Guifang Jin, Haiyan Shi, Jun Du, Haiyun Guo, Guojing Yuan, Huayu Yang, Zhihui Zhu, Jianghui Zhang, Kexin Zhang, Xueqing Zhang, Xiaoyan Lu, Wenzhuo Xu, Sainan Wang, Jiahu Hao, Ying Sun, Puyu Su, Zhihua Zhang
Pre-exposure prophylaxis (PrEP) is an effective biomedical strategy for HIV prevention. This umbrella review is aimed at providing a comprehensive summary of the current status of each stage of the PrEP care cascade. A systematic literature search was conducted in PubMed, Embase, and Cochrane. Additionally, a Measurement Tool to Assess Systematic Reviews 2 (AMSTAR-2) tool and Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) checklist were used to evaluate their methodological and reporting quality, respectively...
December 2023: AIDS Patient Care and STDs
https://read.qxmd.com/read/38009461/investigating-rates-and-predictors-of-viral-blips-low-level-viraemia-and-virological-failure-in-the-australian-hiv-observational-database
#38
JOURNAL ARTICLE
Win Min Han, Jennifer Broom, Rohan Bopage, David J Templeton, Natalie Edmiston, Kathy Petoumenos
OBJECTIVES: Australia has made significant progress towards achieving the UNAIDS's 95-95-95 cascade targets including HIV viral suppression. To investigate the burden of HIV viraemia, we assessed viral blips, low-level viraemia (LLV) and virologic failure (VF) in an Australian cohort. METHODS: We studied the proportion of people with viral suppression, viral blips, LLV and VF in the Australian HIV observational database (AHOD) between 2010 and 2021. The association between blips or LLV, and VF was investigated using Cox regression, and predictors of viral blips and LLV were assessed using repeated-measured logistic regression...
January 2024: Tropical Medicine & International Health
https://read.qxmd.com/read/37996221/statistical-methods-applied-for-the-assessment-of-the-hiv-cascade-and-continuum-of-care-a-systematic-scoping-review
#39
JOURNAL ARTICLE
Aneth Vedastus Kalinjuma, Tracy Renée Glass, Honorati Masanja, Maja Weisser, Amina Suleiman Msengwa, Fiona Vanobberghen, Kennedy Otwombe
OBJECTIVES: This scoping review aims to identify and synthesise existing statistical methods used to assess the progress of HIV treatment programmes in terms of the HIV cascade and continuum of care among people living with HIV (PLHIV). DESIGN: Systematic scoping review. DATA SOURCES: Published articles were retrieved from PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL) Complete and Excerpta Medica dataBASE (EMBASE) databases between April and July 2022...
November 23, 2023: BMJ Open
https://read.qxmd.com/read/37955807/hiv-information-avoidance-hiv-stigma-and-medical-mistrust-among-black-sexual-minority-men-in-the-southern-united-states-associations-with-hiv-testing
#40
JOURNAL ARTICLE
Kay A Simon, Redd Driver, Taylor Rathus, Ayeisha Cole, Jolaade Kalinowski, Ryan J Watson, Lisa A Eaton
Uptake of HIV testing is a critical step in the HIV prevention and treatment care cascade. Barriers to HIV testing, however, remain and innovative research in this area is warranted to improve uptake of testing. As such, we investigated the role of HIV information avoidance - a novel construct potentially related to HIV testing. We analyzed this construct in relation to other factors known to impact HIV testing, namely HIV stigma and medical mistrust. Multiple linear regression analyses indicated that HIV information avoidance was negatively associated with HIV testing, while medical mistrust was positively associated with HIV testing...
November 13, 2023: AIDS and Behavior
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