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Cascade of HIV care

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https://www.readbyqxmd.com/read/28645888/hiv-strategic-information-in-non-european-union-countries-in-the-world-health-organization-european-region-capacity-development-needs
#1
Ivana Bozicevic, Senad Handanagic, Jurja Ivana Cakalo, Annemarie Rinder Stengaard, George Rutherford
BACKGROUND: Capacity building of the national HIV strategic information system is a core component of the response to the HIV epidemic as it enables understanding of the evolving nature of the epidemic, which is critical for program planning and identification of the gaps and deficiencies in HIV programs. OBJECTIVE: The study aims to describe the results of the assessment of the needs for further development of capacities in HIV strategic information systems in the non-European Union (EU) countries in the World Health Organization European Region (EUR)...
June 23, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28643242/what-influences-linkage-to-care-after-home-based-hiv-counseling-and-testing
#2
Reshma Naik, Wanga Zembe, Fatima Adigun, Elizabeth Jackson, Hanani Tabana, Debra Jackson, Frank Feeley, Tanya Doherty
To maximize the benefits of test and treat strategies that utilize community-based HIV testing, clients who test positive must link to care in a timely manner. However, linkage rates across the HIV treatment cascade are typically low and little is known about what might facilitate or hinder care-seeking behavior. This qualitative study was conducted within a home-based HIV counseling and testing (HBHCT) intervention in South Africa. In-depth interviews were conducted with 30 HBHCT clients who tested HIV positive to explore what influenced their care-seeking behavior...
June 22, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28622034/the-experiences-of-newly-diagnosed-men-who-have-sex-with-men-entering-the-hiv-care-cascade-in-lima-peru-2015-2016-a-qualitative-analysis-of-counselor-participant-text-message-exchanges
#3
Erik Bayona, Luis Menacho, Eddy R Segura, Gitau Mburu, Fernando Roman, Consuelo Tristan, Elizabeth Bromley, Robinson Cabello
Mobile phone technology (mHealth) is a promising tool that has been used to improve HIV care in high-risk populations worldwide. Understanding patient perspectives of newly diagnosed men who have sex with men (MSM) in Lima, Peru during linkage and engagement in the HIV care continuum can help close the gaps in care following initial HIV diagnosis and ensure retention in continuous care. From June 2015 to March 2016, as part of a randomized controlled trial, 40 MSM participants were linked to care with an mHealth intervention within 3 months of HIV diagnosis at Via Libre clinic...
June 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28618980/evaluating-the-care-cascade-after-antiretroviral-therapy-initiation-in-latin-america
#4
Marcelo J Wolff, Claudia P Cortes, Fernando A Mejìa, Denis Padgett, Pablo Belaunzarán-Zamudio, Beatriz Grinsztejn, Mark J Giganti, Catherine C McGowan, Peter F Rebeiro
Accelerating antiretroviral therapy (ART) administration, improving retention, and achieving viral suppression in low- and middle-income countries must be prioritized. We evaluated trends and disparities in these milestones in a large Latin American cohort. Adults starting ART (ARTstart) from 2003 to 2014 at Caribbean, Central, and South America network for HIV epidemiology sites were assessed for care cascade outcomes: CD4 cell count >200 cells/mm(3) at ARTstart; retention (≥1 visit at one year after ARTstart); viral suppression (≥1 HIV-1 RNA <200 copies/ml at one year after ARTstart)...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28610602/associations-of-criminal-justice-and-substance-use-treatment-involvement-with-hiv-hcv-testing-and-the-hiv-treatment-cascade-among-people-who-use-drugs-in-oakland-california
#5
Barrot H Lambdin, Alex H Kral, Megan Comfort, Andrea M Lopez, Jennifer Lorvick
BACKGROUND: People who smoke crack cocaine and people who inject drugs are at-risk for criminal justice involvement as well as HIV and HCV infection. Compared to criminal justice involvement, substance use treatment (SUT) can be cost-effective in reducing drug use and its associated health and social costs. We conducted a cross-sectional study of people who smoke crack cocaine and people who inject drugs to examine the association between incarceration, community supervision and substance use treatment with HIV/HCV testing, components of the HIV treatment cascade, social and physical vulnerability and risk behavior...
June 14, 2017: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/28610435/access-and-engagement-in-hiv-care-among-a-national-cohort-of-women-living-with-hiv-in-canada
#6
Nadine Kronfli, Ashley Lacombe-Duncan, Ying Wang, Alexandra de Pokomandy, Angela Kaida, Carmen Logie, Tracey Conway, V Logan Kennedy, Ann Burchell, Wangari Tharao, Neora Pick, Mary Kestler, Paul Sereda, Mona Loutfy, On Behalf Of The Chiwos Research Team
Attrition along the cascade of HIV care poses significant barriers to attaining the UNAIDS targets of 90-90-90 and achieving optimal treatment outcomes for people living with HIV. Understanding the correlates of attrition is critical and particularly for women living with HIV (WLWH) as gender disparities along the cascade have been found. We measured the proportion of the 1425 WLWH enrolled in the Canadian HIV Women's Sexual and Reproductive Health Cohort Study (CHIWOS) who had never accessed HIV medical care, who reported delayed linkage into HIV care (>3 months between diagnosis and initial care linkage), and who were not engaged in HIV care at interview (<1 visit in prior year)...
June 13, 2017: AIDS Care
https://www.readbyqxmd.com/read/28606085/care-cascade-structural-intervention-versus-standard-of-care-in-the-diagnosis-and-treatment-of-hiv-in-china-a-cluster-randomized-controlled-trial-protocol
#7
Yurong Mao, Zunyou Wu, Jennifer M McGoogan, David Liu, Diane Gu, Lynda Erinoff, Walter Ling, Paul VanVeldhuisen, Roger Detels, Albert L Hasson, Robert Lindblad, Julio S G Montaner, Zhenzhu Tang, Yan Zhao
BACKGROUND: The high rate of attrition along the care cascade of infection with human immunodeficiency virus (HIV) results in lost opportunities to provide timely antiretroviral therapy (ART) and to prevent unnecessarily high mortality. This study aims to assess the effectiveness of a structural intervention, the one-stop ("One4All") strategy that streamlines China's HIV care cascade with the intent to improve testing completeness, ART initiation, viral suppression, and mortality. METHOD: A two-arm, cluster-randomized controlled trial was implemented in twelve county hospitals in Guangxi China to test the effectiveness of the One4All strategy (intervention arm) compared to the current standard of care (SOC; control arm)...
June 12, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28605228/sexual-assault-and-hiv-postexposure-prophylaxis-at-an-urban-african-hospital
#8
Eric Munene Muriuki, Joshua Kimani, Zipporah Machuki, James Kiarie, Alison C Roxby
Antiretroviral postexposure prophylaxis (PEP) may be underutilized in sexual assault cases in Kenya. This study evaluated the characteristics of survivors of sexual violence attending the Gender-Based Violence Recovery Center (GBVRC) at the Kenyatta National Hospital and reviewed the uptake, adherence, and outcomes of those initiated on PEP. In a retrospective cohort, data from charts of the assaulted seen at the GBVRC from 2009 to 2012 were abstracted. Data were collected describing sociodemographic characteristics, nature of sexual assault, HIV serostatus, and aspects of the PEP care cascade...
June 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28605171/human-immunodeficiency-virus-care-cascade-among-sub-populations-in-rakai-uganda-an-observational-study
#9
Veena G Billioux, Larry W Chang, Steven J Reynolds, Gertrude Nakigozi, Joseph Ssekasanvu, Mary K Grabowski, Robert Ssekubugu, Fred Nalugoda, Godfrey Kigozi, Joseph Kagaayi, David Serwadda, Ronald H Gray, Maria J Wawer
INTRODUCTION: To assess progress towards the UNAIDS 90-90-90 initiative targets, we examined the HIV care cascade in the population-based Rakai Community Cohort Study (RCCS) in rural Uganda and examined differences between sub-groups. METHODS: Self-reports and clinical records were used to assess the proportion achieving each stage in the cascade. Statistical inference based on a χ(2) test for categorical variables and modified Poisson regression were used to estimate prevalence risk ratios (PRRs) and 95% confidence intervals (CI) for enrolment into care and initiating antiretroviral therapy (ART)...
June 5, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28588933/can-the-unaids-90-90-90-target-be-achieved-a-systematic-analysis-of-national-hiv-treatment-cascades
#10
Jacob Levi, Alice Raymond, Anton Pozniak, Pietro Vernazza, Philipp Kohler, Andrew Hill
BACKGROUND: In 2014, the Joint United Nations Programme on HIV and AIDS (UNAIDS) and partners set the '90-90-90 targets'; aiming to diagnose 90% of all HIV positive people, provide antiretroviral therapy (ART) for 90% of those diagnosed and achieve viral suppression for 90% of those treated, by 2020. This results in 81% of all HIV positive people on treatment and 73% of all HIV positive people achieving viral suppression. We aimed to analyse how effective national HIV treatment programmes are at meeting these targets, using HIV care continuums or cascades...
August 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28574336/early-infant-diagnosis-of-hiv-in-myanmar-call-for-innovative-interventions-to-improve-uptake-and-reduce-turnaround-time
#11
Soe Thiha, Hemant Deepak Shewade, Sairu Philip, Thet Ko Aung, Nang Thu Thu Kyaw, Myo Minn Oo, Khine Wut Yee Kyaw, May Wint War, Htun Nyunt Oo
BACKGROUND: In collaboration with the national AIDS program, early infant diagnosis (EID) is implemented by Integrated HIV Care (IHC) program through its anti-retroviral therapy (ART) centers across 10 cities in five states and regions of Myanmar. Blood samples from the ART centers are sent using public transport to a centralized PCR facility. OBJECTIVES: Among HIV-exposed babies <9 months at enrolment into IHC program (2013-15), to describe the EID cascade (enrolment, sample collection for PCR, result receipt by mother, HIV diagnosis and ART initiation) and factors associated with delayed (>8 weeks of age) or no blood sample collection for EID...
2017: Global Health Action
https://www.readbyqxmd.com/read/28533167/performance-of-the-antiretroviral-treatment-program-in-ethiopia-2005-2015-strengths-and-weaknesses-toward-ending-aids
#12
Yibeltal Assefa, Charles F Gilks, Lutgarde Lynen, Owain Williams, Peter S Hill, Taye Tolera, Alankar Malvia, Wim Van Damme
BACKGROUND: Ethiopia is one of the countries which has scaled up antiretroviral treatment (ART) over the past decade. This study reviews the performance of the ART program in Ethiopia during the past decade, and identifies successes and weaknesses toward ending AIDS in the country. METHODS: A review and synthesis of data was conducted using multiple data sources: reports from all health facilities in Ethiopia to the Federal Ministry of Health, HIV/AIDS estimates and projections, and retrospective cohort and cross-sectional studies conducted between 2005/6 and 2014/15...
May 19, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28520807/time-from-hiv-diagnosis-to-commencement-of-antiretroviral-therapy-as-an-indicator-to-supplement-the-hiv-cascade-dramatic-fall-from-2011-to-2015
#13
Nicholas A Medland, Eric P F Chow, James H McMahon, Julian H Elliott, Jennifer F Hoy, Christopher K Fairley
INTRODUCTION: The HIV care cascade is increasingly used to evaluate HIV treatment programs at the population level. However, the cascade indicators lack the ability to show changes over time, which reduces their utility to guide health policy. Alternatives have been proposed but are complex or result in a delay in results. We propose a new indicator of ART uptake, the time from HIV diagnosis to commencement of ART, and compare it to the existing cascade indicator of proportion of patients on treatment and the WHO proposed cohort cascade indicator of proportion of patients on treatment within one year of diagnosis...
2017: PloS One
https://www.readbyqxmd.com/read/28511680/cohort-profile-seek-test-treat-and-retain-united-states-criminal-justice-cohort
#14
Redonna Chandler, Michael S Gordon, Bridget Kruszka, Lauren N Strand, Frederick L Altice, Curt G Beckwith, Mary L Biggs, William Cunningham, J A Chris Delaney, Patrick M Flynn, Carol E Golin, Kevin Knight, Alex H Kral, Irene Kuo, Jennifer Lorvick, Robin M Nance, Lawrence J Ouellet, Josiah D Rich, Stanley Sacks, David Seal, Anne Spaulding, Sandra A Springer, Faye Taxman, David Wohl, Jeremy D Young, Rebekah Young, Heidi M Crane
BACKGROUND: The STTR treatment cascade provides a framework for research aimed at improving the delivery of services, care and outcomes of PLWH. The development of effective approaches to increase HIV diagnoses and engage PLWH in subsequent steps of the treatment cascade could lead to earlier and sustained ART treatment resulting in viral suppression. There is an unmet need for research applying the treatment cascade to improve outcomes for those with criminal justice involvement. METHODS: The Seek, Test, Treat, and Retain (STTR) criminal justice (CJ) cohort combines data from 11 studies across the HIV treatment cascade that focused on persons involved in the criminal justice system, often but not exclusively for reasons related to substance use...
May 16, 2017: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/28498188/the-impact-of-structured-mentor-mother-programs-on-presentation-for-early-infant-diagnosis-testing-in-rural-north-central-nigeria-a-prospective-paired-cohort-study
#15
Nadia A Sam-Agudu, Habib O Ramadhani, Christopher Isah, Salome Erekaha, Chinenye Fan-Osuala, Udochisom Anaba, Ebunoluwa A Adejuyigbe, Manhattan Charurat
BACKGROUND: Early infant diagnosis (EID) by 2 months of age is an important prevention of mother-to-child cascade step that serves as an early postpartum indicator of program success. Uptake and timely presentation for infant HIV diagnosis are significant challenges in resource-limited settings. Few studies on maternal peer support (PS) have demonstrated impact on EID. The MoMent study evaluated the impact of structured PS on timely presentation for EID testing in rural North-Central Nigeria...
June 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28471841/a-flow-based-model-of-the-hiv-care-continuum-in-the-united-states
#16
Gregg S Gonsalves, A David Paltiel, Paul D Cleary, Michael John Gill, Mari M Kitahata, Peter F Rebeiro, Michael J Silverberg, Michael Horberg, Alison G Abraham, Keri N Althoff, Richard Moore, Ronald J Bosch, H Irene Hall, Edward H Kaplan
BACKGROUND: Understanding the flow of patients through the continuum of HIV care is critical to determine how best to intervene so that the proportion of HIV-infected persons who are on antiretroviral treatment and virally suppressed is as large as possible. METHODS: Using immunological and virological data from the Centers for Disease Control and Prevention and the North American AIDS Cohort Collaboration on Research and Design from 2009-2012, we estimated the distribution of time spent in and dropout probability from each stage in the continuum of HIV care...
April 26, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28465650/exploratory-analysis-of-time-from-hiv-diagnosis-to-art-start-factors-and-effect-on-survival-a-longitudinal-follow-up-study-at-seven-teaching-hospitals-in-ethiopia
#17
Alula M Teklu, Kesetebirhan Delele, Mulu Abraha, Bekele Belayhun, Esayas Kebede Gudina, Abiy Nega
BACKGROUND: The HIV care in Ethiopia has reached 79% coverage. The timeliness of the care provided at the different levels in the course of the disease starting from knowing HIV positive status to ART initiation is not well known. This study intends to explore the timing of the care seeking, the care provision and associated factors. METHODS: This is a longitudinal follow-up study at seven university hospitals. Patients enrolled in HIV care from September 2005 to December 2013 and aged ≥14 years were studied...
February 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/28459881/facilitators-and-barriers-for-retention-in-hiv-care-between-testing-and-treatment-in-asia-a-study-in-bangladesh-indonesia-lao-nepal-pakistan-philippines-and-vietnam
#18
Sushil Koirala, Keshab Deuba, Oranuch Nampaisan, Gaetano Marrone, Anna Mia Ekström
INTRODUCTION: The need for efficient retention in HIV care is more evident than ever because of the expansion of earlier ART initiation and the shift towards 'Test and Treat'. This study assesses factors affecting participation in the HIV care cascade among people living with HIV (PLHIV) in the Asia-Pacific Region. METHODS: A total of 7843 PLHIV aged 18-50 years were recruited using targeted and venue-based sampling between October 1, 2012, and May 31, 2013, across 59 sites in 7 countries (Bangladesh, Indonesia, Lao People's Democratic Republic (Lao PDR), Nepal, Pakistan, Philippines and Vietnam)...
2017: PloS One
https://www.readbyqxmd.com/read/28441975/seek-test-treat-substance-using-women-in-the-hiv-treatment-cascade-in-south-africa
#19
Wendee M Wechsberg, Charles van der Horst, Jacqueline Ndirangu, Irene A Doherty, Tracy Kline, Felicia A Browne, Jennifer M Belus, Robin Nance, William A Zule
BACKGROUND: Women in South Africa who use alcohol and other drugs face multiple barriers to HIV care. These barriers make it difficult for women to progress through each step in the HIV treatment cascade from diagnosis to treatment initiation and adherence. This paper examines correlates of HIV status, newly diagnosed HIV status, and use of antiretroviral therapy (ART). METHODS: Outreach workers recruited sexually active Black African women who used substances in Pretoria as part of a U...
April 26, 2017: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/28440604/a-proposed-novel-framework-for-monitoring-and-evaluation-of-the-cascade-of-hiv-associated-tb-care-at-the-health-facility-level
#20
Colleen F Hanrahan, Annelies Van Rie
INTRODUCTION: The rapid and accurate diagnosis of HIV-associated tuberculosis (TB), timely initiation of curative or preventative treatment and assurance of favourable treatment outcomes is a complex process. The current system of monitoring and reporting TB diagnosis and treatment does not include several key aspects of the care cascade, and may obscure systematic bottlenecks, inefficiencies or sources of sub-optimal care. METHODS: We critically reviewed the current World Health Organizations recommended system of monitoring and reporting, and identified the following key deficiencies that could limit the ability of healthcare workers to identify structural problems in the provision of TB/HIV care...
April 20, 2017: Journal of the International AIDS Society
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