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Cascade of HIV care

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https://www.readbyqxmd.com/read/28325068/the-relationship-between-health-worker-stigma-and-uptake-of-hiv-counseling-and-testing-and-utilization-of-non-hiv-health-services-the-experience-of-male-and-female-sex-workers-in-kenya
#1
Laura Nyblade, Aditi Reddy, David Mbote, John Kraemer, Melissa Stockton, Caroline Kemunto, Karol Krotki, Javier Morla, Stella Njuguna, Arin Dutta, Catherine Barker
The barrier HIV-stigma presents to the HIV treatment cascade is increasingly documented; however less is known about female and male sex worker engagement in and the influence of sex-work stigma on the HIV care continuum. While stigma occurs in all spheres of life, stigma within health services may be particularly detrimental to health seeking behaviors. Therefore, we present levels of sex-work stigma from healthcare workers (HCW) among male and female sex workers in Kenya, and explore the relationship between sex-work stigma and HIV counseling and testing...
March 22, 2017: AIDS Care
https://www.readbyqxmd.com/read/28319197/the-hiv-care-cascade-japanese-perspectives
#2
Aikichi Iwamoto, Rikizo Taira, Yoshiyuki Yokomaku, Tomohiko Koibuchi, Mahbubur Rahman, Yoko Izumi, Kenji Tadokoro
Japan has been known as a low HIV-prevalence country with a concentrated epidemic among high-risk groups. However, it has not been determined whether Japan meets the 90-90-90 goals set by the Joint United Nations Programme on HIV/AIDS (UNAIDS)/World Health Organization (WHO). Moreover, to date, the HIV care cascade has not been examined. We estimated the total number of diagnosed people living with HIV/AIDS (PLWHA) (n = 22,840) based on legal reports to the Ministry of Health, Labour and Welfare by subtracting the number of foreigners who left Japan (n = 2,273) and deaths (n = 2,321) from the cumulative diagnosis report (n = 27,434)...
2017: PloS One
https://www.readbyqxmd.com/read/28290773/the-hiv-care-cascade-and-sub-analysis-of-those-linked-to-but-not-retained-in-care-the-experience-from-a-tertiary-hiv-referral-service-in-dublin-ireland
#3
P McGettrick, B Ghavami-Kia, W Tinago, A Macken, J O'Halloran, J S Lambert, G Sheehan, P W G Mallon
BACKGROUND: The HIV Care Cascade model can be used to measure how clinical services align with United Nations' (UN) HIV treatment targets. Previous models have highlighted sequential losses at each step of the Cascade with a significant proportion being not retained in care (NRIC). OBJECTIVE: We aimed to assess the feasibility of meeting the UN targets and assess factors associated with, and calculate the true proportion of those, NRIC. METHODS: All people living with HIV who were linked to our service, one of three specialist HIV care providers in Dublin Ireland, from its establishment in 1993 to 1 December 2014, were included in the cohort and were categorized as linked to care, retained in care (RIC), on antiretroviral therapy (on ART), virally suppressed (HIV RNA <40copies/ml), and NRIC...
March 14, 2017: HIV Clinical Trials
https://www.readbyqxmd.com/read/28286006/it-s-not-just-the-pills-a-qualitative-meta-synthesis-of-hiv-antiretroviral-adherence-research
#4
Julie Barroso, Natalie M Leblanc, Dalmacio Flores
Antiretroviral therapy (ART) improves the health and longevity of people living with HIV infection (PLWH) and also prevents transmission of the virus. Yet, lack of adherence to ART regimens has been a persistent problem, even with simpler regimens. Guidelines that deal with ART adherence are based almost solely on quantitative studies; this focus ignores the context and complexity of patients' lives. Guidelines are also focused on the individual. We argue that the solution is to include the broader communities in which patients live, and to deal with systemic disparities that persist worldwide; this can be done in part through demedicalizing HIV care for healthy PLWH...
February 22, 2017: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/28278570/population-movements-and-the-hiv-cascade-in-recently-diagnosed-patients-at-the-french-guiana-suriname-border
#5
Raphael Jaries, Vincent Vantilcke, Philippe Clevenbergh, Jocelyne Adoissi, Rachida Boukhari, Caroline Misslin, Mathieu Nacher, Stephen Vreden, Anne Jolivet
Border areas are particular "hot spots" generating high levels of HIV vulnerability and facing great challenges to control epidemics. The objective of this study is to describe the sociodemographic, clinical and biological profiles of newly HIV diagnosed people at the French Guiana - Suriname border, to construct an HIV care cascade and compare it with the Surinamese one. HIV-patients aged over 15 years newly diagnosed in western French Guiana in 2011 and 2012 were included in a retrospective cohort study. Patients were identified using different sources (n = 121)...
February 13, 2017: AIDS Care
https://www.readbyqxmd.com/read/28270252/differences-between-migrants-and-spanish-born-population-through-the-hiv-care-cascade-catalonia-an-analysis-using-multiple-data-sources
#6
J Reyes-Urueña, C Campbell, C Hernando, N Vives, C Folch, L Ferrer, L Fernández-López, A Esteve, J Casabona
Migrants are considered a key group at risk for HIV infection. This study describes differences between migrants and the Spanish-born population as they progress through the HIV care cascade in Catalonia, Spain. This study found that among people reached by prevention activities, migrants had a higher number of barriers to access HIV testing services than Spanish-born people, driven primarily by shared risk factors. Between 2001 and 2013, 9829 new HIV diagnoses were reported in Catalonia, the proportion of migrants increasing from 24% in 2001 to 41% in 2013...
March 8, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28187084/uptake-of-hiv-pre-exposure-prophylaxis-prep-in-a-national-cohort-of-gay-and-bisexual-men-in-the-united-states
#7
Jeffrey T Parsons, H Jonathon Rendina, Jonathan M Lassiter, Thomas H F Whitfield, Tyrel J Starks, Christian Grov
OBJECTIVES: The HIV care cascade provides milestones to track the progress of HIV-positive people from seroconversion through viral suppression. We propose a Motivational pre-exposure prophylaxis (PrEP) Cascade involving 5 stages based on the Transtheoretical Model of Change. METHODS: We analyzed data from 995 men in One Thousand Strong, a longitudinal study of a national panel of HIV-negative gay and bisexual men in the United States. RESULTS: Nearly all (89%) participants were sexually active in the past 3 months and 65% met Centers for Disease Control criteria for PrEP candidacy...
March 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28158952/a-qualitative-study-of-thai-hiv-positive-young-men-who-have-sex-with-men-and-transgender-women-demonstrates-the-need-for-ehealth-interventions-to-optimize-the-hiv-care-continuum
#8
Tarandeep Anand, Chattiya Nitpolprasert, Stephen J Kerr, Kathryn E Muessig, Sangusa Promthong, Nitiya Chomchey, Lisa B Hightow-Weidman, Prachya Chaiyahong, Praphan Phanuphak, Jintanat Ananworanich, Nittaya Phanuphak
In Thailand, young men who have sex with men (YMSM) and transgender women (TG) are disproportionately affected by HIV and have suboptimal care continuum outcomes. Although Thai YMSM and young TG are early adopters of emerging technologies and have high Internet and technology access and utilization, the potential of technology has not been harnessed to optimize the HIV treatment cascade. We interviewed 18 behaviorally HIV-infected YMSM and young TG regarding care challenges, identified how eHealth could address care needs, and elicited preferences for eHealth interventions...
February 3, 2017: AIDS Care
https://www.readbyqxmd.com/read/28153470/from-hiv-infection-to-therapeutic-response-a-population-based-longitudinal-hiv-cascade-of-care-study-in-kwazulu-natal-south-africa
#9
Noah Haber, Frank Tanser, Jacob Bor, Kevindra Naidu, Tinofa Mutevedzi, Kobus Herbst, Kholoud Porter, Deenan Pillay, Till Bärnighausen
BACKGROUND: Standard approaches to estimation of losses in the HIV cascade of care are typically cross-sectional and do not include the population stages before linkage to clinical care. We used indiviual-level longitudinal cascade data, transition by transition, including population stages, both to identify the health-system losses in the cascade and to show the differences in inference between standard methods and the longitudinal approach. METHODS: We used non-parametric survival analysis to estimate a longitudinal HIV care cascade for a large population of people with HIV residing in rural KwaZulu-Natal, South Africa...
January 30, 2017: Lancet HIV
https://www.readbyqxmd.com/read/28134713/hiv-viral-load-scale-up-multiple-interventions-to-meet-the-hiv-treatment-cascade
#10
Sergio Carmona, Trevor Peter, Leigh Berrie
PURPOSE OF REVIEW: In 2015, the WHO urged countries to provide ART to all people living with HIV, irrespective of their CD4 cell count, this new recommendation supports the Joint United Nations Programme on HIV/AIDS elimination targets. However, to meet these aims, urgent scale-up of viral load testing is critical. The multiple interventions in the healthcare system required to support scale-up of viral load testing are reviewed here. RECENT FINDINGS: It is estimated that 18...
March 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28134712/diagnosis-and-monitoring-of-hiv-programmes-to-support-treatment-initiation-and-follow-up-and-improve-programme-quality
#11
Willem Daniel Francois Venter, Nathan Ford, Marco Vitoria, Wendy Stevens
PURPOSE OF REVIEW: The HIV 'cascade of care' breaks down at several points, with delayed HIV diagnosis, late treatment initiation, or interruption, leading to new morbidity and mortality and loss of prevention effects. New approaches are needed at each step. RECENT FINDINGS: HIV testing is still not reaching certain communities, resulting in late presentation. Creative ways to reach these communities is being explored, including with self-testing. HIV misdiagnosis is increasingly recognized as undermining testing programmes, highlighting the need for better quality control...
March 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28102027/patient-engagement-in-hiv-care-and-treatment-in-zambia-2004-2014
#12
Neo Christopher Chung, Carolyn Bolton-Moore, Roma Chilengi, Margaret P Kasaro, Jeffrey S A Stringer, Benjamin H Chi
OBJECTIVE: To describe engagement along the HIV continuum of care using a large network of clinics in Zambia. METHODS: We employed a practical framework to describe retention along the HIV treatment cascade, using routinely collected clinical data available in resource-constrained settings. We included health facilities in four Zambian provinces with more than 300 enrolled patients over the age of 5 years. We described attrition at each step, from HIV enrolment to 720 days after ART initiation...
January 19, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28095904/evaluation-of-the-tsima-community-mobilization-intervention-to-improve-engagement-in-hiv-testing-and-care-in-south-africa-study-protocol-for-a-cluster-randomized-trial
#13
Sheri A Lippman, Audrey Pettifor, Dumisani Rebombo, Aimée Julien, Ryan G Wagner, Mi-Suk Kang Dufour, Chodziwadziwa Whiteson Kabudula, Torsten B Neilands, Rhian Twine, Ann Gottert, F Xavier Gómez-Olivé, Stephen M Tollman, Ian Sanne, Dean Peacock, Kathleen Kahn
BACKGROUND: HIV transmission can be decreased substantially by reducing the burden of undiagnosed HIV infection and expanding early and consistent use of antiretroviral therapy (ART). Treatment as prevention (TasP) has been proposed as key to ending the HIV epidemic. To activate TasP in high prevalence countries, like South Africa, communities must be motivated to know their status, engage in care, and remain in care. Community mobilization (CM) has the potential to significantly increase uptake testing, linkage to and retention in care by addressing the primary social barriers to engagement with HIV care-including poor understanding of HIV care; fear and stigma associated with infection, clinic attendance and disclosure; lack of social support; and gender norms that deter men from accessing care...
January 17, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28070923/the-cascade-of-hiv-care-among-refugees-and-nationals-in-nakivale-refugee-settlement-in-uganda
#14
K N O'Laughlin, J Kasozi, D J Rabideau, R A Parker, E Mulogo, Z M Faustin, K E Greenwald, S Doraiswamy, R P Walensky, I V Bassett
OBJECTIVES: Refugees living in Uganda come from HIV-endemic countries, and many remain in refugee settlements for over a decade. Our objective was to evaluate the HIV care cascade in Nakivale Refugee Settlement and to assess correlates of linkage to care. METHODS: We prospectively enrolled individuals accessing clinic-based HIV testing in Nakivale Refugee Settlement from March 2013 to July 2014. Newly HIV-diagnosed clients were followed for 3 months post-diagnosis...
January 10, 2017: HIV Medicine
https://www.readbyqxmd.com/read/28055823/mental-health-in-2020-for-men-who-have-sex-with-men-in-the-united-states
#15
Abigail W Batchelder, Steven Safren, Avery D Mitchell, Ivan Ivardic, Conall O'Cleirigh
Despite continued advances in HIV prevention and treatment, gay and bisexual men and other men who have sex with men (MSM) remain the population most impacted by HIV/AIDS in the US and many other Western countries. Additionally, MSM are disproportionately affected by various psychological problems, including depression, distress, trauma and substance use. These challenges frequently co-occur, and are associated with higher rates of behaviours related to HIV acquisition and transmission, HIV infection, and, for those living with HIV/AIDS, lower levels of treatment engagement...
January 6, 2017: Sexual Health
https://www.readbyqxmd.com/read/28051324/progress-towards-achieving-the-unaids-90-90-90-goals-in-hiv-care-from-diagnosis-to-durable-viral-suppression-in-the-country-of-georgia
#16
Nikoloz Chkhartishvili, Otar Chokoshvili, Akaki Abutidze, Natia Dvali, Carlos Del Rio, Tengiz Tsertsvadze
Successful engagement in HIV care is required to reach UNAIDS targets of 90-90-90. We analyzed routine programmatic data to quantify losses along the HIV care continuum in the country of Georgia. Analysis was limited to diagnosed persons and did not include estimated number of HIV infected persons. Cascade of HIV care continuum was constructed for adult (age≥18 years) HIV-infected persons newly diagnosed in Georgia in 2008-2012. Data was extracted from the national AIDS Health Information System as of June 30, 2014...
January 4, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/27984917/the-south-carolina-rural-urban-hiv-continuum-of-care
#17
Babatunde Edun, Medha Iyer, Helmut Albrecht, Sharon Weissman
The HIV continuum of care model is widely used by various agencies to describe the HIV epidemic in stages from diagnosis through to virologic suppression. It identifies the various points at which persons living with HIV (PLWHIV) within a population fail to reach their next step in HIV care. The rural population in the Southern United States is disproportionally affected by the HIV epidemic. The purpose of this study was to examine these rural-urban disparities using the HIV care continuum model and determine at what stages these differences become apparent...
December 16, 2016: AIDS Care
https://www.readbyqxmd.com/read/27968864/hiv-testing-campaigns-and-treatment-interventions-for-control-of-epidemic-hiv-growth-among-heterosexuals-a-mathematical-modelling-study
#18
Ngai Sze Wong, Ka Hing Wong, Owen T Y Tsang, Man Po Lee, Shui Shan Lee
BACKGROUND: In 2015, WHO recommended universal antiretroviral treatment for HIV irrespective of CD4 cell count. The impact of this recommendation on heterosexual HIV transmission, especially in low prevalence countries, has not been well-characterised. In Hong Kong, 38% of reported HIV cases are heterosexually acquired. We aimed to model the impacts of enhanced HIV testing and immediate treatment to provide a reference to other provinces in China. METHODS: We developed deterministic compartmental models (sexually active heterosexual males and females) for simulation of HIV epidemiology for 1983-2011 in Hong Kong, with data projected to 2012-20...
October 2016: Lancet
https://www.readbyqxmd.com/read/27956646/engagement-in-and-continuity-of-hiv-care-among-african-and-caribbean-black-women-living-with-hiv-in-ontario-canada
#19
Carmen H Logie, Victoria L Kennedy, Wangari Tharao, Uzma Ahmed, Mona R Loutfy
Engagement in care is a key component of the HIV care cascade, yet there are knowledge gaps regarding how to assess HIV care engagement. This study aimed to develop a tool to assess HIV care engagement and to assess associations between HIV care engagement and quality of life (QOL) among African, Caribbean and Black (ACB) women living with HIV (WLWH). We conducted a cross-sectional survey with ACB WLWH across Ontario, Canada. We developed the 'HIV Engagement in and Continuity of Care Scale' (HECCS). We conducted exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) to test the scale's factor structure...
December 12, 2016: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/27930599/the-hiv-care-cascade-among-female-sex-workers-in-zimbabwe-results-of-a-population-based-survey-from-the-sisters-antiretroviral-therapy-programme-for-prevention-of-hiv-an-integrated-response-sapph-ire-trial
#20
Frances M Cowan, Calum Davey, Elizabeth Fearon, Phillis Mushati, Jeffrey Dirawo, Valentina Cambiano, Sue Napierala Mavedzenge, Dagmar Hanisch, Ramona Wong-Gruenwald, Milton Chemhuru, Nyasha Masuka, Karin Hatzold, Owen Mugurungi, Joanna Busza, Andrew Phillips, James R Hargreaves
INTRODUCTION: Female sex workers (FSW) in sub-Saharan Africa have a higher prevalence of HIV than other women of reproductive age. Social, legal, and structural barriers influence their access to care. Little is known about the HIV diagnosis and care cascade in most countries in southern Africa. We aimed to describe the HIV diagnosis and care cascade among FSW in Zimbabwe. METHODS: We conducted cross-sectional respondent driven sampling (RDS) surveys of FSW in 14 sites across Zimbabwe as the baseline for a cluster-randomised controlled trial investigating a combination HIV prevention and care package...
December 1, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
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