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Cascade of HIV care

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https://www.readbyqxmd.com/read/29676000/the-2016-hiv-diagnosis-and-care-cascade-in-new-south-wales-australia-meeting-the-unaids-90-90-90-targets
#1
Phillip Keen, Richard T Gray, Barbara Telfer, Rebecca Guy, Heather-Marie Schmidt, Bill Whittaker, Jo Holden, Martin Holt, Anthony Kelleher, David Wilson, Denton Callander, David A Cooper, Garrett Prestage, Christine Selvey, Andrew E Grulich
INTRODUCTION: The HIV Strategy in New South Wales (NSW) Australia aims to virtually eliminate HIV transmission by 2020. We estimated the 2016 HIV diagnosis and care cascade for the state of NSW, with a focus on introducing population-based data to improve data quality and assess progress towards the UNAIDS 90-90-90 targets. METHODS: To estimate the number of people living with diagnosed HIV (PLDHIV) we used NSW data from the Australian National HIV Registry, enhanced by surveillance among people recently diagnosed with HIV to improve migration estimates...
April 2018: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29602851/patient-perspectives-on-the-hiv-continuum-of-care-in-london-a-qualitative-study-of-people-diagnosed-between-1986-and-2014
#2
Jane Bruton, Tanvi Rai, Sophie Day, Helen Ward
OBJECTIVES: To describe the experiences of the HIV treatment cascade of diagnosis, engagement with care and initiation of treatment from the perspective of patients; we explored whether this differed according to the year of their diagnosis, for example, whether they had experienced HIV care in the pretreatment era. DESIGN: Qualitative interview study with framework analysis. SETTING: Two large HIV adult outpatient clinics in central London...
March 30, 2018: BMJ Open
https://www.readbyqxmd.com/read/29570471/retention-and-adherence-global-challenges-for-the-long-term-care-of-adolescents-and-young-adults-living-with-hiv
#3
Leslie A Enane, Rachel C Vreeman, Caroline Foster
PURPOSE OF REVIEW: Adolescents living with HIV are the only age group with increasing HIV mortality at a time of global scale-up of access to antiretroviral therapy (ART). As a 'treat all' strategy is implemented worldwide, it is critically important to optimize retention and adherence for this vulnerable group. RECENT FINDINGS: Adolescents and young adults living with HIV have poorer outcomes when compared with adults at each stage of the HIV care cascade, irrespective of income setting...
March 22, 2018: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/29558896/challenges-and-successes-in-the-implementation-of-option-b-to-prevent-mother-to-child-transmission-of-hiv-in-southern-swaziland
#4
David Etoori, Bernhard Kerschberger, Nelly Staderini, Mpumelelo Ndlangamandla, Bonisile Nhlabatsi, Kiran Jobanputra, Simangele Mthethwa-Hleza, Lucy Anne Parker, Sifiso Sibanda, Edwin Mabhena, Munyaradzi Pasipamire, Serge Mathurin Kabore, Barbara Rusch, Christine Jamet, Iza Ciglenecki, Roger Teck
BACKGROUND: Universal antiretroviral therapy (ART) for all pregnant/ breastfeeding women living with Human Immunodeficiency Virus (HIV), known as Prevention of mother-to child transmission of HIV (PMTCT) Option B+ (PMTCTB+), is being scaled up in most countries in Sub-Saharan Africa. In the transition to PMTCTB+, many countries face challenges with proper implementation of the HIV care cascade. We aimed to describe the feasibility of a PMTCTB+ approach in the public health sector in Swaziland...
March 20, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29544597/a-scoping-review
#5
Elan Lazuardi, Stephen Bell, Christy E Newman
Background: The Indonesian response to HIV has been informed largely by quantitative evidence. This review examines what is known about the Indonesian HIV care cascade from published qualitative research. Methods: A 'scoping review' method was used to synthesise and interpret the findings of 17 eligible peer-reviewed publications. Results: Qualitative findings are reported in relation to two themes. Factors influencing successful engagement include a lack of HIV-related knowledge among clients, fear of stigma or lack of privacy/confidentiality at services, limited accessibility and affordability, and poor linkages between services...
March 16, 2018: Sexual Health
https://www.readbyqxmd.com/read/29543857/is-substance-use-associated-with-hiv-cascade-outcomes-in-latin-america
#6
Raquel B De Boni, Meridith B Peratikos, Bryan E Shepherd, Beatriz Grinsztejn, Claudia Cortés, Denis Padgett, Eduardo Gotuzzo, Pablo F Belaunzarán-Zamudio, Peter F Rebeiro, Stephany N Duda, Catherine C McGowan
BACKGROUND: The HIV care cascade has improved in Latin America over the last decade. However, the influence of alcohol and noninjected drug use (NIDU) on cascade outcomes is mostly unknown. This study estimated the association of alcohol and NIDU with retention in care, loss to follow up (LTFU), and virologic failure (VF). METHODS: Individuals ≥18 years attending routine HIV clinic visits and completing the Rapid Screening Tool (RST; evaluating NIDU and ART adherence in 7-day recall period) during 2012-13 were followed up to 2015 in the Caribbean, Central and South America network for HIV epidemiology...
2018: PloS One
https://www.readbyqxmd.com/read/29526609/assessing-effects-of-behavioral-intervention-on-treatment-outcomes-among-patients-initiating-hiv-care-rationale-and-design-of-iengage-intervention-trial
#7
R Modi, K R Amico, A Knudson, A O Westfall, J Keruly, H M Crane, E B Quinlivan, C Golin, J Willig, A Zinski, R Moore, S Napravnik, L Bryan, M S Saag, M J Mugavero
In the first year after HIV diagnosis, patients are simultaneously processing with their diagnosis, typically with an emotional component, while also developing a routine of regular medical care visits and antiretroviral therapy (ART) adherence. Maintaining "HIV adherence" and integrating it into one's daily life is required to sustain viral load suppression (VS) over time. The HIV care continuum or "treatment cascade," an epidemiological snapshot of the national epidemic in the United States (US), indicates that a minority of persons living with HIV (PLWH) have achieved VS...
March 8, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29509839/effect-of-offering-same-day-art-vs-usual-health-facility-referral-during-home-based-hiv-testing-on-linkage-to-care-and-viral-suppression-among-adults-with-hiv-in-lesotho-the-cascade-randomized-clinical-trial
#8
Niklaus D Labhardt, Isaac Ringera, Thabo I Lejone, Thomas Klimkait, Josephine Muhairwe, Alain Amstutz, Tracy R Glass
Importance: Home-based HIV testing is a frequently used strategy to increase awareness of HIV status in sub-Saharan Africa. However, with referral to health facilities, less than half of those who test HIV positive link to care and initiate antiretroviral therapy (ART). Objective: To determine whether offering same-day home-based ART to patients with HIV improves linkage to care and viral suppression in a rural, high-prevalence setting in sub-Saharan Africa. Design, Setting, and Participants: Open-label, 2-group, randomized clinical trial (February 22, 2016-September 17, 2017), involving 6 health care facilities in northern Lesotho...
March 6, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29499704/hiv-status-disclosure-to-male-partners-among-rural-nigerian-women-along-the-prevention-of-mother-to-child-transmission-of-hiv-cascade-a-mixed-methods-study
#9
Angela Odiachi, Salome Erekaha, Llewellyn J Cornelius, Christopher Isah, Habib O Ramadhani, Laura Rapoport, Nadia A Sam-Agudu
BACKGROUND: HIV status disclosure to male partners is important for optimal outcomes in the prevention of mother-to-child transmission of HIV (PMTCT). Depending on timing of HIV diagnosis or pregnancy status, readiness to disclose and disclosure rates may differ among HIV-positive women. We sought to determine rates, patterns, and experiences of disclosure among Nigerian women along the PMTCT cascade. METHODS: HIV-positive women in rural North-Central Nigeria were purposively recruited according to their PMTCT cascade status: pregnant-newly HIV-diagnosed, pregnant-in care, postpartum, and lost-to-follow-up (LTFU)...
March 2, 2018: Reproductive Health
https://www.readbyqxmd.com/read/29490957/do-female-sex-workers-have-lower-uptake-of-hiv-treatment-services-than-non-sex-workers-a-cross-sectional-study-from-east-zimbabwe
#10
Rebecca Rhead, Jocelyn Elmes, Eloghene Otobo, Kundai Nhongo, Albert Takaruza, Peter J White, Constance Anesu Nyamukapa, Simon Gregson
OBJECTIVE: Globally, HIV disproportionately affects female sex workers (FSWs) yet HIV treatment coverage is suboptimal. To improve uptake of HIV services by FSWs, it is important to identify potential inequalities in access and use of care and their determinants. Our aim is to investigate HIV treatment cascades for FSWs and non-sex workers (NSWs) in Manicaland province, Zimbabwe, and to examine the socio-demographic characteristics and intermediate determinants that might explain differences in service uptake...
February 28, 2018: BMJ Open
https://www.readbyqxmd.com/read/29490955/estimating-the-hiv-undiagnosed-population-in-catalonia-spain-descriptive-and-comparative-data-analysis-to-identify-differences-in-msm-stratified-by-migrant-and-spanish-born-population
#11
Juliana Maria Reyes-Urueña, Colin N J Campbell, Núria Vives, Anna Esteve, Juan Ambrosioni, Cristina Tural, Elena Ferrer, Gemma Navarro, Lluis Force, Isabel García, Àngels Masabeu, Josep M Vilaró, Patricia García de Olalla, Joan Artur Caylà, Josep M Miró, Jordi Casabona
OBJECTIVE: Undiagnosed HIV continues to be a hindrance to efforts aimed at reducing incidence of HIV. The objective of this study was to provide an estimate of the HIV undiagnosed population in Catalonia and compare the HIV care cascade with this step included between high-risk populations. METHODS: To estimate HIV incidence, time between infection and diagnosis and the undiagnosed population stratified by CD4 count, we used the ECDC HIV Modelling Tool V.1.2.2. This model uses data on new HIV and AIDS diagnoses from the Catalan HIV/AIDS surveillance system from 2001 to 2013...
February 28, 2018: BMJ Open
https://www.readbyqxmd.com/read/29487471/nurturing-the-continuum-of-hiv-testing-treatment-and-prevention-matrix-cascade-in-reducing-hiv-transmission
#12
Clarence S Yah
Background: Despite the shift in antiretroviral therapy (ARVs) eligibility cascade from CD4 ≤ 200 to CD4 ≤ 350 to CD4 ≤ 500 mm3 , HIV related morbidity and mortality continue to escalate annually, as do HIV infections. The new paradigm of treatment for all HIV positives individual irrespective of CD4 count may significantly reduce HIV and related illnesses. The author assumes that all HIV infected partners should be eligible for HIV treatment and care, irrespective of CD4 count...
November 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29486818/predictors-of-retention-in-care-in-hiv-infected-patients-in-a-large-hospital-cohort-in-italy
#13
Roberta Prinapori, Barbara Giannini, Niccolò Riccardi, Francesca Bovis, Mauro Giacomini, Maurizio Setti, Claudio Viscoli, Stefania Artioli, Antonio Di Biagio
Retention in care is a key feature of the cascade of continuum of care, playing an important role in achieving therapeutic success and being crucial for reduction of HIV transmission. The aim of this study was to evaluate the rate of retention in care in a large referral centre in the North of Italy and to identify predictors associated with failed retention. All new HIV-infected subjects were consecutive enrolled from 1 January 2008 to 31 December 2014. Demographics, immune-virological status, hepatitis co-infection and timing of initiation of combined antiretroviral therapy (cART) data were collected at baseline and at the time of last observation...
February 28, 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29460226/genetic-cluster-analysis-for-hiv-prevention
#14
REVIEW
Mary Kate Grabowski, Joshua T Herbeck, Art F Y Poon
PURPOSE OF REVIEW: This review summarizes the use of genetic similarity clusters to understand HIV transmission and inform prevention efforts. RECENT FINDINGS: Recent emphases include the development of real-time cluster identification in order to interrupt transmission chains, the use of clusters to estimate rates of transmission along the HIV care cascade, and the extension of cluster analyses to understand transmission in the generalized epidemics of sub-Saharan Africa...
February 19, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29458337/hiv-1-transmission-and-survival-according-to-feeding-options-in-infants-born-to-hiv-infected-women-in-yaound%C3%A3-cameroon
#15
Anne Esther Njom Nlend, Annie Carole Nga Motaze, Arsene Sandie, Joseph Fokam
BACKGROUND: Evidence of 24-months survival in the frame of prevention of mother-to-child transmission (PMTCT) cascade-care is scare from routine programs in sub-Saharan African (SSA) settings. Specifically, data on infant outcomes according to feeding options remain largely unknown by month-24, thus limiting its breath for public-health recommendations toward eliminating new pediatric HIV-1 infections and improving care. We sought to evaluate HIV-1 vertical transmission and infant survival rates according to feeding options...
February 19, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29454322/using-ehealth-to-engage-and-retain-priority-populations-in-the-hiv-treatment-and-care-cascade-in-the-asia-pacific-region-a-systematic-review-of-literature
#16
Julianita Purnomo, Katherine Coote, Limin Mao, Ling Fan, Julian Gold, Raghib Ahmad, Lei Zhang
BACKGROUND: The exponential growth in the reach and development of new technologies over the past decade means that mobile technologies and social media play an increasingly important role in service delivery models to maximise HIV testing and access to treatment and care. This systematic review examines the impact of electronic and mobile technologies in medical care (eHealth) in the linkage to and retention of priority populations in the HIV treatment and care cascade, focussing on the Asia-Pacific region...
February 17, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29438439/mother-to-child-transmission-of-hiv-in-brazil-data-from-the-birth-in-brazil-study-a-national-hospital-based-study
#17
Rosa Maria Soares Madeira Domingues, Valeria Saraceni, Maria do Carmo Leal
AIMS: to estimate the mother to child transmission (MTCT) of HIV among infected pregnant women identified in the "Birth in Brazil" study and to evaluate care practices provided in order to identify missed opportunities at preventing the MTCT of HIV infection in the country. METHODS: Descriptive study using data obtained from the consultation of different databases: the "Birth in Brazil" study database and the Brazilian National Information Systems (NIS) databases...
2018: PloS One
https://www.readbyqxmd.com/read/29381257/completion-of-the-tuberculosis-care-cascade-in-a-community-based-hiv-linkage-to-care-study-in-south-africa-and-uganda
#18
Adrienne E Shapiro, Alastair van Heerden, Torin T Schaafsma, James P Hughes, Jared M Baeten, Heidi van Rooyen, Elioda Tumwesigye, Connie L Celum, Ruanne V Barnabas
INTRODUCTION: Tuberculosis (TB) is the leading cause of HIV-associated mortality in Africa. As HIV testing, linkage to care and antiretroviral treatment initiation intensify to meet UNAIDS targets, it is not known what effect these efforts will have on TB detection and prevention. We aimed to characterize the TB care cascade of screening, diagnostic testing, treatment and provision of isoniazid preventive therapy (IPT) in a study of community-based HIV screening and linkage to care and determine whether symptom screening results affected progress along the cascade...
January 2018: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29378622/maximizing-adherence-and-retention-for-women-living-with-hiv-and-their-infants-in-kenya-motivate-study-study-protocol-for-a-randomized-controlled-trial
#19
Thomas A Odeny, Maricianah Onono, Kevin Owuor, Anna Helova, Iris Wanga, Elizabeth A Bukusi, Janet M Turan, Lisa L Abuogi
BACKGROUND: Successful completion and retention throughout the multi-step cascade of prevention of mother-to-child HIV transmission (PMTCT) remains difficult to achieve. The Mother and Infant Visit Adherence and Treatment Engagement study aims to evaluate the effect of mobile text messaging, community-based mentor mothers (cMMs), or both on increasing antiretroviral therapy (ART) adherence, retention in HIV care, maternal viral load suppression, and mother-to-child HIV transmission for mother-infant pairs receiving lifelong ART...
January 29, 2018: Trials
https://www.readbyqxmd.com/read/29369949/using-choice-architecture-to-integrate-substance-use-services-with-primary-care-commentary-on-donohue-et-al
#20
Leo Beletsky
: At a time when death and disability linked to problematic substance use have reached crisis levels, integration of substance use disorder (SUD) services into primary care settings is a clear national priority. Incentive-based interventions can catalyze such adoption, but have thus far demonstrated limited efficaciousness. Behavioral Economics can inform efforts to incentivize healthcare providers to adopt SUD interventions. Choice architecture principles dictate pegging rewards to defined quality metrics, improving provider information about effective and cost-effective practices, and reducing barriers to SUD service provision through technological tools, tackling stigma, and addressing real and perceived regulatory burdens and risks...
February 2018: Journal of Addiction Medicine
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