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Continuum of HIV care

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https://www.readbyqxmd.com/read/27906994/enhancing-hiv-testing-and-treatment-among-men-who-have-sex-with-men-in-china-a-pilot-model-with-two-rapid-tests-single-blood-draw-session-and-intensified-case-management-in-six-cities-in-2013
#1
Dapeng Zhang, Hongyan Lu, Minghua Zhuang, Guohui Wu, Hongjing Yan, Jun Xu, Xiaoli Wei, Chengmei Li, Sining Meng, Xiaojing Fu, Jinlei Qi, Peng Wang, Mei Luo, Min Dai, Ray Yip, Jiangping Sun, Zunyou Wu
OBJECTIVES: To explore models to improve HIV testing, linkage to care and treatment among men who have sex with men (MSM) in cooperation with community-based organizations (CBOs) in China. METHODS: We introduced a new model for HIV testing services targeting MSM in six cities in 2013.These models introduced provision of rapid HIV testing by CBO staff and streamlined processes for HIV screening, confirmation of initial reactive screening results, and linkage to care among diagnosed people...
2016: PloS One
https://www.readbyqxmd.com/read/27906057/the-hiv-treatment-cascade-and-care-continuum-updates-goals-and-recommendations-for-the-future
#2
REVIEW
Emma Sophia Kay, D Scott Batey, Michael J Mugavero
The HIV care continuum is a framework that models the dynamic stages of HIV care. The continuum consists of five main steps, which, at the population level, are depicted cross-sectionally as the HIV treatment cascade. These steps include diagnosis, linkage to care (LTC), retention in care (RiC), adherence to antiretroviral therapy (ART), and viral suppression. Although the HIV treatment cascade is represented as a linear, unidirectional framework, persons living with HIV (PLWH) often experience the care continuum in a less streamlined fashion, skip steps altogether, or even exit the continuum for a period of time and regress to an earlier stage...
November 8, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27906029/trends-in-clinical-characteristics-and-outcomes-of-pre-art-care-at-a-large-hiv-clinic-in-nairobi-kenya-a-retrospective-cohort-study
#3
Jared O Mecha, Elizabeth N Kubo, Lucy W Nganga, Peter N Muiruri, Lilian N Njagi, Immaculate N Mutisya, Justine J Odionyi, Syokau C Ilovi, Mary Wambui, Christopher Githu, Richard Ngethe, Elizabeth M Obimbo, Zipporah W Ngumi
BACKGROUND: The success of antiretroviral therapy in resource-scarce settings is an illustration that complex healthcare interventions can be successfully delivered even in fragile health systems. Documenting the success factors in the scale-up of HIV care and treatment in resource constrained settings will enable health systems to prepare for changing population health needs. This study describes changing demographic and clinical characteristics of adult pre-ART cohorts, and identifies predictors of pre-ART attrition at a large urban HIV clinic in Nairobi, Kenya...
November 14, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27905895/mortality-along-the-continuum-of-hiv-care-in-rwanda-a-model-based-analysis
#4
Eran Bendavid, David Stauffer, Eric Remera, Sabin Nsanzimana, Steve Kanters, Edward J Mills
BACKGROUND: HIV is the leading cause of death among adults in sub-Saharan Africa. However, mortality along the HIV care continuum is poorly described. We combine demographic, epidemiologic, and health services data to estimate where are people with HIV dying along Rwanda's care continuum. METHODS: We calibrated an age-structured HIV disease and transmission stochastic simulation model to the epidemic in Rwanda. We estimate mortality among HIV-infected individuals in the following states: untested, tested without establishing care in an antiretroviral therapy (ART) program (unlinked), in care before initiating ART (pre-ART), lost to follow-up (LTFU) following ART initiation, and retained in active ART care...
December 1, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27895697/trends-in-clinical-characteristics-and-outcomes-of-pre-art-care-at-a-large-hiv-clinic-in-nairobi-kenya-a-retrospective-cohort-study
#5
Jared O Mecha, Elizabeth N Kubo, Lucy W Nganga, Peter N Muiruri, Lilian N Njagi, Immaculate N Mutisya, Justine J Odionyi, Syokau C Ilovi, Mary Wambui, Christopher Githu, Richard Ngethe, Elizabeth M Obimbo, Zipporah W Ngumi
BACKGROUND: The success of antiretroviral therapy in resource-scarce settings is an illustration that complex healthcare interventions can be successfully delivered even in fragile health systems. Documenting the success factors in the scale-up of HIV care and treatment in resource constrained settings will enable health systems to prepare for changing population health needs. This study describes changing demographic and clinical characteristics of adult pre-ART cohorts, and identifies predictors of pre-ART attrition at a large urban HIV clinic in Nairobi, Kenya...
2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27872322/hiv-care-and-treatment-of-american-indians-alaska-natives-with-diagnosed-hiv-infection-27-states-and-the-district-of-columbia-2012
#6
Andrew Mitsch, Aruna Surendera Babu, Dean Seneca, Y Omar Whiteside, Donald Warne
The objective of this study was to measure linkage to care, retention in care, and suppressed viral load (VL) among American Indians/Alaska Natives (AIs/ANs) aged ≥13 years with diagnosed HIV infection. We used national HIV case surveillance data to measure linkage to care, defined as ≥1 CD4 or VL test ≤1 month after HIV diagnosis during 2013; retention in care, defined as ≥2 CD4 or VL tests ≥3 months apart during 2012; and suppressed VL, defined as <200 copies/mL at the most recent VL test during 2012...
November 21, 2016: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/27869303/acute-care-an-important-component-of-the-continuum-of-care-for-hiv-and-tuberculosis-in-developing-countries
#7
EDITORIAL
P Bock, H Cox
No abstract text is available yet for this article.
November 21, 2016: Anaesthesia
https://www.readbyqxmd.com/read/27863535/towards-an-integrated-primary-and-secondary-hiv-prevention-continuum-for-the-united-states-a-cyclical-process-model
#8
Tim Horn, Jennifer Sherwood, Robert H Remien, Denis Nash, Judith D Auerbach
INTRODUCTION: Every new HIV infection is preventable and every HIV-related death is avoidable. As many jurisdictions around the world endeavour to end HIV as an epidemic, missed HIV prevention and treatment opportunities must be regarded as public health emergencies, and efforts to quickly fill gaps in service provision for all people living with and vulnerable to HIV infection must be prioritized. DISCUSSION: We present a novel, comprehensive, primary and secondary HIV prevention continuum model for the United States as a conceptual framework to identify key steps in reducing HIV incidence and improving health outcomes among those vulnerable to, as well as those living with, HIV infection...
2016: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/27849370/reengagement-in-care-after-a-gap-in-hiv-care-among-a-population-of-privately-insured-persons-with-hiv-in-the-united-states
#9
Kathy K Byrd, Melissa Furtado, Tim Bush, Lytt Gardner
The HIV care continuum illustrates steps needed to reach HIV viral suppression, including retention in care. The continuum's retention measure does not account for gaps or reengagement in care and thus provides an incomplete picture of long-term engagement. We used a claims database to determine the proportion of privately insured persons with HIV who experienced a gap in care and subsequently reengaged between 2008 and 2012. A gap was defined as no office visit claim in >6 months and reengagement as ≥1 office visit claim after a gap...
November 2016: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/27844296/the-role-of-the-primary-romantic-relationship-in-hiv-care-engagement-outcomes-among-young-hiv-positive-black-men-who-have-sex-with-men
#10
Judy Y Tan, Lance Pollack, Greg Rebchook, John Peterson, David Huebner, Agatha Eke, Wayne Johnson, Susan Kegeles
The primary romantic relationship plays a fundamental role in health maintenance, but little is known about its role in HIV care engagement among young Black men who have sex with men (MSM) living with HIV. We examined how HIV care engagement outcomes (i.e., having a primary healthcare provider, receiving HIV treatment, taking antiretroviral medication, and medication adherence) vary by partnership status (single vs. concordant-positive vs. discordant) in a sample of young Black MSM living with HIV. Results showed mixed findings...
November 14, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/27842543/design-of-the-indian-nca-study-indian-national-collaboration-on-aids-a-cluster-randomized-trial-to-evaluate-the-effectiveness-of-integrated-care-centers-to-improve-hiv-outcomes-among-men-who-have-sex-with-men-and-persons-who-inject-drugs-in-india
#11
Sunil S Solomon, Gregory M Lucas, David D Celentano, Allison M McFall, Elizabeth Ogburn, Lawrence H Moulton, Aylur K Srikrishnan, M Suresh Kumar, Santhanam Anand, Suniti Solomon, Shruti H Mehta
BACKGROUND: Globally, men who have sex with men and people who inject drugs remain disproportionately affected by HIV, but they have not been the focus of prevention and treatment interventions in many resource-limited settings. METHODS/DESIGN: This cluster-randomized trial (conducted from June 2012 to June 2017), evaluates whether single-venue, integrated delivery of core HIV services to vulnerable high-risk populations improves service utilization and consequently, HIV testing and other outcomes along the HIV care continuum...
November 14, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27826353/the-hiv-treatment-cascade-and-care-continuum-updates-goals-and-recommendations-for-the-future
#12
REVIEW
Emma Sophia Kay, D Scott Batey, Michael J Mugavero
The HIV care continuum is a framework that models the dynamic stages of HIV care. The continuum consists of five main steps, which, at the population level, are depicted cross-sectionally as the HIV treatment cascade. These steps include diagnosis, linkage to care (LTC), retention in care (RiC), adherence to antiretroviral therapy (ART), and viral suppression. Although the HIV treatment cascade is represented as a linear, unidirectional framework, persons living with HIV (PLWH) often experience the care continuum in a less streamlined fashion, skip steps altogether, or even exit the continuum for a period of time and regress to an earlier stage...
2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27802839/the-prevalence-and-associated-factors-for-delayed-presentation-for-hiv-care-among-tuberculosis-hiv-co-infected-patients-in-southwest-ethiopia-a-retrospective-observational-cohort
#13
Hailay Gesesew, Birtukan Tsehaineh, Desalegn Massa, Amanuel Tesfay, Hafte Kahsay, Lillian Mwanri
BACKGROUND: A delay presentation for human immunodeficiency virus (HIV) patient's care (that is late engagement to HIV care due to delayed HIV testing or delayed linkage for HIV care after the diagnosis of HIV positive) is a critical step in the series of HIV patient care continuum. In Ethiopia, delayed presentation (DP) for HIV care among vulnerable groups such as tuberculosis (Tb) /HIV co-infected patients has not been assessed. We aimed to assess the prevalence of and factors associated with DP (CD4 < 200 cells/μl at first visit) among Tb/HIV co-infected patients in southwest Ethiopia...
November 2, 2016: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/27792684/optimizing-infant-hiv-diagnosis-in-resource-limited-settings-modeling-the-impact-of-hiv-dna-pcr-testing-at-birth
#14
Alexander Chiu, Surbhi Modi, Emilia D Rivadeneira, Emilia H Koumans
BACKGROUND: Early antiretroviral therapy (ART) initiation in HIV-infected infants significantly improves survival but is often delayed in resource-limited settings. Adding HIV testing of infants at birth to the current recommendation of testing at age 4-6 weeks may improve testing rates and decrease time to ART initiation. We modeled the benefit of adding HIV testing at birth to the current 6-week testing algorithm. METHODS: Microsoft Excel was used to create a decision-tree model of the care continuum for the estimated 1,400,000 HIV-infected women and their infants in sub-Saharan Africa in 2012...
December 1, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27774350/the-art-of-hiv-elimination-past-and-present-science
#15
Collins C Iwuji, Nuala McGrath, Tulio de Oliveira, Kholoud Porter, Deenan Pillay, Martin Fisher, Melanie Newport, Marie-Louise Newell
INTRODUCTION: Remarkable strides have been made in controlling the HIV epidemic, although not enough to achieve epidemic control. More recently, interest in biomedical HIV control approaches has increased, but substantial challenges with the HIV cascade of care hinder successful implementation. We summarise all available HIV prevention methods and make recommendations on how to address current challenges. DISCUSSION: In the early days of the epidemic, behavioural approaches to control the HIV dominated, and the few available evidence-based interventions demonstrated to reduce HIV transmission were applied independently from one another...
November 30, 2015: Journal of AIDS & Clinical Research
https://www.readbyqxmd.com/read/27768710/loss-to-follow-up-from-hiv-screening-to-art-initiation-in-rural-china
#16
Diane Gu, Yurong Mao, Zhenzhu Tang, Julio Montaner, Zhiyong Shen, Qiuying Zhu, Roger Detels, Xia Jin, Ran Xiong, Juan Xu, Walter Ling, Lynda Erinoff, Robert Lindblad, David Liu, Paul Van Veldhuisen, Albert Hasson, Zunyou Wu
BACKGROUND: Patients who are newly screened HIV positive by EIA are lost to follow-up due to complicated HIV testing procedures. Because this is the first step in care, it affects the entire continuum of care. This is a particular concern in rural China. OBJECTIVE(S): To assess the routine HIV testing completeness and treatment initiation rates at 18 county-level general hospitals in rural Guangxi. METHODS: We reviewed original hospital HIV screening records...
2016: PloS One
https://www.readbyqxmd.com/read/27763258/tuberculosis-diagnostics-state-of-the-art-and-future-directions
#17
Madhukar Pai, Mark P Nicol, Catharina C Boehme
Rapid and accurate diagnosis is critical for timely initiation of anti-tuberculosis (TB) treatment, but many people with TB (or TB symptoms) do not have access to adequate initial diagnosis. In many countries, TB diagnosis is still reliant on sputum microscopy, a test with known limitations. However, new diagnostics are starting to change the landscape. Stimulated, in part, by the success and rollout of Xpert MTB/RIF, an automated, molecular test, there is now considerable interest in new technologies. The landscape looks promising with a pipeline of new tools, particularly molecular diagnostics, and well over 50 companies actively engaged in product development, and many tests have been reviewed by WHO for policy endorsement...
October 2016: Microbiology Spectrum
https://www.readbyqxmd.com/read/27742766/the-hiv-prison-paradox-agency-and-hiv-positive-women-s-experiences-in-jail-and-prison-in-alabama
#18
Courtenay Sprague, Michael L Scanlon, Bharathi Radhakrishnan, David W Pantalone
Incarcerated women face significant barriers to achieve continuous HIV care. We employed a descriptive, exploratory design using qualitative methods and the theoretical construct of agency to investigate participants' self-reported experiences accessing HIV services in jail, in prison, and post-release in two Alabama cities. During January 2014, we conducted in-depth interviews with 25 formerly incarcerated HIV-positive women. Two researchers completed independent coding, producing preliminary codes from transcripts using content analysis...
October 14, 2016: Qualitative Health Research
https://www.readbyqxmd.com/read/27696635/antiretroviral-therapy-status-among-people-who-died-of-aids-related-causes-from-2009-to-2013-in-brazil-a-population-based-study
#19
Marcelo Araújo de Freitas, Angélica Espinosa Miranda, Ana Roberta Pati Pascom, Silvano Barbosa de Oliveira, Fabio Mesquita, Nathan Ford
OBJECTIVE: To describe the antiretroviral therapy status of people living with HIV (PLHIV) who died of AIDS-related causes between 2009 and 2013. METHODS: We conducted a cross-sectional, population-based study. Data were obtained by linking the mortality information system and the national ART dispensing database. Trends were modelled using linear regression analysis. RESULTS: A total of 61 425 AIDS-related deaths were registered in Brazil between 2009 and 2013...
October 3, 2016: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/27662544/criminal-justice-involvement-history-is-associated-with-better-hiv-care-continuum-metrics-among-a-population-based-sample-of-young-black-msm
#20
John A Schneider, Michael Kozloski, Stuart Michaels, Britt Skaathun, Dexter Voisin, Nicola Lancki, Ethan Morgan, Aditya Khanna, Keith Green, Robert W Coombs, Samuel R Friedman, Edward Laumann, Phil Schumm
OBJECTIVE: To examine how history of criminal justice involvement (CJI) is related to HIV care continuum metrics among young black MSM 16-29 years of age. DESIGN: Population-based survey. METHODS: From 2013 to 2014, a representative sample of young black MSM was generated using respondent-driven sampling (RDS) in Chicago (n = 618). HIV antibody/antigen and RNA testing were performed using dry blood spots. Factors assessed in the care continuum included HIV testing, HIV diagnosis, linkage to care within 6 months, retention in care, adherence to antiretrovirals, and viral suppression...
January 2, 2017: AIDS
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