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Continuum of HIV care

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https://www.readbyqxmd.com/read/28526661/the-parasol-protocol-an-implementation-science-study-of-hiv-continuum-of-care-interventions-for-gay-men-and-transgender-women-in-burma-myanmar
#1
Andrea L Wirtz, Soe Naing, Emily Clouse, Kaung Htet Thu, Sandra Hsu Hnin Mon, Zin Min Tun, Stefan Baral, Aung Zayar Paing, Chris Beyrer
BACKGROUND: Efforts to improve HIV diagnosis and antiretroviral therapy (ART) initiation among people living with HIV and reduce onward transmission of HIV rely on innovative interventions along multiple steps of the HIV care continuum. These innovative methods are particularly important for key populations, including men who have sex with men (MSM) and transgender women (TW). The HIV epidemic in Myanmar is concentrated among key populations, and national efforts now focus on reducing stigma and improving engagement of MSM and TW in HIV prevention and care...
May 17, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28513816/italian-guidelines-for-the-use-of-antiretroviral-agents-and-the-diagnostic-clinical-management-of-hiv-1-infected-persons-update-2016
#2
Andrea Antinori, Antonio Di Biagio, Simone Marcotullio, Massimo Andreoni, Antonio Chirianni, Antonella d'Arminio Monforte, Massimo Galli, Francesco Mazzotta, Cristina Mussini, Massimo Puoti, Adriano Lazzarin
The Italian Society of Infectious and Tropical Diseases (SIMIT) of the Technical Health Committee, Ministry of Health (Sections L and M) of Italy have supported recommendations for the Italian guidelines for the use of antiretroviral agents and the diagnostic-clinical management of HIV-1 infected persons. This publication summarizes the latest updates to the 2016 version of the Italian Guidelines for the management of HIV-1 infected patients and the use of antiretroviral drugs. In particular, new recommendations were released concerning the following topics: estimate of the HIV continuum of care in Italy, optimal timing and preferred drug combinations for starting antiretroviral therapy, treatment optimization, and pre-exposure prophilaxis (PrEP)...
April 2017: New Microbiologica
https://www.readbyqxmd.com/read/28506566/trends-in-racial-ethnic-disparities-of-new-aids-diagnoses-in-the-united-states-1984-2013
#3
Johanna Chapin-Bardales, Eli Samuel Rosenberg, Patrick Sean Sullivan
PURPOSE: In the United States, human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) disproportionately impacts racial/ethnic minorities. We describe and evaluate trends in the Black-White and Hispanic-White disparities of new AIDS diagnoses from 1984 to 2013 in the United States. METHODS: AIDS diagnosis rates by race/ethnicity for people ≥13 years were calculated using national HIV surveillance and Census data. Black-White and Hispanic-White disparities were measured as rate ratios...
April 21, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/28472928/using-the-multiphase-optimization-strategy-most-to-optimize-an-hiv-care-continuum-intervention-for-vulnerable-populations-a-study-protocol
#4
Marya Viorst Gwadz, Linda M Collins, Charles M Cleland, Noelle R Leonard, Leo Wilton, Monica Gandhi, R Scott Braithwaite, David C Perlman, Alexandra Kutnick, Amanda S Ritchie
BACKGROUND: More than half of persons living with HIV (PLWH) in the United States are insufficiently engaged in HIV primary care and not taking antiretroviral therapy (ART), mainly African Americans/Blacks and Hispanics. In the proposed project, a potent and innovative research methodology, the multiphase optimization strategy (MOST), will be employed to develop a highly efficacious, efficient, scalable, and cost-effective intervention to increase engagement along the HIV care continuum...
May 4, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28471841/a-flow-based-model-of-the-hiv-care-continuum-in-the-united-states
#5
Gregg S Gonsalves, A David Paltiel, Paul D Cleary, Michael John Gill, Mari M Kitahata, Peter F Rebeiro, Michael J Silverberg, Michael Horberg, Alison G Abraham, Keri N Althoff, Richard Moore, Ronald J Bosch, H Irene Hall, Edward H Kaplan
BACKGROUND: Understanding the flow of patients through the continuum of HIV care is critical to determine how best to intervene so that the proportion of HIV-infected persons who are on antiretroviral treatment and virally suppressed is as large as possible. METHODS: Using immunological and virological data from the Centers for Disease Control and Prevention and the North American AIDS Cohort Collaboration on Research and Design from 2009-2012, we estimated the distribution of time spent in and dropout probability from each stage in the continuum of HIV care...
April 26, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28462622/trends-in-hiv-continuum-of-care-outcomes-over-10-years-of-follow-up-at-a-large-hiv-primary-medical-home-in-the-southeastern-united-states
#6
Michael K Ghiam, Peter Rebeiro, Megan Turner, William B Rogers, Sally Bebawy, Stephen P Raffanti, Anna Kristine Person, April C Pettit
BACKGROUND: Longitudinal studies of retention in care (RIC) and viral suppression (VS) in the southeastern United States (US), a region disproportionately affected by HIV-infection, are lacking. METHODS: HIV-infected adults with ≥1 medical visit at the Vanderbilt Comprehensive Care Clinic (Nashville, Tennessee) from 2004-2013 were included. RIC was ≥2 (a) laboratory dates [CD4+ counts or HIV-1 viral loads (VL)] or (b) provider encounters and/or laboratory dates in the year of interest, ≥90 days apart...
May 2, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28453242/new-hiv-testing-technologies-in-the-context-of-a-concentrated-epidemic-and-evolving-hiv-prevention-qualitative-research-on-hiv-self-testing-among-men-who-have-sex-with-men-and-transgender-women-in-yangon-myanmar
#7
Andrea L Wirtz, Emily Clouse, Vanessa Veronese, Kaung Htet Thu, Soe Naing, Stefan D Baral, Chris Beyrer
INTRODUCTION: Global effort to increase early diagnosis and engagement in HIV care emphasize the importance of developing novel approaches to reaching those missed by traditional methods. Such needs are particularly great for men who have sex with men (MSM), transgender women (TW), and other populations who face stigma. Myanmar's HIV epidemic is concentrated among key populations and the revised National Strategy aims to reduce late diagnosis and barriers to care to curb HIV incidence among these groups...
April 25, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28449588/disparities-in-hiv-knowledge-and-attitudes-toward-biomedical-interventions-among-the-non-medical-hiv-workforce-in-the-united-states
#8
Raniyah M Copeland, Phill Wilson, Gabriela Betancourt, David Garcia, Murray Penner, Rebecca Abravanel, Eric Y Wong, Lori D Parisi
Non-medical, community-based workers play a critical role in supporting people living with (or at risk of acquiring) HIV along the care continuum. The biomedical nature of promising advances in HIV prevention, such as pre-exposure prophylaxis and treatment-as-prevention, requires frontline workers to be knowledgeable about HIV science and treatment. This study was developed to: measure knowledge of HIV science and treatment within the HIV non-medical workforce, evaluate workers' familiarity with and attitudes toward recent biomedical interventions, and identify factors that may affect HIV knowledge and attitudes...
April 27, 2017: AIDS Care
https://www.readbyqxmd.com/read/28446232/continuous-quality-improvement-interventions-to-improve-long-term-outcomes-of-antiretroviral-therapy-in-women-who-initiated-therapy-during-pregnancy-or-breastfeeding-in-the-democratic-republic-of-congo-design-of-an-open-label-parallel-group-randomized-trial
#9
Marcel Yotebieng, Frieda Behets, Bienvenu Kawende, Noro Lantoniaina Rosa Ravelomanana, Martine Tabala, Emile W Okitolonda
BACKGROUND: Despite the rapid adoption of the World Health Organization's 2013 guidelines, children continue to be infected with HIV perinatally because of sub-optimal adherence to the continuum of HIV care in maternal and child health (MCH) clinics. To achieve the UNAIDS goal of eliminating mother-to-child HIV transmission, multiple, adaptive interventions need to be implemented to improve adherence to the HIV continuum. METHODS: The aim of this open label, parallel, group randomized trial is to evaluate the effectiveness of Continuous Quality Improvement (CQI) interventions implemented at facility and health district levels to improve retention in care and virological suppression through 24 months postpartum among pregnant and breastfeeding women receiving ART in MCH clinics in Kinshasa, Democratic Republic of Congo...
April 26, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28445303/lifetime-and-recent-alcohol-use-and-bone-mineral-density-in-adults-with-hiv-infection-and-substance-dependence
#10
Alicia S Ventura, Michael R Winter, Timothy C Heeren, Meg M Sullivan, Alexander Y Walley, Michael F Holick, Gregory J Patts, Seville M Meli, Jeffrey H Samet, Richard Saitz
Low bone mineral density (BMD) is common in people living with HIV infection (PLWH), increasing fracture risk. Alcohol use is also common in PLWH and is a modifiable risk factor for both HIV disease progression and low BMD. In PLWH, alcohol's effect on BMD is not well understood.We studied adult PLWH with substance dependence. We measured lifetime alcohol use (kg) and recent (i.e., past 30-day) alcohol use (categorized as: abstinent, low risk, or high risk). In adjusted multivariable regression analyses, we tested associations between lifetime and recent alcohol use and (i) mean BMD (g/cm) at the femoral neck, total hip, and lumbar spine and (ii) low BMD diagnosis (i...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28443678/outcomes-along-the-hiv-care-continuum-among-undocumented-immigrants-in-clinical-care
#11
Jonathan Ross, Uriel R Felsen, Chinazo O Cunningham, Viraj V Patel, David B Hanna
HIV-infected undocumented immigrants face unique barriers to care yet little is known about their clinical outcomes. We performed a retrospective cohort study of HIV-infected adults in clinical care from 2006-2014 at a large academic medical center in a setting where medical insurance is available to HIV-infected undocumented immigrants. Undocumented status was assessed based on Social Security number and insurance status and verified through medical chart review. Using Poisson regression models, we compared undocumented and documented patients with respect to retention in care (≥ 2 HIV-related lab tests ≥ 90 days apart), antiretroviral therapy (ART) prescription (≥ 3 active antiretroviral agents prescribed in a year) and viral suppression (HIV RNA <200 copies/ml for the last measured viral load) for each year in care...
April 26, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28406271/the-relationship-between-higher-social-trust-and-lower-late-hiv-diagnosis-and-mortality-differs-by-race-ethnicity-results-from-a-state-level-analysis
#12
Yusuf Ransome, Ashley Batson, Sandro Galea, Ichiro Kawachi, Denis Nash, Kenneth H Mayer
INTRODUCTION: Black men who have sex with men (MSM) continue to suffer a disproportionate burden of new HIV diagnoses and mortality. To better understand some of the reasons for these profound disparities, we examined whether the association between social trust and late HIV diagnosis and mortality differed by race/ethnicity, and investigated potential indirect effects of any observed differences. METHODS: We performed generalized structural equation modelling to assess main and interaction associations between trust among one's neighbours in 2009 (i...
April 6, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28398994/using-the-pmtct-cascade-to-accelerate-achievement-of-the-global-plan-goals
#13
Elizabeth Hamilton, Bernard Bossiky, John Ditekemena, Godfrey Esiru, Franck Fwamba, Ameena E Goga, Mary Pat Kieffer, Landry D Tsague, Roland van de Ven, Rose Wafula, Laura Guay
BACKGROUND: Development of country plans for prevention of mother-to-child HIV transmission (PMTCT), including expansion of comprehensive, integrated services, was key to Global Plan achievements. APPROACHES: Use of the PMTCT cascade, an evolving series of sequential steps needed to maximize the health of women and HIV-free survival of infants, was critical for development and implementation of PMTCT plans. Regular review of cascade data at national/subnational levels was a tool for evidence-based decision making, identifying areas of greatest need at each level, and targeting program interventions to address specific gaps...
May 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28394820/the-north-carolina-hiv-bridge-counselor-program-outcomes-from-a-statewide-level-intervention-to-link-and-re-engage-hiv-infected-persons-in-care-in-the-south
#14
Arlene C Seña, Jenna Donovan, Heidi Swygard, Jacquelyn Clymore, Victoria Mobley, Kristen Sullivan, Anna LeViere, Amy Heine, Evelyn Byrd Quinlivan
BACKGROUND: To improve the HIV continuum of care, a team of field service interventionists (State Bridge Counselors, SBC) was developed through a state public health system, and provided brief (1-2) contacts for linkage of newly diagnosed persons with HIV and reengagement of persons living with HIV (PLWH) who were not in care. SETTING: North Carolina (NC), USA METHODS:: Service data from January 2013 - June 2015 were analyzed to determine characteristics of clients referred to SBCs, proportions linked or re-engaged in care, and/or achieved viral load suppression (VLs)...
April 6, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28376085/status-and-methodology-of-publicly-available-national-hiv-care-continua-and-90-90-90-targets-a-systematic-review
#15
REVIEW
Reuben Granich, Somya Gupta, Irene Hall, John Aberle-Grasse, Shannon Hader, Jonathan Mermin
BACKGROUND: In 2014, the Joint United Nations Program on HIV/AIDS (UNAIDS) issued treatment goals for human immunodeficiency virus (HIV). The 90-90-90 target specifies that by 2020, 90% of individuals living with HIV will know their HIV status, 90% of people with diagnosed HIV infection will receive antiretroviral treatment (ART), and 90% of those taking ART will be virally suppressed. Consistent methods and routine reporting in the public domain will be necessary for tracking progress towards the 90-90-90 target...
April 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28369283/the-hiv-continuum-of-care-in-european-union-countries-in-2013-data-and-challenges
#16
Annabelle Gourlay, Teymur Noori, Anastasia Pharris, Maria Axelsson, Dominique Costagliola, Susan Cowan, Sara Croxford, Antonella d'Arminio Monforte, Julia Del Amo, Valerie Delpech, Asunción Díaz, Enrico Girardi, Barbara Gunsenheimer-Bartmeyer, Victoria Hernando, Sophie Jose, Gisela Leierer, Georgios Nikolopoulos, Niels Obel, Eline Op de Coul, Dimitra Paraskeva, Peter Reiss, Caroline Sabin, André Sasse, Daniela Schmid, Anders Sonnerborg, Alexander Spina, Barbara Suligoi, Virginie Supervie, Giota Touloumi, Dominique Van Beckhoven, Ard van Sighem, Georgia Vourli, Robert Zangerle, Kholoud Porter
Background: UNAIDS has set a 90-90-90 target to curb the HIV epidemic by 2020, but methods used to assess whether countries have reached this target are not standardised, hindering comparisons. Methods: Through a collaboration formed by the European Centre for Disease Prevention and Control (ECDC) with European HIV cohorts and surveillance agencies, we constructed a standardised, four-stage continuum of HIV care for 11 European Union (EU) countries for 2013. Stages were defined as: 1) number of people living with HIV (PLHIV) in the country by end of 2013; 2) proportion of stage 1 ever diagnosed; 3) proportion of stage 2 ever initiated ART; and 4) proportion of stage 3 who became virally-suppressed (≤200 copies/mL)...
March 20, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28368951/effects-of-a-laboratory-health-information-exchange-intervention-on-antiretroviral-therapy-use-viral-suppression-and-racial-ethnic-disparities
#17
William E Cunningham, Chandra L Ford, Janni J Kinsler, Danielle Seiden, Laral Andrews, Terry Nakazono, Douglas S Bell
BACKGROUND: Although antiretroviral therapy (ART) is available to treat HIV+ persons and prevent transmission, ineffective delivery of care may delay ART use, impede viral suppression (VS) and contribute to racial/ethnic disparities along the continuum of care. This study tested the effects of a bi-directional laboratory health information exchange (LHIE) intervention on each of these outcomes. METHODS: We used a quasi-experimental, interrupted time series design to examine whether the LHIE intervention improved ART use and VS, and reduced racial/ethnic disparities in these outcomes among HIV+ patients (N=1,181) in a comprehensive HIV/AIDS clinic in Southern California...
March 25, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28368523/the-continuum-of-hiv-care-in-the-urban-united-states-black-men-who-have-sex-with-men-msm-are-less-likely-than-white-msm-to-receive-antiretroviral-therapy
#18
Sten H Vermund
No abstract text is available yet for this article.
March 29, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28366556/hiv-stigma-retention-in-care-and-adherence-among-older-black-women-living-with-hiv
#19
Thurka Sangaramoorthy, Amelia M Jamison, Typhanye V Dyer
Stigma is recognized as a barrier to the prevention, care, and treatment of HIV, including engagement in the HIV care continuum. HIV stigma in older Black women may be compounded by preexisting social inequities based on gender, age, and race. Using semi-structured interviews and survey questionnaires, we explore experiences of HIV stigma, retention in care, and antiretroviral therapy (ART) adherence in 35 older Black women with HIV from Prince George's County, Maryland. Study findings indicated that older Black women experienced high levels of HIV stigma, retention in care, and ART adherence...
March 18, 2017: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/28364566/identifying-gaps-in-hiv-service-delivery-across-the-diagnosis-to-treatment-cascade-findings-from-health-facility-surveys-in-six-sub-saharan-countries
#20
Kathryn Church, Kazuyo Machiyama, Jim Todd, Brian Njamwea, Mary Mwangome, Vicky Hosegood, Janet Michel, Samuel Oti, Constance Nyamukapa, Amelia Crampin, Nyaguara Amek, Gertrude Nakigozi, Denna Michael, F Xavier Gómez-Olivé, Jessica Nakiyingi-Miiro, Basia Zaba, Alison Wringe
INTRODUCTION: Despite the rollout of antiretroviral therapy (ART), challenges remain in ensuring timely access to care and treatment for people living with HIV. As part of a multi-country study to investigate HIV mortality, we conducted health facility surveys within 10 health and demographic surveillance system sites across six countries in Eastern and Southern Africa to investigate clinic-level factors influencing (i) use of HIV testing services, (ii) use of HIV care and treatment and (iii) patient retention on ART...
January 12, 2017: Journal of the International AIDS Society
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