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https://www.readbyqxmd.com/read/28628702/financial-incentives-for-linkage-to-care-and-viral-suppression-among-hiv-positive-patients-a-randomized-clinical-trial-hptn-065
#1
Wafaa M El-Sadr, Deborah Donnell, Geetha Beauchamp, H Irene Hall, Lucia V Torian, Barry Zingman, Garret Lum, Michael Kharfen, Richard Elion, Jason Leider, Fred M Gordin, Vanessa Elharrar, David Burns, Allison Zerbe, Theresa Gamble, Bernard Branson
Importance: Achieving linkage to care and viral suppression in human immunodeficiency virus (HIV)-positive patients improves their well-being and prevents new infections. Current gaps in the HIV care continuum substantially limit such benefits. Objective: To evaluate the effectiveness of financial incentives on linkage to care and viral suppression in HIV-positive patients. Design, Setting, and Participants: A large community-based clinical trial that randomized 37 HIV test and 39 HIV care sites in the Bronx, New York, and Washington, DC, to financial incentives or standard of care...
June 19, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28628349/evaluation-of-a-client-centered-linkage-intervention-for-patients-newly-diagnosed-with-hiv-at-an-urban-united-states-lgbt-center-the-linkage-to-care-specialist-project
#2
Jesse Bendetson, Rhodri Dierst-Davies, Risa Flynn, Matthew R Beymer, Amy R Wohl, K Rivet Amico, Robert K Bolan
Linkage to care (LTC) is a key element of the HIV care continuum, and a crucial bridge from testing and diagnosis to receipt of antiretroviral therapies and viral suppression. In 2012, the Los Angeles LGBT Center hired a full-time LTC specialist (LTC-S), who developed a unique client-centered approach to LTC. This single-arm demonstration project was designed to systematically evaluate the LTC-S intervention. Individuals who were newly diagnosed with HIV between March 2014 and September 2015 were eligible for enrollment...
June 19, 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28627929/design-of-the-hptn-065-tlc-plus-study-a-study-to-evaluate-the-feasibility-of-an-enhanced-test-link-to-care-plus-treat-approach-for-hiv-prevention-in-the-united-states
#3
Theresa Gamble, Bernard Branson, Deborah Donnell, H Irene Hall, Georgette King, Blayne Cutler, Shannon Hader, David Burns, Jason Leider, Angela Fulwood Wood, Kevin G Volpp, Kate Buchacz, Wafaa M El-Sadr
Background/Aims HIV continues to be a major public health threat in the United States, and mathematical modeling has demonstrated that the universal effective use of antiretroviral therapy among all HIV-positive individuals (i.e. the "test and treat" approach) has the potential to control HIV. However, to accomplish this, all the steps that define the HIV care continuum must be achieved at high levels, including HIV testing and diagnosis, linkage to and retention in clinical care, antiretroviral medication initiation, and adherence to achieve and maintain viral suppression...
June 1, 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/28622034/the-experiences-of-newly-diagnosed-men-who-have-sex-with-men-entering-the-hiv-care-cascade-in-lima-peru-2015-2016-a-qualitative-analysis-of-counselor-participant-text-message-exchanges
#4
Erik Bayona, Luis Menacho, Eddy R Segura, Gitau Mburu, Fernando Roman, Consuelo Tristan, Elizabeth Bromley, Robinson Cabello
Mobile phone technology (mHealth) is a promising tool that has been used to improve HIV care in high-risk populations worldwide. Understanding patient perspectives of newly diagnosed men who have sex with men (MSM) in Lima, Peru during linkage and engagement in the HIV care continuum can help close the gaps in care following initial HIV diagnosis and ensure retention in continuous care. From June 2015 to March 2016, as part of a randomized controlled trial, 40 MSM participants were linked to care with an mHealth intervention within 3 months of HIV diagnosis at Via Libre clinic...
June 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28604445/development-of-an-hiv-testing-dashboard-to-complement-the-hiv-care-continuum-among-msm-pwid-and-heterosexuals-in-washington-dc-2007-2015
#5
Rudy Patrick, Alan Greenberg, Manya Magnus, Jenevieve Opoku, Michael Kharfen, Irene Kuo
BACKGROUND: We developed an HIV testing dashboard to complement the HIV care continuum in selected high-risk populations. Using National HIV Behavioral Surveillance (NHBS) data, we examined trends in HIV testing and care for men who have sex with men (MSM), persons who inject drugs (PWID), and heterosexuals at elevated risk (HET). METHODS: Between 2007 and 2015, 4792 participants ≥18 years old completed a behavioral survey and were offered HIV testing. For the testing dashboard, proportions ever tested, tested in the past year, testing HIV-positive, and newly testing positive were calculated...
July 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28604439/what-factors-are-associated-with-receiving-a-recommendation-to-get-tested-for-hiv-by-health-care-providers-among-men-who-have-sex-with-men
#6
Wilson Vincent, Willi McFarland, H Fisher Raymond
BACKGROUND: The approach of treatment as prevention for reducing HIV incidence and prevalence hinges on early detection of HIV infection and treatment to achieve viral suppression and, thus, to reduce HIV transmissibility. However, men who have sex with men (MSM), who are at greater risk of HIV infection than the average adult in the United States, are often not tested because many providers do not provide routine opt-out testing or even recommend HIV testing. METHODS: In a sample of 244 MSM in San Francisco, CA, this study examined whether (1) sociodemographic characteristics (ie, youth, education, employment status, being African American, being Latino), (2) health care access and utilization, and (3) participants disclosing their sexual orientation to their health care providers were associated with their odds of having received a recommendation from a health care provider for HIV testing...
July 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28598790/croi-2017-advances-in-antiretroviral-therapy
#7
Joyce Jones, Barbara S Taylor, Hong-Van Tieu, Timothy J Wilkin
The 2017 Conference on Retroviruses and Opportunistic Infections (CROI) featured exciting preclinical data on investigational antiretroviral agents with good in vitro efficacy and long half-lives. Investigational medications, including bictegravir, demonstrated excellent efficacy and tolerability, as did dual-agent therapy with dolutegravir paired with rilpivirine or with lamivudine. Dolutegravir monotherapy proved inadvisable due to virologic failure and resistance. The gap between high- and low-income settings along the HIV care continuum is narrowing, with Zimbabwe, Malawi, and Zambia approaching the 90-90-90 targets established by the joint United Nations Programme on HIV/AIDS (UNAIDS), whereas communities in the Southern United States are falling behind...
May 2017: Topics in Antiviral Medicine
https://www.readbyqxmd.com/read/28597342/enhancing-adherence-to-care-in-the-hiv-care-continuum-the-barrier-elimination-and-care-navigation-beacon-project-evaluation
#8
Enbal Shacham, Julia D López, Tawyna M Brown, Kristen Tippit, Ann Ritz
Interventions are needed to address each phase of the HIV care continuum in order to improve health outcomes and reduce likelihood of HIV transmission. The purpose of this study was to assess the impact of a community- and clinic-based intervention designed and implemented to reengage individuals who were lost to HIV care. Eligible participants had either never engaged in HIV care or had not had a medical visit for at least 12 months. Participants enrolled in a community- and clinic-based intervention that included intensive case management, access to a community nurse and peer navigator, as well as emergency stabilization funds...
June 8, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28588949/systematic-review-and-meta-analysis-of-the-adolescent-hiv-continuum-of-care-in-south-africa-the-cresting-wave
#9
Brian C Zanoni, Moherndran Archary, Sarah Buchan, Ingrid T Katz, Jessica E Haberer
CONTEXT: South Africa has the most HIV infections of any country in the world, yet little is known about the adolescent continuum of care from HIV diagnosis through viral suppression. OBJECTIVE: To determine the adolescent HIV continuum of care in South Africa. DATA SOURCES: We searched PubMed, Google Scholar and online conference proceedings from International AIDS Society (IAS), International AIDS Conference (AIDS) and Conference on Retrovirology and Opportunistic Infections (CROI) from 1 January 2005 to 31 July 2015...
November 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28588933/can-the-unaids-90-90-90-target-be-achieved-a-systematic-analysis-of-national-hiv-treatment-cascades
#10
Jacob Levi, Alice Raymond, Anton Pozniak, Pietro Vernazza, Philipp Kohler, Andrew Hill
BACKGROUND: In 2014, the Joint United Nations Programme on HIV and AIDS (UNAIDS) and partners set the '90-90-90 targets'; aiming to diagnose 90% of all HIV positive people, provide antiretroviral therapy (ART) for 90% of those diagnosed and achieve viral suppression for 90% of those treated, by 2020. This results in 81% of all HIV positive people on treatment and 73% of all HIV positive people achieving viral suppression. We aimed to analyse how effective national HIV treatment programmes are at meeting these targets, using HIV care continuums or cascades...
August 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28578686/challenges-and-opportunities-of-optimal-breastfeeding-in-the-context-of-hiv-option-b-guidelines
#11
Pamela Marinda, Nkandu Chibwe, Ernest Tambo, Sidney Lulanga, Christopher Khayeka-Wandabwa
BACKGROUND: In 2013, the World Health Organization released a new set of guidelines widely known as Option B+. Prior to that there were guidelines released in 2010. Option B+ recommends lifelong antiretroviral treatment for all pregnant and breastfeeding women living with Human Immunodeficiency Virus. The study aimed at investigating challenges and opportunities in implementing Infant and Young Child Feeding in the context of Prevention of Mother To Child Transmission (PMTCT) guidelines among HIV positive mothers of children aged 0-24 months...
June 2, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28550380/barriers-motivators-and-facilitators-to-engagement-in-hiv-care-among-hiv-infected-ghanaian-men-who-have-sex-with-men-msm
#12
Adedotun Ogunbajo, Trace Kershaw, Sameer Kushwaha, Francis Boakye, Nii-Dromo Wallace-Atiapah, LaRon E Nelson
In Ghana, men who have sex with men (MSM) bear a high burden of HIV. Identifying factors that influence engagement in HIV care among HIV-infected Ghanaian MSM is critical to devising novel interventions and strengthening existing programs aimed at improving outcomes across the HIV care continuum. Consequently, we conducted an exploratory qualitative research study with 30 HIV-infected Ghanaian MSM between May 2015 and July 2015. Common barriers were fear of being seen in HIV-related health facility, financial difficulties, and health system challenges...
May 26, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28550379/a-mixed-methods-exploration-of-the-needs-of-people-living-with-hiv-plwh-enrolled-in-access-to-care-a-national-hiv-linkage-retention-and-re-engagement-in-medical-care-program
#13
C Maulsby, B Enobun, D S Batey, K M Jain, M Riordan, M Werner, D R Holtgrave
Competing needs pose barriers to engagement in HIV medical care. Mixed methods were used to explore and describe the needs of participants enrolled in Access to Care, a national HIV linkage, retention and re-engagement in care (LRC) program that served people living with HIV who knew their status but were not engaged in care. When asked to prioritize their most urgent needs, participants reported housing or shelter (31%), HIV medical services (24%), and employment (8%). When we assessed the HIV continuum of care by needs status, we found no significant differences in linkage, retention, or viral suppression between participants with and without basic needs...
May 26, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28531268/implementation-of-an-integrated-approach-to-the-national-hiv-aids-strategy-for-improving-human-immunodeficiency-virus-care-for-youths
#14
J Dennis Fortenberry, Linda J Koenig, Bill G Kapogiannis, Carrie L Jeffries, Jonathan M Ellen, Craig M Wilson
Importance: Youths aged 13 to 24 years old living with human immunodeficiency virus (HIV) are less likely than adults to receive the health and prevention benefits of HIV treatments, with only a small proportion having achieved sustained viral suppression. These age-related disparities in HIV continuum of care are owing in part to the unique developmental issues of adolescents and young adults as well as the complexity and fragmentation of HIV care and related services. This article summarizes a national, multiagency, and multilevel approach to HIV care for newly diagnosed youths designed to bridge some of these fragmentations by addressing National HIV/AIDS Strategy goals for people living with HIV...
May 22, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28530047/what-is-it-going-to-take-to-move-youth-related-hiv-programme-policies-into-practice-in-africa
#15
Daniella Mark, Lina Taing, Lucie Cluver, Chris Collins, Kate Iorpenda, Catarina Andrade, Luann Hatane
INTRODUCTION: HIV has been reported to be the leading cause of mortality amongst adolescents in Africa. This has brought attention to the changes in service provision and health management that many adolescents living with HIV experience when transferring from specialized paediatric- or adolescent-focused services to adult care. When transition is enacted poorly, adherence may be affected and the continuum of care disrupted. As the population of HIV-infected adolescents grows, effective and supported transition increases in significance as an operational imperative...
May 16, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28526661/the-parasol-protocol-an-implementation-science-study-of-hiv-continuum-of-care-interventions-for-gay-men-and-transgender-women-in-burma-myanmar
#16
Andrea L Wirtz, Soe Naing, Emily Clouse, Kaung Htet Thu, Sandra Hsu Hnin Mon, Zin Min Tun, Stefan Baral, Aung Zayar Paing, Chris Beyrer
BACKGROUND: Efforts to improve HIV diagnosis and antiretroviral therapy (ART) initiation among people living with HIV and reduce onward transmission of HIV rely on innovative interventions along multiple steps of the HIV care continuum. These innovative methods are particularly important for key populations, including men who have sex with men (MSM) and transgender women (TW). The HIV epidemic in Myanmar is concentrated among key populations, and national efforts now focus on reducing stigma and improving engagement of MSM and TW in HIV prevention and care...
May 17, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28513816/italian-guidelines-for-the-use-of-antiretroviral-agents-and-the-diagnostic-clinical-management-of-hiv-1-infected-persons-update-2016
#17
Andrea Antinori, Antonio Di Biagio, Simone Marcotullio, Massimo Andreoni, Antonio Chirianni, Antonella d'Arminio Monforte, Massimo Galli, Francesco Mazzotta, Cristina Mussini, Massimo Puoti, Adriano Lazzarin
The Italian Society of Infectious and Tropical Diseases (SIMIT) of the Technical Health Committee, Ministry of Health (Sections L and M) of Italy have supported recommendations for the Italian guidelines for the use of antiretroviral agents and the diagnostic-clinical management of HIV-1 infected persons. This publication summarizes the latest updates to the 2016 version of the Italian Guidelines for the management of HIV-1 infected patients and the use of antiretroviral drugs. In particular, new recommendations were released concerning the following topics: estimate of the HIV continuum of care in Italy, optimal timing and preferred drug combinations for starting antiretroviral therapy, treatment optimization, and pre-exposure prophilaxis (PrEP)...
April 2017: New Microbiologica
https://www.readbyqxmd.com/read/28506566/trends-in-racial-ethnic-disparities-of-new-aids-diagnoses-in-the-united-states-1984-2013
#18
Johanna Chapin-Bardales, Eli Samuel Rosenberg, Patrick Sean Sullivan
PURPOSE: In the United States, human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) disproportionately impacts racial/ethnic minorities. We describe and evaluate trends in the Black-White and Hispanic-White disparities of new AIDS diagnoses from 1984 to 2013 in the United States. METHODS: AIDS diagnosis rates by race/ethnicity for people ≥13 years were calculated using national HIV surveillance and Census data. Black-White and Hispanic-White disparities were measured as rate ratios...
April 21, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/28472928/using-the-multiphase-optimization-strategy-most-to-optimize-an-hiv-care-continuum-intervention-for-vulnerable-populations-a-study-protocol
#19
Marya Viorst Gwadz, Linda M Collins, Charles M Cleland, Noelle R Leonard, Leo Wilton, Monica Gandhi, R Scott Braithwaite, David C Perlman, Alexandra Kutnick, Amanda S Ritchie
BACKGROUND: More than half of persons living with HIV (PLWH) in the United States are insufficiently engaged in HIV primary care and not taking antiretroviral therapy (ART), mainly African Americans/Blacks and Hispanics. In the proposed project, a potent and innovative research methodology, the multiphase optimization strategy (MOST), will be employed to develop a highly efficacious, efficient, scalable, and cost-effective intervention to increase engagement along the HIV care continuum...
May 4, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28471841/a-flow-based-model-of-the-hiv-care-continuum-in-the-united-states
#20
Gregg S Gonsalves, A David Paltiel, Paul D Cleary, Michael John Gill, Mari M Kitahata, Peter F Rebeiro, Michael J Silverberg, Michael Horberg, Alison G Abraham, Keri N Althoff, Richard Moore, Ronald J Bosch, H Irene Hall, Edward H Kaplan
BACKGROUND: Understanding the flow of patients through the continuum of HIV care is critical to determine how best to intervene so that the proportion of HIV-infected persons who are on antiretroviral treatment and virally suppressed is as large as possible. METHODS: Using immunological and virological data from the Centers for Disease Control and Prevention and the North American AIDS Cohort Collaboration on Research and Design from 2009-2012, we estimated the distribution of time spent in and dropout probability from each stage in the continuum of HIV care...
April 26, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
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