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https://www.readbyqxmd.com/read/29457055/tuberculin-skin-test-conversion-and-primary-progressive-tuberculosis-disease-in-the-first-5-years-of-life-a-birth-cohort-study-from-cape-town-south-africa
#1
Leonardo Martinez, David M le Roux, Whitney Barnett, Attie Stadler, Mark P Nicol, Heather J Zar
Background: Tuberculosis is a leading cause of global childhood mortality. However, the epidemiology and burden of tuberculosis in infancy is not well understood. We aimed to investigate tuberculin skin test conversion and tuberculosis in the Drakenstein Child Health study, a South African birth cohort in a community in which tuberculosis incidence is hyperendemic. Methods: In this prospective birth cohort study, we enrolled pregnant women older than 18 years who were between 20 and 28 weeks' gestation and who were attending antenatal care in a peri-urban, impoverished South African setting...
January 2018: Lancet Child & Adolescent Health
https://www.readbyqxmd.com/read/29455713/age-specific-global-prevalence-of-hepatitis-b-hepatitis-c-hiv-and-tuberculosis-among-incarcerated-people-a-systematic-review
#2
REVIEW
Stuart A Kinner, Kathryn Snow, Andrea L Wirtz, Frederick L Altice, Chris Beyrer, Kate Dolan
PURPOSE: This study aims to compare the global prevalence of hepatitis B, hepatitis C, HIV, and tuberculosis in incarcerated adolescents and young adults (AYAs) and older prisoners. METHODS: This study is a systematic review and meta-analysis of studies reporting the age-specific prevalence of each infection in prisoners. We grouped age-specific prevalence estimates into three overlapping age categories: AYA prisoners (<25 years), older prisoners (≥25 years), and mixed category (spanning age 25 years)...
March 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29453393/adherence-to-antiretroviral-therapy-and-factors-affecting-low-medication-adherence-among-incident-hiv-infected-individuals-during-2009-2016-a-nationwide-study
#3
Jungmee Kim, Eunyoung Lee, Byung-Joo Park, Ji Hwan Bang, Jin Yong Lee
For ideal clinical benefit, human immunodeficiency virus (HIV)-infected individuals should receive continuous medication. This is the first nationwide antiretroviral therapy (ART) adherence study in Asia, where medication monitoring at national level is systemically available. We estimated the ART adherence of incident HIV-infected individuals and investigated factors affecting low medication adherence using the national health insurance (NHI) claims data from 2007 to 2016. Medication possession ratio (MPR) was used to measure medication adherence and risk factors were identified by multivariable logistic regression analysis...
February 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29452838/external-quality-control-program-in-screening-for-infectious-diseases-at-blood-banks-in-mexico
#4
J Manuel Bello-López, Cristina Castañeda-García, Celerino Muñoz-Estrada, Antonio José Machorro-Peréz
INTRODUCTION: Quality control for the detection of infectious markers in blood banks is a necessary activity to ensure the accuracy of donor screening results. Considering that in Mexico blood safety is one of the goals of the National Action Programs, it is essential to evaluate banks through an External Quality Control Program. OBJECTIVE: To analyze one of the evaluations that showed the greatest participation (2014-2/lot46) of banks in the Mexican Republic in the detection of transfusion-transmitted diseases...
January 11, 2018: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/29452366/prevalence-and-incidence-of-anal-and-cervical-high-risk-human-papillomavirus-hpv-types-covered-by-current-hpv-vaccines-among-hiv-infected-women-in-the-study-to-understand-the-natural-history-of-hiv-aids-in-the-era-of-effective-therapy-the-sun-study
#5
Erna Milunka Kojic, Lois Conley, Tim Bush, Susan Cu-Uvin, Elizabeth R Unger, Keith Henry, John Hammer, Gerome Escota, Teresa M Darragh, Joel M Palefsky, John T Brooks, Pragna Patel
Background: Nonavalent (9v) human papilloma virus vaccine targets high-risk (HR)-HPV types 16, 18, 31, 33, 45, 52, 58, and low-risk 6, 11. We examined prevalence, incidence, and clearance of anal and cervical HR-HPV in HIV-infected women. Methods: From 2004-2006, the SUN Study enrolled 167 women from four US cities. Anal and cervical specimens were collected annually for cytology and identification of 37 HPV types; 14 HR include: 9v 16, 18, 31, 33, 45, 52, 58; non-9v 35, 39, 51, 56, 59, 66, 68...
February 14, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29451005/hiv-infection-and-risk-of-postpartum-infection-complications-and-mortality-in-rural-uganda
#6
Lisa M Bebell, Joseph Ngonzi, Mark J Siedner, Winnie R Muyindike, Bosco M Bwana, Laura E Riley, Yap Boum, David R Bangsberg, Ingrid V Bassett
HIV infection may increase risk of postpartum infection and infection-related mortality. We hypothesized that postpartum infection incidence and attributable mortality in Mbarara, Uganda would be higher in HIV-infected than HIV-uninfected women. We performed a prospective cohort study of 4231 women presenting to a regional referral hospital in 2015 for delivery or postpartum care. All febrile or hypothermic women, and a subset of randomly selected normothermic women were followed during hospitalization and with 6-week postpartum phone interviews...
February 16, 2018: AIDS Care
https://www.readbyqxmd.com/read/29446860/development-of-a-clinical-prediction-rule-for-tuberculous-meningitis-in-adults-in-lima-peru
#7
Lely Solari, Alonso Soto, Patrick van der Stuyft
OBJECTIVES: Diagnosis of Tuberculous Meningitis (TM) is a challenge in countries with a high burden of the disease and constrained resources and Clinical Prediction Rules (CPRs) could be of assistance. We aimed at developing a CPR for diagnosis of TM in a Latin American setting with high tuberculosis incidence and a concentrated HIV epidemic. METHODS: We enrolled adult patients with clinical suspicion of TM attending two hospitals in Lima, Peru. We obtained information on potential anamnestic, clinical and laboratory predictive findings that are easy to collect and promptly available...
February 15, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29446249/serological-responses-to-revaccination-against-hbv-in-hiv-positive-patients-born-in-the-era-of-nationwide-neonatal-hbv-vaccination
#8
Yi-Chia Huang, Szu-Min Hsieh, Wang-Huei Sheng, Yu-Shan Huang, Kuan-Yin Lin, Guan-Jhou Chen, Shang-Ping Yang, Wen-Chun Liu, Yi-Ching Su, Hsin-Yun Sun, Chien-Ching Hung, Shan-Chwen Chang
BACKGROUND: Serological responses to revaccination against hepatitis B virus (HBV) are unclear in HIV-positive adults who had undergone neonatal HBV vaccination and whose antibodies against HBV had waned in the era of combination antiretroviral therapy (cART). METHODS: Between 2000 and 2017, 666 HIV-positive men who have sex with men (MSM) who were born after 1986, when nationwide neonatal HBV vaccination program was implemented in Taiwan, were included for analyses...
February 15, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29445773/leveraging-tuberculosis-case-relative-locations-to-enhance-case-detection-and-linkage-to-care-in-swaziland
#9
Marie Brunetti, Sathyanath Rajasekharan, Piluca Ustero, Katherine Ngo, Welile Sikhondze, Buli Mzileni, Anna Mandalakas, Alexander W Kay
Background: In Swaziland, as in many high HIV/TB burden settings, there is not information available regarding the household location of TB cases for identifying areas of increased TB incidence, limiting the development of targeted interventions. Data from "Butimba", a TB REACH active case finding project, was re-analyzed to provide insight into the location of TB cases surrounding Mbabane, Swaziland. Objective: The project aimed to identify geographical areas with high TB burdens to inform active case finding efforts...
2018: Global Health Research and Policy
https://www.readbyqxmd.com/read/29444997/efficacy-of-multicomponent-culturally-tailored-hiv-sti-prevention-interventions-targeting-foreign-female-entertainment-workers-a-quasi-experimental-trial
#10
Raymond B T Lim, Olive N Y Cheung, Bee Choo Tai, Mark I-C Chen, Roy K W Chan, Mee Lian Wong
OBJECTIVES: We assessed the efficacy of a multicomponent culturally tailored HIV/STI prevention intervention programme on consistent condom use and STI incidence among foreign Thai and Vietnamese female entertainment workers (FEWs) in Singapore. METHODS: We conducted a quasi-experimental pretest and post-test intervention trial with a comparison group. We recruited 220 participants (115 Vietnamese and 105 Thai) for the comparison group, followed by the intervention group (same number) from the same sites which were purposively selected after a 3-month interval period...
February 14, 2018: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29444987/cardiovascular-risk-prediction-functions-underestimate-risk-in-hiv-infection
#11
Virginia A Triant, Jeremiah Perez, Susan Regan, Joseph M Massaro, James B Meigs, Steven K Grinspoon, Ralph B D'Agostino
Background -Cardiovascular disease (CVD) risk is elevated in HIV-infected individuals, with contributions from both traditional and non-traditional risk factors. The accuracy of established CVD risk prediction functions in HIV is uncertain. We sought to assess the performance of three established CVD risk prediction functions in a longitudinal cohort of HIV-infected men. Methods -Framingham Heart Study (Framingham) functions for hard coronary heart disease (Framingham CHD) and atherosclerotic CVD (Framingham ASCVD) and the American College of Cardiology/American Heart Association (ACC/AHA ASCVD) function were applied to the Partners HIV cohort...
February 14, 2018: Circulation
https://www.readbyqxmd.com/read/29440761/intimate-partner-violence-correlates-with-a-higher-hiv-incidence-among-msm-a-12-month-prospective-cohort-study-in-shenyang-china
#12
Hong-Yi Wang, Ning Wang, Zhen-Xing Chu, Jing Zhang, Xiang Mao, Wen-Qing Geng, Yong-Jun Jiang, Hong Shang, Jun-Jie Xu
Intimate partner violence (IPV) and HIV are highly prevalent worldwide among MSM. However, the association between IPV and HIV seroconversion is virtually unknown. This 12-month prospective cohort study was conducted among MSM in Shenyang, China to explore the causality between IPV and the incidence of HIV. Adjusted Hazard Ratios (aHRs) of HIV acquisition were derived from a multivariate time-dependent Cox model and applied to calculate population attributable fractions (PAFs). Among 476 HIV-negative MSM subjects, 89(18...
February 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29439188/incidence-and-risk-factors-for-relapses-in-hiv-associated-non-hodgkin-lymphoma-as-observed-in-the-german-hiv-related-lymphoma-cohort-study
#13
Philipp Schommers, Daniel Gillor, Marcus Hentrich, Christoph Wyen, Timo Wolf, Mark Oette, Alexander Zoufaly, Jan-Christian Wasmuth, Johannes R Bogner, Marcus Müller, Stefan Esser, Alisa Schleicher, Bjöern Jensen, Albrecht Stoehr, Georg Behrens, Alexander Schultze, Jan Siehl, Jan Thoden, Ninon Taylor, Christian Hoffmann
Outcome of HIV-infected patients with AIDS-related lymphomas has improved during recent years. However, data on incidence, risk factors, and outcome of relapses in AIDS-related lymphomas after achieving complete remission are still limited. This prospective observational multicenter study includes HIV-infected patients with biopsy- or cytology proven malignant lymphomas since 2005. Data on HIV infection and lymphoma characteristics, treatment and outcome were recorded. For this analysis, AIDS-related lymphomas patients in complete remission were analyzed in terms of their relapse-free survival and potential risk factors for relapses...
February 8, 2018: Haematologica
https://www.readbyqxmd.com/read/29438560/hiite-hiv-1-incidence-and-infection-time-estimator
#14
Sung Yong Park, Tanzy M T Love, Shivankur Kapoor, Ha Youn Lee, John Hancock
Motivation: Around 2.1 million new HIV-1 infections were reported in 2015, alerting that the HIV-1 epidemic remains a significant global health challenge. Precise incidence assessment strengthens epidemic monitoring efforts and guides strategy optimization for prevention programs. Estimating the onset time of HIV-1 infection can facilitate optimal clinical management and identify key populations largely responsible for epidemic spread and thereby infer HIV-1 transmission chains. Our goal is to develop a genomic assay estimating the incidence and infection time in a single cross-sectional survey setting...
February 9, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29438195/incidence-of-new-hepatitis-c-virus-infection-is-still-increasing-in-french-msm-living-with-hiv
#15
Pierre Pradat, Thomas Huleux, François Raffi, Pierre Delobel, Marc-Antoine Valantin, Isabelle Poizot-Martin, Pascal Pugliese, Jacques Reynes, David Rey, Bruno Hoen, André Cabie, Firouzé Bani-Sadr, Antoine Cheret, Claudine Duvivier, Christine Jacomet, Anne Fresard, Laurent Hustache-Mathieu, Laurent Cotte
OBJECTIVE: High hepatitis C virus (HCV) treatment uptake combined with effective direct-acting antiviral-based regimens resulted in a dramatic decline of HCV infection in French people living with HIV (PLWH). We assessed the yearly incidence of new HCV infection in PLWH enrolled in the large French Dat'AIDS cohort from 2012 to 2016 with a specific focus on MSM. METHODS: The incidence of new HCV infection was determined yearly in HCV-negative PLWH with serological follow-up during 2012-2016...
February 12, 2018: AIDS
https://www.readbyqxmd.com/read/29437750/incidence-and-determinants-of-tuberculosis-infection-among-adult-patients-with-hiv-attending-hiv-care-in-north-east-ethiopia-a-retrospective-cohort-study
#16
Ausman Ahmed, Desalew Mekonnen, Atsede M Shiferaw, Fanuel Belayneh, Melaku K Yenit
OBJECTIVE: This study assessed the incidence of tuberculosis (TB) and its predictors among adults living with HIV/AIDS in government health facilities in north-east Ethiopia. SETTING: A 5-year retrospective cohort study was conducted from May to June 2015 on 451 adult HIV/AIDS-infected individuals who enrolled in the HIV care clinics of government health facilities in north-east Ethiopia. PARTICIPANTS: A total of 451 HIV-infected adults who newly enrolled in the adult HIV care clinic from 1 July 2010 with complete information were followed until May 2015...
February 6, 2018: BMJ Open
https://www.readbyqxmd.com/read/29436331/impact-of-adherence-to-antidepressants-on-long-term-prescription-opioid-use-cessation
#17
Jeffrey F Scherrer, Joanne Salas, Mark D Sullivan, Brian K Ahmedani, Laurel A Copeland, Kathleen K Bucholz, Thomas Burroughs, F David Schneider, Patrick J Lustman
BACKGROUND: Depression contributes to persistent opioid analgesic use (OAU). Treating depression may increase opioid cessation. Aims To determine if adherence to antidepressant medications (ADMs) v. non-adherence was associated with opioid cessation in patients with a new depression episode after >90 days of OAU. METHOD: Patients with non-cancer, non-HIV pain (n = 2821), with a new episode of depression following >90 days of OAU, were eligible if they received ≥1 ADM prescription from 2002 to 2012...
February 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29435709/the-prevalence-and-isolated-subtypes-of-bk-polyomavirus-reactivation-among-patients-infected-with-human-immunodeficiency-virus-1-in-southeastern-china
#18
Caiqin Hu, Ying Huang, Juwei Su, Mengyan Wang, Qihui Zhou, Biao Zhu
BK polyomavirus (BKPyV) is an opportunistic infectious pathogen that is associated with hemorrhagic cystitis and nephropathy, mainly in transplant recipients and human immunodeficiency virus 1 (HIV-1) infected patients. However, molecular characterization studies of BKPyV in China are rare. This study was designed to elucidate the prevalence and to determine the main subtypes of BKPyV among HIV-1-infected patients in southeastern China. In addition, the increased incidences for BKPyV reactivation were analyzed...
February 12, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29434450/incidence-of-hepatocellular-carcinoma-in-patients-with-chronic-liver-disease-due-to-hepatitis-b-or-c-and-coinfected-with-the-human-immunodeficiency-virus-a-retrospective-cohort-study
#19
Patrícia Dos Santos Marcon, Cristiane Valle Tovo, Dimas Alexandre Kliemann, Patrícia Fisch, Angelo Alves de Mattos
AIM: To assess the incidence of hepatocellular carcinoma (HCC) in chronic liver disease due to hepatitis B virus (HBV) or hepatitis C virus (HCV) coinfected with human immunodeficiency virus (HIV). METHODS: A retrospective cohort study was performed, including patients with chronic liver disease due to HBV or HCV, with and without HIV coinfection. Patients were selected in the largest tertiary public hospital complex in southern Brazil between January 2007 and June 2014...
February 7, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29426333/contraceptive-use-and-pregnancy-rates-among-women-receiving-antiretroviral-therapy-in-malawi-a-retrospective-cohort-study
#20
Hannock Tweya, Caryl Feldacker, Salem Gugsa, Sam Phiri
BACKGROUND: In 2011, family planning (FP) services were integrated at Martin Preuss Centre (MPC), in urban Lilongwe, Malawi. To date, no previous study evaluated pregnancy rates among HIV-positive women after the integration of FP services into HIV care at the facility. In this study, we investigated whether integration of FP services into HIV clinical care led to increased use of contraceptives and decreased pregnancy rates. METHODS: This was a retrospective cohort analysis of HIV-positive women from 15 to 49 years of age who accessed antiretroviral therapy (ART) services at MPC...
February 9, 2018: Reproductive Health
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