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https://www.readbyqxmd.com/read/28426309/lgbtq-health-surveillance-data%C3%A2-%C3%A2-power
#1
Randall L Sell
Despite decades of research and advocacy, sexual and gender minorities are still not equitably included in health research and surveillance in the United States. In 1990, as I was beginning graduate school, I wrote on a piece of paper "Data = Power." This was my take on ACT UP's (AIDS Coalition to Unleash Power) "Silence = Death." I created this personal motto because I had been working in the late 1980s on evaluations of some of the earliest federally funded HIV/AIDS prevention programs while attending ACT UP's first demonstration at the Food and Drug Administration in 1988 and attending its action to "Storm the NIH" (National Institutes of Health) in 1990...
April 20, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28416258/-description-of-3-cases-of-skin-and-soft-tissue-infections-caused-by-streptococcus-pneumoniae
#2
Mónica Elisabeth Martínez, Sandra Liliana Grenón, Oscar Herminio López, Lorena Beatriz Leguizamón, Marta Eugenia Mollerach, Martha Helena von Specht
The role of Streptococcus pneumoniae as a causative agent of skin and soft tissue infections (SSTI) is unusual and its clinical interpretation is difficult. We describe here three cases of SSTI due to S. pneumoniae in patients admitted to the Provincial Pediatric Hospital of Misiones, Argentina that were detected during 10 years of invasive disease (ID) surveillance documented in 2010, 2011 and 2015. These cases involved two girls aged 8 and 7 months old, and a two-year-old male child with diagnoses of gluteal abscess, preseptal cellulites and pyoderma respectively...
April 14, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/28414260/retention-in-hiv-care-and-viral-suppression-individual-and-neighborhood-level-predictors-of-racial-ethnic-differences-florida-2015
#3
Diana M Sheehan, Kristopher P Fennie, Daniel E Mauck, Lorene M Maddox, Spencer Lieb, Mary Jo Trepka
The objective of this study was to estimate racial/ethnic differences in retention in HIV care and viral suppression and to identify related individual and neighborhood determinants. Florida HIV surveillance records of cases aged ≥13 years diagnosed during the years 2000-2014 were analyzed. Retention in care was defined as evidence of ≥2 or more laboratory tests, receipts of prescription, or clinical visits at least 3 months apart during 2015. Viral load suppression was defined as a viral load of <200 copies/mL for the last test in 2015...
April 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28411873/-survey-adaptation-for-bio-behavioural-surveillance-of-hiv-in-chilean-female-sex-workers
#4
Bielka Carvajal, Valeria Stuardo, José Manuel Manríquez, Julieta Belmar, Cinta Folch
OBJECTIVE: To adapt a behavioural questionnaire for second-generation HIV/AIDS surveillance in female sex workers (FSWs) in the Metropolitan Region, Chile. METHODS: Qualitative study of instruments validation. A Spanish instrument adapted in Catalonia was validated through a translation and back-translation of the original version. The content validity was determined through a modified Delphi method, via FSW and HIV experts representing community, political and institutional levels...
April 12, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28411524/the-network-structure-of-sex-partner-meeting-places-reported-by-hiv-infected-msm-opportunities-for-hiv-targeted-control
#5
Meredith Brantley, Christina Schumacher, Jamie Perin, Amelia Greiner Safi, Jonathan M Ellen, Ravikiran Muvva, Patrick Chaulk, Jacky M Jennings
Baltimore, Maryland ranks among U.S. cities with the highest incidence of HIV infection among men who have sex with men (MSM). HIV screening at sex partner meeting places or venues frequented by MSM with new diagnoses and/or high HIV viral load may reduce transmission by identifying and linking infected individuals to care. We investigated venue-based clustering of newly diagnosed MSM to identify high HIV transmission venues. HIV surveillance data from MSM diagnosed between October 2012-June 2014 and reporting ≥1 sex partner meeting place were examined...
April 7, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28406271/the-relationship-between-higher-social-trust-and-lower-late-hiv-diagnosis-and-mortality-differs-by-race-ethnicity-results-from-a-state-level-analysis
#6
Yusuf Ransome, Ashley Batson, Sandro Galea, Ichiro Kawachi, Denis Nash, Kenneth H Mayer
INTRODUCTION: Black men who have sex with men (MSM) continue to suffer a disproportionate burden of new HIV diagnoses and mortality. To better understand some of the reasons for these profound disparities, we examined whether the association between social trust and late HIV diagnosis and mortality differed by race/ethnicity, and investigated potential indirect effects of any observed differences. METHODS: We performed generalized structural equation modelling to assess main and interaction associations between trust among one's neighbours in 2009 (i...
April 6, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28401493/characterization-of-stevens-johnson-syndrome-and-toxic-epidermal-necrolysis-among-patients-admitted-to-kenyatta-national-hospital-a-retrospective-cross-sectional-study
#7
Kenneth Irungu, David Nyamu, Sylvia Opanga
BACKGROUND: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous reactions. There is scant literature on the characteristics and causes of these conditions in Kenyatta National Hospital. OBJECTIVE: The aim of this study was to determine the prevalence, risk factors, and etiologies of SJS/TEN among patients admitted to Kenyatta National Hospital. METHODS: A retrospective cross-sectional study was done to find the characteristics and causes of severe cutaneous reactions among patients admitted to Kenyatta National Hospital...
April 11, 2017: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/28400540/cd56-bright-nk-il-7r%C3%AE-expression-negatively-associates-with-hcv-level-and-il-7-induced-nk-function-is-impaired-during-hcv-and-hiv-infections
#8
Chelsey J Judge, Lenche Kostadinova, Kenneth E Sherman, Adeel A Butt, Yngve Falck-Ytter, Nicholas T Funderburg, Alan L Landay, Michael M Lederman, Scott F Sieg, Johan K Sandberg, Donald D Anthony
Several lines of evidence support the concept that NK cells play an important role in control of hepatitis C virus (HCV) infection via cytokine secretion and cytotoxicity. IL-7 is a homeostatic cytokine with a role in T cell development, activation, proliferation, and cytokine secretion. The IL-7Rα chain [cluster of differentiation (CD)127] is expressed on NK cells, with greatest abundance on the CD56(bright)CD16(dim/-) (CD56(bright)) subset. Here, we measured CD127 expression on CD56(bright), CD56(dim)CD16(+) (CD56(dim)), or CD56(neg)CD16(+) (CD56(neg)) NK cell subsets of 25 uninfected donors (UD); 34 chronic HCV-infected, treatment-naïve; 25 HIV-infected, virally suppressed on antiretroviral therapy (ART); and 42 HCV-HIV-coinfected subjects on ART...
April 11, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28398957/association-of-hiv-diagnosis-rates-and-laws-criminalizing-hiv-exposure-in-the-united-states
#9
Patricia Sweeney, Simone C Gray, David W Purcell, Jenny Sewell, Aruna Surendera Babu, Brett A Tarver, Joseph Prejean, Jonathan Mermin
OBJECTIVE: To assess whether state criminal exposure laws are associated with HIV and stage 3 (AIDS) diagnosis rates in the United States. DESIGN: We assessed the relationship between HIV and stage 3 (AIDS) diagnosis data from the National HIV Surveillance System and the presence of a state criminal exposure law as identified through WestlawNext by using generalized estimating equations. METHODS: We limited analysis to persons aged ≥13 years with diagnosed HIV infection or AIDS reported to the National HIV Surveillance System of the Centers for Disease Control and Prevention...
April 10, 2017: AIDS
https://www.readbyqxmd.com/read/28398778/sustained-reduction-in-hiv-diagnoses-in-massachusetts-2000-2014
#10
Kevin Cranston, Betsey John, H Dawn Fukuda, Liisa M Randall, Jonathan Mermin, Kenneth H Mayer, Alfred DeMaria
OBJECTIVES: To describe secular trends in reported HIV diagnoses in Massachusetts concurrent with treatment access expansion. METHODS: We characterized cases of HIV infection reported to the Massachusetts HIV/AIDS Surveillance Program between 2000 and 2014 by sex, age, race/ethnicity, and exposure mode. We used Poisson regression to test the statistical significance of trends in diagnoses. RESULTS: Between 2000 and 2014, annual new HIV infections diagnosed in Massachusetts decreased by 47% (P < ...
May 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28398773/genetic-characterization-of-a-unique-recombinant-strain-identified-in-yunnan-with-genome-comprised-of-b-and-c
#11
Xiaolin Wang, Min Zhang, Jianjian Li, Tianyi Li, Changrong Sun, Hanping Li, Yongjian Liu, Siyang Liu, Daomin Zhuang, Zuoyi Bao, Jingwan Han, Jingyun Li, Lin Li
Since the first identification of HIV-1 outbreak in Dehong, Yunnan province has been the epidemic center of HIV in China. Due to the special geographic location and the frequent population mobility, Yunnan province contained complex HIV subtype distribution. Many new CRFs and URFs have been found in recently years. In this study, a unique HIV-1 recombinant strain (URF) genome (YN10134) was characterized from an HIV-positive female in Yunnan, China. This virus genome had a complex intersubtype recombinant structure with 8 breakpoints, composed of subtype B and subtype C...
February 10, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28395528/projected-demographic-composition-of-the-united-states-population-of-people-living-with-diagnosed-hiv
#12
Julia E Hood, Matthew R Golden, James P Hughes, Steven M Goodreau, Azfar-E-Alam Siddiqi, Susan E Buskin, Stephen E Hawes
The transformation of HIV from a fatal disease to lifelong disease has resulted in an HIV-infected population that is growing and aging, placing new and increasing demands on public programs and health services. We used National HIV Surveillance System and US census data to project the demographic composition of the population of people living with diagnosed HIV (PLWDH) in the United States through 2045. The input parameters for the projections include: (1) census projections, (2) number of people with an existing HIV diagnosis in 2013, (3) number of new HIV diagnoses in 2013, and (4) death rate within the PLWDH population in 2013...
April 10, 2017: AIDS Care
https://www.readbyqxmd.com/read/28393756/norovirus-epidemiology-in-south-african-children-5-years-hospitalised-for-diarrhoeal-illness-between-2009-and-2013
#13
N A Page, M J Groome, S Nadan, R Netshikweta, K H Keddy, B Poonsamy, J Moyes, S Walaza, K Kahn, S A Madhi, M B Taylor, J Mans, C Cohen
Public health interest in norovirus (NoV) has increased in recent years following improved diagnostics, global burden estimates and the development of NoV vaccine candidates. This study aimed to describe the detection rate, clinical characteristics and environmental features associated with NoV detection in hospitalized children <5 years with diarrhoea in South Africa (SA). Between 2009 and 2013, prospective diarrhoeal surveillance was conducted at four sites in SA. Stool specimens were collected and screened for NoVs and other enteric pathogens using molecular and serological assays...
April 10, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28393613/original-title-hiv-infection-and-unawareness-among-men-who-have-sex-with-men-in-puerto-rico-data-from-the-national-hiv-behavioral-surveillance-system-2011-2014
#14
Sandra Miranda de León, Carola T Sánchez-Díaz, Mark Machin-Rivera, Ileska M Valencia-Torres, Yadira Rolón, Vivian Colón-López
BACKGROUND: Unawareness of HIV infection is a public health challenge that needs to be addressed, particularly in the case of men who have sex with men (MSM), since recent data are reporting increasing rates of HIV in this population in Puerto Rico. OBJECTIVES: We examined differences in the prevalence of HIV infection and unawareness among MSM in 2011 and 2014 using data from the National HIV Behavioral Surveillance System, 2011 and 2014. METHODS: Bivariate analyses was used to compare demographical and behavioral characteristics in both cycles (2011 and 2014)...
April 10, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28383390/high-prevalence-of-abacavir-associated-l74v-i-mutations-in-kenyan-children-failing-antiretroviral-therapy
#15
Eric J Dziuban, Joshua DeVos, Bernadette Ngeno, Evelyn Ngugi, Guoqing Zhang, Jennifer Sabatier, Nick Wagar, Karidia Diallo, Lucy Nganga, Abraham Katana, Chunfu Yang, Emilia D Rivadeneira, Irene Mukui, Francesca Odhiambo, Robert Redfield, Elliot Raizes
A survey of 461 HIV-infected Kenyan children receiving antiretroviral therapy found 143 (31%) failing virologically. Drug resistance mutations were found in 121; 37 had L74V/I mutations, with 95% receiving abacavir-containing regimens. L74V/I was associated with current abacavir usage (p=0.0001). L74V/I may be more prevalent than previously realized in children failing abacavir-containing regimens, even when time on treatment has been short. Ongoing rigorous pediatric drug resistance surveillance is needed.
April 5, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28381264/hiv-policy-implementation-in-two-health-and-demographic-surveillance-sites-in-uganda-findings-from-a-national-policy-review-health-facility-surveys-and-key-informant-interviews
#16
Ellen McRobie, Alison Wringe, Jessica Nakiyingi-Miiro, Francis Kiweewa, Tom Lutalo, Gertrude Nakigozi, Jim Todd, Jeffrey William Eaton, Basia Zaba, Kathryn Church
BACKGROUND: Successful HIV testing, care and treatment policy implementation is essential for realising the reductions in morbidity and mortality those policies are designed to target. While adoption of new HIV policies is rapid, less is known about the facility-level implementation of new policies and the factors influencing this. METHODS: We assessed implementation of national policies about HIV testing, treatment and retention at health facilities serving two health and demographic surveillance sites (HDSS) (10 in Kyamulibwa, 14 in Rakai)...
April 5, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28376825/antiretroviral-therapy-supply-chain-quality-control-and-assurance-in-improving-people-living-with-hiv-therapeutic-outcomes-in-cameroon
#17
M P Ngogang Djobet, David Singhe, Julienne Lohoue, Christopher Kuaban, Jeanne Ngogang, Ernest Tambo
BACKGROUND: Evaluation of medication efficacy and safety is an essential guarantee to successful therapeutic outcome in public health practices. However, larger distribution chain supply in developing countries such as Cameroon is often challenged by counterfeit drugs, poor manufacturing, storage and degradation leading to health and patient adverse consequences. Yet, access to supply chain management in strengthening ARVs quality assurance and outcomes remains poorly documented. More than 53,000 patients have been enrolled on free ARVs medications, but little is documented on quality assurance and validity of safety for affected populations along the supply chain management since 2008...
April 4, 2017: AIDS Research and Therapy
https://www.readbyqxmd.com/read/28376085/status-and-methodology-of-publicly-available-national-hiv-care-continua-and-90-90-90-targets-a-systematic-review
#18
Reuben Granich, Somya Gupta, Irene Hall, John Aberle-Grasse, Shannon Hader, Jonathan Mermin
BACKGROUND: In 2014, the Joint United Nations Program on HIV/AIDS (UNAIDS) issued treatment goals for human immunodeficiency virus (HIV). The 90-90-90 target specifies that by 2020, 90% of individuals living with HIV will know their HIV status, 90% of people with diagnosed HIV infection will receive antiretroviral treatment (ART), and 90% of those taking ART will be virally suppressed. Consistent methods and routine reporting in the public domain will be necessary for tracking progress towards the 90-90-90 target...
April 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28369283/the-hiv-continuum-of-care-in-european-union-countries-in-2013-data-and-challenges
#19
Annabelle Gourlay, Teymur Noori, Anastasia Pharris, Maria Axelsson, Dominique Costagliola, Susan Cowan, Sara Croxford, Antonella d'Arminio Monforte, Julia Del Amo, Valerie Delpech, Asunción Díaz, Enrico Girardi, Barbara Gunsenheimer-Bartmeyer, Victoria Hernando, Sophie Jose, Gisela Leierer, Georgios Nikolopoulos, Niels Obel, Eline Op de Coul, Dimitra Paraskeva, Peter Reiss, Caroline Sabin, André Sasse, Daniela Schmid, Anders Sonnerborg, Alexander Spina, Barbara Suligoi, Virginie Supervie, Giota Touloumi, Dominique Van Beckhoven, Ard van Sighem, Georgia Vourli, Robert Zangerle, Kholoud Porter
Background: UNAIDS has set a 90-90-90 target to curb the HIV epidemic by 2020, but methods used to assess whether countries have reached this target are not standardised, hindering comparisons. Methods: Through a collaboration formed by the European Centre for Disease Prevention and Control (ECDC) with European HIV cohorts and surveillance agencies, we constructed a standardised, four-stage continuum of HIV care for 11 European Union (EU) countries for 2013. Stages were defined as: 1) number of people living with HIV (PLHIV) in the country by end of 2013; 2) proportion of stage 1 ever diagnosed; 3) proportion of stage 2 ever initiated ART; and 4) proportion of stage 3 who became virally-suppressed (≤200 copies/mL)...
March 20, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28368493/updated-data-on-linkage-to-human-immunodeficiency-virus-care-and-antiretroviral-treatment-among-men-who-have-sex-with-men-20-cities-united-states
#20
Brooke E Hoots, Teresa J Finlayson, Cyprian Wejnert, Gabriela Paz-Bailey
We examined differences in prevalence of linkage to care and antiretroviral (ARV) treatment among human immunodeficiency virus (HIV)-positive men who have sex with men (MSM) between 2008 and 2014 in National HIV Behavioral Surveillance. Prevalence of linkage to care increased from 79% in 2008 to 87% in 2014 (prevalence ratio [PR], 1.05; 95% confidence interval [CI], 1.03-1.07). ARV treatment increased from 69% in 2008 to 88% in 2014 (adjusted PR, 1.15; 95% CI, 1.12-1.18). Despite these increases, a large disparity in ARV treatment between white and black MSM remains...
March 29, 2017: Journal of Infectious Diseases
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