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https://www.readbyqxmd.com/read/29045912/the-lived-experience-of-first-year-undergraduate-student-nurses-a-hermeneutic-phenomenological-study
#1
Debra J Porteous, Alison Machin
INTRODUCTION: This study gives insight into the experiences and perceptions of one group of undergraduate nursing students as they make the transition into Higher Education and the nursing profession, during the first year, of their three-year programme. Research has shown that first year undergraduate experience is complex and challenging for any student. For undergraduate nursing students, the process of achieving additional professional practice competencies required for United Kingdom nursing registration adds additional responsibility and potentially, more pressure...
October 3, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/29045348/choice-of-endoscopic-procedure-in-children-with-clinically-suspected-gastrointestinal-graft-versus-host-disease
#2
Thomas Mårtensson, Attila Szakos, Karin Mellgren, Jacek Toporski, Johan Arvidson, Thomas H Casswall, Britt Gustafsson
OBJECTIVES: Gastrointestinal graft-versus-host disease (GI-GVHD) is a potentially life-threatening complication after hematopoietic stem cell transplantation. Symptoms indicating GI-GVHD motivates endoscopy with biopsy sampling and histopathological confirmation. However, optimal extent of endoscopy in children is presently unknown. Therefore, we aimed to evaluate if biopsies from the rectosigmoid area versus the rest of the colon/ileocolon with or without biopsies from simultaneous upper endoscopy, were equally reliable for detection of GI-GVHD and relevant differential diagnoses...
October 17, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29045194/testing-an-aac-system-that-transforms-pictograms-into-natural-language-with-persons-with-cerebral-palsy
#3
Joan Pahisa-Solé, Jordi Herrera-Joancomartí
In this paper, we describe a compansion system that transforms the telegraphic language that comes from the use of pictogram-based Augmentative and Alternative Communication (AAC) into natural language. The system was tested with 4 participants with severe cerebral palsy and ranging degrees of linguistic competence and intellectual disabilities. Participants had used pictogram-based AAC at least for the past 30 years each and presented a stable linguistic profile. During tests, which consisted in a total of 40 sessions, participants were able to learn new linguistic skills, such as the use of basic verb tenses, while using the compansion system, which proved a source of motivation...
October 18, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/29045151/dynamic-blue-light-inducible-t7-rna-polymerases-opto-t7rnaps-for-precise-spatiotemporal-gene-expression-control
#4
Armin Baumschlager, Stephanie K Aoki, Mustafa Khammash
Light has emerged as a control input for biological systems due to its precise spatiotemporal resolution. The limited toolset for light control in bacteria motivated us to develop a light-inducible transcription system that is independent from cellular regulation through the use of an orthogonal RNA polymerase. Here, we present our engineered blue light-responsive T7 RNA polymerases (Opto-T7RNAPs) that show properties such as low leakiness of gene expression in the dark state, high expression strength when induced with blue light, and an inducible range of more than 300-fold...
October 18, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/29044907/barriers-and-facilitators-for-health-professionals-referring-aboriginal-and-torres-strait-islander-tobacco-smokers-to-the-quitline
#5
Kimberley Martin, Joanne Dono, Nathan Rigney, Joanne Rayner, Alana Sparrow, Caroline Miller, Andrea Mckivett, Kerin O'Dea, David Roder, Jacqueline Bowden
OBJECTIVE: To examine the barriers and facilitators among health professionals to providing referrals to Quitline for Aboriginal and Torres Strait Islander clients who smoke. METHODS: A brief online survey, based on the Theoretical Domains Framework, was completed by 34 health professionals who work with Aboriginal and Torres Strait Islander people in South Australia and the Northern Territory. RESULTS: Respondents who frequently made referrals had higher domain scores than less frequent referrers for 'Skills and knowledge' (M=4...
October 18, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/29044867/effect-of-one-time-brief-additional-counseling-on-periodic-health-examination-for-40-and-66-year-olds-2-year-follow-up-of-101%C3%A2-260-participants
#6
Ki Young Son, Dong Wook Shin, Hyung-Kook Yang, Jae Moon Yun, So Hyun Chun, Jong-Koo Lee, Be Long Cho
AIM: The aim of the present study was to evaluate whether the effect of one-time brief additional counseling in periodic health examinations (PHE) through the National Screening Program for the Translational Ages in Korea is sustained after 2 years. METHODS: We collected data from National Screening Program for the Translational Ages participants in 2007 and 2008. To evaluate behavior change after 2 years, we collected the participants' health behavior data 2 years later (2009 and 2010)...
October 18, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29044802/differential-and-complementary-roles-of-medial-and-lateral-septum-in-the-orchestration-of-limbic-oscillations-and-signal-integration
#7
Marian Tsanov
Anatomical differences between the medial and lateral septum have associated these nuclei with dissimilar functional roles and behaviors. While the medial septum has been implicated, predominantly, in theta rhythm generation along the septo-hippocampal axis, the lateral septum has mainly been investigated in the context of septo-hypothalamic dialogue. Recent advances suggest that medial and lateral septum are more closely functionally-related than previously appreciated. Here, we explore the hypothesis that the medial septum mediates ascending septo-hippocampal theta propagation, while the lateral septum processes a descending hippocampo-septal and septo-hypothalamic reinforcement signal that mediates navigation during motivated behavior...
October 17, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29044780/-hot-versus-cold-behavioral-cognitive-styles-motivational-dopaminergic-versus-cognitive-cholinergic-processing-of-a-pavlovian-cocaine-cue-in-sign-and-goal-tracking-rats
#8
Kyle K Pitchers, Louisa F Kane, Youngsoo Kim, Terry E Robinson, Martin Sarter
Discrete Pavlovian reward cues acquire more potent incentive motivational properties (incentive salience), in some animals (sign-trackers; STs) compared to others (goal trackers; GTs). Conversely, GTs appear to be better than STs in processing more complex contextual cues, perhaps reflecting their relatively greater bias for goal-directed cue processing. Here we investigated the activity of two major prefrontal neuromodulatory input systems, dopamine (DA) and acetylcholine (ACh), in response to a discrete Pavlovian cue that was previously paired with cocaine administration in STs and GTs...
October 17, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29044733/shyness-preference-for-solitude-and-adolescent-internalizing-the-roles-of-maternal-paternal-and-best-friend-support
#9
Matthew G Barstead, Kelly A Smith, Brett Laursen, Cathryn Booth-LaForce, Shakeena King, Kenneth H Rubin
The researchers examined differential outcomes related to two distinct motivations for withdrawal (preference for solitude and shyness) as well as the possibility that support from important others (mothers, fathers, and best friends) attenuate any such links. Adolescents (159 males, 171 females) reported on their motivations to withdraw, internalizing symptoms, and relationship quality in eighth grade, as well as their anxiety and depression in ninth grade. Using structural equation modeling, the authors found that maternal support weakened the association between shyness and internalizing problems; friend support weakened the association between preference for solitude and depression; and friend support strengthened the association between shyness and depression...
October 17, 2017: Journal of Research on Adolescence: the Official Journal of the Society for Research on Adolescence
https://www.readbyqxmd.com/read/29044601/let-s-not-talk-about-sex
#10
Melanie Love, Barry A Farber
This article uses both a case illustration and data from a large-scale survey of outpatient clients (N = 798) to understand the client's perspective about avoiding or being dishonest with his or her therapist about sexual topics. The case study, of a gay young man working with a heterosexual female therapist, explores this client's experience of what happens when it feels impossible to be forthcoming about sex and sexuality. Based on the findings of our study, we note clients' motives for avoiding these intimate yet important areas (e...
November 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29044479/the-strategies-to-reduce-injuries-and-develop-confidence-in-elders-intervention-falls-risk-factor-assessment-and-management-patient-engagement-and-nurse-co-management
#11
David B Reuben, Priscilla Gazarian, Neil Alexander, Katy Araujo, Dorothy Baker, Jonathan F Bean, Chad Boult, Peter Charpentier, Pamela Duncan, Nancy Latham, Rosanne M Leipzig, Lisa M Quintiliani, Thomas Storer, Siobhan McMahon
In response to the epidemic of falls and serious falls-related injuries in older persons, in 2014, the Patient Centered Outcomes Research Institute (PCORI) and the National Institute on Aging funded a pragmatic trial, Strategies to Reduce Injuries and Develop confidence in Elders (STRIDE) to compare the effects of a multifactorial intervention with those of an enhanced usual care intervention. The STRIDE multifactorial intervention consists of five major components that registered nurses deliver in the role of falls care managers, co-managing fall risk in partnership with patients and their primary care providers (PCPs)...
October 17, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29043918/-being-able-to-speak-what-individuals-in-jail-perceived-as-helpful-about-participating-in-alcohol-related-brief-interventions
#12
Mandy D Owens, Megan Kirouac, Kylee Hagler, Lauren N Rowell, Emily C Williams
BACKGROUND: A significant proportion of individuals within the criminal justice system meet criteria for a substance use disorder. Treatments for individuals who are incarcerated with substance use disorders show minimal to no benefit on post-release outcomes, suggesting a need to improve their effectiveness, particularly those that can be delivered in a brief format. The purpose of this study was to describe what individuals in jail with substance use disorders perceived as being helpful about two brief alcohol-focused interventions, which can be used to inform future treatments with this population...
October 18, 2017: Substance Abuse
https://www.readbyqxmd.com/read/29043091/hope-help-for-people-with-money-employment-benefit-or-housing-problems-study-protocol-for-a-randomised-controlled-trial
#13
M C Barnes, A M Haase, A M Bard, J L Donovan, R Davies, S Dursley, J Potokar, N Kapur, K Hawton, R C O'Connor, W Hollingworth, C Metcalfe, D Gunnell
BACKGROUND: Self-harm and suicide increase in times of economic recession. Factors including job loss, austerity measures, financial difficulties and house repossession contribute to the risk. Vulnerable individuals commonly experience difficulties in navigating the benefits system and in accessing the available sources of welfare and debt advice, and this contributes to their distress. Our aim is to determine the feasibility and acceptability of a brief psychosocial intervention (the "HOPE" service) for people presenting to hospital emergency departments (ED) following self-harm or in acute distress because of financial, employment, or welfare (benefit) difficulties...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29042778/motivation-to-change-and-posttreatment-temptation-to-drink-a-multicenter-study-among-alcohol-dependent-patients
#14
Elena Fiabane, Marcella Ottonello, Valeria Zavan, Caterina Pistarini, Ines Giorgi
BACKGROUND: An inpatient 28-day rehabilitation program for alcohol dependence is focused on detoxification, enhancing motivation to change, and coping strategies for the management of emotional distress and temptation to drink. The aims of the present study were to investigate 1) changes over time in motivation to change, anxiety, and depression in individuals undergoing residential rehabilitation treatment for alcohol addiction, and 2) which pretreatment factors are associated with posttreatment temptation to drink...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29042557/mechanocaloric-effects-in-superionic-thin-films-from-atomistic-simulations
#15
Arun K Sagotra, Daniel Errandonea, Claudio Cazorla
Solid-state cooling is an energy-efficient and scalable refrigeration technology that exploits the adiabatic variation of a crystalline order parameter under an external field (electric, magnetic, or mechanic). The mechanocaloric effect bears one of the greatest cooling potentials in terms of energy efficiency owing to its large available latent heat. Here we show that giant mechanocaloric effects occur in thin films of well-known families of fast-ion conductors, namely Li-rich (Li3OCl) and type-I (AgI), an abundant class of materials that routinely are employed in electrochemistry cells...
October 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/29042433/serotonin-decreases-the-gain-of-visual-responses-in-awake-macaque-v1
#16
Lenka Seillier, Corinna Lorenz, Katsuhisa Kawaguchi, Torben Ott, Andreas Nieder, Paria Pourriahi, Hendrikje Nienborg
Serotonin (5HT) is an important neuromodulator in the brain implicated in affective and cognitive functions but its role even for basic cortical processes is controversial. For example, in the mammalian primary visual cortex heterogenous serotonergic modulation has been observed in anesthetized animals. Here, we combined extracellular single unit recordings with iontophoresis in awake animals. We examined the role of serotonin on well-defined tuning properties (orientation, spatial frequency, contrast and size) in the primary visual cortex (V1) of two male macaque monkeys...
October 17, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29042340/mental-and-emotional-self-help-technology-apps-cross-sectional-study-of-theory-technology-and-mental-health-behaviors
#17
Benjamin T Crookston, Joshua H West, P Cougar Hall, Kaitana Martinez Dahle, Thomas L Heaton, Robin N Beck, Chandni Muralidharan
BACKGROUND: Mental and emotional self-help apps have emerged as potential mental illness prevention and treatment tools. The health behavior theory mechanisms by which these apps influence mental health-related behavior change have not been thoroughly examined. OBJECTIVE: The objective of this study was to examine the association between theoretical behavior change mechanisms and use of mental and emotional self-help apps and whether the use of such apps is associated with mental health behaviors...
October 17, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/29042212/morfpred-plus-computational-identification-of-morfs-in-protein-sequences-using-physicochemical-properties-and-hmm-profiles
#18
Ronesh Sharma, Maitsetseg Bayarjargal, Tatsuhiko Tsunoda, Ashwini Patil, Alok Sharma
Motivation Intrinsically Disordered Proteins (IDPs) lack stable tertiary structure and they actively participate in performing various biological functions. These IDPs expose short binding regions called Molecular Recognition Features (MoRFs) that permit interaction with structured protein regions. Upon interaction they undergo a disorder-to-order transition as a result of which their functionality arises. Predicting these MoRFs in disordered protein sequences is a challenging task. Method In this study, we present MoRFpred-plus, an improved predictor over our previous proposed predictor to identify MoRFs in disordered protein sequences...
October 14, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/29042187/exploring-patient-experiences-of-a-pain-management-centre-a-qualitative-study
#19
Manasi M Mittinty, John Lee, Amanda C de C Williams, Natasha Curran
BACKGROUND AND AIMS: To improve care and management of patients with chronic pain it is important to understand patients' experiences of treatment, and of the people and the environment involved. As chronic pain patients often have long relationships with medical clinics and pain management centres, the team and team interactions with the patients could impact the treatment outcome. The aim of this study was to elicit as honest as possible an account of chronic pain patients' experiences associated with their care and feed this information back to the clinical team as motivation for improvement...
October 14, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29041941/disentangling-the-effects-of-a-multiple-behaviour-change-intervention-for-diarrhoea-control-in-zambia-a-theory-based-process-evaluation
#20
Katie Greenland, Jenala Chipungu, Joyce Chilekwa, Roma Chilengi, Val Curtis
BACKGROUND: Diarrhoea is a leading cause of child death in Zambia. As elsewhere, the disease burden could be greatly reduced through caregiver uptake of existing prevention and treatment strategies. We recently reported the results of the Komboni Housewives intervention which tested a novel strategy employing motives including affiliation and disgust to improve caregiver practice of four diarrhoea control behaviours: exclusive breastfeeding; handwashing with soap; and correct preparation and use of oral rehydration salts (ORS) and zinc...
October 17, 2017: Globalization and Health
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