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https://www.readbyqxmd.com/read/29729159/values-of-the-systemic-immunity-in-patients-suffering-from-acne-with-different-clinical-course
#1
Marianna O Dashko, Orysya O Syzon, Ulyana V Fedorova
OBJECTIVE: Introduction: Acne is chronic recurrent dermatosis, one of the essential skin inflammation in the structure of dermatological pathology, especially in young people of working age, often caused by persistent cicatricial changes in the skin, and affecting negatively the psychoemotional state of patients, their quality of life and working capacity. It has been established by today that the pathogenesis acne is complex and multifactorial, and the changes of immune reactivity of the organism play an important role in its clinical course development...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29705755/chemical-peels-for-acne-vulgaris-a-systematic-review-of-randomised-controlled-trials
#2
Xiaomei Chen, Sheng Wang, Ming Yang, Li Li
OBJECTIVE: We evaluated current evidence from randomised controlled trials (RCTs) regarding the effectiveness of chemical peeling for treating acne vulgaris. METHODS: Standard Cochrane methodological procedures were used. We searched MEDLINE, Cochrane Central Register of Controlled Trials and EMBASE via OvidSP through April 2017. Reviewers independently assessed eligibility, risk of bias and extracted data. RESULTS: Twelve RCTs (387 participants) were included...
April 28, 2018: BMJ Open
https://www.readbyqxmd.com/read/29704270/favre-racouchot-syndrome-report-of-a-case-treated-by-plasma-exeresis
#3
E Rossi, A Paganelli, V D Mandel, G Pellacani
Favre-Racouchot disease (FRD), also known as solar comedo, is a disorder of cosmetic concern relatively common in middle-aged adults1 . It is characterized by the presence of multiple open and closed comedones in an actinically-damaged skin, with preferential localization to periorbital and temporal areas. Major risk factors for FRD seem to be chronic UV exposure, cigarette smoking and radiation therapy2,3,4 . Histologically FRD is characterized by significant actinic elastosis and epidermal atrophy5 This article is protected by copyright...
April 28, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29649008/disseminated-granulomatous-perifollicular-dermatosis-with-comedones-a-follicular-variant-of-lichen-nitidus-or-a-new-entity
#4
Gustavo Deza, Fernando Gallardo, Carlos Barranco, Laura Marquès, Ramon M Pujol
The presence of acquired generalized keratotic follicular papules and comedones developing in adulthood constitute an uncommon clinical situation. Although this clinical presentation has been described in several noninflammatory, inflammatory, and neoplastic skin disorders, its association with an exclusive perifollicular epitheliod or granulomatous inflammatory reaction represents an exceedingly rare phenomenon. We report a case of a 57-year-old male patient presenting clinically numerous acquired disseminated follicular papules and comedones, showing isolated perifollicular sarcoid-like granulomatous inflammatory infiltrates at the histological examination...
April 11, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29564872/reducing-the-oral-isotretinoin-skin-side-effects-efficacy-of-8-omega-ceramides-hydrophilic-sugars-5-niacinamide-cream-compound-in-acne-patients
#5
Maria V Cannizzaro, Annunziata Dattola, Virginia Garofalo, Ester Del Duca, Luca Bianchi
BACKGROUND: Acne vulgaris is a chronic inflammatory skin disease that manifests as open and closed comedones as well as inflammatory papules, pustules, and nodules localized on face and trunk. Oral isotretinoin demonstrated to be effective in controlling seborrhea, inflammation, Propionibacterium Acnes hyperproliferation and reducing scarring, nevertheless muco-cutaneous side effects, particularly dryness, itching, bruising are commonly seen in patients under treatment with isotretinoin reducing the compliance to the treatment...
April 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29525066/-diffuse-hypertrichosis-revealing-non-classical-congenital-adrenal-hyperplasia
#6
C Berthin, P Sibilia, J Martins-Hericher, A Donzeau, L Martin
BACKGROUND: Non-classical congenital adrenal hyperplasia (NC-CAH) is a recessive autosomal disease caused by a deficiency of adrenal steroidogenesis enzymes. It must be distinguished from classical CAH, either simple virilising or salt-wasting, diagnosed during the neonatal period and responsible for potentially lethal disorders of sexual differentiation. NC-CAH presents a simpler and less specific clinical picture. Herein, we present two cases comprising twin girls consulting for diffuse hypertrichosis...
April 2018: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29469717/familial-pseudoxanthoma-elasticum-associated-with-multiple-comedones
#7
Melody Maarouf, Victoria R Sharon, Raja K Sivamani, Neha Prakash, T H Bipin, Tracy Davis, Vivian Y Shi
Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder characterized by atypical elastic fibers that causes connective tissue abnormalities of the skin, eyes, and heart, among other organs. The disorder is rare, with a classic presentation of yellow-orange cobblestone-like papules on flexural areas, lax skin, ocular degeneration, and moribund vasculature in multiple organs. There is wide variability in the presentation of the affected organs [1]. We present two sisters with classic cutaneous findings of PXE with the additional unusual findings of numerous open comedones on the neck...
September 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29462223/efficacy-safety-and-tolerability-of-topical-dapsone-gel-7-5-for-treatment-of-acne-vulgaris-by-fitzpatrick-skin-phototype
#8
Susan C Taylor, Fran E Cook-Bolden, Amy McMichael, Jeanine B Downie, David A Rodriguez, Andrew F Alexis, Valerie D Callender, Nancy Alvandi
BACKGROUND: Acne vulgaris (acne) is prevalent in individuals with skin of color, often with more frequent sequelae than in patients with lighter skin color. It is important to determine if there are also differences in response to medications. OBJECTIVE: This study evaluated the efficacy and tolerability of once-daily dapsone gel, 7.5% in patients with acne, stratified by Fitzpatrick skin phototype. METHODS: Data were pooled from 2 identically designed, phase 3, randomized, double-blind, vehicle-controlled studies in patients aged 12 years and older with moderate acne...
February 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29380941/management-of-comedonal-acne-vulgaris-with-fixed-combination-topical-therapy
#9
Michael H Gold, Hilary Baldwin, Tina Lin
BACKGROUND: Acne vulgaris (acne) is the most common skin disease we see in dermatology practice. Clinically, it is characterized by a combination of open and closed comedones (formally referred to as noninflammatory lesions) and inflammatory papules and pustules. Comedonal acne is more typical in young adolescents, but can occur in combination with inflammatory papules and pustules at any time. Topical retinoids have long been advocated for the treatment of comedonal acne. AIMS: Given the increasing recognition of the inflammatory nature of acne and the synergistic benefits seen with fixed combinations we review the latest clinical data to provide guidance on optimal management of comedonal acne...
April 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29380349/acne-and-hidradenitis-suppurativa
#10
REVIEW
A Pink, F Anzengruber, A A Navarini
Acne and hidradenitis suppurativa (HS) both centre on hair follicles. They often occur together as part of the acne tetrad, but are found in distinct localizations. Acne is primarily defined by the presence of comedones and inflammatory lesions. However, in HS the intertriginous localization and chronicity play equally important roles for the diagnosis to the inflammatory lesions. Genetics, bacteria, environmental factors and innate inflammation have all been found to play a role in acne and/or HS. Surprisingly, there is little overlap between the findings so far...
March 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29369333/confocal-microscopy-in-adult-women-with-acne
#11
Louise Muguet Guenot, Morgane Vourc'h Jourdain, Mélanie Saint-Jean, Stéphane Corvec, Aurélie Gaultier, Amir Khammari, Marie Le Moigne, Aurélie Boisrobert, Charlotte Paugam, Brigitte Dréno
BACKGROUND: Acne is an inflammatory disease of the pilosebaceous follicle, affecting 41-54% of adult women, with a particular form that involves the mandible. METHODS: We characterized infundibulum morphology in two groups of adult women using reflectance confocal microscopy. First, we investigated acne visually "healthy zones" on the forehead in 15 adult women with diffuse acne and compared with acne-free controls. We then compared healthy forehead and affected mandibular zone in 15 acne patients with mandibular involvement...
January 25, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29282195/chloracne-in-a-farming-family
#12
Pragya Kushwaha, Harish Kumar, Sandeep Kulkarni, Ashok Ghorpade
An 11-year-old boy presented with a 1-year history of multiple comedonal lesions distributed over his body. The lesions (Figure 1) were densely distributed throughout his body. Ophthalmologic examination revealed hyperpigmented conjunctival mucosae and enlarged meibomian glands (Figure 2). His nails were also hyperpigmented. In addition, he had been coughing and had a fever, each present for a month. Significant laboratory studies included mild anemia (hemoglobin 11.6 gm%) and leukocytosis of 20,800. A chest x-ray was suggestive of interstitial lung disease...
2017: Skinmed
https://www.readbyqxmd.com/read/29211340/treatment-recalcitrant-comedones
#13
Amelie von Köckritz, Arno Rütten, Markus Böhm, Dieter Metze
No abstract text is available yet for this article.
December 6, 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29137071/a-comparative-study-of-biological-and-metabolic-biomarkers-between-healthy-individuals-and-patients-with-acne-vulgaris-a-cross-sectional-study-protocol
#14
COMPARATIVE STUDY
Kyuseok Kim, Injin Ha, Eunok Kim, Kyunglee Kim
Acne is a multifactorial dermatosis, which is influenced not only by hormones but also by the biochemical relationship between them and the pilosebaceous unit. Inflammatory cytokines, chemokines, active oxygen, and zinc are known to be associated with the development of acne. Further, steroid metabolism is known as one of the important factors related to sebum secretion and comedone formation in acne. However, there is a lack of studies comparing these human biomarkers between healthy individuals and patients with acne...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29118526/panfolliculoma-a-clinical-case-report
#15
Roberto Estrada-Castañón, María Elisa Vega-Memije, Juan Carlos Cuevas-González, María de Guadalupe Chávez-López
Panfolliculoma is a benign neoplasm of follicular differentiation, and its morphological characteristics are similar to those of trichoblastoma, but it shows greater follicular differentiation. A 55-year-old female patient, visited for a dermatological consultation, presented comedo-like lesions on the eyelids, which were accompanied by moderate pruritus that spread gradually. On examination, the patient had localized dermatosis on the face, which symmetrically affected both upper eyelids and to a lesser extent the lower eyelids...
October 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/29084194/-diet-in-pathogenesis-of-acne-vulgaris
#16
REVIEW
Katarzyna Ozdarska, Karolina Osucha, Stepan Savitskyi, Jacek Malejczyk, Ryszard Galus
Acne vulgaris is one of the most common dermatologic condition especially among adolescents. Acne is related to excess sebum production by sebaceous glands, inflammation both within and adjacent to the comedones, hyperproliferation of Propionibacterium acnes. Some of investigations show association between acne and diet. Milk increases the level of IGF-1 leading to the synthesis of androgen-mediated increases sebum production. Chocolate predispose to hyperglycemia and insulinemia which aggravate of acne vulgaris...
October 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29024079/the-preadolescent-acne-microbiome-a-prospective-randomized-pilot-study-investigating-characterization-and-effects-of-acne-therapy
#17
Carrie C Coughlin, Shane M Swink, Joseph Horwinski, Georgia Sfyroera, Julia Bugayev, Elizabeth A Grice, Albert C Yan
BACKGROUND/OBJECTIVES: Acne, a common pediatric disease, tends to be more comedonal in preadolescents, whereas older individuals are more likely to have inflammatory lesions in addition to comedones. Thus the microbiome of preadolescents may be different. In this pilot study we aimed to characterize the preadolescent acne microbiome, compare the microbiome in preadolescents with and without acne, and investigate changes in the microbiome after topical treatment with benzoyl peroxide or a retinoid in a small cohort of preadolescents...
November 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28954114/multiple-vulvar-dilated-pores-in-a-postmenopausal-woman
#18
Ge Shi, Wei Li, Ni Liang, Ting-Ting Wang, Ying Zhou, Yi-Ming Fan
Winer's dilated pore is an infrequent appendageal tumor characterized by a giant comedone on the face, neck, and upper trunk in adults. We report a 57-year-old woman who developed multiple asymptomatic black papules on both labia majora. Histopathology showed grouped dilated follicles lined by keratinizing squamous epithelium in the superficial dermis. The superficial lining epithelium and interfollicular epidermis were atrophic, while the deep epithelium showed mild proliferation and melanin pigmentation with a few short projections extending into the surrounding dermis...
July 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28859748/isotretinoin-and-surgical-extraction-for-adult-onset-nevus-comedonicus
#19
Joanna Dong, Robert G Phelps, Jacob Levitt
We present a case of postmenopausal-onset nevus comedonicus in a 58-year-old white woman with no relevant medical history. Two years before presentation, the patient had had a solitary red nodule, measuring 3.8 cm wide, on the mid lateral region of her left thigh. This progressed to a large area, 11.4 cm wide and 14 cm long, of multiple pruritic and painful red nodules, cysts, and deep open comedones extending across the lateral part of the left thigh, with less severe segmental extension to the lateral aspect of the left leg...
2017: Skinmed
https://www.readbyqxmd.com/read/28857716/chronic-cutaneous-lupus-erythematosus-presenting-as-atypical-acneiform-and-comedonal-plaque-case-report-and-literature-review
#20
M L Vieira, E R M C Marques, Y L A Leda, L F Noriega, D L Bet, G A A M Pereira
Introduction Chronic cutaneous lupus erythematosus (CCLE) usually presents as characteristic erythematous patches and infiltrated coin-shaped plaques. However, there are some atypical clinical variants that may mimic other dermatological conditions. Haroon et al. reported in 1972 an unusual presentation of CCLE with hypertrophic follicular scars seen in acne vulgaris. Acneiform presentation is one of the most rarely reported and one of the most confusing, as it resembles a very common inflammatory skin disease...
January 1, 2017: Lupus
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