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Electroconvulsive therapy

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https://www.readbyqxmd.com/read/28431383/protocolized-hyperventilation-enhances-electroconvulsive-therapy
#1
Aida de Arriba-Arnau, Antonia Dalmau, Virginia Soria, Neus Salvat-Pujol, Carmina Ribes, Ana Sánchez-Allueva, José Manuel Menchón, Mikel Urretavizcaya
BACKGROUND: Hyperventilation is recommended in electroconvulsive therapy (ECT) to enhance seizures and to increase patients' safety. However, more evidence is needed regarding its effects and the optimum method of application. METHODS: This prospective study involving 21 subjects compared two procedures, protocolized hyperventilation (PHV) and hyperventilation as usual (HVau), applied to the same patient in two consecutive sessions. Transcutaneous partial pressure of carbon dioxide (TcPCO2) was measured throughout all sessions...
April 13, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28430980/the-relationship-between-symptom-relief-and-psychosocial-functional-improvement-during-acute-electroconvulsive-therapy-for-patients-with-major-depressive-disorder
#2
Ching-Hua Lin, Wei-Cheng Yang
Background: We aimed to compare the degree of symptom relief to psychosocial functional (abbreviated as "functional") improvement and explore the relationships between symptom relief and functional improvement during acute electroconvulsive therapy (ECT) for patients with major depressive disorder (MDD). Methods: MDD inpatients (N=130) requiring ECT were recruited. ECT was generally performed for a maximum of 12 treatments. Symptom severity, using the 17-item Hamilton Depression Rating Scale (HAMD-17), and psychosocial functioning (abbreviated as "functioning"), using the Modified Work and Social Adjustment Scale (MWSAS), were assessed before ECT, after every 3 ECT treatments, and after the final ECT...
April 18, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28430533/new-directions-in-the-rational-design-of-electrical-and-magnetic-seizure-therapies-individualized-low-amplitude-seizure-therapy-ilast-and-magnetic-seizure-therapy-mst
#3
Thomas Radman, Sarah H Lisanby
Electroconvulsive therapy remains a key treatment option for severe cases of depression, but undesirable side-effects continue to limit its use. Innovations in the design of novel seizure therapies seek to improve its risk benefit ratio through enhanced control of the focality of stimulation. The design of seizure therapies with increased spatial precision is motivated by avoiding stimulation of deep brain structures implicated in memory retention, including the hippocampus. The development of two innovations in seizure therapy-individualized low-amplitude seizure therapy (iLAST) and magnetic seizure therapy (MST), are detailed...
April 21, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28424861/s-ketamine-compared-to-etomidate-during-electroconvulsive-therapy-in-major-depression
#4
Maxim Zavorotnyy, Ina Kluge, Kathrin Ahrens, Thomas Wohltmann, Benjamin Köhnlein, Patricia Dietsche, Udo Dannlowski, Tilo Kircher, Carsten Konrad
Objective of the study was to compare two commonly used anesthetic drugs, S-ketamine and etomidate, regarding their influence on seizure characteristics, safety aspects, and outcome of electroconvulsive therapy (ECT) in major depression. Treatment data of 60 patients who underwent a total number of 13 ECTs (median) because of the severe or treatment-resistant major depressive disorder (DSM-IV) were analyzed. Etomidate, mean dosage (SD) = 0.25 (0.04) mg/kg, was used for anesthesia in 29 participants; 31 patients received S-ketamine, mean dosage (SD) = 0...
April 19, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28422805/a-randomized-pilot-study-comparing-ketamine-and-methohexital-anesthesia-for-electroconvulsive-therapy-in-patients-with-depression
#5
Shona L Ray-Griffith, Lou Ann Eads, Xiaotong Han, Kimberly Golden, Zachary N Stowe
OBJECTIVE: This randomized controlled pilot study examines the differences in response to electroconvulsive therapy (ECT) as defined by an improvement of depressive symptoms between ketamine and methohexital as the primary anesthetic agent. Adverse effects and cognitive tolerability were also examined. METHODS: Subjects undergoing ECT for unipolar or bipolar depression were randomized to receive ketamine or methohexital as the anesthetic agent. Primary outcome measure includes the Hamilton rating scale for depression (17-item)...
April 18, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28422271/a-systematic-review-of-left-unilateral-electroconvulsive-therapy
#6
REVIEW
C H Kellner, K G Farber, X R Chen, A Mehrotra, G D N Zipursky
OBJECTIVE: To systematically review the published clinical trials, case series, and case reports on left unilateral (LUL) electrode placement for clinical electroconvulsive therapy (ECT). METHOD: PubMed, Ovid Medline, and the Cochrane Library were searched for articles concerning LUL ECT. Number of patients, efficacy, and cognitive outcomes were extracted from the papers that met our inclusion criteria. RESULTS: A total of 52 articles were included in this review, consisting of 33 clinical trials, seven case series, and 12 case reports...
April 19, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28417028/general-anaesthesia-protocols-for-patients-undergoing-electroconvulsive-therapy-retrospective-analysis-of-504-sessions-over-a-five-year-period-at-a-tertiary-care-hospital-in-oman
#7
Aravind Narayanan, Chandar Lal, Hamed Al-Sinawi
OBJECTIVES: This study aimed to review general anaesthesia protocols for patients undergoing electroconvulsive therapy (ECT) at a tertiary care hospital in Oman, particularly with regards to clinical profile, potential drug interactions and patient outcomes. METHODS: This retrospective study took place at the Sultan Qaboos University Hospital (SQUH), Muscat, Oman. The electronic medical records of patients undergoing ECT at SQUH between January 2010 and December 2014 were reviewed for demographic characteristics and therapy details...
February 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/28412557/electroconvulsive-therapy-changes-the-regional-resting-state-function-measured-by-regional-homogeneity-reho-and-amplitude-of-low-frequency-fluctuations-alff-in-elderly-major-depressive-disorder-patients-an-exploratory-study
#8
Xiao-Ming Kong, Shu-Xian Xu, Yan Sun, Ke-Yong Wang, Chen Wang, Ji Zhang, Jin-Xiang Xia, Li Zhang, Bo-Jian Tan, Xin-Hui Xie
Electroconvulsive therapy (ECT) is the most effective and rapid treatment for severe major depressive disorder (MDD) in elderly patients. The mechanism of ECT is unclear, and studies on ECT in elderly MDD patients by resting-state functional magnetic resonance imaging are rare. Thirteen elderly MDD patients were scanned before and after ECT using a 3.0T MRI scanner. Regional homogeneity (ReHo) and amplitude of low-frequency fluctuations (ALFF) were processed to compare resting-state function before and after treatment...
April 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28406327/key-updates-in-the-clinical-application-of-electroconvulsive-therapy
#9
Richard D Weiner, Irving M Reti
ECT is the oldest and most effective therapy available for the treatment of severe major depression. It is highly effective in individuals with treatment resistance and when a rapid response is required. However, ECT is associated with memory impairment that is the most concerning side-effect of the treatment, substantially contributing to the controversy and stigmatization surrounding this highly effective treatment. There is overwhelming evidence for the efficacy and safety of an acute course of ECT for the treatment of a severe major depressive episode, as reflected by the recent FDA advisory panel recommendation to reclassify ECT devices from Class III to the lower risk category Class II...
April 13, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28398818/neuroleptic-malignant-syndrome-malignant-catatonia-in-child-psychiatry-literature-review-and-a-case-series
#10
Neera Ghaziuddin, Melissa Hendriks, Paresh Patel, Lee E Wachtel, Dirk M Dhossche
OBJECTIVE: To describe the presentation of neuroleptic malignant syndrome (NMS) and malignant catatonia (MC) in children and adolescents. BACKGROUND: NMS and MC are life-threatening, neuropsychiatric syndromes, associated with considerable morbidity and mortality. NMS is diagnosed when there is a recent history of treatment with an antipsychotic (AP) medication, while MC is diagnosed when the symptoms resemble NMS but without a history of exposure to an AP agent...
February 23, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28397635/effects-of-electroconvulsive-therapy-on-amygdala-function-in-major-depression-a-longitudinal-functional-magnetic-resonance-imaging-study
#11
R Redlich, C Bürger, K Dohm, D Grotegerd, N Opel, D Zaremba, S Meinert, K Förster, J Repple, R Schnelle, C Wagenknecht, M Zavorotnyy, W Heindel, H Kugel, M Gerbaulet, J Alferink, V Arolt, P Zwanzger, U Dannlowski
BACKGROUND: Electroconvulsive therapy (ECT) is one of the most effective treatments for severe depression. However, little is known regarding brain functional processes mediating ECT effects. METHOD: In a non-randomized prospective study, functional magnetic resonance imaging data during the automatic processing of subliminally presented emotional faces were obtained twice, about 6 weeks apart, in patients with major depressive disorder (MDD) before and after treatment with ECT (ECT, n = 24)...
April 11, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28385704/adjunctive-ketamine-in-electroconvulsive-therapy-updated-systematic-review-and-meta-analysis
#12
REVIEW
Alexander McGirr, Marcelo T Berlim, David J Bond, Peter Y Chan, Lakshmi N Yatham, Raymond W Lam
BackgroundKetamine has emerged as a novel therapeutic agent for major depressive episodes, spurring interest in its potential to augment electroconvulsive therapy (ECT).AimsWe sought to update our preliminary systematic review and meta-analysis, focusing on randomised controlled trials (RCTs) involving an index course of ECT, and testing the hypothesis that lack of efficacy is due to barbiturate anaesthetic co-administration.MethodWe searched EMBASE, CENTRAL and Medline to identify RCTs examining the efficacy of ketamine during a course of ECT...
April 6, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28384319/correction-antidepressant-and-neurocognitive-effects-of-isoflurane-anesthesia-versus-electroconvulsive-therapy-in-refractory-depression
#13
Howard R Weeks, Scott C Tadler, Kelly W Smith, Eli Iacob, Mikala Saccoman, Andrea T White, Joshua D Landvatter, Gordon J Chelune, Yana Suchy, Elaine Clark, Michael K Cahalan, Lowry Bushnell, Derek Sakata, Alan R Light, Kathleen C Light
[This corrects the article DOI: 10.1371/journal.pone.0069809.].
2017: PloS One
https://www.readbyqxmd.com/read/28383349/co-occurring-catatonia-and-posterior-reversible-encephalopathy-syndrome-responsive-to-electroconvulsive-therapy
#14
Katherine E Klingensmith, Gerard Sanacora, Robert Ostroff
No abstract text is available yet for this article.
April 5, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28383346/electroconvulsive-therapy-in-the-treatment-of-the-blues-taking-a-page-from-the-playbook-of-blues-musicians
#15
W Vaughn McCall, Peter B Rosenquist
No abstract text is available yet for this article.
April 5, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28376941/systematic-evaluation-of-skeletal-fractures-caused-by-induction-of-electroconvulsive-seizures-in-rat-state-a-need-for-attention-and-refinement-of-the-procedure
#16
Maria Ekemohn, Marie Kjær Nielsen, Matilda Grahm, Anders Tingström, Birgitte Kousholt, Gregers Wegener, Cecilie Bay-Richter
OBJECTIVE: Electroconvulsive therapy (ECT) is one of the most efficient treatments for major depression. Electroconvulsive seizures (ECS), the animal model of ECT, is widely used to study both mechanisms of action and adverse effects of ECT. As the treatment itself serves as an instant anaesthetic and anaesthetic agents may affect memory functions and behaviour, ECS is traditionally administered without muscle relaxation and anaesthesia. A major problem of unmodified ECS, which has only been addressed peripherally in the literature, is that some animals sustain spinal fractures and subsequent hind leg paralysis (paraplegia)...
April 5, 2017: Acta Neuropsychiatrica
https://www.readbyqxmd.com/read/28376692/neuroversion-using-electroconvulsive-therapy-as-a-bridge-to-deep-brain-stimulation-implantation
#17
Nolan R Williams, Greg Sahlem, Jaspreet Pannu, Istvan Takacs, Baron Short, Gonzalo Revuelta, Mark S George
Parkinson's disease (PD) is a movement disorder with significant neuropsychiatric comorbidities. Electroconvulsive therapy (ECT) is effective in treating these neuropsychiatric symptoms; however, clinicians are reluctant to use ECT in patients with deep brain stimulation (DBS) implantations for fear of damaging the device, as well as potential cognitive side effects. Right unilateral ultra-brief pulse (RUL UBP) ECT has a more favorable cognitive side-effect profile yet has never been reported in PD patients with DBS implants...
February 2017: Neurocase
https://www.readbyqxmd.com/read/28376409/cognitive-training-to-improve-memory-in-individuals-undergoing-electroconvulsive-therapy-negative-findings
#18
Jimmy Choi, Yuanjia Wang, Tianshu Feng, Joan Prudic
Although electroconvulsive therapy (ECT) remains the most effective treatment for severe depression, some patients report persistent memory problems following ECT that impact their quality of life and their willingness to consent to further ECT. While cognitive training has been shown to improve memory performance in various conditions, this approach has never been applied to help patients regain their memory after ECT. In a double-blind study, we tested the efficacy of a new cognitive training program called Memory Training for ECT (Mem-ECT), specifically designed to target anterograde and retrograde memory that can be compromised following ECT...
March 24, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28373802/is-the-ultimate-treatment-response-predictable-with-early-response-in-major-depressive-episode
#19
Aslı Çiftçi, Halis Ulaş, Ahmet Topuzoğlu, Zeliha Tunca
INTRODUCTION: New evidence suggests that the efficacy of antidepressants occurs within the first weeks of treatment and this early response predicts the later response. The purpose of the present study was to investigate if the partial response in the first week predicts the response at the end of treatment in patients with major depressive disorder who are treated with either antidepressant medication or electroconvulsive therapy. METHODS: Inpatients from Dokuz Eylül University Hospital with a major depressive episode, treated with antidepressant medication (n=52) or electroconvulsive therapy (ECT) (n=48), were recruited for the study...
September 2016: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28367711/improvement-of-cycloid-psychosis-following-electroconvulsive-therapy
#20
Jonas Holm, Ole Brus, Ullvi Båve, Mikael Landen, Johan Lundberg, Pia Nordanskog, Lars von Knorring, Axel Nordenskjöld
BACKGROUND: The treatment of choice for cycloid psychosis has traditionally been electroconvulsive therapy (ECT), but there is a lack of studies on its effectiveness. AIMS: The primary aim of this register study was to determine the rates of remission and response after ECT for cycloid psychosis. The secondary aim was to examine possible predictors of outcome. METHODS: Data were obtained from the National Quality Register for ECT in Sweden...
April 3, 2017: Nordic Journal of Psychiatry
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