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https://www.readbyqxmd.com/read/29667775/views-of-parents-of-children-with-sickle-cell-disease-on-pre-implantation-genetic-diagnosis
#1
Isha Darbari, Jeanne E O'Brien, Steven J Hardy, Barbara Speller-Brown, Lisa Thaniel, Brenda Martin, Deepika S Darbari, Robert S Nickel
Pre-implantation genetic diagnosis (PGD) is an option for parents who have a child with sickle cell disease (SCD) to have another child without SCD. We conducted a survey of 19 parents with at least one child with SCD to investigate views on PGD. Before education, 44% of parents were aware of PGD. All parents rated PGD education as important. All parents considering another child also reported interest in using PGD if insurance covered its costs. Parents who have a child with SCD appear to be interested in PGD and educational tools informing this group about PGD should be developed...
April 18, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29660297/structured-integration-of-family-planning-curriculum-comparative-assessment-of-knowledge-and-skills-among-new-medical-graduates-in-ethiopia
#2
Berhanu G Gebremeskel, Alula M Teklu, Lia T Gebremedhin, Solomon W Beza, Tegbar Yigzaw, Munir K Eshetu, Mengistu H Damtew, Yolanda R Smith
OBJECTIVE: To assess if structured integration of a comprehensive family planning (FP) training into a medical school curriculum improves FP knowledge and skill scores of medical interns. STUDY DESIGN: We compared mean contraception knowledge scores of interns in a medical school with the integrated FP curriculum [intervention school] (n=56) to interns at four conventional medical curriculum schools without structured reinforcement of FP content [control schools] (n=161) in Ethiopia...
April 13, 2018: Contraception
https://www.readbyqxmd.com/read/29659976/a-novel-radiation-shielding-undergarment-using-tungsten-functional-paper-for-patients-with-permanent-prostate-brachytherapy
#3
Masahiro Inada, Hajime Monzen, Kenji Matsumoto, Mikoto Tamura, Takafumi Minami, Kiyoshi Nakamatsu, Yasumasa Nishimura
Tungsten functional paper (TFP) is a paper-based radiation-shielding material, which is lead-free and easy to cut. We developed a radiation protection undergarment using TFP for prostate cancer patients treated with permanent 125I seed implantation (PSI). The aim of this study was to evaluate the shielding ability of the undergarment with respect to household contacts and members of the public. Between October 2016 and April 2017, a total of 10 prostate cancer patients treated with PSI were enrolled in this prospective study...
April 11, 2018: Journal of Radiation Research
https://www.readbyqxmd.com/read/29653440/long-term-outcome-after-dynamic-graciloplasty-for-treatment-of-persistent-fecal-incontinence-in-patients-with-anorectal-malformations
#4
Johan Danielson, Urban Karlbom, Tomas Wester, Wilhelm Graf
PURPOSE:  Dynamic graciloplasty (DGP) has been used to treat severe fecal incontinence since the 1980s. Previous studies have shown an inferior outcome in patients with anorectal malformations (ARMs). Our experience has been that DGP has been appreciated by ARM -patients. The objective of the study was to evaluate the long-term outcome of DGP in our patients with ARM compared with patients with other underlying conditions. MATERIALS AND METHODS:  Twenty-three patients operated with DGP at our institution from 1996 to 2010 were sent validated bowel function and quality of life questionnaires...
April 13, 2018: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29649894/use-of-neural-response-telemetry-for-pediatric-cochlear-implants-current-practice
#5
Galit Almosnino, Samantha Anne, Seth R Schwartz
OBJECTIVES: Evaluate usage trends of neural response telemetry (NRT) in cochlear implant centers across the nation and assess reported benefits of intraoperative NRT for pediatric cochlear implant recipients. STUDY DESIGN: Survey. STUDY PARTICIPANTS: All US cochlear implant centers (n = 110). METHODS: A 15-question multiple-choice survey was distributed electronically to all centers. The survey captured demographic information of all centers, practice patterns surrounding the use of NRT, and the extent to which intraoperative NRT is of benefit...
April 1, 2018: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29649615/fever-related-arrhythmic-events-in-the-multicenter-survey-on-arrhythmic-events-in-brugada-syndrome-sabrus
#6
Yoav Michowitz, Anat Milman, Georgia Sarquella-Brugada, Antoine Andorin, Jean Champagne, Pieter G Postema, Ruben Casado-Arroyo, Eran Leshem, Jimmy Jm Juang, Carla Giustetto, Jacob Tfelt-Hansen, Yanushi D Wijeyeratne, Christian Veltmann, Domenico Corrado, Sung-Hwan Kim, Pietro Delise, Shingo Maeda, Jean-Baptiste Gourraud, Frederic Sacher, Philippe Mabo, Yoshihide Takahashi, Tsukasa Kamakura, Takeshi Aiba, Giulio Conte, Aviram Hochstadt, Yuka Mizusawa, Michael Rahkovich, Elena Arbelo, Zhengrong Huang, Isabelle Denjoy, Carlo Napolitano, Ramon Brugada, Leonardo Calo, Silvia G Priori, Masahiko Takagi, Elijah R Behr, Fiorenzo Gaita, Gan-Xin Yan, Josep Brugada, Antoine Leenhardt, Arthur A M Wilde, Pedro Brugada, Kengo F Kusano, Kenzo Hirao, Gi-Byoung Nam, Vincent Probst, Bernard Belhassen
BACKGROUND: The literature on fever related arrhythmic events (AE) in Brugada syndrome (BrS) is currently limited to few case reports and small series. OBJECTIVE: The current study aims to describe the characteristics of fever-related AE in a large cohort of BrS patients. METHODS: SABRUS is a multicenter study on 678 BrS patients with first AE documented at time of aborted cardiac arrest (ACA) (n=426) or after prophylactic ICD implantation (n=252)...
April 9, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29625970/clinical-course-and-quality-of-life-in-high-risk-patients-with-hypertrophic-cardiomyopathy-and-implantable-cardioverter-defibrillators
#7
Barry J Maron, Susan A Casey, Iacopo Olivotto, Mark V Sherrid, Christopher Semsarian, Camillo Autore, Aisha Ahmed, Giuseppe Boriani, Pietro Francia, Stephen L Winters, Michael Giudici, Anna Koulova, Ross Garberich, Ethan J Rowin, Samuel F Sears, Martin S Maron, Paolo Spirito
BACKGROUND: High-risk patients with hypertrophic cardiomyopathy (HCM) are identified by contemporary risk stratification and effectively treated with implantable cardioverter-defibrillators (ICDs). However, long-term HCM clinical course after ICD therapy for ventricular tachyarrhythmias is incompletely understood. METHODS AND RESULTS: Cohort of 486 high-risk HCM patients with ICDs was assembled from 8 international centers. Clinical course and device interventions were addressed, and survey questionnaires assessed patient anxiety level and psychological well-being related to ICD therapy...
April 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29624499/adaptation-of-cardiovascular-system-stent-implants
#8
Vytautas Ostasevicius, Yahor Tretsyakou-Savich, Mantas Venslauskas, Agne Bertasiene, Vladimir Minchenya, Pavel Chernoglaz
Time-consuming design and manufacturing processes are a serious disadvantage when adapting human cardiovascular implants as they cause unacceptable delays after the decision to intervene surgically has been made. An ideal cardiovascular implant should have a broad range of characteristics such as strength, viscoelasticity and blood compatibility. The present research proposes the sequence of the geometrical adaptation procedures and presents their results. The adaptation starts from the identification of a person's current health status while performing abdominal aortic aneurysm (AAA) imaging, which is a point of departure for the mathematical model of a cardiovascular implant...
April 6, 2018: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/29624081/metal-resurfacing-inlay-implant-for-osteochondral-talar-defects-after-failed-previous-surgery-a-midterm-prospective-follow-up-study
#9
Gwendolyn Vuurberg, Mikel L Reilingh, Christiaan J A van Bergen, Inge C M van Eekeren, Rogier M Gerards, C Niek van Dijk
BACKGROUND: Treatment of osteochondral talar defects (OCDs) after failed previous surgery is challenging. Promising short-term results have been reported with use of a metal resurfacing inlay implant. PURPOSE: To evaluate the midterm clinical effectiveness of the metal implant for OCDs of the medial talar dome after failed previous surgery. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: We prospectively studied all patients who met the inclusion criteria and received a metal resurfacing inlay implant between 2007 and 2014...
April 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29623695/a-case-series-of-patients-who-underwent-laparoscopic-extraperitoneal-radical-prostatectomy-with-the-simultaneous-implant-of-a-penile-prosthesis-focus-on-penile-length-preservation
#10
Nicola Mondaini, Tommaso Cai, Enrico Sarti, Gaia Polloni, Andrea Gavazzi, Duccio Conti, Andrea Cocci, Maarten Albersen, Gianmartin Cito, Riccardo Bartoletti
PURPOSE: There are many grey areas in the field of penile rehabilitation after radical prostatectomy (RP). The preservation of the full dimensions of the penis is an important consideration for improving patients' compliance for the treatment. We present the first case series of patients treated by laparoscopic extraperitoneal RP and simultaneous penile prosthesis implantation (PPI) in order to preserve the full length of the penis and to improve patients' satisfaction. MATERIALS AND METHODS: From June 2013 to June 2014, 10 patients underwent simultaneous PPI (with an AMS InhibiZone prosthesis) and RP...
January 26, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29623590/improvement-of-body-composition-and-quality-of-life-following-intragastric-balloon
#11
Silvia Mansur Reimão, Maria Elizabeth Rossi da Silva, Gabriel Cairo Nunes, Luiz Henrique Mazzonetto Mestieri, Rosa Ferreira Dos Santos, Eduardo Guimarães Hourneaux de Moura
BACKGROUND: The aim is to evaluate the effects of IGB in overweight or class I obese patients, by analyzing body composition and quality of life (QOL). METHODS: Prospective study including patients with BMI 27-34.9 kg/m2. body composition analysis (BCA) was performed before IGB implantation and its removal, after 6 months of treatment. QOL was assessed by the Short Form 36 (SF-36) Health Survey at baseline and after treatment. RESULTS: Forty patients were included in this study, but four were excluded...
April 6, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29615017/clinical-and-radiographic-outcome-of-dynamic-cervical-implant-dci-arthroplasty-for-degenerative-cervical-disc-disease-a-minimal-five-year-follow-up
#12
Lin-Nan Wang, Bo-Wen Hu, Lei Wang, Yue-Ming Song, Xi Yang, Li-Min Liu, Hao Liu
BACKGROUND: To evaluate the mid- to long-term clinical and radiographic outcomes of anterior cervical discectomy and dynamic cervical implant (DCI) arthroplasty for degenerative cervical disc disease. METHODS: From April 2010 to October 2010, 38 patients with single- or double-level cervical disc herniation underwent anterior cervical discectomy and DCI arthroplasty. The clinical results and radiographic outcomes of these 38 patients (42 levels) were retrospectively evaluated...
April 4, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29608491/ready-set-go-how-patients-and-caregivers-are-prepared-for-self-management-of-an-implantable-ventricular-assist-device
#13
Jesus M Casida, Pamela Combs, MaryKay Pavol, Kathleen T Hickey
Since the first use of an implantable ventricular assist device (VAD) nearly 3 decades ago, many VAD Centers in the United States expect patients and caregivers to manage the device and related care following hospital discharge. Despite this customary practice and the rapid advancements in VAD technology, no research data about the patient and caregiver preparations exist for self-management of VAD. This study explored the process of preparing patients and caregivers for VAD care before hospital discharge along with their perceived experiences of the discharge process...
March 28, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29605558/navigated-versus-conventional-total-knee-arthroplasty-a-prospective-study-at-three-years-follow-up
#14
C Martín-Hernández, M Sanz-Sainz, C Revenga-Giertych, D Hernández-Vaquero, J M Fernández-Carreira, J Albareda-Albareda, A Castillo-Palacios, M Ranera-Garcia
OBJECTIVE: Computer-assisted surgery application in total knee arthroplasty (TKA) has shown more accurate implant alignment compared with conventional instrumentation and is associated with more homogeneous alignment results. Although longer implant survival and superior clinical outcomes should be expected from navigated TKA, currently available evidence does not support this hypothesis. The aim of this study was to compare navigated TKA with conventional TKA regarding clinical and radiological outcomes after a 3-year follow-up under the hypothesis that navigated TKA would provide better outcomes than conventional TKA...
March 28, 2018: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/29599096/antithrombotic-therapy-trends-in-non-valvular-atrial-fibrillation-patients-undergoing-percutaneous-coronary-stent-implantation-results-from-a-survey-among-fellows-at-the-japanese-college-of-cardiology
#15
Daisuke Fukamachi, Atsushi Hirayama, Katsumi Miyauchi, Satoshi Yasuda, Hisao Ogawa, Hiroshi Ito, Hiroyuki Daida
BACKGROUND: Antithrombotic therapy with oral anticoagulants (OAC) in patients with atrial fibrillation (AF) after stent implantation, where dual antiplatelet therapy (DAPT) is also recommended, is not established. Antithrombotic therapies prescribed vary widely among cardiologists and may change year by year, according to the accumulation of new evidence. METHODS: A questionnaire-based survey concerning the antithrombotic therapy prescribed for OAC-treated AF patients who underwent stent implantation was conducted from 2014 to 2016...
March 26, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29598886/mapping-existing-hip-and-knee-replacement-registries-in-europe
#16
REVIEW
A Lübbeke, A J Silman, C Barea, D Prieto-Alhambra, A J Carr
The general shortage of evidence regarding benefits and harms of medical devices has been highlighted following the serious safety concerns with metal-on-metal hip replacements and silicone breast implants and was again pointed out in a recent survey of European Health Technology Assessment institutions. In this context the new European medical device regulation will enforce post-marketing surveillance of existing and new implants. The usefulness of registry data as a source of information for medical device real-world clinical performance and safety has been demonstrated...
March 17, 2018: Health Policy
https://www.readbyqxmd.com/read/29595747/postoperative-infection-in-patients-undergoing-posterior-lumbosacral-spinal-surgery-a-pictorial-guide-for-diagnosis-and-early-treatment
#17
Shih-Hao Chen, Wen-Jer Chen, Meng-Huang Wu, Jen-Chung Liao, Chen-Ju Fu
Surgical site infections after posterior spinal surgery may lead to spondylodiscitis, pseudarthrosis, correction loss, adverse neurological sequelae, sepsis, and poor outcomes if not treated immediately. Infection rates vary depending on the type and extent of operative procedures, use of instrumentation, and patients' risk factors. Image evaluation is crucial for early diagnosis and should be complementary to clinical routes, laboratory survey, and treatment timing. Magnetic resonance imaging detects early inflammatory infiltration into the vertebrae and soft tissues, including hyperemic changes of edematous marrow, vertebral endplate, and abscess or phlegmon accumulation around the intervertebral disk, epidural, and paravertebral spaces...
March 27, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29589953/ten-year-results-of-medial-open-wedge-high-tibial-osteotomy-and-chondral-resurfacing-in-severe-medial-osteoarthritis-and-varus-malalignment
#18
Philipp Schuster, Markus Geßlein, Michael Schlumberger, Philipp Mayer, Raul Mayr, Damian Oremek, Sebastian Frank, Martin Schulz-Jahrsdörfer, Jörg Richter
BACKGROUND: High tibial osteotomy (HTO) is a widely used treatment option for medial osteoarthritis and varus malalignment, especially in young patients with early osteoarthritis. Limited outcome data are available for this procedure in severe osteoarthritis, and no long-term data are available using newer implants. PURPOSE: To determine survivorship and functional results of medial open-wedge HTO combined with a chondral resurfacing (CR) procedure (abrasion plus microfracture) in severe medial osteoarthritis (Kellgren-Lawrence grade 3 and 4) and varus malalignment...
March 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29589490/factors-associated-with-health-related-quality-of-life-hip-function-and-health-utility-after-operative-management-of-femoral-neck-fractures
#19
S Sprague, M Bhandari, M J Heetveld, S Liew, T Scott, S Bzovsky, D Heels-Ansdell, Q Zhou, M Swiontkowski, E H Schemitsch
Aims The primary aim of this prognostic study was to identify baseline factors associated with physical health-related quality of life (HRQL) in patients after a femoral neck fracture. The secondary aims were to identify baseline factors associated with mental HRQL, hip function, and health utility. Patients and Methods Patients who were enrolled in the Fixation using Alternative Implants for the Treatment of Hip Fractures (FAITH) trial completed the 12-item Short Form Health Survey (SF-12), Western Ontario and McMaster Universities Arthritis Index, and EuroQol 5-Dimension at regular intervals for 24 months...
March 1, 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29580916/influences-on-intentions-to-place-long-acting-reversible-contraceptives-a-pilot-study-comparing-by-provider-specialty-in-ohio
#20
Charee Thompson, Jane Broecker, Maggie Dade, Kelly Nottingham
STUDY OBJECTIVE: According to the American Academy of Pediatrics (AAP), pediatricians are to counsel and provide LARCs as first-line-of-defense contraceptives because they are the most effective. We wanted to explore positive influences on LARC placement for pediatricians, particularly when compared to providers in other specialties who care for women. DESIGN: Survey methods with data analyzed using analyses of variance and general linear models in statistical software SPSS 24...
March 23, 2018: Journal of Pediatric and Adolescent Gynecology
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