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https://www.readbyqxmd.com/read/27910751/recent-advances-in-pharmacotherapeutic-paradigm-of-mild-to-recalcitrant-atopic-dermatitis
#1
Zahid Hussain, Shariza Sahudin, Hnin Ei Thu, Ahmad Nazrun Shuid, Syed Nasir Abbas Bukhari, Endang Kumolosasi
Atopic dermatitis (AD) is a common, chronic skin inflammatory disorder characterized by perivascular infiltration of immunoglobulin E (IgE), T lymphocytes, and mast cells. The key factors responsible for the pathophysiology of this disease are immunological disorders and defects in epidermal barrier properties. Pruritus, intense itching, psychological stress, deprived physical and mental performance, and sleep disturbance are the hallmark features of this dermatological disorder. Preventive interventions such as educational programs, avoidance of allergens, and exclusive care toward the skin could play a partial role in suppressing the symptoms...
2016: Critical Reviews in Therapeutic Drug Carrier Systems
https://www.readbyqxmd.com/read/27906939/a-new-radiofrequency-ablation-procedure-to-treat-sacroiliac-joint-pain
#2
Jianguo Cheng, See Loong Chen, Nicole Zimmerman, Jarrod E Dalton, Garret LaSalle, Richard Rosenquist
BACKGROUND: Low back pain may arise from disorders of the sacroiliac joint in up to 30% of patients. Radiofrequency ablation (RFA) of the nerves innervating the sacroiliac joint has been shown to be a safe and efficacious strategy. OBJECTIVES: We aimed to develop a new RFA technique to relieve low back pain secondary to sacroiliac joint disorders. STUDY DESIGN: Methodology development with validation through prospective observational non-randomized trial (PONRT)...
November 2016: Pain Physician
https://www.readbyqxmd.com/read/27901408/four-steps-to-eliminate-or-reduce-pain-in-children-caused-by-needles-part-1
#3
Stefan J Friedrichsdorf
Dr Stefan Friedrichsdorf* speaks to Jade Parker, Commissioning Editor: Stefan J Friedrichsdorf, MD, is medical director of the Department of Pain Medicine, Palliative Care and Integrative Medicine at Children's Hospitals and Clinics of Minnesota, Minneapolis/St Paul, MN, USA, home to one of the largest and most comprehensive programs of its kind in the country. The interdisciplinary pain team is devoted to prevent and treat acute, procedural, neuropathic, psycho-social-spiritual, visceral, and chronic/complex pain for all inpatients and outpatients in close collaboration with all pediatric subspecialties at Children's Minnesota...
November 30, 2016: Pain Management
https://www.readbyqxmd.com/read/27886657/receipt-of-addiction-treatment-as-a-consequence-of-a-brief-intervention-for-drug-use-in-primary-care-a-randomized-trial
#4
Theresa W Kim, Judith Bernstein, Debbie M Cheng, Christine Lloyd-Travaglini, Jeffrey H Samet, Tibor P Palfai, Richard Saitz
BACKGROUND AND AIMS: Screening, brief intervention and 'referral to treatment' programs have been widely promoted as US federal policy. Little is known about the efficacy of the RT component (referral to treatment) of brief intervention for motivating patients with unhealthy drug use identified by screening to use addiction treatment. This study aimed to compare receipt of addiction treatment following two types of brief intervention for drug use vs a no-intervention control group among primary care patients screening positive for drug use...
November 25, 2016: Addiction
https://www.readbyqxmd.com/read/27886368/written-information-for-patients-or-parents-of-child-patients-to-reduce-the-use-of-antibiotics-for-acute-upper-respiratory-tract-infections-in-primary-care
#5
REVIEW
Jack W O'Sullivan, Robert T Harvey, Paul P Glasziou, Amanda McCullough
BACKGROUND: Acute upper respiratory tract infections (URTIs) are frequently managed in primary care settings. Although many are viral, and there is an increasing problem with antibiotic resistance, antibiotics continue to be prescribed for URTIs. Written patient information may be a simple way to reduce antibiotic use for acute URTIs. OBJECTIVES: To assess if written information for patients (or parents of child patients) reduces the use of antibiotics for acute URTIs in primary care...
November 25, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27884215/public-perception-of-emergency-medical-services-in-the-united-states
#6
Remle P Crowe, Roger Levine, Severo Rodriguez, Ashley D Larrimore, Ronald G Pirrallo
OBJECTIVE: The objective of this study was to assess the public's experience, expectations, and perceptions related to Emergency Medical Services (EMS). METHODS: A population-based telephone interview of adults in the United States was conducted. The survey instrument consisted of 112 items. Demographic variables including age, race, political beliefs, and household income were collected. Data collection was performed by trained interviewers from Kent State University's (Kent, Ohio USA)Social Research Laboratory...
November 25, 2016: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/27884153/performance-evaluation-of-the-touchscreen-based-muse%C3%A2-auto-cd4-cd4-single-platform-system-for-cd4-t-cell-numeration-in-absolute-number-and-in-percentage-using-blood-samples-from-children-and-adult-patients-living-in-the-central-african-republic
#7
Christian Diamant Mossoro-Kpinde, André Kouabosso, Ralph-Sydney Mboumba Bouassa, Jean De Dieu Longo, Edouard Kokanzo, Rosine Féissona, Gérard Grésenguet, Laurent Bélec
BACKGROUND: The new microcapillary and fluorescence-based EC IVD-qualified Muse™ Auto CD4/CD4% single-platform assay (EMD Millipore Corporation, Merck Life Sciences, KGaA, Darmstadt, Germany) for CD4 T cell numeration in absolute number and in percentage was evaluated using Central African patients' samples compared against the reference EC IVD-qualified BD FACSCount (Becton-Dickinson, USA) flow cytometer. METHODS: EDTA-blood samples from 124 adults, 10 adolescents, 13 children and 3 infants were tested in parallel at 2 reference laboratories in Bangui...
November 25, 2016: Journal of Translational Medicine
https://www.readbyqxmd.com/read/27882827/creating-a-framework-for-data-sharing-in-cochlear-implant-research
#8
Erin C Schafer, Jedidiah J Grisel, Andrew de Jong, Kimberly Ravelo, Anne Lam, Meredith Burke, Terry Griffin, Margaret Winter, Debra Schrader
OBJECTIVES: To summarize the development process of a national database that was designed to facilitate communication and collaboration, improve care, and create a framework for aggregate data sharing in cochlear implant (CI) research. METHODS: A group of nationally represented, multidisciplinary CI providers cooperated to define a standard set of data elements to incorporate into a database built by them in association with a group of computer scientists and software designers...
November 24, 2016: Cochlear Implants International
https://www.readbyqxmd.com/read/27879980/theory-based-interventions-for-contraception
#9
REVIEW
Laureen M Lopez, Thomas W Grey, Mario Chen, Elizabeth E Tolley, Laurie L Stockton
BACKGROUND: The explicit use of theory in research helps expand the knowledge base. Theories and models have been used extensively in HIV-prevention research and in interventions for preventing sexually transmitted infections (STIs). The health behavior field uses many theories or models of change. However, many educational interventions addressing contraception have no explicit theoretical base. OBJECTIVES: To review randomized controlled trials (RCTs) that tested a theoretical approach to inform contraceptive choice and encourage or improve contraceptive use...
November 23, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27878408/rheumatologists-perception-of-systemic-lupus-erythematosus-quality-indicators-significant-interest-and-perceived-barriers
#10
Carolyn Casey, Cecilia P Chung, Leslie J Crofford, April Barnado
Differences in quality of care may contribute to health disparities in systemic lupus erythematosus (SLE). Studies show low physician adherence rates to the SLE quality indicators but do not assess physician perception of SLE quality indicators or quality improvement. Using a cross-sectional survey of rheumatologists in the southeastern USA, we assessed the perception and involvement of rheumatologists in quality improvement and the SLE quality indicators. Using electronic mail, an online survey of 32 questions was delivered to 568 rheumatologists...
November 22, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27873121/challenges-to-treatment-of-chronic-pain-and-addiction-during-the-opioid-crisis
#11
REVIEW
Daniel Krashin, Natalia Murinova, Mark Sullivan
Health care in the USA faces a double challenge, the crisis of chronic pain and the crisis of opioid misuse and overdose. Patients have been prescribed opioids at high doses with unclear indications for long periods of time, putting them at high risk for morbidity and mortality. A significant proportion of these patients have comorbid psychiatric or substance use disorders complicating their pain conditions. The challenges to treating these patients adequately are discussed, along with potential solutions to these issues at the level of the individual provider, healthcare systems, and society...
December 2016: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/27872551/evaluation-of-fluoride-levels-in-bottled-water-and-their-contribution-to-health-and-teeth-problems-in-the-united-arab-emirates
#12
Mohamed Yehia Z Abouleish
Fluoride is needed for better health, yet if ingested at higher levels it may lead to health problems. Fluoride can be obtained from different sources, with drinking water being a major contributor. In the United Arab Emirates (UAE), bottled water is the major source for drinking. The aim of this research is to measure fluoride levels in different bottled water brands sold in UAE, to determine whether fluoride contributes to better health or health problems. The results were compared to international and local standards...
October 2016: Saudi Dental Journal
https://www.readbyqxmd.com/read/27867426/fragranced-consumer-products-exposures-and-effects-from-emissions
#13
Anne Steinemann
Fragranced consumer products, such as cleaning supplies, air fresheners, and personal care products, are a primary source of indoor air pollutants and personal exposure. Previous research indicates that fragranced products can trigger adverse health effects, with implications for workplaces and public places. This is the first study to examine the multiple dimensions of exposures related to fragranced products and effects in the US population. The study investigated the prevalence and types of fragranced product exposures, associated health effects, awareness of product emissions, and preferences for fragrance-free policies and environments...
2016: Air Quality, Atmosphere, & Health
https://www.readbyqxmd.com/read/27866945/a-global-call-from-five-countries-to-collaborate-in-antibiotic-stewardship-united-we-succeed-divided-we-might-fail
#14
REVIEW
Debra A Goff, Ravina Kullar, Ellie J C Goldstein, Mark Gilchrist, Dilip Nathwani, Allen C Cheng, Kelly A Cairns, Kevin Escandón-Vargas, Maria Virginia Villegas, Adrian Brink, Dena van den Bergh, Marc Mendelson
In February, 2016, WHO released a report for the development of national action plans to address the threat of antibiotic resistance, the catastrophic consequences of inaction, and the need for antibiotic stewardship. Antibiotic stewardship combined with infection prevention comprises a collaborative, multidisciplinary approach to optimise use of antibiotics. Efforts to mitigate overuse will be unsustainable without learning and coordinating activities globally. In this Personal View, we provide examples of international collaborations to address optimal prescribing, focusing on five countries that have developed different approaches to antibiotic stewardship-the USA, South Africa, Colombia, Australia, and the UK...
November 17, 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27865413/evaluation-of-chlorhexidine-hydrochloride-treatment-on-endometrial-health-of-normal-mares
#15
Natalie S Fraser, Aime K Johnson, Robyn R Wilborn, Ghislaine A Dujovne, Leland Nuehring
Chlorhexidine gluconate solution is a potent antimicrobial and therefore could be used effectively for treatment of endometritis, but historically this substance has been implicated as irritating to mucous membranes, including the endometrium of the mare. The use of chlorhexidine hydrochloride suspension (Nolvasan Suspension, Zoetis, Florham Park, NJ, USA) was evaluated in the uterus of normal mares to determine if adverse effects on endometrial health were noted. Twelve healthy, adult light breed mares were included in this study...
January 15, 2017: Theriogenology
https://www.readbyqxmd.com/read/27857997/a-critical-examination-of-the-use-of-trained-health-coaches-to-decrease-the-metabolic-syndrome-for-participants-of-a-community-based-diabetes-prevention-and-management-program
#16
Brandon Lucke-Wold, Samantha Shawley, John Spencer Ingels, Jonathan Stewart, Ranjita Misra
The epidemic of obesity and diabetes in the United States poses major challenge to the prevention and management of chronic diseases. Furthermore, when this is viewed in other components of the metabolic syndrome (i.e., the burden of high cholesterol and hypertension), the prevalence of the metabolic syndrome continues to rise in the USA continued challenge is how to deal with this epidemic from a medical and public health standpoint. Community Based Participatory Research (CBPR) is a unique approach and offers a novel perspective for answering this challenge...
2016: Journal of Healthcare Communications
https://www.readbyqxmd.com/read/27846824/group-based-prenatal-care-in-a-low-and-high-risk-population-in-the-netherlands-a-study-protocol-for-a-stepped-wedge-cluster-randomized-controlled-trial
#17
Birgit S van Zwicht, Matty R Crone, Jan M M van Lith, Marlies E B Rijnders
BACKGROUND: CenteringPregnancy (CP) is a multifaceted group based care-model integrated in routine prenatal care, combining health assessment, education, and support. CP has shown some positive results on perinatal outcomes. However, the effects are less obvious when limited to the results of randomized controlled trials: as there are few trials and there is a variation in reported outcomes. Furthermore, former research was mostly conducted in the United States of America and in specific (often high risk) populations...
November 15, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27845487/health-data-entanglement-and-artificial-intelligence-based-analysis-a-brand-new-methodology-to-improve-the-effectiveness-of-healthcare-services
#18
A Capone, A Cicchetti, F S Mennini, A Marcellusi, G Baio, G Favato
Healthcare expenses will be the most relevant policy issue for most governments in the EU and in the USA. This expenditure can be associated with two major key categories: demographic and economic drivers. Factors driving healthcare expenditure were rarely recognised, measured and comprehended. An improvement of health data generation and analysis is mandatory, and in order to tackle healthcare spending growth, it may be useful to design and implement an effective, advanced system to generate and analyse these data...
September 2016: La Clinica Terapeutica
https://www.readbyqxmd.com/read/27845027/clinical-effectiveness-and-cost-effectiveness-of-use-of-therapeutic-monitoring-of-tumour-necrosis-factor-alpha-tnf-%C3%AE-inhibitors-lisa-tracker%C3%A2-enzyme-linked-immunosorbent-assay-elisa-kits-tnf-%C3%AE-blocker-elisa-kits-and-promonitor%C3%A2-elisa-kits-versus-standard-care
#19
Karoline Freeman, Martin Connock, Peter Auguste, Sian Taylor-Phillips, Hema Mistry, Deepson Shyangdan, Rachel Court, Ramesh Arasaradnam, Paul Sutcliffe, Aileen Clarke
BACKGROUND AND OBJECTIVES: Systematic reviews and economic modelling of clinical effectiveness and cost-effectiveness of therapeutic monitoring of tumour necrosis factor alpha (TNF-α) inhibitors [using LISA-TRACKER(®) enzyme-linked immunosorbent assay (ELISA) kits (Theradiag, Marne La Vallee, France, or Alpha Laboratories, Heriot, UK), TNF-α-Blocker ELISA kits (Immundiagnostik AG, Bensheim, Germany) and Promonitor(®) ELISA kits (Proteomika, Progenika Biopharma, Bizkaia, Spain)] versus standard care for Crohn's disease (CD)...
November 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27837454/diabetes-and-hypertension-in-marshallese-adults-results-from-faith-based-health-screenings
#20
Pearl Anna McElfish, Brett Rowland, Christopher R Long, Jonell Hudson, Michelle Piel, Bill Buron, Sheldon Riklon, Williamina Ioanna Bing, T Scott Warmack
BACKGROUND: The Pacific Islander population in the USA is growing rapidly. However, research on Pacific Islanders in the USA is limited, or sometimes misleading due to aggregation with Asian Americans. This project seeks to add to the dearth of health literature by conducting a health assessment of Marshallese in northwest Arkansas. METHODS: Using a community-based participatory research approach, nine health screening events were conducted at local Marshallese churches...
November 11, 2016: Journal of Racial and Ethnic Health Disparities
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