West

This article examines the rare phenomenon of mainstream Euroscepticism that has characterised the British Conservative Party and asks whether a similar pattern has appeared elsewhere in the EU. The study traces the long-term evolution of salience and positions on the EU issue in the manifestos of a heterogenous set of centre-right parties, paying particular attention to whether Brexit or successive EU crises have had some noticeable effect. The thesis of Tory exceptionalism is largely supported by the findings - no other mainstream conservative party in the EU has talked more, and more negatively, about the EU over a long time period...

Public opinion scholarship suggests that Europeans broadly interpret Brexit as a cautionary fable rather than an encouraging blueprint to follow. Yet, Brexit singularly demonstrates the possibility of European disintegration, and is but one of multiple recent crises that have brought the potential for member state departures into focus. Drawing on new survey data from 16 countries and using logistic regressions, this article charts Europeans' perceptions of the likelihood future EU exits over the next decade...

This introduction to the special issue recalls the alarm raised in EU capitals and Brussels after the UK's in-out referendum delivered a Leave vote in June 2016. The fear was of a domino effect and the further fragmentation of an already divided EU. Seven years later, it is clear that there was rapid attrition of Eurosceptic triumphalism, and the EU-27 showed remarkable unity. This required a sustained collective effort to contain a membership crisis and maintain the EU polity. Yet, the issue contributors challenge the notion that the alarm was unfounded and explain why this counter-factual did not materialise, even though potential for future membership crises of different sorts was revealed...

Brexit constitutes a puzzle for integration theory. Functionalist analyses have not only failed to predict the UK's exit but have also underestimated the disintegrative dynamics of the withdrawal negotiations. By contrast, postfunctionalism accounts for the disintegrative Brexit process but struggles to explain the unity and defence of supranational integration among the EU-27. This article tries to make sense of the Brexit puzzle. First, it argues that Brexit constitutes an attack on the EU polity rather than a policy failure - the type of crisis that functionalist theories explain best...

The use of toilet facilities is a major sanitation intervention, as it reduces the spread of diarrheal diseases. In areas where toilets are misused, human excreta may be disposed of in open fields, bushes, and other open places. However, information about the level of utilization of toilet facilities in developing regions of Ethiopia is limited. Therefore, this study aimed to identify open defecation (OD) levels and determinants of OD among household-owned toilets in Gambella town, Ethiopia. A cross-sectional survey was conducted among 561 households in Gambela Town, using systematic random sampling and questionnaires...

One reason people are motivated to hold right-wing authoritarian beliefs is the need to manage uncertainty. Right-wing authoritarianism provides a stable source of black-and-white 'answers' about the social world - obey established authorities and norms and show hostility to deviants. Right-wing authoritarianism, in turn, is positively associated with more punitive attitudes and judgements. The purpose of this study was to examine the relationship between mock capital jurors' need for cognitive closure and sentencing decisions through right-wing authoritarianism...

Okra ( Abelmoschus esculentus (L.) Moecnh) is a versatile crop that is widely grown in western Ethiopia, despite that it is less researched. This study, therefore, investigates the traditional knowledge, nutritional, and morphological characteristics of two commonly grown okra varieties (Kenketse and Sharma) in west Ethiopia. A semi-structured questionnaire, checklist, and observations were used to collect primary data from households, key informants, and farms. In addition, proximate composition parameters like moisture content, total ash, crude fat, crude protein, crude fiber, utilizable carbohydrates, and gross energy fruits were measured through laboratory analysis...

[This corrects the article DOI: 10.1002/fsn3.3512.].

PURPOSE: The purpose of this study was to compare the preoperative anxiety, aqueous humor monocyte chemoattractant protein-1 (MCP-1) concentration, intraoperative pain, and degree of cooperation of the first eye implantable collamer lens (ICL) surgery with the second eye surgery, of the 1-day interval group with the 1-week interval group, and to investigate the possible causes of these differences, as well as to determine the appropriate interval between bilateral eye ICL surgeries. METHOD: The study was a prospective observational study...

BACKGROUND: Globally, prematurity is the primary factor behind the mortality of children under the age of 5 years, resulting in approximately 1 million children dying annually. The World Health Organization (WHO) recommends Skin-to-Skin Contact (SSC) as part of routine care for preterm infants. Evidence shows that SSC reduces mortality, possibly by improving thermoregulation, facilitating the earlier initiation of breastfeeding and reducing the risk of nosocomial infection. An educational program for implementing SSC has been demonstrated to enhance the knowledge and practice of parents and nurses in intensive care units...

Multidimensional health function impairments are common in older patients with chronic kidney disease (CKD). The purpose of this study was to explore whether the risk or severity of geriatric syndrome increased with a decline in renal function. This survey was conducted for CKD patients aged  ≥ 60 years and hospitalized at West China Hospital of Sichuan University (Center of Gerontology and Geriatrics, Nephrology, and Endocrinology) and Chengdu Kangfu Kidney Disease Hospital from September 01, 2013 to June 30, 2014...

To minimize condylar positional and morphological changes after mandibular advancement through bilateral sagittal split ramus osteotomy (BSSRO), surgeons add either a bicortical screw or a two-hole plate distal to the conventional single miniplate. Since there have been no previous studies investigating the effect of this combination, our study aimed to evaluate the short- and long-term effects of these adjunctive fixation methods (AFM) on condylar positional and morphological changes after mandibular advancement through BSSRO...

BACKGROUND: In metastatic urethral cancer, temporal trends, and patterns of inpatient palliative care (IPC) use are unknown. METHODS: Relying on the National Inpatient Sample (2006-2019), metastatic urethral cancer patients were stratified according to IPC use. Estimated annual percentage changes (EAPC) analyses and multivariable logistic regression models (LRM) for the prediction of IPC use were fitted. RESULTS: Of 1,106 metastatic urethral cancer patients, 199 (18%) received IPC...

INTRODUCTION: An important obstacle in the fight against diabetic retinopathy (DR) is the use of a classification system based on old imaging techniques and insufficient data to accurately predict its evolution. New imaging techniques generate new valuable data, but we lack an adapted classification based on these data. The main objective of the Evaluation Intelligente de la Rétinopathie Diabétique, Intelligent evaluation of DR (EviRed) project is to develop and validate a system assisting the ophthalmologist in decision-making during DR follow-up by improving the prediction of its evolution...

OBJECTIVES: To determine General Practice (GP) recording of carer status and the number of patients self-identifying as carers, while self-completing an automated check-in screen prior to a GP consultation. DESIGN: A descriptive cross-sectional study. SETTING: 11 GPs in the West Midlands, England. Recruitment commenced in September 2019 and concluded in January 2020. PARTICIPANTS: All patients aged 10 years and over, self-completing an automated check-in screen, were invited to participate during a 3-week recruitment period...

INTRODUCTION: Despite recent efforts to increase the participation of women in orthopaedic surgery, there remains a gender gap, particularly when compared with other medical specialties. Acting as a principal investigator (PI) in a clinical trial can give physicians notable exposure and national recognition, which can improve their chances of promotion and tenure. This study aims to assess the proportion of women serving as PIs in pediatric orthopaedic clinical trials, examine associated trial characteristics, and explore geographic distribution...

AIMS: Potential loss-of-function variants of ATP13A3, the gene encoding a P5B-type transport ATPase of undefined function, were recently identified in pulmonary arterial hypertension (PAH) patients. ATP13A3 is implicated in polyamine transport but its function has not been fully elucidated. Here, we sought to determine the biological function of ATP13A3 in vascular endothelial cells and how PAH-associated variants may contribute to disease pathogenesis. METHODS AND RESULTS: We studied the impact of ATP13A3 deficiency and overexpression in endothelial cell (EC) models (human pulmonary ECs, blood outgrowth ECs (BOECs) and HMEC-1 cells), including a PAH patient-derived BOEC line harbouring an ATP13A3 variant (LK726X)...

Monitoring of spatio-temporal changes in crop phenology is an important part of the remote sensing of agricultural ecosystems. In this study, the segment turning point method was utilised to determine several phenological dates of winter wheat in northern Henan from 2003 to 2018. The spatio-temporal variation characteristics of these main phenological dates were analyzed, and the effects of temperature and precipitation on phenological changes were investigated. The results showed that: (1) The segment turning point method had strong space-time adaptability, and the RMSE of extracted phenoloical dates of multi-stations in a single year or single station in multi-years was less than 10d...

Phakopsora nishidana has recently been reported as the causal organism of rust on edible fig, Ficus carica in South Africa (SA) (Boshoff et al. 2022). This contradicted reports by Doidge (1927, 1950) and Verwoerd (1929) who listed Cerotelium fici as the causal organism of the disease in SA. Similarities in urediniospore morphology and differing taxonomic interpretations most likely contributed to the use of both pathogen names as the causal agents for fig rust (Boshoff et al. 2022; Padamsee and McKenzie 2024)...

Breast cancer chemotherapy/immunotherapy can be associated with treatment-limiting cardiotoxicity. Radiomics techniques applied to ultrasound, known as ultrasomics, can be used in cardio-oncology to leverage echocardiography for added prognostic value. To utilize ultrasomics features collected prior to antineoplastic therapy to enhance prediction of mortality and heart failure (HF) in patients with breast cancer. Patients were retrospectively recruited in a study at the West Virginia University Cancer Institute...