Read by QxMD icon Read


Vikram Sood, Osman Alam, Vakhtang Tchantchaleishvili, Francis D Pagani, Keith D Aaronson, Jonathan Haft, David L Joyce, Lyle D Joyce, Richard C Daly, Simon Maltais, John M Stulak
BACKGROUND: Analyses of the HeartMate II left ventricular assist device are routinely performed after explant if returned to the manufacturer. Findings from manufacturer-reported pump analyses have not been correlated with pre-explant serum lactate dehydrogenase (LDH) values. METHODS: Between May 2004 and December 2014, 502 patients underwent primary HeartMate II implantation. Seventy pumps were explanted in 58 patients and returned to the manufacturer for pump analysis: 51 (73%) for suspected pump thrombosis, 12 (17%) for device-related infection, and 7 (13%) for percutaneous lead fracture...
October 12, 2016: Annals of Thoracic Surgery
Désirée Maltais, Ketsia Proulx, Annette Majnemer, Noémi Dahan-Oliel, Barbara Mazer, Line Nadeau
OBJECTIVE: This study aimed to describe relationships between the time adolescents born extremely prematurely spend in moderate-to-vigorous physical activity (MVPA) and selected sociodemographic, prematurity and co-morbidity factors. MATERIAL/PATIENTS AND METHODS: Participants were 64 adolescents, 16.1±2.5years old (57.8% girls), who were born<30weeks gestation. They each wore an accelerometer over the right hip for up to seven days in order to establish their time spent in MVPA...
September 2016: Annals of Physical and Rehabilitation Medicine
Sean Loughlin, Danilo Concepcion, Gema Gonzalez, Jo-Ann Maltais, Carolyn Neuland, Joseph Pulliam, Denny Treu, Richard J Williams
No abstract text is available yet for this article.
September 2016: Biomedical Instrumentation & Technology
Matthew J Leineweber, Dominik Wyss, Sophie-Krystale Dufour, Claire Gane, Karl Zabjek, Laurent J Bouyer, Désirée B Maltais, Julien I Voisin, Jan Andrysek
This study evaluated the effects of intense physical exercise on postural stability of children with cerebral palsy (CP). Center of pressure (CoP) was measured in 9 typically developing (TD) children and 8 with CP before and after a maximal aerobic shuttle-run test (SRT) using a single force plate. Anteroposterior and mediolateral sway velocities, sway area, and sway regularity were calculated from the CoP data and compared between pre- and postexercise levels and between groups. Children with CP demonstrated significantly higher pre-SRT CoP velocities than TD children in the sagittal (18...
July 2016: Adapted Physical Activity Quarterly: APAQ
François Lellouche, Pierre-Alexandre Bouchard, Maude Roberge, Serge Simard, Erwan L'Her, François Maltais, Yves Lacasse
INTRODUCTION: We developed a device (FreeO2) that automatically adjusts the oxygen flow rates based on patients' needs, in order to limit hyperoxia and hypoxemia and to automatically wean them from oxygen. OBJECTIVE: The aim of this study was to evaluate the feasibility of using FreeO2 in patients hospitalized in the respiratory ward for an acute exacerbation of COPD. METHODS: We conducted a randomized controlled trial comparing FreeO2 vs manual oxygen titration in the respiratory ward of a university hospital...
2016: International Journal of Chronic Obstructive Pulmonary Disease
Jo-Ann B Maltais, Klemens B Meyer, Meredith C Foster
Introduction Microbiological culture of dialysis water and fluid is a routine safety measure. In the United States (U.S.), laboratories perform these cultures on trypticase soy agar at 35-37°C for 48 h (TSA-48h), not on the tryptone glucose extract agar or Reasoner's 2A agar at 17-23°C for 7 days (TGEA-7d and R2A-7d, respectively) recommended by international standards. We compared culture methods to identify samples exceeding the accepted action level of 50 CFU/mL. Methods Dialysis water and fluid samples collected from 41 U...
September 5, 2016: Hemodialysis International
Palak Shah, Francis D Pagani, Shashank S Desai, Anthony J Rongione, Simon Maltais, Nicholas A Haglund, Shannon M Dunlay, Keith D Aaronson, John M Stulak, Mary Beth Davis, Christopher T Salerno, Jennifer A Cowger
BACKGROUND: Temporary circulatory support (TCS) is used to stabilize patients in critical cardiogenic shock and bridge patients to a durable ventricular assist device (VAD). Whether TCS confers increased risk at the time of VAD implant is unknown. METHODS: Prospectively collected data from five institutions was retrospectively reviewed. All profile 1 through profile 3 patients implanted with a continuous-flow VAD (n = 804) were categorized into three groups: TCS (n = 68); non-TCS profile 1 (n = 70); and non-TCS profile 2-3 (n = 666)...
August 28, 2016: Annals of Thoracic Surgery
G A Handrigan, N Maltais, M Gagné, P Lamontagne, D Hamel, N Teasdale, O Hue, P Corbeil, J P Brown, S Jean
: This study investigated the relationship between body mass index (BMI) and falls among community-dwelling elderly. Results indicate that obesity is associated with increased falls and there appears to be a sex-specific difference with obese men at higher risk of falling. Obesity is identified as a risk factor for falls in men. INTRODUCTION: The prevalence of falls, fall-related injuries, and obesity has increased over the last decade. The objectives of this study were to investigate sex-specific association and dose-response relationship between BMI and falls (and related injuries) among community-dwelling elderly...
August 25, 2016: Osteoporosis International
Simon Maltais, Mary E Davis, Nicholas A Haglund, Louis Perrault, Sudhir S Kushwaha, John M Stulak, Edward M Boyle
Chest tubes are utilized to evacuate shed blood after left ventricular assist device (LVAD) implantation, however, they can become clogged, leading to retained blood. We implemented a protocol for active tube clearance (ATC) of chest tubes to determine if this might reduce interventions for retained blood. 252 patients underwent LVAD implantation. 77 had conventional chest tube drainage (Group 1), whereas 175 patients had ATC (Group 2). A univariate and multivariate analysis adjusting for the use of conventional sternotomy (CS) and minimally invasive left thoracotomy (MILT) was performed...
August 22, 2016: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Martin Perreault, René Maltais, Raphaël Dutour, Donald Poirier
RM-133 is a key representative of a new family of aminosteroids reported as potent anticancer agents. Although RM-133 produced interesting results in 4 mouse xenograft cancer models when injected subcutaneously, it needs to be improved to increase its in vivo potency. Thus, to obtain an analog of RM-133 with a better drug potential, a structure-activity relationship study was conducted by synthesizing eleven RM-133-related compounds and addressing their antiproliferative activity on 3 human cancer cells (HL-60, OVCAR-3 and PANC-1) and 3 human normal cell lines (primary ovary, pancreas and renal proximal tubule) as well as their metabolic stability in human liver microsomes...
November 2016: Steroids
André Nyberg, João Carvalho, Kim-Ly Bui, Didier Saey, François Maltais
Even though chronic obstructive pulmonary disease (COPD) is primarily a disease of the respiratory system, limb muscle dysfunction characterized by muscle weakness, reduced muscle endurance and higher muscle fatigability, is a common secondary consequence and a major systemic manifestation of the disease. Muscle dysfunction is especially relevant in COPD because it is related to important clinical outcomes such as mortality, quality of life and exercise intolerance, independently of lung function impairment...
August 10, 2016: Revista Portuguesa de Pneumologia
François Maltais, Anne-Marie Kirsten, Alan Hamilton, Dorothy De Sousa, Florian Voß, Marc Decramer
BACKGROUND: Two replicate, double-blind, placebo-controlled, 6-week crossover studies assessed the effect of the once-daily long-acting β2-agonist olodaterol 5 μg and 10 μg on constant work-rate cycle endurance in patients with moderate to very severe chronic obstructive pulmonary disease. METHODS: Patients received placebo, olodaterol 5 μg once daily (QD) and olodaterol 10 μg QD in a randomised order for 6 weeks each, with a 2-week washout period in between...
2016: Respiratory Research
N Gupta, L Pinto, A Benedetti, P Z Li, W Tan, S Aaron, K R Chapman, J M FitzGerald, P Hernandez, D Marciniuk, F Maltais, D O'Donnell, D Sin, B Walker, J Bourbeau
BACKGROUND: The COPD Assessment Test (CAT) is a valid disease specific questionnaire measuring health status. However, knowledge concerning its use regarding patient and disease characteristics remains limited. Our main objective was to assess the degree to which the CAT score varies and can discriminate between specific patient population groups. METHODS: The Canadian Cohort Obstructive Lung Disease (CanCOLD) is a random-sampled population-based, multicenter prospective cohort that includes subjects with COPD: GOLD 1 to 3...
June 27, 2016: Chest
Isabelle Demers, Hélène Moffet, Luc J Hébert, Désirée B Maltais
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Christopher J Ryerson, Pat G Camp, Neil D Eves, Michele Schaeffer, Nafeez Syed, Satvir Dhillon, Dennis Jensen, Francois Maltais, Denis E O'Donnell, Natya Raghavan, Michael Roman, Michael K Stickland, Deborah Assayag, Jean Bourbeau, Genevieve Dion, Charlene D Fell, Nathan Hambly, Kerri A Johannson, Meena Kalluri, Nasreen Khalil, Martin Kolb, Helene Manganas, Onofre Morán-Mendoza, Steve Provencher, Warren Ramesh, J Douglass Rolf, Pearce G Wilcox, Jordan A Guenette
RATIONALE: Pulmonary rehabilitation improves dyspnea and exercise capacity in idiopathic pulmonary fibrosis (IPF); however, it is unknown whether breathing high amounts of oxygen during exercise training leads to further benefits. OBJECTIVES: Herein, we describe the design of the High Oxygen Delivery to Preserve Exercise Capacity in IPF Patients Treated with Nintedanib study (the HOPE-IPF study). The primary objective of this study is to determine the physiological and perceptual impact of breathing high levels of oxygen during exercise training in patients with IPF who are receiving antifibrotic therapy...
September 2016: Annals of the American Thoracic Society
Bantayehu Sileshi, Brian K O'Hara, Mary E Davis, Nicholas A Haglund, Xu Meng, Robert Deegan, John M Stulak, Sudhir S Kushwaha, Andrew Shaw, Simon Maltais
As ventricular-assist devices (VADs) are increasingly employed in heart failure management, a leading cause of mortality, new literature is consistently published on less-invasive implantation techniques. Although early perioperative outcomes have been shown to be favorable with minimally invasive left thoracotomy (LT) approaches compared with conventional sternotomy (CS), studies comparing long-term outcomes are lacking. We set out to evaluate long-term follow up between LT and CS approach. In a single center, retrospective review, data on patients with similar demographic profiles were collected...
September 2016: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Luc J Hébert, Désirée Maltais
No abstract text is available yet for this article.
2016: Pediatric Physical Therapy
Thora R Maltais, Avijit K Adak, Waleed Younis, Mohamed N Seleem, Alexander Wei
Hemin linked to hexa(ethylene glycol)bishydrazide was patterned by inkjet printing into periodic microarrays, and evaluated for their ability to capture bacterial pathogens expressing various hemin receptors. Bacterial adhesion was imaged under darkfield conditions with Fourier analysis, supporting a label-free method of pathogen detection. Hemin microarrays were screened against a panel of 16 bacteria and found capable of capturing multiple species, some with limits of detection as low as 10(3) cfu/mL. Several Gram-positive strains including Staphylococcus aureus and Bacillus anthracis also exhibited rapid adhesion, enabling pattern recognition within minutes of exposure...
July 20, 2016: Bioconjugate Chemistry
André Nyberg, Didier Saey, Mickaël Martin, François Maltais
: Exercising small muscle groups at a time allows higher muscle specific workloads compared to whole body aerobic exercises in people with chronic obstructive pulmonary disease (COPD). Whether similar effects also occur with partitioning exercise during low load/high-repetition resistance exercises is uncertain. PURPOSE: To investigate the acute effects of partitioning exercise on exercise workload, exertional symptoms and quadriceps muscle fatigue during low load/high-repetition resistance exercises in people with COPD and healthy controls...
June 23, 2016: Medicine and Science in Sports and Exercise
Isabelle Vivodtzev, Monique Mendelson, Marilie Croteau, Sandy Gorain, Bernard Wuyam, Renaud Tamisier, Patrick Lévy, François Maltais, Jean-Louis Pépin
BACKGROUND/OBJECTIVES: Physical activity is promoted in patients with sleep disorders and obesity. The aim of the present study was to assess physiological factors influencing objectively measured spontaneous physical activity in already treated patients for obstructive sleep apnea (OSA) by nocturnal continuous positive airway pressure (CPAP). SUBJECTS/METHODS: Fifty-five patients (age = 53 ± 3 years; body mass index (BMI) = 38 ± 3 kg/m(2); compliance with CPAP >4 h/night) were prospectively included...
June 18, 2016: Sleep & Breathing, Schlaf & Atmung
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"