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https://www.readbyqxmd.com/read/28093920/inspiratory-muscle-training-is-effective-to-reduce-postoperative-pulmonary-complications-and-length-of-hospital-stay-a-systematic-review-and-meta-analysis
#1
Filipa Kendall, José Oliveira, Bárbara Peleteiro, Paulo Pinho, Pedro Teixeira Bastos
PURPOSE: This study systematically review and meta-analyse the effectiveness of inspiratory muscle training (IMT) to reduce postoperative pulmonary complications (PPC) and length of hospital stay (LOS), both in the preoperative and/or postoperative periods of cardiac, pulmonary, and abdominal surgical patients. Sensitive analysis was performed to examine which patients benefit more from IMT according to methodological features (quality of studies and sample size), patient's characteristics (pulmonary risk stratification, age, and body mass index), type of surgery, period of training, and training protocols (training doses and level of supervision)...
January 17, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28093429/paediatric-ed-bipap-continuous-quality-improvement-programme-with-patient-analysis-2005-2013
#2
Thomas Abramo, Abby Williams, Samaiya Mushtaq, Mark Meredith, Rawle Sepaule, Kristen Crossman, Cheryl Burney Jones, Suzanne Godbold, Zhuopei Hu, Todd Nick
OBJECTIVE: In paediatric moderate-to-severe asthmatics, there is significant bronchospasm, airway obstruction, air trapping causing severe hyperinflation with more positive intraplural pressure preventing passive air movement. These effects cause an increased respiratory rate (RR), less airflow and shortened inspiratory breath time. In certain asthmatics, aerosols are ineffective due to their inadequate ventilation. Bilevel positive airway pressure (BiPAP) in acute paediatric asthmatics can be an effective treatment...
January 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/28087053/six-minute-walk-test-results-predict-risk-of-hospitalization-for-youths-with-cystic-fibrosis-a-5-year-follow-up-study
#3
Márcio V F Donadio, João P Heinzmann-Filho, Fernanda M Vendrusculo, Patrícia X H Frasson, Paulo J C Marostica
OBJECTIVE: To evaluate the association of 6-minute walk test (6MWT) and other variables (anthropometry, chronic Pseudomonas aeroginosa colonization, pulmonary function, and respiratory muscle strength) with the risk of hospitalization for pulmonary exacerbation in children and adolescents with cystic fibrosis (CF). STUDY DESIGN: Cohort study that included patients with CF aged 6-18 years. All participants underwent spirometry, manovacuometry, and 6MWT during the 5-year follow-up...
January 10, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28076295/convolutive-blind-source-separation-of-surface-emg-measurements-of-the-respiratory-muscles
#4
Eike Petersen, Herbert Buchner, Marcus Eger, Philipp Rostalski
Electromyography (EMG) has long been used for the assessment of muscle function and activity and has recently been applied to the control of medical ventilation. For this application, the EMG signal is usually recorded invasively by means of electrodes on a nasogastric tube which is placed inside the esophagus in order to minimize noise and crosstalk from other muscles. Replacing these invasive measurements with an EMG signal obtained non-invasively on the body surface is difficult and requires techniques for signal separation in order to reconstruct the contributions of the individual respiratory muscles...
January 11, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28063860/could-objective-tests-be-used-to-measure-fatigue-in-patients-with-advanced-cancer
#5
Gustavo Schvartsman, Minjeong Park, Diane D Liu, Sriram Yennu, Eduardo Bruera, David Hui
CONTEXT: Assessment of cancer-related fatigue is currently based on patient-reported outcomes. We asked whether objective assessments such as muscle strength and nutritional markers can be used as surrogate measures of cancer-related fatigue. OBJECTIVE: We examined the association among three fatigue scales, muscle strength, and nutritional markers in patients with advanced cancer. METHODS: In this prospective study, we enrolled hospitalized cancer patients who had been seen in palliative care consultation at MD Anderson Cancer Center...
January 4, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28063152/dysfunction-of-central-control-of-breathing-in-amyotrophic-lateral-sclerosis
#6
Bradley N Howell, Daniel S Newman
Dysfunction in central control of breathing in some amyotrophic lateral sclerosis (ALS) patients is not adequately detected with standard evaluation for respiratory dysfunction. Nocturnal oximetry reveals periodic desaturations despite normal respiratory muscle movements. Continuous diaphragmatic electromyography has provided in vivo data consistent with impaired central control of diaphragm motor units. Current understanding of central control of breathing identifies the pre-Botzinger complex as the inspiratory rhythm generator...
January 7, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28057838/temporal-evolution-of-thoracocentesis-induced-changes-in-spirometry-and-respiratory-muscle-pressures
#7
Stylianos A Michaelides, George D Bablekos, Antonis Analitis, George Ionas, Petros Bakakos, Konstantinos A Charalabopoulos
BACKGROUND: Several studies investigated the effects of thoracocentesis on aspects of respiratory function without generally ensuring absence of coexistent lung pathology or homogeneity in initial size of the effusion. METHODS: We studied 90 patients aged 61.6±15.9 years (mean±SD) separated into a group A with small-sized or medium-sized effusion (A=56 patients) and a group B with large and massive one (B=34 patients). There was no significant lung lesion or cardiovascular pathology...
January 5, 2017: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/28032568/seven-day-intensive-preoperative-rehabilitation-for-elderly-patients-with-lung-cancer-a-randomized-controlled-trial
#8
Yutian Lai, Jian Huang, Mei Yang, Jianhua Su, Jing Liu, Guowei Che
BACKGROUND: As a newly developed treatment, preoperative pulmonary rehabilitation (PR) has been studied in depth. However, few studies have assessed the relationship between advanced age and a shorter term intensive pattern of preoperative PR in patients with lung cancer (LC) and especially those patients waiting for therapeutic LC surgeries. This study investigated short-term preoperative PR combined with inspiratory muscle training (IMT) and aerobic endurance training in elderly patients scheduled to undergo LC lobectomy...
September 28, 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/28018247/diaphragm-muscle-adaptation-to-sustained-hypoxia-lessons-from-animal-models-with-relevance-to-high-altitude-and-chronic-respiratory-diseases
#9
REVIEW
Philip Lewis, Ken D O'Halloran
The diaphragm is the primary inspiratory pump muscle of breathing. Notwithstanding its critical role in pulmonary ventilation, the diaphragm like other striated muscles is malleable in response to physiological and pathophysiological stressors, with potential implications for the maintenance of respiratory homeostasis. This review considers hypoxic adaptation of the diaphragm muscle, with a focus on functional, structural, and metabolic remodeling relevant to conditions such as high altitude and chronic respiratory disease...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27998434/-effect-of-bcyrn1-on-proliferation-and-migration-of-airway-smooth-muscle-cells-in-rat-model-of-asthma
#10
X Y Zhang, L J Ma, Y L Guo, S Gao, L M Zhao, X S Li, X Y Tang, D J Cheng, L X Zhang, Z C Chen
Objective: To detect the effect of brain cytoplasmic RNA 1 (BCYRN1) on the proliferation and migration of airway smooth muscle cells (ASMCs) in rat model of asthma. Methods: Male SD rats were randomly divided into control group and asthma group (n=10 each). The ovalbumin (OVA) model was constructed in asthma group. Real time-qPCR was performed to detect the level of BCYRN1 in the ASMCs separated from the airway tissue of these rats. Then 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-(2, 4-disulfophenyl)-2H-tetrazolium (WST-1) assay, roche real-time cell analyzer assay and Transwell cell migration assay were performed to detect the viability/proliferation and migration of ASMCs which were transfected with Ad-BCYRN1...
December 13, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27997251/changes-of-respiratory-mechanics-in-copd-patients-from-stable-state-to-acute-exacerbations-with-respiratory-failure
#11
Piero Ceriana, Michele Vitacca, Annalisa Carlucci, Mara Paneroni, Lara Pisani, Stefano Nava
Symptoms, clinical course, functional and biological data during an exacerbation of chronic obstructive pulmonary disease (EXCOPD) have been investigated, but data on physiological changes of respiratory mechanics during a severe exacerbation with respiratory acidosis requiring noninvasive mechanical ventilation (NIMV) are scant. The aim of this study was to evaluate changes of respiratory mechanics in COPD patients comparing data observed during EXCOPD with those observed during stable state in the recovery phase...
December 20, 2016: COPD
https://www.readbyqxmd.com/read/27982348/a-cycle-ergometer-exercise-program-improves-exercise-capacity-and-inspiratory-muscle-function-in-hospitalized-patients-awaiting-heart-transplantation-a-pilot-study
#12
Patrícia Forestieri, Solange Guizilini, Monique Peres, Caroline Bublitz, Douglas W Bolzan, Isadora S Rocco, Vinícius B Santos, Rita Simone L Moreira, João R Breda, Dirceu R de Almeida, Antonio Carlos de C Carvalho, Ross Arena, Walter J Gomes
Objective: The purpose of this study was to evaluate the effect of a cycle ergometer exercise program on exercise capacity and inspiratory muscle function in hospitalized patients with heart failure awaiting heart transplantation with intravenous inotropic support. Methods: Patients awaiting heart transplantation were randomized and allocated prospectively into two groups: 1) Control Group (n=11) - conventional protocol; and 2) Intervention Group (n=7) - stationary cycle ergometer exercise training...
September 2016: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27978772/initiation-of-non-invasive-ventilation-in-amyotrophic-lateral-sclerosis-and-clinical-practice-guidelines-single-centre-retrospective-descriptive-study-in-a-national-reference-centre
#13
Marjolaine Georges, Jean-Louis Golmard, Claudia Llontop, Amr Shoukri, François Salachas, Thomas Similowski, Capucine Morelot-Panzini, Jésus Gonzalez-Bermejo
In amyotrophic lateral sclerosis (ALS), respiratory muscle weakness leads to respiratory failure. Non-invasive ventilation (NIV) maintains adequate ventilation in ALS patients. NIV alleviates symptoms and improves survival. In 2006, French guidelines established criteria for NIV initiation based on limited evidence. Their impact on clinical practice remains unknown. Our objective was to describe NIV initiation practices of the main French ALS tertiary referral centre with respect to guidelines. In this retrospective descriptive study, 624 patients followed in a single national reference centre began NIV between 2005 and 2013...
December 15, 2016: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/27940276/maximal-inspiratory-pressure-does-the-choice-of-reference-values-actually-matter
#14
Antenor Rodrigues, Marianne L Da Silva, Danilo C Berton, Gerson Cipriano, Fabio Pitta, Denis E O'Donnell, J Alberto Neder
BACKGROUND: Single-point measurements of maximal inspiratory pressure (MIP) are frequently used to suggest muscle weakness in clinical practice. Although there is a large variability in "mean" predicted MIP depending on the chosen reference values, it remains unclear whether those discrepancies actually impact on the prevalence of weakness, i.e., MIP below the lower limit of normal. METHODS: 1729 subjects (50.1% males, aged 20 to 94) who underwent MIP measurements in a clinical laboratory comprised the study group...
December 8, 2016: Chest
https://www.readbyqxmd.com/read/27929389/diaphragm-dysfunction-diagnostic-approaches-and-management-strategies
#15
REVIEW
Bruno-Pierre Dubé, Martin Dres
The diaphragm is the main inspiratory muscle, and its dysfunction can lead to significant adverse clinical consequences. The aim of this review is to provide clinicians with an overview of the main causes of uni- and bi-lateral diaphragm dysfunction, explore the clinical and physiological consequences of the disease on lung function, exercise physiology and sleep and review the available diagnostic tools used in the evaluation of diaphragm function. A particular emphasis is placed on the clinical significance of diaphragm weakness in the intensive care unit setting and the use of ultrasound to evaluate diaphragmatic action...
December 5, 2016: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/27923982/effect-of-expiratory-positive-airway-pressure-on-tidal-volume-during-non-invasive-ventilation
#16
W Kinnear, L Watson, P Smith, L Johnson, S Burrows, J Colt, M Sovani, A Khanna
During non-invasive ventilation (NIV), tidal volume (V t) will depend upon the difference between inspiratory and expiratory positive airway pressure (IPAP and EPAP, respectively), provided the respiratory muscles are relaxed and the lungs and chest wall therefore move along their passive pressure-volume curves. To test this hypothesis, we studied the effect of increasing EPAP during pressure-controlled modes of NIV in 30 long-term ventilator users (10 each with scoliosis, obesity hypoventilation or neuromuscular disorders)...
December 6, 2016: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/27923938/computerized-respiratory-sounds-novel-outcomes-for-pulmonary-rehabilitation-in-copd
#17
Cristina Jácome, Alda Marques
BACKGROUND: Computerized respiratory sounds are a simple and noninvasive measure to assess lung function. Nevertheless, their potential to detect changes after pulmonary rehabilitation (PR) is unknown and needs clarification if respiratory acoustics are to be used in clinical practice. Thus, this study investigated the short- and mid-term effects of PR on computerized respiratory sounds in subjects with COPD. METHODS: Forty-one subjects with COPD completed a 12-week PR program and a 3-month follow-up...
December 6, 2016: Respiratory Care
https://www.readbyqxmd.com/read/27922742/the-diaphragm-acts-as-a-brake-during-expiration-to-prevent-lung-collapse
#18
Mariangela Pellegrini, Göran Hedenstierna, Agneta Roneus, Monica Segelsjö, Anders Larsson, Gaetano Perchiazzi
RATIONALE: The diaphragm is the major inspiratory muscle and is assumed to relax during expiration. However, electrical post-inspiratory activity has been observed. Whether or not there is an expiratory diaphragmatic contraction that preserves lung patency has yet to be explored. OBJECTIVE: We hypothesized the occurrence of an expiratory diaphragmatic contraction directed at stabilizing peripheral airways and preventing or reducing cyclic expiratory lung collapse...
December 6, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27912964/a-systematic-review-and-meta-analysis-of-the-herbal-formula-buzhong-yiqi-tang-for-stable-chronic-obstructive-pulmonary-disease
#19
REVIEW
Yuanbin Chen, Johannah Linda Shergis, Lei Wu, Xuhua Yu, Qigang Zeng, Yinji Xu, Xinfeng Guo, Anthony Lin Zhang, Charlie Changli Xue, Lin Lin
OBJECTIVE: To systematically evaluate the efficacy and safety of Buzhong Yiqi Tang (BZYQT) for stable chronic obstructive pulmonary disease (COPD). METHODS: Three electronic English databases (PubMed, EMBASE and CENTRAL) and four Chinese databases (CBM, CNKI, CQVIP and WFMO) were searched from their inceptions until 30th June 2016. Participants were diagnosed with COPD according to the Chinese Medical Association's COPD diagnosis and treatment guidelines or Global Initiative for Chronic Obstructive Lung Disease (GOLD), and were in stable stage...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27908251/effects-of-an-outpatient-service-rehabilitation-programme-in-patients-affected-by-pulmonary-arterial-hypertension-an-observational-study
#20
Maurizio Bussotti, Paola Gremigni, Roberto Fe Pedretti, Patrycja Kransinska, Silvia Di Marco, Paola Corbo, Giovanni Marchese, Paolo Totaro, Marinella Sommaruga
BACKGROUND: Pulmonary arterial hypertension (PAH) is a rare disease characterised by a severe impairment of functional status and quality of life (QoL). Use of rehabilitative programmes may help to improve outcomes. The aim of this pre/post test case series was to evaluate the impact of a training program, including sessions of aerobic and resistance exercise, inspiratory muscle reinforcement, slow breathing, relaxation, and psychological support, on functional outcomes. METHODS: Fifteen patients affected by PAH, in World Health Organization (WHO) Functional Class (FC) II or III and in stable clinical condition, were included in a 4-week cardiorespiratory training programme conducted in outpatient service...
November 30, 2016: Cardiovascular & Hematological Disorders Drug Targets
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