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Inspiratory muscles

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https://www.readbyqxmd.com/read/29342462/reference-values-for-respiratory-muscle-strength-in-children-and-adolescents
#1
Erik Hulzebos, Tim Takken, Elja A Reijneveld, Mark M G Mulder, Bart C Bongers
BACKGROUND: Measurement of respiratory muscle function is important in the diagnosis of respiratory muscle disease, respiratory failure, to assess the impact of chronic diseases, and/or to evaluate respiratory muscle function after treatment. OBJECTIVES: To establish reference values for maximal inspiratory and expiratory pressure, and the tension-time index at rest in healthy children and adolescents aged 8-19 years, as well as to present sex- and age-related reference centiles normalized for demographic and anthropometric determinants...
January 17, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29334157/elevated-sympathetic-vasomotor-outflow-in-response-to-increased-inspiratory-muscle-activity-during-exercise-is-less-in-young-women-compared-with-men
#2
Keisho Katayama, Joshua R Smith, Kanako Goto, Kaori Shimizu, Mitsuru Saito, Koji Ishida, Teruhiko Koike, Satoshi Iwase, Craig A Harms
We compared changes in muscle sympathetic nerve activity (MSNA) and cardiovascular variables during leg cycle exercise with increased inspiratory muscle resistance in men and women. We hypothesized that sympathetic vasomotor outflow during exercise with increased inspiratory resistance would be attenuated in young women compared with age-matched men. Eight women and seven men completed the study. The subjects performed two 10-min exercise bouts at 40% peak oxygen uptake using a cycle ergometer in a semirecumbent position [spontaneous breathing for 5 min and voluntary hyperventilation with or without inspiratory resistive breathing for 5 min (breathing frequency: 50 breaths min-1 with a 50% duty cycle, inspiratory resistance: 30% of maximal inspiratory pressure)]...
January 15, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29329328/early-occurrence-of-inspiratory-muscle-weakness-in-parkinson-s-disease
#3
Guillaume Baille, Thierry Perez, David Devos, Valérie Deken, Luc Defebvre, Caroline Moreau
INTRODUCTION: In Parkinson's disease (PD), respiratory insufficiency (including functional and muscle disorders) can impact dysarthria and swallowing. Most studies of this topic have been performed retrospectively in populations of patients with advanced PD. The objective of the present study was to characterize lung function (under off-drug conditions) in early-stage PD patients at baseline and then again two years later. METHODS: Forty-one early-stage PD patients (mean ± SD age: 61...
2018: PloS One
https://www.readbyqxmd.com/read/29323536/high-positive-end-expiratory-pressure-renders-spontaneous-effort-non-injurious
#4
Caio C A Morais, Yukiko Koyama, Takeshi Yoshida, Glauco M Plens, Susimeire Gomes, Cristhiano L A S Lima, Ozyres P Ramos, Sérgio M Pereira, Naomasa Kawaguchi, Hirofumi Yamamoto, Akinori Uchiyama, João B Borges, Marcos F Vidal Melo, Mauro R Tucci, Marcelo B P Amato, Brian P Kavanagh, Eduardo L V Costa, Yuji Fujino
RATIONALE: In ARDS, atelectatic 'solid-like' lung tissue impairs transmission of negative 'swings' in pleural pressure (Ppl) resulting from diaphragmatic contraction. The localization of more negative Ppl proportionally increases dependent lung stretch by drawing gas either from other lung regions, e.g., non-dependent lung (Pendelluft) or from the ventilator. Lowering of the level of spontaneous effort and/or converting solid-like to fluid-like lung might render spontaneous effort non-injurious...
January 11, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29321341/exercise-tolerance-and-balance-of-inspiratory-to-expiratory-muscle-strength-in-relation-to-breathing-timing-in-patients-with-chronic-obstructive-pulmonary-disease
#5
Keisuke Miki, Kazuyuki Tsujino, Tatsuya Edahiro, Seigo Kitada, Mari Miki, Kenji Yoshimura, Hiroyuki Kagawa, Yohei Oshitani, Yuko Ohara, Yuki Hosono, Hiroyuki Kurebe, Ryoji Maekura
Little is known about the applicability of respiratory muscle training based on exertional pathophysiological conditions in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to investigate the relationship between breathing timing and exertional responses, as well as whether exertional changes in the inspiratory duty cycle (inspiratory time [Ti]/total time [Ttot]) affect pathophysiological conditions, including respiratory muscles. Methods: Forty-five stable COPD patients (mean age: 71...
January 11, 2018: Journal of Breath Research
https://www.readbyqxmd.com/read/29318917/the-effectiveness-of-combining-inspiratory-muscle-training-with-manual-therapy-and-a-therapeutic-exercise-program-on-maximum-inspiratory-pressure-in-adults-with-asthma-a-randomized-clinical-trial
#6
Ibai López-de-Uralde-Villanueva, Pablo Candelas-Fernández, Beatriz de-Diego-Cano, Orcález Mínguez-Calzada, Tamara Del Corral
OBJECTIVE: The objective of this study was to evaluate whether the addition of manual therapy and therapeutic exercise protocol to inspiratory muscle training was more effective in improving maximum inspiratory pressure than inspiratory muscle training in isolation. DESIGN: This is a single-blinded, randomized controlled trial. SUBJECTS: In total, 43 patients with asthma were included in this study. INTERVENTIONS: The patients were allocated into one of the two groups: (1) inspiratory muscle training ( n = 21; 20-minute session) or (2) inspiratory muscle training (20-minute session) combined with a program of manual therapy (15-minute session) and therapeutic exercise (15-minute session; n = 22)...
January 1, 2018: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29315169/health-benefits-of-an-innovative-exercise-program-for-mitochondrial-disorders
#7
Carmen Fiuza-Luces, Jorge Díez-Bermejo, Miguel Fernández-de la Torre, Gabriel Rodríguez-Romo, Paz Sanz-Ayán, Aitor Delmiro, Diego Munguía-Izquierdo, Irene Rodríguez-Gómez, Ignacio Ara, Cristina Domínguez-González, Joaquín Arenas, Miguel A Martín, Alejandro Lucia, María Morán
PURPOSE: We determined the effects of an innovative 8-week exercise intervention (aerobic, resistance and inspiratory muscle training) for patients with mitochondrial disease (MD). METHODS: Several endpoints were assessed in 12 patients (19-59 years, 4 female) at pre-training, post-training and after 4-week detraining: aerobic power, muscle strength/power and maximal inspiratory pressure (main endpoints), ability to perform activities of daily living (ADL), body composition, quality of life and blood myokines (secondary endpoints)...
January 8, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29311394/exercise-capacity-and-respiratory-profile-in-patients-after-orthopedic-liver-transplantation-a-follow-up-study
#8
Clarissa B A Magalhães, José Huygens P Garcia, Cyntia F G Viana, Maria José N Flor, Pedro Felipe C de Bruin, Eanes D B Pereira
INTRODUCTION: We sought to describe: 1) The influence of orthotopic liver transplantation (OLT) on exercise capacity, pulmonary function and respiratory muscle strength after surgery, 2) The relationship between exercise capacity and symptoms of anxiety and depression. MATERIAL AND METHODS: This is a prospective follow up study conducted with patients submitted to OLT. All patients were assessed before and 1 month after surgery through measurements: six minute walk test (6MWT), 6 min step test (6MST) and HADS (Hospital Anxiety and Depression Scale)...
December 27, 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/29305050/intraspinal-microstimulation-for-respiratory-muscle-activation
#9
Michael D Sunshine, Comron N Ganji, Paul J Reier, David D Fuller, Chet T Moritz
A complex propriospinal network is synaptically coupled to phrenic and intercostal motoneurons, and this makes it difficult to predict how gray matter intraspinal microstimulation (ISMS) will recruit respiratory motor units. We therefore mapped the cervical and high thoracic gray matter at locations which ISMS activates diaphragm (DIA) and external intercostal (EIC) motor units. Respiratory muscle electromyography (EMG) was recorded in anesthetized female spinally intact adult rats while a stimulating electrode was advanced ventrally into the spinal cord in 600μm increments...
January 2, 2018: Experimental Neurology
https://www.readbyqxmd.com/read/29303008/behavioural-modes-of-adherence-to-inspiratory-muscle-training-in-people-with-chronic-obstructive-pulmonary-disease-a-grounded-theory-study
#10
Dorthe Sørensen, Marie Ernst Christensen
PURPOSE: Our aim was to develop a theoretical account of the behavioural pattern of adherence to home-based inspiratory muscle training (IMT) in people with chronic obstructive pulmonary disease (COPD), performed as two daily sessions of 30 breaths with mechanical threshold loading. METHODS: This was a qualitative study based on the classic grounded theory method. We conducted interviews with people living with COPD recruited after completion of 6 weeks of outpatient pulmonary rehabilitation program in 2015...
January 5, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29289723/diaphragm-muscle-dysfunction-in-patients-with-heart-failure
#11
Mari Miyagi, Yoshiharu Kinugasa, Takeshi Sota, Kensaku Yamada, Takuya Ishisugi, Masayuki Hirai, Kiyotaka Yanagihara, Nobuhiko Haruki, Koichi Matsubara, Masahiko Kato, Kazuhiro Yamamoto
BACKGROUND: Inspiratory muscle weakness is associated with the development of exercise intolerance in patients with heart failure (HF). Ultrasound assessment of the diaphragm is used to evaluate respiratory muscle function, but its application in patients with HF remains undefined. We examined the relationship of diaphragm function as assessed by ultrasonography with inspiratory muscle strength and exercise tolerance in HF. METHODS AND RESULTS: Seventy-seven patients hospitalized with HF were enrolled...
December 28, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/29289553/advanced-aging-causes-diaphragm-functional-abnormalities-global-proteome-remodeling-and-loss-of-mitochondrial-cysteine-redox-flexibility-in-mice
#12
Rachel C Kelley, Brian McDonagh, Leonardo F Ferreira
AIM: Inspiratory muscle (diaphragm) function declines with age, contributing to exercise intolerance and impaired airway clearance. Studies of diaphragm dysfunction in rodents have focused on moderate aging (~24months); thus, the impact of advanced age on the diaphragm and potential mechanisms of dysfunction are less clear. Therefore, we aimed to define the effects of advanced age on the mechanics, morphology, and global and redox proteome of the diaphragm. METHODS: We studied diaphragm from young (6months) and very old male mice (30months)...
December 28, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/29282152/safety-and-efficacy-of-inspiratory-muscle-training-for-preventing-adverse-outcomes-in-patients-at-risk-of-prolonged-hospitalisation
#13
Balbino Rivail Ventura Nepomuceno, Mayana de Sá Barreto, Naniane Cidreira Almeida, Caroline Ferreira Guerreiro, Eveline Xavier-Souza, Mansueto Gomes Neto
BACKGROUND: The early institution of inspiratory muscle training on hospitalised patients with no established respiratory deficits could prevent in-hospital adverse outcomes that are directly or indirectly associated to the loss of respiratory muscle mass inherent to a prolonged hospital stay. The objective of the clinical trial is to assess the impact of inspiratory muscle training on hospital inpatient complications. METHODS: This is a double-blind randomised controlled trial...
December 28, 2017: Trials
https://www.readbyqxmd.com/read/29278896/long-term-pulmonary-function-in-duchenne-muscular-dystrophy-comparison-of-eteplirsen-treated-patients-to-natural-history
#14
T Bernard Kinane, Oscar H Mayer, Petra W Duda, Linda P Lowes, Stephanie L Moody, Jerry R Mendell
BACKGROUND: Duchenne muscular dystrophy (DMD) is a rare, degenerative, X-linked genetic disease that results in progressive muscle loss and premature death, most commonly from respiratory or cardiac failure. DMD is primarily caused by whole exon deletions, resulting in a shift of the dystrophin mRNA reading frame that prevents production of functional dystrophin protein. Eteplirsen, a phosphorodiamidate morpholino oligomer (PMO), is designed to skip exon 51, restore the reading frame, and induce production of internally shortened dystrophin in patients with mutations amenable to such treatment...
December 20, 2017: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/29258735/the-effects-of-inspiratory-muscle-training-based-on-the-perceptions-of-patients-with-advanced-lung-disease-a-qualitative-study
#15
Mariana Hoffman, Marcella G Assis, Valéria Maria Augusto, Bruna Mara F Silveira, Verônica F Parreira
BACKGROUND: Advanced lung disease is a chronic non-neoplastic disease that compromises activities of daily living. Treatment includes pulmonary rehabilitation and inspiratory muscle training. Studies have shown the effectiveness of inspiratory muscle training in lung disease patients, but literature is scarce on the patients' perceptions about this topic. OBJECTIVE: To explore the perceptions of patients with advanced lung disease about inspiratory muscle training...
December 8, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/29242088/voluntarily-induced-vomiting-a-yoga-technique-to-enhance-pulmonary-functions-in-healthy-humans
#16
Ragavendrasamy Balakrishnan, Ramesh Mavathur Nanjundaiah, Nandi Krishnamurthy Manjunath
Vomiting is a complex autonomic reflex orchestrated by several neurological centres in the brain. Vagus, the cranial nerve plays a key role in regulation of vomiting. Kunjal Kriya (Voluntarily Induced Vomiting), is a yogic cleansing technique which involves voluntarily inducing vomiting after drinking saline water (5%) on empty stomach. This study was designed with an objective to understand the effect of voluntary induced vomiting (ViV) on pulmonary functions in experienced practitioners and novices and derive its possible therapeutic applications...
December 11, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29238252/the-effect-of-respiratory-muscle-training-on-fin-swimmers-performance
#17
Jana Vašíčková, Kateřina Neumannová, Zbyněk Svozil
Although respiratory muscle functions can influence swimming performance, respiratory muscle training (RMT) is not routinely used for improving fin-swimmers´ performance. The aim of our study was to verify the benefit of a one month of RMT in young fin-swimmers. We assessed the effect of this training on respiratory muscles and on maximal underwater swimming distance. 28 fin-swimmers were randomly divided into an experimental group (EG) and a control group (CG). The study finished with 20 fin-swimmers (EG: n = 12; average age 12...
December 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29237457/the-role-of-src-erk1-2-kinases-in-inspiratory-resistive-breathing-induced-acute-lung-injury-and-inflammation
#18
Dimitrios Toumpanakis, Vyronia Vassilakopoulou, Ioanna Sigala, Panagiotis Zacharatos, Ioanna Vraila, Vassiliki Karavana, Stamatios Theocharis, Theodoros Vassilakopoulos
BACKGROUND: Inspiratory resistive breathing (IRB), a hallmark of obstructive airway diseases, is associated with large negative intrathoracic pressures, due to strenuous contractions of the inspiratory muscles. IRB is shown to induce lung injury in previously healthy animals. Src is a multifunctional kinase that is activated in the lung by mechanical stress. ERK1/2 kinase is a downstream target of Src. We hypothesized that Src is activated in the lung during IRB, mediates ERK1/2 activation and IRB-induced lung injury...
December 13, 2017: Respiratory Research
https://www.readbyqxmd.com/read/29236890/phrenic-nerve-conduction-studies-normative-data-and-technical-aspects
#19
Analucia Abreu Maranhão, Sonia Regina da Silva Carvalho, Marcelo Ribeiro Caetano, Alexandre Hofke Alamy, Eduardo Mesquita Peixoto, Pedro Del Esporte Peçanha Filgueiras
OBJECTIVE: The aim of the present study was to define normative data of phrenic nerve conduction parameters of a healthy population. METHODS: Phrenic nerve conduction studies were performed in 27 healthy volunteers. RESULTS: The normative limits for expiratory phrenic nerve compound muscle action potential were: amplitude (0.47 mv - 0.83 mv), latency (5.74 ms - 7.10 ms), area (6.20 ms/mv - 7.20 ms/mv) and duration (18.30 ms - 20.96 ms). Inspiratory normative limits were: amplitude (0...
December 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/29229110/effects-of-two-types-of-equal-intensity-inspiratory-muscle-training-in-stable-patients-with-chronic-obstructive-pulmonary-disease-a-randomised-controlled-trial
#20
Weiliang Wu, Lili Guan, Xianming Zhang, Xiaoying Li, Yuqiong Yang, Bingpeng Guo, Yonger Ou, Lin Lin, Luqian Zhou, Rongchang Chen
PURPOSE: We conducted a randomised controlled trial to assess the effects of daily breathing pattern changes to stable patients with COPD excluding the confounding factors of inspiratory muscle mobilization, by ensuring the load intensities of two inspiratory training devices were equal. PATIENTS AND METHODS: Sixty patients with COPD were randomised to three groups: resistive-IMT group (T-IMT, 21 patients), threshold-IMT (R-IMT, 19 patients), and a control group (20 patients)...
November 2017: Respiratory Medicine
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