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Inspiratory muscles

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https://www.readbyqxmd.com/read/28931981/immunomodulatory-effects-of-two-different-physical-therapy-modalities-in-patients-with-chronic-obstructive-pulmonary-disease
#1
Sherin Hassan M Mehani
[Purpose] Counteracting the systemic cytokine release and its inflammatory effects by improving respiratory muscle strength and controlling lung inflammation may be important for improving immune system in patients with chronic obstructive pulmonary disease, So the aim of the present study was to evaluate the effect of low level laser therapy and inspiratory muscle training on interleukin-6 (IL-6) as a marker of inflammation and CD4+/CD8+ ratio as a marker for T Lymphocytes in these patients. [Subjects and Methods] Forty male patients with stable COPD participated in the study, their ages ranged between 55-65 years...
September 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28929509/task-dependent-output-of-human-parasternal-intercostal-motor-units-across-spinal-levels
#2
Anna L Hudson, Simon C Gandevia, Jane E Butler
During inspiration, there is differential activity in the human parasternal intercostal muscles across interspaces. We studied if the earlier recruitment of motor units in the rostral interspaces, compared to more caudal spaces, during inspiration is preserved for the non-respiratory task of ipsilateral trunk rotation. Single motor unit activity (SMU) was recorded from the first, second and fourth parasternal interspaces on the right side in five participants in two tasks: resting breathing and 'isometric' axial rotation of the trunk during apnoea...
September 20, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28924353/respiratory-muscle-strength-in-idiopathic-scoliosis-after-training-program
#3
Vera Lúcia Dos Santos Alves, Osmar Avanzi
OBJECTIVE: To analyze the impact of a physiotherapy protocol in maximum inspiratory and expiratory pressure in patients with adolescent idiopathic scoliosis (AIS) by manovacuometry. AIS may change the respiratory dynamics and the performance of inspiratory and expiratory muscles, affecting ventilatory capacity. METHODS: Patients with AIS aged 10 to 20 years old were randomly assigned to receive an aerobic exercise-training program or no treatment. They were evaluated for respiratory muscle strength before and after the treatment period by means of manovacuometry, thorax and spine radiographs...
November 2016: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/28919733/cycle-ergometer-and-inspiratory-muscle-training-offer-modest-benefit-compared-with-cycle-ergometer-alone-a-comprehensive-assessment-in-stable-copd-patients
#4
Kai Wang, Guang-Qiao Zeng, Rui Li, Yu-Wen Luo, Mei Wang, Yu-He Hu, Wen-Hui Xu, Lu-Qian Zhou, Rong-Chang Chen, Xin Chen
BACKGROUND: Cycle ergometer training (CET) has been shown to improve exercise performance of the quadriceps muscles in patients with COPD, and inspiratory muscle training (IMT) may improve the pressure-generating capacity of the inspiratory muscles. However, the effects of combined CET and IMT remain unclear and there is a lack of comprehensive assessment. MATERIALS AND METHODS: Eighty-one patients with COPD were randomly allocated to three groups: 28 received 8 weeks of CET + IMT (combined training group), 27 received 8 weeks of CET alone (CET group), and 26 only received 8 weeks of free walking (control group)...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28917004/critical-illness-associated-diaphragm-weakness
#5
REVIEW
Martin Dres, Ewan C Goligher, Leo M A Heunks, Laurent J Brochard
Diaphragm weakness is highly prevalent in critically ill patients. It may exist prior to ICU admission and may precipitate the need for mechanical ventilation but it also frequently develops during the ICU stay. Several risk factors for diaphragm weakness have been identified; among them sepsis and mechanical ventilation play central roles. We employ the term critical illness-associated diaphragm weakness to refer to the collective effects of all mechanisms of diaphragm injury and weakness occurring in critically ill patients...
September 15, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28916788/a-v0-core-neuronal-circuit-for-inspiration
#6
Jinjin Wu, Paolo Capelli, Julien Bouvier, Martyn Goulding, Silvia Arber, Gilles Fortin
Breathing in mammals relies on permanent rhythmic and bilaterally synchronized contractions of inspiratory pump muscles. These motor drives emerge from interactions between critical sets of brainstem neurons whose origins and synaptic ordered organization remain obscure. Here, we show, using a virus-based transsynaptic tracing strategy from the diaphragm muscle in the mouse, that the principal inspiratory premotor neurons share V0 identity with, and are connected by, neurons of the preBötzinger complex that paces inspiration...
September 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/28916152/effects-of-inspiratory-muscle-training-on-cardiovascular-autonomic-control-a-systematic-review
#7
REVIEW
Raphael Martins de Abreu, Patrícia Rehder-Santos, Vinicius Minatel, Gabriela Lopes Dos Santos, Aparecida Maria Catai
PURPOSE: To carry out a systematic review to determine if inspiratory muscle training (IMT) promotes changes in cardiovascular autonomic responses in humans. METHODS: The methodology followed the PRISMA statement for reporting systematic review analysis. MEDLINE, PEDro, SCOPUS and PubMed electronic databases were searched from the inception to March 2017. The quality assessment was performed using a PEDro scale. The articles were included if: (1) primary objective was related to the effects of IMT on the cardiovascular autonomic nervous system, and (2) randomized clinical trials and quasi-experimental studies...
September 7, 2017: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/28901331/raw-bia-variables-are-predictors-of-muscle-strength-in-patients-with-chronic-obstructive-pulmonary-disease
#8
F de Blasio, M G Santaniello, F de Blasio, G Mazzarella, A Bianco, L Lionetti, F M E Franssen, L Scalfi
BACKGROUND/OBJECTIVES: Although loss of fat-free mass (FFM) and reduced muscle strength are highly prevalent in chronic obstructive pulmonary disease (COPD), only few data are available on the relationships of handgrip strength (HGS) and respiratory muscle strength with body composition in such disease. In particular, we aimed to assess whether raw bioelectrical impedance (BIA) variables were independent predictors of muscle strength in COPD patients, possibly more significant than anthropometric variables and BIA-based estimates of FFM...
September 13, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28894361/effects-of-daily-vitamin-d-supplementation-on-respiratory-muscle-strength-and-physical-performance-in-vitamin-d-deficient-copd-patients-a-pilot-trial
#9
Rachida Rafiq, Hendrik J Prins, Wim G Boersma, Johannes Ma Daniels, Martin den Heijer, Paul Lips, Renate T de Jongh
BACKGROUND: Although vitamin D is well known for its function in calcium homeostasis and bone mineralization, several studies have shown positive effects on muscle strength and physical function. In addition, vitamin D has been associated with pulmonary function and the incidence of airway infections. As vitamin D deficiency is highly prevalent in chronic obstructive pulmonary disease (COPD) patients, supplementation might have a beneficial effect in these patients. OBJECTIVE: To assess the effect of vitamin D supplementation on respiratory muscle strength and physical performance in vitamin D-deficient COPD patients...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28893201/determination-of-the-optimal-inspiratory-pressure-providing-adequate-ventilation-while-minimizing-gastric-insufflation-using-real-time-ultrasonography-in-chinese-children-a-prospective-randomized-double-blind-study
#10
Xiaowei Qian, Qiong Hu, Hang Zhao, Bo Meng, Yang Nan, Hong Cao, Qingquan Lian, Jun Li
BACKGROUND: During facemask ventilation, gastric insufflation is defined as appearance of a comet-tail or an acoustic shadow on ultrasonography. Ultrasonographic measurement of antral cross-section area (CSA) may reflect an insufflated antrum and provide interesting semi-quantitative data in regard to the gastric insufflation. This study aimed to determine the appropriate level of inspiratory pressure sufficient to provide adequate pulmonary ventilation with a lower occurrence of gastric insufflation during facemask pressure-controlled ventilation using real-time ultrasonography in paralyzed children...
September 11, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28890403/sex-differences-in-respiratory-muscle-activation-patterns-during-high-intensity-exercise-in-healthy-humans
#11
Reid A Mitchell, Michele R Schaeffer, Andrew H Ramsook, Sabrina S Wilkie, Jordan A Guenette
Although women experience greater ventilatory constraints and have a higher work of breathing during exercise, they are less susceptible to diaphragm fatigue compared to men. The mechanisms for diaphragmatic fatigue resistance in women is unknown but may be related to sex differences in respiratory muscle recruitment. Accordingly, the purpose of this study was to determine if electromyography (EMG) of the diaphragm (EMGdi) and extra-diaphragmatic inspiratory muscles differ between sexes during exercise. Forty subjects (21M:19F) completed a constant load cycling test at 85% of maximum work rate until exhaustion, while instrumented with an oesophageal electrode catheter to measure EMGdi and surface electrodes to measure EMG of the sternocleidomastoid (EMGscm) and scalene (EMGsca) muscles...
September 7, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28884075/laryngeal-paralysis-associated-with-a-muscle-pseudotumour-in-a-young-dog
#12
Francesca Rizzo, Cecilia Benetti, Consuelo Ballatori, Diana Binanti
An 18-month-old male entire Bloodhound dog was presented with a six-week history of progressive inspiratory dyspnoea, stridor, dysphonia and exercise intolerance. CT scan performed elsewhere had revealed the presence of an unencapsulated nodular mass (3x1x5 cm) dorsal to the larynx and first tracheal rings. Laryngoscopy demonstrated the presence of bilateral laryngeal paralysis and distorted laryngeal architecture suggestive of extraluminal compression. Histopathology results of incisional biopsies from the mass were suggestive of a benign non-neoplastic muscular lesion...
2017: Open veterinary journal
https://www.readbyqxmd.com/read/28877261/myelodysplastic-syndrome-patients-present-more-severe-respiratory-muscle-impairment-and-reduced-forced-vital-capacity-is-disordered-inflammatory-signaling-the-culprit
#13
Bruno Memória Okubo, Anacélia Gomes de Matos, Howard Lopes Ribeiro Junior, Daniela de Paula Borges, Roberta Taiane Germano de Oliveira, Marilena Facundo de Castro, Manoel Ricardo Alves Martins, Romélia Pinheiro Gonçalves, Pedro Felipe Carvalhedo Bruin, Ronald Feitosa Pinheiro, Silvia Maria Meira Magalhães
BACKGROUND/OBJECTIVES: The ageing process is associated with gradual decline in respiratory system performance. Anemia is highly prevalent among older adults and usually associated with adverse outcomes. Myelodysplastic syndromes (MDS) are a heterogeneous group of hematologic malignancies with increasing incidence with age and characterized by anemia and other cytopenias. The main objectives of this study were to evaluate respiratory muscle strength and lung function in elderly patients with anemia, compare data between myelodysplastic syndromes and non-clonal anemias and evaluate the influence of serum IL-8 level and NF-kB activity on deteriorate pulmonary function in this specific population...
2017: PloS One
https://www.readbyqxmd.com/read/28873335/blood-pressure-response-during-normocapnic-hyperpnoea-is-blunted-in-young-women-compared-to-men
#14
Kaori Shimizu, Kanako Goto, Koji Ishida, Mitsuru Saito, Hiroshi Akima, Keisho Katayama
We hypothesized that young women have a lower arterial blood pressure (BP) response to high inspiratory and expiratory muscle contractions with normocapnic hyperpnoea compared to age-matched men. To test this hypothesis, the cardiovascular response during voluntary normocapnic incremental hyperpnoea was evaluated in young women and compared to that of young men. An incremental respiratory endurance test (IRET) was performed as follows: target minute ventilation was initially set to 30% of the maximal voluntary ventilation (MVV12) and was increased by 10% MVV12 every 3min...
September 2, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28862962/inspiratory-muscle-training-is-associated-with-improved-inspiratory-muscle-strength-resting-cardiac-output-and-the-ventilatory-efficiency-of-exercise-in-patients-with-a-fontan-circulation
#15
Karina Laohachai, David Winlaw, Hiran Selvadurai, Ganesh Kumar Gnanappa, Yves d'Udekem, David Celermajer, Julian Ayer
BACKGROUND: Patients with a Fontan circulation have reduced exercise capacity and respiratory muscle strength. Inspiratory muscle training (IMT) improves exercise capacity and quality of life in adults with heart failure. We assessed whether 6 weeks of a home-based program of IMT improves inspiratory muscle strength and the ventilatory efficiency of exercise in adolescent patients with a Fontan circulation. METHODS AND RESULTS: Twenty-three adolescent participants (aged 16±2 years) with a Fontan circulation underwent 6 weeks of IMT for 30 minutes daily...
August 21, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28858191/maximal-respiratory-muscle-strength-and-vital-capacity-in-children-with-early-onset-scoliosis
#16
Gregory Redding, O Henry Mayer, Klane White, Viviana Bompadre, Julia Emerson, Walter Krengel, Robert Campbell
STUDY DESIGN: Descriptive Cross-Sectional Study. OBJECTIVE: To measure respiratory muscle function in children with EOS, determine the frequency of respiratory muscle weakness, and correlate these measures with Vital Capacity, Body Mass Index, and Cobb angle. SUMMARY OF BACKGROUND DATA: Progressive restrictive respiratory disease is common among children with moderate to severe Early Onset Scoliosis (EOS). Reduced respiratory muscle strength is associated with the loss of lung function in adolescents and adults with scoliosis...
August 29, 2017: Spine
https://www.readbyqxmd.com/read/28855461/the-effect-of-expiratory-muscle-strength-training-on-the-oral-and-respiratory-functions-of-community-dwelling-older-people-an-analysis-using-the-swallowing-oral-phonatory-and-respiratory-muscle-function-indices
#17
Naoko Ito, Shuichiro Watanabe
PURPOSE: This study was performed to determine the effects of expiratory muscle strength training (EMST) on the oral and respiratory functions of community-dwelling older people. METHODS: Older people using a visiting-rehabilitation center were divided into an intervention group of 31 subjects and a control group of 15 subjects. Those in the intervention group were assigned home training for 8 weeks, which included 5 sets of 5 breaths per day with a 75% load of the maximum expiratory pressure using an EMST device...
2017: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/28844175/diaphragm-and-intercostal-muscle-activity-following-mid-cervical-spinal-cord-contusion-in-the-rat
#18
Ming-Han Wen, Kun-Ze Lee
The present study was designed to investigate the diaphragm and intercostal muscle activity following unilateral mid-cervical spinal cord contusion in rats. Electromyogram (EMG) activity of the bilateral diaphragm and T2 intercostal muscle was measured in anesthetized and spontaneously breathing rats. Unilateral mid-cervical contusion caused an immediate reduction in inspiratory bursting in the bilateral diaphragm and intercostal muscles. From 3 days to 8 weeks post-contusion, the contused animals displayed significantly lower tidal volume than uninjured animals, regardless of the time point after injury...
August 26, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28839990/short-term-high-intensity-rehabilitation-in-radically-treated-lung-cancer-a-three-armed-randomized-controlled-trial
#19
Jian Huang, Yutian Lai, Xudong Zhou, Shuangjiang Li, Jianhua Su, Mei Yang, Guowei Che
BACKGROUND: The feasibility and practicality of preoperative rehabilitation (PR) programs remains quite controversial in the treatment of lung cancer (LC). This study explored whether a short-term high-intensity rehabilitation program could improve postoperative outcomes compared to those achieved with conventional inspiratory muscle training (IMT). METHODS: A three-armed randomized controlled trial comparing the two training modalities and routine care was conducted in surgical LC patients...
July 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28838325/a-study-on-the-safety-and-efficacy-of-reveglucosidase-alfa-in-patients-with-late-onset-pompe-disease
#20
Barry J Byrne, Tarekegn Geberhiwot, Bruce A Barshop, Richard Barohn, Derralynn Hughes, Drago Bratkovic, Claude Desnuelle, Pascal Laforet, Eugen Mengel, Mark Roberts, Peter Haroldsen, Kristin Reilley, Kala Jayaram, Ke Yang, Liron Walsh
BACKGROUND: Late-onset Pompe disease is a rare genetic neuromuscular disorder caused by lysosomal acid alpha-glucosidase (GAA) deficiency that ultimately results in mobility loss and respiratory failure. Current enzyme replacement therapy with recombinant human (rh)GAA has demonstrated efficacy in subjects with late-onset Pompe disease. However, long-term effects of rhGAA on pulmonary function have not been observed, likely related to inefficient delivery of rhGAA to skeletal muscle lysosomes and associated deficits in the central nervous system...
August 24, 2017: Orphanet Journal of Rare Diseases
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