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https://www.readbyqxmd.com/read/28230150/an-experimental-study-on-the-impacts-of-inspiratory-and-expiratory-muscles-activities-during-mechanical-ventilation-in-ards-animal-model
#1
Xianming Zhang, Juan Du, Weiliang Wu, Yongcheng Zhu, Ying Jiang, Rongchang Chen
In spite of intensive investigations, the role of spontaneous breathing (SB) activity in ARDS has not been well defined yet and little has been known about the different contribution of inspiratory or expiratory muscles activities during mechanical ventilation in patients with ARDS. In present study, oleic acid-induced beagle dogs' ARDS models were employed and ventilated with the same level of mean airway pressure. Respiratory mechanics, lung volume, gas exchange and inflammatory cytokines were measured during mechanical ventilation, and lung injury was determined histologically...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28227820/evaluating-respiratory-muscle-activity-using-a-wireless-sensor-platform
#2
Luis Estrada, Abel Torres, Leonardo Sarlabous, Raimon Jane, Luis Estrada, Abel Torres, Leonardo Sarlabous, Raimon Jane, Raimon Jane, Luis Estrada, Leonardo Sarlabous, Abel Torres
Wireless sensors are an emerging technology that allows to assist physicians in the monitoring of patients health status. This approach can be used for the non-invasive recording of the electrical respiratory muscle activity of the diaphragm (EMGdi). In this work, we acquired the EMGdi signal of a healthy subject performing an inspiratory load test. To this end, the EMGdi activity was captured from a single channel of electromyography using a wireless platform which was compared with the EMGdi and the inspiratory mouth pressure (Pmouth) recorded with a conventional lab equipment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227339/time-frequency-representations-of-the-sternocleidomastoid-muscle-electromyographic-signal-recorded-with-concentric-ring-electrodes
#3
Luis Estrada, Abel Torres, Javier Garcia-Casado, Leonardo Sarlabous, Gema Prats-Boluda, Raimon Jane, Luis Estrada, Abel Torres, Javier Garcia-Casado, Leonardo Sarlabous, Gema Prats-Boluda, Raimon Jane, Luis Estrada, Javier Garcia-Casado, Leonardo Sarlabous, Abel Torres, Gema Prats-Boluda, Raimon Jane
The use of non-invasive methods for the study of respiratory muscle signals can provide clinical information for the evaluation of the respiratory muscle function. The aim of this study was to evaluate time-frequency characteristics of the electrical activity of the sternocleidomastoid muscle recorded superficially by means of concentric ring electrodes (CREs) in a bipolar configuration. The CREs enhance the spatial resolution, attenuate interferences, as the cardiac activity, and also simplify the orientation problem associated to the electrode location...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227300/convolutive-blind-source-separation-on-surface-emg-signals-for-respiratory-diagnostics-and-medical-ventilation-control
#4
Herbert Buchner, Eike Petersen, Marcus Eger, Philipp Rostalski, Herbert Buchner, Eike Petersen, Marcus Eger, Philipp Rostalski, Marcus Eger, Philipp Rostalski, Eike Petersen, Herhert Buchner
The electromyogram (EMG) is an important tool for assessing the activity of a muscle and thus also a valuable measure for the diagnosis and control of respiratory support. In this article we propose convolutive blind source separation (BSS) as an effective tool to pre-process surface electromyogram (sEMG) data of the human respiratory muscles. Specifically, the problem of discriminating between inspiratory, expiratory and cardiac muscle activity is addressed, which currently poses a major obstacle for the clinical use of sEMG for adaptive ventilation control...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28218802/non-invasive-ventilation-for-cystic-fibrosis
#5
REVIEW
Fidelma Moran, Judy M Bradley, Amanda J Piper
BACKGROUND: Non-invasive ventilation may be a means to temporarily reverse or slow the progression of respiratory failure in cystic fibrosis by providing ventilatory support and avoiding tracheal intubation. Using non-invasive ventilation, in the appropriate situation or individuals, can improve lung mechanics through increasing airflow and gas exchange and decreasing the work of breathing. Non-invasive ventilation thus acts as an external respiratory muscle. This is an update of a previously published review...
February 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28212050/volume-controlled-ventilation-does-not-prevent-injurious-inflation-during-spontaneous-effort
#6
Takeshi Yoshida, Susumu Nakahashi, Maria Aparecida Miyuki Nakamura, Yukiko Koyama, Rollin Roldan, Vinicius Torsani, Roberta R De Santis, Susimeire Gomes, Akinori Uchiyama, Marcelo B P Amato, Brian P Kavanagh, Yuji Fujino
RATIONALE: Spontaneous breathing during mechanical ventilation increases transpulmonary pressure and tidal volume, and worsens lung injury. Intuitively, controlling tidal volume and transpulmonary pressure might limit injury from added spontaneous effort. OBJECTIVES: To test the hypothesis that during spontaneous effort in injured lungs, tidal volume and transpulmonary pressure limitation by volume-controlled ventilation results in less injurious patterns of inflation...
February 17, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28210214/arginine-vasopressin-alters-both-spontaneous-and-phase-locked-synaptic-inputs-to-airway-vagal-preganglionic-neuron-via-activation-of-v1a-receptor-insights-into-stress-related-airway-vagal-excitation
#7
Xianxia Yan, Xingxin Chen, Yuhong Guo, Ding He, Yonghua Chen, Chunmei Xia, Jijiang Wang
The airway vagal preganglionic neurons (AVPNs) in the external formation of the nucleus ambiguus (eNA) play a major role in the vagal control of tracheobronchial smooth muscle tone and maintenance of airway resistance. The eNA receives vasopressinergic projection from the hypothalamic paraventricular nucleus (PVN), the key node for the genesis of psychological stress. Since airway vagal excitation is reportedly to be associated with the psychological stress-induced/exacerbated airway hyperresponsiveness in asthmatics, arginine vasopressin (AVP) might be involved in stress-related airway vagal excitation...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28196935/air-stacking-a-detailed-look-into-physiological-acute-effects-on-cough-peak-flow-and-chest-wall-volumes-of-healthy-subjects
#8
Antonio Sarmento, Armèle F Dornelas de Andrade, Íllia Nadinne Df Lima, Andrea Aliverti, Guilherme Augusto de Freitas Fregonezi, Vanessa R Resqueti
BACKGROUND: Air stacking (AS) is a lung insufflation method that requires the use of a manual insufflator to provide air volumes higher than inspiratory capacity. Neuromuscular patients benefit the most from the maneuver; however, the acute effects of AS in healthy subjects are still unclear. METHODS: Twenty healthy subjects (8 males) were studied by optoelectronic plethysmography to investigate the immediate effects of AS on cough peak flow, operational volume variations, distribution of these volumes in the chest wall compartments (pulmonary rib cage, abdominal rib cage, and abdominal), breathing pattern, and shortening velocity of the respiratory muscles during a protocol that included vital capacity maneuvers and spontaneous coughs before and after AS...
February 14, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28194830/parasternal-intercostal-muscle-activity-during-methacholine-induced-bronchoconstriction
#9
Victoria MacBean, Claire L Pringle, Alan C Lunt, Keith D Sharp, Ashraf Ali, Anne Greenough, John Moxham, Gerrard F Rafferty
Neural respiratory drive, measured via the parasternal intercostal electromyogram (EMGpara), provides a non-invasive index of the load-capacity balance of the respiratory muscle pump. Previous studies in patients with obstructive lung disease have shown strong relationships between EMGpara and the extent of both airflow obstruction and hyperinflation. The relative influence of the two factors has not, however, been described. Airflow obstruction was induced via methacholine challenge testing in twenty-five adult humans...
February 14, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28190646/vocal-cord-paralysis-in-charcot-marie-tooth-type-4b1-disease-associated-with-a-novel-mutation-in-the-myotubularin-related-protein-2-gene-a-case-report-and-review-of-the-literature
#10
Alberto Andrea Zambon, Maria Grazia Natali Sora, Giovanna Cantarella, Federica Cerri, Angelo Quattrini, Giancarlo Comi, Stefano Carlo Previtali, Alessandra Bolino
Charcot-Marie-Tooth type 4B1 (CMT4B1) is an autosomal recessive motor and sensory demyelinating neuropathy characterized by the association of early-onset neurological symptoms and typical histological findings. The natural history and the clinical variability of the disease are still poorly known, thus further clarification of the different phenotypes is needed. We report on the case of a Pakistani girl born to consanguineous parents harboring a novel mutation in the MTMR2 gene. When aged 18 months, reduced limb tone, muscle wasting associated with proximal and distal weakness prevalent in lower limbs, absence of tendon reflexes, hoarseness and inspiratory stridor were detected...
January 16, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28181684/exercise-based-cardiac-rehabilitation-for-adults-with-atrial-fibrillation
#11
REVIEW
Signe S Risom, Ann-Dorthe Zwisler, Pernille P Johansen, Kirstine L Sibilitz, Jane Lindschou, Christian Gluud, Rod S Taylor, Jesper H Svendsen, Selina K Berg
BACKGROUND: Exercise-based cardiac rehabilitation may benefit adults with atrial fibrillation or those who had been treated for atrial fibrillation. Atrial fibrillation is caused by multiple micro re-entry circuits within the atrial tissue, which result in chaotic rapid activity in the atria. OBJECTIVES: To assess the benefits and harms of exercise-based rehabilitation programmes, alone or with another intervention, compared with no-exercise training controls in adults who currently have AF, or have been treated for AF...
February 9, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28174465/association-between-respiratory-muscle-strength-and-reduction-of-arterial-blood-pressure-levels-after-aerobic-training-in-hypertensive-subjects
#12
Giovane Galdino, Andreia Maria Silva, José Angelo Bogão, Marcos Paulo Braz de Oliveira, Hayslenne Andressa Gonçalves de Oliveira Araújo, Maísa Sodoco Oliveira, Ana Clara Desiderio Maldonado, Herick Ulisses de Oliveira, Juliana Bassalobre Carvalho Borges
[Purpose] The purpose of present study was associate the increase of respiratory muscle strength with blood pressure levels in hypertensive subjects who underwent an aerobic exercise program. [Subjects and Methods] 90 hypertensive subjects were divided in two groups: intervention and control. All participants had an interview with a physiotherapist and were evaluated by 6-minute walk test, maximal inspiratory pressure, maximal expiratory pressure, heart rate, systolic blood pressure and diastolic blood pressure, before and after the 8 weeks...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28169983/effect-of-preoperative-inspiratory-muscle-training-on-alveolar-arterial-oxygen-gradients-after-coronary-artery-bypass-surgery
#13
Khalid Turky, Amera M Abdelaziz Afify
PURPOSE: Gas exchange abnormalities and inspiratory muscle dysfunction are common postoperative pulmonary complications after cardiac surgery. The aim of this study was to investigate the changes in the alveolar arterial oxygen gradients and inspiratory muscle power after preoperative inspiratory muscle training (IMT) followed by postoperative IMT and early mobilization after coronary artery bypass graft surgery. METHODS: Patients were randomly assigned to the intervention group (n = 20) or the usual care group (n = 20)...
February 6, 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28159632/respiratory-and-locomotor-muscle-implications-on-the-vo2-slow-component-and-the-vo2-excess-in-young-trained-cyclists
#14
Ferid Oueslati, Jan Boone, Zouhair Tabka, Said Ahmaidi
We investigated the impact of ramp and constant-load exercise on (i) respiratory muscle fatigue and locomotor muscle oxygenation, (ii) their relationship with the excess VO2 and VO2 slow component (SC). Fourteen male cyclists performed two tests to exhaustion: an incremental ramp and a constant-load exercise with continuous monitoring of expired gases and oxygenation of the vastus lateralis muscle on two separate days. Maximal inspiratory (MIP) and expiratory (MEP) pressure measurements were taken at rest and post- exercise...
January 31, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28152009/superoxide-dismutase-catalase-mimetic-euk-134-prevents-diaphragm-muscle-weakness-in-monocrotalin-induced-pulmonary-hypertension
#15
Koichi Himori, Masami Abe, Daisuke Tatebayashi, Jaesik Lee, Håkan Westerblad, Johanna T Lanner, Takashi Yamada
Patients with pulmonary hypertension (PH) suffer from inspiratory insufficiency, which has been associated with intrinsic contractile dysfunction in diaphragm muscle. Here, we examined the role of redox stress in PH-induced diaphragm weakness by using the novel antioxidant, EUK-134. Male Wistar rats were randomly divided into control (CNT), CNT + EUK-134 (CNT + EUK), monocrotaline-induced PH (PH), and PH + EUK groups. PH was induced by a single intraperitoneal injection of monocrotaline (60 mg/kg body weight)...
2017: PloS One
https://www.readbyqxmd.com/read/28138234/respiratory-muscle-activity-and-patient-ventilator-asynchrony-during-different-settings-of-noninvasive-ventilation-in-stable-hypercapnic-copd-does-high-inspiratory-pressure-lead-to-respiratory-muscle-unloading
#16
Marieke L Duiverman, Anouk S Huberts, Leo A van Eykern, Gerrie Bladder, Peter J Wijkstra
INTRODUCTION: High-intensity noninvasive ventilation (NIV) has been shown to improve outcomes in stable chronic obstructive pulmonary disease patients. However, there is insufficient knowledge about whether with this more controlled ventilatory mode optimal respiratory muscle unloading is provided without an increase in patient-ventilator asynchrony (PVA). PATIENTS AND METHODS: Ten chronic obstructive pulmonary disease patients on home mechanical ventilation were included...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28137487/inspiratory-muscle-training-during-rehabilitation-in-successfully-weaned-hypercapnic-patients-with-copd
#17
Dominic Dellweg, Karina Reissig, Ekkehard Hoehn, Karsten Siemon, Peter Haidl
BACKGROUND: This study is aimed to evaluate the effect of inspiratory muscle training (IMT) added to rehabilitation in patients with chronic obstructive pulmonary disease (COPD) who remain hypercapnic and use non-invasive ventilation after successful weaning. METHODS: Patients received rehabilitation and were randomized to inspiratory muscle or sham training for 4 weeks. The primary outcome was distance walked within 6 min. Secondary outcomes were inspiratory muscle strength, endurance, lung function, and blood gas levels...
February 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28130844/effect-of-aging-on-hypoxic-exercise-cardiorespiratory-and-muscle-and-cerebral-oxygenation-responses-in-healthy-humans
#18
Lara Puthon, Pierre Bouzat, Paul Robach, Anne Favre-Juvin, Stéphane Doutreleau, Samuel Verges
This study assessed the effects of aging on cardiorespiratory and tissue oxygenation responses to hypoxia both at rest and during incremental maximal exercise. Sixteen young (20 - 30 years) and 15older (60 - 70 years) healthy subjects performed two maximal incremental cycling tests in normoxia and hypoxia (inspiratory oxygen fraction: 12%). Cardiorespiratory responses, prefrontal cortex and quadriceps tissue oxygenation (near infrared spectroscopy) were measured during exercise as well as during hypercapnia at rest...
January 28, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28126479/positive-airway-pressure-therapy-in-heart-failure-patients-long-term-effects-on-lung-function
#19
Henrik Fox, Susanne Witzel, Thomas Bitter, Dieter Horstkotte, Olaf Oldenburg
PURPOSE: The prevalence of sleep-disordered breathing (SDB) in patients with heart failure (HF) is high. Positive airway pressure (PAP) is first-choice therapy, but recent data indicates that PAP therapy may increase mortality in HF patients with reduced ejection fraction (HF-REF) and predominant central sleep apnea (CSA). This study investigated long-term effects of PAP therapy on pulmonary function, including respiratory muscle strength. All patients underwent multichannel cardiorespiratory polysomnography (PSG) and comprehensive lung function testing at baseline and follow-up (mean 588±43days)...
January 23, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28122012/reference-values-for-inspiratory-muscle-endurance-in-healthy-children-and-adolescents
#20
Cristhiele Taís Woszezenki, João Paulo Heinzmann-Filho, Fernanda Maria Vendrusculo, Taila Cristina Piva, Isadora Levices, Márcio Vinícius Fagundes Donadio
AIMS: To generate reference values for two inspiratory muscle endurance (IME) protocols in healthy children and adolescents. MATERIALS AND METHODS: This is an observational, cross-sectional study, in healthy children and adolescents from 4 to 18 years of age. Weight, height, maximal inspiratory pressure (MIP) and IME were measured using two protocols. A fixed load of 30% of MIP with a 10% increment every 2 minutes was used in the incremental threshold loading protocol...
2017: PloS One
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