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https://www.readbyqxmd.com/read/28400507/effects-of-unilateral-airway-occlusion-on-rib-motion-and-inspiratory-intercostal-activity-in-dogs
#1
Dimitri Leduc, Sarah Marechal, Olivier Taton, Bernard Blairon, Alexandre Legrand
Unilateral bronchial occlusion, a complication of many lung diseases, causes dyspnea but the mechanism of this symptom is uncertain. In this study, electromyographic (EMG) activity in the parasternal and external intercostal muscles in the third intercostal space and inspiratory motion of the third rib on both sides of the thorax were assessed during occlusion of a main bronchus for a single breath in anesthetized dogs. Occlusion produced a 65% increase in external intercostal EMG activity in both hemithoraces without altering parasternal EMG activity...
April 2017: Physiological Reports
https://www.readbyqxmd.com/read/28399624/effect-of-respiratory-muscle-training-on-pulmonary-function-and-aerobic-endurance-in-soccer-players
#2
Tarik Ozmen, Gokce Y Gunes, Ilyas Ucar, Hanife Dogan, Tuba U Gafuroglu
BACKGROUND: Few studies investigated the effects of the respiratory muscle training (RMT) in soccer although exhaustive high intensity exercise is known to lead to muscle fatigue in respiratory muscles. The purpose of this study was to investigate the effect of RMT on pulmonary function and aerobic endurance in soccer players. METHODS: Eighteen male soccer players (mean age 22.2±1.4 years) participated in this study. Participants were assigned randomly to either an RMT or a control (CON) group...
May 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28399443/the-effect-of-inspiratory-and-expiratory-loads-on-abdominal-muscle-activity-during-breathing-in-subjects-at-risk-for-the-development-of-chronic-obstructive-pulmonary-disease-and-healthy
#3
António Mesquita Montes, Carlos Crasto, Cristina Argel de Melo, Rita Santos, Susana Pereira, João Paulo Vilas-Boas
The abdominal muscle activity has been shown to be variable in subjects with chronic obstructive pulmonary disease (COPD) when respiratory demand increases and their recruitment pattern may change the mechanics, as well as the work and cost of breathing. The scientific evidence in subjects "at risk" for the development of COPD may be important to understand the natural history of this disease. This study aims to evaluate the effect of inspiratory and expiratory loads on the abdominal muscle activity during breathing in subjects "at risk" for the development of COPD and healthy...
March 31, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28398073/the-link-between-reduced-inspiratory-capacity-and-exercise-intolerance-in-chronic-obstructive-pulmonary-disease
#4
Denis E O'Donnell, Amany F Elbehairy, Katherine A Webb, J Alberto Neder
Low inspiratory capacity (IC), chronic dyspnea and reduced exercise capacity are inextricably linked and are independent predictors of increased mortality in chronic obstructive pulmonary disease (COPD). It is no surprise, therefore, that a major goal of management is to improve IC by reducing lung hyperinflation in order to improve respiratory symptoms and health-related quality of life. The negative effects of lung hyperinflation on respiratory muscle and cardio-circulatory function during exercise are now well established...
April 11, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28394092/reproducibility-of-inspiratory-muscle-endurance-testing-using-powerbreathe-for-copd-patients
#5
Renata P Basso-Vanelli, Valéria A P Di Lorenzo, Mariane Ramalho, Ivana G Labadessa, Eloisa M G Regueiro, Mauricio Jamami, Dirceu Costa
BACKGROUND: Assessing the strength and endurance of respiratory muscles is fundamental for characterizing respiratory muscle dysfunction. Although a variety of tests are used to evaluate respiratory muscle endurance, not all of them are applicable in clinical practice. Assessments can be made using a practical device called PowerBreathe®, but its reproducibility has not been tested in chronic obstructive pulmonary disease (COPD) patients. AIM: To verify the reproducibility of the inspiratory muscle endurance test using a manometer and PowerBreathe® in COPD patients...
April 10, 2017: Physiotherapy Research International: the Journal for Researchers and Clinicians in Physical Therapy
https://www.readbyqxmd.com/read/28389264/the-bulbospinal-network-controlling-the-phrenic-motor-system-laterality-and-course-of-descending-projections
#6
REVIEW
Michael George Zaki Ghali
The respiratory rhythm is generated by the parafacial respiratory group, Bötzinger complex, and pre-Bötzinger complex and relayed to pre-motor neurons, which in turn project to and control respiratory motor outputs in the brainstem and spinal cord. The phrenic nucleus is one such target, containing phrenic motoneurons (PhMNs), which supply the diaphragm, the primary inspiratory muscle in mammals. While some investigators have demonstrated both ipsi- and contralateral bulbophrenic projections, there exists controversy regarding the relative physiological contribution of each to phasic and tonic drive to PhMNs and at which levels decussations occur...
April 4, 2017: Neuroscience Research
https://www.readbyqxmd.com/read/28382660/the-effects-of-threshold-inspiratory-muscle-training-in-patients-with-chronic-obstructive-pulmonary-copd-disease-a-randomized-experimental-study
#7
Han-Yu Chuang, Hsiao Yun Chang, Yueh-Yen Fang, Su-Er Guo
AIMS: To investigate the effects of threshold inspiratory muscle training (IMT) in patients with stages II through IV chronic obstructive pulmonary disease (COPD) using maximum inspiratory pressure (PImax), baseline dyspnoea index (BDI), 6-minute walk test (6MWT), and quality of life (QoL). BACKGROUND: A threshold inspiratory muscle training device provides pressure for inspiratory muscle strength, but there is limited information on the effects of threshold inspiratory muscle training starting at low pressure training...
April 5, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28380186/diaphragmatic-mobility-relationship-with-lung-function-respiratory-muscle-strength-dyspnea-and-physical-activity-in-daily-life-in-patients-with-copd
#8
Flávia Roberta Rocha, Ana Karla Vieira Brüggemann, Davi de Souza Francisco, Caroline Semprebom de Medeiros, Danielle Rosal, Elaine Paulin
Objective: To evaluate diaphragmatic mobility in relation to lung function, respiratory muscle strength, dyspnea, and physical activity in daily life (PADL) in patients with COPD. Methods: We included 25 patients with COPD, classified according to the Global Initiative for Chronic Obstructive Lung Disease criteria, and 25 healthy individuals. For all of the participants, the following were evaluated: anthropometric variables, spirometric parameters, respiratory muscle strength, diaphragmatic mobility (by X-ray), PADL, and the perception of dyspnea...
January 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28378600/addition-of-non-invasive-ventilatory-support-to-combined-aerobic-and-resistance-training-improves-dyspnea-and-quality-of-life-in-heart-failure-patients-a-randomized-controlled-trial
#9
Hugo Souza Bittencourt, Cristiano Gonçalves Cruz, Bruno Costa David, Erenaldo Rodrigues, Camille Magalhães Abade, Roque Aras Junior, Vitor Oliveira Carvalho, Francisco Borges Faria Dos Reis, Mansueto Gomes Neto
OBJECTIVE: To test the hypothesis that combined aerobic and resistance training and non-invasive ventilatory support result in additional benefits compared with combined aerobic and resistance training alone in heart failure patients. DESIGN: A randomized, single-blind, controlled study. SETTING: Cardiac rehabilitation center. PARTICIPANTS: A total of 46 patients with New York Heart Association class II/III heart failure were randomly assigned to a 10-week program of combined aerobic and resistance training, plus non-invasive ventilatory support ( n = 23) or combined aerobic and resistance training alone ( n = 23)...
April 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28373296/a-proteomic-approach-to-identify-alterations-in-the-sumo-network-during-controlled-mechanical-ventilation-in-rat-diaphragm-muscle
#10
Arvind Venkat Namuduri, Gabriel Heras, Jia Mi, Nicola Cacciani, Katarina Hörnaeus, Anne Konzer, Sara Bergström Lind, Lars Larsson, Stefano Gastaldello
The Small Ubiquitin-like Modifier (SUMO) is as a regulator of many cellular functions by reversible conjugation to a broad number of substrates. Under endogenous or exogenous perturbations, the SUMO network becomes a fine sensor of stress conditions by alterations in the expression level of SUMO enzymes and consequently changing the status of SUMOylated proteins. The diaphragm is the major inspiratory muscle, which is continuously active under physiological conditions, but its structure and function is severely affected when passively displaced for long extents during mechanical ventilation (MV)...
April 3, 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/28356632/the-effects-of-inspiratory-diaphragm-breathing-exercise-and-expiratory-pursed-lip-breathing-exercise-on-chronic-stroke-patients-respiratory-muscle-activation
#11
KyoChul Seo, Park Seung Hwan, KwangYong Park
[Purpose] The purpose of this study is to examine the effects of inspiratory diaphragm breathing exercise and expiratory pursed-lip breathing exercise on chronic stroke patients' respiratory muscle activation. [Subjects and Methods] All experimental subjects performed exercises five times per week for four weeks. Thirty chronic stroke patients were randomly assign to an experimental group of 15 patients and a control group of 15 patients. The experimental group underwent exercises consisting of basic exercise treatment for 15 minutes and inspiratory diaphragm breathing exercise and expiratory pursed-lip breathing exercise for 15 minutes and the control group underwent exercises consisting of basic exercise treatment for 15 minutes and auto-med exercise for 15 minutes...
March 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28338488/respiratory-complications-management-and-treatments-for-neuromuscular-disease-in-children
#12
MyMy C Buu
PURPOSE OF REVIEW: To summarize current literature describing the respiratory complications of neuromuscular disease (NMD) and the effect of respiratory interventions and to explore new gene therapies for patients with NMD. RECENT FINDINGS: Measurements of respiratory function focus on vital capacity and maximal inspiratory and expiratory pressure and show decline over time. Management of respiratory complications includes lung volume recruitment, mechanical insufflation-exsufflation, chest physiotherapy and assisted ventilation...
March 23, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28337149/influence-of-inspiratory-muscle-training-on-ventilatory-efficiency-and-cycling-performance-in-normoxia-and-hypoxia
#13
Eduardo Salazar-Martínez, Hannes Gatterer, Martin Burtscher, José Naranjo Orellana, Alfredo Santalla
The aim of this study was to analyse the influence of inspiratory muscle training (IMT) on ventilatory efficiency, in normoxia and hypoxia, and to investigate the relationship between ventilatory efficiency and cycling performance. Sixteen sport students (23.05 ± 4.7 years; 175.11 ± 7.1 cm; 67.0 ± 19.4 kg; 46.4 ± 8.7 ml·kg(-1)·min(-1)) were randomly assigned to an inspiratory muscle training group (IMTG) and a control group (CG). The IMTG performed two training sessions/day [30 inspiratory breaths, 50% peak inspiratory pressure (Pimax), 5 days/week, 6-weeks]...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28318818/twitch-mouth-pressure-for-detecting-respiratory-muscle-weakness-in-suspicion-of-neuromuscular-disorder
#14
Dante Brasil Santos, Gilbert Desmarais, Line Falaize, Adam Ogna, Sandrine Cognet, Bruno Louis, David Orlikowski, Hélène Prigent, Frédéric Lofaso
Twitch mouth pressure using magnetic stimulation of the phrenic nerves and an automated inspiratory trigger is a noninvasive, non-volitional assessment of diaphragmatic strength. Our aims were to validate this method in patients with suspected neuromuscular disease, to determine the best inspiratory-trigger pressure threshold, and to evaluate whether twitch mouth pressure decreased the overdiagnosis of muscle weakness frequently observed with noninvasive volitional tests. Maximal inspiratory pressure, sniff nasal pressure, and twitch mouth pressure were measured in 112 patients with restrictive disease and suspected neuromuscular disorder...
February 2, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28302142/maximum-inspiratory-pressure-as-a-clinically-meaningful-trial-endpoint-for-neuromuscular-diseases-a-comprehensive-review-of-the-literature
#15
REVIEW
Benedikt Schoser, Edward Fong, Tarekegn Geberhiwot, Derralynn Hughes, John T Kissel, Shyam C Madathil, David Orlikowski, Michael I Polkey, Mark Roberts, Harm A W M Tiddens, Peter Young
Respiratory muscle strength is a proven predictor of long-term outcome of neuromuscular disease (NMD), including amyotrophic lateral sclerosis, Duchenne muscular dystrophy, and spinal muscular atrophy. Maximal inspiratory pressure (MIP), a sensitive measure of respiratory muscle strength, one of several useful tests of respiratory muscle strength, is gaining interest as a therapeutic clinical trial endpoint for NMD. In this comprehensive review we investigate the use of MIP as a measure of respiratory muscle strength in clinical trials of therapeutics targeting respiratory muscle, examine the correlation of MIP with survival, quality of life, and other measures of pulmonary function, and outline the role of MIP as a clinically significantly meaningful outcome measure...
March 16, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28288302/whole-body-active-warm-up-and-inspiratory-muscle-warm-up-do-not-improve-running-performance-when-carrying-thoracic-loads
#16
Mark A Faghy, Peter Ian Brown
Whole body active warm ups (AWU) and inspiratory muscle warm up (IMW) prior to exercise improves performance on some endurance exercise tasks. This study investigated the effects of AWU with and without IMW upon 2.4 km running time-trial performance while carrying a 25 kg backpack, a common task and backpack load in physically demanding occupations. Participants (n = 9) performed five 2.4 km running time-trials with a 25 kg thoracic load preceded in random order by 1) IMW comprising 2 x 30 inspiratory efforts against a pressure-threshold load of 40 % maximal inspiratory pressure (PImax), 2) 10 min unloaded running (AWU) at lactate turnpoint (10...
March 13, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28286249/immediate-effects-of-respiratory-muscle-stretching-on-chest-wall-kinematics-and-electromyography-in-copd-patients
#17
Rafaela Barros de Sá, Maíra Florentino Pessoa, Ana Gabriela Leal Cavalcanti, Shirley Lima Campos, César Amorim, Armèle Dornelas de Andrade
This study evaluated the immediate effects of respiratory muscle stretching on chest wall kinematics and electromyographic activity in COPD patients. 28 patients with COPD were randomized into two groups: 14 to the treatment group (TG) and 14 to the control group (CG). The TG underwent a stretching protocol of the rib cage muscles, while the CG remained at rest under similar conditions. After a single session, TG increased the tidal volume of the pulmonary rib cage (Vrcp) (p=0.020) and tidal volume of abdominal rib cage (Vrca) (p=0...
March 10, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28284044/diaphragm-thickness-and-inspiratory-muscle-functions-in-chronic-stroke-patients
#18
Minkyu Kim, Kyeongbong Lee, Jieun Cho, Wanhee Lee
BACKGROUND The aims of this study are to investigate the difference between the diaphragm thickness at end expiration and the thickness at total lung capacity (TLC), and to examine differences in inspiratory muscle function between stroke patients and healthy individuals. MATERIAL AND METHODS Forty-five stroke patients and 49 healthy volunteers were included in this study. Diaphragm thickness was measured at end expiration and at TLC by ultrasonography. The maximal inspiratory pressure (MIP), peak inspiratory flow (PIF), vital capacity (VC), and inspiratory muscle endurance (IME) were assess to evaluate inspiratory muscle function...
March 11, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28281869/clinimetric-properties-of-the-pressure-biofeedback-unit-method-for-estimating-respiratory-pressures
#19
Ana Paula da Silva, Rayele Pricila Moreira Dos Santos, Patrícia Chaves Coertjens, Marcelo Coertjens
OBJECTIVE: The Pressure Biofeedback Unit (PBU) is used to assess the transversus abdominis muscle activity in order to determine the effectiveness of segmental stabilization, but not to verify its accuracy for measuring the pressure values of breathing from transversus abdominis activation. The objective of this study was to cross-validate the PBU pressure evaluated in transversus abdominis muscle activation with the respiratory pressure assessed through manovacuometry in order to verify the extent to which the PBU can be used to indirectly evaluate the strength of the respiratory muscle in both men and women and verify the reliability of the methods...
March 10, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28280321/transdiaphragmatic-pressure-and-neural-respiratory-drive-measured-during-inspiratory-muscle-training-in-stable-patients-with-chronic-obstructive-pulmonary-disease
#20
Weiliang Wu, Xianming Zhang, Lin Lin, Yonger Ou, Xiaoying Li, Lili Guan, Bingpeng Guo, Luqian Zhou, Rongchang Chen
PURPOSE: Inspiratory muscle training (IMT) is a rehabilitation therapy for stable patients with COPD. However, its therapeutic effect remains undefined due to the unclear nature of diaphragmatic mobilization during IMT. Diaphragmatic mobilization, represented by transdiaphragmatic pressure (Pdi), and neural respiratory drive, expressed as the corrected root mean square (RMS) of the diaphragmatic electromyogram (EMGdi), both provide vital information to select the proper IMT device and loads in COPD, therefore contributing to the curative effect of IMT...
2017: International Journal of Chronic Obstructive Pulmonary Disease
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