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https://www.readbyqxmd.com/read/28449462/pulmonary-function-tests-findings-and-their-diagnostic-value-in-patients-with-igg4-related-disease
#1
Lu Cao, Yi-Bing Chen, Da-Hui Zhao, Wen-Fang Shi, Song Meng, Li-Xin Xie
BACKGROUND: IgG4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory disorder that can affect most organs. To date, there have been no detailed assessments of pulmonary function in patients with IgG4-RD. In this study, we investigated pulmonary function in IgG4-RD patients and evaluated the value of pulmonary function tests (PFTs) in diagnosing IgG4-related respiratory disease (IgG4-RRD). METHODS: This was a retrospective study of 17 patients with IgG4-RD...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28448930/determining-equilibrium-partition-coefficients-between-lipid-protein-and-polydimethylsiloxane-for-highly-hydrophobic-organic-contaminants-using-preloaded-disks
#2
Yuanyuan Pei, Huizhen Li, Jing You
Bioaccumulation of hydrophobic organic contaminants is of great concern and understanding their partitioning to biological phases is crucial for estimating their bioaccumulation potential. The estimation, however, was of large uncertainty for highly hydrophobic organic contaminants (HHOCs) with log KOW>9 due to the challenge of quantifying their water concentrations. In the present study, partition coefficients between polydimethylsiloxane (PDMS) and storage lipid (KSL,PDMS), membrane lipid (KML,PDMS) and protein (Kpro,PDMS) were measured for 21 polychlorinated biphenyls (PCBs), 14 polybrominated diphenyl ethers (PBDEs), dechlorane plus (DP) and decabromodiphenyl ethane (DBDPE), covering log KOW from 5...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448817/automated-detection-of-pathologic-white-matter-alterations-in-alzheimer-s-disease-using-combined-diffusivity-and-kurtosis-method
#3
Yuanyuan Chen, Miao Sha, Xin Zhao, Jianguo Ma, Hongyan Ni, Wei Gao, Dong Ming
Diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) are important diffusion MRI techniques for detecting microstructure abnormities in diseases such as Alzheimer's. The advantages of DKI over DTI have been reported generally; however, the indistinct relationship between diffusivity and kurtosis has not been clearly revealed in clinical settings. In this study, we hypothesize that the combination of diffusivity and kurtosis in DKI improves the capacity of DKI to detect Alzheimer's disease compared with diffusivity or kurtosis alone...
April 12, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28444364/effect-of-rituximab-on-the-progression-of-rheumatoid-arthritis-related-interstitial-lung-disease-10-years-experience-at-a-single-centre
#4
Md Yuzaiful Md Yusof, Angela Kabia, Michael Darby, Giovanni Lettieri, Paul Beirne, Edward M Vital, Shouvik Dass, Paul Emery
Objective.: To evaluate the effect of rituximab (RTX) in patients with RA-related interstitial lung disease (RA-ILD) and identify factors associated with outcome after treatment. Methods.: An observational study of patients with RA-ILD was conducted from a cohort of RTX-treated RA patients in a single centre for >10 years. Progression was defined by any of the following: a decrease of pre-RTX forced vital capacity (FVC) >10% or diffusion capacity of carbon monoxide (DLCO) >15% predicted, worsening of the ILD score or death from progressive ILD...
April 24, 2017: Rheumatology
https://www.readbyqxmd.com/read/28443904/na3v2-po4-3-nitrogen-sulfur-codoped-3d-porous-carbon-enabling-ultra-long-cycle-life-sodium-ion-batteries
#5
Yu Jiang, Haochuan Zhang, Hai Yang, Zhenyu Qi, Yan Yu
Na3V2(PO4)3 (NVP) is regarded as a promising cathode material for sodium ion batteries (NIBs) because of its 3D open structure suitable for Na insertion/extraction and high energy density. However, the NVP suffers from poor electrical conductivity, which restricts the rate performance and the long cycle performance of the NVP for NIBs. Here, the NVP particles embedded in the N,S co-doped 3D porous carbon matrix (denoted as NVP@3D-NSC) were prepared by a facile process. The NVP@3D-NSC can deliver high specific discharge capacities at high rates (54 mA h g(-1) at 80 C)...
April 26, 2017: Nanoscale
https://www.readbyqxmd.com/read/28443653/borophane-as-a-bench-mate-of-graphene-a-potential-2d-material-for-anode-of-li-and-na-ion-batteries
#6
Naresh K Jena, Rafael B Araujo, Vivekanand Shukla, Rajeev Ahuja
Borophene, single atomic-layer sheet of boron (Science, 2015, 350, 1513), is a rather new entrant into the burgeoning class of 2D materials. Borophene exhibits anisotropic metallic properties whereas its hydrogenated counterpart borophane is reported to be a gapless Dirac material lying on the same bench with the celebrated graphene. Interestingly, this transition of borophane also rendered stability to it considering the fact that borophene was synthesized under ultra-high vacuum conditions on a metallic (Ag) substrate...
April 26, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28443582/high-resolution-computed-tomography-and-pulmonary-function-findings-of-occupational-arsenic-exposure-in-workers
#7
Recai Ergün, Ender Evcik, Dilek Ergün, Begüm Ergan, Esin Özkan, Özge Gündüz
BACKGROUND: The number of studies where non-malignant pulmonary diseases are evaluated after occupational arsenic exposure are very few. AIMS: The aim of this study is to show the effects of occupational arsenic exposure on the lung by high-resolution computed tomography (HRCT) and pulmonary function tests (PFTs). STUDY DESIGN: Retrospective cross-sectional study. METHODS: In this study 256 workers who were suspected respiratory occupational arsenic exposure are included, having average age 32...
April 6, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28442016/-analysis-of-postoperative-complications-and-risk-factors-of-patients-with-lung-cancer-through-clavien-dindo-classification
#8
Pengfei Li, Yutian Lai, Kun Zhou, Guowei Che
BACKGROUND: Postoperative complications (PCs) are contributing factors to patient mortality following lung resection. In this retrospective study, the Clavien-Dindo classification was used to analyze the current incidence of PCs and identify the risk factors of different grades of PCs. METHODS: A total of 966 lung cancer patients who underwent lobectomy in our department between June 2013 and December 2014 were retrospectively enrolled. Patients were divided into two groups depending on the occurrence of PCs...
April 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/28440389/thermal-behaviour-of-lixmeo2-me-co-or-ni-mn-co-cathode-materials
#9
Petronela Gotcu, Wilhelm Pfleging, Peter Smyrek, Hans J Seifert
Thermal behaviour and thermophysical properties of two typical cathodes for lithium-ion batteries were studied in dependence of temperature. The cathode materials are composite thick films containing a mixture of 90 wt% LiMeO2 active material (with Me = Co or Me = Ni + Mn + Co, respectively) and additives (binder and carbon black), deposited on aluminium current collector foils. The thermal conductivity of each cathode type and their corresponding composite layers were determined up to 573 K from the measured thermal diffusivity, the specific heat capacity and the estimated density based on metallographic methods and structural investigations...
April 25, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28439794/the-effectiveness-of-voriconazole-in-therapy-of-candida-glabrata-s-biofilms-oral-infections-and-its-influence-on-the-matrix-composition-and-gene-expression
#10
Célia F Rodrigues, Bruna Gonçalves, Maria Elisa Rodrigues, Sónia Silva, Joana Azeredo, Mariana Henriques
Candida glabrata is one of most prevalent yeast in fungal infections, especially in immunocompromised patients. Its azole resistance results in a low therapeutic response, particularly when associated with biofilms. The main goal of this work was to study the effectiveness of voriconazole (Vcz) against C. glabrata biofilms oral pathologies, as esophageal or oropharyngeal candidiasis. Antifungal susceptibilities were determined in pre-formed 24-h-biofilms and ERG genes expression was determined by qRT-PCR. Protein quantification was performed using BCA(®) Kit, carbohydrate was estimated according to the Dubois assay and β-1,3 glucans concentration were determined using Glucatell(®) kit...
April 24, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28437067/in-situ-synthesis-of-tungsten-doped-sno2-and-graphene-nanocomposites-for-high-performance-anode-materials-of-lithium-ion-batteries
#11
Shuai Wang, Liyi Shi, Guorong Chen, Chaoqun Ba, Zhuyi Wang, Jiefang Zhu, Yin Zhao, Meihong Zhang, Shuai Yuan
The composite of tungsten-doped SnO2 and reduced graphene oxide was synthesized through a simple one-pot hydrothermal method. According to the structural characterization of the composite, tungsten ions were doped in the unit cells of tin dioxide rather than simply attaching to the surface. Tungsten-doped SnO2 was in-situ growing on the surface of graphene sheet to form a three-dimension conductive network which enhanced the electron transportation and lithium ion diffusion effectively, as well as the issues of SnO2 agglomeration and volume expansion could be avoided because the tungsten-doped SnO2 nanoparticles were homogeneously distributed on graphene sheet...
April 24, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28436600/high-performance-integrated-self-package-flexible-li-o2-battery-based-on-stable-composite-anode-and-flexible-gas-diffusion-layer
#12
Xiao-Yang Yang, Ji-Jing Xu, Di Bao, Zhi-Wen Chang, Da-Peng Liu, Yu Zhang, Xin-Bo Zhang
With the rising development of flexible and wearable electronics, corresponding flexible energy storage devices with high energy density are required to provide a sustainable energy supply. Theoretically, rechargeable flexible Li-O2 batteries can provide high specific energy density; however, there are only a few reports on the construction of flexible Li-O2 batteries. Conventional flexible Li-O2 batteries possess a loose battery structure, which prevents flexibility and stability. The low mechanical strength of the gas diffusion layer and anode also lead to a flexible Li-O2 battery with poor mechanical properties...
April 24, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28432257/excess-diffuse-light-absorption-in-upper-mesophyll-limits-co2-drawdown-and-depresses-photosynthesis
#13
Jeffrey Mason Earles, Guillaume Théroux-Rancourt, Matthew E Gilbert, Andrew J McElrone, Craig Brodersen
In agricultural and natural systems, diffuse light can enhance plant primary productivity due to deeper penetration into and greater illumination of the entire canopy. However, for individual sun-grown leaves from three species, photosynthesis is actually less efficient under diffuse compared to direct light. Despite its potential impact on canopy-level productivity, the mechanism for this leaf-level 'diffuse light photosynthetic depression' effect is unknown. Here we investigate if the spatial distribution of light absorption relative to electron transport capacity in sun- and shade-grown H...
April 21, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28431576/enhanced-neuroinvasion-by-smaller-soluble-prions
#14
Cyrus Bett, Jessica Lawrence, Timothy D Kurt, Christina Orru, Patricia Aguilar-Calvo, Anthony E Kincaid, Witold K Surewicz, Byron Caughey, Chengbiao Wu, Christina J Sigurdson
Infectious prion aggregates can propagate from extraneural sites into the brain with remarkable efficiency, likely transported via peripheral nerves. Yet not all prions spread into the brain, and the physical properties of a prion that is capable of transit within neurons remain unclear. We hypothesized that small, diffusible aggregates spread into the CNS via peripheral nerves. Here we used a structurally diverse panel of prion strains to analyze how the prion conformation impacts transit into the brain. Two prion strains form fibrils visible ultrastructurally in the brain in situ, whereas three strains form diffuse, subfibrillar prion deposits and no visible fibrils...
April 21, 2017: Acta Neuropathologica Communications
https://www.readbyqxmd.com/read/28427687/improved-adsorption-performance-of-nanostructured-composite-by-ultrasonic-wave-optimization-through-response-surface-methodology-isotherm-and-kinetic-studies
#15
Mehdi Dastkhoon, Mehrorang Ghaedi, Arash Asfaram, Alireza Goudarzi, Seyyedeh Maryam Mohammadi, Shaobin Wang
In this work, ultrasound-assisted adsorption of an anionic dye, sunset yellow (SY) and cationic dyes, malachite green (MG), methylene blue (MB) and their ternary dye solutions onto Cu@ Mn-ZnS-NPs-AC from water aqueous was optimized by response surface methodology (RSM) using the central composite design (CCD). The adsorbent was characterized using Field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), Energy-dispersive X-ray spectroscopy (EDX) and EDX mapping images. The effects of various parameters such as pH, sonication time, adsorbent mass and initial concentrations of SY, MG and MB were examined...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28427656/ultrasonically-assisted-removal-of-congo-red-phloxine-b-and-fast-green-fcf-in-ternary-mixture-using-novel-nanocomposite-following-their-simultaneous-analysis-by-derivative-spectrophotometry
#16
Jaleh Pooralhossini, Mehrorang Ghaedi, Mohammad Ali Zanjanchi, Arash Asfaram
In this study dependency of simultaneous adsorption of Congo Red (CR), Phloxine B (BP) and Fast green FCF (FG) onto CuS/ZnS nanocomposites loaded on activated carbon (CuS/ZnS-NCs-AC) to pH, adsorbent mass, sonication time and initial dyes concentration were modeled and optimized, while CuS/ZnS-NCs-AC was identified by XRD, FESEM and EDS analysis. CR, PB and FG concentration determination were undertaken by first and second order derivative spectrophotometry in ternary mixture. According to central composite design (CCD) based on desirability function (DF), the best experimental conditions was set as pH 6...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28427470/pulmonary-hypertension-in-lymphangioleiomyomatosis-prevalence-severity-and-the-role-of-carbon-monoxide-diffusion-capacity-as-a-screening-method
#17
Carolina S G Freitas, Bruno G Baldi, Carlos Jardim, Mariana S Araujo, Juliana Barbosa Sobral, Gláucia I Heiden, Ronaldo A Kairalla, Rogério Souza, Carlos R R Carvalho
BACKGROUND: Lymphangioleiomyomatosis (LAM) is included within group 5 of the current PH classification (unclear multifactorial mechanisms). However, data regarding the occurrence of PH in LAM are scarce. The aims of the study were to describe the prevalence and characteristics of PH in a large cohort of LAM patients with different levels of severity, and to evaluate the role of echocardiography and carbon monoxide diffusion capacity (DLCO) as screening methods for PH in LAM. METHODS: One hundred five LAM patients underwent transthoracic echocardiography, pulmonary function tests (PFTs) and 6-min walk test (6MWT)...
April 20, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28426227/monovalent-vs-divalent-cation-diffusion-in-thiospinel-ti2s4
#18
Patrick Bonnick, Xiaoqi Sun, Ka-Cheong Lau, Chen Liao, Linda F Nazar
Measurement of Li+ and Mg2+ diffusion in the same Ti2S4 thiospinel material in three electrode cells at elevated temperature negates factors of surface area and cell design, allowing the direct comparison of their diffusion coefficients (D). D values were measured using the Galvanic Intermittent Titration Technique (GITT) as a function of both ion concentration (x) and temperature. During discharge at 55 °C, DLi descends gradually from 2×10-8 cm2/s by an order of magnitude over the range 0 < xLi < 1...
April 20, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28425696/granadilla-inspired-structure-design-for-conversion-alloy-reaction-electrode-with-integrated-lithium-storage-behaviors
#19
Chaoji Chen, Linfeng Peng, Yiju Li, Lei Zhang, Jingwei Xiang, Pei Hu, Shijie Cheng, Yunhui Huang, Jia Xie
Conversion/alloy-reaction electrode materials promise much higher energy density than the commonly used ones based on intercalation chemistries. However, the low electronic conductivity, and specially the large volume expansion upon lithiation hinder their practical applications. Here for the first time, a unique granadilla-inspired structure was designed to prepare the conversion/alloy-reaction anode of carbon coated tin/calcium tin oxide (C@void@Sn/CaSnO3) ternary composite. The granadilla-inspired structure ensures the intimate contact between the Sn/CaSnO3 nanoparticles and the carbon matrix, providing not only conductive networks for electron transport and short distance for Li+ diffusion but also effective space for the electrode volume-expansion towards conversion/alloy reaction...
April 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28424548/decreased-levels-of-irisin-a-skeletal-muscle-cell-derived-myokine-are-related-to-emphysema-associated-with-chronic-obstructive-pulmonary-disease
#20
Yukari Sugiyama, Kazuhisa Asai, Kazuhiro Yamada, Yuko Kureya, Naoki Ijiri, Tetsuya Watanabe, Hiroshi Kanazawa, Kazuto Hirata
BACKGROUND: Cigarette smoking-induced oxidant-antioxidant imbalance is a factor that contributes to the pathogenesis of COPD through epithelial cell apoptosis. Irisin is a skeletal muscle cell-derived myokine associated with physical activity. Irisin is also known to decrease oxidant-induced apoptosis in patients with diabetes mellitus. However, the correlation between irisin and emphysema in COPD and its role in epithelial cell apoptosis remains unknown. SUBJECTS AND METHODS: Forty patients with COPD were enrolled in this study...
2017: International Journal of Chronic Obstructive Pulmonary Disease
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