Read by QxMD icon Read


J Danielle Sharpe, Richard S Hopkins, Robert L Cook, Catherine W Striley
BACKGROUND: Traditional influenza surveillance relies on influenza-like illness (ILI) syndrome that is reported by health care providers. It primarily captures individuals who seek medical care and misses those who do not. Recently, Web-based data sources have been studied for application to public health surveillance, as there is a growing number of people who search, post, and tweet about their illnesses before seeking medical care. Existing research has shown some promise of using data from Google, Twitter, and Wikipedia to complement traditional surveillance for ILI...
October 20, 2016: JMIR Public Health and Surveillance
Hannah K Choe, Usama Gergis, Sebastian A Mayer, Himanshu Nagar, Adrienne A Phillips, Tsiporah B Shore, Michael J Smith, Koen van Besien
BACKGROUND: Preliminary evidence indicates that the addition of low dose TBI (2-4 Gy) to reduced intensity conditioning may reduce the rate of relapse in allogeneic stem cell transplants. In very high risk patients receiving combination haploidentical-single unit cord blood transplants, we have added 4 Gy TBI to the widely used fludarabine, melphalan conditioning regimen, in hopes of reducing relapse and decreasing graft rejection. METHODS: We retrospectively reviewed the posttransplant outcomes of patients who underwent haplo-cord SCT between May 2013 and March 2015 and who received fludarabine 30mg/m2 D-7 to -3, melphalan 140mg/m2 D-2, and 2 Gy TBI D-4 and -3...
October 19, 2016: Transplantation
Nicole Navratil
No abstract text is available yet for this article.
October 20, 2016: Lab Animal
Surendra Kumar
BACKROUND: The outbreak of H1N1 virus had previously reported in India during 2009 flu pandemic. In 2015, the outbreak became widespread throughout India. The states of Gujarat and Rajasthan are severely elected. We studied an outbreak of H1N1 Virus in north-west zone of Rajasthan 2015. OBJECTIVE: To demonstrate the current epidemiological scenario of swine flu (H1N1) in north-west zone of Rajasthan with different demographic factors. METHODS: We screened total 6390 patients...
July 2016: Journal of the Association of Physicians of India
Kimberly N Weaver, Michael D Kappelman, Robert S Sandler, Christopher F Martin, Wenli Chen, Kristen Anton, Millie D Long
BACKGROUND: As variation in care has previously been linked to quality, we aimed to describe variations in inflammatory bowel diseases care by gastroenterology (GI) practice setting. METHODS: We performed a cross-sectional study within the Crohn's and Colitis Foundation of America Partners and used bivariate analyses to compare patient characteristics by GI practice setting (GI-academic [GIA], GI-private, or GI-other). Regression models were used to describe the effects of provider type on steroid use, disease activity, and the quality of life...
November 2016: Inflammatory Bowel Diseases
Vahid Aghadadashi, Ali Mehdinia, Saeideh Molaei
Surface sediments (n=17) were collected from 6 sites located in the coasts of the Bushehr Peninsula. ∑16PAH concentrations were in the range of 285.9-1288ngg(-1) dw and the sediments were moderately polluted. Py, Ph, B(a)A and Flu showed >70% of the detected values in order of the mentioned rank. 4-ring PAHs were the dominant compounds and the molecular ratios presented the dominant pyrolytic source. The toxicity of PAHs for sediment dwelling life was averagely equivalent to occurrence of 0.08ngg(-1) of Dioxin in dw of the examined sediments...
October 12, 2016: Marine Pollution Bulletin
Tiziano Gaiotto, Simon E Hufton
Cross-neutralising monoclonal antibodies against influenza hemagglutinin (HA) are of considerable interest as both therapeutics and diagnostic tools. We have recently described five different single domain antibodies (nanobodies) which share this cross-neutralising activity and suggest their small size, high stability, and cleft binding properties may present distinct advantages over equivalent conventional antibodies. We have used yeast display in combination with deep mutational scanning to give residue level resolution of positions in the antibody-HA interface which are crucial for binding...
2016: PloS One
Adelaide R Murray, Rosemary M Caron
BACKGROUND: The American College Health Association's, National College Health Assessment (ACHA's NCHA) estimates 46.1% of college students reported being vaccinated in the last year. OBJECTIVE: 1) To understand the college student's knowledge, attitude, and beliefs in regards to influenza vaccination; 2) To establish recommendations in a population where high risk transmission does not consistently translate into high vaccination rates. METHODS: Utilizing the health belief model (HBM), a cross-sectional study of college student perspectives of influenza vaccination was conducted...
October 14, 2016: International Journal of Adolescent Medicine and Health
Dalit Talmi-Frank, Zeev Altboum, Inna Solomonov, Yael Udi, Diego Adhemar Jaitin, Mordehay Klepfish, Eyal David, Alina Zhuravlev, Hadas Keren-Shaul, Deborah R Winter, Irit Gat-Viks, Michal Mandelboim, Tamar Ziv, Ido Amit, Irit Sagi
Mounting an effective immune response, while also protecting tissue integrity, is critical for host survival. We used a combined genomic and proteomic approach to investigate the role of extracellular matrix (ECM) proteolysis in achieving this balance in the lung during influenza virus infection. We identified the membrane-tethered matrix metalloprotease MT1-MMP as a prominent host-ECM-remodeling collagenase in influenza infection. Selective inhibition of MT1-MMP protected the tissue from infection-related structural and compositional tissue damage...
October 12, 2016: Cell Host & Microbe
K Rajkumar, A Bhattacharya, S David, S Hari Balaji, R Hariharan, M Jayakumar, N Balaji
AIM: This study was conducted to assess the extent of knowledge, awareness, attitude, and risks of zoonotic diseases among livestock owners in Puducherry region. MATERIALS AND METHODS: A total of 250 livestock farmers were selected randomly from eight revenue villages. And each farmer was interviewed with a questionnaire containing both open- and close-ended questions on various aspects of zoonotic diseases, a total of 49 questionnaires were framed to assess the source and transmission of infection to the farmers and to test their knowledge and awareness about zoonotic diseases...
September 2016: Veterinary World
Erika Little, Kathy Yvorchuk-St Jean, William Little, Fortune Sithole, Guy St Jean
Oxybuprocaine hydrochloride ophthalmic solution has been widely used off-label in horses and donkeys, despite lack of data demonstrating efficacy and safety in these species. The objective of this study was to assess anesthetic efficacy of 0.4% oxybuprocaine hydrochloride ophthalmic solution in horses (n = 5) and donkeys (n = 24) and compare the effects with 0.5% proparacaine hydrochloride ophthalmic solution. The baseline corneal touch threshold (CTT) was measured with a Cochet-Bonnet esthesiometer. Donkeys (n = 12) and horses (n = 5) in group A received sterile ophthalmic solutions 0...
October 2016: Canadian Journal of Veterinary Research, Revue Canadienne de Recherche Vétérinaire
Maheswata Sahoo, Lingaraja Jena, Surya Narayan Rath, Satish Kumar
The influenza A (H1N1) virus, also known as swine flu is a leading cause of morbidity and mortality since 2009. There is a need to explore novel anti-viral drugs for overcoming the epidemics. Traditionally, different plant extracts of garlic, ginger, kalmegh, ajwain, green tea, turmeric, menthe, tulsi, etc. have been used as hopeful source of prevention and treatment of human influenza. The H1N1 virus contains an important glycoprotein, known as neuraminidase (NA) that is mainly responsible for initiation of viral infection and is essential for the life cycle of H1N1...
September 2016: Genomics & Informatics
Valentina Clamer, Ilaria Dorigatti, Laura Fumanelli, Caterina Rizzo, Andrea Pugliese
BACKGROUND: Epidemic models are being extensively used to understand the main pathways of spread of infectious diseases, and thus to assess control methods. Schools are well known to represent hot spots for epidemic spread; hence, understanding typical patterns of infection transmission within schools is crucial for designing adequate control strategies. The attention that was given to the 2009 A/H1N1pdm09 flu pandemic has made it possible to collect detailed data on the occurrence of influenza-like illness (ILI) symptoms in two primary schools of Trento, Italy...
October 12, 2016: Theoretical Biology & Medical Modelling
S P Abiramy, K Vengadakrishnan, Priyadharshini, Aishwarya
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
Markus Elsner
No abstract text is available yet for this article.
October 11, 2016: Nature Biotechnology
Ludovic Giloteaux, Maureen R Hanson, Betsy A Keller
BACKGROUND Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) present with profound fatigue, flu-like symptoms, pain, cognitive impairment, orthostatic intolerance, and post-exertional malaise (PEM), and exacerbation of some or all of the baseline symptoms. CASE REPORT We report on a pair of 34-year-old monozygotic twins discordant for ME/CFS, with WELL, the non-affected twin, and ILL, the affected twin. Both twins performed a two-day cardiopulmonary exercise test (CPET), pre- and post-exercise blood samples were drawn, and both provided stool samples for biochemical and molecular analysis...
October 10, 2016: American Journal of Case Reports
Yu Akaishi, Tetsuya Matsumoto, Yoshimi Harada, Yoji Hirayama
As the characteristics and accuracy of rapid influenza detection tests (RIDTs) vary, the development of a high-performance RIDT has been eagerly anticipated. In this study, we evaluated the new RIDT "GOLD SIGN FLU(®)" and the usual RIDT "Quick Navi-Flu(®)" in terms of detecting the influenza viruses A and B antigens in Japanese adults with influenza-like symptoms from December 2013 to March 2014. Among the 123 patients in whom nasopharyngeal swab specimens were collected, 59 tested positive (influenza A, 38; influenza B, 21) by viral isolation as the gold standard method...
October 6, 2016: International Journal of Infectious Diseases: IJID
Enkelejda Havari, Franco Peracchi
We document the association between war-related shocks in childhood and adult outcomes for Europeans born during the first half of the twentieth century. Using a variety of data, at both the macro- and the micro-level, we address the following questions: What are the patterns of mortality among Europeans born during this period? Do war-related shocks in childhood and adolescence help predict adult health, human capital and wellbeing of the survivors? Are there differences by sex, socio-economic status in childhood, and age when the shocks occurred? At the macro-level, we show that the secular trend towards lower mortality was interrupted by dramatic increases in mortality during World War I, the Spanish Flu, the Spanish Civil War, and World War II, and we quantify the size of these mortality shocks...
September 16, 2016: Economics and Human Biology
Bárbara Castro Vieira, Elisa Monteze Bicalho, Sergi Munné-Bosch, Queila Souza Garcia
The relationship between the phytohormones, gibberellin (GA) and abscisic acid (ABA) and light and temperature on seed germination is still not well understood. Here, we investigated the interaction between light, temperature, ABA and GA in seed germination of Vellozia caruncularis, V. intermedia, and V. alutacea. Seeds were incubated in 100 μM solutions of GA (GA3 or GA4 ), ABA and their respective biosynthesis inhibitors (paclobutrazol - PAC, and fluridone - FLU) at two temperatures (25 and 40 °C). Furthermore, endogenous concentrations of active gibberellins (GAs), including GA1 , GA3 and GA4 , and those of ABA were measured in seeds of V...
October 8, 2016: Plant Biology
Wojciech Kwaśniewski, Norbert Stachowicz, Aleksandra Stupak, Anna Kwaśniewska, Anna Goździcka-Jozefiak
Zika virus (HIV) was first identified in 1947 and upto 2007 the infections in humans have been reported sporadically. Currently, the World Health Organization warns that the rapid spread of the virus Zika in both Americas and an increase in the number of children born with microcephaly in these regions begins to be a serious epidemiological problem. Known ways of spreading this RNA virus of the Flaviviridae family is: with blood, sexual, vertical and even breast feeding. Currently used diagnostic tests are not entirely perfect, as they can detect infections by other viruses in this group but they are available in Poland...
2016: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"