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https://www.readbyqxmd.com/read/29053369/effects-of-message-framing-on-influenza-vaccination-understanding-the-role-of-risk-disclosure-perceived-vaccine-efficacy-and-felt-ambivalence
#1
Sungsu Kim, Ivanka Pjesivac, Yan Jin
The current study examined the effects of framing in promotional health messages on intention to vaccinate against seasonal influenza virus. The findings of an experimental study (N = 86) indicated that exposure to both benefits and side effects of vaccination (gain-framed with risk disclosure message) led to lower intention to receive the flu vaccine. This relationship was mediated by both perceived vaccine efficacy and felt ambivalence in a serial order, revealing the underlying psychological mechanisms important for understanding health-related behaviors...
October 20, 2017: Health Communication
https://www.readbyqxmd.com/read/29051697/new-fluphenazine-analogue-with-antimutagenic-and-anti-multidrug-resistance-activity-degradation-profile-and-stability-indicating-method
#2
Agnieszka Sobczak, Artur Teżyk, Joanna Szyndlarewicz, Jan Ziarniak, Piotr Świątek, Wiesław Malinka
Hydrochloride of 10-{2-hydroxy-3-[N,N-bis-(2-hydroxyethyl)amino]propyl}-2-trifluoromethylphenothiazine (Flu-A) is a analogue of neuroleptic fluphenazine. Flu-A exhibits anti-multidrug resistance, antimutagenic, proapoptopic, and cancer-chemopreventive activities in screening studies. To define identity, quality, and purity of new active substance it is necessary to develop a appropriate analytical method and to establish a degradation profile. Thus, a stability-indicating reversed-phase high-performance liquid chromatography method was developed and validated for quantitative determination of Flu-A in the presence of its degradation products generated under stress conditions...
2017: Medicinal Chemistry Research
https://www.readbyqxmd.com/read/29049288/seasonality-in-risk-of-pandemic-influenza-emergence
#3
Spencer J Fox, Joel C Miller, Lauren Ancel Meyers
Influenza pandemics can emerge unexpectedly and wreak global devastation. However, each of the six pandemics since 1889 emerged in the Northern Hemisphere just after the flu season, suggesting that pandemic timing may be predictable. Using a stochastic model fit to seasonal flu surveillance data from the United States, we find that seasonal flu leaves a transient wake of heterosubtypic immunity that impedes the emergence of novel flu viruses. This refractory period provides a simple explanation for not only the spring-summer timing of historical pandemics, but also early increases in pandemic severity and multiple waves of transmission...
October 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/29046022/-prevalence-of-allergic-rhinitis-and-its-symptoms-in-the-school-children-population-of-cuernavaca-morelos-mexico
#4
Eleazar Mancilla-Hernández, Evaristo Víctor Manuel González-Solórzano, Miguel Alejandro Medina-Ávalos, Raúl Humberto Barnica-Alvarado
BACKGROUND: Studies on allergic rhinitis prevalence have found significant variations in their results, even in closely-living populations. OBJECTIVE: To determine and compare the prevalence of allergic rhinitis and its symptoms in schoolchildren from Cuernavaca, Morelos, Mexico. METHODS: Cross-sectional, descriptive study on the prevalence of allergic rhinitis diagnosis and symptoms, where the "Diagnostic questionnaire for epidemiological studies" was used between June and December 2015 in pre-school and primary and secondary school population, after authorization was granted by parents and school authorities...
July 2017: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/29045728/how-do-primary-care-doctors-in-england-and-wales-code-and-manage-people-with-chronic-kidney-disease-results-from-the-national-chronic-kidney-disease-audit
#5
Lois G Kim, Faye Cleary, David C Wheeler, Ben Caplin, Dorothea Nitsch, Sally A Hull
Background: In the UK, primary care records are electronic and require doctors to ascribe disease codes to direct care plans and facilitate safe prescribing. We investigated factors associated with coding of chronic kidney disease (CKD) in patients with reduced kidney function and the impact this has on patient management. Methods: We identified patients meeting biochemical criteria for CKD (two estimated glomerular filtration rates <60 mL/min/1.73 m2 taken >90 days apart) from 1039 general practitioner (GP) practices in a UK audit...
October 16, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29040388/rna-structure-interactions-and-ribonucleoprotein-processes-of-the-influenza-a-virus
#6
Wayne K Dawson, Michal Lazniewski, Dariusz Plewczynski
In one more years, we will 'celebrate' an exact centenary of the Spanish flu pandemic. With the rapid evolution of the influenza virus, the possibility of novel pandemic remains ever a concern. This review covers our current knowledge of the influenza A virus: on the role of RNA in translation, replication, what is known of the expressed proteins and the protein products generated from alternative splicing, and on the role of base pairing in RNA structure. We highlight the main events associated with viral entry into the cell, the transcription and replication process, an export of the viral genetic material from the nucleus and the final release of the virus...
October 10, 2017: Briefings in Functional Genomics
https://www.readbyqxmd.com/read/29040317/economic-benefits-of-sharing-and-redistributing-influenza-vaccines-when-shortages-occurred
#7
Sheng-I Chen
BACKGROUND: Recurrent influenza outbreak has been a concern for government health institutions in Taiwan. Over 10% of the population is infected by influenza viruses every year, and the infection has caused losses to both health and the economy. Approximately three million free vaccine doses are ordered and administered to high-risk populations at the beginning of flu season to control the disease. The government recommends sharing and redistributing vaccine inventories when shortages occur...
2017: PloS One
https://www.readbyqxmd.com/read/29039101/methods-for-analysis-of-nanoparticle-immunosuppressive-properties-in-vitro-and-in-vivo
#8
Timothy M Potter, Barry W Neun, Marina A Dobrovolskaia
Adverse drug effects on the immune system function represent a significant concern in the pharmaceutical industry, because 10-20% of the drug withdrawal from the market is accounted to immunotoxicity. Immunosuppression is one such adverse effect. The traditional immune function test used to estimate materials' immunosuppression is a T-cell-dependent antibody response (TDAR). This method involves a 28 day in vivo study evaluating the animal's antibody titer to a known antigen (KLH) with and without challenge...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29037580/a-cross-sectional-survey-to-evaluate-knowledge-attitudes-and-practices-regarding-seasonal-influenza-and-influenza-vaccination-among-diabetics-in-pretoria-south-africa
#9
Olawale D Olatunbosun, Tonya M Esterhuizen, Charles S Wiysonge
BACKGROUND: In South Africa, influenza vaccination is recommended to all diabetics. However, vaccination coverage among diabetics remains low. Therefore, this study aimed to explore the knowledge, attitudes, and practices among people with diabetes in Pretoria regarding seasonal influenza and influenza vaccination. METHOD: A cross-sectional survey was conducted among type 1 and 2 diabetes mellitus patients who attended diabetic clinics in two major tertiary hospitals in Pretoria, South Africa from October to December 2015...
October 13, 2017: Vaccine
https://www.readbyqxmd.com/read/29036487/prospective-and-retrospective-evaluation-of-the-performance-of-the-fda-approved-cepheid-xpert-flu-rsv-xc-assay
#10
Sophie Arbefeville, Elizabeth Thonen-Kerr, Patricia Ferrieri
Rapid and accurate detection of respiratory viruses is important in patient care and in guiding therapy and infection prevention policy. Rapid viral antigen assays are simple to perform and provide results within 15 to 30 minutes but are limited by their modest-to-moderate sensitivity. Molecular assays are more sensitive and specific but require more technical time and expertise and are more expensive. We verified the performance of the Xpert Flu/RSV XC assay prospectively, using patient respiratory samples from the 2014-2015 respiratory season, and, retrospectively, with frozen patient samples from the previous respiratory season...
September 29, 2017: Laboratory Medicine
https://www.readbyqxmd.com/read/29032272/fludarabine-and-busulfan-versus-fludarabine-cyclophosphamide-and-rituximab-as-reduced-intensity-conditioning-for-allogeneic-transplantation-in-follicular-lymphoma
#11
Narendranath Epperla, Kwang Woo Ahn, Philippe Armand, Samantha Jaglowski, Sairah Ahmed, Vaishalee P Kenkre, Bipin Savani, Madan Jagasia, Nirav N Shah, Timothy S Fenske, Ana Sureda, Sonali M Smith, Mehdi Hamadani
BACKGROUND: Large, multicenter studies comparing commonly used reduced-intensity conditioning (RIC) approaches in follicular lymphoma (FL) have not been performed. Using the CIBMTR database, we report the outcomes of two most commonly used RIC approaches, fludarabine and busulfan (Flu/Bu) vs. fludarabine, cyclophosphamide and rituximab (FCR) in FL patients. METHODS: We evaluated 200 FL patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT) who received RIC with either Flu/Bu (n=98) or FCR (n=102) during 2008-2014...
October 12, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29032268/total-marrow-lymphoid-irradiation-fludarabine-melphalan-tfm-conditioning-for-allogeneic-hematopoietic-cell-transplantation-hct
#12
Lindsay G Jensen, Tracey Stiller, Jeffrey Y C Wong, Joycelynne Palmer, Anthony Stein, Joseph Rosenthal
BACKGROUND: Reduced intensity conditioning regimens (RIC) for hematopoietic stem cell transplantation (HCT) can reduce morbidity and mortality, but patients with advanced disease may require alternate approaches. In an initial report of RIC (Fludarabine (FLU) and Melphalan (MEL)) with total-marrow-lymphoid irradiation (TMLI) in HCT for advanced hematological malignancies in 33 patients, we found the addition of TMLI to RIC was feasible and safe. Here we report long-term outcomes for these patients...
October 12, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29030362/nhs-staff-who-refuse-flu-vaccine-this-winter-will-have-to-give-reasons
#13
Gareth Iacobucci
No abstract text is available yet for this article.
October 13, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29028558/determinants-of-trust-in-the-flu-vaccine-for-african-americans-and-whites
#14
Vicki S Freimuth, Amelia M Jamison, Ji An, Gregory R Hancock, Sandra Crouse Quinn
Trust is thought to be a major factor in vaccine decisions, but few studies have empirically tested the role of trust in adult immunization. Utilizing a 2015 national survey of African American and White adults (n = 1630), we explore multiple dimensions of trust related to influenza immunization, including generalized trust, trust in the flu vaccine, and trust in the vaccine production process. We find African Americans report lower trust than Whites across all trust measures. When considering demographic, racial, and ideological predictors, generalized trust shows statistically significant effects on both trust in the flu vaccine and trust in the vaccine process...
October 4, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29026453/modeling-and-forecasting-influenza-like-illness-ili-in-houston-texas-using-three-surveillance-data-capture-mechanisms
#15
Susannah Paul, Osaro Mgbere, Raouf Arafat, Biru Yang, Eunice Santos
Objective The objective was to forecast and validate prediction estimates of influenza activity in Houston, TX using four years of historical influenza-like illness (ILI) from three surveillance data capture mechanisms. Background Using novel surveillance methods and historical data to estimate future trends of influenza-like illness can lead to early detection of influenza activity increases and decreases. Anticipating surges gives public health professionals more time to prepare and increase prevention efforts...
2017: Online Journal of Public Health Informatics
https://www.readbyqxmd.com/read/29023541/improved-influenza-viral-vector-based-brucella-abortus-vaccine-induces-robust-b-and-t-cell-responses-and-protection-against-brucella-melitensis-infection-in-pregnant-sheep-and-goats
#16
Aigerim Mailybayeva, Bolat Yespembetov, Sholpan Ryskeldinova, Nadezhda Zinina, Abylai Sansyzbay, Gourapura J Renukaradhya, Nikolai Petrovsky, Kaissar Tabynov
We previously developed a potent candidate vaccine against bovine brucellosis caused by Brucella abortus using the influenza viral vector expressing Brucella Omp16 and L7/L12 proteins (Flu-BA). Our success in the Flu-BA vaccine trial in cattle and results of a pilot study in non-pregnant small ruminants prompted us in the current study to test its efficacy against B. melitensis infection in pregnant sheep and goats. In this study, we improved the Flu-BA vaccine formulation and immunization method to achieve maximum efficacy and safety...
2017: PloS One
https://www.readbyqxmd.com/read/29022924/listeriosis-in-pregnancy-under-diagnosis-despite-over-treatment
#17
Y Fouks, S Amit, A Many, A Haham, D Mandel, S Shinar
OBJECTIVE: To compare the symptomatology of pregnant women with suspected listeriosis to culture confirmed listeriosis. STUDY DESIGN: All cases of suspected and culture confirmed pregnancy-associated listeriosis from a single center were retrospectively reviewed assessing demographics, clinical, laboratory and pathological findings, and maternal, fetal and neonatal outcomes. RESULTS: Listeriosis was identified in seven patients, none of whom belonged to the 117 women with suspected listeriosis...
October 12, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29022178/interactive-effects-of-pahs-with-different-rings-and-as-on-their-uptake-transportation-and-localization-in-as-hyperaccumulator
#18
Xiaoyong Liao, Zeying Wu, Xu Ma, Xuegang Gong, Xiulan Yan
In order to illuminate the mechanism of the interaction of polycyclic aromatic hydrocarbon (PAH) with different benzene rings and arsenic (As) in As hyperaccumulator, Pteris vittata L., the uptakes of PAHs were investigated using hydroponics simulation and localizations of PAHs in the plant were determined using two-photon laser scanning confocal microscopy (TPLSCM). The results showed that the total As concentration in different parts of P. vittata decreased in the presence of PAHs with increased numbers of benzene rings: 38...
October 12, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29020489/multiple-evanescent-white-dot-syndrome-following-acute-epstein-barr-virus-infection
#19
Chang-Sue Yang, Ming-Hung Hsieh, Huan-I Su, Yih-Shiuan Kuo
PURPOSE: To investigate the association between multiple evanescent white dot syndrome (MEWDS) and Epstein-Barr (EB) virus infection. METHODS: A prospective, consecutive case series study was performed in patients with the characteristic findings of MEWDS. Patients received EB viral-specific antibody serologic tests. RESULTS: Five cases of MEWDS who had prodromal flu-like symptoms were enrolled, comprising 2 women and 3 men with a mean age of 34...
October 11, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29018030/general-practice-threatens-to-withhold-repeat-prescriptions-until-patients-have-flu-vaccine
#20
Gareth Iacobucci
No abstract text is available yet for this article.
October 10, 2017: BMJ: British Medical Journal
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