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https://www.readbyqxmd.com/read/27910810/production-of-tnf-alpha-ex-vivo-is-predictive-of-an-immune-response-to-flu-vaccination-in-a-frail-elderly-population
#1
Frédéric Bloch, Bénédicte Charmeteau, Michael Tovey, Jean-François Meritet, Corinne Desaint, Odile Launay, Pierre Lebon
OBJECTIVE: To investigate the relationship between the response to influenza vaccination and the ability to produce proinflamatory cytokines in elderly subjects. METHODS: Whole blood samples from 25 elderly subjects collected before influenza vaccination were stimulated with the influenza vaccine in order to evaluate the secretion of five specific cytokines: TNFα, IFNα, IFNγ, IL2 and IL10. The results were correlated with the increased HAI antibody titres two weeks after vaccination...
September 1, 2016: European Cytokine Network
https://www.readbyqxmd.com/read/27902125/story-in-numbers
#2
(no author information available yet)
Public Health England statistics on front-line NHS staff receiving the voluntary flu vaccination this winter.
November 30, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27900909/nurses-feature-in-winter-health-video
#3
(no author information available yet)
NHS England and Public Health England have joined forces to help over 65s, those with long-term health conditions and young children avoid illnesses such as flu and breathing problems this winter.
November 30, 2016: Nursing Older People
https://www.readbyqxmd.com/read/27894283/small-lung-lesions-invisible-under-fluoroscopy-are-located-accurately-by-three-dimensional-localization-technique-on-chest-wall-surface-and-performed-bronchoscopy-procedures-to-increase-diagnostic-yields
#4
Chaosheng Deng, Xiaoming Cao, Dawen Wu, Haibo Ding, Ruixiong You, Qunlin Chen, Linying Chen, Xin Zhang, Qiaoxian Zhang, Yongquan Wu
BACKGROUND: Nowadays, small peripheral pulmonary lesions (PPLs) are frequently detected and the prognosis of lung cancer depends on the early diagnosis. Because of the high fee and requiring specialized training, many advanced techniques are not available in many developing countries and rural districts. METHODS: Three sets of opaque soft copper wires visible under the fluoroscopy (Flu) in the Flu-flexible bronchoscopy (FB) group (n = 24), which determined the three planes of the lesion, were respectively placed firmly on the surface of the chest wall with adhesive tape on the chest wall...
November 29, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27885052/enhanced-protective-responses-to-a-serotype-independent-pneumococcal-vaccine-when-combined-with-an-inactivated-influenza-vaccine
#5
Rachelle Babb, Austen Chen, Abiodun D Ogunniyi, Timothy R Hirst, Ervin E Kara, Shaun R McColl, Mohammed Alsharifi, James C Paton
Streptococcus pneumoniae and influenza are the world's foremost bacterial and viral respiratory pathogens. We have previously described a gamma-irradiated influenza (γ-FLU) vaccine that provides cross-protective immunity against heterosubtypic infections. More recently, we reported a novel non-adjuvanted gamma-irradiated S. pneumoniae (γ-PN) vaccine that elicits serotype-independent protection. Considering the clinical synergism of both pathogens, combination of a serotype-independent pneumococcal vaccine with a broad-spectrum influenza vaccine to protect against both infections would have considerable clinical impact...
November 24, 2016: Clinical Science (1979-)
https://www.readbyqxmd.com/read/27884946/analysis-of-the-caenorhabditis-elegans-innate-immune-response-to-coxiella-burnetii
#6
James M Battisti, Lance A Watson, Myo T Naung, Adam M Drobish, Ekaterina Voronina, Michael F Minnick
The nematode Caenorhabditis elegans is well established as a system for characterization and discovery of molecular mechanisms mediating microbe-specific inducible innate immune responses to human pathogens. Coxiella burnetii is an obligate intracellular bacterium that causes a flu-like syndrome in humans (Q fever), as well as abortions in domesticated livestock, worldwide. Initially, when wild type C. elegans (N2 strain) was exposed to mCherry-expressing C. burnetii (CCB) a number of overt pathological manifestations resulted, including intestinal distension, deformed anal region and a decreased lifespan...
November 24, 2016: Innate Immunity
https://www.readbyqxmd.com/read/27883012/immune-signatures-of-protective-spleen-memory-cd8-t-cells
#7
Lilia Brinza, Sophia Djebali, Martine Tomkowiak, Julien Mafille, Céline Loiseau, Pierre-Emmanuel Jouve, Simon de Bernard, Laurent Buffat, Bruno Lina, Michèle Ottmann, Manuel Rosa-Calatrava, Stéphane Schicklin, Nathalie Bonnefoy, Grégoire Lauvau, Morgan Grau, Mélanie Wencker, Christophe Arpin, Thierry Walzer, Yann Leverrier, Jacqueline Marvel
Memory CD8 T lymphocyte populations are remarkably heterogeneous and differ in their ability to protect the host. In order to identify the whole range of qualities uniquely associated with protective memory cells we compared the gene expression signatures of two qualities of memory CD8 T cells sharing the same antigenic-specificity: protective (Influenza-induced, Flu-TM) and non-protective (peptide-induced, TIM) spleen memory CD8 T cells. Although Flu-TM and TIM express classical phenotypic memory markers and are polyfunctional, only Flu-TM protects against a lethal viral challenge...
November 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27876098/a-look-back-investigating-google-flu-trends-during-the-influenza-a-h1n1-pdm09-pandemic-in-canada-2009-2010
#8
L J Martin
No abstract text is available yet for this article.
November 23, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27872801/-beauty-contest-indicator-of-cognitive-ability-and-free-riding-strategies-results-from-a-scenario-experiment-about-pandemic-flu-immunization
#9
Björn Rönnerstrand
High immunization coverage rates are desirable in order to reduce total morbidity and mortality rates, but it may also provide an incentive for herd immunity free riding strategies. The aim of this paper was to investigate the link between cognitive ability and vaccination intention in a hypothetical scenario experiment about Avian Flu immunization. A between-subject scenario experiment was utilized to examine the willingness to undergo vaccination when the vaccination coverage was proclaimed to be 36, 62 and 88%...
March 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/27861007/nurses-urged-to-get-the-flu-jab
#10
Flavia Munn
The annual drive urging nurses and other healthcare staff to have their free flu vaccination is underway, following a fall in numbers last year.
November 2, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27858785/monitoring-micropollutants-in-the-swist-river-basin
#11
Ekkehard Christoffels, Andrea Brunsch, Jens Wunderlich-Pfeiffer, Franz Michael Mertens
Micropollutant pathways were studied for the Swist river basin (Western Germany). The aim was to verify the effectiveness of a monitoring approach to detect micropollutants entering the river. In a separate sewer system, water was frequently found to be contaminated with micropollutants. Improper connections of sewage canals to the stormwater network seemed to be the cause of pollution. Wastewater treatment plants (WWTPs) exerted the largest influence on micropollutants for the receiving river. During a flu outbreak, antibiotics in the Swist stemming from WWTPs increased remarkably...
November 2016: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/27858585/third-person-effect-and-pandemic-flu-the-role-of-severity-self-efficacy-method-mentions-and-message-source
#12
Hyunmin Lee, Sun-A Park
Within the context of a pandemic flu, this experiment investigated whether source (government officials or physicians), severity condition (high or low), and mention of self-efficacy method (mention present or absent) in H1N1 health news affected participants' (a) perception of media influence on self and others and (b) intentions to get vaccinated. Results found support for third-person effects, and the magnitude of the effects grew with social distance. Main effect of source, as well as interaction effects among the independent variables on third-person effect and vaccination intentions, were also found...
November 18, 2016: Journal of Health Communication
https://www.readbyqxmd.com/read/27856180/sometimes-scientists-get-the-flu-wrong%C3%A2
#13
Matteo Marcantonio, Emily L Pascoe, Frédéric Baldacchino
In an international research environment, accurate communication is vital. However, the scientific literature does not always utilise consistent terminology and the misuse of some expressions in epidemiology is rife. We encourage the correct terms to be used appropriately to avoid confusion between scientists, policy makers, and members of the public.
November 14, 2016: Trends in Parasitology
https://www.readbyqxmd.com/read/27853563/a-data-driven-model-for-influenza-transmission-incorporating-media-effects
#14
Lewis Mitchell, Joshua V Ross
Numerous studies have attempted to model the effect of mass media on the transmission of diseases such as influenza; however, quantitative data on media engagement has until recently been difficult to obtain. With the recent explosion of 'big data' coming from online social media and the like, large volumes of data on a population's engagement with mass media during an epidemic are becoming available to researchers. In this study, we combine an online dataset comprising millions of shared messages relating to influenza with traditional surveillance data on flu activity to suggest a functional form for the relationship between the two...
October 2016: Royal Society Open Science
https://www.readbyqxmd.com/read/27853229/carbon-dioxide-emissions-still-stable-bird-flu-in-europe-and-ligo-restarts
#15
(no author information available yet)
No abstract text is available yet for this article.
November 16, 2016: Nature
https://www.readbyqxmd.com/read/27852818/parents-acute-illnesses-hospitalizations-and-medication-changes-during-the-difficult-first-year-after-infant-or-child-nicu-picu-death
#16
Dorothy Brooten, JoAnne M Youngblut, Carmen Caicedo, Teresa Del Moral, G Patricia Cantwell, Balagangadhar Totapally
BACKGROUND AND OBJECTIVES: Infant/child death is described as a most stressful life event; however, there are few reports of effects on parent physical health during the first year after the death. The study's purpose is to examine the patterns of parent acute illnesses, hospitalizations, and medication changes over 1 to 13 months after neonatal intensive care unit (NICU) or pediatric intensive care unit (PICU) infant/child death in 3 racial/ethnic groups. METHODS: Secondary analyses were conducted with longitudinal data on parent health and functioning 1 to 13 months after infant/child NICU/PICU death...
November 15, 2016: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/27851322/1687-a-flu-storm-a-rare-case-of-thyroid-storm-resulting-from-influenza-a-and-streptococcal-pneumonia
#17
Junad Chowdhury, Vishad Sheth, Asif Abdul Hameed, Ana Maheshwari, Komal Patel, Kruthika Reddy, Milad Kosa, Dominic Valentino
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27848253/role-of-health-care-professionals-in-preventative-activities-and-vaccination-programs-during-outbreaks
#18
Sándor Balogh, Renáta Papp, Csilla Busa, Ágnes Csikós
PURPOSE: The general purpose of TELL ME study was to give an insight into the experiences of European family physicians with management of H1N1 pandemic flu. METHODS: Qualitative research methods (focus group discussions, one-to-one interviews, and online data collection) were used to explore family doctors' opinion and suggestions. Overall 158 family physicians took part in the study from six European countries. RESULTS: Family doctors' most important experience was that the official campaign was not able to compensate negative effects of the mass media...
November 16, 2016: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/27846592/first-flu-is-forever
#19
Cécile Viboud, Suzanne L Epstein
No abstract text is available yet for this article.
November 11, 2016: Science
https://www.readbyqxmd.com/read/27843940/conditioning-with-fludarabine-busulfan-versus-busulfan-cyclophosphamide-is-associated-with-lower-agvhd-and-higher-survival-but-more-extensive-and-long-standing-bone-marrow-damage
#20
Xin He, YongBin Ye, XiaoJun Xu, Jing Wang, YuXian Huang, GuangYang Weng, MingWan Zhang, KunYuan Guo
Acute graft-versus-host disease (aGVHD) is a major complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT) and a major cause of nonrelapse mortality after allo-HSCT. A conditioning regimen plays a pivotal role in the development of aGVHD. To provide a platform for studying aGVHD and evaluating the impact of different conditioning regimens, we established a murine aGVHD model that simulates the clinical situation and can be conditioned with Busulfan-Cyclophosphamide (Bu-Cy) and Fludarabine-Busulfan (Flu-Bu)...
2016: BioMed Research International
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