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https://www.readbyqxmd.com/read/28211265/human-rabies-2016-updates-and-call-for-data
#1
(no author information available yet)
No abstract text is available yet for this article.
17, 2017: Relevé épidémiologique Hebdomadaire
https://www.readbyqxmd.com/read/28202164/manipulating-the-gut-microbiome-to-decrease-uremic-toxins
#2
Rabi Yacoub, Christina M Wyatt
The uremic solute indoxyl sulfate has been associated with increased mortality and other adverse outcomes in patients with chronic kidney disease. In a recent study published in Cell Host & Microbe, Devlin et al. describe a novel approach to alter the production of indoxyl sulfate through manipulation of the gut microbiota. Although this approach is far from clinical application, it may allow investigators to determine the contribution of uremic solutes to disease pathogenesis.
March 2017: Kidney International
https://www.readbyqxmd.com/read/28197407/tribulations-of-the-last-mile-sides-from-a-regional-program
#3
Victor J Del Rio Vilas, Mary J Freire de Carvalho, Marco A N Vigilato, Felipe Rocha, Alexandra Vokaty, Julio A Pompei, Baldomero Molina Flores, Natael Fenelon, Ottorino Cosivi
In Latin American and Caribbean (LAC) countries, the number of cases of dog-mediated human rabies is at its lowest since the onset of the Regional Program for Rabies Elimination in 1983, a commitment from LAC countries to eliminate dog-mediated rabies coordinated by the Pan American Health Organization. Despite minor setbacks, the decline in the number of human cases has been constant since 1983. While many LAC countries have significantly reduced rabies to a level where it is no longer significant public health concern, elimination has proven elusive and pockets of the disease remain across the region...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28193217/measuring-medication-adherence-in-patients-with-incident-hypertension-a-retrospective-cohort-study
#4
Karen L Tang, Hude Quan, Doreen M Rabi
BACKGROUND: Though pharmacy claims data are commonly used to study medication adherence, there remains no standard operational definition for adherence especially for patients on multiple medications. Even when studies use the same terminology, the actual methods of calculating adherence can differ drastically. It is unclear whether the use of different definitions results in different conclusions regarding adherence and associated outcomes. The objective of our study was to compare adherence rates and associations with mortality using different operational definitions of adherence, and using various methods of handling concurrent medication use...
February 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28188732/modeling-the-transmission-dynamics-and-control-of-rabies-in-china
#5
REVIEW
Shigui Ruan
Human rabies was first recorded in ancient China in about 556 BC and is still one of the major public-health problems in China. From 1950 to 2015, 130,494 human rabies cases were reported in Mainland China with an average of 1,977 cases per year. It is estimated that 95% of these human rabies cases are due to dog bites. The purpose of this article is to provide a review about the models, results, and simulations that we have obtained recently on studying the transmission of rabies in China. We first construct a basic susceptible, exposed, infectious, and recovered (SEIR) type model for the spread of rabies virus among dogs and from dogs to humans and use the model to simulate the human rabies data in China from 1996 to 2010...
February 7, 2017: Mathematical Biosciences
https://www.readbyqxmd.com/read/28188373/role-of-systemic-injection-of-rabies-immunoglobulin-in-rabies-vaccination
#6
Weichen Wu, Shuqing Liu, Pengcheng Yu, Xiaoyan Tao, Xuexin Lu, Jianghong Yan, Qian Wang, Zongshen Zhang, Wuyang Zhu
To determine the role of systemic injection of rabies immunoglobulin (RIG) in rabies vaccination, we analyzed the level of antibody against rabies virus in the serum of mice that received various doses of RIG combined with rabies vaccine. Our results indicate that systemic injection of RIG does not contribute detectably to passive or adaptive immunization, suggesting that the main function of RIG in individuals with category III exposure is to neutralize rabies virus via immediate local infiltration of the wound...
February 10, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28187375/a-comparative-study-of-nuclear-8-hydroxyguanosine-expression-in-autoimmune-thyroid-diseases-and-papillary-thyroid-carcinoma-and-its-relationship-with-p53-bcl-2-and-ki-67-cancer-related-proteins
#7
Malek Mseddi, Riadh Ben Mansour, Naourez Gouiia, Fatma Mnif, Rabï Bousselaa, Mohamed Abid, Tahia Boudaouara, Hamadi Attia, Saloua Lassoued
PURPOSE: To investigate whether the oxidative stress is involved in the evolution of Graves' disease (GD) and Hashimoto thyroiditis (HT) into Papillary Thyroid Carcinoma (PTC), 8-hydroxy-2'-deoxyguanosine (8-OHdG) and cancer related proteins (Bcl-2, p53 and Ki-67) expressions were evaluated in these pathologies. PATIENTS AND METHODS: Immunohistochemical method was applied on 25 thyroid tissues. Allred score (AS) serving to evaluate the immunostaining is based on a scale from 0 to 8...
June 22, 2016: Advances in Medical Sciences
https://www.readbyqxmd.com/read/28187114/routine-analysis-of-lipase-in-cyst-fluid-is-unnecessary-and-does-not-help-discriminate-between-nonneoplastic-and-neoplastic-cystic-pancreatic-lesions
#8
Ali Sakhdari, Lloyd Hutchinson, Nancy Vaskas, Marypat Scott, Ediz F Cosar, Rabie Al-Turkmani
No abstract text is available yet for this article.
March 2017: Pancreas
https://www.readbyqxmd.com/read/28186992/autophagy-is-highly-targeted-among-host-comparative-proteomes-during-infection-with-different-virulent-rabv-strains
#9
Ling Li, Hongli Jin, Hualei Wang, Zengguo Cao, Na Feng, Jianzhong Wang, Yongkun Zhao, Xuexing Zheng, Pengfei Hou, Nan Li, Hang Chi, Pei Huang, Cuicui Jiao, Qian Li, Lina Wang, Tiecheng Wang, Weiyang Sun, Yuwei Gao, Changchun Tu, Guixue Hu, Songtao Yang, Xianzhu Xia
Rabies virus (RABV) is a neurotropic virus that causes serious disease in humans and animals worldwide. It has been reported that different RABV strains can result in divergent prognoses in animal model. To identify host factors that affect different infection processes, a kinetic analysis of host proteome alterations in mouse brains infected with different virulent RABV strains was performed using isobaric tags for a relative and absolute quantification (iTRAQ)-liquid chromatography-tandem mass spectrometry (LC-MS/MS) proteomics approach, and this analysis identified 147 differentially expressed proteins (DEPs) between the pathogenic challenge virus standard (CVS)-11 strain and the attenuated SRV9 strain...
February 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28182598/announcement-release-of-national-association-of-state-public-health-veterinarians-2016-compendium-of-animal-rabies-prevention-and-control
#10
(no author information available yet)
The 2016 Compendium of Animal Rabies Prevention and Control was released in the March 1, 2016 issue of the Journal of the American Veterinary Medical Association (1). The Compendium's national recommendations for the prevention and control of animal rabies are intended to serve as a basis for an effective rabies control program in the United States. These recommendations facilitate standardization of control procedures across jurisdictions and are reviewed annually and updated as necessary. This announcement of the recommendations facilitates their adoption by increasing awareness among public health agencies and practitioners and makes more readily available a link to statutes and regulations in certain jurisdictions that refer directly to the Compendium language published in MMWR...
February 10, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28181121/first-confirmation-of-rabies-in-zamfara-state-nigeria-in-a-sheep
#11
Ibrahim Ahmad, Caleb Ayuba Kudi, Muktar Salihu Anka, Ishaya S Tekki
No abstract text is available yet for this article.
February 8, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28179970/atypical-teratoid-rhabdoid-tumor-of-the-sellar-region-in-an-adult-with-long-survival-case-report-and-review-of-the-literature
#12
Mussa Hussain Almalki, Ashjan Alrogi, Abdulkarim Al-Rabie, Sadeq Al-Dandan, Abdullah Altwairgi, Yasser Orz
Atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant central nervous system neoplasm usually diagnosed in young children, although it can occur in adults. Prognosis for AT/RT is poor, with a median survival of 10 - 11 months. We report a rare case of adult sellar and suprasellar AT/RT in a 36-year-old female patient. She was treated with multi-modalities including surgery, chemotherapy and radiation. She markedly improved following treatment with no recurrence in 3 years follow-up. To our knowledge, this is the 11th case of an adult-onset AT/RT in the sellar or suprasellar region with favorable long-term outcome...
March 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28176619/inferior-vena-cava-replacement-in-living-donor-liver-transplant-for-hepatocellular-carcinoma-first-case-report-in-saudi-arabia
#13
Firas Zahr Eldeen, Mohammed Rabie Abdulfatah, Dieter Broering
Living-donor liver transplant for hepatocellular carcinoma located on hepatocaval confluence or in contact with the inferior vena cava is technically challenging, and candidates for this kind of procedure should be carefully selected. It is difficult to rule out major vascular invasion except after hepatectomy and histologic examination; in addition, the possible dissemination of cancer cells during recipient hepatectomy is a considerable risk. Herein, we report the first case in Saudi Arabia of right lobe living-donor liver transplant combined with inferior vena cava reconstruction using cryopreserved iliac vein graft after en bloc resection of the liver with part of the diaphragm, anterior wall of retrohepatic inferior vena cava, and a 5-cm hepatocellular carcinoma in segment 7...
February 7, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28176028/occupational-risks-and-exposures-among-wildlife-health-professionals
#14
Gemina Garland-Lewis, Christopher Whittier, Suzan Murray, Sally Trufan, Peter M Rabinowitz
Most emerging infectious diseases are zoonotic in origin, with wildlife a frequent source of zoonotic disease events. Although individuals with extensive wildlife contact may be at the greatest risk of contracting novel infectious agents, the occupational risk of those working closely with wildlife has not been well studied. This study assessed the occupational exposures among wildlife health professionals working in multiple countries worldwide. An occupational risk survey of past and present exposures was developed and administered online in a confidential manner to wildlife workers recruited through an ongoing international wildlife pathogen surveillance project...
February 7, 2017: EcoHealth
https://www.readbyqxmd.com/read/28175453/171%C3%A2-resurgery-in-craniovertebral-junction-abnormalities
#15
Pavaman Pandit Sindgikar, Kuntal Kanti Das, Awadesh K Jaiswal, Rabi Narayan Sahu, Arun K Srivastava, Anant Mehrotra, Jayesh Chunilal Sardhara, Kamlesh Singh Bhaisora, Sanjay Behari
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28174074/inactivation-of-rabies-virus
#16
Guanghui Wu, David Selden, Anthony R Fooks, Ashley Banyard
Rabies virus is a notifiable pathogen that must be handled in high containment facilities where national and international guidelines apply. For the effective inactivation of rabies virus, a number of reagents were tested. Virkon S (1%) solution caused more than 4log reduction of rabies virus in culture medium supplemented with 10% foetal calf serum within 1min. Isopropyl alcohol (70%) treatment resulted in >3log reduction of rabies virus within 20s when applied at a ratio of 19:1, making it a suitable agent for surface decontamination whereas 70% ethanol was ineffective...
February 5, 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/28174073/development-and-validation-of-sensitive-real-time-rt-pcr-assay-for-broad-detection-of-rabies-virus
#17
Martin Faye, Laurent Dacheux, Manfred Weidmann, Sylvie Audrey Diop, Cheikh Loucoubar, Hervé Bourhy, Amadou Alpha Sall, Ousmane Faye
Rabies virus (RABV) remains one of the most important global zoonotic pathogens. RABV causes rabies, an acute encephalomyelitis associated with a high rate of mortality in humans and animals and affecting different parts of the world, particularly in Asia and Africa. Confirmation of rabies diagnosis relies on laboratory diagnosis, in which molecular techniques such as detection of viral RNA by reverse transcription polymerase chain reaction (RT-PCR) are increasingly being used. In this study, two real-time quantitative RT-PCR assays were developed for large-spectrum detection of RABV, with a focus on African isolates...
February 4, 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/28171552/model-systems-of-dux4-expression-recapitulate-the-transcriptional-profile-of-fshd-cells
#18
Sujatha Jagannathan, Sean C Shadle, Rebecca Resnick, Lauren Snider, Rabi N Tawil, Silvère M van der Maarel, Robert K Bradley, Stephen J Tapscott
No abstract text is available yet for this article.
October 15, 2016: Human Molecular Genetics
https://www.readbyqxmd.com/read/28166482/post-exposure-rabies-prophylaxis-in-humans-exposed-to-animals-in-lublin-province-eastern-poland-in-2012-2015-a-retrospective-study
#19
Joanna Krzowska-Firych, Krzysztof Tomasiewicz, Agata Kozøowska
Rabies continues to be one of the most important viral diseases and remains a significant threat to public health across the globe. The post-exposure prophylaxis in humans can effectively prevent death after exposure to a potentially infected animal. In Poland, recommendations for rabies PEP followed the  national guidelines which recommend that people should receive PEP when bitten by an animal suspected to be infected by rabies. PEP in humans  includes cleansing and disinfecting the wound or point of contact, and administering anti-rabies immunization...
February 6, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28161580/the-ectodomain-of-rabies-virus-glycoprotein-determines-dendritic-cell-activation
#20
Junhua Huang, Yachun Zhang, Ying Huang, Clement W Gnanadurai, Ming Zhou, Ling Zhao, Zhen F Fu
The immune evasion of wild-type (wt) rabies virus (RABV) has been attributed to its glycoprotein (G), particularly to their inefficiency to bind/enter into dendritic cells (DCs). However, the domain responsible for G-mediated DC activation is not clear. In the present study, attempts were made to map the domain(s) on the G involved in differential DC activation using laboratory-adapted and wt viruses. Recombinant RABVs with exchange in each of the structural domains such as signal peptide (sp), ectodomain (et), transmembrane domain (tm), cytoplasmic tail (ct) of the G between wt and laboratory-adapted strains were constructed...
February 1, 2017: Antiviral Research
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