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https://www.readbyqxmd.com/read/27911041/impact-of-rabies-vaccination-history-on-attainment-of-an-adequate-antibody-titre-among-dogs-tested-for-international-travel-certification-israel-2010-2014
#1
B Yakobson, N Taylor, N Dveres, S Rotblat, Ż Spero, E W Lankau, J Maki
Rabies is endemic in wildlife or domestic carnivore populations globally. Infection of domestic dogs is of particular concern in many areas. In regions where domestic animals are at risk of exposure to rabies virus, dogs should be routinely vaccinated against rabies to protect both pet and human populations. Many countries require demonstration of an adequate level of serum rabies neutralizing antibodies to permit entry of dogs during international travel. We analysed rabies titres of dogs seeking travel certification in Israel to assess demographic and vaccine history factors associated with antibody titres below the acceptable threshold for travel certification...
December 2, 2016: Zoonoses and Public Health
https://www.readbyqxmd.com/read/27902338/recombinant-rabies-virus-expressing-il-21-enhances-immunogenicity-through-activation-of-t-follicular-helper-cells-and-germinal-center-b-cells
#2
Yajing Zhang, Ming Zhou, Zhao Wang, Jie Yang, Mingming Li, Kunlun Wang, Min Cui, Huanchun Chen, Zhen F Fu, Ling Zhao
Previous studies have demonstrated that the lack of interleukin-21 (IL-21) signaling could affect specific antibody induction after rabies vaccination. Here, to further investigate the overexpression of IL-21 on the immunogenicity of rabies virus (RABV), a recombinant RABV expressing murine IL-21, designated as LBNSE-IL21, was constructed and evaluated in a mouse model. It was found that mice immunized with LBNSE-IL21 could substantially increase the number of T follicular helper (Tfh) cells and germinal center (GC) B cells but did not enhance dendritic cell (DC) activation...
October 25, 2016: Journal of General Virology
https://www.readbyqxmd.com/read/27894942/-masson-s-haemangioma-an-unusual-cause-of-thoracic-compressive-myelopathy
#3
Bikash Ranjan Behera, Rabi Narayan Panda, Sanjib Mishra, Manmath Kumar Dhir
BACKGROUND: Masson's hemangioma is a rare pathological entity, featuring intravascular papillary endothelial hyperplasia. Although benign, this hemangioma grows to form an expansile compressing mass. This lesion is mostly seen in skin and subcutaneous tissue. Occurrence in neuraxis is rare for this pathological entity. Still rarer is the spinal location with only 5 case reports published till date in medical literature. CASE DESCRIPTION: Here we present a 26 year old male with paraplegia due to extradural compression at D4, D5 level...
November 25, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27893866/ecology-and-demography-of-free-roaming-domestic-dogs-in-rural-villages-near-serengeti-national-park-in-tanzania
#4
Anna M Czupryna, Joel S Brown, Machunde A Bigambo, Christopher J Whelan, Supriya D Mehta, Rachel M Santymire, Felix J Lankester, Lisa J Faust
Free-roaming dogs (Canis lupus familiaris) are of public health and conservation concern because of their potential to transmit diseases, such as rabies, to both people and wildlife. Understanding domestic dog population dynamics and how they could potentially be impacted by interventions, such as rabies vaccination, is vital for such disease control efforts. For four years, we measured demographic data on 2,649 free-roaming domestic dogs in four rural villages in Tanzania: two villages with and two without a rabies vaccination campaign...
2016: PloS One
https://www.readbyqxmd.com/read/27893654/safety-comparison-of-four-types-of-rabies-vaccines-in-patients-with-who-category-ii-animal-exposure-an-observation-based-on-different-age-groups
#5
Jun Peng, Sha Lu, Zhenggang Zhu, Man Zhang, Quan Hu, Yuan Fang
To evaluate the safeties of 4 types of rabies vaccines for patients with WHO category II animal exposure, especially in different age groups.A total of 4000 patients with WHO category II animal exposure were randomly divided into 4 vaccine groups, and were respectively given with Vaccines A, B, C, and D. And subjects in each vaccine group were divided into 4 age groups (≤5, 5-18, 19-60, and ≥60-year-old groups). Then adverse events (including local and systemic ones) were recorded and compared. Consequently, except for Vaccine B, patients under the age of 5 in Groups A, C, and D suffered from more adverse reactions than those in other age groups...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27891499/a-presumptive-case-of-human-rabies-a-rare-survived-case-in-rural-ghana
#6
Paschal Awingura Apanga, John Koku Awoonor-Williams, Michael Acheampong, Matthew Ayamba Adam
Rabies remains endemic in Ghana and continues to pose a major public health threat to humans and animals with a nearly 100% case fatality rate in humans. We report of a presumptive case of human rabies whose survival represents a rare occurrence in rural Ghana and worldwide. Lessons from this case study provide a critically needed focus in helping improve rabies surveillance and case management in Ghana. We report of the survival of a 36-year-old man who developed clinical rabies after he was bitten by his dog, while restraining the dog with a chain...
2016: Frontiers in Public Health
https://www.readbyqxmd.com/read/27891041/spinal-intradural-hydatid-cyst-causing-arachnoiditis-a-rare-etiology-of-cauda-equina-syndrome
#7
Suyash Singh, Jayesh Sardhara, Amit Kumar Singh, Arun Kumar Srivastava, Kamlesh Singh Bhaisora, Kuntal Kanti Das, Anant Mehrotra, Rabi N Sahu, Awadhesh Kumar Jaiswal, Sanjay Behari
This study aims to focus on a rare presentation of spinal hydatid cyst as cauda equine syndrome and misdiagnosed as intradural extramedullary (IDEM) benign lesion on magnetic resonance imaging. In this article, we report a case of spinal hydatid cyst masquerading as IDEM tumor, and intraoperatively, we accidently find clumped granuloma with severe arachnoiditis and hydatid cyst in lumber region, which was present as bilateral S1 radiculopathy with cauda equina syndrome. An 11-year-old boy who presented with symptoms and signs of cauda equina syndrome and planned for surgical excision...
October 2016: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/27889651/effect-of-rabi-splitting-on-the-low-temperature-electron-paramagnetic-resonance-signal-of-anthracite
#8
Ryhor Fedaruk, Roman Strzelczyk, Krzysztof Tadyszak, Siarhei A Markevich, Maria Aldona Augustyniak-Jabłokow
Specific distortions of the EPR signal of bulk anthracite are observed at low temperatures. They are accompanied by variations in the microwave oscillator frequency and are explained by the manifestation of the Rabi splitting due to the strong coupling between electron spins and the cavity, combined with the use of an automatic frequency-control (AFC) system. EPR signals are recorded at negligible saturation in the temperature range of 4-300K with use of the AFC system to keep the oscillator frequency locked to the resonant frequency of the TM110 cylinder cavity loaded with the sample...
November 19, 2016: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/27889225/cost-estimate-and-proposal-for-a-development-impact-bond-for-canine-rabies-elimination-by-mass-vaccination-in-chad
#9
Franziska Anyiam, Monique Lechenne, Rolande Mindekem, Assandi Oussigéré, Service Naissengar, Idriss Oumar Alfaroukh, Celine Mbilo, Daugla Doumagoum Moto, Paul G Coleman, Nicole Probst-Hensch, Jakob Zinsstag
Close to 960,000 humans humans die of rabies each year, most of them in Africa and Asia. Clinical rabies can be prevented by post-exposure prophylaxis (PEP). However, PEP is commonly not available or not affordable in developing countries. Another strategy besides treating exposed humans is the vaccination of vector species. In developing countries, 8.36 vector is the domestic canine, that, once infected, is a serious threat to humans. After a successful mass vaccination of 70% of the dogs in N'Djaména, we report here a cost-estimate for a national rabies elimination campaign for Chad...
November 23, 2016: Acta Tropica
https://www.readbyqxmd.com/read/27887926/geographic-clustering-of-acute-complications-and-sociodemographic-factors-in-adults-with-type-1-diabetes
#10
Sonia Butalia, Alka B Patel, Jeffrey A Johnson, William A Ghali, Doreen M Rabi
OBJECTIVES: To assess the geographic distribution of acute complications in patients with type 1 diabetes in a large urban centre; and to assess the association between acute complications and community-level sociodemographic factors. METHODS: Adults (aged ≥18 years old) with type 1 diabetes and acute complications were identified between 2004 and 2008 by using a diabetes centre clinical database or discharge abstracts for acute complications (diabetic ketoacidosis or hypoglycemia)...
November 23, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27884124/community-based-interventions-to-enhance-knowledge-protective-attitudes-and-behaviors-towards-canine-rabies-results-from-a-health-communication-intervention-study-in-guangxi-china
#11
Hairong Wu, Jiao Chen, Lianbin Zou, Liefeng Zheng, Weichao Zhang, Zhenmu Meng, Ricardo J Soares Magalhaes, Youming Wang, Jingli Kang, Xiangdong Sun
BACKGROUND: In China canine rabies poses a serious public health problem in that human mortality ranks the second highest globally. While rabies health education interventions are advocated by WHO to be critical components of modern rabies control and prevention programs, available studies have not adequately investigated the relative efficacy of their implementation in at-risk populations. This study aims to measure and compare the effect on knowledge and protective behavior towards rabies of health education interventions that include a novel Short Messaging Service via cell phone (SMS) and rabies health information sessions (IS)...
November 24, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27878980/cost-effectiveness-of-mass-dog-vaccination-campaigns-against-rabies-in-flores-island-indonesia
#12
E Wera, M C M Mourits, M M Siko, H Hogeveen
A dynamic deterministic simulation model was developed to determine the cost-effectiveness of different mass dog vaccination strategies against rabies in a dog population representative of a typical village on Flores Island. Cost-effectiveness was measured as public cost per averted dog-rabies case. Simulations started with the introduction of one infectious dog into a susceptible dog population of 399 dogs and subsequently ran for a period of 10 years. The base scenario represented a situation without any control intervention...
November 23, 2016: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/27874010/modified-relaxation-dynamics-and-coherent-energy-exchange-in-coupled-vibration-cavity-polaritons
#13
A D Dunkelberger, B T Spann, K P Fears, B S Simpkins, J C Owrutsky
Coupling vibrational transitions to resonant optical modes creates vibrational polaritons shifted from the uncoupled molecular resonances and provides a convenient way to modify the energetics of molecular vibrations. This approach is a viable method to explore controlling chemical reactivity. In this work, we report pump-probe infrared spectroscopy of the cavity-coupled C-O stretching band of W(CO)6 and the direct measurement of the lifetime of a vibration-cavity polariton. The upper polariton relaxes 10 times more quickly than the uncoupled vibrational mode...
November 22, 2016: Nature Communications
https://www.readbyqxmd.com/read/27872612/systems-biomedicine-of-rabies-delineates-the-affected-signaling-pathways
#14
Sadegh Azimzadeh Jamalkandi, Sayed-Hamidreza Mozhgani, Hamid Gholami Pourbadie, Mehdi Mirzaie, Farshid Noorbakhsh, Behrouz Vaziri, Alireza Gholami, Naser Ansari-Pour, Mohieddin Jafari
The prototypical neurotropic virus, rabies, is a member of the Rhabdoviridae family that causes lethal encephalomyelitis. Although there have been a plethora of studies investigating the etiological mechanism of the rabies virus and many precautionary methods have been implemented to avert the disease outbreak over the last century, the disease has surprisingly no definite remedy at its late stages. The psychological symptoms and the underlying etiology, as well as the rare survival rate from rabies encephalitis, has still remained a mystery...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27871210/para-kala-azar-dermal-leishmaniasis-cases-in-indian-subcontinent-a-case-series
#15
Rakesh Kumar, Vidya Nand Rabi Das, Roshan Kamal Topno, Biplab Pal, Adnan Imam, Kanhaiya Agrawal, Anima Singh, Krishna Murti, Chandra Shekhar Lal, Neena Verma, Pradeep Das, Krishna Pandey
No abstract text is available yet for this article.
November 22, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27870541/rabies-in-poland-in-2013-and-2014
#16
Małgorzata Sadkowska-Todys, Bożena Kucharczyk
OBJECTIVE: Evaluation of the epidemiological situation of rabies in Poland in 2013 and 2014 in comparison to the previous years. MATERIAL AND METHODS: The evaluation was based on analysis of the data from individual report sent by the Epidemiological-Sanitary Stations. The data are from questionnaires of persons who were administered vaccine against rabies following exposure in Poland and beyond its territory, data from annual bulletin “Infectious diseases and poisonings in Poland in 2012-2014”(Czarkowski MP et al...
2016: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/27869922/-healthcare-profile-of-rabies-pre-exposure-prophylaxis-in-the-state-of-rio-grande-do-sul-brazil-2007-2014
#17
Roberta Silva Silveira da Mota, Luiz Filipe Damé Schuch, Dóris Gómez Marcos Schuch, Christieli Prestes Osmari, Tássia Gomes Guimarães
OBJECTIVE: to describe the profile of healthcare provision regarding rabies pre-exposure prophylaxis (RPrEP) in the state of Rio Grande do Sul, Brazil, as compared with the Technical Standards for Rabies Prophylaxis in Humans. METHODS: this was a descriptive study using Notifiable Disease Information System data on anti-rabies healthcare provided between 2007 and 2014. RESULTS: only 2.4% of anti-rabies healthcare related to RPrEP (5,721/239,245), 42...
July 2016: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/27869393/-assessment-of-the-spatial-accessibility-to-the-rabies-vaccination-campaign-in-bogot%C3%A3-colombia
#18
Stefany Monsalve, Santiago Rucinque, Luis Polo, Gina Polo
The access of Bogota's population to health services is unknown, and this hinders the planning of health prevention strategies. Objective: To estimate the spatial accessibility to the vaccination sites of the 2011 campaign against rabies in Bogotá, Colombia, and to compare its efficiency with two other spatial coverage methodologies. Materials and methods: Spatial accessibility was determined using the two-step floating catchment area model (2SFCA). We calculated spatial coverage by establishing circular buffer zones using Euclidean distances, and irregular zones around the vaccination sites using Dijkstra's algorithm on the city's street network...
September 1, 2016: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/27863049/the-epidemiological-importance-of-bats-in-the-transmission-of-rabies-to-dogs-and-cats-in-the-state-of-s%C3%A3-o-paulo-brazil-between-2005-and-2014
#19
J G Castilho, D N de Souza, R N Oliveira, P Carnieli, H B C R Batista, P M C Pereira, S M Achkar, C I Macedo
In Brazil, rabies control in dogs and cats was pioneered by the state of São Paulo with the adoption of the Pan American Health Organization recommendations for prophylaxis and control, which led to a reduction in rabies cases from 1994 onwards. As a result of these measures, the rabies virus (RABV) genetic lineage associated with dogs has not been found in the state since 1998, and all the cases in domestic animals reported since then have been caused by bat-associated lineages of RABV. In the light of this, this study sought to investigate rabies cases in dogs and cats in the state of São Paulo between 2005 and 2014 and identify the associated transmission cycles by characterizing the RABV lineages responsible for these cases...
November 12, 2016: Zoonoses and Public Health
https://www.readbyqxmd.com/read/27863040/a-comparative-study-of-the-rapina-and-the-virus-neutralizing-test-rffit-for-the-estimation-of-antirabies-neutralizing-antibody-levels-in-dog-samples
#20
D L Manalo, K Yamada, I Watanabe, M E G Miranda, S M D Lapiz, E Tapdasan, W Petspophonsakul, S Inoue, P Khawplod, A Nishizono
The mass vaccination of dogs against rabies is a highly rational strategy for interrupting the natural transmission of urban rabies. According to the World Organization for Animal Health (OIE) and the World Health Organization (WHO), the immunization of at least 70% of the total dog population minimizes the risk of endemic rabies. Knowledge of the virus-neutralizing antibody (VNA) level against the rabies virus (RABV) is required to evaluate protective immunity and vaccine coverage of dogs in the field. The rapid focus fluorescent inhibition test (RFFIT) and the fluorescent antibody virus neutralization (FAVN) test are recommended by OIE and WHO to determine the VNA levels in serum...
November 12, 2016: Zoonoses and Public Health
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