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Gold nanoparticles, review

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https://www.readbyqxmd.com/read/28217434/gold-nanoparticle-based-platforms-for-circulating-cancer-marker-detection
#1
Xiaohua Huang, Ryan O'Connor, Elyahb Allie Kwizera
Detection of cancer-related circulating biomarkers in body fluids has become a cutting-edge technology that has the potential to noninvasively screen cancer, diagnose cancer at early stage, monitor tumor progression, and evaluate therapy responses. Traditional molecular and cellular detection methods are either insensitive for early cancer intervention or technically costly and complicated making them impractical for typical clinical settings. Due to their exceptional structural and functional properties that are not available from bulk materials or discrete molecules, nanotechnology is opening new horizons for low cost, rapid, highly sensitive, and highly specific detection of circulating cancer markers...
2017: Nanotheranostics (Syd)
https://www.readbyqxmd.com/read/28217176/biological-mechanisms-of-gold-nanoparticle-radiosensitization
#2
REVIEW
Soraia Rosa, Chris Connolly, Giuseppe Schettino, Karl T Butterworth, Kevin M Prise
There has been growing interest in the use of nanomaterials for a range of biomedical applications over the last number of years. In particular, gold nanoparticles (GNPs) possess a number of unique properties that make them ideal candidates as radiosensitizers on the basis of their strong photoelectric absorption coefficient and ease of synthesis. However, despite promising preclinical evidence in vitro supported by a limited amount of in vivo experiments, along with advances in mechanistic understanding, GNPs have not yet translated into the clinic...
2017: Cancer Nanotechnology
https://www.readbyqxmd.com/read/28198355/in-situ-spectroscopy-of-ligand-exchange-reactions-at-the-surface-of-colloidal-gold-and-silver-nanoparticles
#3
Rebecca Dinkel, Wolfgang Peukert, Björn Braunschweig
Gold and silver nanoparticles with their tunable optical and electronic properties are of great interest for a wide range of applications. Often the ligands at the surface of the nanoparticles have to be exchanged in a second step after particle formation in order to obtain a desired surface functionalization. For many techniques, this process is not accessible in situ. In this review, we present second-harmonic scattering (SHS) as an inherently surface sensitive and label-free optical technique to probe the ligand exchange at the surface of colloidal gold and silver nanoparticles in situ and in real time...
February 15, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28193351/electrochemical-sensors-based-on-magnetic-molecularly-imprinted-polymers-a-review
#4
REVIEW
Paloma Yáñez-Sedeño, Susana Campuzano, José M Pingarrón
Participation of magnetic component in molecularly imprinted polymers (MIPs) has facilitated enormously the incorporation of these polymeric materials on electrode surfaces allowing the design of electrochemical sensors with very attractive analytical characteristics in terms of simplicity, reproducibility, low fabrication cost, high sensitivity and selectivity and rapid assay time. The magnetically susceptible resultant MIPs (MMIPs) allowed a simple and fast elution of the template molecules from MMIPs, are easily and faster collected without filtration, centrifugation or other complex operations and are also faster assembled and removed from the electrode surface by simply using an external magnetic field...
April 1, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28182823/how-to-direct-the-neuronal-growth-process-in-peripheral-nerve-regeneration-future-strategies-for-nanosurfaces-scaffold-and-magnetic-nanoparticles
#5
Andrea Poggetti, Pietro Battistini, Paolo Domenico Parchi, Michela Novelli, Simona Raffa, Marco Cecchini, Anna Maria Nucci, Michele Lisanti
Currently, the gold standard to repair large nerve defects is the autologous nerve graft. These solutions offer a mechanical support, adhesion substrates, and, with Schwann cells (SC), a source of neurotropic factors for axonal growth. The technical limits are the donor side damage, multiple surgical accesses, and the unavailability of large amounts of grafts. In recent years, several researchers focused their attention on the interaction between cells (nervous and glial) and physic-chemical cues that arise from the extracellular milieu...
February 7, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28176270/polymers-in-the-co-delivery-of-sirna-and-anticancer-drugs-for-the-treatment-of-drug-resistant-cancers
#6
REVIEW
Haotian Sun, Iven Yarovoy, Meghan Capeling, Chong Cheng
Recently, co-delivery of siRNA and anticancer drugs has drawn much attention in the treatment of drug-resistant cancers. Drug resistance is exhibited by cancer cells, which limits the efficacy of chemotherapy. When siRNA and anticancer drugs are delivered into cancer cells simultaneously, the siRNA is expected to silence the genes related to drug resistance, decreasing the drug efflux pumps and activating the cell's apoptosis pathways. In a timeframe following the release of siRNA, the accumulation of the co-delivered anti-cancer drug inside of the cancer cells will increase, resulting in promoted chemotherapeutic effects...
April 2017: Topics in Current Chemistry (Journal)
https://www.readbyqxmd.com/read/28163981/current-advances-in-5-aminolevulinic-acid-mediated-photodynamic-therapy
#7
Connor Thunshelle, Rui Yin, Qiquan Chen, Michael R Hamblin
Kennedy and Pottier discovered that photodynamic therapy (PDT) could be carried out using a procedure consisting of topical application of the porphyrin-precursor, 5-aminolevulinic acid (ALA) to the skin, followed after some time by illumination with various light parameters in the 1980s. Since then, ALA-PDT has expanded enormously and now covers most aspects of dermatological disease. The purpose of this review is to discuss a range of ingenious strategies that investigators have devised for improving the overall outcome (higher efficiency and lower side effects) of ALA-PDT...
September 2016: Current Dermatology Reports
https://www.readbyqxmd.com/read/28159216/recent-advances-in-plant-mediated-engineered-gold-nanoparticles-and-their-application-in-biological-system
#8
REVIEW
Khwaja Salahuddin Siddiqi, Azamal Husen
For biosynthesis of gold nanoparticles different parts of a plant are used as they contain metabolites such as alkaloids, flavonoids, phenols, terpenoids, alcohols, sugars and proteins which act as reducing agents to produce nanoparticles. They also act as capping agent and stabilizer for them. They are used in medicine, agriculture and many other technologies. The attention is therefore focussed on all plant species which have either aroma or colour in their leaves, flowers or roots for the synthesis of nanoparticles because they all contain such chemicals which reduce the metal ions to metal nanoparticles...
March 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28150203/methods-for-generation-and-detection-of-nonstationary-vapor-nanobubbles-around-plasmonic-nanoparticles
#9
Ekaterina Y Lukianova-Hleb, Dmitri O Lapotko
Laser pulse-induced vapor nanobubbles are nonstationary nanoevents that offer a broad range of applications, especially in the biomedical field. Plasmonic (usually gold) nanoparticles have the highest energy efficacy of the generation of vapor nanobubbles and such nanobubbles were historically named as plasmonic nanobubbles. Below we review methods (protocols) for generating and detecting plasmonic nanobubbles in liquids. The biomedical applications of plasmonic nanobubbles include in vivo and in vitro detection and imaging, gene transfer, micro-surgery, drug delivery, and other diagnostic, therapeutic, and theranostic applications...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28142120/nanotechnology-for-delivery-of-gemcitabine-to-treat-pancreatic-cancer
#10
REVIEW
Gebremariam Birhanu, Hamid Akbari Javar, Ehsan Seyedjafari, Ali Zandi-Karimi
Pancreatic cancer (PC) is one of the most deadly and quickly fatal human cancers with a 5-year mortality rate close to 100%. Its prognosis is very poor, mainly because of its hostile biological behavior and late onset of symptoms for clinical diagnosis; these bring limitations on therapeutic interventions. Factors contributing for the difficulties in treating PC include: high rate of drug resistance, fast metastasis to different organs, poor prognosis and relapse of the tumor after therapy. After being approved by US FDA 1997, Gemcitabine (Gem) is the first line and the gold standard drug for all stages of advanced PC till now...
January 28, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28095686/characterizing-self-assembled-monolayers-on-gold-nanoparticles
#11
Elena Colangelo, Joan Comenge, David Paramelle, Martin Volk, Qiubo Chen, Raphaël Lévy
A key aspect of nanoscience is to control the assembly of complex materials from a "bottom-up" approach. The self-assembly and self-organization of small ligands at the surface of nanoparticles represent a possible starting route for the preparation of (bio)nanomaterials with precise (bio)physical and (bio)chemical properties. However, surface characterization and elucidation of the structure-properties relationship, essential to envisioning such control, remain challenging and are often poorly investigated...
January 18, 2017: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/28095685/amphiphilic-polymer-guided-plasmonic-assemblies-and-their-biomedical-applications
#12
Jibin Song, Gang Niu, Xiaoyuan Chen
Plasmonic nanostructures with unique physical and biological properties have attracted increased attention for potential biomedical applications. Polymers grafted on metal nanoparticle surface can be used as assembly regulating molecules to guide nanoparticles organize into ordered or hierarchical structures in solution, within condensed phases, or at interfaces. In this Topical Review, we will highlight recent efforts on self-assembly of gold nanoparticles coated with polymer brushes. How and what kind of polymer graft can be used to adjust nanoparticle interactions, to dictate interparticle orientation, and to determine assembled nanostructures will be discussed...
January 18, 2017: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/28095116/recent-progress-on-the-development-of-anisotropic-gold-nanoparticles-design-strategies-and-growth-mechanism
#13
Stacy Jones, Avijit Pramanik, Carrie Sweet, Anthony Keyes, Salma Begum, Aruna Vangra, Hongtal Yu, Peter P Fu, Paresh Chandra Ray
This review summarizes recent advances on design strategies for shape-controlled anisotropic gold nanoparticles. Detailed chemical mechanism has been discussed to understand the anisotropic growth. The effect of various chemical parameters and surface facets for the formation of different shaped anisotropic nanoparticles have been addressed.
January 2, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/28094243/linear-and-ultrafast-nonlinear-plasmonics-of-single-nano-objects
#14
Aurélien Crut, Paolo Maioli, Fabrice Vallée, Natalia Del Fatti
Single-particle optical investigations have greatly improved our understanding of the fundamental properties of nano-objects, avoiding the spurious inhomogeneous effects that affect ensemble experiments. Correlation with high-resolution imaging techniques providing morphological information (e.g. electron microscopy) allows a quantitative interpretation of the optical measurements by means of analytical models and numerical simulations. In this topical review, we first briefly recall the principles underlying some of the most commonly used single-particle optical techniques: near-field, dark-field, spatial modulation and photothermal microscopies/spectroscopies...
March 29, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28068053/surface-modification-of-gold-nanoparticles-with-small-molecules-for-biochemical-analysis
#15
Yiping Chen, Yunlei Xianyu, Xingyu Jiang
As one of the major tools for and by chemical science, biochemical analysis is becoming increasingly important in fields like clinical diagnosis, food safety, environmental monitoring, and the development of chemistry and biochemistry. The advancement of nanotechnology boosts the development of analytical chemistry, particularly the nanoparticle (NP)-based approaches for biochemical assays. Functional NPs can greatly improve the performance of biochemical analysis because they can accelerate signal transduction, enhance the signal intensity, and enable convenient signal readout due to their unique physical and chemical properties...
January 9, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28054271/catalytic-reduction-of-2-nitroaniline-a-review
#16
Khalida Naseem, Robina Begum, Zahoor H Farooqi
2-nitroaniline (2-NA) is highly toxic and environmental contaminant. It is reduced to less toxic and environmental benign product o-phenylenediamine by using different reducing agents like sodium borohydride, potassium borohydride, or hydrazine hydrate in the presence of various catalytic systems. These catalytic systems have various advantages and drawbacks. Silica-supported gold nanoparticles are frequently reported catalyst for the reduction of 2-nitroaniline in aqueous medium. In this review article, different catalytic systems reported for reduction of o-nitroaniline under various reaction conditions have been discussed...
January 4, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28048528/we-h-206-01-photoacoustic-tomography-multiscale-imaging-from-organelles-to-patients-by-ultrasonically-beating-the-optical-diffusion-limit
#17
L Wang
: Lihong V. Wang: Photoacoustic tomography (PAT), combining non-ionizing optical and ultrasonic waves via the photoacoustic effect, provides in vivo multiscale functional, metabolic, and molecular imaging. Broad applications include imaging of the breast, brain, skin, esophagus, colon, vascular system, and lymphatic system in humans or animals. Light offers rich contrast but does not penetrate biological tissue in straight paths as x-rays do. Consequently, high-resolution pure optical imaging (e...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047869/we-h-206-02-recent-advances-in-multi-modality-molecular-imaging-of-small-animals
#18
B Tsui
: Lihong V. Wang: Photoacoustic tomography (PAT), combining non-ionizing optical and ultrasonic waves via the photoacoustic effect, provides in vivo multiscale functional, metabolic, and molecular imaging. Broad applications include imaging of the breast, brain, skin, esophagus, colon, vascular system, and lymphatic system in humans or animals. Light offers rich contrast but does not penetrate biological tissue in straight paths as x-rays do. Consequently, high-resolution pure optical imaging (e...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047205/we-h-206-03-promises-and-challenges-of-benchtop-x-ray-fluorescence-ct-xfct-for-quantitative-in-vivo-imaging
#19
S Cho
: Lihong V. Wang: Photoacoustic tomography (PAT), combining non-ionizing optical and ultrasonic waves via the photoacoustic effect, provides in vivo multiscale functional, metabolic, and molecular imaging. Broad applications include imaging of the breast, brain, skin, esophagus, colon, vascular system, and lymphatic system in humans or animals. Light offers rich contrast but does not penetrate biological tissue in straight paths as x-rays do. Consequently, high-resolution pure optical imaging (e...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046461/we-h-206-00-advances-in-preclinical-imaging
#20
Patrick La Riviere
: Lihong V. Wang: Photoacoustic tomography (PAT), combining non-ionizing optical and ultrasonic waves via the photoacoustic effect, provides in vivo multiscale functional, metabolic, and molecular imaging. Broad applications include imaging of the breast, brain, skin, esophagus, colon, vascular system, and lymphatic system in humans or animals. Light offers rich contrast but does not penetrate biological tissue in straight paths as x-rays do. Consequently, high-resolution pure optical imaging (e...
June 2016: Medical Physics
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