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Gold nanoparticles, review

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https://www.readbyqxmd.com/read/28613299/cellulose-gold-nanoparticle-hybrid-materials
#1
REVIEW
Jonas Van Rie, Wim Thielemans
Cellulose and gold nanoparticles have exciting characteristics and new combinations of both materials may lead to promising functional nanocomposites with unique properties. We have reviewed current research on cellulose-gold nanoparticle composite materials, and we present an overview of the preparation methods of cellulose-gold composite materials and discuss their applications. We start with the nanocomposite fabrication methods, covering in situ gold reduction, blending, and dip-coating methods to prepare gold-cellulose nanocomposite hybrids...
June 14, 2017: Nanoscale
https://www.readbyqxmd.com/read/28603606/synthesis-and-properties-of-magnetic-optical-core-shell-nanoparticles
#2
Elyahb Allie Kwizera, Elise Chaffin, Yongmei Wang, Xiaohua Huang
Due to their high integrity, facile surface chemistry, excellent stability, and dual properties from the core and shell materials, magnetic-plasmonic core-shell nanoparticles are of great interest across a number of science, engineering and biomedical disciplines. They are promising for applications in a broad range of areas including catalysis, energy conversion, biological separation, medical imaging, disease detection and treatment. The technological applications have driven the need for high quality nanoparticles with well controlled magnetic and optical properties...
March 19, 2017: RSC Advances
https://www.readbyqxmd.com/read/28579779/antibacterial-properties-and-toxicity-from-metallic-nanomaterials
#3
REVIEW
Gina V Vimbela, Sang M Ngo, Carolyn Fraze, Lei Yang, David A Stout
The era of antibiotic resistance is a cause of increasing concern as bacteria continue to develop adaptive countermeasures against current antibiotics at an alarming rate. In recent years, studies have reported nanoparticles as a promising alternative to antibacterial reagents because of their exhibited antibacterial activity in several biomedical applications, including drug and gene delivery, tissue engineering, and imaging. Moreover, nanomaterial research has led to reports of a possible relationship between the morphological characteristics of a nanomaterial and the magnitude of its delivered toxicity...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28559935/current-status-and-future-direction-of-nanomedicine-focus-on-advanced-biological-and-medical-applications
#4
REVIEW
Eun-Mi Kim, Hwan-Jeong Jeong
Nanotechnology is the engineering and manipulation of materials and devices with sizes in the nanometer range. Colloidal gold, iron oxide nanoparticles and quantum dot semiconductor nanocrystals are examples of nanoparticles, with sizes generally ranging from 1 to 20 nm. These nanotechnologies have been researched tremendously in the last decade and this has led to a new area of "nanomedicine" which is the application of nanotechnology to human health-care for diagnosis, monitoring, treatment, prediction and prevention of diseases...
June 2017: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28557630/the-exploitation-of-low-energy-electrons-in-cancer-treatment
#5
Mohammad Rezaee, Richard P Hill, David A Jaffray
Given the distinct characteristics of low-energy electrons (LEEs), particularly at energies less than 30 eV, they can be applied to a wide range of therapeutic modalities to improve cancer treatment. LEEs have been shown to efficiently produce complex molecular damage resulting in substantial cellular toxicities. Since LEEs are produced in copious amounts from high-energy radiation beam, including photons, protons and ions; the control of LEE distribution can potentially enhance the therapeutic radio of such beams...
May 30, 2017: Radiation Research
https://www.readbyqxmd.com/read/28528626/colloid-particle-formulations-for-antimicrobial-applications
#6
REVIEW
Ahmed F Halbus, Tommy S Horozov, Vesselin N Paunov
Colloidal particles are being extensively studied in various antimicrobial applications due to their small size to volume ratio and ability to exhibit a wide spectrum of antibacterial, antifungal, antialgal and antiviral action. The present review focuses on various nanoparticles (NPs) of inorganic, organic and hybrid materials, and discusses some of the methods for their preparation as well as mechanisms of their antimicrobial action. We consider the antimicrobial applications of metal oxide nanoparticles (ZnO, MgO, CuO, Cu2O, Al2O3, TiO2, CeO2 and Y2O3), metal nanoparticles (NPs), such as copper, silver and gold, metal hydroxide NPs such as Mg(OH)2 as well as hybrid NPs made from biodegradable materials, such as chitosan, lignin and dextran, loaded with other antimicrobial agents...
May 12, 2017: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/28507934/the-challenges-of-recombinant-endostatin-in-clinical-application-focus-on-the-different-expression-systems-and-molecular-bioengineering
#7
REVIEW
Abbas Mohajeri, Sarvin Sanaei, Farhad Kiafar, Amir Fattahi, Majid Khalili, Nosratollah Zarghami
Angiogenesis plays an essential role in rapid growing and metastasis of the tumors. Inhibition of angiogenesis is a putative strategy for cancer therapy. Endostatin (Es) is an attractive anti-angiogenesis protein with some clinical application challenges including; short half-life, instability in serum and requirement to high dosage. Therefore, production of recombinant endostatin (rEs) is necessary in large scale. The production of rEs is difficult because of its structural properties and is high-cost. Therefore, this review focused on the different expression systems that involved in rEs production including; mammalian, baculovirus, yeast, and Escherichia coli (E...
April 2017: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28503951/gold-nanoparticles-applications-from-artificial-enzyme-till-drug-delivery
#8
Kazem Golchin, Jafar Golchin, Shahrooz Ghaderi, Neda Alidadiani, Sajjad Eslamkhah, Masoud Eslamkhah, Soodabeh Davaran, Abolfazl Akbarzadeh
Today, nano-medicine promotes new therapeutics and diagnostics tools, including sensing of biomolecules as a biosensor, cancer chemotherapy and drug or gene delivery. Because of small size and biocompatibility of gold nanoparticles (GNPs), they become a good candidate for biological application. Also, thanks to their biological and chemical properties, they can mimic function of some enzymes including super oxide dismutase (SOD), esterase, etc. Also, biomaterials and bioengineering have grown so fast since the last decade for many therapeutic applications such as tissue regeneration...
May 14, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28489275/recent-drug-therapies-for-corneal-neovascularization
#9
REVIEW
Xinyao Liu, Shurong Wang, Xuanzhong Wang, Jiaming Liang, Yan Zhang
Corneal neovascularization (CNV) is a common pathological change in ocular surface diseases. It is not only the factor that affects vision but also the main cause for corneal graft failure. Based on the mechanism of CNV, many achievements have been developed to suppress the formation of CNV. There are certain novel drugs such as aflibercept, gold nanoparticles, and netrins which provide us with new clues to treat CNV. However, we still need to develop more effective therapeutic drugs. It is of great significance to develop new effective drugs to suppress the occurrence of CNV...
May 10, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28487853/promising-approaches-to-optimize-the-biological-properties-of-the-antimicrobial-peptide-esculentin-1a-1-21-nh2-amino-acids-substitution-and-conjugation-to-nanoparticles
#10
REVIEW
Bruno Casciaro, Floriana Cappiello, Mauro Cacciafesta, Maria Luisa Mangoni
Antimicrobial peptides (AMPs) represent an interesting class of molecules with expanding biological properties which make them a viable alternative for the development of future antibiotic drugs. However, for this purpose, some limitations must be overcome: (i) the poor biostability due to enzymatic degradation; (ii) the cytotoxicity at concentrations slightly higher than the therapeutic dosages; and (iii) the inefficient delivery to the target site at effective concentrations. Recently, a derivative of the frog skin AMP esculentin-1a, named esculentin-1a(1-21)NH2, [Esc(1-21): GIFSKLAGKKIKNLLISGLKG-NH2] has been found to have a potent activity against the Gram-negative bacterium Pseudomonas aeruginosa; a slightly weaker activity against Gram-positive bacteria and interesting immunomodulatory properties...
2017: Frontiers in Chemistry
https://www.readbyqxmd.com/read/28485601/hyaluronan-inorganic-nanohybrid-materials-for-biomedical-applications
#11
Zhixiang Cai, Hongbin Zhang, Yue Wei, Fengsong Cong
Nanomaterials, including gold, silver, and magnetic nanoparticles, carbon, and mesoporous materials, possess unique physiochemical and biological properties, thus offering promising applications in biomedicine, such as in drug delivery, biosensing, molecular imaging, and therapy. Recent advances in nanotechnology have improved the features and properties of nanomaterials. However, these nanomaterials are potentially cytotoxic and demonstrate a lack of cell-specific function. Thus, they have been functionalized with various polymers, especially polysaccharides, to reduce toxicity and improve biocompatibility and stability under physiological conditions...
May 16, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28460609/application-of-plasmonic-gold-nanoparticle-for-drug-delivery-system
#12
Jin-Ho Lee, Jeong-Woo Choi
Various kinds of colloidal nanoparticles (NPs) have been widely developed as a promising theranostic probe in biomedical fields. Particularly, colloidal gold nanoparticle (GNP) have been extensively utilized as theranostic probe for molecular imaging and drug delivery owing to their unique physiochemical properties with excellent biocompatibility. This review will outline the progress along this line and discuss about gold nanoparticle synthesis method for controlled geometry (spherical, rod and cage), surface functionalization (covalent and non-covalent) and associated in vitro/in vivo cytotoxicity as well as some of interesting diagnostic (imaging) and therapeutic (photo-thermal, drug delivery) applications...
April 27, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28451297/immunological-properties-of-gold-nanoparticles
#13
Lev A Dykman, Nikolai G Khlebtsov
In the past decade, gold nanoparticles have attracted strong interest from the nanobiotechnological community owing to the significant progress made in robust and easy-to-make synthesis technologies, in surface functionalization, and in promising biomedical applications. These include bioimaging, gene diagnostics, analytical sensing, photothermal treatment of tumors, and targeted delivery of various biomolecular and chemical cargos. For the last-named application, gold nanoparticles should be properly fabricated to deliver the cargo into the targeted cells through effective endocytosis...
March 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28447698/anisotropic-metal-nanoparticles-for-surface-enhanced-raman-scattering
#14
Javier Reguera, Judith Langer, Dorleta Jiménez de Aberasturi, Luis M Liz-Marzán
The optimization of the enhancement of Raman scattering by plasmonic effects is largely determined by the properties of the enhancing substrates. The main parameters behind this effect are related to the morphology of plasmonic nanoparticles and their relative distribution within the substrate. We focus this tutorial review on the effects of nanoparticle morphology, for the particular case of anisotropic metal nanoparticles. Anisotropy in silver and gold nanoparticles offers the possibility to tailor their plasmonic properties and intrinsic electromagnetic "hotspots"...
April 27, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28441776/gold-nanoparticles-for-modulating-neuronal-behavior
#15
REVIEW
Chiara Paviolo, Paul R Stoddart
Understanding the detailed functioning and pathophysiology of the brain and the nervous system continues to challenge the scientific community, particularly in terms of scaling up techniques for monitoring and interfacing with complex 3D networks. Nanotechnology has the potential to support this scaling up, where the eventual goal would be to address individual nerve cells within functional units of both the central and peripheral nervous system. Gold nanoparticles provide a variety of physical and chemical properties that have attracted attention as a light-activated nanoscale neuronal interface...
April 24, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28438268/fungal-biorecovery-of-gold-from-e-waste
#16
Saskia Bindschedler, Thi Quynh Trang Vu Bouquet, Daniel Job, Edith Joseph, Pilar Junier
Waste electric and electronic devices (e-waste) represent a source of valuable raw materials of great interest, and in the case of metals, e-waste might become a prized alternative source. Regarding gold, natural ores are difficult to mine due to their refractory nature and the richest ores have almost all been exploited. Additionally, some gold mining areas are present in geopolitically unstable regions. Finally, the gold mining industry produces toxic compounds, such as cyanides. As a result, the gold present in e-waste represents a nonnegligible resource (urban mining)...
2017: Advances in Applied Microbiology
https://www.readbyqxmd.com/read/28435252/polyphenol-nanoformulations-for-cancer-therapy-experimental-evidence-and-clinical-perspective
#17
REVIEW
Yasamin Davatgaran-Taghipour, Salar Masoomzadeh, Mohammad Hosein Farzaei, Roodabeh Bahramsoltani, Zahra Karimi-Soureh, Roja Rahimi, Mohammad Abdollahi
Cancer is defined as the abnormal cell growth that can cause life-threatening malignancies with high financial costs for patients as well as the health care system. Natural polyphenols have long been used for the prevention and treatment of several disorders due to their antioxidant, anti-inflammatory, cytotoxic, antineoplastic, and immunomodulatory effects discussed in the literature; thus, these phytochemicals are potentially able to act as chemopreventive and chemotherapeutic agents in different types of cancer...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28426435/surface-plasmon-resonance-in-gold-nanoparticles-a-review
#18
Vincenzo Amendola, Roberto Pilot, Marco Frasconi, Onofrio M Maragò, Maria Antonia Iatì
In the last two decades, plasmon resonance in gold nanoparticles (Au NPs) has been the subject of intense research efforts. Plasmon physics is intriguing and its precise modelling proved to be challenging. In fact, plasmons are highly responsive to a multitude of factors, either intrinsic to the Au NPs or from the environment, and recently the need emerged for the correction of standard electromagnetic approaches with quantum effects. Applications related to plasmon absorption and scattering in Au NPs are impressively numerous, ranging from sensing to photothermal effects to cell imaging...
May 24, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28425863/targeted-drug-delivery-based-on-gold-nanoparticle-derivatives
#19
Mazaher Gholipourmalekabadi, Mohammadmahdi Mobaraki, Maryam Ghaffari, Amir Zarebkohan, Vahid F Omrani, Aleksandra M Urbanska, Alexander Seifalian
Drug delivery systems are effective and attractive methods which allow therapeutic substances to be introduced into the body more effectively and safe by having tunable delivery rate and release target site. Gold nanoparticles (AuNPs) have a myriad of favorable physical, chemical, optical, thermal and biological properties that make them highly suitable candidates as non-toxic carriers for drug and gene delivery. The surface modifications of AuNPs profoundly improve their circulation, minimize aggregation rates, enhance attachment to therapeutic molecules and target agents due to their nano range size which further increases their ability to cross cell membranes and reduce overall cytotoxicity...
April 19, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28408882/targeted-nanotechnology-in-glioblastoma-multiforme
#20
REVIEW
Talita Glaser, Inbo Han, Liquan Wu, Xiang Zeng
Gliomas, and in particular glioblastoma multiforme, are aggressive brain tumors characterized by a poor prognosis and high rates of recurrence. Current treatment strategies are based on open surgery, chemotherapy (temozolomide) and radiotherapy. However, none of these treatments, alone or in combination, are considered effective in managing this devastating disease, resulting in a median survival time of less than 15 months. The efficiency of chemotherapy is mainly compromised by the blood-brain barrier (BBB) that selectively inhibits drugs from infiltrating into the tumor mass...
2017: Frontiers in Pharmacology
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