keyword
MENU ▼
Read by QxMD icon Read
search

Ginseng

keyword
https://www.readbyqxmd.com/read/28231544/ginsenoside-rg3-promotes-cytotoxicity-of-paclitaxel-through-inhibiting-nf-%C3%AE%C2%BAb-signaling-and-regulating-bax-bcl-2-expression-on-triple-negative-breast-cancer
#1
Zuguo Yuan, Hao Jiang, Xinhai Zhu, Xinge Liu, Jinhui Li
Taxane-based chemotherapy regimen is the most effective therapeutic strategy for triple-negative breast cancer (TNBC) which is an aggressive subtype of breast cancer with high rate of recurrence and distant metastasis. Ginsenoside Rg3 is isolated from Panax ginseng with anti-cancer activity against carcinomas. We aim to evaluate the chemosensitizing effects of Ginsenoside Rg3 on TNBC cells and xenograft and explore the underlying mechanism. Human triple-negative breast cancer lines MDA-MB-231, MDA-MB-453 and BT-549 were used...
February 20, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28216898/depolarizing-effects-of-daikenchuto-on-interstitial-cells-of-cajal-from-mouse-small-intestine
#2
Hyungwoo Kim, Hyun Jung Kim, Dongki Yang, Myeong Ho Jung, Byung Joo Kim
BACKGROUND: Daikenchuto (DKT; TJ-100, TU-100), a traditional herbal medicineis used in modern medicine to treat gastrointestinal (GI) functional disorders. Interstitial cells of Cajal (ICCs) are the pacemaker cells of the GI tract and play important roles in the regulation of GI motility. OBJECTIVE: The objective of this study was to investigate the effects of DKT on the pacemaker potentials (PPs) of cultured ICCs from murine small intestine. MATERIALS AND METHODS: Enzymatic digestions were used to dissociate ICCs from mouse small intestine tissues...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28187149/inhibition-of-influenza-a-virus-infection-by-ginsenosides
#3
Wei Dong, Amber Farooqui, Alberto J Leon, David J Kelvin
Influenza viruses cause mild to severe respiratory infections in humans. Due to efficient means of transmission, the viruses infect human population on a large scale. Apart from vaccines, antiviral drugs are used to control infection; neuraminidase inhibitors are thought to be the first choice of treatment, particularly for severe cases. Rapidly evolving and emerging influenza viruses with increased frequency of viral resistance to these drugs stress the need to explore novel antiviral compounds. In this study, we investigated antiviral activity of ginseng extract and ginsenosides, the ginseng-derived triterpene and saponin compounds, against 2009 pandemic H1N1 virus in vitro and in vivo...
2017: PloS One
https://www.readbyqxmd.com/read/28187027/investigating-the-effect-of-korean-red-ginseng-on-the-viability-of-random-pattern-skin-flaps-in-rats
#4
Hakan Tekin, Gönül Tekin, Gülay Bulut, Mustafa Fevzi Sargon, Dağhan Işik
OBJECTIVE: This experimental study investigated the efficacy of Korean Red Ginseng (KRG) extract in reducing the partial losses of random flaps. METHOD: Forty Wistar Albino rats were randomly distributed into 4 groups as (A) control group, (B) stress group, (C) oral KRG group, and (D) intraperitoneal KRG group. The modified McFarlane flap of 9 × 3 cm with a caudal pedicle was harvested from the back of the rats in all the groups. Korean Red Ginseng was administered to groups C and D at standard doses for 10 days...
February 10, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28168083/semiautomated-alignment-of-high-throughput-metabolite-profiles-with-chemometric-tools
#5
Ze-Ying Wu, Zhong-da Zeng, Zi-Dan Xiao, Daniel Kam-Wah Mok, Yi-Zeng Liang, Foo-Tim Chau, Hoi-Yan Chan
The rapid increase in the use of metabolite profiling/fingerprinting techniques to resolve complicated issues in metabolomics has stimulated demand for data processing techniques, such as alignment, to extract detailed information. In this study, a new and automated method was developed to correct the retention time shift of high-dimensional and high-throughput data sets. Information from the target chromatographic profiles was used to determine the standard profile as a reference for alignment. A novel, piecewise data partition strategy was applied for the determination of the target components in the standard profile as markers for alignment...
2017: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/28167883/enhancement-of-seed-dehiscence-by-seed-treatment-with-talaromyces-flavus-gg01-and-gg04-in-ginseng-panax-ginseng
#6
Min-Jeong Kim, Chang-Ki Shim, Yong-Ki Kim, Sung-Jun Hong, Jong-Ho Park, Eun-Jung Han, Seok-Cheol Kim
Seed dehiscence of ginseng (Panax ginseng C. A. Mayer) is affected by moisture, temperature, storage conditions and microbes. Several microbes were isolated from completely dehisced seed coat of ginseng cultivars, Chunpoong and Younpoong at Gumsan, Korea. We investigated the potential of five Talaromyces flavus isolates from the dehiscence of ginseng seed in four traditional stratification facilities. The isolates showed antagonistic activities against fungal plant pathogens, such as Cylindrocarpon destructans, Fusarium oxysporum, Rhizoctonia solani, Sclerotinia nivalis, Botrytis cinerea, and Phytophthora capsici...
February 2017: Plant Pathology Journal
https://www.readbyqxmd.com/read/28165424/changbai-mountain-ginseng-panax-ginseng-c-a-mey-extract-supplementation-improves-exercise-performance-and-energy-utilization-and-decreases-fatigue-associated-parameters-in-mice
#7
Guo-Dong Ma, Chun-Hui Chiu, Yi-Ju Hsu, Chien-Wen Hou, Yi-Ming Chen, Chi-Chang Huang
Changbai Mountain Ginseng (CMG, Panax ginseng C.A. Mey) is a traditional medicine commonly found in Northeast China and grows at elevations of 2000 m or higher in the Changbai Mountain Range. CMG, considered to be a "buried treasure medicine", is priced higher than other types of ginseng. However, few studies have demonstrated the effects of CMG supplementation on exercise performance, physical fatigue, and the biochemical profile. The major compound of CMG extract was characterized by electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS)...
February 5, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28156680/the-combination-therapy-with-methylphenidate-and-american-ginseng-in-cancer-related-fatigue
#8
Joshua Smith, Diane G Portman, Ritika Oberoi-Jassal, Sahana Rajasekhara, Mellar P Davis
: 215 Background: Fatigue is one of common symptoms among patients with cancer. However, little is known about the pathophysiology and effective pharmacologic intervention. Methylphenidate and American Ginseng were recognized for promising results and safe to use as a single therapy. Psycho-stimulants are commonly used and are effective in moderate to severe fatigue. The mechanism behind the evidence for methylphenidate is rebalancing dopamine neurotransmission which is altered in fatigue...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28156612/effects-of-high-dose-asian-ginseng-panax-ginseng-to-improve-cancer-related-fatigue-results-of-a-double-blind-placebo-controlled-randomized-controlled-trial
#9
Nizar M Tannir, Janet L Williams, Kenneth R Hess, Susan Frisbee-Hume, Helen L House, Frank V Fossella, Zita Dubauskas Lim, Gabriel Lopez, Akhila Sunkepally Reddy, Ahsan Azhar, Angelique Wong, Sunil M Patel, Ahmed Omar Kaseb, Wen-Jen Hwu, Zhanni Lu, Lorenzo Cohen, Eduardo Bruera
: 209 Background: Cancer related fatigue (CRF) is the most common and disabling symptom in cancer.Panax ginseng extract (PG) is frequently used as a nutraceutical treatment for fatigue. There are no well-powered placebo-controlled trials that used validated CRF outcome measures to investigate of PG effects in cancer patients. The primary objective of this trial was to evaluate the effects oral PG versus Placebo (PL) for CRF. METHODS: Patients with cancer fatigue ≥ 4/10 on Edmonton Symptom Assessment Scale (ESAS) were eligible...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28156441/strategy-of-using-herbal-extract-preparations-for-stage-iv-cancer-in-palliative-care-an-enhanced-and-maintenance-therapy
#10
Zhang Lingyan, Zhou Xiaoxia, Yin Weihua, Zhang Xiulian, Liu Hong, Duan Xiaopeng, Yu Cui, Luo Xiaolu, Zhong Qingfeng, Zhao Fen, Li Xianyong
: 89 Background: Palliative care is focused and seems as rationally anti-cancer way that have low systemic toxicity and acceptable effectiveness for stage IV cancer, especially herbal extracted medicines, which can regulate tumor microenviroment and body immune system. Our previous lab studies have indicated that TGF-beta, EGF, VEGF, IL-10 cytokines expression and mico-vessel density can be downgraded in tumor microenviroment by herbal extract preparation from Ginseng, Herba Agrimonia, Hairyvein and Arginine etc...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28154963/cytological-analysis-of-ginseng-carpel-development
#11
Jeniffer Silva, Yu-Jin Kim, Dexin Xiao, Johan Sukweenadhi, Tingting Hu, Woo-Saeng Kwon, Jianping Hu, Deok-Chun Yang, Dabing Zhang
Panax ginseng Meyer, commonly known as ginseng, is considered one of the most important herbs with pharmaceutical values due to the presence of ginsenosides and is cultivated for its highly valued root for medicinal purposes. Recently, it has been recognized that ginseng fruit contains high contents of triterpene such as ginsenoside Re as pharmaceutical compounds. However, it is unclear how carpel, the female reproductive tissue of flowers, is formed during the three-year-old growth before fruit is formed in ginseng plants...
February 2, 2017: Protoplasma
https://www.readbyqxmd.com/read/28150477/red-ginseng-as-an-ergogenic-aid-a-systematic-review-of-clinical-trials
#12
REVIEW
Nan Hee Lee, Hyun Chul Jung, Sukho Lee
Purpose: This systematic review was performed to summarize clinical trials assessing the effect of Red Ginseng (RG) supplementation on exercise performance and fatigue recovery. Methods: Two English databases (PUBMED, MEDLINE) and two Korean databases (KISS, RISS) were used as systematic searching engines. We included only articles written in the English and Korean languages. Clinical trials, which evaluated exercise performance and recovery variables with RG supplementation, were included in this review...
31, 2016: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/28143625/potential-benefits-of-phytochemicals-against-alzheimer-s-disease
#13
Emma L Wightman
Our current therapeutic drugs for Alzheimer's disease are predominantly derived from the alkaloid class of plant phytochemicals. These drugs, such as galantamine and rivastigmine, attenuate the decline in the cholinergic system but, as the alkaloids occupy the most dangerous end of the phytochemical spectrum (indeed they function as feeding deterrents and poisons to other organisms within the plant itself), they are often associated with unpleasant side effects. In addition, these cholinesterase inhibiting alkaloids target only one system in a disorder, which is typified by multifactorial deficits...
February 1, 2017: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/28128417/construction-and-transformation-of-expression-vector-containing-panax-japonicus-ss-gene
#14
L Zhang, T T Wang
Panax japonicus C.A. Meyer, a perennial herb belonging to the Araliaceae ginseng genus, is one of the seven rare and endangered Chinese medical herbs. By cloning the SS segment, the expression vectors pCXSN-PjSS and pCXSN-antiPjSS were constructed and introduced into Agrobactria LBA4404, which is used for engineering bacteria. Polymerase chain reaction (PCR) showed that the PjSS, antiPjSS, and Hyg were integrated in Nicotiana tabacum. Reverse transcription-PCR indicated that the PjSS was transcribed into mRNA in N...
January 23, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28126553/korean-red-ginseng-improves-testicular-ineffectiveness-in-aging-rats-by-modulating-spermatogenesis-related-molecules
#15
Spandana Rajendra Kopalli, Kyu-Min Cha, Ji-Hoon Ryu, Sang-Ho Lee, Min-Sik Jeong, Seock-Yeon Hwang, Young-Joo Lee, Hee-Won Song, Su-Nam Kim, Jin-Chul Kim, Si-Kwan Kim
Korean red ginseng (Panax ginseng Meyer) is known to rejuvenate testicular effectiveness and the sperm maturation process by regulating redox proteins in aged rats. This study was performed to investigate the effect of Korean red ginseng water extract (KRG-WE) on the expression level of spermatogenesis-related key biomolecules and sex hormone receptors as well as enzymes regulating oxidation, histone deacetylation, and growth-related activities in aged rat testis. KRG-WE (200mg/kg) mixed with a regular pellet diet was administered to 12-month-old rats for 6months (KRG-AC), whereas the young (YC, 2months) and aged (AC, 12months) controls received the vehicle only...
January 23, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28126050/rhodanobacter-rhizosphaerae-sp-nov-isolated-from-soil-of-ginseng-rhizosphere
#16
Geon-Yeong Cho, Jae-Chan Lee, Kyung-Sook Whang
A Gram-stain-negative, aerobic, non-motile, non-spore-forming, yellow and rod-shaped bacterium, designated strain CR164T, was isolated from the rhizosphere soil of a ginseng field at Geumsan in Korea. Strain CR164T grew between 15 and 37 °C (optimal growth at 28 °C), between pH 6.0 and 9.0 (optimal growth at pH 7.0) and at salinities of 0-1.0 % (w/v) NaCl, growing optimally in the absence of NaCl. Phylogenetic analyses based on 16S rRNA gene sequences indicated that strain CR164T belongs to the genus Rhodanobacter, showing the highest sequence similarity to Rhodanobacter caeni MJ01T (98...
January 26, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28123327/the-inhibitory-activity-of-ginsenoside-rp4-in-adenosine-diphosphate-induced-platelet-aggregation
#17
Young-Min Son, Da-Hye Jeong, Hwa-Jin Park, Man-Hee Rhee
BACKGROUND: Korean ginseng, Panax ginseng Meyer, has been used as a traditional oriental medicine to treat illness and promote health for several thousand years. Ginsenosides are the main constituents for the pharmacological effects of P. ginseng. Since several ginsenosides, including ginsenoside (G)-Rg3 and G-Rp1, have reported antiplatelet activity, here we investigate the ability of G-Rp4 to modulate adenosine diphosphate (ADP)-induced platelet aggregation. The ginsenoside Rp4, a similar chemical structure of G-Rp1, was prepared from G-Rg1 by chemical modification...
January 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28123326/discrimination-of-american-ginseng-and-asian-ginseng-using-electronic-nose-and-gas-chromatography-mass-spectrometry-coupled-with-chemometrics
#18
Shaoqing Cui, Jianfeng Wu, Jun Wang, Xinlei Wang
BACKGROUND: American ginseng (Panax quinquefolius L.) and Asian ginseng (Panax ginseng Meyer) products, such as slices, have a similar appearance, but they have significantly different prices, leading to widespread adulteration in the commercial market. Their aroma characteristics are attracting increasing attention and are supposed to be effective and nondestructive markers to determine adulteration. METHODS: The aroma characteristics of American and Asian ginseng were investigated using gas chromatography-mass spectrometry(GC-MS) and an electronic nose (E-nose)...
January 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28123325/metabolite-profiles-of-ginsenosides-rk1-and-rg5-in-zebrafish-using-ultraperformance-liquid-chromatography-quadrupole-time-of-flight-ms
#19
Wenwen Shen, Yingjie Wei, Daoquan Tang, Xiaobin Jia, Bin Chen
BACKGROUND: In the present study, metabolite profiles of ginsenosides Rk1 and Rg5 from red ginseng or red notoginseng in zebrafish were qualitatively analyzed with ultraperformance liquid chromatography/quadrupole-time-of-flight MS, and the possible metabolic were pathways proposed. METHODS: After exposing to zebrafish for 24 h, we determined the metabolites of ginsenosides Rk1 and Rg5. The chromatography was accomplished on UPLC BEH C18 column using a binary gradient elution of 0...
January 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28123324/antiaging-effects-of-the-mixture-of-panax-ginseng-and-crataegus-pinnatifida-in-human-dermal-fibroblasts-and-healthy-human-skin
#20
Eunson Hwang, Sang-Yong Park, Chang Shik Yin, Hee-Taek Kim, Yong Min Kim, Tae Hoo Yi
BACKGROUND: Human skin undergoes distinct changes throughout the aging process, based on both intrinsic and extrinsic factors. In a process called photoaging, UVB irradiation leads to upregulation of matrix metalloproteinase-1, which then causes collagen degradation and premature aging. Mixtures of medicinal plants have traditionally been used as drugs in oriental medicine. Based on the previously reported antioxidant properties of Panax ginseng Meyer and Crataegus pinnatifida, we hypothesized that the mixture of P...
January 2017: Journal of Ginseng Research
keyword
keyword
39395
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"