Myoung-Sook Shin, Ji Hoon Song, Pilju Choi, Jong Hun Lee, Song-Yi Kim, Kwang Soon Shin, Jungyeob Ham, Ki Sung Kang
Panax ginseng Meyer has been used for the treatment of immune diseases and for the strengthening the immune function. In this study, we evaluated the innate immune stimulating functions and action mechanisms of white ginseng (WG) and heat-processed ginseng (HPG) in RAW264.7 cells. According to LC-MS analysis results, WG contained typical ginsenosides, such as Rb1, Rc, Rb2, Rd, and Rg1, whereas HPG contained Rg3, Rk1, and Rg5 as well as typical ginsenosides. HPG, not WG enhanced NF-κB/AP-1 activity, cytokine production (IL-6 and TNF-α), and MHC class I and II expression in RAW264...
April 16, 2018: Journal of Agricultural and Food Chemistry