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https://www.readbyqxmd.com/read/28646759/free-standing-graphene-vanadium-oxide-composite-as-binder-free-electrode-for-asymmetrical-supercapacitor
#1
Lingjuan Deng, Yihong Gao, Zhanying Ma, Guang Fan
Preparation of free-standing electrode materials with three-dimensional network architecture has emerged as an effective strategy for acquiring advanced portable and wearable power sources. Herein, graphene/vanadium oxide (GR/V2O5) free-standing monolith composite has been prepared via a simple hydrothermal process. Flexible GR sheets acted as binder to connect the belt-like V2O5 for assembling three-dimensional network architecture. The obtained GR/V2O5 composite can be reshaped into GR/V2O5 flexible film which exhibits more compact structure by ultrasonication and vacuum filtration...
June 16, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28645370/xenopus-laevis-as-model-system-to-study-dna-damage-response-and-replication-fork-stability
#2
Vincenzo Sannino, Federica Pezzimenti, Stefania Bertora, Vincenzo Costanzo
Although many players of the DNA damage response and DNA repair have been identified in several systems their biochemical role is still poorly understood. The use of the Xenopus laevis egg extract cell-free system allowed biochemical dissection of DNA replication and cell cycle events in a complex biological context. The possibility of manipulating the protein content by using protein depletion procedures makes egg extract a powerful system to study proteins whose inactivation results in cellular lethality...
2017: Methods in Enzymology
https://www.readbyqxmd.com/read/28644716/the-effects-of-acute-carbohydrate-and-caffeine-feeding-strategies-on-cycling-efficiency
#3
Matthew Cole, James G Hopker, Jonathan D Wiles, Damian A Coleman
To assess the effect of carbohydrate and caffeine on gross efficiency (GE), 14 cyclists (V̇O2max 57.6 ± 6.3 ml.kg(-1.)min(-1)) completed 4 × 2-hour tests at a submaximal exercise intensity (60% Maximal Minute Power). Using a randomized, counter-balanced crossover design, participants consumed a standardised diet in the 3-days preceding each test and subsequently ingested either caffeine (CAF), carbohydrate (CHO), caffeine+carbohydrate (CAF+CHO) or water (W) during exercise whilst GE and plasma glucose were assessed at regular intervals (~30 mins)...
June 23, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28644506/reduced-graphene-oxide-coated-porous-carbon-sulfur-nanofiber-as-a-flexible-paper-electrode-for-lithium-sulfur-batteries
#4
R X Chu, J Lin, C Q Wu, J Zheng, Y L Chen, J Zhang, R H Han, Y Zhang, H Guo
Lithium-sulfur (Li-S) batteries have attracted great attention owing to their excellent electrochemical properties, such as the high discharge voltage of 2.3 V, specific capacity of 1675 mA h g(-1) and energy density of 2600 Wh kg(-1). The widely used slurry made electrodes of Li-S batteries are plagued by the serious shuttle effect and insulating nature of sulfur. Herein, a reduced graphene oxide coated porous carbon nanofiber flexible paper (rGO@S-PCNP) was fabricated and directly used as an additive-free cathode for Li-S batteries...
June 23, 2017: Nanoscale
https://www.readbyqxmd.com/read/28643264/genome-editing-of-c-elegans
#5
Takuma Sugi
Caenorhabditis elegans, a 1 mm long free-living nematode, is a traditional model animal for genetic investigations of various biological processes. Characteristic features that make C. elegans a powerful model of choice for eukaryotic genetic studies include its rapid life cycle, well-annotated genome, simple morphology, and transparency. Recently, genome editing technologies have been increasingly used in C. elegans, thereby facilitating their genetic analyses. Here, I introduce a protocol frequently used in C...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28642008/concurrent-once-daily-versus-twice-daily-chemoradiotherapy-in-patients-with-limited-stage-small-cell-lung-cancer-convert-an-open-label-phase-3-randomised-superiority-trial
#6
Corinne Faivre-Finn, Michael Snee, Linda Ashcroft, Wiebke Appel, Fabrice Barlesi, Adityanarayan Bhatnagar, Andrea Bezjak, Felipe Cardenal, Pierre Fournel, Susan Harden, Cecile Le Pechoux, Rhona McMenemin, Nazia Mohammed, Mary O'Brien, Jason Pantarotto, Veerle Surmont, Jan P Van Meerbeeck, Penella J Woll, Paul Lorigan, Fiona Blackhall
BACKGROUND: Concurrent chemoradiotherapy is the standard of care in limited-stage small-cell lung cancer, but the optimal radiotherapy schedule and dose remains controversial. The aim of this study was to establish a standard chemoradiotherapy treatment regimen in limited-stage small-cell lung cancer. METHODS: The CONVERT trial was an open-label, phase 3, randomised superiority trial. We enrolled adult patients (aged ≥18 years) who had cytologically or histologically confirmed limited-stage small-cell lung cancer, Eastern Cooperative Oncology Group performance status of 0-2, and adequate pulmonary function...
June 19, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28641269/a-model-based-tool-for-the-analysis-and-design-of-gene-regulatory-network
#7
Liliana Ironi, Ettore Lanzarone
Computational and mathematical models have significantly contributed to the rapid progress in the study of gene regulatory networks (GRN), but researchers still lack a reliable model-based framework for computer-aided analysis and design. Such tool should both reveal the relation between network structure and dynamics and find parameter values and/or constraints that enable the simulated dynamics to reproduce specific behaviors. This paper addresses these issues and proposes a computational framework that facilitates network analysis or design...
June 19, 2017: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/28640386/photoresponsive-smart-coloration-electrochromic-supercapacitor
#8
Tae Gwang Yun, Donghyuk Kim, Yong Ho Kim, Minkyu Park, Seungmin Hyun, Seung Min Han
Electrochromic devices have been widely adopted in energy saving applications by taking advantage of the electrode coloration, but it is critical to develop a new electrochromic device that can undergo smart coloration and can have a wide spectrum in transmittance in response to input light intensity while also functioning as a rechargeable energy storage system. In this study, a photoresponsive electrochromic supercapacitor based on cellulose-nanofiber/Ag-nanowire/reduced-graphene-oxide/WO3 -composite electrode that is capable of undergoing "smart" reversible coloration while simultaneously functioning as a reliable energy-storage device is developed...
June 22, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28639678/nitrogen-doped-graphene-anchored-with-mixed-growth-patterns-of-cupt-alloy-nanoparticles-as-a-highly-efficient-and-durable-electrocatalyst-for-the-oxygen-reduction-reaction-in-an-alkaline-medium
#9
Rajith Illathvalappil, Vishal M Dhavale, Siddheshwar N Bhange, Sreekumar Kurungot
A highly active and durable CuPt alloy catalyst with trigonal bipyramidal and truncated cube-type mixed morphologies, anchored on the nitrogen-doped graphene (NGr) surface (CuPt-TBTC/NGr), was prepared by a simple and fast method. The obtained CuPt alloy showed improved oxygen reduction reaction (ORR) activity, with a 30 mV positive shift in the half-wave potential value, as compared to the state-of-the-art Pt/C catalyst in a 0.1 M KOH solution. The CuPt alloy with the trigonal bipyramidal morphology possesses porous type inter-connected sides, which help to achieve improved mass transport of oxygen during the ORR...
June 22, 2017: Nanoscale
https://www.readbyqxmd.com/read/28639441/effect-of-periodized-high-intensity-interval-training-hiit-on-body-composition-and-attitudes-towards-hunger-in-active-men-and-women
#10
Todd A Astorino, Brendyn Heath, Jason Bandong, Gina M Ordille, Ramon Contreras, Matthew Montell, Matthew M Schubert
BACKGROUND: High intensity interval training (HIIT) increases maximal oxygen uptake similar to aerobic exercise. However, changes in body composition are equivocal in response to HIIT. AIM: We examined changes in body composition and dietary restraint in response to 20 sessions of HIIT varying in structure. METHODS: Thirty nine active men and women (age and VO2max = 22.5 ± 4.4 yr and 40.1 ± 5.6 mL/kg/min) were randomized to one of three periodized HIIT regimes performed on a cycle ergometer...
June 21, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28639347/high-energy-power-and-low-temperature-cathode-for-sodium-ion-batteries-in-situ-xrd-study-and-superior-full-cell-performance
#11
Jin-Zhi Guo, Peng-Fei Wang, Xing-Long Wu, Xiao-Hua Zhang, Qingyu Yan, Hong Chen, Jing-Ping Zhang, Yu-Guo Guo
Sodium-ion batteries (SIBs) are still confronted with several major challenges, including low energy and power densities, short-term cycle life, and poor low-temperature performance, which severely hinder their practical applications. Here, a high-voltage cathode composed of Na3 V2 (PO4 )2 O2 F nano-tetraprisms (NVPF-NTP) is proposed to enhance the energy density of SIBs. The prepared NVPF-NTP exhibits two high working plateaux at about 4.01 and 3.60 V versus the Na(+) /Na with a specific capacity of 127.8 mA h g(-1) ...
June 22, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28638780/materials-design-and-system-construction-for-conventional-and-new-concept-supercapacitors
#12
REVIEW
Zhong Wu, Lin Li, Jun-Min Yan, Xin-Bo Zhang
With the development of renewable energy and electrified transportation, electrochemical energy storage will be more urgent in the future. Supercapacitors have received extensive attention due to their high power density, fast charge and discharge rates, and long-term cycling stability. During past five years, supercapacitors have been boomed benefited from the development of nanostructured materials synthesis and the promoted innovation of devices construction. In this review, we have summarized the current state-of-the-art development on the fabrication of high-performance supercapacitors...
June 2017: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://www.readbyqxmd.com/read/28637278/functional-and-structural-analysis-of-at-specific-minor-groove-binders-that-disrupt-dna-protein-interactions-and-cause-disintegration-of-the-trypanosoma-brucei-kinetoplast
#13
Cinthia R Millan, Francisco J Acosta-Reyes, Laura Lagartera, Godwin U Ebiloma, Leandro Lemgruber, J Jonathan Nué Martínez, Núria Saperas, Christophe Dardonville, Harry P de Koning, J Lourdes Campos
Trypanosoma brucei, the causative agent of sleeping sickness (Human African Trypanosomiasis, HAT), contains a kinetoplast with the mitochondrial DNA (kDNA), comprising of >70% AT base pairs. This has prompted studies of drugs interacting with AT-rich DNA, such as the N-phenylbenzamide bis(2-aminoimidazoline) derivatives 1 [4-((4,5-dihydro-1H-imidazol-2-yl)amino)-N-(4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)benzamide dihydrochloride] and 2 [N-(3-chloro-4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)-4-((4,5-dihydro-1H-imidazol-2-yl)amino)benzamide] as potential drugs for HAT...
June 16, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28636819/superelastic-pseudocapacitors-from-freestanding-mno2-decorated-graphene-coated-carbon-nanotube-aerogels
#14
Yepin Zhao, Maxwell Patrick Li, Siyuan Liu, Mohammad F Islam
In recent years, the demand for emerging electronic devices has driven efforts to develop electrochemical capacitors with high power and energy densities that can preserve capacitance under and after recovery from mechanical deformation. We have developed superelastic pseudocapacitors using ≈ 1.5 mm thick graphene-coated single-walled carbon nanotube (SWCNT) aerogels decorated with manganese oxide (MnO2) as freestanding electrodes that retain high volumetric capacitance and electrochemical stability before, under, and after recovery from 50% compression...
June 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28635274/oxidation-state-dependent-binding-properties-of-the-active-site-in-a-mo-containing-formate-dehydrogenase
#15
William E Robinson, Arnau Bassegoda, Erwin Reisner, Judy Hirst
Molybdenum-containing formate dehydrogenase H from Escherichia coli (EcFDH-H) is a powerful model system for studies of the reversible reduction of CO2 to formate. However, the mechanism of FDH catalysis is currently debated, and whether the primary Mo coordination sphere remains saturated or one of the ligands dissociates to allow direct substrate binding during turnover is disputed. Here, we describe how oxidation state-dependent changes at the active site alter its inhibitor binding properties. Using protein film electrochemistry we show that formate oxidation by EcFDH-H is inhibited strongly and competitively by N3-, OCN-, SCN-, NO2- and NO3-, whereas CO2 reduction is inhibited only weakly and not competitively...
June 21, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28634346/generating-conditional-gene-knockouts-in-plasmodium-a-toolkit-to-produce-stable-dicre-recombinase-expressing-parasite-lines-using-crispr-cas9
#16
Ellen Knuepfer, Marta Napiorkowska, Christiaan van Ooij, Anthony A Holder
Successful establishment of CRISPR/Cas9 genome editing technology in Plasmodium spp. has provided a powerful tool to transform Plasmodium falciparum into a genetically more tractable organism. Conditional gene regulation approaches are required to study the function of gene products critical for growth and erythrocyte invasion of blood stage parasites. Here we employ CRISPR/Cas9 to facilitate use of the dimerisable Cre-recombinase (DiCre) that is frequently used to mediate the excision and loss of loxP-flanked DNA sequences in a rapamycin controlled manner...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28633918/traction-force-and-its-regulation-during-cytokinesis-in-dictyostelium-cells
#17
Md Golam Sarowar Jahan, Shigehiko Yumura
Cytokinesis is the final stage of cell division. Dictyostelium cells have multiple modes of cytokinesis, including cytokinesis A, B and C. Cytokinesis A is a conventional mode, which depends on myosin II in the contractile ring. Myosin II null cells divide depending on substratum-attachment (cytokinesis B) or in a multi-polar fashion independent of the cell cycle (cytokinesis C). We investigated the traction stress exerted by dividing cells in the three different modes using traction force microscopy. In all cases, the traction forces were directed inward from both poles...
June 12, 2017: European Journal of Cell Biology
https://www.readbyqxmd.com/read/28633815/ultrasound-assisted-selective-catalytic-transfer-hydrogenation-of-soybean-oil-using-5-pd-c-as-catalyst-under-ambient-conditions-in-water
#18
Sonam V Sancheti, Parag R Gogate
Catalytic transfer hydrogenation (CTH) is an alternative approach that does not require the use of potentially dangerous hydrogen gas. Pd/C is the most favoured catalyst for the selective hydrogenation of soybean oil yielding lower extent of formation of stearic acid and trans-isomer, which have adverse health effects. The present work deals with intensification of catalytic transfer hydrogenation of soybean oil in the presence of 5wt.% Pd/C using ultrasound under ambient reaction conditions. The effect of important operating parameters such as ultrasound power, temperature, type of hydrogen donor, catalyst loading and donor concentration on the progress of reaction has been investigated...
September 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28632498/can-early-ultrasonography-explain-the-lower-miscarriage-rates-in-twin-as-compared-to-singleton-pregnancies-following-assisted-reproduction
#19
Ana Póvoa, Alexandra Matias, Pedro Xavier, Isaac Blickstein
OBJECTIVE: To compare first trimester 2D conventional and 3D power Doppler angiography measures in twins and singletons following assisted reproduction. METHODS: We prospectively evaluated 50 singleton and 47 twin pregnancies that eventually ended in live births. Patients were recruited from a single assisted reproductive technology (ART) center with standard treatment protocols. Obstetric ultrasound was performed at 8-9 weeks +6 days. Intervillous flow, uteroplacental circulation and uterine artery pulsatility (PI) and resistance index (RI) using two-dimensional (2D) ultrasound examination were evaluated...
June 20, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28632144/optimal-pitching-axis-location-of-flapping-wings-for-efficient-hovering-flight
#20
Qi Wang, J Goosen, Fred Van Keulen
Flapping wings can pitch passively about their pitching axes due to their flexibility, inertia, and aerodynamic loads. A shift in the pitching axis location can dynamically alter the aerodynamic loads, which in turn changes the passive pitching motion and the flight efficiency. Therefore, it is of great interest to investigate the optimal pitching axis for flapping wings to maximize the power efficiency during hovering flight. In this study, flapping wings are modeled as rigid plates with non-uniform mass distribution...
June 20, 2017: Bioinspiration & Biomimetics
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