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https://www.readbyqxmd.com/read/29036731/rethinking-body-ownership-in-schizophrenia-experimental-and-meta-analytical-approaches-show-no-evidence-for-deficits
#1
Albulena Shaqiri, Maya Roinishvili, Mariia Kaliuzhna, Ophélie Favrod, Eka Chkonia, Michael H Herzog, Olaf Blanke, Roy Salomon
Schizophrenia is a severe psychiatric disorder, in which patients experience an abnormal sense of self. While deficits in sensorimotor self-representation (agency) are well documented in schizophrenia, less is known about other aspects of bodily self-representation (body ownership). Here, we tested a large cohort (N = 59) of chronic schizophrenia patients and matched controls (N = 30) on a well-established body illusion paradigm, the Full Body Illusion (FBI). In this paradigm, changes in body ownership are induced through prolonged multisensory stimulation, in which participants are stroked on their back while seeing the stroking on the back of a virtual body...
July 25, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29034066/novel-spect-technologies-and-approaches-in-cardiac-imaging
#2
Piotr Slomka, Guang-Uei Hung, Guido Germano, Daniel S Berman
Recent novel approaches in myocardial perfusion single photon emission CT (SPECT) have been facilitated by new dedicated high-efficiency hardware with solid-state detectors and optimized collimators. New protocols include very low-dose (1 mSv) stress-only, two-position imaging to mitigate attenuation artifacts, and simultaneous dual-isotope imaging. Attenuation correction can be performed by specialized low-dose systems or by previously obtained CT coronary calcium scans. Hybrid protocols using CT angiography have been proposed...
December 1, 2016: Cardiovasc Innov Appl
https://www.readbyqxmd.com/read/29033148/medial-approach-for-minimally-invasive-harvesting-of-a-deep-circumflex-iliac-artery-flap-for-reconstruction-of-the-jaw-using-virtual-surgical-planning-and-cad-cam-technology
#3
A Modabber, N Ayoub, A Bock, S C Möhlhenrich, B Lethaus, A Ghassemi, D A Mitchell, F Hölzle
Donor site morbidity is the most common limitation of the deep circumflex iliac artery (DCIA) flap, so the purpose of this paper is to describe a new, minimally-invasive, approach to its harvest using virtual surgical planning and CAD/CAM technology to reduce functional and aesthetic morbidity at the donor site. Virtual surgical planning was based on preoperative computed tomographic data. A newly-designed surgical guide made using CAD/CAM technology was used to transfer the virtual surgical plan to the site of operation...
October 12, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29032887/virtual-simulation-in-enhancing-procedural-training-for-fluoroscopy-guided-lumbar-puncture-a-pilot-study
#4
Saad Ali, Monther Qandeel, Rishi Ramakrishna, Carina W Yang
RATIONALE AND OBJECTIVES: Fluoroscopy-guided lumbar puncture (FGLP) is a basic procedural component of radiology residency and neuroradiology fellowship training. Performance of the procedure with limited experience is associated with increased patient discomfort as well as increased radiation dose, puncture attempts, and complication rate. Simulation in health care is a developing field that has potential for enhancing procedural training. We demonstrate the design and utility of a virtual reality simulator for performing FGLP...
October 9, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29032270/a-european-hla-isolate-and-its-implications-for-hsct-donor-procurement
#5
Tiina Linjama, Hans-Peter Eberhard, Juha Peräsaari, Carlheinz Müller, Matti Korhonen
BACKGROUND: Europeans have often been considered as one homogenous group in registry donor match predictions, but it is now evident that HLA haplotype frequencies vary across the European continent. Earlier studies have indicated that Finns in northeastern Europe have unique HLA characteristics, and the increasing availability of high resolution registry donor data is now making more detailed comparisons possible. STUDY DESIGN AND METHODS: In the first phase of the study, estimated HLA haplotype frequencies in stem cell donor registries of Finland and its neighbors Sweden and Russia were calculated using ZKRD's algorithm, and their frequencies were compared with each others' and with those of Germany...
October 12, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29031529/enhanced-surgical-outcomes-in-patients-with-skeletal-class-iii-facial-asymmetry-by-3-dimensional-surgical-simulation
#6
Ellen Wen-Ching Ko, Cheng-Hui Lin, Ying-An Chen, Yu-Ray Chen
PURPOSE: With the advance of image fusion techniques, the creation of 3-dimensional (3D) virtual head and 3D surgical simulations has provided previews of surgical procedures. The aim of this study was to investigate the surgical outcomes in patients receiving orthognathic surgery (OGS) with the guidance of 3D computer-assisted surgical simulation. PATIENTS AND METHODS: The study included 34 consecutive patients (15 men and 19 women; age, 18.1 to 33.0 yr) with skeletal Class III facial asymmetry who underwent bimaxillary OGS...
September 19, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29030753/successful-implementation-of-virtual-environment-for-radiotherapy-training-vert-in-medical-physics-education-the-university-of-sydney-s-initial-experience-and-recommendations
#7
Yobelli A Jimenez, Christian Rønn Hansen, Prabhjot Juneja, David I Thwaites
This report outlines the University of Sydney's initial experience with the Virtual Environment for Radiotherapy Training (VERT) system in the Master of Medical Physics program. VERT is a commercially available system, simulating linear accelerators, patient computed tomography (CT) sets, plans and treatment delivery. It was purpose built for radiation therapy (RT) education and offers learners the opportunity to gain knowledge and skills within an interactive, risk-free environment. The integration of VERT into the RT physics module of the Master of Medical Physics program was intended to enhance student knowledge and skills relevant to the curriculum's learning objectives, and to alleviate some of the burden associated with student access to clinical equipment...
October 13, 2017: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/29028510/comparison-of-virtual-monochromatic-series-iodine-overlay-maps-and-single-energy-ct-equivalent-images-in-head-and-neck-cancer-conspicuity
#8
Michael Kraft, Mohannad Ibrahim, Matthew Spector, Reza Forghani, Ashok Srinivasan
OBJECTIVE: To compare lesion conspicuity amongst DECT monochromatic series (40, 45, 50keV), and single-energy CT (SECT) equivalent images in head and neck squamous cell carcinomas (HNSCC). METHODS: Two readers compared DECT images to 70keV SECT equivalent series in 39 patients with HNSCC on lesion margin, enhancement, and overall conspicuity. RESULTS: The 45keV and 50keV images were significantly better (p-values ≤0.001) than the SECT equivalent in lesion enhancement, margins, and overall conspicuity for both readers...
September 29, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29027010/oxidized-regenerated-cellulose-induces-pleural-thickening-in-patients-with-pneumothorax-possible-involvement-of-the-mesothelial-mesenchymal-transition
#9
Hiroki Ebana, Takuo Hayashi, Keiko Mitani, Etsuko Kobayashi, Toshio Kumasaka, Teruaki Mizobuchi, Masatoshi Kurihara, Fumiyuki Takahashi, Kazuhisa Takahashi, Kuniaki Seyama
PURPOSE: The pleural covering technique, i.e., wrapping a part of or the entire surface of the lung with oxidized regenerative cellulose (ORC), reinforces visceral pleura through pleural thickening for patients with pneumothorax and cystic lung diseases. However, it remains undetermined how ORC induces pleural thickening. METHODS: A histopathological examination was performed for lung specimens from patients who had recurrent pneumothoraces after pleural covering and re-operation (n = 5)...
October 12, 2017: Surgery Today
https://www.readbyqxmd.com/read/29026407/congenital-hypothyroidism-insights-into-pathogenesis-and-treatment
#10
REVIEW
Christine E Cherella, Ari J Wassner
Congenital hypothyroidism occurs in approximately 1 in 2000 newborns and can have devastating neurodevelopmental consequences if not detected and treated promptly. While newborn screening has virtually eradicated intellectual disability due to severe congenital hypothyroidism in the developed world, more stringent screening strategies have resulted in increased detection of mild congenital hypothyroidism. Recent studies provide conflicting evidence about the potential neurodevelopmental risks posed by mild congenital hypothyroidism, highlighting the need for additional research to further define what risks these patients face and whether they are likely to benefit from treatment...
2017: International Journal of Pediatric Endocrinology
https://www.readbyqxmd.com/read/29025270/design-of-a-randomized-clinical-trial-of-a-colorectal-cancer-screening-decision-aid-to-promote-appropriate-screening-in-community-dwelling-older-adults
#11
Christine E Kistler, Carol Golin, Carolyn Morris, Alexandra F Dalton, Russell P Harris, Rowena Dolor, Renée M Ferrari, Noel T Brewer, Carmen L Lewis
BACKGROUND: Appropriate colorectal cancer screening in older adults should be aligned with the likelihood of net benefit. In general, patient decision aids improve knowledge and values clarity, but in older adults, they may also help patients identify their individual likelihood of benefit and foster individualized decision-making. We report on the design of a randomized clinical trial to understand the effects of a patient decision aid on appropriate colorectal cancer screening. This report includes a description of the baseline characteristics of participants...
August 1, 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/29025113/innovative-technology-using-virtual-reality-in-the-treatment-of-pain-does-it-reduce-pain-via-distraction-or-is-there-more-to-it
#12
Anita Gupta, Kevin Scott, Matthew Dukewich
Objective: Virtual reality (VR) is an exciting new technology with almost endless possible uses in medicine. One area it has shown promise is pain management. This selective review focused on studies that gave evidence to the distraction or nondistraction mechanisms by which VR leads to the treatment of pain. Methods: The review looked at articles from 2000 to July 29, 2016, focusing on studies concerning mechanisms by which virtual reality can augment pain relief...
August 31, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29024739/direct-antiviral-agents-daas-a-new-age-in-the-treatment-of-hepatitis-c-virus-infection
#13
REVIEW
Ulrich Spengler
Hepatitis C virus (HCV) is a global health problem, because infection frequently leads to chronic hepatitis C eventually progressing to liver cirrhosis and liver cancer. Improved insights into the HCV replication cycle and the role of HCV non-structural proteins has recently enabled to identify drugs directly acting on specific HCV target structures. Agents from three drug classes have been developed and approved by the health authorities. Combinations of two or more drugs from different classes achieve high (>90%) HCV clearance rates and are well tolerated...
October 9, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29020466/improving-post-stroke-cognitive-and-behavioral-abnormalities-by-using-virtual-reality-a-case-report-on-a-novel-use-of-nirvana
#14
Rosaria De Luca, Michele Torrisi, Adriana Piccolo, Giovanni Bonfiglio, Provvidenza Tomasello, Antonino Naro, Rocco Salvatore Calabrò
Cognitive impairment, as well as mood and anxiety disorders, occur frequently in patients following stroke. Aim of this study was to evaluate the effects of a combined rehabilitative treatment using conventional relaxation and respiratory techniques, in a specific rehabilitative virtual environment (by using Bts-Nirvana). A 58-year-old woman, affected by hemorrhagic stroke, underwent two different rehabilitation trainings, including either standard relaxation techniques alone in a common clinical setting or the same psychological approach in a semi-immersive virtual environment with an augmented sensorial (audio-video) and motor feedback (sensory motor-interaction)...
October 11, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/29020413/incidence-predictors-and-clinical-outcomes-of-coronary-obstruction-following-transcatheter-aortic-valve-replacement-for-degenerative-bioprosthetic-surgical-valves-insights-from-the-vivid-registry
#15
Henrique B Ribeiro, Josep Rodés-Cabau, Philipp Blanke, Jonathon Leipsic, Jong Kwan Park, Vinayak Bapat, Raj Makkar, Matheus Simonato, Marco Barbanti, Joachim Schofer, Sabine Bleiziffer, Azeem Latib, David Hildick-Smith, Patrizia Presbitero, Stephan Windecker, Massimo Napodano, Alfredo G Cerillo, Mohamed Abdel-Wahab, Didier Tchetche, Claudia Fiorina, Jan-Malte Sinning, Mauricio G Cohen, Mayra E Guerrero, Brian Whisenant, Fabian Nietlispach, José Honório Palma, Luis Nombela-Franco, Arend de Weger, Malek Kass, Fabio Sandoli de Brito, Pedro A Lemos, Ran Kornowski, John Webb, Danny Dvir
Aims: There are limited data on coronary obstruction following transcatheter valve-in-valve (ViV) implantation inside failed aortic bioprostheses. The objectives of this study were to determine the incidence, predictors, and clinical outcomes of coronary obstruction in transcatheter ViV procedures. Methods and results: A total of 1612 aortic procedures from the Valve-in-Valve International Data (VIVID) Registry were evaluated. Data were subject to centralized blinded corelab computed tomography (CT) analysis in a subset of patients...
August 14, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29019753/imaging-of-pediatric-growth-plate-disturbances
#16
Jie C Nguyen, B Keegan Markhardt, Arnold C Merrow, Jerry R Dwek
The growth plates, or physes, are visible on virtually all images obtained in skeletally immature children. The proper function of these growth plates depends on an intricate balance between chondrocyte proliferation, which requires nourishment from the epiphyseal vessels, and chondrocyte death, which requires the integrity of the metaphyseal vessels. Therefore, injury to the growth plate (ie, direct insult) or vascular compromise on either side of the growth plate (ie, indirect insult) can cause growth plate dysfunction...
October 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29018958/comparison-of-virtual-monoenergetic-and-polyenergetic-images-reconstructed-from-dual-layer-detector-ct-angiography-of-the-head-and-neck
#17
Victor Neuhaus, Nils Große Hokamp, Nuran Abdullayev, Volker Maus, Christoph Kabbasch, Anastasios Mpotsaris, David Maintz, Jan Borggrefe
OBJECTIVES: To compare the image quality of virtual monoenergetic images and polyenergetic images reconstructed from dual-layer detector CT angiography (DLCTA). METHODS: Thirty patients who underwent DLCTA of the head and neck were retrospectively identified and polyenergetic as well as virtual monoenergetic images (40 to 120 keV) were reconstructed. Signals (± SD) of the cervical and cerebral vessels as well as lateral pterygoid muscle and the air surrounding the head were measured to calculate the CNR and SNR...
October 10, 2017: European Radiology
https://www.readbyqxmd.com/read/29018956/remote-kinematic-training-for-patients-with-chronic-neck-pain-a-randomised-controlled-trial
#18
Hilla Sarig Bahat, Kate Croft, Courtney Carter, Anna Hoddinott, Elliot Sprecher, Julia Treleaven
PURPOSE: To evaluate short- and intermediate-term effects of kinematic training (KT) using virtual reality (VR) or laser in patients with chronic neck pain. METHODS: A randomised controlled trial with three arms (laser, VR, control) to post-intervention (N = 90), and two arms (laser or VR) continuing to 3 months follow-up. Home training intervention was provided during 4 weeks to VR and laser groups while control group waited. OUTCOME MEASURES: Primary outcome measures included neck disability index (NDI), global perceived effect (GPE), and cervical motion velocity (mean and peak)...
October 10, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29018926/optimisation-of-window-settings-for-traditional-and-noise-optimised-virtual-monoenergetic-imaging-in-dual-energy-computed-tomography-pulmonary-angiography
#19
Tommaso D'Angelo, Andreas M Bucher, Lukas Lenga, Christophe T Arendt, Julia L Peterke, Damiano Caruso, Silvio Mazziotti, Alfredo Blandino, Giorgio Ascenti, Ahmed E Othman, Simon S Martin, Doris Leithner, Thomas J Vogl, Julian L Wichmann
OBJECTIVES: To define optimal window settings for displaying virtual monoenergetic images (VMI) of dual-energy CT pulmonary angiography (DE-CTPA). METHODS: Forty-five patients who underwent clinically-indicated third-generation dual-source DE-CTPA were retrospectively evaluated. Standard linearly-blended (M_0.6), 70-keV traditional VMI (M70), and 40-keV noise-optimised VMI (M40+) reconstructions were analysed. For M70 and M40+ datasets, the subjectively best window setting (width and level, B-W/L) was independently determined by two observers and subsequently related with pulmonary artery attenuation to calculate separate optimised values (O-W/L) using linear regression...
October 10, 2017: European Radiology
https://www.readbyqxmd.com/read/29018791/a-novel-multiplayer-screen-based-simulation-experience-for-african-learners-improved-confidence-in-management-of-postpartum-hemorrhage
#20
Jeffrey M Taekman, Megan F Foureman, Fred Bulamba, Michael Steele, Emily Comstock, Andrew Kintu, Amy Mauritz, Adeyemi Olufolabi
INTRODUCTION: Postpartum hemorrhage (PPH) remains a global challenge, affecting thirteen million women each year. In addition, PPH is a leading cause of maternal mortality in Asia and Africa. In the U.S.A., care of critically ill patients is often practiced using mannequin-based simulation. Mannequin-based simulation presents challenges in global health, particularly in low- or middle-income countries. We developed a novel multiplayer screen-based simulation in a virtual world enabling the practice of team coordination with PPH...
2017: Frontiers in Public Health
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