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https://www.readbyqxmd.com/read/29116357/injectable-biomechanically-robust-biodegradable-and-osseointegrative-bone-cement-for-percutaneous-kyphoplasty-and-vertebroplasty
#1
Huiling Liu, Bin Liu, Chunxia Gao, Bin Meng, Huilin Yang, Haiyang Yu, Lei Yang
PURPOSE: Poly(methyl methacrylate) (PMMA) cement is widely used for percutaneous kyphoplasty and vertebroplasty (PKP and PVP) but possesses formidable shortcomings due to non-degradability. Here, a biodegradable replacement is developed. METHODS: Calcium phosphate cement (CPC) was redesigned by incorporating starch and BaSO4 (new cement named as CPB). The biomechanical, biocompatibility, osseointegrative and handling properties of CPB were systematically evaluated in vitro and in vivo by the models of osteoporotic sheep vertebra, rat subcutaneous implantation and rat femoral defect...
November 7, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29057346/corpectomy-and-expandable-cage-replacement-versus-third-generation-percutaneous-augmentation-system-in-case-of-vertebra-plana-rationale-and-recommendations
#2
Daniele Vanni, Andrea Pantalone, Vincenzo Magliani, Vincenzo Salini, Pedro Berjano
BACKGROUND: To evaluate the role of third generation percutaneous vertebral augmentation systems (Spine Jack(®)) as alternative to the corpectomies and expandable cages replacement (X-Core(®) Adjustable VBR System) in the treatment of vertebra plana (VP) as complication of the osteoporosis vertebral fracture (OVF). METHODS: Spine Jack(®) is a new device for mechanical kyphoplasty (MK). It is a titanium implant designed to restore the height of the vertebral body in OVF, primary or secondary bone tumors, or traumatic fractures...
September 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29057344/utilization-of-vertebroplasty-and-kyphoplasty-procedures-throughout-the-united-states-over-a-recent-decade-an-analysis-of-the-nationwide-inpatient-sample
#3
Joseph L Laratta, Jamal N Shillingford, Joseph M Lombardi, John D Mueller, Hemant Reddy, Comron Saifi, Charla R Fischer, Steven C Ludwig, Lawrence G Lenke, Ronald A Lehman
BACKGROUND: Given the increasing societal focus on health care utilization and value-based care, it is essential to understand the demographic and economic data surrounding percutaneous vertebral augmentation procedures performed in the United States. Double-blinded prospective randomized controlled trials have shown no benefit to the use of vertebroplasty over a sham procedure in the treatment of vertebral fractures. Contrastingly, kyphoplasty may be beneficial when appropriately indicated...
September 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29055740/percutaneous-balloon-kyphoplasty-for-treatment-of-very-severe-osteoporotic-vertebral-compression-fractures-a-case-controlled-study
#4
Jin Kyu Lee, Hae-Won Jeong, Il-Han Joo, Young-Il Ko, Chang-Nam Kang
BACKGROUND CONTEXT: There exists controversy regarding percutaneous balloon kyphoplasty (PBK) in patients with very severe osteoporotic vertebral compression fracture (vsOVCF). PURPOSE: The study was conducted to investigate the clinical and radiological outcomes of PBK for the treatment of vsOVCF compared with those of non-vsOVCF. STUDY DESIGN/SETTING: Retrospective, case controlled. PATIENT SAMPLE: 167 consecutive patients (210 vertebral bodies) who underwent PBK for OVCF between March 2010 and January 2015 were assessed...
October 18, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29030463/efficacy-and-safety-of-the-target-puncture-technique-for-treatment-of-osteoporotic-vertebral-compression-fractures-with-intravertebral-clefts
#5
Weibo Yu, De Liang, Xiaobing Jiang, Zhensong Yao, Ting Qiu, Linqiang Ye
OBJECTIVE: To compare the efficacy and safety of our target puncture technique with the traditional technique during percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCFs) with intravertebral clefts (IVCs). METHODS: 104 patients treated with PKP for single OVCFs with IVCs were retrospectively reviewed. All patients were divided into three groups: cleft filling by the traditional technique (Group A, n=18); interdigitated filling (Group B, n=50); and overfilling by the target technique (Group C, n=36)...
November 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28969223/evaluation-of-percutaneous-vertebroplasty-for-management-of-symptomatic-osteoporotic-compression-fracture
#6
Arnab Karmakar, Suchi Acharya, Dibyendu Biswas, Arkaprabha Sau
INTRODUCTION: Osteoporotic vertebral compression fractures are a leading cause of disability and associated morbidities among Indian population. Worldwide, approximately 20% of elderly population above 70 years and 16% of postmenopausal women are suffering from it. Vertebral compression fractures should be aggressively treated with minimally invasive techniques such as Percutaneous Vertebroplasty (PVP) or Percutaneous Kyphoplasty (PKP) to minimize pain and disability associated with it...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28952779/clinical-outcome-and-subsequent-sequelae-of-cement-extravasation-after-percutaneous-kyphoplasty-and-vertebroplasty-a-comparative-review
#7
Hassan Semaan, Tawfik Obri, Mohamad Bazerbashi, Daniel Paull, Xiaochen Liu, Marah Sarrouj, Hossein Elgafy
Background Injection of cement during vertebroplasty and kyphoplasty can leak into surrounding structures and could be symptomatic. Purpose To identify the sites and incidence of cement extravasation after kyphoplasty and vertebroplasty, and to evaluate their impacts on clinical outcomes. Material and Methods A retrospective review of 316 patients treated with kyphoplasty and vertebroplasty; 411 cases were included (223 kyphoplasty and 188 vertebroplasty). Cement extravasation was evaluated postoperatively by computed tomography (CT) scan of the spine...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28937459/percutaneous-kyphoplasty-for-the-treatment-of-osteoporotic-vertebral-fractures-with-intravertebral-fluid-or-air-a-comparative-study
#8
Junjie Niu, Dawei Song, Haifei Zhou, Qian Meng, Bin Meng, Huilin Yang
STUDY DESIGN: A retrospective comparative study. OBJECTIVE: To compare the characteristics of osteoporotic vertebral fractures (OVFs) with intravertebral fluid (IVF) and those with intravertebral air (IVA), and the efficacy of percutaneous balloon kyphoplasty (PKP) in treating OVFs with these 2 different intravertebral components. SUMMARY OF BACKGROUND DATA: Previous studies have focused on the efficacy of percutaneous vertebroplasty (PVP) and PKP in treating OVFs with intravertebral cleft...
October 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28856402/percutaneous-vertebroplasty-and-kyphoplasty-current-status-new-developments-and-old-controversies
#9
Dimitrios K Filippiadis, Stefano Marcia, Salvatore Masala, Frederic Deschamps, Alexis Kelekis
Vertebroplasty and kyphoplasty are minimally invasive techniques applied for the treatment of vertebral fractures. Since not all vertebral compression fractures are the same, a tailored-based approach is necessary for optimum efficacy and safety results. Nowadays, different cements and materials are proposed as alternatives to the original poly-methylmethacrylate aiming to overcome the limitations and the risks governing its use. Both techniques are governed by high efficacy and low complication rates; multilevel treatment in a single session has been shown to be feasible with no compromise of the technique's safety and efficacy...
August 30, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28829670/clinical-efficacy-analysis-of-percutaneous-kyphoplasty-combined-with-zoledronic-acid-in-the-treatment-and-prevention-of-osteoporotic-vertebral-compression-fractures
#10
Bin Liu, Fusheng Gan, Yu Ge, Haiyang Yu
OBJECTIVE: The aim of this study is to investigate the clinical efficacy of percutaneous kyphoplasty (PKP) combined with zoledronic acid (aclasta) in the treatment and prevention of osteoporotic vertebral compression fractures (OVCF). METHOD: A total of 104 patients with OVCF were treated with PKP from February 15, 2014 to January 17, 2016. All patients were randomly assigned to control and experimental groups, each group having 52 patients. All patients in the control group were treated with PKP...
August 22, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28816876/osteoporotic-thoracolumbar-fractures-how-are-they-different-classification-and-treatment-algorithm
#11
Shanmuganathan Rajasekaran, Rishi M Kanna, Klaus J Schnake, Alexander R Vaccaro, Gregory D Schroeder, Said Sadiqi, Cumhur Oner
Osteoporotic vertebral fractures constitute at least 50% of the osteoporotic fractures that happen worldwide. Occurrence of osteoporotic fractures make the elderly patient susceptible for further fractures and increases the morbidity due to kyphosis and pain; the mortality risk is also increased in these patients. Most fractures occur in the thoracic and thoracolumbar region and are often stable. Different descriptive and prognostic classification systems have been described, but none are universally accepted...
September 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28798871/application-of-pmma-bone-cement-composited-with-bone-mineralized-collagen-in-percutaneous-kyphoplasty
#12
Ming Bai, Heping Yin, Jian Zhao, Yang Li, Yongdong Yang, Yimin Wu
We investigated the feasibility of applying polymethylmethacrylate bone cement composited with biomimetic bone-mineralizsed collagen to percutaneous kyphoplasty (PKP). We performed PKP in 95 patients diagnosed with osteoporotic vertebral compression fracture. All patients had fractures of a single vertebral body, and they were divided randomly into control (group A, 47 patients) and experimental (group B, 48 patients) groups. Patients in group A were treated with acrylic cement, and those in group B were treated with acrylic cement composited with the bone graft material...
August 2017: Regenerative Biomaterials
https://www.readbyqxmd.com/read/28782368/analysis-of-risk-factors-causing-short-term-cement-leakages-and-long-term-complications-after-percutaneous-kyphoplasty-for-osteoporotic-vertebral-compression-fractures
#13
Chang Gao, Min Zong, Wen-Tao Wang, Lei Xu, Da Cao, Yue-Fen Zou
Background Percutaneous kyphoplasty (PKP) is a common treatment modality for painful osteoporotic vertebral compression fractures (OVCFs). Pre- and postoperative identification of risk factors for cement leakage and follow-up complications would therefore be helpful but has not been systematically investigated. Purpose To evaluate pre- and postoperative risk factors for the occurrence of short-term cement leakages and long-term complications after PKP for OVCFs. Material and Methods A total of 283 vertebrae with PKP in 239 patients were investigated...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28775319/circulating-tumour-cell-release-after-cement-augmentation-of-vertebral-metastases
#14
Malte Mohme, Sabine Riethdorf, Marc Dreimann, Stefan Werner, Cecile L Maire, Simon A Joosse, Frederic Bludau, Volkmar Mueller, Rui P L Neves, Nikolas H Stoecklein, Katrin Lamszus, Manfred Westphal, Klaus Pantel, Harriet Wikman, Sven O Eicker
Cement augmentation via percutaneous vertebroplasty or kyphoplasty for treatment of spinal metastasis is a well-established treatment option. We assessed whether elevated intrametastatic pressure during cement augmentation results in an increased dissemination of tumour cells into the vascular circulation. We prospectively collected blood from patients with osteolytic spinal column metastases and analysed the prevalence of circulating tumour cells (CTCs) at three time-points: preoperatively, 20 minutes after cement augmentation, and 3-5 days postoperatively...
August 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28736621/percutaneous-cement-augmentation-for-osteoporotic-vertebral-fractures
#15
REVIEW
Amer Sebaaly, Maroun Rizkallah, Falah Bachour, Firas Atallah, Pierre Emmanuel Moreau, Ghassan Maalouf
Thoracolumbar vertebral fracture incidents usually occur secondary to a high velocity trauma in young patients and to minor trauma or spontaneously in older people.Osteoporotic vertebral fractures are the most common osteoporotic fractures and affect one-fifth of the osteoporotic population.Percutaneous fixation by 'vertebroplasty' is a tempting alternative for open surgical management of these fractures.Despite discouraging initial results of early trials for vertebroplasty, cement augmentation proved its superiority for the treatment of symptomatic osteoporotic vertebral fracture when compared with optimal medical treatment...
June 2017: EFORT open reviews
https://www.readbyqxmd.com/read/28672969/comparative-study-on-the-biomechanics-between-improved-pvp-and-traditional-pkp-in-the-treatment-of-vertebral-peripheral-wall-damage-type-ovcf
#16
Tao Zhou, Hao Lin, Hongliang Wang, Xiaoqiang Chen, Fang He
We compared the biomechanics between improved percutaneous vertebroplasty (improved PVP) and traditional percutaneous kyphoplasty (PKP) in the treatment of vertebral peripheral wall damage-type osteoporotic vertebral compression fracture (OVCF). A total of 15 vertebral peripheral wall damage-type OVCF models of new calves (12-14 weeks) were treated with a decalcifying agent (Shandon TBD-1) with the vertebral compression fracture. The vertebral volume and anterior height before modeling, and the vertebral BMD before and after modeling were measured...
July 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28659547/balloon-kyphoplasty-under-three-dimensional-radiography-guidance
#17
Daisuke Umebayashi, Yu Yamamoto, Yasuhiro Nakajima, Masahito Hara
Percutaneous balloon kyphoplasty (PBKP) is generally performed under two-dimensional (2D) radiography guidance (lateral- and anteroposterior (A-P) views) using C-arm fluoroscopy. However, 2D images taken by single-plane or bi-plane fluoroscopy cannot provide information regarding axial views, particularly the Z axis. Lack of information regarding the Z axis prevents the creation of three-dimensional (3D) images. Currently, there has been a progress in interventional X-ray systems, and they are capable of providing 3D radiographic images using a rotational angiography mode which is used to create 3D angiographies...
September 15, 2017: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/28647158/a-systematic-review-of-unilateral-versus-bilateral-percutaneous-vertebroplasty-percutaneous-kyphoplasty-for-osteoporotic-vertebral-compression-fractures
#18
Shengping Yang, Changxian Chen, Hanlong Wang, Zhiqiang Wu, Lianqun Liu
OBJECTIVE: The aim of this study was to compare the unilateral and bilateral approaches in treating osteoporotic vertebral compression fractures. METHODS: Based on the principles and methods of the Cochrane systematic reviews, the records of the Cochrane Library, PubMed, Web of Science, Chinese Bio-medicine database, China Journal Full-text Database, VIP database, and Wanfang database were reviewed until October 2014. The randomized controlled trials on unilateral and bilateral approaches to percutaneous vertebroplasty (PVP)/percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures were included...
June 21, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28640112/cement-leakage-in-osteoporotic-vertebral-compression-fractures-with-cortical-defect-using-high-viscosity-bone-cement-during-unilateral-percutaneous-kyphoplasty-surgery
#19
Tie Liu, Zhe Li, Qingjun Su, Yong Hai
The purpose of this study was to investigate cement leakage (CL) in osteoporotic vertebral compression fractures (OVCFs) with cortical defect using high-viscosity bone cement during unilateral percutaneous kyphoplasty (PKP) surgery.This study included a series of 77 patients (23 males, 54 females) with single level osteoporotic vertebral body fracture (OVCF) who underwent unilateral PKP in our hospital. Preoperative x-ray, computed tomography (CT) scan, and 3-dimensional reconstructions were studied. During the PKP procedure, needle was carefully put to avoid too near to the cortical defect according to CT image...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28607331/a-retrospective-study-of-percutaneous-balloon-kyphoplasty-for-the-treatment-of-symptomatic-schmorl-s-nodes-5-year-results
#20
Sun Zhi-Yong, Zhao Huan, Ling Feng, Lv Nan-Ning, Zhu Xiao-Yu, Pi Bin, Lin Jun, Qian Zhong-Lai, Zhang Zhi-Ming, Yang Hui-Lin
BACKGROUND Despite literature supporting the efficiency of percutaneous balloon kyphoplasty (PKP) in treating osteoporotic and malignant vertebral compression fractures, few reports exist that document its use for treatment of symptomatic Schmorl's nodes (SNs) refractory to conservative treatment. Patients with symptomatic SNs could have pain in the vertebrae similar to an acute vertebral compression fracture. MRI is very helpful in diagnosing symptomatic SNs when x-ray and CT scan are unremarkable. In painful cases, the vertebrae bone marrow around the SNs is hyperintense on T2-weighted subsequence...
June 13, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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