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fever of undetermined origin

Motoharu Fukushi, Yukishige Ishibashi, Naoki Nago
Past clinical data are not currently used to calculate pretest probabilities, as they have not been put into a database in clinical settings. This observational study was designed to determine the initial reasons for utilizing home visits or visits to an outpatient urban clinic in Japan.All family medical clinic outpatients and patients visited by the clinic (total = 11,688) over 1460 days were enrolled.We used a Bayes theorem-based clinical decision support system to analyze codes for initial reason-for-encounter (examination and final diagnosis: pretest probability) and final diagnosis of patients with fever (conditional pretest probability)...
June 2017: Medicine (Baltimore)
Wuyang Ji, Miner Zhong, Yan You, K E Hu, Bin Wu
A 68-year-old woman was admitted to the Peking Union Medical College Hospital with a 6-week history of fever of undetermined origin. The computed tomography scan revealed a space-occupying lesion in the ascending colon and colonic endoscopy revealed a protrusive lesion in the initial segment of the ascending colon, occupying 3/5 of the lumen. Pathological examination of a biopsy specimen revealed malignant fibrous histiocytoma (MFH). The patient then underwent a laparotomy for right hemicolectomy and en bloc lymph node dissection...
June 2016: Molecular and Clinical Oncology
C-C Wang, L-Y Chen, K Liu, X-Q Liu, D-J Li
OBJECTIVE: This study was to determine whether Image-Guided Percutaneous Liver Biopsy (IGPLB) is a safe and accurate procedure in patients with Hepatosplenic Gamma-Delta T-Cell Lymphoma (HSTCL) characterized by hepatosplenomegaly, and provide a rapid and safe diagnostic approach in this rare group of patients with a generally poor outcome. PATIENTS AND METHODS: We report five patients who underwent IGPLB for an initial diagnosis of HSTCL, in whom diagnosis by bone marrow biopsy and blood smear had failed...
May 2016: European Review for Medical and Pharmacological Sciences
Na Zheng, Xian Min Xiao, Kui Ran Dong, Lian Chen, Yang Yang Ma, Kai Li
PURPOSE: Primary gastric tumors in infants and children are rare, and their diagnosis and treatment have not been standardized to date. The objective of the present retrospective study was to analyze the clinical characteristics of these tumors and explore possible improvements in their diagnosis and treatment. METHODS: The study included 15 children with a diagnosis of primary gastric tumor confirmed by pathology. Clinical manifestations, diagnostic methods and treatment were analyzed retrospectively, and postoperative conditions were assessed in follow-up evaluations...
May 2016: Journal of Cancer Research and Clinical Oncology
Darko Pucar, Kandace Klein, James Corley, Hadyn T Williams
Three months after deceased donor kidney transplant, a patient who presented with proteinuric renal dysfunction and fever of undetermined origin was found to have BK viruria by quantitative polymerase chain reaction analysis. An ¹¹¹In leukocyte scan showed increased renal transplant uptake consistent with nephritis and linear uptake in the knee. Venous duplex ultrasound revealed acute occlusive thrombosis in the superficial right lesser saphenous vein in the area of increased radiolabeled leukocyte uptake...
July 2015: Clinical Nuclear Medicine
M Taj, R N Qureshi, T Farzana, T S Shamsi, S S Ahmed
Patients with hematological disorders develop febrile neutropenia (FN); most of these events remain undetermined in origin. We performed a prospective study to determine the microbiological characteristics of infections and their response to the first-line antibiotic therapy in FN. The study was conducted at National Institute of Blood Disease and Bone Marrow Transplant. Two-hundred episodes of FN were assessed for the bacterial growth, antimicrobial susceptibility pattern and response to the first-line treatment of FN...
June 2015: Indian Journal of Hematology & Blood Transfusion
Gajanan Surewad, Ivona Lobo, Preeti Shanbag
A 12-year-old girl presented with prolonged fever with no obvious focus on either history or clinical examination. High-resolution computerized tomography of the chest revealed the 'tree-in-bud' sign in the right lung and necrotic mediastinal lymph nodes. Barium meal showed multiple ileal strictures. The child was treated with anti-tuberculous therapy for six months. At follow-up six months later, the child had gained weight and had no signs of intestinal obstruction. Tuberculosis is a common cause of fever of undetermined origin and should be investigated for especially in countries with a high prevalence...
October 2014: Journal of Clinical and Diagnostic Research: JCDR
Emma A Borkowski
A young dog was presented with lethargy and pyrexia of 2 days duration, not responding to empirical treatment. Thorough diagnostic investigation failed to determine the cause. A retropharyngeal abscess became apparent when it eroded into the carotid artery 2 days later. This case highlights the challenging nature of fever of undetermined origin (FUO) and the value of close monitoring for diagnosis and prompt intervention.
December 2014: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
F Mateo Vallejo, M R Dominguez Reinado, C Medina Achirica, M Diaz Oteros, J L Esteban Ramos, S Melero Brenes
INTRODUCTION: Retroperitoneal tumors are rare, mostly malignant. Locally aggressive, and more frequent in women in their 5th decade of life. Its symptoms are nonspecific, including abdominal pain and palpable mass. To diagnosis is helpful computed tomography and biopsy. It needs surgery for absolute healing. PRESENTATION OF CASE: 67 years old man was admitted with back pain and fever. Abdominal imaging tests showed a 15cm abdominal mass without clear organodependencia...
2014: International Journal of Surgery Case Reports
Prudence Tettey, Ebenezer Badoe, Theophilus Adiku, Eva Obodai, John Kofi Odoom
INTRODUCTION: Convulsions associated with fever and acute onset of unknown aetiology with case fatalities have become a long observed medical condition at the Child Health Department of the Korle-Bu Teaching Hospital. Children admitted to the department with seizures of undetermined origin and fever has been a source of diagnostic confusion. Studies from the Asia Pacific region suggest a link with non-polio enteroviruses. The aim of the study was to investigate the association between non-polio enterovirus and acute encephalopathy causing neurological morbidity in children...
2014: Pan African Medical Journal
Yayi He, Bingyin Shi, Xiaoyan Wu, Peng Hou, Yi Wang
We present a case of 75-year-old man with type 2 diabetes and emphysematous pyelonephritis (EPN). The patient presented with abdominal pain, fever of undetermined origin and progressive decrease in urine output. Computerized tomography scan revealed gas formation in the left renal parenchyma and capsule. A left nephrectomy was performed. He made a quick recovery. EPN should be taken into consideration in diabetic patients with symptoms of pyelonephritis who show a poor response to conventional treatment. Elective nephrectomy may be life saving in some patients...
January 1, 2012: Clinics and Practice
Yan-Jia Yang, Ya-Xin Li, Yan-Bin Liu, Mei Yang, Kai Liu
The current study presents a case of a 23-year-old male with CD30(+) nasal-type extranodal natural killer/T-cell lymphoma (NKTL), with unusual clinical features mimicking phlegmonous myositis. The patient initially presented with swelling and tenderness of the left lower limb, particularly around the left ankle. One month later, pharyngalgia and fever developed and the patient was treated with antibiotics for the phlegmonous inflammation, however, the symptoms were not relieved. A muscle biopsy was performed on the lesion and revealed diffuse infiltration of atypical lymphoid cells with irregular nuclei...
May 2014: Oncology Letters
José Roberto Lambertucci
No abstract text is available yet for this article.
January 2014: Revista da Sociedade Brasileira de Medicina Tropical
Mónica Santiago, José Hernán Martinez, Coromoto Palermo, Carlos Figueroa, Oberto Torres, Rafael Trinidad, Eva Gonzalez, Maria de Lourdes Miranda, Miosotis Garcia, Guillermo Villamarzo
We describe a 20-year-old man diagnosed with a myelodysplastic syndrome (MDS), admitted to our hospital due to pancytopenia and fever of undetermined origin after myelosuppression with chemotherapy. Disseminated aspergillosis (DIA) was suspected when he developed skin and lung involvement. A rapidly growing mass was detected on the left neck area, during hospitalization. A thyroid ultrasound reported a 3.7 × 2.5 × 2.9 cm oval heterogeneous structure, suggestive of an abscess versus a hematoma. Fine needle aspiration of the thyroid revealed invasion of aspergillosis...
2013: Case Reports in Endocrinology
Sumanth R Daram, Rajesh N Keswani
No abstract text is available yet for this article.
December 2013: Clinical Gastroenterology and Hepatology
Nahla A Azzam
Fever of undetermined origin always poses a challenging problem to the physician. Tuberculosis is an important health problem in developing countries. It is mostly seen in immune-compromised patients. And it is one of the common causes of fever of unknown origin. I am reporting a case of a splenic tuberculosis in 48 years old male who is not known of any immune deficiency state, he was presented with 3 weeks history of fever and found to have severe neutropenia and with negative work up for all hematological, rheumatological and malignant causes...
June 18, 2013: Annals of Clinical Microbiology and Antimicrobials
Alfonso Ciccone, Maria Grazia Celani, Raimondo Chiaramonte, Cristiana Rossi, Enrico Righetti
BACKGROUND: Explanations for the effectiveness of stroke units compared with general wards in reducing mortality, institutionalisation and dependence of people with stroke remain undetermined, and the discussion on the most effective stroke unit model is still up for debate. The intensity of non-invasive mechanical monitoring in many western countries is one of the main issues regarding the different models. This is because of its strong impact on the organisation of the stroke unit in terms of the number of personnel, their expertise, the infrastructure and costs...
May 31, 2013: Cochrane Database of Systematic Reviews
Jacqueline Depasse, Miguela A Caniza, Asmaa Quessar, Mohammad Khattab, Laila Hessissen, Raul Ribeiro, Siham Cherkaoui, Said Benchekroun, Katherine K Matthay
BACKGROUND: Overall survival from leukemia is less in low and middle-income countries than in high-income countries. Our purpose was to describe the incidence, clinical features, and mortality of febrile illness with or without documented infection in children and young adults treated for AML and ALL in two centers in Rabat and Casablanca during 2011. METHODS: This retrospective cohort study included patients <30 years of age who were newly diagnosed with AML and ALL in 2011 in Casablanca and Rabat...
June 2013: Pediatric Blood & Cancer
Ning Wu, Qiang Li, Chang-Xin Gu, Toqeer Ahmed, Xiao-Peng Yao
BACKGROUND: Paraneoplastic syndromes (PNSs) are common complications of lung cancer and often develop preceding the diagnosis of primary malignancy. Rheumatologic PNSs mimicking Adult-Onset Still' s Disease (AOSD) is a rare condition with only a limited number of cases reported in the literature, none of which was associated with lung cancer. It is often difficult to differentiate AOSD-like paraneoplasia from coincidental AOSD based on the clinical manifestations. CASE PRESENTATION: Here we present a 56-year-old man with advanced lung adenocarcinoma who developed a remittent fever together with pharyngodynia and joint pain after first cycle of chemotherapy with paclitaxel plus carboplatin...
2011: BMC Cancer
Mazin Merdad, Mark Crawford, Karen Gordon, Blake Papsin
PURPOSE: In an effort to decrease postoperative opioid requirements, intraoperative bilateral superficial cervical plexus block (BSCPB) was recently adopted for all our children undergoing general anesthesia for bilateral simultaneous cochlear implantation (BSiCI). Several cases of early postoperative fever were noted after the adoption of BSCPB. Our aim was to determine if an association exists between BSCPB and early postoperative fever in children undergoing BSiCI. As a secondary outcome, we studied the efficacy of BSCPB in altering postoperative analgesic requirements...
January 2012: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
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