Tomomi Tanigaki, Yoshifumi Kimizuka, Yohei Maki, Chikako Sato, Shinya Yoshimatsu, Hiraku Ogata, Sakika Nomura, Masashi Nishimura, Yusuke Serizawa, Koki Ito, Shunya Igarashi, Yuhei Kurata, Tomohiro Ohno, Jun Miyata, Yuji Fujikura, Kimiya Sato, Sho Ogata, Akihiko Kawana
Anti-interferon (IFN)-γ autoantibody-positive syndrome is one of the acquired non-HIV cellular immunodeficiencies, caused by abnormalities in the IFN-γ/interleukin (IL)-12 pathways. It is often diagnosed alongside the onset of disseminated mycobacterium infection, and requires continuous antimycobacterial chemotherapy; however, the detailed pathological mechanisms underlying this syndrome, including its prognosis, are not known. To the best of our knowledge, this is the first reported case of intravascular large B-cell lymphoma complicated by anti-IFN-γ autoantibody syndrome, presented in an 82-year-old woman...
August 2, 2022: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy