Marco Lorenzo Bonù, Luca Nicosia, Ana Turkaj, Edoardo Pastorello, Paola Vitali, Francesco Frassine, Cristian Toraci, Luigi Spiazzi, Marco Lechiara, Barbara Frittoli, Luigi Grazioli, Paolo Ghirardelli, Gianluca Costantino, Fernando Barbera, Paolo Borghetti, Luca Triggiani, Nazario Portolani, Michela Buglione, Francesco Dionisi, Irene Giacomelli, Andrea Lancia, Stefano Maria Magrini, Davide Tomasini
BACKGROUND: Stereotactic radiotherapy (SRT) and Proton therapy (PT) are both options in the management of liver lesions. Limited clinical-dosimetric comparison are available. Moreover, dose-constraint routinely used in liver PT and SRT considers only the liver spared, while optimization strategies to limit the liver damaged are poorly reported. METHODS: Primary endpoint was to assess and compare liver sparing of four contemporary RT techniques. Secondary endpoints were freedom from local recurrence (FFLR), overall survival (OS), acute and late toxicity...
February 12, 2024: La Radiologia Medica