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https://www.readbyqxmd.com/read/27913260/patients-preference-of-the-timed-up-and-go-tug-test-or-patient-reported-outcome-measures-proms-before-and-after-surgery-for-lumbar-degenerative-disc-disease
#1
Holger Joswig, Martin N Stienen, Nicolas R Smoll, Marco V Corniola, Ivan Chau, Karl Schaller, Gerhard Hildebrandt, Oliver P Gautschi
BACKGROUND: The Timed Up and Go (TUG) test, as a measure of objective functional impairment in lumbar degenerative disc disease (DDD), complements patient-reported outcome measures (PROMs) of subjective functional impairment. METHODS: Prospective two-center study on consecutive patients scheduled for surgical treatment for lumbar DDD who underwent an objective (TUG test) and subjective (PROMs) functional assessment before, as well as one and three days after surgery...
November 29, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27908173/pacemaker-and-icd-oversensing-induced-by-movements-near-the-mri-scanner-bore
#2
E Mattei, F Censi, G Calcagnini, R Falsaperla, E Genovese, A Napolitano, V Cannatà
PURPOSE: The effect of the movement near the MRI scanner bore for people with a pacemaker (PM) or an implantable cardioverter defibrillator (ICD) is experimentally evaluated and discussed. METHODS: The authors performed in vitro measurements on a saline-filled human-shaped phantom (male, 170 cm height), equipped first with an MR-conditional PM (bicameral configuration, DDD programming), then with an MR-conditional ICD (biventricular configuration, detection algorithms enable but shock delivery disable)...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27903362/-levels-of-dichlorodiphenyltrichloroethane-internal-exposure-levels-in-pregnant-women-of-xiamen-and-influencing-factors
#3
X S Yu, J He, J H Chen, Z B Lai, Y H Su, M M Shi, Z X Huang, Q J Cheng, X Y Ke, B H Zhao
Objective: To investigate the level of and factors influencing internal exposure to dichlorodiphenyltrichloroethane (DDT) in pregnant women. Methods: In all, 1 064 pregnant women were recruited in a hospital of Xiamen. Participants were asked to complete a questionnaire to obtain data on sociodemographic characteristics and lifestyle. Peripheral venous blood and cord blood samples were collected. Of the 1 064 pregnant women, 600 were enrolled in this study after completing the questionnaire and providing peripheral venous blood and cord blood...
November 6, 2016: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/27899175/bioaccumulation-of-sediment-bound-dichlorodiphenyltrichloroethane-and-heavy-metals-in-benthic-polychaete-nereis-succinea-from-a-typical-mariculture-zone-in-south-china
#4
Huizhen Li, Fei Wang, Jing You
: Bioaccumulation potential and associated ecological risk of sediment-bound DDT and its metabolites (DDXs) and heavy metals in Hailing Bay, a typical mariculture zone along the southern coast of China, were evaluated. The estuarine sediments were co-polluted by DDXs (120-4882ng/g dry wt.) and heavy metals (292-409mg/kg dry wt.). Both DDXs and metals in sediment were bioavailable to Nereis succinea, although the biota-sediment accumulation factors were less than 1 except for DDE. Significant transformation of DDT in organism was observed and DDE was the main metabolite...
November 26, 2016: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/27894283/small-lung-lesions-invisible-under-fluoroscopy-are-located-accurately-by-three-dimensional-localization-technique-on-chest-wall-surface-and-performed-bronchoscopy-procedures-to-increase-diagnostic-yields
#5
Chaosheng Deng, Xiaoming Cao, Dawen Wu, Haibo Ding, Ruixiong You, Qunlin Chen, Linying Chen, Xin Zhang, Qiaoxian Zhang, Yongquan Wu
BACKGROUND: Nowadays, small peripheral pulmonary lesions (PPLs) are frequently detected and the prognosis of lung cancer depends on the early diagnosis. Because of the high fee and requiring specialized training, many advanced techniques are not available in many developing countries and rural districts. METHODS: Three sets of opaque soft copper wires visible under the fluoroscopy (Flu) in the Flu-flexible bronchoscopy (FB) group (n = 24), which determined the three planes of the lesion, were respectively placed firmly on the surface of the chest wall with adhesive tape on the chest wall...
November 29, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27888772/adrenocortical-sensitivity-moderated-by-ongoing-stress-predicts-drinking-intensity-in-alcohol-dependent-men
#6
Bryon Adinoff, David Leonard, Julianne Price, Martin A Javors, Robrina Walker, E Sherwood Brown, Hong Xiao, Uma Rao
Allostatic load from both environmental stressors and persistent glucocorticoid secretion has been associated with disease severity in alcohol dependence. Heightened relapse risk and/or drinking severity, in particular, may be a reaction to alcohol- and withdrawal-induced changes in physiological stress response systems coupled with ongoing life stress, although their shared contributions upon drinking severity have not been assessed. To investigate the combined contribution of hypothalamic-pituitary-adrenal (HPA) reactivity and environmental stressors (e...
November 5, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27888086/effects-of-smoking-on-subjective-and-objective-measures-of-pain-intensity-functional-impairment-and-health-related-quality-of-life-in-lumbar-degenerative-disc-disease
#7
Holger Joswig, Martin N Stienen, Nicolas R Smoll, Marco V Corniola, Ivan Chau, Karl Schaller, Gerhard Hildebrandt, Oliver P Gautschi
BACKGROUND: Numerous studies assessed the effects of smoking on lumbar degenerative disc disease (DDD); they focused on patient-reported outcomes measures (PROMs) and yielded conflicting results. METHODS: In this two-center study on consecutive patients receiving surgical treatment for lumbar DDD, subjective functional impairment (SFI) in terms of PROMs including visual analog scale back and leg pain, Roland-Morris, Oswestry Disability Index, Euro-Qol, Short Form-12 physical component summary was determined at baseline, three days, six weeks, six months and one year postoperatively...
November 22, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27887595/antimicrobial-stewardship-of-chinese-ministry-of-health-reduces-multidrug-resistant-organism-isolates-in-critically-ill-patients-a-pre-post-study-from-a-single-center
#8
Xudong Ma, Jianfeng Xie, Yi Yang, Fengmei Guo, Zhiwei Gao, Hua Shao, Yingzi Huang, Congshan Yang, Haibo Qiu
BACKGROUND: China's Ministry of Health (MOH) has established a policy about the antimicrobial stewardship. To date, the effects of this policy on multidrug-resistant organism (MDRO) in critically ill patients are unknown. METHODS: A pre-post study was conducted on intensive care unit (ICU) patients from June 2010 to May 2011 and from June 2012 to May 2013. Bacterial cultures were conducted at ICU admission and discharge. In June 2011, our hospital started to administer the antimicrobial stewardship program of Chinese MOH...
November 25, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27878657/c3-glomerulopathy-and-current-dilemmas
#9
Naoko Ito, Ryuji Ohashi, Michio Nagata
C3 glomerulopathy (C3G) is a recently identified disease entity caused by dysregulation of the alternative complement pathway, and dense deposit disease (DDD) and C3 glomerulonephritis (C3GN) are its components. Because laboratory detection of complement dysregulation is still uncommon in practice, "dominant C3 deposition by two orders greater than that of immunoglobulins in the glomeruli by immunofluorescence", as stated in the consensus report, defines C3G. However, this morphological definition possibly includes the cases with glomerular diseases of different mechanisms such as post-infectious glomerulonephritis...
November 23, 2016: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/27878559/impact-of-drug-manipulation-on-seizure-freedom-in-adults-with-uncontrolled-epilepsy-a-prospective-controlled-study-in-rural-china
#10
Xiaoting Hao, Ziyi Chen, Bo Yan, Patrick Kwan, Dong Zhou
INTRODUCTION: It has been suggested that uncontrolled epilepsy might not necessarily equate to drug resistance when antiepileptic drugs (AEDs) are used at relatively low doses, a practice frequently observed in rural areas of China. OBJECTIVE: To assess the clinical benefits of further drug manipulation in this situation, we prospectively followed up the outcomes of patients with uncontrolled epilepsy while taking relatively low doses of AEDs. METHODS: The study included patients aged 16 years and older with uncontrolled epilepsy and who were receiving at least one AED at a dosage below 50% of the World Health Organization (WHO) defined daily dose (DDD) (50% DDD) (Group 1)...
November 22, 2016: CNS Drugs
https://www.readbyqxmd.com/read/27876223/monitoring-of-organochlorine-pesticides-in-blood-of-women-with-uterine-cervix-cancer
#11
Ángel G Polanco Rodríguez, M Inmaculada Riba López, T Ángel DelValls Casillas, J Alfredo Araujo León, Olfa Mahjoub, Anjan Kumar Prusty
In Yucatan, Mexico, chronic exposure of Mayan population to pesticides is expected as about 30 per cent are drinking polluted water. Residues of organochlorine pesticides (OCP) were monitored in 18 municipalities of Yucatan with high mortality rates due to uterine cervix cancer. 70 blood samples collected from Mayan women living in livestock, agricultural and metropolitan area were analyzed for OCP. Solid Phase Extraction was performed on C18 cartridges and analyzed by Gas Chromatography with Electron Capture Detector...
November 18, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27873048/the-usefulness-of-radiological-grading-scales-to-predict-pain-intensity-functional-impairment-and-health-related-quality-of-life-after-surgery-for-lumbar-degenerative-disc-disease
#12
Oliver P Gautschi, Martin N Stienen, Holger Joswig, Nicolas R Smoll, Karl Schaller, Marco V Corniola
PURPOSE: The goal of this study is to determine the relationship of radiological grading scales of lumbar degenerative disc disease (DDD) with postoperative pain intensity, functional impairment, and health-related quality of life (HRQoL). METHODS: Response to surgical treatment at 6 weeks (W6) on the visual analogue scale (VAS) for back and leg pain, Oswestry-Disability (ODI) and Roland-Morris Disability Index (RMDI), Timed Up and Go (TUG) test, EuroQol (EQ) 5D, and Short-Form Health-Survey (SF-12) physical component summary (PCS) was compared between patients with different Modic (MOD) and Pfirrmann (PFI) grades...
November 21, 2016: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27866855/possible-emissions-of-pops-in-plain-and-hilly-areas-of-nepal-implications-for-source-apportionment-and-health-risk-assessment
#13
Ishwar Chandra Yadav, Ningombam Linthoingambi Devi, Jun Li, Gan Zhang, Knut Breivik
Ambient air is a core media chosen for monitoring under the Stockholm Convention on POPs. While extensive monitoring of POPs in ambient air has been carried out in some parts of the globe, there are still regions with very limited information available, such as some developing countries as Nepal. This study therefore aims to target the occurrence of selected POPs in Nepal in suspected source areas/more densely populated regions. Four potential source regions in Nepal were furthermore targeted as it was hypothesized that urban areas at lower altitudes (Birgunj and Biratnagar located at approximately 86 and 80 m...
November 17, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27865491/prevalence-and-risk-factors-for-extended-spectrum-beta-lactamase-or-ampc-producing-escherichia-coli-in-organic-dairy-herds-in-the-netherlands
#14
I M G A Santman-Berends, M A Gonggrijp, J J Hage, A E Heuvelink, A Velthuis, T J G M Lam, G van Schaik
Extended-spectrum β-lactamase and AmpC-producing Escherichia coli (ESBL/AmpC) are an emerging problem and are hypothesized to be associated with antimicrobial use (AMU), and more specifically with the use of third- and fourth-generation cephalosporins. Whether ESBL/AmpC also occur in organic dairy herds, which have restricted AMU, is not known. Additionally, it is unknown whether, in addition to restricted AMU, other factors in organic herd management are associated with ESBL/AmpC herd status. The aim of this study was to estimate the prevalence of ESBL/AmpC in organic dairy herds in the Netherlands...
November 16, 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/27863522/cardiometabolic-health-prescribed-antipsychotics-and-health-related-quality-of-life-in-people-with-schizophrenia-spectrum-disorders-a-cross-sectional-study
#15
Daniel Bressington, Jolene Mui, Mei Ling Tse, Richard Gray, Eric F C Cheung, Wai Tong Chien
BACKGROUND: People with schizophrenia-spectrum disorders (SSD) often have high levels of obesity and poor cardiometabolic health. Certain types of antipsychotics have been shown to contribute towards weight gain and there is some equivocal evidence that obesity is related to poor health-related quality of life (HRQoL) in people with SSD. It is also still uncertain if antipsychotic polypharmacy/higher doses of antipsychotics are linked with HRQoL and/or increased risk of obesity/Cardiovascular Disease (CVD)...
November 18, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27862414/epidemiology-and-cost-implications-of-candidemia-a-6-year-analysis-from-a-developing-country
#16
Aysegul Ulu Kilic, Emine Alp, Fatma Cevahir, Zeynep Ture, Nuran Yozgat
Surveillance of candidemia is essential to monitor trends in species distribution and change in the incidence and antifungal resistance. In this study, we aimed to investigate prevalence, resistance rates, antifungal utilization and costs. A 6-year retrospective analysis of the data belonging to patients with candidemia hospitalized between 2010 and 2016 was performed. The annual usage of fluconazole and caspofungin and the usage of these antifungals in different units were described in defined daily doses (DDD) per 1000 patient days...
November 9, 2016: Mycoses
https://www.readbyqxmd.com/read/27860332/ezetimibe-use-costs-and-adverse-events-in-australia
#17
Samantha A Hollingworth, Remo Ostino, Michael C David, Jennifer H Martin, Susan E Tett
AIM: To analyse the subsidised use and reported adverse events of ezetimibe, used to lower cholesterol, in Australia over the 11 years following its inclusion on the Pharmaceutical Benefits Scheme (PBS) in 2004. METHODS: Pharmacoepidemiological analysis of dispensed prescriptions from Medicare Australia. Adverse event data were obtained from the Therapeutic Goods Administration. Use was measured by the defined daily dose (DDD) per 1,000 population per day for each calendar year...
November 17, 2016: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/27855434/trends-in-the-outpatient-utilization-of-antipsychotic-drugs-in-the-city-of-zagreb-in-the-ten-year-period-as-a-tool-to-assess-drug-prescribing-rationality
#18
Marina Polić-Vižintin, Ingrid Tripković, Danijela Štimac, Zvonimir Šostar, Mirjana Orban
BACKGROUND: The aim was to determine distribution and trends in the outpatient utilization of antipsychotics to evaluate the rationality of antipsychotic drug prescribing during the ten year period. SUBJECTS AND METHODS: The epidemiological method of descriptive and analytical observation was used. Data on drug utilization from Zagreb Municipal Pharmacy were used to calculate the number of defined daily doses (DDD) and DDD per 1000 inhabitants per day (DDD/TID) using the World Health Organization Anatomical-Therapeutic-Chemical methodology...
December 2016: Psychiatria Danubina
https://www.readbyqxmd.com/read/27854109/effect-of-mono-or-bisegmental-lordosizing-fusion-on-short-term-global-and-index-sagittal-balance-a-radiographic-study
#19
Enrico Tessitore, Ilaria Melloni, Oliver P Gautschi, Gianluigi Zona, Karl Schaller, Pedro Berjano
BACKGROUND: Sagittal balance is widely recognized as an important outcome factor in reconstructive spinal surgery for lumbar degenerative conditions. However, its role in short segmental fixation is unknown. The aim of this study is to evaluate the preoperative and short-term postoperative spino-pelvic balance after short (1 or 2 levels) lordosizing lumbar fusion for degenerative disc disease (DDD). MATERIALS AND METHODS: Twenty-six consecutive patients (13 males and 13 females) undergoing mono- or bisegmental lordosizing lumbar fusion (XLIF/TLIF) for lumbar DDD were included in the study...
November 17, 2016: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27845232/women-do-not-fare-worse-than-men-after-lumbar-fusion-surgery-2-year-follow-up-results-from-4-780-prospectively-collected-patients-in-swespine-with-lumbar-degenerative-disc-disease-and-chronic-low-back-pain
#20
Jan Triebel, Greta Snellman, Bengt Sandén, Fredrik Strömqvist, Yohan Robinson
BACKGROUND CONTEXT: Proper patient selection is of outmost importance in surgical treatment of degenerative disc disease (DDD) with chronic low back pain (CLBP). Among other factors gender was previously found to influence lumbar fusion surgery outcome. PURPOSE: This study investigates whether gender affects clinical outcome after lumbar fusion. STUDY DESIGN: National registry cohort study PATIENT SAMPLE: Between 2001 and 2011, 2251 men and 2521 women were followed prospectively within the Swedish National Spine Registry (SWESPINE) after lumbar fusion surgery for DDD and CLBP...
November 11, 2016: Spine Journal: Official Journal of the North American Spine Society
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