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Sarcopenic obesity

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https://www.readbyqxmd.com/read/29460818/sarcopenic-obesity-and-health-outcomes-in-patients-seeking-weight-loss-treatment
#1
Jingjie Xiao, Angelina Cain, Sarah A Purcell, Michael J Ormsbee, Robert J Contreras, Jeong-Su Kim, Robert Thornberry, Dawn Springs, M Cristina Gonzalez, Carla M Prado
AIM: To investigate the prevalence of sarcopenic obesity (SO) and its association with health outcomes in patients seeking weight loss treatment from a bariatric center. METHODS: In this retrospective study, patients [≥18 years old, body mass index (BMI) ≥30 kg/m2 ] from the Tallahassee Memorial Bariatric Center and with baseline body composition assessment by bioelectrical impedance analysis were included. Fat mass index (FMI = fat mass/height2 ) and fat-free mass index (FFMI = fat free mass/height2 ) were calculated...
February 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29452783/oxidative-stress-is-increased-in-sarcopenia-and-associated-with-cardiovascular-disease-risk-in-sarcopenic-obesity
#2
Francesco Bellanti, Antonino D Romano, Aurelio Lo Buglio, Valeria Castriotta, Giuseppe Guglielmi, Antonio Greco, Gaetano Serviddio, Gianluigi Vendemiale
OBJECTIVES: To define whether circulating markers of oxidative stress correlate with sarcopenia in terms of glutathione balance and oxidative protein damage, and whether these biomarkers are associated with risk of cardiovascular disease (CVD). STUDY DESIGN: Population-based cross-sectional study. 115 out of 347 elderly subjects were classified as non-sarcopenic non-obese (NS-NO), sarcopenic non-obese (S-NO), non-sarcopenic obese (NS-O), and sarcopenic obese (S-O)...
March 2018: Maturitas
https://www.readbyqxmd.com/read/29417293/enhancing-evaluation-of-sarcopenia-in-patients-with-non-small-cell-lung-cancer-nsclc-by-assessing-skeletal-muscle-index-smi-at-the-first-lumbar-l1-level-on-routine-chest-computed-tomography-ct
#3
Alejandro Recio-Boiles, Jose N Galeas, Bernard Goldwasser, Karla Sanchez, Louise M W Man, Ryan D Gentzler, Jane Gildersleeve, Patricia J Hollen, Richard J Gralla
PURPOSE: Ongoing cancer cachexia trials evaluate sarcopenia by skeletal muscle index (SMI) at the L3 vertebrae level, commonly used as a standard. Routine chest CT institutional protocols widely differ in including L3. We investigated whether SMI at L1 assessment, rather than L3, would be reliable and more practicable for non-small cell lung cancer (NSCLC). METHODS: NSCLC patients with routine CT chest had SMI measurements performed at L1 using Slice-O-Matic software...
February 7, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29412438/the-vicious-cycle-of-myostatin-signaling-in-sarcopenic-obesity-myostatin-role-in-skeletal-muscle-growth-insulin-signaling-and-implications-for-clinical-trials
#4
L A Consitt, B C Clark
The age-related loss of skeletal muscle (sarcopenia) is a major health concern as it is associated with physical disability, metabolic impairments, and increased mortality. The coexistence of sarcopenia with obesity, termed 'sarcopenic obesity', contributes to skeletal muscle insulin resistance and the development of type 2 diabetes, a disease prevalent with advancing age. Despite this knowledge, the mechanisms contributing to sarcopenic obesity remain poorly understood, preventing the development of targeted therapeutics...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29396436/effects-of-elastic-band-exercise-on-lean-mass-and-physical-capacity-in-older-women-with-sarcopenic-obesity-a-randomized-controlled-trial
#5
Chun-De Liao, Jau-Yih Tsauo, Shih-Wei Huang, Jan-Wen Ku, Dun-Jen Hsiao, Tsan-Hon Liou
Sarcopenia is associated with loss of muscle mass as well as an increased risk of physical disability in elderly people. This study was aimed to investigate the effect of elastic band resistance training (ERT) on muscle mass and physical function in older women with sarcopenic obesity. A randomized controlled trial with an intention-to-treat analysis was conducted. A total of 56 women (mean ± SD age 67.3 ± 5.1 years) were randomly assigned to the experimental group receiving 12 weeks of ERT and to the control group receiving no exercise intervention...
February 2, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29357826/effects-of-resistance-training-on-body-composition-and-functional-capacity-among-sarcopenic-obese-residents-in-long-term-care-facilities-a-preliminary-study
#6
Shu-Ching Chiu, Rong-Sen Yang, Rea-Jeng Yang, Shu-Fang Chang
BACKGROUND: Aging-related loss of muscle and strength with increased adiposity is prevalent among older people in long-term care (LTC) facilities. Studies have shown that people with sarcopenic obesity (SO) are at high risk of declining physical performance. At present, no interventional studies on residents with SO in nursing homes have been conducted in the literature. The objectives of this study include appraising the changes in body composition and physical performance following resistance training among residents with SO in LTC facilities...
January 22, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29356607/effects-of-aerobic-and-resistance-exercise-on-metabolic-syndrome-sarcopenic-obesity-and-circulating-biomarkers-in-overweight-or-obese-survivors-of-breast-cancer-a-randomized-controlled-trial
#7
Christina M Dieli-Conwright, Kerry S Courneya, Wendy Demark-Wahnefried, Nathalie Sami, Kyuwan Lee, Thomas A Buchanan, Darcy V Spicer, Debu Tripathy, Leslie Bernstein, Joanne E Mortimer
Purpose Metabolic syndrome is associated with an increased risk of cardiovascular disease, type 2 diabetes, and breast cancer recurrence in survivors of breast cancer. This randomized controlled trial assessed the effects of a 16-week combined aerobic and resistance exercise intervention on metabolic syndrome, sarcopenic obesity, and serum biomarkers among ethnically diverse, sedentary, overweight, or obese survivors of breast cancer. Methods Eligible survivors of breast cancer (N = 100) were randomly assigned to exercise (n = 50) or usual care (n = 50)...
January 22, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29349902/association-between-pre-sarcopenia-sarcopenia-and-bone-mineral-density-in-patients-with-chronic-hepatitis-c
#8
Tatiana Bering, Kiara G D Diniz, Marta Paula P Coelho, Diego A Vieira, Maria Marta S Soares, Adriana M Kakehasi, Maria Isabel T D Correia, Rosângela Teixeira, Dulciene M M Queiroz, Gifone A Rocha, Luciana D Silva
BACKGROUND: Preserved skeletal muscle is essential for the maintenance of healthy bone. Loss of bone mineral density (BMD) and muscle strength, considered a predictor of BMD, have been demonstrated in patients with cirrhosis, but they are poorly studied in chronic hepatitis C (CHC) without cirrhosis. Thus, we aimed to evaluate the prevalence of low BMD and its association with body composition, muscle strength, and nutritional status in CHC. METHODS: One hundred and four subjects [mean age, 50...
January 19, 2018: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/29312971/impact-of-sarcopenic-overweight-on-the-outcomes-after-living-donor-liver-transplantation
#9
Ahmed Hammad, Toshimi Kaido, Yuhei Hamaguchi, Shinya Okumura, Atsushi Kobayashi, Hisaya Shirai, Naoko Kamo, Shintaro Yagi, Shinji Uemoto
Background: The effect of body composition disturbances has been recently in focus. Sarcopenic obesity, a co-occurrence of low muscle mass and high body fat was reportedly predictive of high mortality in patients with cirrhosis. However, the impact of the interacting sarcopenia and overweight on the outcomes after liver transplantation is still unclear. Methods: We evaluated 200 patients undergoing adult-to-adult living donor liver transplantation at our institution between January 2008 and November 2013 classified according to BMI and psoas muscle index (PMI) on admission to transplant into 4 subgroups; sarcopenic overweight (SO), sarcopenic non-overweight (SN), non-sarcopenic overweight and non-sarcopenic non-overweight (NN)...
December 2017: Hepatobiliary Surgery and Nutrition
https://www.readbyqxmd.com/read/29304744/a-randomised-controlled-intervention-study-investigating-the-efficacy-of-carotenoid-rich-fruits-and-vegetables-and-extra-virgin-olive-oil-on-attenuating-sarcopenic-symptomology-in-overweight-and-obese-older-adults-during-energy-intake-restriction-protocol-paper
#10
Anthony Villani, Hattie Wright, Gary Slater, Jonathan Buckley
BACKGROUND: Weight loss interventions have not been advocated for overweight/obese older adults due to potential loss of skeletal muscle and strength impacting on physical function with potential loss of independence. Carotenoids and polyphenols are inversely associated with sarcopenic symptomology. This paper reports the protocol of a study evaluating the efficacy of a high-protein, energy restricted diet rich in carotenoids and polyphenols on body composition, muscle strength, physical performance and quality of life in overweight and obese older adults...
January 5, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29290364/association-of-sarcopenic-obesity-predicted-by-anthropometric-measurements-and-24-y-all-cause-mortality-in-elderly-men-the-kuakini-honolulu-heart-program
#11
Kiyoshi Sanada, Randi Chen, Bradley Willcox, Tomoyuki Ohara, Aida Wen, Cody Takenaka, Kamal Masaki
OBJECTIVE: The aim of this study was to investigate the association between anthropometric measurements of sarcopenic obesity and all-cause mortality. METHODS: The study included 2309 Japanese-American men ages 71 to 93 y. Mortality data were available for up to 24 y of follow-up. Sarcopenic obesity defined by three patterns of obesity indexes (body mass index [BMI], percent body fat [%BF] and waist circumference [WC]) and skeletal muscle index estimated by anthropometric measurements...
February 2018: Nutrition
https://www.readbyqxmd.com/read/29290349/dxa-assessed-changes-in-body-composition-in-obese-women-following-two-different-weight-loss-programs
#12
Federico Ponti, Valentina Soverini, Andrea Plazzi, Maria Pilar Aparisi Gómez, Daniele Mercatelli, Giuseppe Guglielmi, Giuseppe Battista, Giulio Marchesini, Alberto Bazzocchi
OBJECTIVE: Changes in body composition during weight loss programs might have a significant effect on long-term results. The aim of this study was to test these changes by dual energy x-ray absorptiometry (DXA) in obese women enrolled into two different weight loss medical programs. METHODS: We prospectively studied 71 women assigned to either an intensive 3-mo cognitive-behavioral therapy (CBT) or a 1-mo nutritional counseling plan (NCP). All patients underwent DXA whole-body scan before treatment and after 3, 6, and 12 mo...
February 2018: Nutrition
https://www.readbyqxmd.com/read/29277040/associations-of-components-of-sarcopenic-obesity-with-bone-health-and-balance-in-older-adults
#13
David Scott, Catherine Shore-Lorenti, Lachlan McMillan, Jakub Mesinovic, Ross A Clark, Alan Hayes, Kerrie M Sanders, Gustavo Duque, Peter R Ebeling
OBJECTIVES: To determine characteristics of sarcopenic obesity that are independently associated with bone health and balance in older adults. STUDY DESIGN: Cross-sectional study of 168 community-dwelling older adults (mean age 67.7 ± 8.4 years; 55% women). MAIN OUTCOME MEASURES: Appendicular lean mass (ALM), whole-body areal BMD (aBMD) and body fat percentage were assessed by dual-energy X-ray absorptiometry. Peripheral quantitative computed tomography assessed muscle density and cortical volumetric BMD (vBMD), area, thickness, and strength-strain index (SSI) at 66% tibial length...
December 16, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29276063/is-sarcopenia-and-sarcopenic-obesity-associated-with-clinical-and-pathological-outcomes-in-patients-undergoing-radical-nephroureterectomy
#14
Neil J Kocher, Syed Jafri, Samyuktha Balabhadra, Erik Lehman, Jacob Gardner, Kanupriya Vijay, Nabeel Sarwani, Jay D Raman
PURPOSE: To investigate the association between sarcopenia and sarcopenic obesity on clinical, perioperative, and oncologic outcomes in patients with upper-tract urothelial carcinoma (UTUC) undergoing radical nephroureterectomy (RNU). METHODS: Retrospective review of our institutional UTUC database was performed to identify all patients who underwent radical nephroureterectomy from 2002-2016. Skeletal Muscle Index (SMI) was measured at the L3 vertebral level and standardized according to patient height (cm2/m2)...
December 21, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29234200/nutrition-and-muscle-in-cirrhosis
#15
REVIEW
Anil C Anand
As the cirrhosis progresses, development of complication like ascites, hepatic encephalopathy, variceal bleeding, kidney dysfunction, and hepatocellular carcinoma signify increasing risk of short term mortality. Malnutrition and muscle wasting (sarcopenia) is yet other complications that negatively impact survival, quality of life, and response to stressors, such as infection and surgery in patients with cirrhosis. Conventionally, these are not routinely looked for, because nutritional assessment can be a difficult especially if there is associated fluid retention and/or obesity...
December 2017: Journal of Clinical and Experimental Hepatology
https://www.readbyqxmd.com/read/29234165/short-physical-performance-battery-for-cardiovascular-disease-inpatients-implications-for-critical-factors-and-sarcopenia
#16
Tomohiro Yasuda, Toshiaki Nakajima, Tatsuya Sawaguchi, Naohiro Nozawa, Tomoe Arakawa, Reiko Takahashi, Yuta Mizushima, Satoshi Katayanagi, Kazuhisa Matsumoto, Shigeru Toyoda, Teruo Inoue
We examined the relationship between Short Physical Performance Battery (SPPB) and clinical and laboratory factors and the effect of sarcopenia and sarcopenic obesity (SO) on clinical and laboratory factors for cardiovascular disease (CVD) inpatients. CVD male (n = 318) and female (n = 172) inpatients were recruited. A stepwise multiple-regression analysis was performed to predict total SPPB scores and assess clinical and laboratory factors (physical characteristics, functional and morphological assessments, etc...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29231963/body-composition-in-long-term-survivors-of-acute-lymphoblastic-leukemia-diagnosed-in-childhood-and-adolescence-a-focus-on-sarcopenic-obesity
#17
Christopher J C Marriott, Lesley F Beaumont, Troy H Farncombe, Amy N Cranston, Uma H Athale, Valerie N Yakemchuk, Colin E Webber, Ronald D Barr
BACKGROUND: The late effects of treatment for acute lymphoblastic leukemia (ALL) include disordered body composition, especially obesity. Less attention has been focused on the loss of skeletal muscle mass (SMM) and the combined morbidity of sarcopenic obesity. METHODS: A cross-sectional study of body composition was undertaken via dual-energy x-ray absorptiometry in 75 long-term survivors of ALL (more than 10 years after the diagnosis). Measures were obtained of the fat mass (FM), fat-free mass (equivalent to the lean body mass [LBM]), and whole-body bone mineral content...
December 12, 2017: Cancer
https://www.readbyqxmd.com/read/29217429/association-of-platelet-count-with-sarcopenic-obesity-in-postmenopausal-women-a-nationwide-population-based-study
#18
Woo-Jin Park, Dong-Hyuk Jung, Ji-Won Lee, Jae-Yong Shim, Yu-Jin Kwon
OBJECTIVES: The aim of this study was to examine the relationship between platelet count and sarcopenic obesity in postmenopausal women. METHOD: This cross-sectional study was conducted using nationally representative data. A total of 2810 postmenopausal women who participated in the 2008-2011 Korea National Health and Nutrition Examination Survey were included in this study. Sarcopenic obesity was defined by a sarcopenia criterion and an obesity criterion. Platelet counts were divided into quartiles as follows: Q, 150-222; Q2, 223-257; Q3, 258-294, and Q4, 295-450 (103/μl)...
December 5, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29209478/association-between-sarcopenia-and-dipstick-proteinuria-in-the-elderly-population-the-korea-national-health-and-nutrition-examination-surveys-2009-2011
#19
Duna Hwang, Mi-Ryung Cho, Minyong Choi, Sang Hyun Lee, Youngmin Park
Background: Sarcopenia and proteinuria are significant health difficulties in the elderly; however, few studies have investigated their relationship. In this study, we investigated the association between sarcopenia and proteinuria in Korean subjects over 60 years old. Methods: We included data from the Korean National Health and Nutrition Examination Survey, a cross-sectional, nationally representative survey conducted from 2009 to 2011 (n=4,008). Sarcopenia was defined using appendicular skeletal muscle mass as a percentage of body weight...
November 2017: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/29169576/sarcopenia-and-sarcopenic-obesity-in-spanish-community-dwelling-middle-aged-and-older-women-association-with-balance-confidence-fear-of-falling-and-fall-risk
#20
Agustín Aibar-Almazán, Antonio Martínez-Amat, David Cruz-Díaz, José D Jiménez-García, Alexander Achalandabaso, Indalecio Sánchez-Montesinos, Manuel de la Torre-Cruz, Fidel Hita-Contreras
OBJECTIVES: To analyze the association of sarcopenia, obesity, and sarcopenic obesity (SO) with fear of falling (FoF) and balance confidence in a Spanish sample of middle-aged and older community-dwelling women. STUDY DESIGN AND OUTCOME MEASURES: A total of 235 women (69.21±7.56 years) participated in this study. Body composition (bioelectrical impedance analysis), hand-grip strength, and physical performance (gait speed) were evaluated for the diagnosis of sarcopenia, obesity, and SO...
January 2018: Maturitas
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