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Sarcopenic obesity

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https://www.readbyqxmd.com/read/28615264/is-the-whole-not-greater-than-the-sum-of-its-parts-the-case-of-sarcopenic-obesity
#1
John A Batsis, Summer B Cook
No abstract text is available yet for this article.
June 14, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28591061/effects-of-elastic-resistance-exercise-on-body-composition-and-physical-capacity-in-older-women-with-sarcopenic-obesity-a-consort-compliant-prospective-randomized-controlled-trial
#2
Chun-De Liao, Jau-Yih Tsauo, Li-Fong Lin, Shih-Wei Huang, Jan-Wen Ku, Lin-Chuan Chou, Tsan-Hon Liou
BACKGROUND: Sarcopenia is associated with loss of muscle mass and an increased risk of physical disability in elderly people. However, the prevalence of sarcopenia has increased in obese elderly populations. The purpose of this study was to identify the clinical efficacy of elastic resistance exercise training (RET) in patients with sarcopenic obesity. METHODS: This study was conducted at the rehabilitation center of a university-based teaching hospital and was designed as a prospective and randomized controlled trial with an intention-to-treat analysis...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28577161/morphological-and-qualitative-characteristics-of-the-quadriceps-muscle-of-community-dwelling-older-adults-based-on-ultrasound-imaging-classification-using-latent-class-analysis
#3
Hisashi Kawai, Takeshi Kera, Ryo Hirayama, Hirohiko Hirano, Yoshinori Fujiwara, Kazushige Ihara, Motonaga Kojima, Shuichi Obuchi
BACKGROUND: Muscle thickness and echo intensity measured using ultrasound imaging represent both increased muscle volume and connective tissue accumulation. In combination, these ultrasound measurements can be utilized for assessing sarcopenia in community-dwelling older adults. AIMS: This study aimed to determine whether morphological and qualitative characteristics classified by quadriceps muscle thickness and echo intensity measured using ultrasound are associated with muscle strength, physical function, and sarcopenia in community-dwelling older adults...
June 2, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28542196/using-relative-handgrip-strength-to-identify-children-at-risk-of-sarcopenic-obesity
#4
Michal Steffl, Jan Chrudimsky, James J Tufano
Identifying children at risk of developing childhood sarcopenic obesity often requires specialized equipment and costly testing procedures, so cheaper and quicker methods would be advantageous, especially in field-based settings. The purpose of this study was to determine the relationships between the muscle-to-fat ratio (MFR) and relative handgrip strength, and to determine the ability of handgrip strength relative to body mass index (grip-to-BMI) to identify children who are at risk of developing sarcopenic obesity...
2017: PloS One
https://www.readbyqxmd.com/read/28539380/sarcopenic-obesity-weight-loss-and-mortality-the-english-longitudinal-study-of-ageing
#5
Mark Hamer, Gary O'Donovan
Background: Age-related sarcopenia describes the loss of muscle strength and often accompanies an increase in adiposity in the elderly.Objective: We examined the association of sarcopenic obesity and changes in muscle strength and weight with the risk of mortality.Design: Participants (n = 6864) were community-dwelling men and women (45.6% men; 54.4% women; mean ± SD age: 66.2 ± 9.5 y) from the English Longitudinal Study of Ageing. Handgrip strength and body mass index (BMI; in kg/m(2)) were measured at baseline and at a 4-y follow-up...
May 24, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28539168/effectiveness-of-nutritional-supplementation-on-sarcopenia-and-recovery-in-hip-fracture-patients-a-multi-centre-randomized-trial
#6
Vincenzo Malafarina, Francisco Uriz-Otano, Concetta Malafarina, J Alfredo Martinez, M Angeles Zulet
BACKGROUND AND OBJECTIVES: Functional deterioration and reduced mobility in elderly patients with a hip fracture are associated with a loss of both muscle mass and function (sarcopenia). The aim of this study was to assess whether oral nutritional supplementation (ONS) improves muscle mass and nutritional markers (BMI, proteins) in elderly patients with hip fracture. METHODS: Patients aged 65 years and over with hip fractures admitted to either of two rehabilitation facilities were included...
July 2017: Maturitas
https://www.readbyqxmd.com/read/28531567/impact-of-body-composition-parameters-on-clinical-outcomes-in-patients-with-metastatic-castrate-resistant-prostate-cancer-treated-with-docetaxel
#7
Samantha J Cushen, Derek G Power, Kevin P Murphy, Ray McDermott, Brendan T Griffin, Marvin Lim, Louise Daly, Peter MacEneaney, Kathleen O' Sullivan, Carla M Prado, Aoife M Ryan
BACKGROUND: Body composition may influence clinical outcomes of certain chemotherapeutic agents. We examined the prognostic significance of skeletal muscle mass and adipose tissue on docetaxel toxicity and overall survival in patients with metastatic castrate resistant prostate cancer (mCRPC). METHODS: A retrospective review of patients medical records with mCRPC, treated with docetaxel was conducted. Body composition parameters (skeletal muscle mass, muscle attenuation [MA], visceral and subcutaneous adipose tissue) were measured at L3 by computed tomography (CT) and defined using previously established cut points...
June 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28528340/evaluation-of-hypocaloric-diet-with-protein-supplementation-in-middle-aged-sarcopenic-obese-women-a-pilot-study
#8
Rosa Sammarco, Maurizio Marra, Maria Luisa Di Guglielmo, Marianna Naccarato, Franco Contaldo, Eleonora Poggiogalle, Lorenzo Maria Donini, Fabrizio Pasanisi
OBJECTIVE: The aim of this study was to evaluate the efficacy of a nutritional program, which is characterized by a different modulation of proteins, in adult patients with sarcopenic obesity. METHODS: We studied 18 obese women aged 41-74 years. Obesity was diagnosed as fat mass > 34.8% and sarcopenia was defined when lean body mass was <90% of the subject's ideal fat free mass. All subjects were randomly assigned to different nutritional interventions: Hypocaloric diet plus placebo (A) and hypocaloric high-protein diet (1...
May 20, 2017: Obesity Facts
https://www.readbyqxmd.com/read/28506965/explaining-the-obesity-paradox-the-association-between-body-composition-and-colorectal-cancer-survival-c-scans-study
#9
Bette J Caan, Jeffrey A Meyerhardt, Candyce H Kroenke, Stacey Alexeeff, Jingjie Xiao, Erin Weltzien, Elizabeth Cespedes Feliciano, Adrienne L Castillo, Charles P Quesenberry, Marilyn L Kwan, Carla M Prado
Background: Body composition may partially explain the U-shaped association between body mass index (BMI) and colorectal cancer survival.Methods: Muscle and adiposity at colorectal cancer diagnosis and survival were examined in a retrospective cohort using Kaplan-Meier curves, multivariable Cox regression, and restricted cubic splines in 3,262 early-stage (I-III) male (50%) and female (50%) patients. Sarcopenia was defined using optimal stratification and sex- and BMI-specific cut points. High adiposity was defined as the highest tertile of sex-specific total adipose tissue (TAT)...
May 15, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28464999/light-coffee-consumption-is-protective-against-sarcopenia-but-frequent-coffee-consumption-is-associated-with-obesity-in-korean-adults
#10
Jeong-Hyeon Kim, Yong Soon Park
Few studies have examined the effects of coffee on body composition in the general population. In this cross-sectional study, we hypothesized that coffee consumption is protective against obesity and sarcopenia in Korean adults. The study included 6906 subjects aged ≥40 years who participated in the Korean National Health and Nutrition Examination Survey in 2009-2010. Body composition was measured using dual-energy x-ray absorptiometry, and obesity was determined according to the body mass index (BMI) and waist circumference (WC)...
May 2017: Nutrition Research
https://www.readbyqxmd.com/read/28439567/sarcopenia-obesity-and-mortality-in-us-adults-with-and-without-chronic-kidney-disease
#11
Lagu Androga, Deep Sharma, Afolarin Amodu, Matthew K Abramowitz
INTRODUCTION: In pre-dialysis chronic kidney disease (CKD), the association of muscle mass with mortality is poorly defined, and no study has examined outcomes related to the co-occurrence of low muscle mass and excess adiposity (sarcopenic-obesity). Methods: We examined abnormalities of muscle and fat mass in adult participants of the National Health and Nutrition Examination Survey 1999-2004. We determined whether associations of body composition with all-cause mortality differed between participants with CKD compared to those without...
March 2017: KI Reports
https://www.readbyqxmd.com/read/28421144/prevalence-of-sarcopenic-obesity-in-adults-with-class-ii-iii-obesity-using-different-diagnostic-criteria
#12
Carlene A Johnson Stoklossa, Arya M Sharma, Mary Forhan, Mario Siervo, Raj S Padwal, Carla M Prado
Background/Objective. Sarcopenic obesity (SO) is a hidden condition of reduced lean soft tissue (LST) in context of excess adiposity. SO is most commonly reported in older adults and both its risk and prevalence increase with age. A variety of body composition indices and cut points have been used to define this condition, leading to conflicting prevalence and risk prediction. Here, we investigate variability in the prevalence of SO in an adult sample of individuals with class II/III obesity (BMI ≥ 35 kg/m(2)) using different diagnostic criteria...
2017: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/28410342/sarcopenia-is-common-in-overweight-patients-with-inflammatory-bowel-disease-and-may-predict-need-for-surgery
#13
Dawn W Adams, Shelly Gurwara, Heidi J Silver, Sara N Horst, Dawn B Beaulieu, David A Schwartz, Douglas L Seidner
BACKGROUND: Inflammatory bowel disease (IBD) is associated with altered body composition, such as low muscle mass, which affects clinical outcomes. Body composition changes in overweight patients with IBD are less understood. The study aim was to determine the prevalence of sarcopenic overweight and obese patients in a cohort of patients with IBD starting new anti-tumor necrosis factor-α therapy and examine differences in response. METHODS: This is a retrospective review of patients with IBD starting a new anti-tumor necrosis factor-α medication that had computed tomography within 3 months of initiation...
July 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28407041/effects-of-low-muscle-mass-on-albuminuria-and-chronic-kidney-disease-in-patients-with-type-2-diabetes-the-korean-sarcopenic-obesity-study-ksos
#14
Hye Soo Chung, Soon Young Hwang, Ju Hee Choi, Hyun Jung Lee, Hye Jin Yoo, Ji-A Seo, Sin Gon Kim, Nan Hee Kim, Dong Seop Choi, Sei Hyun Baik, Kyung Mook Choi
Background: Previous studies have shown that chronic kidney disease (CKD) is associated with accelerated loss of skeletal muscle in patients on dialysis. However, the relationships of sarcopenia with albuminuria and early-stage CKD in patients with type 2 diabetes have not been examined. Methods: We analyzed diabetic subgroup data from 409 patients with type 2 diabetes from the Korean Sarcopenic Obesity Study (KSOS). Sarcopenia was defined as a skeletal muscle mass index (SMI; SMI [%] = total skeletal muscle mass [kg]/weight [kg] × 100) less than 2 SD below the sex-specific mean for a younger reference group...
April 12, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28396974/sarcopenic-overweight-is-associated-with-early-acute-limiting-toxicity-of-anti-pd1-checkpoint-inhibitors-in-melanoma-patients
#15
Heidelberger Valentine, Goldwasser François, Kramkimel Nora, Jouinot Anne, Huillard Olivier, Boudou-Rouquette Pascaline, Chanal Johan, Arrondeau Jennifer, Franck Nathalie, Alexandre Jérôme, Blanchet Benoît, Leroy Karen, Avril Marie-Françoise, Dupin Nicolas, Aractingi Sélim
Little is known on factors predicting toxicity of anti-PD1 checkpoint inhibitors. Sarcopenic obesity is associated with increased acute toxicity of cytotoxic agents and targeted therapies. We explored whether body composition also influenced the occurrence of early acute limiting toxicity (ALT) of anti-PD1 in melanoma patients. This is a monocentric, retrospective study analyzing toxicity outcome in consecutive melanoma patients treated with nivolumab or pembrolizumab. Various parameters linked to the patient or the disease status have been analysed...
April 10, 2017: Investigational New Drugs
https://www.readbyqxmd.com/read/28374624/elevated-serum-leptin-levels-are-associated-with-low-vitamin-d-sarcopenic-obesity-poor-muscle-strength-and-physical-performance-in-knee-osteoarthritis
#16
Pacharee Manoy, Wilai Anomasiri, Pongsak Yuktanandana, Aree Tanavalee, Srihatach Ngarmukos, Thanathep Tanpowpong, Sittisak Honsawek
CONTEXT: The associations between serum leptin, vitamin D status, sarcopenic obesity, muscle strength and physical performance in osteoarthritis (OA) remain uncertain. OBJECTIVE: To analyse the relationships between serum leptin, vitamin D status, muscle strength and physical performance in OA patients. METHODS: A total of 208 knee OA patients were enrolled. Serum leptin, vitamin D, muscle strength and physical performance were evaluated. RESULTS: OA patients with sarcopenic obesity had significantly higher serum leptin levels than those with non-sarcopenic obesity...
April 19, 2017: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/28364311/erratum-to-sarcopenia-and-sarcopenic-obesity-in-comparison-prevalence-metabolic-profile-and-key-differences-a-cross-sectional-study-in-italian-hospitalized-elderly
#17
Simone Perna, Gabriella Peroni, Milena Anna Faliva, Arianna Bartolo, Maurizio Naso, Alessandra Miccono, Mariangela Rondanelli
No abstract text is available yet for this article.
March 31, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28358295/body-adiposity-index-but-not-visceral-adiposity-index-correlates-with-inflammatory-markers-in-sarcopenic-obese-elderly-women
#18
Maurílio Tiradentes Dutra, André Bonadias Gadelha, Otávio Toledo Nóbrega, Ricardo Moreno Lima
Background/Study Context: The association of body adiposity index (BAI) and visceral adiposity index (VAI) with inflammatory markers has yet to be understood. The aim of this work was to investigate the association of BAI and VAI with inflammatory markers in elderly women with sarcopenic obesity (SO). METHODS: A total of 130 women (age: 66.7 ± 5.2 years) underwent body composition analysis by dual-energy x-ray absorptiometry (DEXA). Volunteers were classified according to SO definition...
May 2017: Experimental Aging Research
https://www.readbyqxmd.com/read/28346492/dual-energy-x-ray-absorptiometry-body-composition-reference-values-of-limbs-and-trunk-from-nhanes-1999-2004-with-additional-visualization-methods
#19
Benjamin J Hinton, Bo Fan, Bennett K Ng, John A Shepherd
Body Mass Index has traditionally been used as a measure of health, but Fat Mass Index (FMI) and Lean Mass Index (LMI) have been shown to be more predictive of mortality and health risk. Total body FMI and LMI reference curves have particularly been useful in quantifying sarcopenia and sarcopenic obesity. Research has shown regional composition has significant associations to health outcomes. We derived FMI and LMI reference curves of the regions of the body (leg, arm, and trunk) for 15,908 individuals in the 1999-2004 National Health and Nutrition Examination Survey data for each sex and ethnicity using the Lambda-Mu-Sigma (LMS) method and developed software to visualize this regional composition...
2017: PloS One
https://www.readbyqxmd.com/read/28343799/characterization-of-deficits-across-the-spectrum-of-motor-abilities-in-dialysis-patients-and-the-impact-of-sarcopenic-overweight-and-obesity
#20
Maja Bučar Pajek, Jernej Pajek
BACKGROUND & AIMS: Physical performance deficits in kidney failure predict mortality and quality of life. We aimed to quantify deficits in multiple motor abilities, investigate associations of lean and fat tissue content with test results and analyzed performance of sarcopenic individuals with adipose tissue excess. METHODS: Ninety hemodialysis patients and 140 healthy controls performed 6-minute walk test, gait speed measurement, sit-to-stand and time up and go tests, upper extremity handgrip and tapping tests, Stork balance and forward bend flexibility tests...
March 16, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
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