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https://www.readbyqxmd.com/read/27911347/smartphone-applications-for-immersive-virtual-reality-therapy-for-internet-addiction-and-internet-gaming-disorder
#1
Melvyn W B Zhang, Roger C M Ho
There have been rapid advances in technologies over the past decade and virtual reality technology is an area which is increasingly utilized as a healthcare intervention in many disciplines including that of Medicine, Surgery and Psychiatry. In Psychiatry, most of the current interventions involving the usage of virtual reality technology is limited to its application for anxiety disorders. With the advances in technology, Internet addiction and Internet gaming disorders are increasingly prevalent. To date, these disorders are still being treated using conventional psychotherapy methods such as cognitive behavioural therapy...
November 25, 2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/27911234/ventriculostomy-associated-hemorrhage-a-risk-assessment-by-radiographic-simulation
#2
Faith C Robertson, Muhammad M Abd-El-Barr, Srinivasan Mukundan, William B Gormley
OBJECTIVE Ventriculostomy entry sites are commonly selected by freehand estimation of Kocher's point or approximations from skull landmarks and a trajectory toward the ipsilateral frontal horn of the lateral ventricles. A recognized ventriculostomy complication is intracranial hemorrhage from cortical vessel damage; reported rates range from 1% to 41%. In this report, the authors assess hemorrhagic risk by simulating traditional ventriculostomy trajectories and using CT angiography (CTA) with venography (CTV) data to identify potential complications, specifically from cortical draining veins...
December 2, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27909833/verification-of-a-virtual-fields-method-to-extract-the-mechanical-properties-of-human-optic-nerve-head-tissues-in-vivo
#3
Liang Zhang, Sri Gowtham Thakku, Meghna R Beotra, Mani Baskaran, Tin Aung, James C H Goh, Nicholas G Strouthidis, Michael J A Girard
We aimed to verify a custom virtual fields method (VFM) to estimate the patient-specific biomechanical properties of human optic nerve head (ONH) tissues, given their full-field deformations induced by intraocular pressure (IOP). To verify the accuracy of VFM, we first generated 'artificial' ONH displacements from predetermined (known) ONH tissue biomechanical properties using finite element analysis. Using such deformations, if we are able to match back the known biomechanical properties, it would indicate that our VFM technique is accurate...
December 1, 2016: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/27909659/reliability-of-the-planned-pedicle-screw-trajectory-versus-the-actual-pedicle-screw-trajectory-using-intra-operative-3d-ct-and-image-guidance
#4
Catherine A Miller, Charles G Ledonio, Matthew A Hunt, Farhan Siddiq, David W Polly
BACKGROUND: Technological advances, including navigation, have been made to improve safety and accuracy of pedicle screw fixation. We evaluated the accuracy of the virtual screw placement (Stealth projection) compared to actual screw placement (intra-operative O-Arm) and examined for differences based on the distance from the reference frame. METHODS: A retrospective evaluation of prospectively collected data was conducted from January 2013 to September 2013. We evaluated thoracic and lumbosacral pedicle screws placed using intraoperative O-arm and Stealth navigation by obtaining virtual screw projections and intraoperative O-arm images after screw placement...
2016: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/27909424/virtual-reality-as-an-embodied-tool-to-enhance-episodic-memory-in-elderly
#5
Claudia Repetto, Silvia Serino, Manuela Macedonia, Giuseppe Riva
No abstract text is available yet for this article.
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27909252/nurses-as-antibiotic-brokers-institutionalized-praxis-in-the-hospital
#6
Alex Broom, Jennifer Broom, Emma Kirby, Graham Scambler
We are likely moving rapidly toward a post-antibiotic era, as a result of escalating antimicrobial resistance, rapidly declining antibiotic production and profligate overuse. Hitherto research has almost exclusively focused on doctors' prescribing, with nurses' roles in antibiotic use remaining virtually invisible. Drawing on interviews with 30 nurses, we focus on nurses as brokers of doctors' antibiotic decisions, nursing capacity to challenge doctors' decisions, and, "back stage" strategies for circumnavigating organizational constraints...
November 30, 2016: Qualitative Health Research
https://www.readbyqxmd.com/read/27909096/excitatory-hindbrain-forebrain-communication-is-required-for-cisplatin-induced-anorexia-and-weight-loss
#7
Amber L Alhadeff, Ruby A Holland, Huiyuan Zheng, Linda Rinaman, Harvey J Grill, Bart C De Jonghe
: Cisplatin chemotherapy is commonly used to treat cancer despite severe energy balance side effects. In rats, cisplatin activates nucleus tractus solitarius (NTS) projections to the lateral parabrachial nucleus (lPBN), and calcitonin-gene related peptide (CGRP) projections from the lPBN to the central nucleus of the amygdala (CeA). We previously demonstrated that CeA glutamate receptor signaling mediates cisplatin-induced anorexia and body weight loss. Here, we use neuroanatomical tracing, immunofluorescence and confocal imaging to demonstrate that virtually all NTS→lPBN and lPBN→CeA CGRP projections co-express vesicular glutamate transporter 2 (VGLUT2), providing evidence that excitatory projections mediate cisplatin-induced energy balance dysregulation...
December 1, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27908973/environmental-public-health-tracking-a-cost-effective-system-for-characterizing-the-sources-distribution-and-public-health-impacts-of-environmental-hazards
#8
P J Saunders, J D Middleton, G Rudge
BACKGROUND: The contemporary environment is a complex of interactions between physical, biological, socio-economic systems with major impacts on public health. However, gaps in our understanding of the causes, extent and distribution of these effects remain. The public health community in Sandwell West Midlands has collaborated to successfully develop, pilot and establish the first Environmental Public Health Tracking (EPHT) programme in Europe to address this 'environmental health gap' through systematically linking data on environmental hazards, exposures and diseases...
December 1, 2016: Journal of Public Health
https://www.readbyqxmd.com/read/27908936/genome-editing-technologies-principles-and-applications
#9
REVIEW
Thomas Gaj, Shannon J Sirk, Sai-Lan Shui, Jia Liu
Targeted nucleases have provided researchers with the ability to manipulate virtually any genomic sequence, enabling the facile creation of isogenic cell lines and animal models for the study of human disease, and promoting exciting new possibilities for human gene therapy. Here we review three foundational technologies-clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9), transcription activator-like effector nucleases (TALENs), and zinc-finger nucleases (ZFNs)...
December 1, 2016: Cold Spring Harbor Perspectives in Biology
https://www.readbyqxmd.com/read/27908844/quittr-the-design-of-a-video-game-to-support-smoking-cessation
#10
Ivan Bindoff, Kristy de Salas, Gregory Peterson, Tristan Ling, Ian Lewis, Lindsay Wells, Peter Gee, Stuart G Ferguson
BACKGROUND: Smoking is recognized as the largest, single, preventable cause of death and disease in the developed world. While the majority of smokers report wanting to quit, and many try each year, smokers find it difficult to maintain long-term abstinence. Behavioral support, such as education, advice, goal-setting, and encouragement, is known to be beneficial in improving the likelihood of succeeding in a quit attempt, but it remains difficult to effectively deliver this behavioral support and keep the patient engaged with the process for a sufficient duration...
December 1, 2016: JMIR Serious Games
https://www.readbyqxmd.com/read/27908220/pluripotent-stem-cells-the-last-10-years
#11
Erin A Kimbrel, Robert Lanza
Pluripotent stem cells (PSCs) can differentiate into virtually any cell type in the body, making them attractive for both regenerative medicine and drug discovery. Over the past 10 years, technological advances and innovative platforms have yielded first-in-man PSC-based clinical trials and opened up new approaches for disease modeling and drug development. Induced PSCs have become the foremost alternative to embryonic stem cells and accelerated the development of disease-in-a-dish models. Over the years and with each new discovery, PSCs have proven to be extremely versatile...
December 2, 2016: Regenerative Medicine
https://www.readbyqxmd.com/read/27908072/perceptual-attributes-for-the-comparison-of-head-related-transfer-functions
#12
Laurent S R Simon, Nick Zacharov, Brian F G Katz
The benefit of using individual head-related transfer functions (HRTFs) in binaural audio is well documented with regards to improving localization precision. However, with the increased use of binaural audio in more complex scene renderings, cognitive studies, and virtual and augmented reality simulations, the perceptual impact of HRTF selection may go beyond simple localization. In this study, the authors develop a list of attributes which qualify the perceived differences between HRTFs, providing a qualitative understanding of the perceptual variance of non-individual binaural renderings...
November 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27908017/symmetry-restoring-bifurcations-and-quasiperiodic-chaos-induced-by-a-new-intermittency-in-a-vibro-impact-system
#13
Yuan Yue, Pengcheng Miao, Jianhua Xie, Grebogi Celso
Quasiperiodic chaos (QC), which is a combination of quasiperiodic sets and a chaotic set, is uncovered in the six dimensional Poincaré map of a symmetric three-degree of freedom vibro-impact system. Accompanied by symmetry restoring bifurcation, this QC is the consequence of a novel intermittency that occurs between two conjugate quasiperiodic sets and a chaotic set. The six dimensional Poincaré map P is the 2-fold composition of another virtual implicit map Q, yielding the symmetry of the system. Map Q can capture two conjugate attractors, which is at the core of the dynamics of the vibro-impact system...
November 2016: Chaos
https://www.readbyqxmd.com/read/27907981/use-of-social-media-in-education-among-medical-students-in-saudi-arabia
#14
Anas Khaleel Alsuraihi, Ahmed Saeed Almaqati, Sultan Adnan Abughanim, Nisreen Abdulrahman Jastaniah
PURPOSE: Social media (SM), a virtual place where people can share, exchange, and communicate their ideas and knowledge, has become the new trend in communication and learning. This study aims to explore Saudi Arabian medical students' usage of SM and to discover the most common resources used in medical education. Furthermore, it aims to illustrate students' belief about the influence of SM on their learning. METHODS: This cross-sectional study administered validated questionnaires to medical students from different universities in Saudi Arabia, via emails, Twitter, Facebook, and short message service...
December 2016: Korean Journal of Medical Education
https://www.readbyqxmd.com/read/27907105/epidemiology-of-brucellosis-and-genetic-diversity-of-brucella-abortus-in-kazakhstan
#15
Elena Shevtsova, Alexandr Shevtsov, Kasim Mukanov, Maxim Filipenko, Dinara Kamalova, Igor Sytnik, Marat Syzdykov, Andrey Kuznetsov, Assel Akhmetova, Mira Zharova, Talgat Karibaev, Pavel Tarlykov, Erlan Ramanculov
Brucellosis is a major zoonotic infection in Kazakhstan. However, there is limited data on its incidence in humans and animals, and the genetic diversity of prevalent strains is virtually unstudied. Additionally, there is no detailed overview of Kazakhstan brucellosis control and eradication programs. Here, we analyzed brucellosis epidemiological data, and assessed the effectiveness of eradication strategies employed over the past 70 years to counteract this infection. We also conducted multiple loci variable-number tandem repeat analysis (MLVA) of Brucella abortus strains found in Kazakhstan...
2016: PloS One
https://www.readbyqxmd.com/read/27907050/when-is-the-brain-dead-living-like-electrophysiological-responses-and-photon-emissions-from-applications-of-neurotransmitters-in-fixed-post-mortem-human-brains
#16
Michael A Persinger, Nicolas Rouleau, Nirosha J Murugan, Lucas W E Tessaro, Justin N Costa
The structure of the post-mortem human brain can be preserved by immersing the organ within a fixative solution. Once the brain is perfused, cellular and histological features are maintained over extended periods of time. However, functions of the human brain are not assumed to be preserved beyond death and subsequent chemical fixation. Here we present a series of experiments which, together, refute this assumption. Instead, we suggest that chemical preservation of brain structure results in some retained functional capacity...
2016: PloS One
https://www.readbyqxmd.com/read/27906869/early-and-sustained-vasopressin-infusion-augments-the-hemodynamic-efficacy-of-restrictive-fluid-resuscitation-and-improves-survival-in-a-liver-laceration-model-of-hemorrhagic-shock
#17
Raúl J Gazmuri, Kasen Whitehouse, Kruti Shah, Karla Whittinghill, Alvin Baetiong, Jeejabai Radhakrishnan
BACKGROUND: Current management of hemorrhagic shock favors restrictive fluid resuscitation before control of the bleeding source. We investigated the additional effects of early and sustained vasopressin infusion in a swine model of hemorrhagic shock produced by liver laceration. METHODS: Forty male domestic pigs (32 to 40 kg) had a liver laceration inflicted with an X-shaped blade clamp, 32 received a second laceration at minute 7.5, and 24 received two additional lacerations at minute 15...
November 30, 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27906757/effect-of-an-immersive-preoperative-virtual-reality-experience-on-patient-reported-outcomes-a-randomized-controlled-trial
#18
Kimon Bekelis, Daniel Calnan, Nathan Simmons, Todd A MacKenzie, George Kakoulides
OBJECTIVE: To investigate the effect of exposure to a virtual reality (VR) environment preoperatively on patient-reported outcomes for surgical operations. BACKGROUND: There is a scarcity of well-developed quality improvement initiatives targeting patient satisfaction. METHODS: We performed a randomized controlled trial of patients undergoing cranial and spinal operations in a tertiary referral center. Patients underwent a 1:1 randomization to an immersive preoperative VR experience or standard preoperative experience stratified on type of operation...
November 30, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27906468/optimal-timing-of-hepatitis-c-treatment-for-patients-on-the-liver-transplant-waiting-list
#19
Jagpreet Chhatwal, Sumeyye Samur, Brian Kues, Turgay Ayer, Mark S Roberts, Fasiha Kanwal, Chin Hur, Drew Michael S Donnell, Raymond T Chung
: The availability of oral direct-acting antiviral (DAAs) has altered the hepatitis C virus (HCV) treatment paradigm for both pre- and post-liver transplant (LT) patients. There is a perceived trade-off between pre- versus post-LT treatment of HCV-treatment may improve liver function but potentially decrease the likelihood of a necessary LT. Our objective was to identify LT-eligible patients with decompensated cirrhosis who would benefit (and not benefit) from pre-LT treatment based on their MELD scores...
November 5, 2016: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/27906372/depth-based-refocusing-for-reducing-directional-aliasing-artifacts
#20
Ensun Lee, Seohee Yang, Miseon Han, Jeongtae Kim
We investigate a depth-based refocusing method using four-dimensional (4D) light field data, which can reduce directional aliasing artifacts in a refocused image. Unlike conventional filtering-based methods, the proposed method estimates the amount of aliasing artifacts using the disparity information between two neighboring views. It then applies an exact smoothing operation to the refocused image in order to remove the aliasing artifacts. By doing that, the proposed method is able to generate a smoothly blurred image in the out-of-focus region and a sharp image in the focused region...
November 28, 2016: Optics Express
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