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https://www.readbyqxmd.com/read/29668024/nutrition-considerations-after-nicu-discharge
#1
Taylor Peters, Cecelia Pompeii-Wolfe
Preterm infants are at high nutrition risk during neonatal intensive care and well after discharge. Nutrition care should be individualized and provided by a multidisciplinary team including a dietitian. Breast milk, the gold standard for feeding, may not meet the increased needs of preterm infants and may require fortification or supplementation. Decisions regarding formula choice and calorie concentration can also be challenging and require individualization based on growth, intake, and individual need. Developmental milestones should be considered during the initation of complementary food...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29667027/neonatal-overfeeding-impairs-differentiation-potential-of-mice-subcutaneous-adipose-mesenchymal-stem-cells
#2
Isabelle Dias, Ísis Salviano, André Mencalha, Simone Nunes de Carvalho, Alessandra Alves Thole, Laís Carvalho, Erika Cortez, Ana Carolina Stumbo
Nutritional changes in the development (intrauterine life and postnatal period) may trigger long-term pathophysiological complications such as obesity and cardiovascular disease. Metabolic programming leads to organs and tissues modifications, including adipose tissue, with increased lipogenesis, production of inflammatory cytokines, and decreased glucose uptake. However, stem cells participation in adipose tissue dysfunctions triggered by overfeeding during lactation has not been elucidated. Therefore, this study was the first to evaluate the effect of metabolic programming on adipose mesenchymal stem cells (ASC) from mice submitted to overfeeding during lactation, using the litter reduction model...
April 17, 2018: Stem Cell Reviews
https://www.readbyqxmd.com/read/29666098/a-misplaced-peripherally-inserted-central-catheter-presenting-as-contralateral-pleural-effusion
#3
Jogender Kumar, Sudeep K C, Kanya Mukhopadhyay, Somosri Ray
A preterm neonate born at 27 weeks, with a birth weight of 555 g, was on continuous positive airway pressure (CPAP) for apnoea of prematurity and initially received total parenteral nutrition (TPN) through the umbilical venous catheter. Peripherally inserted central catheter (PICC) was inserted in the left basilica vein on day 8 to continue TPN. The baby developed respiratory distress with persistent hypoxia after TPN was initiated through the PICC line. The baby required mechanical ventilation due to worsening of respiratory distress, and chest X-ray, as well as ultrasound conducted 12 hours, postinfusion of TPN revealed right-sided pleural effusion...
April 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29656488/importance-of-coverage-and-quality-for-impact-of-nutrition-interventions-delivered-through-an-existing-health-programme-in-bangladesh
#4
Phuong Hong Nguyen, Edward A Frongillo, Tina Sanghvi, Sunny S Kim, Silvia Alayon, Lan Mai Tran, Zeba Mahmud, Bachera Aktar, Purnima Menon
Understanding implementation of interventions is critical to illuminate if, how, and why the interventions achieve impact. Alive & Thrive integrated a nutrition intervention into an existing maternal, neonatal, and child health (MNCH) programme in Bangladesh, documenting improvements in women's micronutrient supplement intake and dietary diversity. Here, we examined how well the nutrition intervention was implemented and which elements of implementation explained intervention impact. Survey data were collected in 2015 and 2016 from frontline health workers (FLW) and households in areas randomized to nutrition-focused MNCH (intensified interpersonal counselling, community mobilization, distribution of free micronutrient supplements, and weight-gain monitoring) or standard MNCH (antenatal care with standard nutrition counselling)...
April 14, 2018: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29649108/postnatal-growth-disadvantage-of-the-small-for-gestational-age-preterm-twins
#5
Iris Morag, Orly Stern Levkovitz, Maya Siman-Tov, Mor Frisch, Orit Pinhas-Hamiel, Tzipi Strauss
In this study, we examined early growth characteristics among small-for-gestational-age (SGA) preterm twins compared to their appropriate-for-gestational-age (AGA) counterparts. A retrospective study evaluated all consecutive twins born between 2008 and 2015 at a tertiary referral center whose gestational age ranged from 30.0 to 34.86 weeks. Included were twins in which one twin was AGA and the other SGA at birth. Changes of ≥2, 1-1.99, and 0-0.99 in z-score between births and 36 weeks post menstrual age (PMA) were respectively defined as severe, moderate, and mild postnatal growth failure (PNGF) in weight or head circumference (HC)...
April 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29648999/cord-blood-klotho-levels-are-inversely-associated-with-leptin-in-healthy-latino-neonates-at-risk-for-obesity
#6
Janet M Wojcicki, Aric A Prather, Elissa Epel, Dan Wang, Dena B Dubal
BACKGROUND: Klotho serum levels reflect nutritional state in adults including obesity and anorexia. The relationship between cord blood klotho levels at birth and parameters of growth including anthropometrics are not known. METHODS: We evaluated the relationship between cord blood klotho, leptin and adipocyte hormones and infant, child and maternal anthropometrics and maternal depression in a cohort of 73 children. Non-parametric tests were used to assess differences between dichotomous and categorical predictors and klotho levels and Spearman's rank coefficients were used to assess the relationship between klotho levels and continuous predictors...
April 12, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29630025/direct-percutaneous-endoscopic-jejunostomy-for-the-management-of-gastroparesis-in-pregnancy
#7
Sawan Vijay Rupani, William F Ergen, Frederick Weber, Shajan Peter
BACKGROUND: Providing meaningful nutrition in cases of refractory hyperemesis during pregnancy can be challenging; although intragastric enteral nutrition is the most common approach, it is contraindicated in certain cases and carries the risk of increased nausea and vomiting. CASE: A 36-year-old primigravid woman with a history of gastroparesis presented at 16 weeks of gestation with nausea and vomiting. With no improvement with conventional approaches and signs of malnutrition, a direct percutaneous endoscopic jejunostomy was placed...
April 6, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29628208/complex-gastroschisis-clinical-spectrum-and-neonatal-outcomes-at-a-referral-center
#8
Pablo Laje, Maria V Fraga, William H Peranteau, Holly L Hedrick, Nahla Khalek, Juliana S Gebb, Julie S Moldenhauer, Mark P Johnson, Alan W Flake, N Scott Adzick
AIM OF THE STUDY: To evaluate the outcomes of neonates with complex gastroschisis (GC), and correlate outcomes with each type of complication. METHODS: Retrospective review of patients with complex GC owing to prenatal and/or postnatal abdominal complications; 2008-2016. Primary outcomes: time to discontinue parenteral nutrition (off-PN), length of stay (LOS) and neonatal survival. MAIN RESULTS: We treated 58 patients with complex gastroschisis owing to abdominal complications, which were: intestinal necrosis at birth (n=9), intestinal atresia (n=16), medical necrotizing enterocolitis (NEC) (n=15), surgical NEC (n=1), in utero volvulus (n=1), vanishing gastroschisis (n=2), severe intestinal dysmotility (n=1), delayed abdominal closure (n=3), abdominal compartment syndrome (n=2) and hiatal hernia/severe gastroesophageal reflux disease (GERD; n=11)...
March 14, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29621406/is-a-vegetarian-diet-safe-to-follow-during-pregnancy-a-systematic-review-and-meta-analysis-of-observational-studies
#9
Chang Tan, Yudi Zhao, Suqing Wang
BACKGROUND: Whether a vegetarian diet is appropriate for pregnancy remains unclear. OBJECTIVE: This study aimed to determine the association between vegetarian diet during pregnancy and various maternal-fetal outcomes. METHOD: PubMed-Medline, EMBASE, and Cochrane Library databases were searched for relevant articles published by August 30, 2017. Quantitative data were analyzed by a random-effects model with pooled odds ratios or weighted mean difference (WMD) and 95% confidence interval as aggregate estimations...
April 5, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29621287/weather-and-landscape-factors-affect-white-tailed-deer-neonate-survival-at-ecologically-important-life-stages-in-the-northern-great-plains
#10
Eric S Michel, Jonathan A Jenks, Kyle D Kaskie, Robert W Klaver, William F Jensen
Offspring survival is generally more variable than adult survival and may limit population growth. Although white-tailed deer neonate survival has been intensively investigated, recent work has emphasized how specific cover types influence neonate survival at local scales (single study area). These localized investigations have often led to inconsistences within the literature. Developing specific hypotheses describing the relationships among environmental, habitat, and landscape factors influencing white-tailed deer neonate survival at regional scales may allow for detection of generalized patterns...
2018: PloS One
https://www.readbyqxmd.com/read/29615158/reduction-in-central-line-associated-bloodstream-infections-in-a-nicu-practical-lessons-for-its-achievement-and-sustainability
#11
Judith A Hawes, Kyong-Soon Lee
Central venous catheters are commonly used for the provision of parenteral nutrition and medications for critically ill neonates in the NICU. However, central line-associated bloodstream infections (CLABSIs) are a major complication associated with their use and remain an important cause of nosocomial sepsis in NICUs. Central line-associated bloodstream infection has shifted from being an expected routine complication of central line use to an adverse event now evaluated as a critical event with the goal of identifying root causes so future CLABSI events are prevented...
March 1, 2018: Neonatal Network: NN
https://www.readbyqxmd.com/read/29607030/timing-of-precipitation-in-an-arid-environment-effects-on-population-performance-of-a-large-herbivore
#12
Levi J Heffelfinger, Kelley M Stewart, Anthony P Bush, James S Sedinger, Neal W Darby, Vernon C Bleich
Climate models predict that shifts in temperature and precipitation patterns are likely to occur across the globe. Changing climate will likely have strong effects on arid environments as a result of increased temperatures, increasing frequency and intensity of droughts, and less consistent pulses of rainfall. Therefore, understanding the link between patterns of precipitation, temperature, and population performance of species occupying these environments will continue to increase in importance as climatic shifts occur within these natural ecosystems...
March 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29606021/wastage-of-standardised-parenteral-nutrition-solution-a-challenge-for-neonatal-units
#13
Mangesh Deshmukh, Jessica Grzejszczyk, Shailender Mehta, Sanjay Patole
BACKGROUND: Standardised parental nutrition (PN) has been used in many neonatal intensive care unit (NICU). Easy accessibility, better provision of nutrients, reduced prescription errors and cost savings are some of its benefits. Fixed large volume (e.g. 750-1000 mL) and short expiry limit (48 hrs) along with changing metabolic needs of neonates leads to significant wastage of PN solution. OBJECTIVE: To evaluate wastage of PN solution in our 22-bedded NICU. METHODS: The audit was conducted over 21-month period (July 2015-April 2017)...
April 1, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29603266/source-and-quality-of-enteral-nutrition-influences-oxidative-stress-in-preterm-infants-a-prospective-cohort-study
#14
Gerhard Fusch, Souvik Mitra, Heinrich Topp, Arnav Agarwal, So Hon Yiu, Josefin Bruhs, Niels Rochow, Anja Lange, Matthias Heckmann, Christoph Fusch
BACKGROUND: Preterm infants are at risk of oxidative stress from neonatal intensive care interventions. 8-Oxo-2'-deoxyguanosine (8-oxodG), generated by oxygen radical attack on DNA, is a potential marker of oxidative stress. The aim of the present study was to investigate the impact of quality and source of enteral nutrition (EN) on renal excretion of 8-oxodG in preterm infants. METHODS: Spontaneous urine samples were collected on postnatal days 26-31 in 33 preterm infants...
March 30, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29602551/relationship-between-perioperative-blood-transfusion-and-surgical-site-infections-in-pediatric-general-and-thoracic-surgical-patients
#15
Jason Fawley, Thomas H Chelius, Marjorie J Arca
BACKGROUND: Recently, perioperative transfusions were demonstrated to be associated with higher rate of surgical site infections (SSIs) in neonates. We sought to examine whether a similar relationship exists between perioperative blood transfusions and SSI among non-neonatal pediatric general surgical patients. METHODS: We conducted an IRB-approved retrospective study reviewing non-neonatal patients (age greater than 28days and less than 18years) who underwent a general or thoracic surgical procedure in 2012, 2013, 2014, in the American College of Surgeons National Safety and Quality Improvement Project-Pediatric (ACS-NSQIP-P) Participant User Files...
March 4, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29602257/neonatal-oesophageal-perforation-the-role-for-non-operative-management
#16
Kate Hodgson, Andrea Togo, Aideen M Moore, Amanda Moody, Sebastian K King, Augusto Zani
AIM: Isolated oesophageal perforation in neonates is a rare but potentially life-threatening condition. Although management has historically been operative, conservative management (antibiotics, bowel rest, parenteral nutrition) is now more routinely used. The aim of this study was to evaluate the management of this condition in two large neonatal surgical centres. METHODS: A retrospective cohort study was conducted for neonates admitted to The Hospital for Sick Children (Toronto, Canada) or The Royal Children's Hospital (Melbourne, Australia) with a diagnosis of oesophageal perforation, from 2006 to 2016...
March 30, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29601596/an-anthropometric-approach-to-characterising-neonatal-morbidity-and-body-composition-using-air-displacement-plethysmography-as-a-criterion-method
#17
Jacqueline Huvanandana, Angela E Carberry, Robin M Turner, Emily J Bek, Camille H Raynes-Greenow, Alistair L McEwan, Heather E Jeffery
BACKGROUND: With the greatest burden of infant undernutrition and morbidity in low and middle income countries (LMICs), there is a need for suitable approaches to monitor infants in a simple, low-cost and effective manner. Anthropometry continues to play a major role in characterising growth and nutritional status. METHODS: We developed a range of models to aid in identifying neonates at risk of malnutrition. We first adopted a logistic regression approach to screen for a composite neonatal morbidity, low and high body fat (BF%) infants...
2018: PloS One
https://www.readbyqxmd.com/read/29601436/gavage-feed-volume-determines-the-gastric-emptying-rate-in-preterm-infants
#18
Cristina H F Ferreira, Francisco E Martinez, Gerson C Crott, Jaques Belik
OBJECTIVE: Feeding intolerance, manifesting as increased gastric residual, is a common finding in preterm neonates. Little is known about the regulation of gastric emptying early in life and the extent to which this plays a role in the preterm infants' feeding tolerance. The goal of this study was to evaluate clinically stable 28- to 32-week gestation neonates during the first 4 weeks of life and noninvasively determine their gastric emptying rate. STUDY DESIGN: Ultrasound measurements of gastric milk content volume were obtained from 25 neonates immediately after, 30 and/or 60 minutes following routine gavage feeds...
March 29, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29599768/mother-s-milk-a-purposeful-contribution-to-the-development-of-the-infant-microbiota-and-immunity
#19
REVIEW
Kirsty Le Doare, Beth Holder, Aisha Bassett, Pia S Pannaraj
Breast milk is the perfect nutrition for infants, a result of millions of years of evolution. In addition to providing a source of nutrition, breast milk contains a diverse array of microbiota and myriad biologically active components that are thought to guide the infant's developing mucosal immune system. It is believed that bacteria from the mother's intestine may translocate to breast milk and dynamically transfer to the infant. Such interplay between mother and her infant is a key to establishing a healthy infant intestinal microbiome...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29594085/stress-signals-during-sucking-activity-are-associated-with-longer-transition-time-to-full-oral-feeding-in-premature-infants
#20
You Gyoung Yi, Byung-Mo Oh, Seung Han Shin, Jin Yong Shin, Ee-Kyung Kim, Hyung-Ik Shin
Several treatments have been proposed to shorten the time to the attainment of full oral feeding (FOF) for premature infants, but there are only a few evaluation methods useful in estimating predictors of this period. We investigated whether specific items within the disorganized sucking patterns described by the Neonatal Oral-Motor Assessment Scale (NOMAS) could estimate the time to FOF in preterm infants with feeding difficulty. Preterm infants diagnosed with a disorganized sucking pattern in the NOMAS evaluation before 50 weeks of postmenstrual age were included...
2018: Frontiers in Pediatrics
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