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https://www.readbyqxmd.com/read/29231765/imaging-corticotropin-releasing-factor-and-nociceptin-in-addiction-and-ptsd-models
#1
Savannah Tollefson, Michael Himes, Rajesh Narendran
Addiction is composed of three phases: intoxication, withdrawal, and craving. Negative reinforcement, strengthening a behaviour by removing an aversive stimulus, has been associated with the withdrawal phase. An imbalance of neurotransmitters within the brain's stress (nociceptin, neuropeptide Y) and anti-stress (CRF, norepinephrine, etc.) system is attributed to negatively reinforced compulsive behaviours associated with relapse. Similarly, post-traumatic stress disorder is characterized by an overactive stress system...
December 12, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/29230526/peripheral-nerve-diffusion-tensor-imaging-dti-normal-values-and-demographic-determinants-in-a-cohort-of-60-healthy-individuals
#2
Moritz Kronlage, Véronique Schwehr, Daniel Schwarz, Tim Godel, Lorenz Uhlmann, Sabine Heiland, Martin Bendszus, Philipp Bäumer
OBJECTIVE: To identify demographic determinants of peripheral nerve diffusion tensor imaging (DTI) and to establish normal values for fractional anisotropy (FA), axial diffusivity (AD), radial diffusivity (RD), and mean diffusivity (MD). METHODS: Sixty subjects were examined at 3 Tesla by single-shot DTI. FA, AD, RD, and MD were collected for the sciatic, tibial, median, ulnar, and radial nerve and were correlated with demographic variables. RESULTS: Mean FA of all nerves declined with increasing age (r = -0...
December 11, 2017: European Radiology
https://www.readbyqxmd.com/read/29228344/relationship-between-inter-rectus-distance-and-symptom-severity-in-women-with-diastasis-recti-in-the-early-postpartum-period
#3
Nadia Keshwani, Sunita Mathur, Linda McLean
Background: Diastasis recti abdominis (DrA) is associated with negative body image, musculoskeletal pain and dysfunction, and perhaps urogynecological complaints. The severity of DrA has traditionally been determined by measuring the inter-rectus distance (IRD); however, the relationship between IRD and symptoms in women with DrA is unclear. Objective: The objective of the study was to investigate the relationship between IRD and symptom severity in women with DrA in the early postpartum period...
December 4, 2017: Physical Therapy
https://www.readbyqxmd.com/read/29227723/interventions-to-address-sexual-problems-in-people-with-cancer-american-society-of-clinical-oncology-clinical-practice-guideline-adaptation-of-cancer-care-ontario-guideline
#4
Jeanne Carter, Christina Lacchetti, Barbara L Andersen, Debra L Barton, Sage Bolte, Shari Damast, Michael A Diefenbach, Katherine DuHamel, Judith Florendo, Patricia A Ganz, Shari Goldfarb, Sigrun Hallmeyer, David M Kushner, Julia H Rowland
Purpose The adaptation of the Cancer Care Ontario (CCO) guideline Interventions to Address Sexual Problems in People With Cancer provides recommendations to manage sexual function adverse effects that occur as a result of cancer diagnosis and/or treatment. Methods ASCO staff reviewed the guideline for developmental rigor and updated the literature search. An ASCO Expert Panel ( Table A1 ) was assembled to review the guideline content and recommendations. Results The ASCO Expert Panel determined that the recommendations from the 2016 CCO guideline are clear, thorough, and based upon the most relevant scientific evidence...
December 11, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29227407/a-three-dimensional-anthropometric-evaluation-of-facial-morphology
#5
Ahmet Arif Celebi, Chung How Kau, Felice Femiano, Ludovica Bucci, Letizia Perillo
OBJECTIVES: The aims of this study were to evaluate sexual dimorphism for facial features within Italian and Egyptian populations and to compare the facial morphology by sex between these 2 populations. MATERIALS AND METHODS: Three-dimensional (3D) facial images were acquired by using the portable 3dMDface System, which captured 259 subjects from 2 population groups of Italian (n = 139) and Egyptian (n = 120). Each population was categorized into male and female groups for evaluation...
December 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29227227/reward-system-activation-in-response-to-alcohol-advertisements-predicts-college-drinking
#6
Andrea L Courtney, Kristina M Rapuano, James D Sargent, Todd F Heatherton, William M Kelley
OBJECTIVE: In this study, we assess whether activation of the brain's reward system in response to alcohol advertisements is associated with college drinking. Previous research has established a relationship between exposure to alcohol marketing and underage drinking. Within other appetitive domains, the relationship between cue exposure and behavioral enactment is known to rely on activation of the brain's reward system. However, the relationship between neural activation to alcohol advertisements and alcohol consumption has not been studied in a nondisordered population...
January 2018: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/29226864/cardiorespiratory-fitness-and-white-matter-neuronal-fiber-integrity-in-mild-cognitive-impairment
#7
Kan Ding, Takashi Tarumi, David C Zhu, Benjamin Tseng, Binu P Thomas, Marcel Turner, Justin Repshas, Diana R Kerwin, Kyle B Womack, Hanzhang Lu, C Munro Cullum, Rong Zhang
BACKGROUND: Mounting evidence showed the self-reported levels of physical activity are positively associated with white matter (WM) integrity and cognitive performance in normal adults and patients with mild cognitive impairment (MCI). However, the objective measure of cardiorespiratory fitness (CRF) was not used in these studies. OBJECTIVE: To determine the associations of CRF measured by maximal oxygen uptake (VO2max) with WM fiber integrity and neurocognitive performance in older adults with MCI...
December 6, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29226735/social-media-for-health-promotion-what-messages-are-women-receiving-about-cardiovascular-disease-risk-by-the-canadian-heart-and-stroke-foundation
#8
Christine A Gonsalves, Kerry R McGannon, Robert J Schinke
The aim of this study was to explore the meanings of women's cardiovascular disease constructed within the Canadian Heart and Stroke Foundation Facebook page. Posts from Heart and Stroke Foundation and public user comments surrounding the launch of the Heart and Stroke Foundation re-branding were of interest. Ethnographic content analysis was employed to analyse text ( n = 40), images ( n = 32), videos ( n = 6), user comments and replies ( n = 42) from November 2016 to March 2017. Constructions (re)presented on Facebook of 'typical' women at risk and risk reduction were problematic as women most at risk were excluded through the use of consumerist, medicalized identities which also excluded promotion of healthy behaviour changes...
November 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/29226548/diffusion-tensor-imaging-determines-three-dimensional-architecture-of-human-cervix-a-cross-sectional-study
#9
J P Nott, E Pervolaraki, A P Benson, E A Bonney, J D Pickering, N Wilkinson, Nab Simpson
OBJECTIVE: To determine the microarchitecture of the cervix using high-resolution diffusion tensor (DT) magnetic resonance imaging (MRI). DESIGN: Cross-sectional study. SETTING: Leeds, UK. SAMPLE: Women undergoing hysterectomy for benign pathology. METHODS: Ex-vivo DT-MRI measurements were obtained using a 9.4-T Bruker nuclear magnetic resonance (NMR) spectrometer on seven fixed human cervices obtained at hysterectomy...
October 26, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29225720/new-frontiers-in-molecular-and-imaging-research-on-evaluation-and-diagnosis-of-bladder-outlet-obstruction-in-women
#10
Laura Martinez, Rose Khavari
Purpose: Diagnosis of bladder outlet obstruction (BOO) often presents a challenge in female patients. Traditional diagnostic elements such as symptom history and urodynamic data are rarely clear cut in women. Therefore, we sought to review the current literature on diagnosis of female BOO, focusing on new frontiers in the realm of molecular markers and imaging modalities. Recent Findings: In addition to fluoroscopy in the setting of videourodynamics, ultrasound and MRI can augment the diagnosis and aid in therapeutic planning in certain etiologies of female BOO...
December 2017: Current Bladder Dysfunction Reports
https://www.readbyqxmd.com/read/29225071/clinical-characteristics-of-pulmonary-mycobacterium-lentiflavum-disease-in-adult-patients
#11
Kazuma Yagi, Kozo Morimoto, Makoto Ishii, Ho Namkoong, Satoshi Okamori, Takanori Asakura, Shoji Suzuki, Takahiro Asami, Yoshifumi Uwamino, Yohei Funatsu, Hiroshi Fujiwara, Hirofumi Kamata, Tomoyasu Nishimura, Tomoko Betsuyaku, Atsuyuki Kurashima, Naoki Hasegawa
BACKGROUND: Mycobacterium lentiflavum organisms are slow-growing nontuberculous mycobacteria often associated with immunocompromised state and cervical lymphadenitis in young children. However, little is known about the clinical importance of pulmonary infection with M. lentiflavum in adults. METHODS: We reviewed the medical records of all adults who met the diagnostic criteria of pulmonary M. lentiflavum disease at Keio University Hospital and Fukujuji Hospital from 2001 to 2015...
December 7, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29224740/chest-pain-and-mental-stress-induced-myocardial-ischemia-sex-differences
#12
Pratik Pimple, Muhammad Hammadah, Kobina Wilmot, Ronnie Ramadan, Ibhar Al Mheid, Oleksiy Levantsevych, Samaah Sullivan, Ernest V Garcia, Jonathon Nye, Amit J Shah, Laura Ward, Puja Mehta, Paolo Raggi, J Douglas Bremner, Arshed A Quyyumi, Viola Vaccarino
BACKGROUND: Mental stress-induced myocardial ischemia (MSIMI) is a frequent phenomenon in patients with coronary artery disease. Women with coronary artery disease tend to have more MSIMI and more chest pain/anginal symptoms than men, but whether the association between MSIMI and angina burden differs in women and men, is unknown. METHODS: This was a cross-sectional study with experimental manipulation of 950 individuals with stable coronary artery disease. Chest pain/angina frequency in the previous 4 weeks was assessed with the Seattle Angina Questionnaire's angina-frequency subscale...
December 7, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/29224088/sex-differences-in-body-composition
#13
Miriam A Bredella
Body composition differs between men and women. Men have more lean mass, and women have more fat mass than men. Men are more likely to accumulate adipose tissue around the trunk and abdomen, whereas women usually accumulate adipose tissue around the hips and thighs. Less is known about sex differences in ectopic fat depots. Advances in imaging allow the noninvasive assessment of abdominal and femorogluteal fat compartments, intramyocellular lipids, intrahepatic lipids, pericardial adipose tissue, and neck adipose tissue including brown adipose tissue and tongue adipose tissue...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29223020/depressive-symptoms-impaired-glucose-metabolism-high-visceral-fat-and-high-systolic-blood-pressure-in-a-subgroup-of-women-with-recent-gestational-diabetes
#14
U Ferrari, F Banning, I Freibothe, K Tröndle, V Sacco, C Wichmann, S Reif, S Moschko, A Potzel, C Gar, N N Sommer, D Popp, J Seissler, A Lechner, H Künzel
Women with gestational diabetes (GDM) are a high risk group for early type 2 diabetes (T2D). Depression is a risk factor for T2D in the general population. We investigated in women after a recent pregnancy with GDM and without a clinical diagnosis of depression, whether mild to moderate depressive symptoms associate with pathologic glucose metabolism. In a cross-sectional analysis, we examined 173 women, 9 ± 3 months after delivery with several psychopathological assessments, 5-point oral glucose tolerance test with insulin, anthropometrics, and laboratory chemistry...
December 5, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29222861/zero-fluoroscopy-permanent-pacemaker-implantation-using-ensite-navx-system-clinical-viability-or-fanciful-technique
#15
Ping Guo, Jie Qiu, Yan Wang, Guangzhi Chen, Riccardo Proietti, Al-Selmi Fadhle, Chunxia Zhao, Dao Wen Wang
BACKGROUND: Fluoroscopy is the imaging modality routinely used for cardiac device implantation and electrophysiological procedures. Due to the rising concern regarding the harmful effects of radiation exposure to both the patients and operation staffs, novel 3D mapping systems have been developed and implemented in electrophysiological procedure for the navigation of catheters inside the heart chambers. Their applicability in cardiac device implantation has been rarely reported. Our aim is to evaluate the feasibility and safety of permanent pacemaker implantation without fluoroscopy...
December 9, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29221944/living-uterus-donation-and-transplantation-experience-of-interest-and-screening-in-a-single-center-in-the-united-states
#16
Liza Johannesson, Kristin Wallis, E Colin Koon, Gregory J Mckenna, Tiffany Anthony, Sara G Leffingwell, Goran B Klintmalm, Robert T Gunby, Giuliano Testa
BACKGROUND: Little is known about attitudes toward uterus donation and transplantation in society and the interest of the women the treatment is aimed to assist. OBJECTIVE: This study examined the interest of recipients and living donors in our uterus transplantation program; it describes the screening protocol we developed and the results of the screening and reports demographic data and characteristics of screened candidates. STUDY DESIGN: Initial screening and evaluation included physical examinations by a gynecologist and a transplant surgeon; psychological evaluation; imaging (x-ray, computed tomography, ultrasound); blood tests; immunological testing; viral, bacterial, and fungal testing; drug screen; hormonal testing; Pap smear; urinalysis; and electrocardiogram...
December 5, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29221936/volumetric-measurement-of-hepatic-tumors-accuracy-of-manual-contouring-using-ct-with-volumetric-pathology-as-the-reference-method
#17
L F Pupulim, M Ronot, V Paradis, S Chemouny, V Vilgrain
PURPOSE: The purpose of this study was to assess the accuracy of liver tumor volumetry by manual contouring on computed tomography (CT) compared to pathological tumor volume determined from surgical specimen that served as a reference method. PATIENTS AND METHOD: Thirty-eight patients with planned liver surgery and a total of 41 liver tumors were included. There were 24 men and 14 women (mean age: 57 years; range: 32-85 years). Two readers calculated tumor volume by manual contouring on axial CT images...
December 5, 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/29221270/analysis-of-the-clinical-differentiation-of-pulmonary-sclerosing-pneumocytoma-and-lung-cancer
#18
Jun Zhu
Background: Pulmonary sclerosing pneumocytoma (PSP) is a rare benign lung tumor. This study investigated the diagnostic experience of PSP and lung cancer. Methods: This study is a retrospective study. We observed the locations of lung lesions, imaging form and clinical symptoms, and recorded the surgical complications through comparing patients with PSP and lung cancer. Results: From December 2012 to February 2017, 187 PSP cases and 197 lung cancer cases were collected...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29220731/quantitative-texture-analysis-in-the-prediction-of-idh-status-in-low-grade-gliomas
#19
Asgeir Store Jakola, Yi-Hua Zhang, Anne J Skjulsvik, Ole Solheim, Hans Kristian Bø, Erik Magnus Berntsen, Ingerid Reinertsen, Sasha Gulati, Petter Förander, Torkel B Brismar
OBJECTIVES: Molecular markers provide valuable information about treatment response and prognosis in patients with low-grade gliomas (LGG). In order to make this important information available prior to surgery the aim of this study was to explore if molecular status in LGG can be discriminated by preoperative magnetic resonance imaging (MRI). PATIENTS AND METHODS: All patients with histopathologically confirmed LGG with available molecular status who had undergone a preoperative standard clinical MRI protocol using a 3T Siemens Skyra scanner during 2008-2015 were retrospectively identified...
December 5, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29220579/pupillary-responses-to-static-images-of-men-and-women-a-possible-measure-of-sexual-interest
#20
Robert J Snowden, Aimee McKinnon, Julie Fitoussi, Nicola S Gray
The pupil dilates to images that are arousing. In Experiment 1, we examined if the pupil's response to brief presentations (2,000 ms) of static images could be used to identify individuals' sexual orientation. Participants were grouped according to their self-reported gender and sexual orientation (male heterosexual, N = 20; male bisexual, N = 13; male homosexual, N = 19; female heterosexual, N = 28; female bisexual, N = 21; female homosexual, N = 17). Pupil size was monitored to images of men in seminude poses, women in seminude poses, or neutral images...
December 8, 2017: Journal of Sex Research
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