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Ligament cruciate anterior

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https://www.readbyqxmd.com/read/29031199/artesunate-attenuates-aclt-induced-osteoarthritis-by-suppressing-osteoclastogenesis-and-aberrant-angiogenesis
#1
Chengjin Zhao, Qingbai Liu, Kunzheng Wang
Artesunate (ART) is a semi-synthetic derivative of artemisinin and used preferentially in treatment of malaria in China. ART has strong anti-inflammatory, anti-tumor, and anti-angiogenic properties. Although the pharmacological effect of ART in osteoarthritis (OA) is unknown, evidence suggests that ART might regulate osteoclastogenesis through NF-κB signaling. In this study we explored the therapeutic effect of ART in an anterior cruciate ligament transection (ACLT)-induced OA model. We found that ART effectively relieved ACLT-induced osteoarthritis, as demonstrated by the improvement expression of pathological genes...
October 11, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29028449/geometric-characteristics-of-the-knee-are-associated-with-a-noncontact-acl-injury-to-the-contralateral-knee-after-unilateral-acl-injury-in-young-female-athletes
#2
James G Levins, Erin C Argentieri, Daniel R Sturnick, Mack Gardner-Morse, Pamela M Vacek, Timothy W Tourville, Robert J Johnson, James R Slauterbeck, Bruce D Beynnon
BACKGROUND: Contralateral anterior cruciate ligament (CACL) injury after recovery from a first-time ACL rupture occurs at a high rate in young females; however, little is known about the risk factors associated with bilateral ACL trauma. HYPOTHESIS: The geometric characteristics of the contralateral knee at the time of the initial ACL injury are associated with risk of suffering a CACL injury in these female athletes. STUDY DESIGN: Case-control study; Level of evidence, 3...
October 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29028445/return-to-sport-specific-performance-after-primary-anterior-cruciate-ligament-reconstruction-a-systematic-review
#3
Nicholas G Mohtadi, Denise S Chan
BACKGROUND: Physicians counseling athletes on the prognosis of sport-specific performance outcomes after anterior cruciate ligament reconstruction (ACLR) depend on the published literature. However, critical appraisal of the validity and biases in these studies is required to understand how ACLR affects an athlete's ability to return to sport, the athlete's sport-specific performance, and his or her ability to achieve preinjury levels of performance. PURPOSE: This review identifies the published prognostic studies evaluating sport-specific performance outcomes after ACLR...
October 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29028358/posterior-tibial-translation-measurements-on-magnetic-resonance-imaging-improve-diagnostic-sensitivity-for-chronic-posterior-cruciate-ligament-injuries-and-graft-tears
#4
Nicholas N DePhillipo, Mark E Cinque, Jonathan A Godin, Gilbert Moatshe, Jorge Chahla, Robert F LaPrade
BACKGROUND: Magnetic resonance imaging (MRI) of the knee is a highly sensitive and specific method for diagnosing acute posterior cruciate ligament (PCL) tears, with a reported accuracy of 96% to 100%. In chronic and revision settings, these injuries may be missed on MRI because of the apparent continuity of nonfunctional PCL fibers. Posterior tibial translation (PTT) of the medial compartment has been identified as a potential secondary finding of PCL tear on routine MRI. Purpose/Hypothesis: The purpose of this study was to evaluate the sensitivity of PTT on MRI associated with PCL injuries and compare it with the sensitivity of a radiologist's MRI interpretation with preoperative posterior knee stress radiographs as the gold standard...
October 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29026421/comparison-of-patellar-versus-hamstring-tendon-autografts-in-arthroscopic-anterior-cruciate-ligament-reconstruction-a-6-month-follow-up-of-a-randomized-clinical-trial
#5
Alireza Sadeghpour, Adel Ebrahimpour, Bahamin Attar, Zahra Azizian
BACKGROUND: The purpose of this study was to compare the outcomes of anterior cruciate ligament (ACL) reconstruction using the patellar versus hamstring tendon (HT) autograft. MATERIALS AND METHODS: In this randomized clinical trial, fifty patients undergoing arthroscopic ACL reconstruction were randomized into two equal groups: Those treated with either autogenous patellar tendon grafts (PT group) or HT group grafts. All patients were reviewed immediately after surgery, at 6 and 12 weeks after surgery, and then at 6 months using the International Knee Documentation Committee evaluation form...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29024605/hip-and-ankle-kinematics-in-noncontact-anterior-cruciate-ligament-injury-situations-video-analysis-using-model-based-image-matching
#6
Hideyuki Koga, Atsuo Nakamae, Yosuke Shima, Roald Bahr, Tron Krosshaug
BACKGROUND: Detailed kinematic descriptions of real anterior cruciate ligament (ACL) injury situations are limited to the knee only. PURPOSE: To describe hip and ankle kinematics as well as foot position relative to the center of mass (COM) in ACL injury situations through use of a model-based image-matching (MBIM) technique. The distance between the projection of the COM on the ground and the base of support (BOS) (COM_BOS) normalized to the femur length was also evaluated...
October 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29023273/return-to-sports-after-athletes-undergo-meniscal-surgery-a-systematic-review
#7
Yong Seuk Lee, O-Sung Lee, Seung Hoon Lee
OBJECTIVE: The aim of this systematic review was to determine the time to and rate of the return to sports (RTS) after meniscal surgery and to compare these values among the different types of meniscal surgeries. STUDY DESIGN: Systematic review. METHODS: The MEDLINE, EMBASE, and Cochrane databases were searched. Studies that met the following criteria were included: (1) English article, (2) full-text available, (3) study on athletes, and (4) primary outcome is RTS after meniscal surgery, such as meniscectomy, meniscal repair, and meniscal allograft transplantation (MAT)...
October 5, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29020716/improving-joint-pain-and-function-in-osteoarthritis
#8
Claire Owens, Philip G Conaghan
Osteoarthritis has become a major chronic pain condition. It affects more than 10% of adults and accounts for almost 10% of health service resources. The impact of osteoarthritis is amplified by underuse of effective muscle strengthening exercises and a focus on often less effective and poorly tolerated analgesic therapies. Although traditionally considered to be primarily a disease of cartilage, there is now ample evidence that typical clinical osteoarthritis involves multiple tissue pathologies. Increased BMI is associated with a higher incidence of knee osteoarthritis...
December 2016: Practitioner
https://www.readbyqxmd.com/read/29019442/the-use-of-hamstring-fatigue-to-reduce-quadriceps-inhibition-after-anterior-cruciate-ligament-reconstruction
#9
Timothy Lowe, Xuanliang Neil Dong
Arthrogenic muscle inhibition, an inability to fully activate the quadriceps muscles, has been persistently observed after anterior cruciate ligament reconstruction (ACLr) surgery. Reductions in quadriceps activation may be partly due to the flexion reflex pathway, hamstrings activation, and reciprocal quadriceps inhibition. Since central fatigue has been shown to modify hamstring excitability and change the hamstring reflex response, hamstring fatigue might alleviate quadriceps muscle inhibition by counteracting the flexion reflex...
January 1, 2017: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/29016234/limited-evidence-suggests-a-protective-association-between-oral-contraceptive-pill-use-and-anterior-cruciate-ligament-injuries-in-females-a-systematic-review
#10
Kathleen Samuelson, Ethan M Balk, Erika L Sevetson, Braden C Fleming
CONTEXT: Female athletes aged 14 to 18 years are at particular risk for anterior cruciate ligament (ACL) injuries. Hormonal factors are thought to predispose them to this injury. Oral contraceptive pills (OCPs) might reduce ACL injury risk, although the literature appears controversial. OBJECTIVE: To evaluate the association between OCP use and ACL injuries in women. The secondary objective was to determine the rates of ACL injuries in the pre- and postovulatory phases of the menstrual cycle in OCP and non-OCP (NOCP) users...
October 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28992997/association-of-tibial-plateau-fracture-morphology-with-ligament-disruption-in-the-context-of-multiligament-knee-injury
#11
REVIEW
Jack Porrino, Michael L Richardson, Keegan Hovis, Bruce Twaddle, Albert Gee
BACKGROUND: We identified common morphologies of tibial plateau fractures that arise with multiligament knee injuries (MLKIs), and investigated the relationship of the fracture with ligament tears. We also evaluated the correlation of 3 tibial plateau fracture classification systems (Schatzker, AO, and Duparc). METHODS: Over a 2-year period, a single orthopaedic surgeon at our institution managed 90 MLKIs. Images of those knees with a tibial plateau fracture were retrospectively reviewed and classified per Schatzker, AO, and Duparc systems...
September 12, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28992770/influence-of-demographic-and-utilization-of-physical-therapy-interventions-on-clinical-outcomes-and-revision-rates-following-anterior-cruciate-ligament-reconstruction
#12
Caitlin J Miller, Jesse C Christensen, Ryan D Burns
Study Design Retrospective cohort from Intermountain Healthcare system Jan 2007-Dec 2014. Background Recent evolutions in healthcare delivery are putting physical therapists in the forefront to be more responsible for providing high-quality rehabilitation care within a more cost-effective manner. Studies investigating the association between physical therapy (PT) visit utilization and outcomes in vulnerable patient populations following anterior cruciate ligament reconstruction (ACLR) may provide useful insights...
October 9, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28991041/quadriceps-function-and-knee-joint-ultrasonography-following-acl-reconstruction
#13
Derek N Pamukoff, Melissa M Montgomery, Tyler J Moffit, Michael N Vakula
PURPOSE: Individuals with anterior cruciate ligament reconstruction (ACLR) are at greater risk for knee osteoarthritis (OA), partially due to chronic quadriceps dysfunction. Articular cartilage is commonly assessed using magnetic resonance imaging and radiography, but these methods are expensive and lack portability. Ultrasound imaging may provide a cost-effective and portable alternative for imaging the femoral cartilage. The purpose of this study was to compare ultrasonography of the femoral cartilage between the injured and uninjured limbs of individuals with unilateral ACLR, and to examine the association between quadriceps function and ultrasonographic measures of femoral cartilage...
October 3, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28990574/an-evidence-based-evaluation-on-the-use-of-platelet-rich-plasma-in-orthopedics-a-review-of-the-literature
#14
Nasir Hussain, Herman Johal, Mohit Bhandari
Within orthopedics, the use of platelet-rich plasma (PRP) has been rapidly increasing in popularity, however, its true effectiveness has yet to be fully established. Several studies find that injecting PRP to the site of injury does not provide any significant benefit with respect to clinical outcomes; however, many others report the contrary. Due to the conflicting evidence and multiple meta-analyses conducted on the topic, a literature review of high-quality evidence on the use of PRP for common orthopaedic conditions was performed...
2017: SICOT-J
https://www.readbyqxmd.com/read/28990491/young-athletes-after-anterior-cruciate-ligament-reconstruction-cleared-for-sports-participation-how-many-actually-meet-recommended-return-to-sport-criteria-cutoffs
#15
Allison R Toole, Matthew P Ithurburn, Mitchell J Rauh, Timothy E Hewett, Mark V Paterno, Laura C Schmitt
Study Design Prospective cohort study. Background While meeting objective criteria cutoffs are recommended prior to return-to-sport (RTS) following ACL reconstruction (ACLR), the number of young athletes meeting recommended cutoffs and their impact on longitudinal sports participation are unknown. Objectives To test the hypothesis that a higher proportion of young athletes who met recommended cutoffs would maintain the same level of sports participation over the year following RTS clearance compared to those who did not...
October 7, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28989937/comparison-of-2-radiographic-techniques-for-measurement-of-tibiofemoral-joint-space-width
#16
Nabil Mehta, Jeffrey Duryea, Gary J Badger, Matthew R Akelman, Morgan H Jones, Kurt P Spindler, Braden C Fleming
BACKGROUND: No consensus is available regarding the best method for measuring tibiofemoral joint space width (JSW) on radiographs to quantify joint changes after injury. Studies that track articular cartilage thickness after injury frequently use patients' uninjured contralateral knees as controls, although the literature supporting this comparison is limited. PURPOSE: (1) To compare JSW measurements using 2 established measurement techniques in healthy control participants and (2) to determine whether the mean JSW of the uninjured contralateral knee in a cohort with anterior cruciate ligament (ACL) reconstruction is different from that obtained from a true control population...
September 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28989265/technical-considerations-in-revision-anterior-cruciate-ligament-acl-reconstruction-for-operative-techniques-in-orthopaedics
#17
Jeremy M Burnham, Elmar Herbst, Thierry Pauyo, Thomas Pfeiffer, Darren L Johnson, Freddie H Fu, Volker Musahl
As the incidence of anterior cruciate ligament (ACL) reconstruction continues to increase, the rate of revision surgery continues to climb. Revision surgery has inherent challenges that must be addressed in order to achieve successful results. The cause of the primary ACL reconstruction failure should be determined, and careful preoperative planning should be performed to address the cause(s) of failure. Each patient undergoing revision surgery should undergo a thorough history and physical examination, receive full length alignment radiographs, lateral radiographs, 45-degree flexion weight-bearing postero-anterior radiographs, and patellofemoral radiographs...
March 2017: Operative Techniques in Orthopaedics
https://www.readbyqxmd.com/read/28988312/contamination-occurs-during-acl-graft-harvesting-and-manipulation-but-it-can-be-easily-eradicated
#18
Daniel Pérez-Prieto, María E Portillo, Raúl Torres-Claramunt, Xavier Pelfort, Pedro Hinarejos, Joan C Monllau
PURPOSE: Why anterior cruciate ligament (ACL) autograft soaking in a 5 mg/ml vancomycin solution decreases the rate of infection has not been well-explained. One hypothesis is that grafts can be contaminated during harvesting and vancomycin eradicates the bacteria. The purpose of the present study is to assess how the vancomycin solution acts against ACL graft contamination during graft harvesting and preparation. METHODS: The study was carried out in three university hospitals over a period of 6 months...
October 7, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28987873/hip-joint-biomechanics-in-those-with-and-without-post-traumatic-knee-osteoarthritis-after-anterior-cruciate-ligament-injury
#19
E Wellsandt, J A Zeni, M J Axe, L Snyder-Mackler
BACKGROUND: Anterior cruciate ligament injury results in altered kinematics and kinetics in the knee and hip joints that persist despite surgical reconstruction and rehabilitation. Abnormal movement patterns and a history of osteoarthritis are risk factors for articular cartilage degeneration in additional joints. The purpose of this study was to determine if hip joint biomechanics early after anterior cruciate ligament injury and reconstruction differ between patients with and without post-traumatic knee osteoarthritis 5years after reconstruction...
October 2, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28987527/risk-factors-for-radiographic-progression-of-osteoarthritis-after-partial-meniscectomy-of-discoid-lateral-meniscus-tear
#20
J H Ahn, D M Kang, K J Choi
INTRODUCTION: Partial meniscectomy has been preferred in the treatment of discoid lateral meniscus (DLM) with tear, rather than total or subtotal meniscectomy, which could lead to late radiographic degenerative changes. HYPOTHESIS: One or more risk factors contribute to radiographic progression of osteoarthritis after partial meniscectomy of DLM tear. MATERIAL AND METHODS: Inclusion criteria were consecutive patients who underwent arthroscopic surgeries for DLM tear from January 2005 to December 2010 by one surgeon...
October 5, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
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