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Ligament cruciate anterior

Fei Yu, Hui Zeng, Ming Lei, De-Ming Xiao, Wei Li, Hao Yuan, Jian-Jing Lin
This study investigated the effects of SIRT1 gene knock-out on osteoarthritis in mice, and the possible roles of SREBP2 protein and the PI3K/AKT signaling pathway in the effects. Mice were randomly divided into a normal group and a SIRT1 gene knock-out group (6 mice in each group). In these groups, one side of the knee anterior cruciate ligament was traversed, and the ipsilateral medial meniscus was cut to establish an osteoarthritis model of knee joint. The countralateral synovial bursa was cut out, serving as controls...
October 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
E K Greska, N Cortes, S I Ringleb, J A Onate, B L Van Lunen
Previous studies have shown conflicting information regarding leg dominance as an etiological factor for the risk of anterior cruciate ligament (ACL) injuries. It remains unclear if lower extremity neuromechanical limb asymmetries exist in experienced athletes. The purpose of this study was to evaluate lower extremity neuromechanical effects of leg dominance in female collegiate soccer athletes during an unanticipated side-step cutting task. Twenty female collegiate soccer players completed an unanticipated side-step cutting task, using their dominant and non-dominant legs...
October 17, 2016: Scandinavian Journal of Medicine & Science in Sports
Elizabeth Wellsandt, Ashutosh Khandha, Kurt Manal, Michael J Axe, Thomas S Buchanan, Lynn Snyder-Mackler
Anterior cruciate ligament (ACL) injury results in altered knee joint mechanics which frequently continue even after ACL reconstruction. The persistence of altered mechanical loading of the knee is of concern due to its likely role in the development of post-traumatic osteoarthritis (OA). Joint contact forces are associated with post-traumatic OA development, but evaluation of factors influencing the magnitude of contact forces after ACL injury is needed to advance current strategies aimed at preventing post-traumatic OA...
October 17, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
Naruto Yoshida, Shun Kunugi, Sonoko Mashimo, Yoshihiro Okuma, Akihiko Masunari, Shogo Miyazaki, Tatsuya Hisajima, Shumpei Miyakawa
BACKGROUND: The purpose of this study is to examine the effects of different strike forms, during cutting, on knee joint angle and lower limb muscle activity. METHODS: Surface electromyography was used to measure muscle activity in individuals performing cutting manoeuvres involving either rearfoot strikes (RFS) or forefoot strikes (FFS). Three-dimensional motion analysis was used to calculate changes in knee angles, during cutting, and to determine the relationship between muscle activity and knee joint angle...
December 2016: Sports Medicine—Open
Ashraf Elsayed Alzeftawy, Ahmad Ali El-Daba
BACKGROUND: Cooling of local anesthetic potentiates its action and increases its duration. Magnesium sulfate (MgSo4) added to local anesthetic prolongs the duration of anesthesia and postoperative analgesia with minimal side effects. AIM: The aim of this prospective, randomized, double-blind study was to compare the effect of cold to 4°C bupivacaine 0.5% and Mg added to normal temperature (20-25°C) bupivacaine 0.5% during sonar-guided combined femoral and sciatic nerve blocks on the onset of sensory and motor block, intraoperative anesthesia, duration of sensory and motor block, and postoperative analgesia in arthroscopic anterior cruciate ligament (ACL) reconstruction surgery...
September 2016: Anesthesia, Essays and Researches
Jeong-Ku Ha, Dhong-Won Lee, Jin-Goo Kim
BACKGROUND: Numerous studies have elucidated the functional anatomy and biomechanics of the anterior cruciate ligament (ACL), as a result, double-bundle (DB) ACL reconstruction has received much attention and has become a popular choice because it gives better rotational stability. Many other studies, however, found no differences with respect to stability, and/or other clinical outcomes between the DB and single-bundle (SB) techniques. There is still not enough evidence as to whether the anatomical DB anterior cruciate ligament reconstruction (ACLR) is superior to anatomical SB reconstruction...
September 2016: Indian Journal of Orthopaedics
Mutlu Cobanoglu, Ferit Tufan Ozgezmez, Imran Kurt Omurlu, Ilhan Ozkan, Sevki Oner Savk, Emre Cullu
BACKGROUND: Anterior cruciate ligament (ACL) reconstruction with ST autograft is sometimes unsuccessful because of harvested thin graft. Magnetic resonance imaging (MRI) can be a useful tool to evaluate the thickness of the graft. This study is performed to evaluate whether there is any correlation between diameters and cross-sectional area (CSA) of the semitendinosus tendon (ST) on the preoperative magnetic MRI and the diameter of the 4-stranded ST autograft in ACL reconstruction. MATERIALS AND METHODS: Seventy patients who underwent single-bundle ACL reconstruction with 4-stranded ST for full-thickness ACL ruptures were included in this study...
September 2016: Indian Journal of Orthopaedics
Ravi Gupta, Gladson David Masih, Gaurav Chander, Vikas Bachhal
BACKGROUND: Despite improvements in instability after anterior cruciate ligament (ACL) reconstruction, associated intraarticular injuries remain a major cause of concern and important prognostic factor for long term results as it may lead to osteoarthritis. Delay in ACL reconstruction has been in variably linked to increase in these injuries but there is lack of consensus regarding optimal timing of reconstruction. The goal of this study was to investigate delay in surgery and other factors, associated with intraarticular injuries in ACL deficient knees...
September 2016: Indian Journal of Orthopaedics
Sufian S Ahmad, Johannes C Meyer, Anna M Krismer, Suhaib S Ahmad, Dimitrios S Evangelopoulos, Sven Hoppe, Sandro Kohl
PURPOSE: Clinical research in the area of anterior cruciate ligament (ACL) injury has shown substantial growth during the last decade. This was accompanied by the establishment of a wide range of outcome measures used to address the demands of clinical studies. The aim of this study was to evaluate outcome measures reported by highly cited level I trials in ACL research and identify factors influencing citation metrics. METHODS: The database of the Institute for Scientific Information (ISI) was utilized to screen journals under the subject categories "Orthopaedics", "Sports Sciences", "Radiology" and "General medicine" for the 50 most cited level I ACL trials based on predefined inclusion criteria...
October 14, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Guido Wierer, Armin Runer, Peter Gföller, Christian Fink, Christian Hoser
BACKGROUND: Postoperative extension deficits following anterior cruciate ligament (ACL) reconstruction can cause major limitation during daily life. The purpose of this study was to evaluate the efficiency of an all-arthroscopic approach and posterior capsule release for the treatment of persistent knee extension deficits following ACL reconstruction. METHODS: Between 2009 and 2013 a total of 10 patients with knee flexion contractures after ACL reconstruction were assessed following an all-arthroscopic approach and posterior capsulotomy...
October 12, 2016: Knee
R Brent Stansfield, Lisa Diponio, Cliff Craig, John Zeller, Edmund Chadd, Joshua Miller, Seetha Monrad
BACKGROUND: Medical students have difficulty performing and interpreting musculoskeletal physical examinations and interpreting the findings. Research has focused on students' knowledge deficits, but there are few direct assessments of students' ability to perform a hypothesis-driven physical examination (HDPE). We developed a novel musculoskeletal Objective Structured Clinical Exam (OSCE) focusing on HDPE skills for disorders of the shoulder, back and knee, and used it to explore medical student diagnostic reasoning...
October 14, 2016: BMC Medical Education
Larissa Correa Hermeto, Rafael De Rossi, Paulo Henrique de Affonseca Jardim, Aureo Evangelista Santana, Jaqueline de Carvalho Rinaldi, Luis Antonio Justulin
PURPOSE: To compare two different experimental models of osteoarthritis in rabbits: intra-articular collagenase injection and anterior cruciate ligament transection. METHODS: Ten adult rabbits were randomly divided in two groups: COLL (collagenase group) and ACLT (anterior cruciate ligament transection). The COLL group was treated with 0.5 ml collagenase solution (2mg collagenase/0.5 ml sterile PBS), and the ACTL group was subjected to anterior cruciate ligament...
September 2016: Acta Cirúrgica Brasileira
Eric C McCarty, Matthew J Kraeutler, Paula Langner, Shane Cook, Byron Ellis, Jenna M Godfrey
We conducted a study to identify and contrast patterns in the treatment of common injuries that occur in National Football League (NFL) players and National Collegiate Athletic Association (NCAA) Division I football players. Orthopedic team physicians for all 32 NFL and 119 NCAA Division I football teams were asked to complete a survey regarding demographics and preferred treatment of a variety of injuries encountered in football players. Responses were received from 31 (97%) of the 32 NFL and 111 (93%) of the 119 NCAA team physicians...
September 2016: American Journal of Orthopedics
Paul Rothenberg, Luis Grau, Lee Kaplan, Michael G Baraga
Football has the highest injury rate amongst popular American sports. Of those injuries that end seasons or careers, the knee is the most common culprit. This is of particular concern because knee injuries are most common in football. This article reviews 4 of the most common knee injuries in American football, with emphasis on epidemiology, risk factors, and treatment outcomes. The injuries reviewed are tears of the anterior cruciate ligament, medial collateral ligament, medial patellofemoral ligament, and posterior cruciate ligament...
September 2016: American Journal of Orthopedics
Eugenio Maria Pistone, Luca Laudani, Gianluca Camillieri, Alessandra Di Cagno, Gabriele Tomassi, Andrea Macaluso, Arrigo Giombini
OBJECTIVE: To assess the effects of adding a whole-body vibration protocol at optimal frequency (WBV-OF) to a traditional rehabilitation programme (TRP) early after anterior cruciate ligament reconstruction, on maximal strength and balance, in comparison with a traditional rehabilitation programme. DESIGN: A total of 34 anterior cruciate ligament reconstructed patients with hamstring-tendon graft underwent either 4 weeks of WBV-OF training in addition to a traditional rehabilitation programme, or a traditional rehabilitation programme only, starting from the first month after surgery...
September 28, 2016: Journal of Rehabilitation Medicine
Takeshi Oshima, Junsuke Nakase, Hitoaki Numata, Yasushi Takata, Hiroyuki Tsuchiya
BACKGROUND: The looped side of the semitendinosus tendon (ST) graft (i.e., the side inserted into the femoral tunnel during anterior cruciate ligament reconstruction) appears to be oval rather than round. The purpose of this study was to investigate the cross section of the fourfold semitendinosus tendon graft and, more specifically, the differences in pressure exerted by a rounded rectangular tunnel versus a round femoral tunnel. METHODS: Seven STs were harvested from cadaveric knees and a fourfold ST graft was made...
December 2016: Journal of Experimental Orthopaedics
Mohammad A Yabroudi, Haukur Björnsson, Andrew D Lynch, Bart Muller, Kristian Samuelsson, Majd Tarabichi, Jón Karlsson, Freddie H Fu, Christopher D Harner, James J Irrgang
BACKGROUND: Revision anterior cruciate ligament (ACL) reconstruction surgery occurs in 5% to 15% of individuals undergoing ACL reconstruction. Identifying predictors for revision ACL surgery is of essence in the pursuit of creating adequate prevention programs and to identify individuals at risk for reinjury and revision. PURPOSE: To determine predictors of revision ACL surgery after failed primary ACL reconstruction. STUDY DESIGN: Case-control study; Level of evidence, 3...
September 2016: Orthopaedic Journal of Sports Medicine
Erhan Sukur, Yunus Emre Akman, Ahmet Senel, Ethem Ayhan Unkar, Huseyin Nevzat Topcu, And Yusuf Ozturkmen
BACKGROUND: Among the many factors that determine the outcome following anterior cruciate ligament (ACL) reconstruction, the position of the femoral tunnel is known to be critically important and is still the subject of extensive research. OBJECTIVE: We aimed to retrospectively compare the outcomes of arthroscopic ACL reconstruction using transtibial (TT) or anteromedial (AMP) drilling techniques for femoral tunnel placement. METHODS: ACL reconstruction was performed using the TT technique in 49 patients and the AMP technique in 56 patients...
2016: Open Orthopaedics Journal
Gulcan Harput, Jennifer Sebert Howard, Carl Mattacola
Study Design Cross-sectional, controlled laboratory study. Background Quantification of muscular activation during different phases of functional activities is important to understand activation deficits in individuals who have undergone anterior cruciate ligament reconstruction (ACLR). Objectives To compare activation levels of vastus medialis (VM), medial hamstrings (MH) and gluteus medius (GMed) muscles during the different phases of weight bearing tasks between individuals who had undergone ACLR and healthy controls...
October 12, 2016: Journal of Orthopaedic and Sports Physical Therapy
Marie Bagger Bohn, Annemette Krintel Petersen, Dennis Brandborg Nielsen, Henrik Sørensen, Martin Lind
BACKGROUND: Anterior cruciate ligament (ACL) deficiency leads to altered stability of the knee. The purpose of this study was to compare the dynamic, rotational stability of the knee, expressed as rotational stiffness, between anterior cruciate ligament-deficient (ACLD) knees, their contralateral intact knees (ACLI) and a knee healthy control group during walking, running and 90° pivoting. We hypothesized a larger tibial internal rotation, a smaller knee joint external moment and a lower rotational stiffness in the ACLD group compared to the ACLI and the control group...
December 2016: Journal of Experimental Orthopaedics
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