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https://www.readbyqxmd.com/read/29457434/-minimally-invasive-sinus-tarsal-approach-versus-conventional-l-shaped-lateral-approach-in-treating-calcaneal-fractures-a-meta-analysis
#1
Min-Hao Wu, Wen-Chao Sun, Fei-Fei Yan, Zhi-Qiang Hou, Fan Feng, Lin Cai
OBJECTIVE: To compare efficacy and safety of minimally invasive sinus tarsal approach versus conventional L-shaped lateral approach in treating calcaneal fractures. METHODS: The studies concerning about randomized controlled trial and non-randomized controlled trial of minimally invasive sinus tarsal approach versus conventional L-shaped lateral approach in treating calcaneal fractures from the time of creating database to March, 2017 were searched from PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), EMbase, ISI Web of Knowledge databases, VIP, CNKI, CBM and Wan Fang...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29456807/potential-of-polymeric-particles-as-future-vaccine-delivery-systems-adjuvants-for-parenteral-and-non-parenteral-immunization-against-tuberculosis-a-systematic-review
#2
REVIEW
Farzad Khademi, Mohammad Derakhshan, Arshid Yousefi-Avarvand, Mohsen Tafaghodi
Objectives: Production of effective tuberculosis (TB) vaccine is necessity. However, the development of new subunit vaccines is faced with concerns about their weak immunogenicity. To overcome such problems, polymers-based vaccine delivery systems have been proposed to be used via various routes. The purpose of this study was to determine the potential of polymeric particles as future vaccine delivery systems/adjuvants for parenteral and non-parenteral immunization against TB. Materials and Methods: PubMed, Scopus, Science-Direct, and the ISI web of knowledge databases were searched for related keywords...
February 2018: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29456500/auditory-memory-decay-as-reflected-by-a-new-mismatch-negativity-score-is-associated-with-episodic-memory-in-older-adults-at-risk-of-dementia
#3
Daria Laptinskaya, Franka Thurm, Olivia C Küster, Patrick Fissler, Winfried Schlee, Stephan Kolassa, Christine A F von Arnim, Iris-Tatjana Kolassa
The auditory mismatch negativity (MMN) is an event-related potential (ERP) peaking about 100-250 ms after the onset of a deviant tone in a sequence of identical (standard) tones. Depending on the interstimulus interval (ISI) between standard and deviant tones, the MMN is suitable to investigate the pre-attentive auditory discrimination ability (short ISIs, ≤ 2 s) as well as the pre-attentive auditory memory trace (long ISIs, >2 s). However, current results regarding the MMN as an index for mild cognitive impairment (MCI) and dementia are mixed, especially after short ISIs: while the majority of studies report positive associations between the MMN and cognition, others fail to find such relationships...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29455685/health-technology-assessment-evidence-on-e-health-m-health-technologies-evaluating-the-transparency-and-thoroughness
#4
Vladimir Vukovic, Carlo Favaretti, Walter Ricciardi, Chiara de Waure
OBJECTIVES: Evaluation is crucial for integration of e-Health/m-Health into healthcare systems and health technology assessment (HTA) could offer sound methodological basis for these evaluations. Aim of this study was to look for HTA reports on e-Health/m-Health technologies and to analyze their transparency, consistency and thoroughness, with the goal to detect areas that need improvement. METHODS: PubMed, ISI-WOS, and University of York - Centre for Reviews and Dissemination-electronic databases were searched to identify reports on e-Health/m-Health technologies, published up until April 1, 2016...
February 19, 2018: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/29455377/prevalence-of-bacterial-vaginosis-in-pregnant-and-non-pregnant-iranian-women-a-systematic-review-and-meta-analysis
#5
REVIEW
Sahar Sabour, Mohsen Arzanlou, Hamid Vaez, Giti Rahimi, Amirhossein Sahebkar, Farzad Khademi
PURPOSE: Bacterial vaginosis (BV) is a vaginal disorder which occurs either symptomatic or asymptomatic because of an imbalance between H2 O2 -producing Lactobacillus and Gardnerella vaginalis in the vagina. This systematic review and meta-analysis is the first to determine the prevalence of BV in pregnant and non-pregnant women in Iran. METHODS: We used national (SID, Irandoc, Iranmedex and Magiran) and international (PubMed, Scopus, Google Scholar and ISI web of knowledge) electronic databases to systematically search and collect available studies using related keywords (up to 1 December 2017)...
February 17, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29454965/detection-of-synchronized-burst-firing-in-cultured-human-induced-pluripotent-stem-cell-derived-neurons-using-a-4-step-method
#6
N Matsuda, A Odawara, H Kato, N Okuyama, R Yokoi, I Suzuki
Human induced pluripotent stem cell-derived neurons are promising for use in toxicity evaluations in nonclinical studies. The multi-electrode array (MEA) assay is used in such evaluation systems because it can measure the electrophysiological function of a neural network noninvasively and with high throughput. Synchronized burst firing (SBF) is the main analytic parameter of pharmacological effects in MEA data, but an accurate method for detecting SBFs has not been established. In this study, we present a 4-step method that accurately detects a target SBF confirmed by the researcher's interpretation of a raster plot...
February 15, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29454521/hepatitis-b-vaccination-and-the-putative-risk-of-central-demyelinating-diseases-a-systematic-review-and-meta-analysis
#7
Julie Mouchet, Francesco Salvo, Emanuel Raschi, Elisabetta Poluzzi, Ippazio Cosimo Antonazzo, Fabrizio De Ponti, Bernard Bégaud
BACKGROUND: The anti-hepatitis B immunization campaigns launched in the early 1990s were a major public health breakthrough and targeted various populations (at-risk adults, newborns, adolescents). However, debate is still active about a possible link between this vaccine and central demyelination. This study provides a pooled estimate of this risk based on a comprehensive review and meta-analysis of all available epidemiologic studies. METHODS: A systematic review was conducted in Medline, Embase, ISI Web of Science and the Cochrane Library from database inception to 10 May 2017...
February 14, 2018: Vaccine
https://www.readbyqxmd.com/read/29453926/sleep-disorder-prevalence-in-at-risk-adolescents-and-potential-effects-of-nightmare-triad-syndrome
#8
Natalia D McIver, Barry Krakow, Jessica Krakow, Michael R Nadorff, Victor A Ulibarri, Robert Baade
Objective At-risk high school students, those considered to have a higher probability for academic failure or dropping out, were assessed for various sleep disorders. Effects were compared between students with and without the nightmare triad syndrome (NTS+), the sleep disorders' cluster of frequent nightmares, insomnia disorder and suspected sleep-disordered breathing (SDB). Methods Data were gathered at a charter school for at-risk youth using: computer based surveys, physical airway exams, and mental health interviews by school social worker...
February 17, 2018: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/29453672/the-effect-of-n-3-pufas-on-circulating-adiponectin-and-leptin-in-patients-with-type-2-diabetes-mellitus-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#9
Azam Rezaei Farimani, Mitra Hariri, Mohsen Azimi-Nezhad, Abasalt Borji, Sadegh Zarei, Elham Hooshmand
AIM: N-3 PUFAs can potentially influence levels of inflammatory and non-inflammatory adipokines. Given the contradictory effects of n-3 PUFAs on serum levels of adipokines in type 2 diabetes, we conducted a systematic review and meta-analysis study of randomized placebo-controlled clinical trials that examined the effects of n-3 PUFAs on serum levels of leptin and adiponectin in patients with type 2 diabetes. METHODS: The electronic databases, without regard to language restrictions including PubMed/Medline, Google Scholar, SCOPUS and ISI Web of Science until August 2017, were used to identify randomized controlled trials that assessed the effect of n-3 PUFAs on serum leptin and adiponectin concentrations in type 2 diabetes...
February 16, 2018: Acta Diabetologica
https://www.readbyqxmd.com/read/29453625/effects-of-feedstock-and-co-culture-of-lactobacillus-fermentum-and-wild-saccharomyces-cerevisiae-strain-during-fuel-ethanol-fermentation-by-the-industrial-yeast-strain-pe-2
#10
Vanda R Reis, Ana Paula G Bassi, Bianca C Cerri, Amanda R Almeida, Isis G B Carvalho, Reinaldo G Bastos, Sandra R Ceccato-Antonini
Even though contamination by bacteria and wild yeasts are frequently observed during fuel ethanol fermentation, our knowledge regarding the effects of both contaminants together is very limited, especially considering that the must composition can vary from exclusively sugarcane juice to a mixture of molasses and juice, affecting the microbial development. Here we studied the effects of the feedstock (sugarcane juice and molasses) and the co-culture of Lactobacillus fermentum and a wild Saccharomyces cerevisiae strain (rough colony and pseudohyphae) in single and multiple-batch fermentation trials with an industrial strain of S...
February 16, 2018: AMB Express
https://www.readbyqxmd.com/read/29452165/the-beneficial-role-of-early-exercise-training-following-stroke-and-possible-mechanisms
#11
REVIEW
Ying Xing, Si-Dong Yang, Fang Dong, Man-Man Wang, Ya-Shuo Feng, Feng Zhang
Exercise training is a regular therapy for stroke patients in clinic. However, whether the early exercise is beneficial for stroke patients is still controversial. The review was performed in databases of OVID, PUBMED, and ISI Web of Science, from respective inception to December 2017. In this review, we summarize the effect of different exercise intensity, initiation time, and style on ischemic stroke. Moreover, the possible mechanism is also discussed. The conclusion is that the voluntary exercise is better in promoting the functional recovery following stroke compared to forced exercise; too early initiated exercise might play a harmful role following stroke, while early initiated exercise might exert benefits after stroke; mild and moderate intensity exercise training could generate better neuroprotection in comparison with high intensity exercise training; early excise training could regulate the process of brain edema, cell apoptosis, oxidative damage, stem cells and other mechanisms in order to exert neuroprotection for brain...
February 13, 2018: Life Sciences
https://www.readbyqxmd.com/read/29451994/stroop-task-related-brain-activity-in-patients-with-insomnia-changes-after-cognitive-behavioral-therapy-for-insomnia
#12
Jeong Yeon Hwang, Nambeom Kim, Soohyun Kim, Juhyun Park, Jae-Won Choi, Seog Ju Kim, Chang-Ki Kang, Yu Jin Lee
OBJECTIVE/BACKGROUND: In the present study, we compared differences in brain activity during the Stroop task between patients with chronic insomnia disorder (CID) and good sleepers (GS). Furthermore, we evaluated changes in Stroop task-related brain activity after cognitive-behavioral therapy for insomnia (CBT-I). PARTICIPANTS/METHODS: The final analysis included 21 patients with CID and 25 GS. All participants underwent functional magnetic resonance imaging (fMRI) while performing the color-word Stroop task...
February 16, 2018: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/29449026/validity-of-a-single-ptsd-checklist-item-to-screen-for-insomnia-in-survivors-of-critical-illness
#13
Elizabeth C Parsons, Catherine L Hough, Michael V Vitiello, Brian Palen, Douglas Zatzick, Dimitry S Davydow
BACKGROUND: There is no insomnia screening tool validated in intensive care unit (ICU) survivors. OBJECTIVES: To examine the validity of a single item from the PTSD checklist-Civilian version (PCL-C) to detect insomnia by Insomnia Severity Index (ISI) METHODS: We performed a secondary analysis of data from a longitudinal investigation in 120 medical-surgical ICU survivors. At 1 year post-ICU, patients completed ISI, PCL-C, and Medical Short-Form 12 (SF-12) by telephone...
February 12, 2018: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/29448468/memory-induced-resonancelike-suppression-of-spike-generation-in-a-resonate-and-fire-neuron-model
#14
Romi Mankin, Sander Paekivi
The behavior of a stochastic resonate-and-fire neuron model based on a reduction of a fractional noise-driven generalized Langevin equation (GLE) with a power-law memory kernel is considered. The effect of temporally correlated random activity of synaptic inputs, which arise from other neurons forming local and distant networks, is modeled as an additive fractional Gaussian noise in the GLE. Using a first-passage-time formulation, in certain system parameter domains exact expressions for the output interspike interval (ISI) density and for the survival probability (the probability that a spike is not generated) are derived and their dependence on input parameters, especially on the memory exponent, is analyzed...
January 2018: Physical Review. E
https://www.readbyqxmd.com/read/29448003/increased-hippocampal-prefrontal-functional-connectivity-in-insomnia
#15
Jeanne Leerssen, Rick Wassing, Jennifer R Ramautar, Diederick Stoffers, Oti Lakbila-Kamal, Joy Perrier, Jessica Bruijel, Jessica C Foster-Dingley, Moji Aghajani, Eus J W van Someren
Insomnia Disorder (ID) is the second-most common mental disorder and has a far-reaching impact on daytime functioning. A meta-analysis indicates that, of all cognitive domains, declarative memory involving the hippocampus is most affected in insomnia. Hippocampal functioning has consistently been shown to be sensitive to experimental sleep deprivation. Insomnia however differs from sleep deprivation in many aspects, and findings on hippocampal structure and function have been equivocal. The present study used both structural and resting-state functional Magnetic Resonance Imaging in a larger sample than previously reported to evaluate hippocampal volume and functional connectivity in ID...
February 12, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29445355/plasma-levels-of-myonectin-but-not-myostatin-or-fibroblast-derived-growth-factor-21-are-associated-with-insulin-resistance-in-adult-humans-without-diabetes-mellitus
#16
Freddy J K Toloza, Jose O Mantilla-Rivas, Maria C Pérez-Matos, Maria L Ricardo-Silgado, Martha C Morales-Alvarez, Jairo A Pinzón-Cortés, Maritza Pérez-Mayorga, Martha L Arévalo-Garcia, Giovanni Tolosa-González, Carlos O Mendivil
Background: Myokines are a group of protein mediators produced by skeletal muscle under stress or physical exertion. Even though their discovery and effects in cell culture and animal models of disease have elicited great enthusiasm, very little is known about their role in human metabolism. We assessed whether plasma concentrations of three known myokines [myonectin, myostatin, and fibroblast-derived growth factor 21 (FGF-21)] would be associated with direct and indirect indicators of insulin resistance (IR) in individuals who did not have a diagnosis of diabetes...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29445171/electrophysiological-evidence-of-memory-based-detection-of-auditory-regularity-violations-in-anesthetized-mice
#17
Jari L O Kurkela, Arto Lipponen, Iiris Kyläheiko, Piia Astikainen
In humans, automatic change detection is reflected by an electrical brain response called mismatch negativity (MMN). Mismatch response is also elicited in mice, but it is unclear to what extent it is functionally similar to human MMN. We investigated this possible similarity by recording local field potentials from the auditory cortex of anesthetized mice. First, we tested whether the response to stimulus changes reflected the detection of regularity violations or adaptation to standard stimuli. Responses obtained from an oddball condition, where occasional changes in frequency were presented amongst of a standard sound, were compared to responses obtained from a control condition, where no regularities existed...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29441477/betel-nut-chewing-and-the-risk-of-chronic-kidney-disease-evidence-from-a-meta-analysis
#18
REVIEW
Meng Wang, Si-Yi Yu, Zheng-Tao Lv, Ying Yao
PURPOSE: To investigate and quantify the potential association between betel nut chewing and the risk of chronic kidney disease (CKD). METHODS: We searched five online databases including PubMed, EMBASE, ISI Web of Science, Wanfang and CNKI to identify observational studies that published prior to May, 1, 2017. The primary outcome was the association between betel nut chewing and CKD expressed as odds ratio (OR) and the corresponding 95% confidence interval (95%CI) after adjustment for other covariates...
February 13, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29440903/association-of-the-matrix-metalloproteinase-3-polymorphisms-rs679620-and-rs3025058-with-ischemic-stroke-risk-a-meta-analysis
#19
Qi-Wei Zhang
Purpose: The relationship of the matrix metalloproteinase-3 ( MMP-3 ) polymorphisms rs679620 and rs3025058 with ischemic stroke has received much attention. The aim of the present study was to perform a meta-analysis of published case-control studies to evaluate the cumulative evidence. Methods: We performed a search of ISI Web of Science, Embase, PubMed, and China National Knowledge Infrastructure databases. Pooled odds ratios (ORs) were appropriately derived from fixed-effects or random-effects models...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29439273/effects-of-diet-on-telomere-length-systematic-review-and-meta-analysis
#20
Lisiane Marçal Pérez, Marina Azambuja Amaral, Eduardo Mundstock, Florencia M Barbé-Tuana, Fátima Teresinha Costa Rodrigues Guma, Marcus H Jones, Denise Cantarelli Machado, Edgar E Sarria, Maximiniano Marques E Marques, Luiza Tweedie Preto, Matias Epifanio, João Guilherme Meinem Garbin, Rita Mattiello
BACKGROUND: The goal of this systematic review and meta-analysis is to determine the effect of diet on telomere length. METHODS: We searched the following databases: MEDLINE, Embase, LILACS, CINAHL, ISI Web of Science, and Scopus, as well as the Cochrane Central Register of Controlled Trials and the National Institutes of Health, from inception to December 2016. Articles that assessed effects of diet on telomere length were included. RESULTS: A total of 2,128 studies were identified, 30 were read in full, and 7 were systematically reviewed...
February 13, 2018: Public Health Genomics
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