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https://www.readbyqxmd.com/read/29231076/selective-autophagy-restricts-il-9-secretion-from-th9-cells-relevance-in-cancer-growth
#1
Isis Benoit-Lizon, Elise Jacquin, Lionel Apetoh
No abstract text is available yet for this article.
December 12, 2017: Cell Cycle
https://www.readbyqxmd.com/read/29230208/ramadan-fasting-exerts-immunomodulatory-effects-insights-from-a-systematic-review
#2
Mohammad Adawi, Abdulla Watad, Stav Brown, Khadija Aazza, Hicham Aazza, Mohamed Zouhir, Kassem Sharif, Khaled Ghanayem, Raymond Farah, Hussein Mahagna, Stefano Fiordoro, Samir Giuseppe Sukkar, Nicola Luigi Bragazzi, Naim Mahroum
Ramadan is the ninth month of the Islamic lunar calendar and is observed by Muslims as a month of fasting. All Muslim adults are expected to fast; nevertheless certain subgroups, including sick, frail subjects, and pregnant women, among others, are exempted. Ramadan fasting has been shown to impact on body systems in different manners. The influence of Ramadan fasting on immune system regulation remains elusive; however, immune system changes, such as the modulation of body response to various infectious, stressful, and other harmful events, are of great interest during fasting...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29230178/human-cardiac-31p-mr-spectroscopy-at-3-tesla-cannot-detect-failing-myocardial-energy-homeostasis-during-exercise
#3
Adrianus J Bakermans, Jason N Bazil, Aart J Nederveen, Gustav J Strijkers, S Matthijs Boekholdt, Daniel A Beard, Jeroen A L Jeneson
Phosphorus-31 magnetic resonance spectroscopy (31P-MRS) is a unique non-invasive imaging modality for probing in vivo high-energy phosphate metabolism in the human heart. We investigated whether current 31P-MRS methodology would allow for clinical applications to detect exercise-induced changes in (patho-)physiological myocardial energy metabolism. Hereto, measurement variability and repeatability of three commonly used localized 31P-MRS methods [3D image-selected in vivo spectroscopy (ISIS) and 1D ISIS with 1D chemical shift imaging (CSI) oriented either perpendicular or parallel to the surface coil] to quantify the myocardial phosphocreatine (PCr) to adenosine triphosphate (ATP) ratio in healthy humans (n = 8) at rest were determined on a clinical 3 Tesla MR system...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29229208/assessment-and-treatment-at-a-pain-clinic-a-one-year-follow-up-of-patients-with-chronic-pain
#4
Andrea Hållstam, Monika Löfgren, Lina Benson, Christer Svensén, Britt-Marie Stålnacke
BACKGROUND AND AIMS: Pain is one of the most common reasons for patients to seek primary health care. Pain relief is likely to be achieved for patients suffering from acute pain, but for individuals with chronic pain it is more likely that the condition will persist. These patients have the option of being referred to specialised pain clinics. However, the complexity surrounding chronic pain patients is not well studied in these settings. This study aimed to describe patients with chronic pain referred to a pain clinic by using the information submitted during their first visit and one year later and also to identify associations between baseline characteristics and improvements in health-related quality of life in the follow-up...
October 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29229060/development-and-validation-of-prediction-equations-for-spinal-curve-angles-based-on-skin-surface-measurements
#5
Tássia S Furlanetto, Eduardo B C de Oliveira, Cláudia T Candotti, Adriane Vieira, Paula V de Mesquita, Isis J R L Navarro, Jefferson F Loss
OBJECTIVE: The purpose of this study was to develop, assess the reliability of, and validate prediction equations that estimate the sagittal curves of the spine from the skin surface. METHODS: Forty digital panoramic radiographs were used to develop the prediction equation, and 59 radiographs were used to assess reliability and validate the equations. For evaluation of the thoracic and lumbar curves, anatomical reference points were marked on the vertebral body, spinous process, and skin surface at the C6, C7, T2, T4, T6, T8, T10, T12, L2, L4, and S2 vertebrae...
November 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29228747/the-association-of-matrix-metalloproteinase-9-promoter-polymorphisms-with-gastric-cancer-risk-a-meta-analysis
#6
Ziheng Peng, Jinhai Jia, Wenjian Gong, Xuehan Gao, Peiru Ma, Zhucheng Jin, Yue Fan, Yanchu Li, Xiaolin Zhang
Purpose: A variety of studies have observed that the single nucleotide polymorphisms (SNPs) matrix metalloproteinase-9 (MMP-9) gene may be associated with the risk of gastric cancer(GC), and a cytosine (C) to thymine (T) mutation at the -1562 site of the MMP-9 gene promoter is reported to be closely related to the susceptibility. However, because of the conflicting results of these studies, we undertook a systematic meta-analysis to assess the association between the SNPs and the risk of gastric cancer...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29228671/metformin-ameliorates-skeletal-muscle-insulin-resistance-by-inhibiting-mir-21-expression-in-a-high-fat-dietary-rat-model
#7
Jinyang Wang, Yanbin Gao, Lijun Duan, Suhong Wei, Jing Liu, Liming Tian, Jinxing Quan, Qi Zhang, Juxiang Liu, Jinkui Yang
Insulin resistance (IR) plays a major role in the pathogenesis of abdominal obesity, hypertension, coronary heart disease, atherosclerosis and diabetes. miR-21 and TGF-β/smads is closely related to IR. However, it remained elusive whether metformin improved skeletal muscle insulin resistance (IRSM) by regulating miR-21 and its target signal TGF-β1/smads expression. In this study, high-fat diet rats with IR model and IR-skeletal muscle L6 cells (L6-SMCs) model were established, insulin sensitive index (ISI) and Homeostasis model assessment of IR (HOMA-IR) were applied, miR-21 and TGF-β1/smads mRNA expression were examined by RT-PCR, smad3 and smad7 protein were detected by western-blotting and laser scanning confocal microscopy (LSCM), the valid target of miR-21 was detected by luciferase reporter gene assay...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29228348/flaxseed-supplementation-on-glucose-control-and-insulin-sensitivity-a-systematic-review-and-meta-analysis-of-25-randomized-placebo-controlled-trials
#8
Mohsen Mohammadi-Sartang, Zahra Sohrabi, Reza Barati-Boldaji, Hamidreza Raeisi-Dehkordi, Zohreh Mazloom
Context: The results of human clinical trials investigating the effects of flaxseed on glucose control and insulin sensitivity are inconsistent. Objective: The present study aimed to systematically review and analyze randomized controlled trials assessing the effects of flaxseed consumption on glycemic control. Data Sources: PubMed, Medline via Ovid, SCOPUS, EMBASE, and ISI Web of Sciences databases were searched up to November 2016. Study Selection: Clinical trials in which flaxseed or its products were administered as an intervention were included...
December 8, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/29228127/antibiotic-resistance-and-the-risk-of-recurrent-bacteremia
#9
Sjoukje H S Woudt, Sabine C de Greeff, Annelot F Schoffelen, Anne L M Vlek, Marc J M Bonten
Background: Direct health effects of antibiotic resistance are difficult to assess. We quantified the risk of recurrent bacteremia associated with antibiotic resistance. Methods: We extracted antimicrobial susceptibility testing data on blood isolates of Enterobacteriaceae, Pseudomonas spp., Enterococcus spp. and Staphylococcus aureus from the Dutch surveillance system for antimicrobial resistance between 2008 and 2017. First and first recurrent (4-30days) bacteremia episodes were categorized as susceptible, single non-susceptible or co-non-susceptible (I/R), to 3rd generation cephalosporins -/+ carbapenems (Enterobacteriaceae), ceftazidime -/+ carbapenems (Pseudomonas spp...
December 7, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29228093/correctness-of-self-reported-task-durations-a-systematic-review
#10
Jean A Pulido, Lope H Barrero, Svend Erik Mathiassen, Jack T Dennerlein
Objectives: Duration of tasks in a job is an essential interest in occupational epidemiology. Such duration is frequently measured using self-reports, which may, however, be associated with both bias and random errors. The present systematic literature review examines the correctness of self-reported durations of tasks, i.e. the extent to which they differ from more valid reference data due to either systematic or random errors, and factors influencing this correctness, with particular emphasis on the assessment of exposures of relevance to musculoskeletal disorders...
December 6, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29226776/a-journal-level-analysis-of-progress-in-transplantation
#11
Thomas Feeley, Seyoung Lee, Shin-Il Moon
CONTEXT: Citations to articles published in academic journals represent a proxy for influence in bibliometrics. OBJECTIVE: To measure the journal impact factor for Progress in Transplantation over time and to also identify related journals indexed in transplantation and surgery. DESIGN: Data from Journal Citation Reports (ISI web of science) were used to rank Progress in Transplantation compared to peer journals using journal impact and journal relatedness measures...
January 1, 2017: Progress in Transplantation
https://www.readbyqxmd.com/read/29224125/substitution-of-soybean-meal-with-fermented-jatropha-kernel-meal-effect-on-growth-performance-body-composition-and-metabolic-enzyme-activity-of-labeo-rohita
#12
Vikas Phulia, Parimal Sardar, Narottam Prasad Sahu, Femi John Fawole, N Shamna, Subodh Gupta
A 60-day feeding trial was conducted to evaluate the nutritional potential of fermented Jatropha kernel meal (FJKM) in the diets of rohu, Labeo rohita, fingerlings. Four iso-nitrogenous (336 g kg-1) and iso-energetic (20 MJ kg-1) diets containing 0, 100, 200, and 300 g kg-1 FJKM in replacement of 0, 33.3, 66.7, and 100% soybean meal protein, respectively, were prepared and designated as control, T1, T2, and T3, respectively. A total of 180 acclimatized fish (average weight 6.05 ± 0.04 g) were equally distributed into four experimental groups in triplicates, and were fed their respective diets to satiation twice daily at 10:00 h and 18:00 h...
December 9, 2017: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/29223453/hbv-reactivation-in-rheumatic-diseases-patients-under-therapy-a-meta-analysis
#13
REVIEW
Mohsen Moghoofei, Shayan Mostafaei, Amir Ashraf-Ganjouei, Hoda Kavosi, Mahdi Mahmoudi
BACKGROUND: Hepatitis B is one of the most common infectious diseases worldwide. In patients undergoing immunosuppressive therapy such as rheumatic diseases, reactivation of Hepatitis B virus (HBV) is considered clinically important. This systematic review and meta-analysis were performed to determine the prevalence rate of HBV reactivation in rheumatic patients from different parts of the world. It is worth mentioning that the aim of the current study was to report the prevalence of HBV with the application of meta-analysis...
December 6, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29221812/role-of-immune-cells-in-crystal-induced-kidney-fibrosis
#14
REVIEW
Ermanila Dhana, Isis Ludwig-Portugall, Christian Kurts
Chronic kidney diseases can lead to kidney fibrosis, which can be considered a futile attempt of tissue healing to replaces functional kidney tissue with connective tissue, basically forming a scar. Chronic inflammation is a frequent cause of kidney fibrosis. Classical as well as recently discovered immune cell subsets and their molecular mediators have been intensively investigated for their contribution to kidney fibrosis and their potential as therapeutic targets. Here we review the current knowledge about the role of immune cells in crystal-induced renal fibrosis...
December 5, 2017: Matrix Biology: Journal of the International Society for Matrix Biology
https://www.readbyqxmd.com/read/29219061/effect-of-conjugated-linoleic-acid-supplementation-on-serum-leptin-concentration-a-systematic-review-and-meta-analysis
#15
Fahimeh Haghighatdoost, Mitra Hariri
BACKGROUND: There are controversies regarding the effect of conjugated linoleic acid (CLA) on serum leptin. OBJECTIVE: To conduct a meta-analysis of randomized controlled trials (RCTs) to assess the effect of CLA on serum leptin concentrations. METHOD: Databases such as Ovid, PubMed/Medline, SCOPUS, Google Scholar, and ISI databases up to January 2017 were searched. The searches included RCTs conducted among human adults, and studies on the effect of conjugated linoleic acid on serum leptin concentrations as outcome variables...
December 7, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29217495/efficacy-of-violet-oil-a-traditional-iranian-formula-in-patients-with-chronic-insomnia-a-randomized-double-blind-placebo-controlled-study
#16
Zohre Feyzabadi, Fariborz Rezaeitalab, Shapour Badiee, Ali Taghipour, Fatemeh Moharari, Atefeh Soltanifar, Mohammad Reza Ahmadpour
ETHNOPHARMACOLOGICAL RELEVANCE: Violet oil is an ancient herbal drug which has been extensively used to treat insomnia in traditional Iranian Medicine clinics. Violet oil is an almond or sesame oil-based extract of Viola odorata, which is administered as nasal drops. This study aimed to evaluate the efficacy of Violet oil in the treatment of insomnia. METHODS AND MATERIALS: This study was conducted as a 3-arm double-blind randomized trial. A total of 75 patients with chronic insomnia were enrolled and randomly assigned to three groups in Traditional Iranian Medicine Clinic of Mashhad University of Medical Sciences, Mashhad, Iran...
December 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29212081/in-patients-with-chronic-kidney-disease-short-term-blood-pressure-variability-is-associated-with-the-presence-and-severity-of-sleep-disorders
#17
Martino F Pengo, Donatella Ioratti, Valeria Bisogni, Verdiana Ravarotto, Barbara Rossi, Luciana Bonfante, Francesca Simioni, Federico Nalesso, Giuseppe Maiolino, Lorenzo A Calò
BACKGROUND/AIMS: In chronic kidney disease (CKD) patients blood pressure variability (BPV) is associated with poor outcome. Sleep disturbances alter BP profiles in hypertensives but their influence on BPV in CKD patients is unknown. We screened a cohort of CKD/ESRD patients to investigate whether sleep quality impacts on BPV. METHODS: Consecutive CKD patients' sleep quality was assessed using validated questionnaires (Epworth Sleepiness Scale-ESS); International Restless legs scale-IRLS; Functional Outcomes of Sleep Questionnaire-FOSQ: Insomnia Severity Index-ISI; STOP-Bang)...
November 28, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29211813/scientometric-study-of-the-effects-of-exposure-to-non-ionizing-electromagnetic-fields-on-fertility-a-contribution-to-understanding-the-reasons-of-partial-failure
#18
Nicola Bernabò, Rosa Ciccarelli, Luana Greco, Alessandra Ordinelli, Mauro Mattioli, Barbara Barboni
The exposure to Non-Ionizing-Electromagnetic Fields (NI-EMFs) is often indicated as a cofactor responsible for the fertility reduction, which has been described in recent years. Despite the great interest in this topic and the research effort in exploring it, to date, there are no reliable data. Therefore, we carried out a scientometric analysis of the scientific literature published in peer reviewed Journals concerning this topic to better understand the reasons of this partial failure. To this aim, we identified and analysed 104 papers, published in last 26 years in peer-reviewed Journals, present in ISI Web of Knowledge Core Collection...
2017: PloS One
https://www.readbyqxmd.com/read/29209029/an-in-vitro-assay-to-measure-antibody-mediated-inhibition-of-p-berghei-sporozoite-invasion-against-p-falciparum-antigens
#19
Ana Rodríguez-Galán, Ahmed M Salman, Georgina Bowyer, Katharine A Collins, Rhea J Longley, Florian Brod, Marta Ulaszewska, Katie J Ewer, Chris J Janse, Shahid M Khan, Julius C Hafalla, Adrian V S Hill, Alexandra J Spencer
A large research effort is currently underway to find an effective and affordable malaria vaccine. Tools that enable the rapid evaluation of protective immune responses are essential to vaccine development as they can provide selection criteria to rank order vaccine candidates. In this study we have revisited the Inhibition of Sporozoite Invasion (ISI) assay to assess the ability of antibodies to inhibit sporozoite infection of hepatocytes. By using GFP expressing sporozoites of the rodent parasite P. berghei we are able to robustly quantify parasite infection of hepatocyte cell lines by flow cytometry...
December 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29206241/corrigendum-differential-regulation-of-thyroid-hormone-metabolism-target-genes-during-non-thyroidal-illness-syndrome-triggered-by-fasting-or-sepsis-in-adult-mice
#20
Klaus N Fontes, Adriana Cabanelas, Flavia F Bloise, Cherley Borba Vieira de Andrade, Luana L Souza, Marianna Wilieman, Isis H Trevenzoli, Lais C Agra, Johnatas D Silva, Christianne Bandeira-Melo, Pedro L Silva, Patricia R M Rocco, Tania M Ortiga-Carvalho
[This corrects the article on p. 828 in vol. 8, PMID: 29118715.].
2017: Frontiers in Physiology
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