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https://www.readbyqxmd.com/read/28938210/contribution-of-industrial-density-and-socioeconomic-status-to-the-spatial-distribution-of-thyroid-cancer-risk-in-hangzhou-china
#1
Xufeng Fei, Zhaohan Lou, George Christakos, Qingmin Liu, Yanjun Ren, Jiaping Wu
BACKGROUND: The thyroid cancer (TC) incidence in China has increased dramatically during the last three decades. Typical in this respect is the case of Hangzhou city (China), where 7147 new TC cases were diagnosed during the period 2008-2012. Hence, the assessment of the TC incidence risk increase due to environmental exposure is an important public health matter. METHODS: Correlation analysis, Analysis of Variance (ANOVA) and Poisson regression were first used to evaluate the statistical association between TC and key risk factors (industrial density and socioeconomic status)...
September 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28938204/natural-outdoor-environments-and-mental-health-stress-as-a-possible-mechanism
#2
Margarita Triguero-Mas, David Donaire-Gonzalez, Edmund Seto, Antònia Valentín, David Martínez, Graham Smith, Gemma Hurst, Glòria Carrasco-Turigas, Daniel Masterson, Magdalena van den Berg, Albert Ambròs, Tania Martínez-Íñiguez, Audrius Dedele, Naomi Ellis, Tomas Grazulevicius, Martin Voorsmit, Marta Cirach, Judith Cirac-Claveras, Wim Swart, Eddy Clasquin, Annemarie Ruijsbroek, Jolanda Maas, Michael Jerret, Regina Gražulevičienė, Hanneke Kruize, Christopher J Gidlow, Mark J Nieuwenhuijsen
INTRODUCTION: Better mental health has been associated with exposure to natural outdoor environments (NOE). However, comprehensive studies including several indicators of exposure and outcomes, potential effect modifiers and mediators are scarce. OBJECTIVES: We used novel, objective measures to explore the relationships between exposure to NOE (i.e. residential availability and contact) and different indicators of mental health, and possible modifiers and mediators...
September 19, 2017: Environmental Research
https://www.readbyqxmd.com/read/28938133/genetic-polymorphisms-for-19-x-str-loci-of-sichuan-han-ethnicity-and-its-comparison-with-chinese-populations
#3
Guanglin He, Ye Li, Xing Zou, Mengge Wang, Pengyu Chen, Miao Liao, Jin Wu
X-chromosomal short tandem repeats (X-STRs) can be serviced as a complementary tool in forensic deficiency cases and other complicated kinship identification. To investigate the genetic variation of the western Chinese Han population, genetic polymorphisms of 19 X-STR loci (DXS8378, DXS7423, DXS10148, DXS10159, DXS10134, DXS7424, DXS10164, DXS10162, DXS7132, DXS10079, DXS6789, DXS101, DXS10103, DXS10101, HPRTB, DXS6809, DXS10075, DXS10074 and DXS10135) included in the AGCU X19 PCR amplification kit were obtained from 201 Chinese Han individuals (108 females and 93 males) residing in Sichuan province, western China...
September 15, 2017: Legal Medicine
https://www.readbyqxmd.com/read/28938018/genome-wide-identification-of-bacterial-plant-colonization-genes
#4
Benjamin J Cole, Meghan E Feltcher, Robert J Waters, Kelly M Wetmore, Tatiana S Mucyn, Elizabeth M Ryan, Gaoyan Wang, Sabah Ul-Hasan, Meredith McDonald, Yasuo Yoshikuni, Rex R Malmstrom, Adam M Deutschbauer, Jeffery L Dangl, Axel Visel
Diverse soil-resident bacteria can contribute to plant growth and health, but the molecular mechanisms enabling them to effectively colonize their plant hosts remain poorly understood. We used randomly barcoded transposon mutagenesis sequencing (RB-TnSeq) in Pseudomonas simiae, a model root-colonizing bacterium, to establish a genome-wide map of bacterial genes required for colonization of the Arabidopsis thaliana root system. We identified 115 genes (2% of all P. simiae genes) with functions that are required for maximal competitive colonization of the root system...
September 22, 2017: PLoS Biology
https://www.readbyqxmd.com/read/28937846/polybrominated-diphenyl-ethers-pbdes-in-floor-and-road-dust-from-a-manual-e-waste-dismantling-facility-and-adjacent-communities-in-thailand
#5
Dudsadee Muenhor, Hyo-Bang Moon, Sunggyu Lee, Emma Goosey
This study characterizes concentrations of polybrominated diphenyl ethers (PBDEs) in floor and road dust from a manual e-waste dismantling facility and adjacent communities in Thailand. Levels of Σ22 PBDEs in floor dust from the facility varied between 1,200 and 43,000 ng g(-1), whereas those from adjacent communities were in the range 6.6-2,200 ng g(-1). Concentrations of Σ22 PBDEs (43,000 ng g(-1)) were highest in floor dust collected from the facility. Levels of Σ22 PBDEs and all congeners studied, except for BDE-66, BDE-71, BDE-85, BDE-119, BDE-138, BDE-190 and BDE-191 in facility dust were significantly greater than those in residential dust (P = <0...
September 22, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/28937617/comparison-of-patterns-of-use-of-unrecorded-and-recorded-spirits-survey-of-adult-drinkers-in-rural-central-china
#6
Shiqing Wei, Ping Yin, Ian M Newman, Ling Qian, Duane F Shell, Lok-Wa Yuen
About 70% of the beverage alcohol consumed in China annually is spirits. Recorded spirits make up most spirit consumption, but about 25% of total alcohol consumption (1.7 L pure alcohol per capita annually) is unrecorded spirits (bai jiu), either homemade or made in unregulated distilleries. In some parts of China, the consumption of unrecorded spirits is higher than average. This paper compares the patterns of use of unrecorded distilled spirits and recorded distilled spirits among rural residents in Central China...
September 22, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28937553/perinatal-and-maternal-outcomes-after-training-residents-in-forceps-before-vacuum-instrumental-birth
#7
Hans Peter Dietz, Ka Lai Shek, Sascha Callaghan
No abstract text is available yet for this article.
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28937517/effects-of-a-short-video-based-resident-as-teacher-training-toolkit-on-resident-teaching
#8
Hope A Ricciotti, Taylor S Freret, Ashley Aluko, Bri Anne McKeon, Miriam J Haviland, Lori R Newman
OBJECTIVE: To pilot a short video-based resident-as-teacher training toolkit and assess its effect on resident teaching skills in clinical settings. METHODS: A video-based resident-as-teacher training toolkit was previously developed by educational experts at Beth Israel Deaconess Medical Center, Harvard Medical School. Residents were recruited from two academic hospitals, watched two videos from the toolkit ("Clinical Teaching Skills" and "Effective Clinical Supervision"), and completed an accompanying self-study guide...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28937514/surgical-skills-feedback-and-mytipreport-is-there-construct-validity
#9
AnnaMarie Connolly, Anita Blanchard, Alice Goepfert, Nicole Donnellan, Elizabeth Buys, Richard Uribe, Kimberly Kenton
OBJECTIVE: To initiate construct validity testing of myTIPreport for procedural skill assessment in a prospective multicenter evaluation study. METHODS: Teachers and learners from a convenience-based site selection of obstetrics and gynecology (OBGYN) and female pelvic medicine and reconstructive surgery (FPMRS) training programs performed procedural assessments in myTIPreport. The specifically defined 5-point Dreyfus rating scale describing ability levels from novice to expert was used...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28937513/entrustment-evidence-used-by-expert-gynecologic-surgical-teachers-to-determine-residents-autonomy
#10
Xiaodong Phoenix Chen, Amy M Sullivan, Joan M Bengtson, John L Dalrymple
OBJECTIVE: To identify entrustment evidence used by expert gynecologic surgical teachers to determine obstetrics and gynecology residents' level of autonomy in the operating room. METHODS: A qualitative interview study was undertaken from March to November 2016. Four selection criteria were used to define and purposefully sample expert gynecologic surgical teachers across the United States to represent all four geographic regions. All interviews were audio-recorded and transcribed...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28937512/obstetricians-and-gynecologists-of-the-future-a-survey-of-medical-students-applying-to-residency
#11
Meredith J Alston, Amy Meg Autry, Sarah A Wagner, Abigail Winkel, Amanda A Allshouse, Alyssa Stephenson-Famy
OBJECTIVE: To understand the characteristics and career goals of medical students selecting a career in obstetrics and gynecology. METHODS: In 2015-2016, medical students invited for interviews for obstetrics and gynecology residency at the University of Colorado, University of Washington, University of California San Francisco, Loyola University, and New York University received a voluntary 20-item electronic survey regarding factors influencing their choice of medical specialty...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28937507/programme-directors-opinions-on-medical-genetics-education-in-pediatric-residency-programmes
#12
J Austin Hamm, Michele H Nichols, Nathaniel H Robin
No abstract text is available yet for this article.
September 20, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28937469/outcome-of-a-resident-spine-surgical-skills-training-program
#13
Brian P Calio, Christopher K Kepler, John D Koerner, Jeffrey A Rihn, Paul Millhouse, Kris E Radcliff
STUDY DESIGN: Cadaver training lab. OBJECTIVE: To determine if a technical cadaver skills training lab for spinal surgery increases resident confidence, satisfaction in training, and perception of operating room safety. SUMMARY OF BACKGROUND DATA: Resident training is an important topic in the setting of work hour reform. The use of supplemental materials such as videos, sawbones, and simulators may become important to adequately train orthopedic residents...
October 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28937191/ras-acs-symposium-essays-residents-debate-the-boundaries-of-surgeon-disclosure
#14
William H Ward
No abstract text is available yet for this article.
November 2016: Bulletin of the American College of Surgeons
https://www.readbyqxmd.com/read/28937154/structural-basis-of-interstrand-cross-link-repair-by-o-6-alkylguanine-dna-alkyltransferase
#15
Alexey Y Denisov, Francis P McManus, Derek K O'Flaherty, Anne M Noronha, Christopher J Wilds
DNA interstrand cross-links (ICL) are among the most cytotoxic lesions found in biological systems. O(6)-Alkylguanine DNA alkyltransferases (AGTs) are capable of removing alkylation damage from the O(6)-atom of 2'-deoxyguanosine and the O(4)-atom of thymidine. Human AGT (hAGT) has demonstrated the ability to repair an interstrand cross-linked duplex where two O(6)-atoms of 2'-deoxyguanosine were tethered by a butylene (XLGG4) or heptylene (XLGG7) linkage. However, the analogous ICL between the O(4)-atoms of thymidine was found to evade repair...
September 22, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28937038/factors-related-to-ventricular-size-and-valvular-regurgitation-in-healthy-tibetans-in-lhasa
#16
Ying Yang, Yun-Dai Chen, Bin Feng, Zha-Xi-Duo Ji, Wei Mao, Guang Zhi
BACKGROUND: Lhasa is the main residence of Tibetans and one of the highest cities in the world. Its unique geography and ethnic population provide the chance to investigate the interactions among high altitude, ethnicity, and cardiac adaptation. Meanwhile, echocardiographic data about healthy Tibetans on a large scale are not available. This study aimed to analyze physiological factors related to ventricular size and valvular function in healthy Tibetans in Lhasa. METHODS: A representative sample of residents in Tibet was recruited using a multistage cluster random sampling method...
October 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28936740/therapeutic-effects-of-mesenchymal-stem-cell-derived-exosomes-in-cardiovascular-disease
#17
Etsu Suzuki, Daishi Fujita, Masao Takahashi, Shigeyoshi Oba, Hiroaki Nishimatsu
Mesenchymal stem cells (MSCs) are multipotent stem cells that reside in various organs. They have the capacity to differentiate into various cell types, including cardiomyocytes, vascular endothelial cells, and vascular smooth muscle cells. Among the various MSCs, bone marrow-derived MSCs (BMMSCs) have been widely used for treating acute myocardial infarction (AMI) and ischemic heart failure (IHF) in preclinical and clinical studies. Although the beneficial effects of BMMSCs in treating AMI and IHF were originally attributed to their capacity to differentiate into cardiac cell types, recent evidence suggests that the differentiation capacity of BMMSCs appears to be minimal and that BMMSCs exert cardioprotective effects by secreting paracrine factors...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28936562/can-a-laparoscopic-roux-en-y-gastric-bypass-be-safely-performed-by-surgical-residents-in-a-bariatric-center-of-excellence-the-learning-curve-of-surgical-residents-in-bariatric-surgery
#18
Anne-Sophie van Rijswijk, Daan E Moes, Noëlle Geubbels, Barbara A Hutten, Yair I Z Acherman, Arnold W van de Laar, Maurits de Brauw, Sjoerd C Bruin
BACKGROUND: A learning curve (LC) is a graphic display of the number of consecutive procedures performed necessary to reach competence and is defined by complications and duration of surgery (DOS). There is little evidence on the LC of surgical residents in bariatric surgery. Aim of the study is to evaluate whether the laparoscopic Roux-en-Y gastric bypass (LRYGB) can be safely performed by surgical residents, to evaluate the LC of surgical residents for LRYGB and to assess whether surgical residents fit in the LC of the bariatric center which has been established by their proctors...
September 21, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28936545/open-tracheostomy-training-a-nationwide-survey-among-otolaryngology-head-and-neck-surgery-residents
#19
Limor Muallem-Kalmovich, Jacob Pitaro, Ayman Asaly, Alex Kessler, Ephraim Eviatar, Moran Shteiner, Tal Marom
The aim of this study was to examine the training methods and needs of Otolaryngology-Head and Neck Surgery (OTO-HNS) residents to independently perform open tracheostomy (OT). An anonymous 26-items questionnaire pertaining to OT teaching aspects was distributed to all 93 Israeli OTO-HNS residents during March-June 2016. Residents were categorized as 'juniors,' if they were in their post-graduate year (PGY)-1 and PGY-2; 'mid-residency' (PGY-3 and PGY-4); or 'seniors' (PGY-5 and PGY-6). Response rate was 74% (n = 69)...
September 21, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28936535/8-oxo-7-8-dihydro-2-deoxyguanosine-and-abasic-site-tandem-lesions-are-oxidation-prone-yielding-hydantoin-products-that-strongly-destabilize-duplex-dna
#20
Aaron M Fleming, Cynthia J Burrows
In DNA, 2'-deoxyguanosine (dG) is susceptible to oxidative modification by reactive oxygen species (ROS) yielding many products, one of which is 8-oxo-7,8-dihydro-2'-deoxyguanosine (dOG). Interestingly, dOG is stable but much more labile toward oxidation than dG, furnishing 5-guanidinohydantoin-2'-deoxyribose (dGh) that is favored in the duplex context or spiroiminodihydantoin-2'-deoxyribose (dSp) that is favored in the oxidation of single-stranded contexts. Previously, exposure of DNA to ionizing radiation found ∼50% of the dOG exists as a tandem lesion with an adjacent formamide site...
September 22, 2017: Organic & Biomolecular Chemistry
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