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Blood transfusion orthopedic

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https://www.readbyqxmd.com/read/27871515/perioperative-antiplatelet-therapy-and-cardiovascular-outcomes-in-patients-undergoing-joint-and-spine-surgery
#1
Nathaniel R Smilowitz, Brandon S Oberweis, Swetha Nukala, Andrew Rosenberg, Steven Stuchin, Richard Iorio, Thomas Errico, Martha J Radford, Jeffrey S Berger
STUDY OBJECTIVE: Perioperative thrombotic complications after orthopedic surgery are associated with significant morbidity and mortality. The use of aspirin to reduce perioperative cardiovascular complications in certain high-risk cohorts remains controversial. Few studies have addressed aspirin use, bleeding, and cardiovascular outcomes among high-risk patients undergoing joint and spine surgery. DESIGN/SETTING/PATIENTS: We performed a retrospective comparison of adults undergoing knee, hip, or spine surgery at a tertiary care center during 2 periods between November 2008 and December 2009 (reference period) and between April 2013 and December 2013 (contemporary period)...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27783839/intraoperative-hypothermia-in-total-hip-and-knee-arthroplasty
#2
Nicholas B Frisch, Andrew M Pepper, Edward Rooney, Craig Silverton
Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are common and successful orthopedic procedures, and as their frequency continues to increase substantially, the focus on limiting perioperative complications heightens. Intraoperative normothermia is recommended to minimize additional complications, but limited evidence exists regarding the effect of hypothermia on orthopedic patients. The purpose of this retrospective study was to determine the incidence of perioperative hypothermia in the setting of TKA and THA, and to evaluate its impact on complications and outcomes...
October 25, 2016: Orthopedics
https://www.readbyqxmd.com/read/27779977/anticipated-transfusion-requirements-and-mortality-in-patients-with-orthopedic-and-solid-organ-injuries
#3
Devon S Callahan, Zane Ashman, Dennis Y Kim, David S Plurad
Long bone fractures are cited as an etiology for significant blood loss; however, there is scant supporting literature. We examined the relationship between long bone fractures, blood transfusions, and solid organ injuries. We hypothesize that transfusions are rare with long bone fractures in the absence of a liver or splenic injury. We performed a retrospective analysis of patients admitted with femur, tibia, and humerus fractures. Outcomes included transfusion requirements and mortality. A total of 1837 patients were included...
October 2016: American Surgeon
https://www.readbyqxmd.com/read/27761223/topical-versus-intravenous-administration-of-tranexamic-acid-in-primary-total-hip-arthroplasty-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#4
Sammy A Hanna, Anoop Prasad, Joshua Lee, Pramod Achan
Tranexamic acid (TA) is widely used by orthopedic surgeons to decrease blood loss and the need for transfusion following total hip arthroplasty (THA). Although both intravenous and topical applications are described in the literature, there remains no consensus regarding the optimal regimen, dosage and method of delivery of TA during THA. In addition, concerns still exist regarding the risk of thromboembolic events with intravenous administration. The purpose of this meta-analysis was to compare the efficacy and safety of topical versus intravenous administration of TA in THA...
September 19, 2016: Orthopedic Reviews
https://www.readbyqxmd.com/read/27732721/clinical-practice-guidelines-from-the-aabb-red-blood-cell-transfusion-thresholds-and-storage
#5
Jeffrey L Carson, Gordon Guyatt, Nancy M Heddle, Brenda J Grossman, Claudia S Cohn, Mark K Fung, Terry Gernsheimer, John B Holcomb, Lewis J Kaplan, Louis M Katz, Nikki Peterson, Glenn Ramsey, Sunil V Rao, John D Roback, Aryeh Shander, Aaron A R Tobian
Importance: More than 100 million units of blood are collected worldwide each year, yet the indication for red blood cell (RBC) transfusion and the optimal length of RBC storage prior to transfusion are uncertain. Objective: To provide recommendations for the target hemoglobin level for RBC transfusion among hospitalized adult patients who are hemodynamically stable and the length of time RBCs should be stored prior to transfusion. Evidence Review: Reference librarians conducted a literature search for randomized clinical trials (RCTs) evaluating hemoglobin thresholds for RBC transfusion (1950-May 2016) and RBC storage duration (1948-May 2016) without language restrictions...
November 15, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27716330/survival-rate-and-perioperative-data-of-patients-who-have-undergone-hemipelvectomy-a-retrospective-case-series
#6
Alfredo Guilherme Haack Couto, Bruno Araújo, Roberto André Torres de Vasconcelos, Marcos José Renni, Clóvis Orlando Da Fonseca, Ismar Lima Cavalcanti
BACKGROUND: Hemipelvectomy is a major orthopedic surgical procedure indicated in specific situations. Although many studies discuss surgical techniques for hemipelvectomy, few studies have presented survival data, especially in underdeveloped countries. Additionally, there is limited information on anesthesia for orthopedic oncologic surgeries. The primary aim of this study was to determine the survival rate after hemipelvectomy, and the secondary aims were to evaluate anesthesia and perioperative care associated with hemipelvectomy and determine the influence of the surgical technique (external hemipelvectomy [amputation] or internal hemipelvectomy [limb sparing surgery]) on anesthesia and perioperative care in Brazil...
October 7, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27703282/analysis-of-the-blood-consumption-for-surgical-programs
#7
Dzenana Begic, Ermina Mujicic, Jozo Coric, Svjetlana Loga Zec, Lejla Zunic
INTRODUCTION: Transfusion is an activity that assures sufficient supply of blood and blood components to treat the sick and injured. In transfusion departments is necessary to timely provide adequate amounts of blood and blood products for various surgical procedures. MATERIAL AND METHODS: To determine the total amount of preoperative requirements (BT/AB and BT/AB/MT) for blood and blood products in surgical departments of General Hospital "Prim. Dr. Abdulah Nakas" in the period from June 1, 2014 - December 31, 2014 and analyze the requirements for blood in relation to surgical procedures, surgical discipline, period, age and gender of patients...
July 27, 2016: Medical Archives
https://www.readbyqxmd.com/read/27682006/allogeneic-blood-transfusion-is-a-significant-risk-factor-for-surgical-site-infection-following-total-hip-and-knee-arthroplasty-a-meta-analysis
#8
Jeong Lae Kim, Jong-Hoon Park, Seung-Beom Han, Il Youp Cho, Ki-Mo Jang
BACKGROUND: Blood loss occurs significantly more frequently during total hip and knee arthroplasty than among any other type of orthopedic operation, which can sometimes lead to requiring a blood transfusion. Although allogeneic blood transfusion has been identified as a risk factor for postoperative surgical-site infection following arthroplasty, results are inconclusive. The purpose of this study was to conduct a systematic meta-analysis to investigate whether having an allogeneic blood transfusion significantly increases the risk for surgical-site infection, particularly after total hip and knee arthroplasty...
August 31, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27671768/risk-factors-for-30-day-postoperative-complications-following-open-reduction-internal-fixation-of-proximal%C3%A2-ulna-fractures
#9
Nikunj N Trivedi, Matthew R Cohn, Samir K Trehan, Aaron Daluiski
PURPOSE: Fractures of the proximal ulna are common injuries in the elderly population. These fractures can be managed nonsurgically or with open reduction internal fixation (ORIF). Whereas nonsurgical management may lead to a relative loss of elbow extension and to nonunion, ORIF carries a risk of complications. Although complications specific to the orthopedic intervention have been reported, few studies have identified postoperative systemic complications in this higher-risk group. The purposes of this study were to determine the rate of systemic complications in patients undergoing surgical fixation of proximal ulna fractures and to determine risk factors for complications...
September 23, 2016: Journal of Hand Surgery
https://www.readbyqxmd.com/read/27670536/association-between-blood-transfusion-transfusion-setting-and-the-risk-of-venous-thromboembolism-in-patients-with-isolated-orthopedic-trauma
#10
Kevin J McGurk, Bryan R Collier, Eric H Bradburn, Katie M Love, Daniel I Lollar, Christopher C Baker, Mark E Hamill
No abstract text is available yet for this article.
September 2016: American Surgeon
https://www.readbyqxmd.com/read/27585725/effects-of-positive-suggestions-on-the-need-for-red-blood-cell-transfusion-in-orthopedic-surgery
#11
Csenge Szeverényi, Zoltán Csernátony, Ágnes Balogh, Tünde Simon, Katalin Varga
This study examined whether positive suggestions applied without a hypnotic induction in the perioperative period reduces the need for red blood cell transfusions in patients who underwent total hip or knee arthroplasties with spinal anesthesia. No hypnotic assessment was performed. Ninety-five patients were randomly assigned to the suggestion group (n = 45) and to the control group (n = 50). Patients in the suggestion group received verbal suggestions before and audiotaped suggestions during the surgery for reducing blood loss, anxiety, postoperative pain, and fast recovery...
October 2016: International Journal of Clinical and Experimental Hypnosis
https://www.readbyqxmd.com/read/27575038/factors-that-predict-blood-loss-after-bernese-periacetabular-osteotomy
#12
Eduardo N Novais, Patrick M Carry, Lauryn A Kestel, Jason Koerner, Gee Mei Tan
Although strategies to reduce bleeding and avoid allogeneic transfusion have been described, there is controversy about the factors associated with blood loss after Bernese periacetabular osteotomy. This study was conducted to determine risk factors for postoperative blood loss. After institutional review board approval was obtained, a retrospective review was conducted of 41 young patients who underwent periacetabular osteotomy for symptomatic acetabular dysplasia over a 3-year period. Of these patients, two-thirds donated blood before surgery...
November 1, 2016: Orthopedics
https://www.readbyqxmd.com/read/27536627/patient-blood-management-in-hip-replacement-arthroplasty
#13
REVIEW
Jong Hee Lee, Seung Beom Han
Perioperative blood transfusions are common in total hip arthroplasty because of preoperative anemia and perioperative blood loss. Perioperative anemia and the need for allogeneic blood transfusion are related with increased morbidity. To reduce perioperative allogeneic blood transfusion, keeping the preoperative hemoglobin level above 12.0 g/dL is important in orthopedic patients. By using the anti-fibrinolytic agent or perioperative cell salvage, reduce intraoperative blood loss is very important for the reduction of perioperative blood loss...
December 2015: Hip & Pelvis
https://www.readbyqxmd.com/read/27501656/tranexamic-acid-in-anesthetic-management-of-surgical-procedures
#14
Jessica Mayeux, Kathy Alwon, Shawn Collins, Ian Hewer
Blood loss during surgical procedures poses a grave risk to the patient, but transfusion is costly and associated with adverse outcomes. Antifibrinolytics, however, offer an economical and effective means of decreasing blood loss associated with surgical procedures. Tranexamic acid (TXA) is an antifibrinolytic that blocks lysine-binding sites of fibrinogen and fibrin, preventing the breakdown of existing clots. This journal course reviews extensive research demonstrating that antifibrinolytics such as TXA decrease blood loss and in some studies reduce allogeneic transfusion requirements...
June 2016: AANA Journal
https://www.readbyqxmd.com/read/27443498/patient-reported-and-radiographic-outcomes-of-minimally-invasive-transforaminal-lumbar-interbody-fusion-for-degenerative-spondylolisthesis-with-or-without-reduction-a-comparative-study
#15
Guoxin Fan, Hailong Zhang, Xiaofei Guan, Guangfei Gu, Xinbo Wu, Annan Hu, Xin Gu, Shisheng He
This retrospective study aimed to compare the patient-reported outcomes and radiographic assessment of minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) for degenerative spondylolisthesis with reduction versus in situ fusion. Patients receiving MI-TLIF with reduction were assigned as Group A, and those without reduction were assigned as Group B. Radiographic fusion was assessed using Bridwell's grading criteria. Preoperative and postoperative patient-reported outcomes including visual analogue score (VAS), Oswestry Disability Index (ODI), Japanese Orthopedic Association (JOA) scale and improvement rate were analyzed...
November 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27353059/associated-injuries-in-skeletally-immature-children-with-pelvic-fractures
#16
M Kareem Shaath, Kenneth L Koury, Peter D Gibson, Mark R Adams, Michael S Sirkin, Mark C Reilly
BACKGROUND: Pediatric pelvic fractures are rare injuries resulting from high-energy mechanisms that warrant an extensive work-up for associated injuries. OBJECTIVES: We performed a retrospective study to review concomitant injuries in children who suffered a pelvic fracture and have an open triradiate cartilage. METHODS: Using a database, pediatric pelvic fractures presenting to the authors' institution were extracted. Radiographs and computed tomography scans were reviewed, ensuring that triradiate cartilages were not fused and the pelvic injuries were classified using the Modified Torode Classification...
September 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27286051/effects-of-tourniquet-release-on-total-knee-arthroplasty
#17
Kai Tie, Dongcai Hu, Yongjian Qi, Hua Wang, Liaobin Chen
This study investigated the clinical outcomes of early and late tourniquet release (tourniquet release after cementing the prosthesis vs tourniquet release after wound closure and pressure dressing) in total knee arthroplasty (TKA). The study was conducted by searching PubMed, Embase, Web of Science, and Cochrane Central databases for articles on randomized controlled trials comparing early and late tourniquet release in primary TKA that were published from 1966 to March 2015. Relevant data were extracted, and the Physiotherapy Evidence Database (PEDro) Scale was used to assess the methodologic quality...
July 1, 2016: Orthopedics
https://www.readbyqxmd.com/read/27251666/blood-transfusion-strategy-and-risk-of-postoperative-delirium-in-nursing-homes-residents-with-hip-fracture-a-post-hoc-analysis-based-on-the-trife-randomized-controlled-trial
#18
Sif Blandfort, Merete Gregersen, Lars Carl Borris, Else Marie Damsgaard
OBJECTIVES: To investigate whether a liberal blood transfusion strategy [Hb levels ≥11.3 g/dL (7 mmol/L)] reduces the risk of postoperative delirium (POD) on day 10, among nursing home residents with hip fracture, compared to a restrictive transfusion strategy [Hb levels ≥9.7 g/dL (6 mmol/L)]. Furthermore, to investigate whether POD influences mortality within 90 days after hip surgery. METHODS: This is a post hoc analysis based on The TRIFE - a randomized controlled trial...
June 1, 2016: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27248332/meta-analysis-of-intravenous-tranexamic-acid-in-primary-total-hip-arthroplasty
#19
Joseph T Moskal, Susan G Capps
Previous meta-analyses established that tranexamic acid confers benefits when used during total hip arthroplasty (THA). However, 2 of these meta-analyses included a variety of routes of administration of tranexamic acid in THA (topical, intravenous, oral, and intra-articular), another meta-analysis included a variety of antifibrinolytic drugs (not restricted to a single drug), and the final meta-analysis included nonrandomized controlled trials. This meta-analysis focused on a single medication, tranexamic acid, administered in a specific way, intravenously in patients undergoing primary THA, using data reported only in randomized controlled studies...
September 1, 2016: Orthopedics
https://www.readbyqxmd.com/read/27172370/effect-of-body-mass-index-on-blood-transfusion-in-total-hip-and-knee-arthroplasty
#20
Nicholas Frisch, Nolan M Wessell, Michael Charters, Ed Peterson, Brett Cann, Alex Greenstein, Craig D Silverton
Perioperative blood management remains a challenge during total hip arthroplasty (THA) and total knee arthroplasty (TKA). The purpose of this study was to systematically examine the relationship between body mass index (BMI) and perioperative blood transfusion during THA and TKA while attempting to resolve conflicting results in previously published studies. The authors retrospectively evaluated 2399 patients, 896 of whom underwent THA and 1503 of whom underwent TKA. Various outcome variables were assessed for their relationship to BMI, which was stratified using the World Health Organization classification scheme (normal, <25 kg/m(2); overweight, 25-30 kg/m(2); obese, >30 kg/m(2))...
September 1, 2016: Orthopedics
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