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Yahui Sun, Yun Huang, Qiang Liao, Ao Xia, Qian Fu, Xun Zhu, Jingwei Fu
Aiming at alleviating the adverse effect of poor light penetrability on microalgae growth, planar waveguide modules functioned as diluting and redistributing the intense incident light within microalgae culture more homogeneously were introduced into a lab-scale open raceway pond (ORP) for Nannochloropsis oculata cultivation. As compared to the conventional ORP, the illumination surface area to volume ratio and effective illuminated volume percentage in the proposed ORP were respectively improved by 5.53 times and 19...
November 6, 2017: Bioresource Technology
Ashok Agarwal, Albert Danh Bui
Male infertility affects men worldwide. Oxidative stress (OS), characterized by an overabundance of reactive oxygen species (ROS) or a deficiency of antioxidants, is one of the major causes of male infertility. OS causes damage at the molecular level, which impairs lipids, proteins, and DNA. The cyclic cascade of redox reactions weakens sperm function which leads to poor semen parameters and eventual sterility. There is a need for advanced diagnostic tests that can quickly and accurately detect OS. Most commonly used assays can only measure single constituents of OS...
November 2017: Investigative and Clinical Urology
Milos Opacic, Zorica Stevic, Vladimir Bascarevic, Miroslav Zivic, Mihajlo Spasic, Ivan Spasojevic
The monitoring of progression in amyotrophic lateral sclerosis (ALS) relies on clinical outcome measures that take months to interpret, such as revised ALS functional rating scale (ALSFRS-R) score, with no approved biomarkers. A number of clinical studies have documented the involvement of oxidative stress in ALS pathology. Pertinent to this, we propose to evaluate oxidation-reduction potential (ORP) of cerebrospinal fluid (CSF) as a potential indicator of ALS progression. The case/control study included 24 patients with neurological non-neurodegenerative disorders (controls), and 82 ALS patients with different degrees of disease (ALSFRS-R score: 21-47)...
November 7, 2017: Antioxidants & Redox Signaling
Zheqin Dai, Xiwu Lu, Zhaoqian Jing
The Alternate multiple tanks (AMT) system was originated by Southeast University to meet pressing requirements of new highly-compact sewage treatment with cost-effective balance and automated management. DO and ORP as economic monitoring indicators are closely linked to nutrients variations and controlling strategy. Thus this paper was to investigate the N and P periodic variations and removal mechanisms under different aeration strengths in scope of principal-type tank in AMT, and the relationship between nutrients and DO, ORP...
November 3, 2017: Environmental Technology
Amy E Schmidt, Emily Gore, Kelly F Henrichs, Grace Conley, Charles Dorsey, Kimberly B Bjugstad, Majed A Refaai, Neil Blumberg, Jill M Cholette
Oxidation reduction potential (ORP) or Redox is the ratio of activity between oxidizers and reducers. Oxidative stress (OS) can cause cellular injury and death, and is important in the regulation of immune response to injury or disease. In the present study, we investigated changes in the redox system as a function of cardiopulmonary bypass (CPB) in pediatric patients. 664 plasma samples were collected from 162 pediatric patients having cardiac surgery of various CPB times. Lower ORP values at 12 h post-CPB were associated with poor survival rate (mean ± SD 167 ± 20 vs...
October 31, 2017: Pediatric Cardiology
Ke Wang, Hailong Mao, Xiangkun Li
The metabolic function of microbial community dominated organics and nutrients transformation in aerobic composting process. In this study, the metabolic characteristics of bacterial and fungal communities were evaluated in 60 days composting of sludge and pumice by using FUNGuild and PICRUSt, respectively. The results showed that microbial community structure and metabolic characteristics were distinctively different at four composting periods. Bacterial genes related to carbohydrate metabolisms decreased during the first 30 days, but bacterial sequences associated with oxidative phosphorylation and fatty acids synthesis were enhanced in curing phase...
October 10, 2017: Bioresource Technology
Dragan Ilic, Sue M Evans, Christie Ann Allan, Jae Hung Jung, Declan Murphy, Mark Frydenberg
To determine the effects of laparoscopic radical prostatectomy (LRP), or robotic-assisted radical prostatectomy (RARP), compared to open radical prostatectomy (ORP) in men with localised prostate cancer. We performed a comprehensive search using multiple databases (CENTRAL, MEDLINE, EMBASE) and abstract proceedings with no restrictions on the language of publication or publication status, up until 9 June 2017. We included all randomised or pseudo-randomised controlled trials with a direct comparison of LRP and RARP to ORP...
October 24, 2017: BJU International
A Agarwal, R Henkel, R Sharma, N N Tadros, E Sabanegh
Oxidative stress (OS) is an important contributing factor to male infertility. While previous methods to measure seminal OS are time-consuming and limited to the use of freshly produced semen, oxidation reduction potential (ORP) is easier and quicker to perform and can also be used in frozen semen. Therefore, this study evaluated the clinical utility of ORP as a potential marker of male infertility. ORP was measured in semen samples from 293 patients and 15 fertile controls and categorised according to WHO criteria as normozoospermic, oligozoospermic, asthenozoospermic, teratozoospermic and oligoasthenoteratozoospermic...
October 23, 2017: Andrologia
Christoph Schwarz, Fabian Fitschek, David Bar-Or, Daniel A Klaus, Bianca Tudor, Edith Fleischmann, Georg Roth, Dietmar Tamandl, Thomas Wekerle, Michael Gnant, Martin Bodingbauer, Klaus Kaczirek
BACKGROUND: Postoperative complications are still a major concern after liver resection (LR). Systemic inflammation and deregulated reactive oxygen species during major abdominal surgery may impair outcome after hepatectomy. METHODS: Patients undergoing LR were included in this study (n = 40). Oxidative stress (OS) was measured peri- and post-operatively as static oxidation-reduction potential markers (sORP) and antioxidant capacity ORP (cORP) by using the RedoxSYS Diagnostic system...
2017: PloS One
Grace M Nisola, Kris Niño G Valdehuesa, Alex V Anonas, Kristine Rose M Ramos, Won-Keun Lee, Wook-Jin Chung
The feasibility of open-pore polyurethane (PU) foam as packing material for wet chemical scrubber was tested for NH3 and H2S removals. The foam is inexpensive, light-weight, highly porous (low pressure drop) and provides large surface area per unit volume, which are desirable properties for enhanced gas/liquid mass transfer. Conventional HCl/HOCl (for NH3) and NaOH/NaOCl (for H2S) scrubbing solutions were used to absorb and oxidize the gases. Assessment of the wet chemical scrubbers reveals that pH and ORP levels are important to maintain the gas removal efficiencies >95%...
October 16, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
A Sujenthiran, J Nossiter, M Parry, S C Charman, A Aggarwal, H Payne, P Dasgupta, N W Clarke, J van der Meulen, P Cathcart
OBJECTIVES: Despite the rapid adoption of robot-assisted radical prostatectomy (RARP), there is little evidence about the occurrence of medium-term urinary complications with this type of surgery compared to laparoscopic (LRP) or retropubic open radical prostatectomy (ORP). The aim of this study was to evaluate the occurrence of severe urinary complications within two years of surgery in men undergoing RARP, LRP or ORP. PATIENTS AND METHODS: Population-based cohort study of men who underwent RARP (n=4,947), LRP (n= 5,479), or ORP (n=6,873) between 2008 and 2012 in the English National Health Service (NHS) using national cancer registry records linked to Hospital Episodes Statistics - an administrative database of admissions to NHS hospitals...
October 15, 2017: BJU International
Richard J Smindak, Lindsay A Heckle, Supraja S Chittari, Marissa A Hand, Dylan M Hyatt, Grace E Mantus, William A Sanfelippo, Keith G Kozminski
Polarized exocytosis is an essential process in many organisms and cell types for proper cell division or functional specialization. Previous studies established that Oxysterol Binding Protein (OSBP) homologues in S. cerevisiae, which comprise the Osh protein family, are necessary for efficient polarized exocytosis by supporting a late step post-Golgi. We define that step as the docking of a specific sub-population of exocytic vesicles with the plasma membrane. In the absence of other Osh proteins, Osh4p can support this process in a manner dependent upon two lipid ligands, PI4P and sterol...
October 9, 2017: Journal of Cell Science
Rajesh Ghai, Ximing Du, Huan Wang, Jiangqing Dong, Charles Ferguson, Andrew J Brown, Robert G Parton, Jia-Wei Wu, Hongyuan Yang
ORP5 and ORP8, members of the oxysterol-binding protein (OSBP)-related proteins (ORP) family, are endoplasmic reticulum membrane proteins implicated in lipid trafficking. ORP5 and ORP8 are reported to localize to endoplasmic reticulum-plasma membrane junctions via binding to phosphatidylinositol-4-phosphate (PtdIns(4)P), and act as a PtdIns(4)P/phosphatidylserine counter exchanger between the endoplasmic reticulum and plasma membrane. Here we provide evidence that the pleckstrin homology domain of ORP5/8 via PtdIns(4,5)P 2, and not PtdIns(4)P binding mediates the recruitment of ORP5/8 to endoplasmic reticulum-plasma membrane contact sites...
October 2, 2017: Nature Communications
Saikat Dutta, Sampurna Roychoudhary, Bijaya Ketan Sarangi
Natural indigo production from Indigofera plant biomass requires fermentation of biomass, oxidation of fermented broth, settling of oxidized product (indigo), filtration and recovery. In this study, we have investigated roles of physico-chemical parameters during fermentation with respect to product yield. The study showed that water-to-biomass ratio (1:10), fermentation duration (0, 6, 12, 18, 24 h), pH (6-7.5), dissolved oxygen concentration; DO (0.5-3 mg ml(-1)), oxidation reduction potential ORP (+50 to -300 mV) and temperature (25-40 °C) during fermentation, oxidation and dye recovery from the broth are directly or indirectly related to indigo yield...
October 2017: 3 Biotech
Hitomi Nakamura, Takayoshi Hosono, Keiichi Kumasawa, Tadashi Kimura
In current infertility treatments it is necessary to evaluate uterine receptivity in each menstrual cycle. During the implantation period, the uterus goes through many complex orchestrated changes, including changes to the glycocalyx. The changes to the glycocalyx are due to sialylation, sulfation and fucosylation. Can the measurement of in-vivo uterine pH and/or oxidation-reduction potential (ORP) determine the alterations of uterine endometrium for implantation and evaluate prospective uterine receptivity? In the present study we assessed in vivo uterine pH and ORP during the early stages of pregnancy in naïve mice, as well as in a murine model of implantation failure created by local and transient suppression of signal transducer and activator of transcription 3...
September 25, 2017: Reproduction, Fertility, and Development
Micòl Mastrocicco, Dario Di Giuseppe, Fabio Vincenzi, Nicolò Colombani, Giuseppe Castaldelli
In agricultural lowland landscapes, intensive agricultural is accompanied by a wide use of agrochemical application, like pesticides and fertilizers. The latter often causes serious environmental threats such as N compounds leaching and surface water eutrophication; additionally, since perchlorate can be present as impurities in many fertilizers, the potential presence of perchlorates and their by-products like chlorates and chlorites in shallow groundwater could be a reason of concern. In this light, the present manuscript reports the first temporal and spatial variation of chlorates, chlorites and major anions concentrations in the shallow unconfined aquifer belonging to Ferrara province (in the Po River plain)...
December 2017: Environmental Pollution
Dragan Ilic, Sue M Evans, Christie Ann Allan, Jae Hung Jung, Declan Murphy, Mark Frydenberg
BACKGROUND: Prostate cancer is commonly diagnosed in men worldwide. Surgery, in the form of radical prostatectomy, is one of the main forms of treatment for men with localised prostate cancer. Prostatectomy has traditionally been performed as open surgery, typically via a retropubic approach. The advent of laparoscopic approaches, including robotic-assisted, provides a minimally invasive alternative to open radical prostatectomy (ORP). OBJECTIVES: To assess the effects of laparoscopic radical prostatectomy or robotic-assisted radical prostatectomy compared to open radical prostatectomy in men with localised prostate cancer...
September 12, 2017: Cochrane Database of Systematic Reviews
Luca Boeri, Paolo Capogrosso, Eugenio Ventimiglia, Walter Cazzaniga, Filippo Pederzoli, Giorgio Gandaglia, Nadia Finocchio, Federico Dehò, Alberto Briganti, Emanuele Montanari, Francesco Montorsi, Andrea Salonia
PURPOSE: We assessed the rate and predictors of depressive symptoms and impaired sexual desire in patients who underwent open or robot-assisted radical prostatectomy. MATERIALS AND METHODS: A total of 811 patients completed IIEF (International Index of Erectile Function) and BDI (Beck Depression Inventory) preoperatively, and 6, 12, 24 and 36 months postoperatively. Rates and predictors of depressive symptoms and impaired sexual desire were assessed with descriptive statistics and logistic regression models...
September 1, 2017: Journal of Urology
Kimberly B Bjugstad, Jeffrey Lalama, Leonard T Rael, Kristin Salottolo, Ira Dauber, David Bar-Or
OBJECTIVES: In congestive heart failure (CHF), men are younger, more likely to have reduced ejection fraction (HF-rEF), and to be diabetic compared to women. Despite this, sex differences in oxidative stress have yet to be explored in CHF. METHODS: Data from 67 males and 63 females hospitalized for CHF were collected. Static oxidation-reduction potential (sORP), a relative indicator of oxidative stress, and capacity ORP (icORP), a relative indicator of antioxidant capacity, were measured from plasma samples...
August 28, 2017: Redox Report: Communications in Free Radical Research
R M S Thorn, J Pendred, D M Reynolds
The main aim of this study was to assess the antimicrobial efficacy of electrochemically activated fog (ECAF) for reducing the microbial bio-burden on artificially inoculated fresh produce held under cooled (cucumber and vine tomatoes) or cold (rocket and broccoli) storage conditions. The ECAF treatment (1100 ± 5 mV ORP; 50 ± 5 mg L(-1) free chlorine; 2.7 ± 0.1 pH) resulted in a significant log reduction in the potential pathogen E. coli recovered from rocket (2.644 Log10 CFU g(-1)), broccoli (4...
December 2017: Food Microbiology
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