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https://www.readbyqxmd.com/read/28941468/prospective-evaluation-of-uterine-receptivity-in-mice
#1
Hitomi Nakamura, Takayoshi Hosono, Keiichi Kumasawa, Tadashi Kimura
In current infertility treatments it is necessary to evaluate uterine receptivity in each menstrual cycle. During the implantation period, the uterus goes through many complex orchestrated changes, including changes to the glycocalyx. The changes to the glycocalyx are due to sialylation, sulfation and fucosylation. Can the measurement of in-vivo uterine pH and/or oxidation-reduction potential (ORP) determine the alterations of uterine endometrium for implantation and evaluate prospective uterine receptivity? In the present study we assessed in vivo uterine pH and ORP during the early stages of pregnancy in naïve mice, as well as in a murine model of implantation failure created by local and transient suppression of signal transducer and activator of transcription 3...
September 25, 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/28916282/chlorate-origin-and-fate-in-shallow-groundwater-below-agricultural-landscapes
#2
Micòl Mastrocicco, Dario Di Giuseppe, Fabio Vincenzi, Nicolò Colombani, Giuseppe Castaldelli
In agricultural lowland landscapes, intensive agricultural is accompanied by a wide use of agrochemical application, like pesticides and fertilizers. The latter often causes serious environmental threats such as N compounds leaching and surface water eutrophication; additionally, since perchlorate can be present as impurities in many fertilizers, the potential presence of perchlorates and their by-products like chlorates and chlorites in shallow groundwater could be a reason of concern. In this light, the present manuscript reports the first temporal and spatial variation of chlorates, chlorites and major anions concentrations in the shallow unconfined aquifer belonging to Ferrara province (in the Po River plain)...
September 12, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28895658/laparoscopic-and-robotic-assisted-versus-open-radical-prostatectomy-for-the-treatment-of-localised-prostate-cancer
#3
REVIEW
Dragan Ilic, Sue M Evans, Christie Ann Allan, Jae Hung Jung, Declan Murphy, Mark Frydenberg
BACKGROUND: Prostate cancer is commonly diagnosed in men worldwide. Surgery, in the form of radical prostatectomy, is one of the main forms of treatment for men with localised prostate cancer. Prostatectomy has traditionally been performed as open surgery, typically via a retropubic approach. The advent of laparoscopic approaches, including robotic-assisted, provides a minimally invasive alternative to open radical prostatectomy (ORP). OBJECTIVES: To assess the effects of laparoscopic radical prostatectomy or robotic-assisted radical prostatectomy compared to open radical prostatectomy in men with localised prostate cancer...
September 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28867561/depressive-symptoms-and-low-sexual-desire-after-radical-prostatectomy-early-and-long-term-outcomes-in-a-real-life-setting
#4
Luca Boeri, Paolo Capogrosso, Eugenio Ventimiglia, Walter Cazzaniga, Filippo Pederzoli, Giorgio Gandaglia, Nadia Finocchio, Federico Dehò, Alberto Briganti, Emanuele Montanari, Francesco Montorsi, Andrea Salonia
PURPOSE: To assess the rate of and predictors of depressive symptoms (DS) and sexual desire (SD) impairment in patients who underwent either open (ORP) or robot-assisted (RARP) radical prostatectomy. MATERIALS AND METHODS: 811 patients completed the International Index of Erectile Function (IIEF) and the Beck's Inventory for Depression (BDI) preoperatively and at 6, 12, 24 and 36 months post surgery. Rates and predictors of DS and SD impairment were assessed with descriptive statistics and logistic regression models...
August 31, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28845739/poor-acute-outcome-in-congestive-heart-failure-is-associated-with-increases-in-the-plasma-static-oxidation-reduction-potentials-sorp-in-men-but-not-in-women
#5
Kimberly B Bjugstad, Jeffrey Lalama, Leonard T Rael, Kristin Salottolo, Ira Dauber, David Bar-Or
OBJECTIVES: In congestive heart failure (CHF), men are younger, more likely to have reduced ejection fraction (HF-rEF), and to be diabetic compared to women. Despite this, sex differences in oxidative stress have yet to be explored in CHF. METHODS: Data from 67 males and 63 females hospitalized for CHF were collected. Static oxidation-reduction potential (sORP), a relative indicator of oxidative stress, and capacity ORP (icORP), a relative indicator of antioxidant capacity, were measured from plasma samples...
August 28, 2017: Redox Report: Communications in Free Radical Research
https://www.readbyqxmd.com/read/28800824/assessing-the-antimicrobial-potential-of-aerosolised-electrochemically-activated-solutions-ecas-for-reducing-the-microbial-bio-burden-on-fresh-food-produce-held-under-cooled-or-cold-storage-conditions
#6
R M S Thorn, J Pendred, D M Reynolds
The main aim of this study was to assess the antimicrobial efficacy of electrochemically activated fog (ECAF) for reducing the microbial bio-burden on artificially inoculated fresh produce held under cooled (cucumber and vine tomatoes) or cold (rocket and broccoli) storage conditions. The ECAF treatment (1100 ± 5 mV ORP; 50 ± 5 mg L(-1) free chlorine; 2.7 ± 0.1 pH) resulted in a significant log reduction in the potential pathogen E. coli recovered from rocket (2.644 Log10 CFU g(-1)), broccoli (4...
December 2017: Food Microbiology
https://www.readbyqxmd.com/read/28796497/effects-of-muscle-specific-oxidative-stress-on-cytochrome-c-release-and-oxidation-reduction-potential-properties
#7
Yiling Ke, Rachel M Mitacek, Anupam Abraham, Gretchen G Mafi, Deborah L VanOverbeke, Udaya DeSilva, Ranjith Ramanathan
Mitochondria play a significant role in beef color. However, the role of oxidative stress in cytochrome c release and mitochondrial degradation is not clear. The objective was to determine the effects of display time on cytochrome c content and oxidation-reduction potential (ORP) of beef longissimus lumborum (LL) and psoas major (PM) muscles. PM discolored by day 3 compared with LL. On day 0, mitochondrial content and mitochondrial oxygen consumption were greater in PM than LL. However, mitochondrial content and oxygen consumption were lower (P < 0...
September 6, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28791778/redox-properties-of-transitional-milk-from-mothers-of-preterm-infants
#8
Simeon Minić, Miloš Ješić, Dijana Đurović, Srdjan Miletić, Nikoleta Lugonja, Vesna Marinković, Aleksandra Nikolić-Kokić, Snežana Spasić, Miroslav M Vrvić
AIM: There is a discrepancy between the amount of transitional milk produced by mothers of preterm infants and the low capacity of premature infants to consume it. This milk can be used in milk banks, but previous studies found that there are large variations in the level of host-defence proteins in individual samples of milk from mothers of premature infants, which implies that large individual variations in antioxidative defence composition are also possible. METHODS: Milk samples were collected from 20 healthy mothers of preterm infants...
August 9, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28780357/impact-of-macrozoobenthic-bioturbation-and-wind-fluctuation-interactions-on-net-methylmercury-in-freshwater-lakes
#9
Peifang Wang, Yu Yao, Chao Wang, Jun Hou, Jin Qian, Lingzhan Miao
The methylmercury (MeHg) as the toxic fractions has presented significant threats to biota in freshwater ecosystems. Hg methylation process is demonstrated to be manipulated by biota process (benthic disturbance and algae bloom existence) as well as the abiotic influence (wind fluctuation and illumination intensity) in freshwater ecosystems. However, the mechanisms influencing Hg methylation are still unclear, and the coupled influences of the biotic and abiotic process with the shifts in variation on methylmercury remain unexplored...
July 31, 2017: Water Research
https://www.readbyqxmd.com/read/28753913/multifunctional-water-sensors-for-ph-orp-and-conductivity-using-only-microfabricated-platinum-electrodes
#10
Wen-Chi Lin, Klaus Brondum, Charles W Monroe, Mark A Burns
Monitoring of the pH, oxidation-reduction-potential (ORP), and conductivity of aqueous samples is typically performed using multiple sensors. To minimize the size and cost of these sensors for practical applications, we have investigated the use of a single sensor constructed with only bare platinum electrodes deposited on a glass substrate. The sensor can measure pH from 4 to 10 while simultaneously measuring ORP from 150 to 800 mV. The device can also measure conductivity up to 8000 μS/cm in the range of 10 °C to 50 °C, and all these measurements can be made even if the water samples contain common ions found in residential water...
July 19, 2017: Sensors
https://www.readbyqxmd.com/read/28742344/insights-into-the-molybdenum-copper-heterometallic-cluster-assembly-in-the-orange-protein-probing-intermolecular-interactions-with-an-artificial-metal-binding-atcun-tag
#11
Biplab K Maiti, Rui M Almeida, Luisa B Maia, Isabel Moura, José J G Moura
Orange protein (ORP) is a small bacterial protein, of unknown function, that contains a unique molybdenum/copper heterometallic cluster, [S2Mo(VI)S2Cu(I)S2Mo(VI)S2](3-) (Mo/Cu), non-covalently bound. The native cluster can be reconstituted in a protein-assisted mode by the addition of Cu(II) plus tetrathiomolybdate to apo-ORP under controlled conditions. In the work described herein, we artificially inserted the ATCUN ("amino terminus Cu and Ni") motif in the Desulfovibrio gigas ORP (Ala1Ser2His3 followed by the native amino acid residues; modified protein abbreviated as ORP*) to increase our understanding of the Mo/Cu cluster assembly in ORP...
August 7, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28740247/inactivation-mechanism-of-escherichia-coli-induced-by-slightly-acidic-electrolyzed-water
#12
Zhangying Ye, Shuo Wang, Tao Chen, Weishan Gao, Songming Zhu, Jinsong He, Zhiying Han
Foodborne disease outbreak caused by food microbiological contamination is a serious public health problem. Slightly acidic electrolyzed water (SAEW), a new ultra-high effect and wide-spectrum disinfectant that is colourless, odourless, and harmless to humans and the environment, is directly used on food surfaces in Japan and America. However, the underlying inactivation mechanism remains unknown. In this study, biochemical and cellular changes were observed to investigate the bactericidal mechanism of SAEW against Escherichia coli (E...
July 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28733164/the-role-of-oxysterol-binding-protein-and-its-related-proteins-in-cancer
#13
REVIEW
Ximing Du, Nigel Turner, Hongyuan Yang
Oxysterol-binding protein (OSBP) and its related proteins (ORPs) constitute a large, evolutionarily conserved family of lipid-binding proteins that are associated with a wide range of cellular activities. The core function of OSBP/ORPs appears to be moving lipids between cellular membranes in a non-vesicular manner. Recent studies have unveiled a novel, counter-transport mechanism of cellular lipid transfer mediated by OSBP/ORPs at the membrane contact sites that involves phosphatidylinositol 4-phosphate. Importantly, the OSBP/ORPs family has also been implicated in cell signalling pathways and cancer development...
July 18, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/28731563/improving-fructose-utilization-and-butanol-production-by-clostridium-acetobutylicum-via-extracellular-redox-potential-regulation-and-intracellular-metabolite-analysis
#14
Li-Jie Chen, You-Duo Wu, Chuang Xue, Feng-Wu Bai
Jerusalem artichoke (JA) can grow well in marginal lands with high biomass yield, and thus is a potential energy crop for biorefinery. The major biomass of JA is from tubers, which contain inulin that can be easily hydrolyzed into a mixture of fructose and glucose, but fructose utilization for producing butanol as an advanced biofuel is poor compared to glucose-based ABE fermentation by Clostridium acetobutylicum. In this article, the impact of extracellular redox potential (ORP) on the process was studied using a mixture of fructose and glucose to simulate the hydrolysate of JA tubers...
July 21, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28728109/zero-valent-aluminum-for-reductive-removal-of-aqueous-pollutants-over-a-wide-ph-range-performance-and-mechanism-especially-at-near-neutral-ph
#15
Shiying Yang, Di Zheng, Tengfei Ren, Yixuan Zhang, Jia Xin
Zero-valent aluminum (ZVAl) draws much attention due to its strong reducibility. However, under neutral pH conditions, the reduction ability of ZVAl for pollutant removal has still been suspected because of the formed compact surface film of Al-(hydr)oxide. In this study, unmodified ZVAl was employed to reductively remove aqueous pollutants over a wide pH range, and its performance and mechanism, especially at near-neutral pH, were systematically studied for the first time. Results demonstrated that ZVAl had a wide range of pH applicability from 2 to 12, even in neutral environment...
July 6, 2017: Water Research
https://www.readbyqxmd.com/read/28726302/a-multicenter-study-to-evaluate-oxidative-stress-by-oxidation-reduction-potential-a-reliable-and-reproducible-method
#16
A Agarwal, M Arafa, R Chandrakumar, A Majzoub, S AlSaid, H Elbardisi
Seminal oxidative stress (OS) is well-known to affect male fertility status. The discrepancy in OS measurement has hindered its clinical use as a quality indicator for semen. Some tests measured single markers of oxidants or reductants, leading to lack of standardization of results. Oxidation-reduction potential (ORP) is a better representative for OS as it provides an overall measure of the activity of both oxidants and reductants. ORP assessment by MiOXSYS has been introduced as a measure of OS with high specificity in differentiating fertile from infertile semen samples...
July 20, 2017: Andrology
https://www.readbyqxmd.com/read/28712032/copper-stressed-anaerobic-fermentation-biogas-properties-process-stability-biodegradation-and-enzyme-responses
#17
He Hao, Yonglan Tian, Huayong Zhang, Yang Chai
The effect of copper (added as CuCl2) on the anaerobic co-digestion of Phragmites straw and cow dung was studied in pilot experiments by investigating the biogas properties, process stability, substrate degradation and enzyme activities at different stages of mesophilic fermentation. The results showed that 30 and 100 mg/L Cu(2+) addition increased the cumulative biogas yields by up to 43.62 and 20.77% respectively, and brought forward the daily biogas yield peak, while 500 mg/L Cu(2+) addition inhibited biogas production...
July 15, 2017: Biodegradation
https://www.readbyqxmd.com/read/28693554/patient-driven-care-in-the-management-of-prostate-cancer-analysis-of-the-united-states-military-healthcare-system
#18
Muhammad Ali Chaudhary, Jeffrey J Leow, Matthew Mossanen, Ritam Chowdhury, Wei Jiang, Peter A Learn, Joel S Weissman, Steven L Chang
BACKGROUND: Patient preferences are assumed to impact healthcare resource utilization, especially treatment options. There is limited data exploring this phenomenon. We sought to identify factors associated with patients transferring care for prostatectomy, from military to civilian facilities, and the receipt of minimally invasive radical prostatectomy (MIRP). METHODS: Retrospective review of 2006-2010 TRICARE data identified men diagnosed with prostate cancer (ICD-9 185) receiving open radical prostatectomy (ORP; ICD-9: 60...
July 11, 2017: BMC Urology
https://www.readbyqxmd.com/read/28672211/analysis-of-the-functional-gene-structure-and-metabolic-potential-of-microbial-community-in-high-arsenic-groundwater
#19
Ping Li, Zhou Jiang, Yanhong Wang, Ye Deng, Joy D Van Nostrand, Tong Yuan, Han Liu, Dazhun Wei, Jizhong Zhou
Microbial functional potential in high arsenic (As) groundwater ecosystems remains largely unknown. In this study, the microbial community functional composition of nineteen groundwater samples was investigated using a functional gene array (GeoChip 5.0). Samples were divided into low and high As groups based on the clustering analysis of geochemical parameters and microbial functional structures. The results showed that As related genes (arsC, arrA), sulfate related genes (dsrA and dsrB), nitrogen cycling related genes (ureC, amoA, and hzo) and methanogen genes (mcrA, hdrB) in groundwater samples were correlated with As, SO4(2-), NH4(+) or CH4 concentrations, respectively...
June 21, 2017: Water Research
https://www.readbyqxmd.com/read/28649298/neuroimaging-the-traumatized-self-fmri-reveals-altered-response-in-cortical-midline-structures-and-occipital-cortex-during-visual-and-verbal-self-and-other-referential-processing-in-women-with-ptsd
#20
Paul Frewen, Elizabeth Thornley, Daniela Rabellino, Ruth Lanius
Background: Changes to the diagnostic criteria for PTSD in DSM-5 reflect an increased emphasis on negative cognition referring to self and other, including self-blame, and related pervasive negative affective states including for self-conscious emotions such as guilt and shame. Objective: Investigate the neural correlates of valenced self-referential processing (SRP) and other-referential processing (ORP) in persons with PTSD. Method: We compared response to the Visual-Verbal Self-Other Referential Processing Task in an fMRI study of women with (n = 20) versus without (n = 24) PTSD primarily relating to childhood and interpersonal trauma histories using statistical parametric mapping and group independent component analysis...
2017: European Journal of Psychotraumatology
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