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https://www.readbyqxmd.com/read/28332915/effects-of-sampling-interval-on-the-passive-air-sampling-of-atmospheric-pcbs-levels
#1
Ahmet Egemen Sakin, Fatma Esen, Yucel Tasdemir
In this study, we collected Polychlorinated biphenyls (PCBs) using passive air samplers (PASs), between February 4, 2013 and February 2, 2014, with the sampling periods ranging from 10 to 60 days. The samples were collected with PASs that contained polyurethane foam (PUF). With these samples, 87 PCB congeners were analyzed. Sampling coefficient (R) values for the four seasons were calculated using both the high volume air sampler (HVAS) and PAS samples collected with the same time interval. The average of the annual concentrations of 87 PCB congeners, calculated using the R values specific to this study, was 234 ± 175 pg/m(3)...
March 23, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/28331203/the-role-of-axonal-kv1-channels-in-ca3-pyramidal-cell-excitability
#2
Sylvain Rama, Mickael Zbili, Aurélie Fékété, Mónica Tapia, Maria José Benitez, Norah Boumedine, Juan José Garrido, Dominique Debanne
Axonal ion channels control spike initiation and propagation along the axon and determine action potential waveform. We show here that functional suppression of axonal Kv1 channels with local puff of dendrotoxin (DTx), laser or mechanical axotomy significantly increased excitability measured in the cell body. Importantly, the functional effect of DTx puffing or axotomy was not limited to the axon initial segment but was also seen on axon collaterals. In contrast, no effects were observed when DTx was puffed on single apical dendrites or after single dendrotomy...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28330863/bacterial-virulence-phenotypes-of-escherichia-coli-and-host-susceptibility-determine-risk-for-urinary-tract-infections
#3
Henry L Schreiber, Matt S Conover, Wen-Chi Chou, Michael E Hibbing, Abigail L Manson, Karen W Dodson, Thomas J Hannan, Pacita L Roberts, Ann E Stapleton, Thomas M Hooton, Jonathan Livny, Ashlee M Earl, Scott J Hultgren
Urinary tract infections (UTIs) are caused by uropathogenic Escherichia coli (UPEC) strains. In contrast to many enteric E. coli pathogroups, no genetic signature has been identified for UPEC strains. We conducted a high-resolution comparative genomic study using E. coli isolates collected from the urine of women suffering from frequent recurrent UTIs. These isolates were genetically diverse and varied in their urovirulence, that is, their ability to infect the bladder in a mouse model of cystitis. We found no set of genes, including previously defined putative urovirulence factors (PUFs), that were predictive of urovirulence...
March 22, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28326514/complete-response-to-acupuncture-therapy-in-female-patients-with-refractory-interstitial-cystitis-bladder-pain-syndrome
#4
Mehmet Giray Sönmez, Betül Kozanhan
OBJECTIVES: Interstitial Cystitis/Bladder Pain syndrome (IC/BPS) is a considerable issue in urology and gynecology and unfortunately, the treatment options recommended are not fully efficient. Therefore, in this study we aimed to determine the effectiveness of acupuncture treatment in patients with refractory IC/BPS. MATERIAL AND METHODS: 12 refractory IC/BPS female patients received ten sessions of acupuncture twice a week. The visual analog score (VAS), interstitial cystitis symptom index (ICSI), interstitial cystitis problem index (ICPI), O'Leary-Saint symptom score (OSS), Patient Health Questionnaire (PHQ9), Pelvic pain and urgency & frequency patient symptom scale tests (PUF) and maximum voided volume (MVV) was completed in 1st, 3rd, 6th and 12th months following the treatment...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28320951/recurrent-rewiring-and-emergence-of-rna-regulatory-networks
#5
Daniel Wilinski, Natascha Buter, Andrew D Klocko, Christopher P Lapointe, Eric U Selker, Audrey P Gasch, Marvin Wickens
Alterations in regulatory networks contribute to evolutionary change. Transcriptional networks are reconfigured by changes in the binding specificity of transcription factors and their cognate sites. The evolution of RNA-protein regulatory networks is far less understood. The PUF (Pumilio and FBF) family of RNA regulatory proteins controls the translation, stability, and movements of hundreds of mRNAs in a single species. We probe the evolution of PUF-RNA networks by direct identification of the mRNAs bound to PUF proteins in budding and filamentous fungi and by computational analyses of orthologous RNAs from 62 fungal species...
March 20, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28300677/wound-disruption-after-lower-extremity-bypass-surgery-is-a-predictor-of-subsequent-development-of-wound-infection
#6
Faisal Aziz, Tiffany Bohr, Erik B Lehman
OBJECTIVES: Despite advances in endovascular surgery, lower extremity arterial bypass (LEB) remains the gold standard treatment for severe, symptomatic Peripheral Arterial Disease (PAD). With recent changes in healthcare, there has been an increasing emphasis on reducing the hospital length of stay (LOS). The purpose of this study is to identify the postoperative complications, which occur after discharge from hospital, and to find risk factors for developing such complications. METHODS: The 2013 lower extremity revascularization -targeted American College of Surgeons (ACS-NSQIP) database and generalized 2013 general and vascular surgery ACS-NSQIP PUF were used for this study...
March 11, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28293827/temporal-and-spatial-distributions-of-pbdes-in-atmosphere-at-shanghai-rural-regions-china
#7
Yun-Juan Zhu, Dan Sun, Nuo-Er Yang, Yong-Sheng Ding, Wei-Bing Feng, Wen-Jun Hong, Shi-Mao Zhu, Yi-Fan Li
Atmospheric samples were collected using polyurethane foam (PUF) passive air sampling device for every 3 months from June 2012 to May 2013 in Shanghai rural regions in order to investigate the concentrations, profiles, spatial distributions, and seasonal variations of polybrominated diphenyl ethers (PBDEs). Twelve PBDE congeners (BDE-17, BDE-28, BDE-47, BDE-49, BDE-66, BDE-85, BDE-99, BDE-100, BDE-138, BDE-153, BDE-154, and BDE-183) were measured and analyzed by GC-MS. The results showed that detectable PBDEs were examined in all air samples, which indicated that these pollutants are widespread in the research areas...
March 14, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28267997/determination-of-polycyclic-aromatic-hydrocarbons-dibenzothiophene-and-alkylated-homologs-in-the-lichen-hypogymnia-physodes-by-gas-chromatography-using-single-quadrupole-mass-spectrometry-and-time-of-flight-mass-spectrometry
#8
William B Studabaker, Keith J Puckett, Kevin E Percy, Matthew S Landis
Development of the Athabasca Oil Sands Region in northeastern Alberta, Canada has contributed polycyclic aromatic hydrocarbons (PAHs) and polycyclic aromatic compounds (PACs), which include alkyl PAHs and dibenzothiophenes, to the regional environment. A new analytical method was developed for quantification of PAHs and PACs in the epiphytic lichen bioindicator species Hypogymnia physodes for use in the development of receptor models for attribution of PAH and PAC concentrations to anthropogenic and natural emission sources...
February 24, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28260376/inducible-control-of-mrna-transport-using-reprogrammable-rna-binding-proteins
#9
Zhanar Abil, Laura F Gumy, Huimin Zhao, Casper C Hoogenraad
Localization of mRNA is important in a number of cellular processes such as embryogenesis, cellular motility, polarity, and a variety of neurological processes. A synthetic device that controls cellular mRNA localization would facilitate investigations on the significance of mRNA localization in cellular function and allow an additional level of controlling gene expression. In this work, we developed the PUF (Pumilio and FBF homology domain)-assisted localization of RNA (PULR) system, which utilizes a eukaryotic cell's cytoskeletal transport machinery to reposition mRNA within a cell...
March 8, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28258020/lower-extremity-bypass-surgery-on-patients-transferred-from-other-hospitals-is-associated-with-increased-morbidity-and-mortality
#10
Faisal Aziz, Youngmin Chu, Erik B Lehman
BACKGROUND: Despite advances in endovascular surgery, lower extremity arterial bypass remains the gold standard treatment for severe, symptomatic peripheral arterial disease (PAD). Patients who are transferred to other hospitals have generally complex medical problems compared to those patients who are directly admitted from home. The purpose of this study is to identify factors associated with an interfacility transfer in patients with PAD and compare the postoperative outcomes of these patients to those who are directly admitted to the hospital...
February 28, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28254025/assessment-of-chapatti-quality-of-wheat-varieties-based-on-physicochemical-rheological-and-sensory-traits
#11
Manju Kundu, Bhupendar Singh Khatkar, Neelam Gulia
Fifty wheat varieties were assessed for chapatti quality using grain characteristics, dough rheological properties and pasting characteristics. Results revealed that 88% of wheat varieties studied were medium-hard to hard based on kernel texture. Water absorption and damaged starch were found to be important parameters for chapatti quality as both parameters had significant positive effect on the pliability and puffing height of chapatti. Protein content and gluten strength parameters like SDS sedimentation volume, dough stability and gluten index were found to have a negative impact on chapatti quality...
July 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28239027/estrous-cycle-stage-dependent-manner-of-type-i-interferon-stimulated-genes-induction-in-the-bovine-endometrium
#12
Takahiro Shirozu, Hiroki Iwano, Takatoshi Ogiso, Toshiyuki Suzuki, Ahmed Z Balboula, Hanako Bai, Manabu Kawahara, Koji Kimura, Hitomi Takahashi, Bai Rulan, Sung-Woo Kim, Yojiro Yanagawa, Masashi Nagano, Kazuhiko Imakawa, Masashi Takahashi
Interferon tau (IFN-τ) is a ruminant-specific type I IFN secreted by a conceptus before its attachment to the uterus. IFN-τ induces the expression of IFN-stimulated genes (ISGs) via the type I IFN receptor (IFNAR), which is composed of IFNAR1 and IFNAR2 subunits in the endometrium. However, expression patterns of IFNARs during the estrous cycle have not been reported. We hypothesized that the response to a type I IFN changes along with IFNARs and the IFN-regulatory factors (IRFs) driving transcription of IFN signal-related genes and modulating a type I IFN signal during the estrous cycle...
February 26, 2017: Journal of Reproduction and Development
https://www.readbyqxmd.com/read/28231140/food-safety-recommendations-for-determining-doneness-in-consumer-egg-dish-recipes-and-measurement-of-endpoint-temperatures-when-recipes-are-followed
#13
Sandria Godwin, Curtis Maughan, Edgar Chambers
Many consumers do not follow recommended food safety practices for cooking egg dishes, such as pies, quiches, and casseroles, potentially leading to foodborne illnesses such as Salmonellosis. The United States Department of Agriculture (USDA) recommends cooking egg mixtures until the center reaches 71 °C (160 °F). The objectives of this study were to determine what endpoint temperature information consumers receive from egg dish recipes, and if recipes would lead to safe temperatures when followed. Egg dish recipes (n = 226) from 65 websites, 50 cookbooks, and nine magazine titles (multiple issues of each) were analyzed...
June 23, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28205324/evaluation-of-subcutaneous-glucose-monitoring-systems-under-routine-environmental-conditions-in-patients-with-type-1-diabetes
#14
Felix Aberer, Martin Hajnsek, Markus Rumpler, Sabine Zenz, Petra Baumann, Hesham Elsayed, Adelheid Puffing, Gerlies Treiber, Thomas R Pieber, Harald Sourij, Julia K Mader
Continuous and flash glucose monitoring (GM) systems have been established in diabetes care. We compared sensor performance of three commercially available GM systems. 12 patients with type 1 diabetes were included in a single-centre, open-label study where sensor performance of Abbott FreeStyle libre (Abbott), Dexcom G4 Platinum (Dexcom) and Medtronic MiniMed 640G (Medtronic) over 12 hours was compared during mimicked real-life conditions (meals, exercise, hypo- and hyperglycaemia). Sensor performance was determined by fulfilment of ISO 15197:2013 criteria, calculating mean absolute relative difference (MARD) as well as illustrated by Parkes Error grid and Bland-Altman plot...
February 16, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28202356/bladder-capacity-is-a-biomarker-for-a-bladder-centric-versus-systemic-manifestation-in-interstitial-cystitis-bladder-pain-syndrome
#15
Stephen J Walker, Joao Zambon, Karl-Erik Andersson, Carl Langefeld, Catherine A Matthews, Gopal Badlani, Heather Bowman, Robert J Evans
PURPOSE: Interstitial cystitis/bladder pain syndrome (IC/BPS) presents a significant clinical challenge due to symptom heterogeneity and the myriad associated comorbid medical conditions. We recently reported that diminished bladder capacity (BC) may represent a specific IC/BPS sub-phenotype. The objective of this study is to investigate the relationship between anesthetic bladder capacity and clinical findings (urologic and non-urologic) in a cohort of IC/BPS patients who had undergone therapeutic urinary bladder hydrodistention...
February 12, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28199940/measurement-of-polyurethane-foam-air-partition-coefficients-for-semivolatile-organic-compounds-as-a-function-of-temperature-application-to-passive-air-sampler-monitoring
#16
Ana Paula Francisco, Tom Harner, Anita Eng
Polyurethane foam - air partition coefficients (KPUF-air) for 9 polycyclic aromatic hydrocarbons (PAHs), 10 alkyl-substituted PAHs, 4 organochlorine pesticides (OCPs) and dibenzothiophene were measured as a function of temperature over the range 5 °C-35 °C, using a generator column approach. Enthalpies of PUF-to-air transfer (ΔHPUF-air, kJ/mol) were determined from the slopes of log KPUF-air versus 1000/T (K), and have an average value of 81.2 ± 7.03 kJ/mol. The log KPUF-air values at 22 °C ranged from 4...
May 2017: Chemosphere
https://www.readbyqxmd.com/read/28192610/salmonella-inactivation-during-extrusion-of-an-oat-flour-model-food
#17
Nathan M Anderson, Susanne E Keller, Niharika Mishra, Shannon Pickens, Dana Gradl, Tim Hartter, Galen Rokey, Christopher Dohl, Brian Plattner, Stuart Chirtel, Elizabeth M Grasso-Kelley
Little research exists on Salmonella inactivation during extrusion processing, yet many outbreaks associated with low water activity foods since 2006 were linked to extruded foods. The aim of this research was to study Salmonella inactivation during extrusion of a model cereal product. Oat flour was inoculated with Salmonella enterica serovar Agona, an outbreak strain isolated from puffed cereals, and processed using a single-screw extruder at a feed rate of 75 kg/h and a screw speed of 500 rpm. Extrudate samples were collected from the barrel outlet in sterile bags and immediately cooled in an ice-water bath...
February 13, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28138061/pseudouridine-and-n-6-methyladenosine-modifications-weaken-puf-protein-rna-interactions
#18
Pavanapuresan P Vaidyanathan, Ishraq AlSadhan, Dawn K Merriman, Hashim Al-Hashimi, Daniel Herschlag
RNA modifications are ubiquitous in biology, with over 100 distinct modifications. While the vast majority were identified and characterized on abundant non-coding RNA such as tRNA and rRNA, the advent of sensitive sequencing-based approaches has led to the discovery of extensive and regulated modification of eukaryotic messenger RNAs as well. The two most abundant mRNA modifications -pseudouridine (Ψ) and N-6 methyladenosine (m6A)- affect diverse cellular processes including mRNA splicing, localization, translation, and decay and modulate RNA structure...
January 30, 2017: RNA
https://www.readbyqxmd.com/read/28089209/assessment-of-seasonal-variations-in-persistent-organic-pollutants-across-the-region-of-tuscany-using-passive-air-samplers
#19
Victor H Estellano, Karla Pozo, Petra Přibylová, Jana Klánová, Ondřej Audy, Silvano Focardi
Concentrations of persistent organic pollutants (POPs) were measured for an entire year in the region of Tuscany, Italy. Passive air samplers consisting of polyurethane foam (PUF) disks were deployed over four sampling periods of 3-5 months from April 2008 to July 2009 in urban (n = 6) and rural (n = 4) sites. The aim of the study was to characterize the spatial and seasonal variations in selected POPs. The POP concentrations (pg m(-3)) in the air were dominated by dichlorodiphenyltrichloroethane and metabolites (DDTs) and polychlorinated biphenyls (∑7PCBs)...
March 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28088046/application-of-acid-modified-polyurethane-foam-surface-for-detection-and-removing-of-organochlorine-pesticides-from-wastewater
#20
E A Moawed, A M Radwan
The commercial polyurethane foam was acid modified to get an inexpensive adsorbent (AM-PUF) has highly surface polarity and sorption capacity. The elemental analysis, scanning electron microscopy, thermal analysis, ultraviolet/visible/infrared spectroscopies and X-ray diffraction were used for characterization of AM-PUF. The surface of AM-PUF has amorphous character (broadband at 2θ, 21.75°) and contains several active sites e.g. NH, OH, CO, CC and COC groups. The electrical conductivity (σ), iodine value and methylene blue index of AM-PUF are 1...
February 15, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
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