Charles H Adler, Matthew Halverson, Nan Zhang, Holly A Shill, Erika Driver-Dunckley, Shyamal H Mehta, Alireza Atri, John N Caviness, Geidy E Serrano, David R Shprecher, Christine M Belden, Marwan N Sabbagh, Kathy Long, Thomas G Beach
BACKGROUND: While preclinical studies have shown that alpha-synuclein can spread through cell-to-cell transmission whether it can be transmitted between humans is unknown. OBJECTIVES: The aim was to assess the presence of a synucleinopathy in autopsied conjugal couples. METHODS: Neuropathological findings in conjugal couples were categorized as Parkinson's disease (PD), dementia with Lewy bodies (DLB), Alzheimer's disease with Lewy bodies (ADLB), incidental Lewy body disease (ILBD), or no Lewy bodies...
April 10, 2024: Movement Disorders: Official Journal of the Movement Disorder Society